SUPERFAMILY 1.73 HMM library and genome assignments server


Clc chloride channel superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (50)
  Does not include proteins in the immune system
Fold:   Clc chloride channel [ 81341]
  core: 18 transmembrane helices
Superfamily:   Clc chloride channel [ 81340]
Families:   Clc chloride channel [ 69912]
  duplication: consist of two similar structural parts


Superfamily statistics
Genomes (867) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 2,601 2,201 6
Proteins 2,596 2,200 6


Functional annotation
General category Processes_IC
Detailed category Ion metabolism and transport

Function annotation of SCOP domain superfamilies
InterPro annotation
Cross references IPR014743 SSF81340 Protein matches
Abstract

This entry represents the core domain of the cholide ion channel.


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clc chloride channel domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Clc chloride channel superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]