SUPERFAMILY 1.75 HMM library and genome assignments server

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Thioesterase domain of polypeptide, polyketide and fatty acid synthases family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   alpha/beta-Hydrolases [ 53473]
Superfamily:   alpha/beta-Hydrolases [ 53474] (41)
Family:   Thioesterase domain of polypeptide, polyketide and fatty acid synthases [ 69584] (4)


Family statistics
Genomes (173) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 259 1,388 6
Proteins 259 1,387 6


Enzyme Commission (EC)

(
show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0.000003809Least InformativeDirect
Enzyme Commission (EC)Ligases0.006621Least InformativeInherited
Enzyme Commission (EC)Lyases0.001397Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases0.006412Least InformativeInherited
Enzyme Commission (EC)Acting on the CH-CH group of donors0.000000004558Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0.00000002418Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.000006465Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.00000849Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds0.00003586Moderately InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases0.000000000000001037InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.0000000001222InformativeDirect
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0.0000001163InformativeDirect
Enzyme Commission (EC)Oleoyl-[acyl-carrier-protein] hydrolase0Highly InformativeDirect
Enzyme Commission (EC)Fatty-acid synthase0Highly InformativeDirect
Enzyme Commission (EC)Enoyl-[acyl-carrier-protein] reductase (NADPH, B-s0Highly InformativeDirect
Enzyme Commission (EC)3-oxoacyl-[acyl-carrier-protein] reductase0Highly InformativeDirect
Enzyme Commission (EC)3-hydroxypalmitoyl-[acyl-carrier-protein] dehydrat0Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-acetyltransferase3.476e-16Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-malonyltransferase0.0000000000004195Highly InformativeDirect
Enzyme Commission (EC)Beta-ketoacyl-acyl-carrier-protein synthase I0.000000006691Highly InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.01142Least InformativeInherited
Enzyme Commission (EC)Hydrolases0.02252Least InformativeInherited
Enzyme Commission (EC)Transferases0.05137Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.000000003974Moderately InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0.0000132Moderately InformativeDirect
Enzyme Commission (EC)Lyases0.00561Moderately InformativeInherited
Enzyme Commission (EC)Ligases0.01125Moderately InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0.0000000001507InformativeDirect
Enzyme Commission (EC)Acting on the CH-CH group of donors0.00000002122InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.0000104InformativeDirect
Enzyme Commission (EC)Hydro-lyases0.00001883InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds0.0001294InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases0.000000000000003457Highly InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.0000000002449Highly InformativeDirect
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0.0000001976Highly InformativeDirect

Document: EC annotation of SCOP domains

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Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 255 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a alpha/beta-Hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Enzyme Commission (EC) · Internal database links ]