SUPERFAMILY 1.75 HMM library and genome assignments server

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Ran binding protein zinc finger-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Rubredoxin-like [ 57769] (17)
Superfamily:   Ran binding protein zinc finger-like [ 90209]
Families:   Ran binding protein zinc finger-like [ 90210] (6)


Superfamily statistics
Genomes (512) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 9,011 22,767 7
Proteins 5,790 15,109 7


Functional annotation
General category Regulation
Detailed category Other regulatory function

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.00000000009655Least InformativeDirect
Enzyme Commission (EC)Omega peptidases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.7697Least InformativeInherited
Disease Ontology (DO)nervous system cancer0.05957Moderately InformativeInherited
Disease Ontology (DO)cell type cancer0.8455Moderately InformativeInherited
Disease Ontology (DO)retinal cell cancer0.0007229Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the digestive system0.04054Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.5256Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system physiology0.5505Moderately InformativeInherited
Phenotypic Abnormality (PA)Functional abnormality of the gastrointestinal tract0.3257InformativeInherited
Phenotypic Abnormality (PA)Abnormal gastrointestinal motility0.00008411Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.02744Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.1021Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.1099Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.4582Least InformativeInherited
Mammalian Phenotype (MP)abnormal metabolism0.0123Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.0225Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal induced morbidity/mortality0.0272Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.08184Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell morphology0.09962Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal mononuclear cell morphology0.5053Moderately InformativeInherited
Mammalian Phenotype (MP)increased apoptosis0.0001109InformativeDirect
Mammalian Phenotype (MP)abnormal response to radiation0.0001293InformativeDirect
Mammalian Phenotype (MP)abnormal mature B cell morphology0.0001467InformativeDirect
Mammalian Phenotype (MP)abnormal sensitivity to induced morbidity/mortality0.01262InformativeInherited
Mammalian Phenotype (MP)increased mortality induced by ionizing radiation0.000001332Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cell nucleus morphology0.0002935Highly InformativeDirect
Mammalian Phenotype (MP)abnormal B-1 B cell number0.0009871Highly InformativeDirect
Mammalian Phenotype (MP)decreased mature B cell number0.4278Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.09441Least InformativeInherited
Enzyme Commission (EC)Lyases0.4088Least InformativeInherited
Enzyme Commission (EC)Aminoacyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0.0000002489Moderately InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0.06175Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.000000000000002009InformativeDirect
Enzyme Commission (EC)DNA-(apurinic or apyrimidinic site) lyase0.000001909Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Ran binding protein zinc finger-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 10 hidden Markov models representing the Ran binding protein zinc finger-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]