SUPERFAMILY 1.75 HMM library and genome assignments server

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Diphtheria toxin, C-terminal domain alignments

These alignments are sequences aligned to the 0037312 model.

Sophisticated options are available for refining alignments:

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The numbers along the top are the segment numbers of the HMM states, and each sequence is seperately aligned to the model.
The first sequence is the seed the model was built from.
Upper case letters are aligned, lower case letters are insertions, '-' signifies a deletion and '.' is nothing.

                                                   10        20        30        40        50       
                                                    |         |         |         |         |       
gi|427728589|ref|YP_007074826.1|:4986-5036 -----------DGDTISLTNVEDGVITTIETGDGDNKIHIGSQATPTSNTGGLLDTI

                                            60        70        80        90       100       110    
                                             |         |         |         |         |         |    
gi|427728589|ref|YP_007074826.1|:4986-5036 RGR------------------------------------------------------

                                              120       130       140       150       
                                                |         |         |         |       
d1f0la1                                    SSEKIHSNEISSDSIGVLGYQKTVDHTKVNSKLSLFFEIKS..
gi|427728589|ref|YP_007074826.1|:4986-5036 -----------------------------------------vi

Statistics on alignment.   Save alignment.

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Refine alignments

Sophisticated options are available for refining alignments:

Add your sequences to the alignment:
Members of the same: including
Include all superfamily members: , or just those assigned by the selected model:
Initial T99 seed sequence: NoYes

You may enter many sequences at once using
FASTA format:

Upload a multiple sequence FASTA file:

Model: 0037312 (list models)
Initial SAMT99 seed:

Display Options:
Output in FASTA-like format: NoYes
Output column indices: NoYes
Sequence index (number) on each line: NoYes

Max number of insertions shown: (0 does not show insertions)
Characters per line:
Character to show inserts:
Maximum number of sequences:
Exclude sequences shorter than: residues

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Add alignments from genomes

Select below additional genomes you would like to see alignments for, then click on 'Re-Submit'. The genome assignments will be added to this page.

Select to display   Genome
NoYes   Corynebacterium ulcerans 0102
NoYes   Corynebacterium diphtheriae NCTC 13129
NoYes   Corynebacterium pseudotuberculosis 31
NoYes   Corynebacterium diphtheriae CDCE 8392
NoYes   Corynebacterium diphtheriae PW8
NoYes   Corynebacterium diphtheriae C7 (beta)
NoYes   Corynebacterium diphtheriae 31A
NoYes   NCBI 2017_08 genome
NoYes   STRING v9.0.5 (STRING)
NoYes   Uniprot 2018_03 genome
NoYes   PDB chains (SCOP 1.75) (PDB)
NoYes   Protein Data Bank (all PDB sequenc)
NoYes   SCOP2 SCOPe CATH ECOD (all domain sequ)
NoYes   UniProt viral sequences (Viral)
NoYes   ALL (only advised for small superfamilies)

Jump to [ Top of page · Alignments · Refine alignments · Add alignments from genomes ]