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Amine oxidase N-terminal region superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Cystatin-like [ 54402] (7)
Superfamily:   Amine oxidase N-terminal region [ 54416]
Families:   Amine oxidase N-terminal region [ 54417] (2)


Superfamily statistics
Genomes (525) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,139 10,271 40
Proteins 1,643 5,332 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.000007901 Least Informative Direct
Biological Process (BP) response to stimulus 0.002404 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.4509 Least Informative Inherited
Biological Process (BP) oxidation-reduction process 0 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.0000000000009196 Moderately Informative Direct
Biological Process (BP) response to endogenous stimulus 0.000000005498 Moderately Informative Direct
Biological Process (BP) cell communication 0.00003868 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0003971 Moderately Informative Direct
Biological Process (BP) response to organic substance 0.1485 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.001296 Moderately Informative Inherited
Biological Process (BP) cellular response to inorganic substance 0.000000000000003734 Informative Direct
Biological Process (BP) response to extracellular stimulus 0.0000000000003084 Informative Direct
Biological Process (BP) amine metabolic process 0.0000000000115 Informative Direct
Biological Process (BP) response to nitrogen compound 0.0000001422 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.0000009168 Informative Direct
Biological Process (BP) response to metal ion 0.07959 Informative Inherited
Biological Process (BP) response to copper ion 0 Highly Informative Direct
Biological Process (BP) response to antibiotic 0 Highly Informative Direct
Biological Process (BP) response to nutrient levels 0.00000000000005222 Highly Informative Direct
Biological Process (BP) cellular response to extracellular stimulus 0.000000000006447 Highly Informative Direct
Biological Process (BP) response to drug 0.00000000005132 Highly Informative Direct
Biological Process (BP) cellular response to organonitrogen compound 0.00000002941 Highly Informative Direct
Biological Process (BP) biological adhesion 0.000401 Highly Informative Direct
Molecular Function (MF) binding 0.0964 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.000000000004131 Moderately Informative Direct
Molecular Function (MF) anion binding 0.1393 Moderately Informative Inherited
Molecular Function (MF) sulfur compound binding 0 Informative Direct
Molecular Function (MF) macromolecular complex binding 0.0000000000000395 Informative Direct
Molecular Function (MF) molecular transducer activity 0.0000000009369 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH2 group of donors 0 Highly Informative Direct
Molecular Function (MF) drug binding 0 Highly Informative Direct
Molecular Function (MF) copper ion binding 0 Highly Informative Direct
Molecular Function (MF) heparin binding 0 Highly Informative Direct
Cellular Component (CC) membrane 0.02893 Least Informative Inherited
Cellular Component (CC) extracellular region part 0.0000009581 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.000001384 Moderately Informative Direct
Cellular Component (CC) extracellular space 0.000000003138 Informative Direct
Cellular Component (CC) cell surface 0.0001096 Informative Direct
Cellular Component (CC) cell-cell junction 0.000000000000007429 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)With oxygen as acceptor0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell adhesion0.000000012InformativeDirect
Cellular componentSecreted0.0000363Moderately InformativeDirect
DomainSignal0.0000002678Least InformativeDirect
DomainTransmembrane1Least InformativeInherited
DomainSignal-anchor0.000000127InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionCalcium4.963e-16Moderately InformativeDirect
Molecular functionManganese0.000000000001078Moderately InformativeDirect
Molecular functionCopper0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationDisulfide bond0.0000000007318Least InformativeDirect
Post-translational modificationGlycoprotein0.000007644Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Amine oxidase N-terminal region domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 10 hidden Markov models representing the Amine oxidase N-terminal region superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]