SUPERFAMILY 1.75 HMM library and genome assignments server

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LIM domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Glucocorticoid receptor-like (DNA-binding domain) [ 57715]
Superfamily:   Glucocorticoid receptor-like (DNA-binding domain) [ 57716] (18)
Family:   LIM domain [ 57736] (18)


Family statistics
Genomes (0) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 0 0 0
Proteins 0 0 0


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.05306Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.3291Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature0.3938Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.4664Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of connective tissue0.02572Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.04834Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiovascular system physiology0.0615Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal skeletal muscle morphology0.1558Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating metabolite concentration0.1612Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.4054Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal myocardium morphology0.0005519InformativeDirect
Phenotypic Abnormality (PA)Abnormal circulating protein level0.0006079InformativeDirect
Phenotypic Abnormality (PA)Abnormal adipose tissue morphology0.009411InformativeInherited
Phenotypic Abnormality (PA)Arrhythmia0.01371InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature of the limbs0.07697InformativeInherited
Phenotypic Abnormality (PA)Sudden cardiac death0.00005624Highly InformativeDirect
Phenotypic Abnormality (PA)Lipodystrophy0.0001195Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature of the lower limbs0.0008192Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.01771Least InformativeInherited
Mammalian Phenotype (MP)abnormal muscle physiology0.007644Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.03569Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2203Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.3283Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.8376Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal response to injury0.0008807InformativeDirect
Mammalian Phenotype (MP)impaired muscle contractility0.003042InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle contractility0.01935InformativeInherited
Mammalian Phenotype (MP)abnormal heart left ventricle morphology0.0004977Highly InformativeDirect
Mammalian Phenotype (MP)dilated heart0.03117Highly InformativeInherited
Mammalian Phenotype (MP)abnormal lung size0.09435Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell morphology variant0.0000381Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.006784Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.02089Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.02089Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.0263Least InformativeInherited
Worm Phenotype (WP)protein expression variant0.00123Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.2119Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.3247Moderately InformativeInherited
Worm Phenotype (WP)mitochondria morphology variant0.00000003636InformativeDirect
Worm Phenotype (WP)body wall muscle sarcomere morphology variant0.0000000722InformativeDirect
Worm Phenotype (WP)muscle cell physiology variant0.000000448InformativeDirect
Worm Phenotype (WP)level of protein expression variant0.000003381InformativeDirect
Worm Phenotype (WP)cell component localization variant0.001351InformativeInherited
Worm Phenotype (WP)protein metabolism variant0.003713InformativeInherited
Worm Phenotype (WP)muscle cell attachment variant0.000000009939Highly InformativeDirect
Worm Phenotype (WP)protein expression reduced0.0000008044Highly InformativeDirect
Worm Phenotype (WP)protein degradation variant0.0001569Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)anatomical cluster0.2478Least InformativeInherited
Zebrafish Anatomy (ZA)cavitated compound organ0.357Least InformativeInherited
Zebrafish Anatomy (ZA)cardiovascular system0.04208Moderately InformativeInherited
Zebrafish Anatomy (ZA)pericardial region0.08587InformativeInherited
Zebrafish Anatomy (ZA)heart0.003678Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0.002115Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.0432Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.05379Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.05647Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.09297Least InformativeInherited
Xenopus ANatomical entity (XAN)nervous system0.1436Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.1925Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.00161Moderately InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.003562Moderately InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.02577Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.1498Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus0.3483Moderately InformativeInherited
Xenopus ANatomical entity (XAN)brain0.4503Moderately InformativeInherited
Xenopus ANatomical entity (XAN)cardiovascular system0.00002698InformativeDirect
Xenopus ANatomical entity (XAN)skeletal system0.0005407InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0.0005997InformativeDirect
Xenopus ANatomical entity (XAN)neuroectoderm0.001258InformativeInherited
Xenopus ANatomical entity (XAN)forebrain0.01077Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.08434Least InformativeInherited
Xenopus DEvelopment stage (XDE)adult frog stage0.0006313Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)microgametophyte0Least InformativeDirect
Plant ANatomical entity (PAN)pollen tube cell0.0007842InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)L mature pollen stage0.0003341InformativeDirect
Plant structure DEvelopment stage (PDE)M germinated pollen stage0.0008805InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0.0006299Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.04667Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0.0000002255InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen0.00000000002335Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 127 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Glucocorticoid receptor-like (DNA-binding domain) domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]