SUPERFAMILY 1.73 HMM library and genome assignments server


ADP-ribosylation superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (334)
  Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold:   ADP-ribosylation [ 56398]
  unusual fold
Superfamily:   ADP-ribosylation [ 56399] (7)
Families:   ADP-ribosylating toxins [ 56400] (9)
  Ecto-ART [ 82814]
  the two disulfide bridges and N-terminal alpha helices are characteristic for all ecto-ARTs
  Poly(ADP-ribose) polymerase, C-terminal domain [ 56416]
  AvrPphF ORF2, a type III effector [ 111257]
  shares the common structural core with other families; unknown function
  Tpt1/KptA [ 118162]
  Pfam 01885; contains extra N-terminal domain similar to the "winged helix" DNA-binding domain (scop_sf 46785)
  BC2332-like [ 143947]
  minimized common structural core with two large, mainly helical insertions on one side forming dimerization "domain"
  CC0527-like [ 143950]
  Pfam 06108; DUF952


Superfamily statistics
Genomes (601) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 3,191 2,026 53
Proteins 3,176 2,006 50


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Function annotation of SCOP domain superfamilies

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 22 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ADP-ribosylation domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 22 hidden Markov models representing the ADP-ribosylation superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]