SUPERFAMILY 1.75 HMM library and genome assignments server

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Nitrile hydratase alpha chain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Nitrile hydratase alpha chain [ 56208]
Superfamily:   Nitrile hydratase alpha chain [ 56209]
Families:   Nitrile hydratase alpha chain [ 56210] (2)


Superfamily statistics
Genomes (228) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 369 3,650 8
Proteins 368 3,616 8


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.00000000166Least InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.000000000000436Moderately InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.000000003978Least InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0.000000000004878Moderately InformativeDirect

Document: EC annotation of SCOP domains

InterPro annotation
Cross references IPR004232 SSF56209 Protein matches
Abstract

This entry represents the alpha subunit, which is a duplication of two structural repeats, each consisting of 4 layers, alpha/beta/beta/alpha.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nitrile hydratase alpha chain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the Nitrile hydratase alpha chain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · Internal database links ]