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Tubulin, C-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Bacillus chorismate mutase-like [ 55297] (9)
Superfamily:   Tubulin C-terminal domain-like [ 55307]
Family:   Tubulin, C-terminal domain [ 55308] (3)


Family statistics
Genomes (2,779) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 8,262 45,706 19
Proteins 8,250 45,583 19


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)disease of mental health0.01355Moderately InformativeInherited
Disease Ontology (DO)schizophrenia0.0007274InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0.0001649Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.1649Least InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0.0321Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of forebrain morphology0.06287Moderately InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of the brainstem0.0000005064Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal cortical gyration0.000004171Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.000001149Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.0007577Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.001565Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.001565Least InformativeInherited
Worm Phenotype (WP)cell development variant0.005699Least InformativeInherited
Worm Phenotype (WP)protein protein interaction variant0.00000000172Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.00000007179Moderately InformativeDirect
Worm Phenotype (WP)locomotion variant0.00001877Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.0001262Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.000173Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.005289Moderately InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.01293Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.06986Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.1764Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.4692Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.9158Moderately InformativeInherited
Worm Phenotype (WP)embryonic cell organization biogenesis variant0.00000001121InformativeDirect
Worm Phenotype (WP)neuronal outgrowth variant0.00001278InformativeDirect
Worm Phenotype (WP)spindle variant0.0001615InformativeDirect
Worm Phenotype (WP)cytokinesis variant emb0.0002248InformativeDirect
Worm Phenotype (WP)mitosis variant0.0003336InformativeDirect
Worm Phenotype (WP)cell component localization variant0.001166InformativeInherited
Worm Phenotype (WP)nuclear appearance variant0.004242InformativeInherited
Worm Phenotype (WP)gonad development variant0.01366InformativeInherited
Worm Phenotype (WP)epithelial system development variant0.02054InformativeInherited
Worm Phenotype (WP)nervous system morphology variant0.068InformativeInherited
Worm Phenotype (WP)RNA expression variant0.1217InformativeInherited
Worm Phenotype (WP)egg laying variant0.5972InformativeInherited
Worm Phenotype (WP)locomotion reduced0.6442InformativeInherited
Worm Phenotype (WP)pronucleus centrosomes defective early emb0.00000000003933Highly InformativeDirect
Worm Phenotype (WP)nuclear appearance number defective early emb0.00000000004184Highly InformativeDirect
Worm Phenotype (WP)nucleus defective early emb0.00000000004184Highly InformativeDirect
Worm Phenotype (WP)pronuclear morphology defective early emb0.00000000004184Highly InformativeDirect
Worm Phenotype (WP)pronuclear nuclear appearance defective early emb0.00000000005026Highly InformativeDirect
Worm Phenotype (WP)nuclear morphology variation early emb0.00000000006012Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0.00000007548Highly InformativeDirect
Worm Phenotype (WP)spindle position orientation defective early emb0.000000801Highly InformativeDirect
Worm Phenotype (WP)miRNA expression variant0.000001354Highly InformativeDirect
Worm Phenotype (WP)cuticle morphology variant0.00001887Highly InformativeDirect
Worm Phenotype (WP)exploded through vulva0.00001957Highly InformativeDirect
Worm Phenotype (WP)sluggish0.00005132Highly InformativeDirect
Worm Phenotype (WP)mechanosensation variant0.00013Highly InformativeDirect
Worm Phenotype (WP)male mating variant0.0001573Highly InformativeDirect
Worm Phenotype (WP)male somatic gonad development variant0.0004232Highly InformativeDirect
Worm Phenotype (WP)gonad arm morphology variant0.0007413Highly InformativeDirect
Worm Phenotype (WP)cytoskeleton organization biogenesis variant0.002536Highly InformativeInherited
Worm Phenotype (WP)synapse morphology variant0.00638Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)fertile0.09058Moderately InformativeInherited
Fly Phenotype (FP)male fertile0.0000005755Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)somatic cell0.9688Least InformativeInherited
Fly Anatomy (FA)gonad0.0006364Moderately InformativeDirect
Fly Anatomy (FA)somatic precursor cell0.05805Moderately InformativeInherited
Fly Anatomy (FA)germline cell0.000492InformativeDirect
Fly Anatomy (FA)male organism0.003931InformativeInherited
Fly Anatomy (FA)somatic stem cell0.3317InformativeInherited
Fly Anatomy (FA)type I neuroblast0.00000206Highly InformativeDirect
Fly Anatomy (FA)type II neuroblast0.00001147Highly InformativeDirect
Fly Anatomy (FA)spermatid0.00001289Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

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ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)sensory system0Moderately InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.02918Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.07825Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.09322Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.758Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.000005456Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0.001197Moderately InformativeInherited
Xenopus ANatomical entity (XAN)sensory system0.03136Moderately InformativeInherited
Xenopus ANatomical entity (XAN)epithelium0.000001261InformativeDirect
Xenopus ANatomical entity (XAN)dermal system0.00009789InformativeDirect
Xenopus ANatomical entity (XAN)surface structure0.0006305InformativeDirect
Xenopus ANatomical entity (XAN)peripheral nervous system0.07633InformativeInherited
Xenopus ANatomical entity (XAN)anatomical space0.08589InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0.1797InformativeInherited
Xenopus ANatomical entity (XAN)cell part0.000000000000002815Highly InformativeDirect
Xenopus ANatomical entity (XAN)ciliated cell0.00000000000004949Highly InformativeDirect
Xenopus ANatomical entity (XAN)epithelial cell0.00000000008632Highly InformativeDirect
Xenopus ANatomical entity (XAN)neuron0.000000003891Highly InformativeDirect
Xenopus ANatomical entity (XAN)epidermis0.000006185Highly InformativeDirect
Xenopus ANatomical entity (XAN)vegetal hemisphere0.0001552Highly InformativeDirect
Xenopus ANatomical entity (XAN)archenteron0.001211Highly InformativeInherited
Xenopus ANatomical entity (XAN)cranial nerve0.00536Highly InformativeInherited
Xenopus ANatomical entity (XAN)intersomitic region0.008788Highly InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)vascular system0.004079InformativeInherited

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Tubulin C-terminal domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]