SUPERFAMILY 1.75 HMM library and genome assignments server

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SNARE fusion complex family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   SNARE fusion complex [ 58038]
Family:   SNARE fusion complex [ 58039] (11)


Family statistics
Genomes (276) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,390 3,536 27
Proteins 1,154 3,034 27


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)benign neoplasm0.03736Moderately InformativeInherited
Disease Ontology (DO)organ system benign neoplasm0.002325InformativeInherited
Disease Ontology (DO)endocrine organ benign neoplasm0.00007859Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the face0.1293Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.1879Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.3766Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of movement0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.04555Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.08849Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.09887Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1613Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system physiology0.1802Moderately InformativeInherited
Phenotypic Abnormality (PA)Seizures0InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the hip joint0.0007028InformativeDirect
Phenotypic Abnormality (PA)Abnormal nervous system electrophysiology0.001064InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.001658InformativeInherited
Phenotypic Abnormality (PA)Abnormal facial shape0.002752InformativeInherited
Phenotypic Abnormality (PA)Abnormality of prenatal development or birth0.01673InformativeInherited
Phenotypic Abnormality (PA)Functional abnormality of the gastrointestinal tract0.02458InformativeInherited
Phenotypic Abnormality (PA)Neurological speech impairment0.05604InformativeInherited
Phenotypic Abnormality (PA)Abnormal reflex0.1519InformativeInherited
Phenotypic Abnormality (PA)Muscle weakness0.2045InformativeInherited
Phenotypic Abnormality (PA)EEG with spike-wave complexes0.000003502Highly InformativeDirect
Phenotypic Abnormality (PA)Areflexia0.000005747Highly InformativeDirect
Phenotypic Abnormality (PA)Decreased fetal movement0.0001752Highly InformativeDirect
Phenotypic Abnormality (PA)Dysarthria0.0002044Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the stomach0.005186Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of esophagus physiology0.007073Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.1808Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.8608Least InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.0344Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.3542Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.4136Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron differentiation0.03413InformativeInherited
Mammalian Phenotype (MP)abnormal neurotransmitter secretion0.00004226Highly InformativeDirect
Mammalian Phenotype (MP)enhanced paired-pulse facilitation0.00004488Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)multi-tissue structure0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)central nervous system0Moderately InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)pollen tube cell0.0000001325InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 25 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a SNARE fusion complex domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]