SUPERFAMILY 1.73 HMM library and genome assignments server


Hairpin loop containing domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (85)
  Usually dominated by metal ligand, heme, and/or disulfide bridges
Fold:   Hairpin loop containing domain-like [ 57413]
  alpha+beta fold with two crossing loops
Superfamily:   Hairpin loop containing domain-like [ 57414] (3)
Families:   Hairpin loop containing domain [ 57415]
  Anti-platelet protein [ 64556]
  Pan module (APPLE domain) [ 82901]
  probable carbohydrate-binding function


Superfamily statistics
Genomes (118) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 1,195 784 7
Proteins 720 429 7


Functional annotation
General category Other
Detailed category Unknown function

Function annotation of SCOP domain superfamilies

Jump to [ Top of page · SCOP classification · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Hairpin loop containing domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the Hairpin loop containing domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]