SUPERFAMILY 1.75 HMM library and genome assignments server

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SRF-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   SRF-like [ 55454]
Superfamily:   SRF-like [ 55455]
Family:   SRF-like [ 55456] (4)


Family statistics
Genomes (374) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,017 3,269 7
Proteins 1,016 3,266 7


Disease Ontology (DO)

(
show details) Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body region phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cardiovascular system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)nervous system phenotype0.06075Least InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal cell death0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0Moderately InformativeDirect
Mammalian Phenotype (MP)lethality during fetal growth through weaning0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal synaptic transmission0.0006978Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal muscle physiology0.001533Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.001599Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.008504Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)premature death0InformativeDirect
Mammalian Phenotype (MP)impaired muscle contractility0.00004337InformativeDirect
Mammalian Phenotype (MP)abnormal skeletal muscle morphology0.00012InformativeDirect
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.0004635InformativeDirect
Mammalian Phenotype (MP)abnormal neuron physiology0.0004899InformativeDirect
Mammalian Phenotype (MP)abnormal cardiac muscle contractility0.007071InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.03931InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.04896InformativeInherited
Mammalian Phenotype (MP)enhanced paired-pulse facilitation0.00000002801Highly InformativeDirect
Mammalian Phenotype (MP)abnormal long term potentiation0.00001406Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.00004825Highly InformativeDirect
Mammalian Phenotype (MP)neonatal lethality, complete penetrance0.0005115Highly InformativeDirect

Document: MP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)anatomical cluster0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)cardiovascular system0Moderately InformativeDirect
Zebrafish Anatomy (ZA)pericardial region0InformativeDirect
Zebrafish Anatomy (ZA)heart0Highly InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)brain0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)musculoskeletal system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)embryonic structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)muscle0InformativeDirect
Xenopus ANatomical entity (XAN)epithelium0.0001061InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.02099InformativeInherited
Xenopus ANatomical entity (XAN)head mesoderm0.0000000898Highly InformativeDirect
Xenopus ANatomical entity (XAN)trunk musculature0.000001598Highly InformativeDirect
Xenopus ANatomical entity (XAN)somite0.001273Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect
Xenopus DEvelopment stage (XDE)embryonic stage0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex1Least InformativeInherited
Plant ANatomical entity (PAN)root1Least InformativeInherited
Plant ANatomical entity (PAN)seed1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue0.0197InformativeInherited
Plant ANatomical entity (PAN)root tip0.02134InformativeInherited
Plant ANatomical entity (PAN)embryo sac cell0Highly InformativeDirect
Plant ANatomical entity (PAN)apical meristem0.0001511Highly InformativeDirect
Plant ANatomical entity (PAN)plant ovule0.0007776Highly InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Yeast Phenotype (YP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a SRF-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Yeast Phenotype (YP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]