SUPERFAMILY 1.75 HMM library and genome assignments server

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Phosphate binding protein-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Periplasmic binding protein-like II [ 53849]
Superfamily:   Periplasmic binding protein-like II [ 53850] (3)
Family:   Phosphate binding protein-like [ 53851] (40)


Family statistics
Genomes (3,138) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 43,518 340,414 128
Proteins 43,383 339,826 128


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases0.06758Least InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Acting on polysaccharides0InformativeDirect
Enzyme Commission (EC)Pentosyltransferases0InformativeDirect
Enzyme Commission (EC)Intramolecular transferases (mutases)1InformativeInherited

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.0007782Least InformativeDirect
Disease Ontology (DO)disease of mental health0.0000000001345Moderately InformativeDirect
Disease Ontology (DO)neurodegenerative disease0.1564Moderately InformativeInherited
Disease Ontology (DO)schizophrenia0.000000000001129InformativeDirect
Disease Ontology (DO)epilepsy0.000001143InformativeDirect
Disease Ontology (DO)developmental disorder of mental health0.3823InformativeInherited
Disease Ontology (DO)lateral sclerosis0.000001206Highly InformativeDirect
Disease Ontology (DO)bipolar disorder0.000008229Highly InformativeDirect
Disease Ontology (DO)amyotrophic lateral sclerosis0.000008553Highly InformativeDirect
Disease Ontology (DO)focal epilepsy0.03645Highly InformativeInherited
Disease Ontology (DO)specific developmental disorder0.1619Highly InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the eye0.3087Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal eye physiology0.389Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal nervous system electrophysiology0.005931InformativeInherited
Phenotypic Abnormality (PA)Encephalopathy0.01711InformativeInherited
Phenotypic Abnormality (PA)Visual impairment0.1649InformativeInherited
Phenotypic Abnormality (PA)Epileptic encephalopathy0.0003234Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000005046Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.08285Least InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.0000000000004222Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body composition0.00868Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.00000000000005888InformativeDirect
Mammalian Phenotype (MP)abnormal learning/memory/conditioning0.00001013InformativeDirect
Mammalian Phenotype (MP)abnormal sensory capabilities/reflexes/nociception0.0003339InformativeDirect
Mammalian Phenotype (MP)seizures0.0004616InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system electrophysiology0.0005705InformativeDirect
Mammalian Phenotype (MP)abnormal behavioral response to xenobiotic0.0006345InformativeDirect
Mammalian Phenotype (MP)decreased total tissue mass0.0009371InformativeDirect
Mammalian Phenotype (MP)abnormal emotion/affect behavior0.002326InformativeInherited
Mammalian Phenotype (MP)abnormal voluntary movement0.1387InformativeInherited
Mammalian Phenotype (MP)abnormal long term depression0.0000000616Highly InformativeDirect
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.0000001183Highly InformativeDirect
Mammalian Phenotype (MP)abnormal locomotor activation0.000001224Highly InformativeDirect
Mammalian Phenotype (MP)tonic-clonic seizures0.0003426Highly InformativeDirect
Mammalian Phenotype (MP)abnormal aggression-related behavior0.107Highly InformativeInherited
Mammalian Phenotype (MP)abnormal response to novelty0.1447Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.1605Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.7298Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.0001558Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.002675Moderately InformativeInherited
Worm Phenotype (WP)locomotion variant0.03451Moderately InformativeInherited
Worm Phenotype (WP)chemotaxis variant0.000005565InformativeDirect
Worm Phenotype (WP)fat content variant0.0002163InformativeDirect
Worm Phenotype (WP)organism stress response variant0.07302InformativeInherited
Worm Phenotype (WP)aqueous positive chemotaxis variant0.0000009444Highly InformativeDirect
Worm Phenotype (WP)positive chemotaxis defective0.000001689Highly InformativeDirect
Worm Phenotype (WP)thermotaxis variant0.00008237Highly InformativeDirect
Worm Phenotype (WP)pharyngeal pumping irregular0.0001369Highly InformativeDirect
Worm Phenotype (WP)pharyngeal pumping rate variant0.0002372Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)neurophysiology defective0.0000001907InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)nervous system0.04511Least InformativeInherited
Fly Anatomy (FA)larva0.1827Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.09234Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval peripheral nervous system0.02813InformativeInherited
Fly Anatomy (FA)cell component0.03395InformativeInherited
Fly Anatomy (FA)embryonic/larval neuromuscular junction0.0005582Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)embryonic stage0.1588Moderately InformativeInherited
Xenopus DEvelopment stage (XDE)tailbud stage0.0787InformativeInherited
Xenopus DEvelopment stage (XDE)NF stage 35 and 360.00008314Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases0.2828Moderately InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0InformativeDirect
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups0InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases1InformativeInherited
Enzyme Commission (EC)Hydro-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular transferases1InformativeInherited
Enzyme Commission (EC)Acting on polysaccharides0Highly InformativeDirect
Enzyme Commission (EC)Transferring other groups0.3447Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 292 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Periplasmic binding protein-like II domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]