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Myosin rod fragments family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Coiled coil proteins [ 57942] (7)
Fold:   Parallel coiled-coil [ 57943] (34)
Superfamily:   Myosin rod fragments [ 90257]
Family:   Myosin rod fragments [ 90258] (2)


Family statistics
Genomes (95) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 869 2,086 3
Proteins 857 2,057 3


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)heart disease0.09028InformativeInherited
Disease Ontology (DO)dilated cardiomyopathy0.0003588Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of limbs0.01037Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.09036Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature0.1742Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.2Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.3014Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.6465Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.7167Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of connective tissue0.006222Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the thorax0.01626Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal skeletal muscle morphology0.01861Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.06184Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiovascular system physiology0.07556Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1048Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.1406Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal vascular morphology0.2363Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of movement0.4695Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.4861Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the synovia0.01147InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebral vasculature0.01668InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.0269InformativeInherited
Phenotypic Abnormality (PA)Abnormal systemic arterial morphology0.03884InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature of the limbs0.05016InformativeInherited
Phenotypic Abnormality (PA)Abnormal adipose tissue morphology0.05089InformativeInherited
Phenotypic Abnormality (PA)Abnormality of lower limb joint0.05591InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the neck0.05664InformativeInherited
Phenotypic Abnormality (PA)Abnormal nervous system electrophysiology0.05847InformativeInherited
Phenotypic Abnormality (PA)Abnormality of pelvic girdle bone morphology0.06782InformativeInherited
Phenotypic Abnormality (PA)Abnormal facial shape0.1398InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiac ventricle morphology0.186InformativeInherited
Phenotypic Abnormality (PA)Gait disturbance0.2088InformativeInherited
Phenotypic Abnormality (PA)Left ventricular dysfunction0.00007329Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal left ventricle morphology0.0002614Highly InformativeDirect
Phenotypic Abnormality (PA)Narrow face0.0004231Highly InformativeDirect
Phenotypic Abnormality (PA)Cerebral ischemia0.0007772Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of peripheral nervous system electrophysiology0.0008134Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the shoulder girdle musculature0.0008848Highly InformativeDirect
Phenotypic Abnormality (PA)Waddling gait0.0008848Highly InformativeDirect
Phenotypic Abnormality (PA)Lipodystrophy0.0009234Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the scapula0.0183Highly InformativeInherited
Phenotypic Abnormality (PA)Limb muscle weakness0.04607Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.02204Least InformativeInherited
Mammalian Phenotype (MP)abnormal muscle physiology0.3493Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.6992Moderately InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.000285InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle wall thickness0.0002902InformativeDirect
Mammalian Phenotype (MP)abnormal heart size0.09168InformativeInherited
Mammalian Phenotype (MP)enlarged heart0.0118Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell morphology variant0.06209Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.217Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.001613Moderately InformativeInherited
Worm Phenotype (WP)movement variant0.01101Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.02158Moderately InformativeInherited
Worm Phenotype (WP)locomotion variant0.06981Moderately InformativeInherited
Worm Phenotype (WP)body wall muscle sarcomere morphology variant0.00003676InformativeDirect
Worm Phenotype (WP)locomotion reduced0.002InformativeInherited
Worm Phenotype (WP)sluggish0.00005586Highly InformativeDirect
Worm Phenotype (WP)muscle system development variant0.0001908Highly InformativeDirect

Document: WP annotation of SCOP domains

Zebrafish Anatomy (ZA)

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ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.08025Least InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.046Moderately InformativeInherited
Zebrafish Anatomy (ZA)electrically active cell0.124Moderately InformativeInherited
Zebrafish Anatomy (ZA)muscle cell0.00007605InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)tissue0.2096Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.3706Least InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.03988Moderately InformativeInherited
Xenopus ANatomical entity (XAN)muscle0.01787InformativeInherited

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Myosin rod fragments domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]