SUPERFAMILY 1.75 HMM library and genome assignments server

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Cullin homology domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   Cullin homology domain [ 75631]
Superfamily:   Cullin homology domain [ 75632]
Family:   Cullin homology domain [ 75633] (2)


Family statistics
Genomes (484) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,505 6,851 4
Proteins 2,495 6,827 4


Mouse Phenotype (MP)

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show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.01636Least InformativeInherited
Mammalian Phenotype (MP)abnormal embryo morphology0.008428Moderately InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.1641Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal prenatal body size0.001465InformativeInherited
Mammalian Phenotype (MP)abnormal embryonic growth/weight/body size0.002359InformativeInherited
Mammalian Phenotype (MP)embryonic lethality prior to organogenesis0.006521InformativeInherited
Mammalian Phenotype (MP)embryonic lethality between implantation and somite formation, complete penetrance0.0004024Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.0007797Least InformativeDirect
Worm Phenotype (WP)cell development variant0.002545Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.000007587Moderately InformativeDirect
Worm Phenotype (WP)protein expression variant0.0002994Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.0006959Moderately InformativeDirect
Worm Phenotype (WP)cell death variant0.0008052Moderately InformativeDirect
Worm Phenotype (WP)germ cell differentiation variant0.002347Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.0032Moderately InformativeInherited
Worm Phenotype (WP)germ cell development variant0.01084Moderately InformativeInherited
Worm Phenotype (WP)accumulated germline cell corpses0.0000000001336InformativeDirect
Worm Phenotype (WP)pattern protein expression variant0.000000000865InformativeDirect
Worm Phenotype (WP)chemical hypersensitive0.000000003361InformativeDirect
Worm Phenotype (WP)life span variant0.00002998InformativeDirect
Worm Phenotype (WP)apoptosis increased0.000000000002414Highly InformativeDirect
Worm Phenotype (WP)spontaneous mutation rate increased0.0000004629Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)somatic cell0Least InformativeDirect
Fly Anatomy (FA)gonad0Moderately InformativeDirect
Fly Anatomy (FA)developing material anatomical entity0Moderately InformativeDirect
Fly Anatomy (FA)female-specific anatomical entity0.0005615Moderately InformativeDirect
Fly Anatomy (FA)epithelium0.07172Moderately InformativeInherited
Fly Anatomy (FA)female germline cyst0.0001473InformativeDirect
Fly Anatomy (FA)epithelial cell0.0006476Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Cullin homology domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]