SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Leucine zipper domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Leucine zipper domain [ 57959]
Family:   Leucine zipper domain [ 57960] (16)


Family statistics
Genomes (101) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 900 2,270 22
Proteins 900 2,270 22


Disease Ontology (DO)

(
show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.005332Least InformativeInherited
Disease Ontology (DO)hematologic cancer0.0002352Moderately InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.02353Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.2833Least InformativeInherited
Mammalian Phenotype (MP)adipose tissue phenotype0.01923Moderately InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.05829Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.08777Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin morphology0.1604Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.384Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)seizures0.00309InformativeInherited
Mammalian Phenotype (MP)abnormal hepatobiliary system physiology0.008937InformativeInherited
Mammalian Phenotype (MP)abnormal white adipose tissue morphology0.08949InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.1122InformativeInherited
Mammalian Phenotype (MP)abnormal bone ossification0.2599InformativeInherited
Mammalian Phenotype (MP)abnormal epidermal layer morphology0.2774InformativeInherited
Mammalian Phenotype (MP)abnormal adipose tissue amount0.8059InformativeInherited
Mammalian Phenotype (MP)thick epidermis0.0005548Highly InformativeDirect
Mammalian Phenotype (MP)absence seizures0.0005843Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.04708Least InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.0002237Moderately InformativeDirect
Worm Phenotype (WP)chemical response variant0.9056Moderately InformativeInherited
Worm Phenotype (WP)transgene expression reduced0.0000004384InformativeDirect
Worm Phenotype (WP)organism pathogen response variant0.004864InformativeInherited
Worm Phenotype (WP)RNA expression variant0.04381InformativeInherited
Worm Phenotype (WP)pathogen susceptibility increased0.0005725Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.00104Least InformativeInherited
Fly Phenotype (FP)lethal - all die before end of P-stage0.0199Moderately InformativeInherited
Fly Phenotype (FP)lethal - all die before end of first instar larval stage0.0008246InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0.574Least InformativeInherited
Fly Anatomy (FA)epithelium0.297Moderately InformativeInherited
Fly Anatomy (FA)presumptive embryonic/larval system0.08258InformativeInherited
Fly Anatomy (FA)cuboidal/columnar epithelium0.1495InformativeInherited
Fly Anatomy (FA)embryonic epidermis0.02788Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.1086Least InformativeInherited
Zebrafish Anatomy (ZA)hematopoietic cell0.03746InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)root0.4943Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue0.02172InformativeInherited
Plant ANatomical entity (PAN)root tip0.02343InformativeInherited
Plant ANatomical entity (PAN)plant axis elongation zone0.0006723Highly InformativeDirect
Plant ANatomical entity (PAN)primary root0.0006763Highly InformativeDirect
Plant ANatomical entity (PAN)stele0.006289Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 48 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Leucine zipper domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]