SUPERFAMILY 1.75 HMM library and genome assignments server

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Phenylalanine metabolism regulatory domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ferredoxin-like [ 54861] (59)
Superfamily:   ACT-like [ 55021] (14)
Family:   Phenylalanine metabolism regulatory domain [ 55028] (2)


Family statistics
Genomes (87) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 94 148 2
Proteins 94 148 2


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.000000000007432Least InformativeDirect
Enzyme Commission (EC)Lyases0.00000005526Least InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.0000000000000153Moderately InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.01418Least InformativeInherited
Disease Ontology (DO)disease of mental health0Moderately InformativeDirect
Disease Ontology (DO)schizophrenia0InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal homeostasis0Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cardiovascular system phenotype0.02789Least InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body size0Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0.00498Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.007794Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)decreased body size0InformativeDirect
Mammalian Phenotype (MP)abnormal sensory capabilities/reflexes/nociception0InformativeDirect
Mammalian Phenotype (MP)abnormal heartbeat0.00002736InformativeDirect

Document: MP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)cell0.1645Least InformativeInherited
Zebrafish Anatomy (ZA)multi-tissue structure0.2296Least InformativeInherited
Zebrafish Anatomy (ZA)cavitated compound organ0.3014Least InformativeInherited
Zebrafish Anatomy (ZA)cardiovascular system0.116Moderately InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.1208Moderately InformativeInherited
Zebrafish Anatomy (ZA)hematopoietic cell0.007788InformativeInherited
Zebrafish Anatomy (ZA)hematopoietic system0.009078InformativeInherited
Zebrafish Anatomy (ZA)vasculature0.01329InformativeInherited
Zebrafish Anatomy (ZA)trunk0.2809InformativeInherited
Zebrafish Anatomy (ZA)hematopoietic multipotent progenitor cell0.000002258Highly InformativeDirect
Zebrafish Anatomy (ZA)artery0.0007073Highly InformativeDirect
Zebrafish Anatomy (ZA)axial vasculature0.001556Highly InformativeInherited
Zebrafish Anatomy (ZA)trunk vasculature0.005357Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect
Xenopus DEvelopment stage (XDE)NF stage 660InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.0000000000005145Least InformativeDirect
Enzyme Commission (EC)Lyases0.0000003985Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0.3641Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.00000000000001404InformativeDirect
Enzyme Commission (EC)Intramolecular transferases0.01583InformativeInherited
Enzyme Commission (EC)Transferring other groups0.0008631Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 37 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a ACT-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]