SUPERFAMILY 1.75 HMM library and genome assignments server

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gamma-adaptin C-terminal appendage domain-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Immunoglobulin-like beta-sandwich [ 48725] (28)
Superfamily:   Clathrin adaptor appendage domain [ 49348] (3)
Family:   gamma-adaptin C-terminal appendage domain-like [ 74857] (3)


Family statistics
Genomes (103) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 450 1,171 9
Proteins 450 1,171 9


Disease Ontology (DO)

(
show details) Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal homeostasis0Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)abnormal reproductive system physiology0.006651Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal body size0.0347Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal body composition0.2175Moderately InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.257Moderately InformativeInherited
Mammalian Phenotype (MP)postnatal growth retardation0.001621InformativeInherited
Mammalian Phenotype (MP)decreased total tissue mass0.01127InformativeInherited
Mammalian Phenotype (MP)abnormal circulating glucose level0.0184InformativeInherited
Mammalian Phenotype (MP)decreased body size0.02478InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.03931InformativeInherited
Mammalian Phenotype (MP)decreased birth weight0.0000008749Highly InformativeDirect
Mammalian Phenotype (MP)neonatal lethality, incomplete penetrance0.0001023Highly InformativeDirect
Mammalian Phenotype (MP)decreased circulating glucose level0.0001077Highly InformativeDirect
Mammalian Phenotype (MP)reduced fertility0.0003791Highly InformativeDirect

Document: MP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)brain0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)alimentary system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)musculoskeletal system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Clathrin adaptor appendage domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Xenopus Anatomy (XA) · Internal database links ]