SUPERFAMILY 1.75 HMM library and genome assignments server

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FYVE, a phosphatidylinositol-3-phosphate binding domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   FYVE/PHD zinc finger [ 57902]
Superfamily:   FYVE/PHD zinc finger [ 57903] (3)
Family:   FYVE, a phosphatidylinositol-3-phosphate binding domain [ 57904] (6)


Family statistics
Genomes (143) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 367 907 6
Proteins 367 907 6


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0.0000003973Least InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0.00000000003237Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0.0000001859Moderately InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase0InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.3628Least InformativeInherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.4008Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.5665Least InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord morphology0.0001884InformativeDirect
Mammalian Phenotype (MP)abnormal pancreas physiology0.00856InformativeInherited
Mammalian Phenotype (MP)abnormal endocrine gland physiology0.01623InformativeInherited
Mammalian Phenotype (MP)abnormal insulin secretion0.01368Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.00000004631Least InformativeDirect
Worm Phenotype (WP)blast cell physiology variant0.00000004631Least InformativeDirect
Worm Phenotype (WP)cell death variant0.000000000000001256Moderately InformativeDirect
Worm Phenotype (WP)chemical response variant0.329Moderately InformativeInherited
Worm Phenotype (WP)endocytic transport defect0.00000000001338InformativeDirect
Worm Phenotype (WP)acetylcholinesterase inhibitor response variant0.002689InformativeInherited
Worm Phenotype (WP)drug resistant0.008031InformativeInherited
Worm Phenotype (WP)coelomocyte uptake defective0Highly InformativeDirect
Worm Phenotype (WP)acetylcholinesterase inhibitor resistant0.0009348Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0.2278Least InformativeInherited
Yeast Phenotype (YP)chromosome/plasmid maintenance0.03685InformativeInherited
Yeast Phenotype (YP)chemical compound excretion0.0002296Highly InformativeDirect
Yeast Phenotype (YP)protein/peptide modification0.0002821Highly InformativeDirect
Yeast Phenotype (YP)transposable element transposition0.0005091Highly InformativeDirect
Yeast Phenotype (YP)protein/peptide distribution0.000802Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0.1191Least InformativeInherited
Fly Anatomy (FA)somatic cell0.6517Least InformativeInherited
Fly Anatomy (FA)late embryo0.1924Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval circulatory system0.06234InformativeInherited
Fly Anatomy (FA)nephrocyte0.0007558Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)cell0Least InformativeDirect
Zebrafish Anatomy (ZA)head0Moderately InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0.00002277Least InformativeDirect
Enzyme Commission (EC)Hydrolases0.1569Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0.0000001153Moderately InformativeDirect
Enzyme Commission (EC)Acyltransferases0.000005017Moderately InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0.0001068Moderately InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0.000000000000001101InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0.00000001153InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase0.000000000000005797Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 41 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a FYVE/PHD zinc finger domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]