SUPERFAMILY 1.75 HMM library and genome assignments server

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TSP-1 type 1 repeat family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   TSP-1 type 1 repeat [ 82894]
Superfamily:   TSP-1 type 1 repeat [ 82895]
Family:   TSP-1 type 1 repeat [ 82896]


Family statistics
Genomes (64) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 239 681 2
Proteins 144 395 1


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Metalloendopeptidases0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.285Least InformativeInherited
Disease Ontology (DO)connective tissue disease0.0001237Moderately InformativeDirect
Disease Ontology (DO)nervous system cancer0.3345Moderately InformativeInherited
Disease Ontology (DO)arthritis0.00005094InformativeDirect
Disease Ontology (DO)peripheral nervous system neoplasm0.1037InformativeInherited
Disease Ontology (DO)neurofibroma0.0000003753Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of limbs0.1816Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the immune system0.3503Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.6953Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.83Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.3122Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal anterior eye segment morphology0.3581Moderately InformativeInherited
Phenotypic Abnormality (PA)Unusual infection0.4933Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.5524Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of complement system0.00004598InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lens0.1711InformativeInherited
Phenotypic Abnormality (PA)Abnormal lower limb bone morphology0.2418InformativeInherited
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.481InformativeInherited
Phenotypic Abnormality (PA)Recurrent infections0.7536InformativeInherited
Phenotypic Abnormality (PA)Recurrent Neisserial infections0.000001824Highly InformativeDirect
Phenotypic Abnormality (PA)Ectopia lentis0.0009665Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of epiphysis morphology0.07609Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal bone structure0.3618Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal compact bone morphology0.06643Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)pericellular component development variant0.0000008464Moderately InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo1Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system1Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue1Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.6044Moderately InformativeInherited
Xenopus ANatomical entity (XAN)tail region0.6927Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)urinary system0.2611InformativeInherited
Xenopus ANatomical entity (XAN)tail bud0.1174Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.2191Least InformativeInherited
Xenopus DEvelopment stage (XDE)premetamorphosis stage0.0000000000001433Highly InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Metalloendopeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a TSP-1 type 1 repeat domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]