SUPERFAMILY 1.75 HMM library and genome assignments server

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Clathrin coat assembly domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Profilin-like [ 55769] (10)
Superfamily:   SNARE-like [ 64356] (4)
Family:   Clathrin coat assembly domain [ 75521] (2)


Family statistics
Genomes (503) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,734 7,612 5
Proteins 2,731 7,609 5


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.2092Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.2814Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0.3109Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal lip morphology0.04855InformativeInherited
Phenotypic Abnormality (PA)Abnormal facial shape0.0554InformativeInherited
Phenotypic Abnormality (PA)Neurological speech impairment0.09658InformativeInherited
Phenotypic Abnormality (PA)Wide mouth0.0001768Highly InformativeDirect
Phenotypic Abnormality (PA)Coarse facial features0.0007094Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the philtrum0.01094Highly InformativeInherited

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0Least InformativeDirect
Worm Phenotype (WP)blast cell physiology variant0Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.00008696Least InformativeDirect
Worm Phenotype (WP)cell development variant0.002621Least InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.0000101Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.0000101Moderately InformativeDirect
Worm Phenotype (WP)developmental morphology variant0.00001016Moderately InformativeDirect
Worm Phenotype (WP)adult body morphology variant0.00001022Moderately InformativeDirect
Worm Phenotype (WP)body morphology variant0.00001117Moderately InformativeDirect
Worm Phenotype (WP)cell type morphology variant0.00001362Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.00294Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.01464Moderately InformativeInherited
Worm Phenotype (WP)protein expression variant0.1706Moderately InformativeInherited
Worm Phenotype (WP)tail morphology variant0.00001424InformativeDirect
Worm Phenotype (WP)vesicle morphology variant0.00008839InformativeDirect
Worm Phenotype (WP)acetylcholinesterase inhibitor response variant0.00009611InformativeDirect
Worm Phenotype (WP)pattern protein expression variant0.0002458InformativeDirect
Worm Phenotype (WP)drug resistant0.0003183InformativeDirect
Worm Phenotype (WP)alimentary system development variant0.004679InformativeInherited
Worm Phenotype (WP)nervous system morphology variant0.08202InformativeInherited
Worm Phenotype (WP)dumpy0.000004269Highly InformativeDirect
Worm Phenotype (WP)acetylcholinesterase inhibitor resistant0.00003107Highly InformativeDirect
Worm Phenotype (WP)intestinal development variant0.00003177Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)intracellular transport0.02104InformativeInherited

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

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Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a SNARE-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]