SUPERFAMILY 1.75 HMM library and genome assignments server

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Integrin alpha N-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   Integrin alpha N-terminal domain [ 69318]
Family:   Integrin alpha N-terminal domain [ 69319]


Family statistics
Genomes (148) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,510 3,994 2
Proteins 1,491 3,967 2


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)infertility0.00008224Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the urinary system physiology0.0008848Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of prenatal development or birth0.0002236InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.009677Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.04026Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.1569Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.4385Least InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.3473Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.4354Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte physiology0.8077Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell migration0.00841InformativeInherited
Mammalian Phenotype (MP)abnormal cell adhesion0.00000002853Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cellular extravasation0.000003517Highly InformativeDirect
Mammalian Phenotype (MP)abnormal respiratory conducting tube morphology0.0007844Highly InformativeDirect
Mammalian Phenotype (MP)abnormal ureter morphology0.007714Highly InformativeInherited
Mammalian Phenotype (MP)neurodegeneration0.06568Highly InformativeInherited

Document: MP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Integrin alpha N-terminal domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]