SUPERFAMILY 1.75 HMM library and genome assignments server

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RUNT domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Common fold of diphtheria toxin/transcription factors/cytochrome f [ 49379] (10)
Superfamily:   p53-like transcription factors [ 49417] (7)
Family:   RUNT domain [ 81318]


Family statistics
Genomes (143) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 491 1,392 6
Proteins 491 1,392 6


Mouse Phenotype (MP)

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show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal homeostasis0Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0Least InformativeDirect
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)immune system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)abnormal lymphocyte cell number0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal axial skeleton morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell morphology/development0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal immune system organ morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body size0Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body composition0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal T cell morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal professional antigen presenting cell morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal skin adnexa morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)lethality during fetal growth through weaning0Moderately InformativeDirect
Mammalian Phenotype (MP)increased hematopoietic cell number0Moderately InformativeDirect
Mammalian Phenotype (MP)decreased hematopoietic cell number0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal myeloid cell morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)decreased body size0InformativeDirect
Mammalian Phenotype (MP)perinatal lethality0InformativeDirect
Mammalian Phenotype (MP)postnatal lethality0InformativeDirect
Mammalian Phenotype (MP)abnormal skeleton development0InformativeDirect
Mammalian Phenotype (MP)decreased T cell number0InformativeDirect
Mammalian Phenotype (MP)abnormal bone ossification0InformativeDirect
Mammalian Phenotype (MP)decreased total tissue mass0InformativeDirect
Mammalian Phenotype (MP)abnormal bone mineralization0Highly InformativeDirect
Mammalian Phenotype (MP)postnatal lethality, incomplete penetrance0Highly InformativeDirect

Document: MP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0Least InformativeDirect

Document: FP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)head0Moderately InformativeDirect
Zebrafish Anatomy (ZA)skeletal system0InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)musculoskeletal system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)multi-tissue structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)neuroectoderm0InformativeDirect
Xenopus ANatomical entity (XAN)skeletal system0InformativeDirect
Xenopus ANatomical entity (XAN)solid compound organ0InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0InformativeDirect
Xenopus ANatomical entity (XAN)splanchnocranium0Highly InformativeDirect
Xenopus ANatomical entity (XAN)skeletal tissue0Highly InformativeDirect
Xenopus DEvelopment stage (XDE)embryonic stage0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Fly Phenotype (FP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 26 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a p53-like transcription factors domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Fly Phenotype (FP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]