SUPERFAMILY 1.73 HMM library and genome assignments server


Glycoside hydrolase/deacetylase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   7-stranded beta/alpha barrel [ 51988] (3)
  variant of beta/alpha barrel; parallel beta-sheet barrel, closed, n=7, S=8; strand order 1234567; some members may have fewer strands
Superfamily:   Glycoside hydrolase/deacetylase [ 88713] (7)
Families:   4-alpha-glucanotransferase, N-terminal domain [ 89554]
  family 57 glycoside hydrolase; overall domain organization is similar to that of the alpha-mannosidase family
  alpha-mannosidase [ 88714] (2)
  family 38 glycoside hydrolase; overall domain organization is similar to that of the 4-alpha-glucanotransferase family
  AmyC N-terminal domain-like [ 102189] (2)
  NodB-like polysaccharide deacetylase [ 89559] (6)
  variant of beta/alpha barrel; parallel beta-sheet barrel, closed, n=6, S=8; strand order 123456
  LamB/YcsF-like [ 117449] (3)
  Pfam 03746
  PA1517-like [ 141965]
  seven-stranded barrel with a detectable sequence similarity to the six-stranded barrel NodB-like family; member of the same Pfam family (Pfam 01522)
  Divergent polysaccharide deacetylase [ 141968]
  Pfam 04748


Superfamily statistics
Genomes (1,110) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 6,192 6,943 23
Proteins 6,181 6,933 23


Functional annotation
General category Metabolism
Detailed category Other enzymes

Function annotation of SCOP domain superfamilies
InterPro annotation
Cross references IPR011330 SSF88713 Protein matches
Abstract

This entry represents a structural motif found in glycoside hydrolase families 38 (, e.g. alpha-mannosidase) [PubMed12960159] and 57 (, e.g. 4-alpha-glucanotransferase, N-terminal) [PubMed12618437], as well as in NodB-like polysaccharide deacetylase and in some hypothetical proteins (e.g. TT1467, N-terminal domain). This domain consists of a 7-stranded beta/alpha barrel, although in some families the beta-barrels may be distorted and may vary in the number of strands.


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 16 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Glycoside hydrolase/deacetylase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 16 hidden Markov models representing the Glycoside hydrolase/deacetylase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]