SUPERFAMILY 1.75 HMM library and genome assignments server

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Proprotein convertase P-domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Galactose-binding domain-like [ 49784]
Superfamily:   Galactose-binding domain-like [ 49785] (32)
Family:   Proprotein convertase P-domain [ 89249] (3)


Family statistics
Genomes (242) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 515 1,482 5
Proteins 515 1,482 5


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0Moderately InformativeDirect
Enzyme Commission (EC)Furin3.476e-16Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details) Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.2574Least InformativeInherited
Mammalian Phenotype (MP)limbs/digits/tail phenotype0.01071Moderately InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.02397Moderately InformativeInherited
Mammalian Phenotype (MP)embryonic lethality prior to organogenesis0.0002074InformativeDirect
Mammalian Phenotype (MP)abnormal autopod morphology0.0005174InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)pericellular component development variant0Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.001754Moderately InformativeInherited
Worm Phenotype (WP)organism segment morphology variant0.001754Moderately InformativeInherited
Worm Phenotype (WP)developmental morphology variant0.00176Moderately InformativeInherited
Worm Phenotype (WP)adult body morphology variant0.001765Moderately InformativeInherited
Worm Phenotype (WP)body morphology variant0.001856Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.2164Moderately InformativeInherited
Worm Phenotype (WP)vulva morphology variant0.0001451InformativeDirect
Worm Phenotype (WP)dumpy0.000005585Highly InformativeDirect

Document: WP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)anatomical cluster0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.6285Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.9174Least InformativeInherited
Xenopus ANatomical entity (XAN)animal hemisphere0.000473InformativeDirect
Xenopus ANatomical entity (XAN)notochord0.0007325InformativeDirect
Xenopus ANatomical entity (XAN)vegetal hemisphere0.000002097Highly InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0.000000000000676InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 111 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Galactose-binding domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]