SUPERFAMILY 1.75 HMM library and genome assignments server

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Ubiquitin carboxyl-terminal hydrolase, UCH family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Cysteine proteinases [ 54000]
Superfamily:   Cysteine proteinases [ 54001] (22)
Family:   Ubiquitin carboxyl-terminal hydrolase, UCH [ 82568] (5)


Family statistics
Genomes (506) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 7,918 21,955 6
Proteins 7,911 21,935 6


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Ubiquitinyl hydrolase 10InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the digestive system0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of higher mental function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of body weight0.04041Moderately InformativeInherited
Phenotypic Abnormality (PA)Obesity0.0006867InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.5664Least InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.7499Moderately InformativeInherited
Mammalian Phenotype (MP)embryonic lethality prior to organogenesis0.1919InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.000000007282Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.0000001652Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.0003635Least InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.00000000002889Moderately InformativeDirect
Worm Phenotype (WP)locomotion variant0.0000000002433Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.00000001131Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.00000764Moderately InformativeDirect
Worm Phenotype (WP)neuron migration variant0InformativeDirect
Worm Phenotype (WP)maintenance of gene silencing variant0.0009854Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)behavior defective0.0001859InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)tagma0Least InformativeDirect
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0.001506Least InformativeInherited
Zebrafish Anatomy (ZA)multi-tissue structure0.1121Least InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.1412Least InformativeInherited
Zebrafish Anatomy (ZA)head0.5496Moderately InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.6224Moderately InformativeInherited
Zebrafish Anatomy (ZA)post-vent region0.00003129InformativeDirect
Zebrafish Anatomy (ZA)skeletal system0.001449InformativeInherited
Zebrafish Anatomy (ZA)pharyngeal arch0.001521InformativeInherited
Zebrafish Anatomy (ZA)pericardial region0.002809InformativeInherited
Zebrafish Anatomy (ZA)trunk0.0279InformativeInherited
Zebrafish Anatomy (ZA)surface structure0.9902InformativeInherited
Zebrafish Anatomy (ZA)pharyngeal arch cartilage0.000001045Highly InformativeDirect
Zebrafish Anatomy (ZA)pericardium0.00000216Highly InformativeDirect
Zebrafish Anatomy (ZA)olfactory region0.000003052Highly InformativeDirect
Zebrafish Anatomy (ZA)neurocranium0.00002354Highly InformativeDirect
Zebrafish Anatomy (ZA)ventral mandibular arch0.0002689Highly InformativeDirect
Zebrafish Anatomy (ZA)chondrocranium cartilage0.02288Highly InformativeInherited
Zebrafish Anatomy (ZA)fin0.421Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)plant sperm cell0.0003582InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Ubiquitinyl hydrolase 10Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 116 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Cysteine proteinases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]