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Sema domain alignments in Gadus morhua 69_1

These alignments are sequences aligned to the 0049402 model.

Sophisticated options are available for refining alignments:


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Alignments

The numbers along the top are the segment numbers of the HMM states, and each sequence is seperately aligned to the model.
The first sequence is the seed the model was built from.
Upper case letters are aligned, lower case letters are insertions, '-' signifies a deletion and '.' is nothing.

                                                               10           20            30        
                                                                |            |             |        
d1shyb1               .................................KYQLPNFTAET...PIQNVILHE....HHIFLGATNYIYVLNEE.
ENSGMOP00000018542  ........................rryeldrsc-----------...CFGALLLDEer..GRLFVGAKNFLISLSLE.
ENSGMOP00000020178  .................temlessnlltfngla--------NSS...SYDAFLMDEer..GRLLVGAEDHIFSFDLV.
ENSGMOP00000017684  ........prvflsfkelrstgtahhfsfllns--------SDY...RILRMDEDH....DRMYVGSKDYLLSLDLH.
ENSGMOP00000020856  ......vprvtlshkelvqsgsvsvfmgasggl-----------...HSHTLLLDEek..GRLLLGARDHVYLLDPD.
ENSGMOP00000021165  ...........prvrlsfkelldtraarpfsfa-----FNTSDY...RILLMDQDQ....GRLYLGSREYLVALDMQ.
ENSGMOP00000018073  .....................vstnrssvfsgh-------QGDL...ALTAVFLDEyh..DRLFLGGKDVLYSLTLG.
ENSGMOP00000014035  ......................mtrhfsvpgll-----------...NFTSLLLSKed..NMLYLGAREALFALDLT.
ENSGMOP00000018909  ......................sakrfsvdgvs-----------...NYTSLLLSKed..DMLYVGAREALFALSLS.
ENSGMOP00000008620  ...................marfsvpgvwnyst-----------...----VTLSDhe..RVLYVGAREALFALDPN.
ENSGMOP00000020841  .....................vvfqaqqgtllq-----------...-AQTMLLDEpn..ERLYVGAKNRLLSLRLE.
ENSGMOP00000002572  .........................dlsmllpd-----------...--------Edg..RRLFVALKDNLLSTSLD.
ENSGMOP00000016637  ................................y-----------...--QALLLDEdr..GWLLVGGKDHIYLLRSD.
ENSGMOP00000010573  ..........................rftgsvq-----------...NYSTLLLDEga..GLLYVGGRGAIYALDTA.
ENSGMOP00000013126  ..............tipyhkdhgqlfheagvwn-----------...-YSTMLLREel..GLLLLGACDTIYALDLD.
ENSGMOP00000014734  ......................rfqspaavdyg-----------...---SLLLEAgg..GRLYVGARGGAFSLDAR.
ENSGMOP00000012511  ................xxvfwpaspskiqecqm-----------...---------....-----------------.
ENSGMOP00000007826  crdhiytvdtetanseeiyfskkltwksrqadv-----------...---------....-----------------.
ENSGMOP00000002600  ......................yifqlepgkvd-----------...---------....-----------------.
ENSGMOP00000013146  ...............................em-----------...HIQTVLQVN....RTLYIGARDDLYRVELD.
ENSGMOP00000008088  ..........................ttfhper--------KEW...AFNHLTVHQnt..GALYLGAVNRVYKLS-G.
ENSGMOP00000016786  ............................sfraq----------NpvsTFNHLAVDHrn..GNVYLGAVNEIYKLS-P.
ENSGMOP00000010519  ...............................ld-----------...-FQRMLRIN....HMLYIAARDHVFAIN--.
ENSGMOP00000018508  ..............................fsp--------QES...GLTHLAIHNkt..GEVYVGAINWIFKLS-S.
ENSGMOP00000002677  .................................-YTMSFFQARS...PIQNIVNNSly..QEVYIASQNVIEAVN-Q.
ENSGMOP00000007283  ..................ywkvtrekqkecayk-----------...---------....-----------------.
ENSGMOP00000020916  ......................iiltemepwif-----RFKAEGtv.DFSQLTFDPgq..NELIVGARNHLFRLSLE.
ENSGMOP00000003738  ...............................ed-----------...---------....-----------------.
ENSGMOP00000001718  ...................epvfvkiqkipdst-----------...---------....-----------------.
ENSGMOP00000019921  .............dwspsendlqqcsmkgkemv-----------...---------....-----------------.
ENSGMOP00000010771  ...............................dp-----------...---------....----------------P.
ENSGMOP00000017608  .................................NYTLPHFQTAN...PIQNIQANAyl..REVYIASQNAIEAVD-R.
ENSGMOP00000008910  .................................-----------...---------....---YLGGTDFVLKID--.
ENSGMOP00000019621  ................................e-----SFASPN...RTNNFVVDKvs..RNVYLAAVNTIYQLN-G.
ENSGMOP00000016677  .................................-----------...---------....-----------------.
ENSGMOP00000009540  .................................------FTTET...PINNVVQDPgs..GRIYLGAVNAIFQLG-P.
ENSGMOP00000009360  ................................e-----------...---------....-----------------.
ENSGMOP00000019357  ....................ydssdrglvhfsq---------PNvrnTTTLLLSDDg...STLYVGARNNILSLDVS.
ENSGMOP00000008307  ..............................rke----------W...ALNHLTVHQst..GALYVGAVNRIYKLS-A.
ENSGMOP00000020848  ........................xdvflmstk-----------...---------....-----------------.
ENSGMOP00000016524  .................................-----------...---------....-----------------.
ENSGMOP00000009068  .......................psgnesqhrl-----------...DFQLMTKIQ....DTLFIAGRDQVYLVS--.
ENSGMOP00000002576  ..............................pll-----------...-IQRVLQVN....RTLYIGARDDLFRVELD.
ENSGMOP00000002576  ................................x-----------...---------....-----------------.
ENSGMOP00000020049  ................................s-----FSRNDT...LFEHLALHPdpsvGRVYVGGRDRLYQLD-R.
ENSGMOP00000011087  .................................-----------...---------....-----------------.
ENSGMOP00000020848  ..............................gpf-----------...---------....-----------------.
ENSGMOP00000000020  ...............................rg-----------...---------....-----------------.
ENSGMOP00000009026  .............................esnv-----------...---------....-----------------.
ENSGMOP00000001784  ................................k-----------...---------....-----------------.
ENSGMOP00000000020  ................................t-------RNDT...DFQHLLLHPdpavGTVYVGARDHLFQLD-Gl
ENSGMOP00000020049  ...............................xn-----------...---------....-----------------.
ENSGMOP00000008307  ...............................pv-----------...---------....-----------------.
ENSGMOP00000001784  ................................a-----------...---------....-----------------.
ENSGMOP00000009026  ...............................ge-----------...---------....-----------------.
ENSGMOP00000020848  .........vprlklsykemlqsnnlvtfdgla--------NSS...AYHTFLLDEek..GRLVVGAKDHIFSFNLL.
ENSGMOP00000002600  .............................lnts---------DY...RILRMDEDH....DRMYVGSKDHILSLDLH.


                           40         50        60           70        80         90        100     
                            |          |         |            |         |          |          |     
d1shyb1               .DL...QKVAEYKTG.PVLEHPDCFPCQD.CSSKAN.LS.GGVWKDNINMALVVDTYYD.DQLISCGS.VNRGTCQRH
ENSGMOP00000018542  .NI...GKQEHKIYW.PAPVNWREEC---.-NWAGK.E-.INVDCVNYVKILHHYN--R.THLFACGTgAFHPTCAFV
ENSGMOP00000020178  .NI...NRDHKQIAW.PATPSKRDECKWA.GKDYVK.E-.----CSNYVRVLQPFN--H.THLYICGTgAFHPICSYL
ENSGMOP00000017684  .DI...NKEPLIIHW.PVAPQRKTECVLS.-GKD--.--.TNGECGNFIRLIEPWN--R.THLYVCGTgAYNPICTYV
ENSGMOP00000020856  .NL...SRAPRKRVK.-------------.MCKLAG.KN.VNLECANFVRVLHNYN--H.THVYACGTgAFHPTCAFI
ENSGMOP00000021165  .NV...NKEPLIIHW.PASAKRKGEC---.-QMTGK.G-.RQGECANFVRLIEPWN--R.THLYTCGTgAYQPICTFI
ENSGMOP00000018073  .PAa..TESKEIHWP.PLPGNRDD-----.--CIQRgKE.PQTDCANFVRLLKPFN--R.THLLACGTgAFQPICSYI
ENSGMOP00000014035  .DI...TTPRLQRNI.--TWNTPASKRDE.CSFKGK.D-.LQKDCFNYIKILLRYN--S.THLYVCGTyAFSPTCAYI
ENSGMOP00000018909  .DIskdKLQKNMTWGtPVGKREECSF---.-KGK--.-N.LETDCFNYIKILLRLN--S.THLYVCGTyAFSPICAYI
ENSGMOP00000008620  .DI...SRQRRPQIE.WPAPQDKKKE---.-CASKG.KN.NQTECFNYIRFLQSYN--S.THLYTCGTyAYQPKCTYV
ENSGMOP00000020841  .HI...NRDHKEI--.-RWASSE---SQI.EECLMK.GR.EKPECANYIKVLQQYN--S.THLLACGTgAFNPTCGLL
ENSGMOP00000002572  .DI...TQNPRKLYW.PA--SPDRVQE--.-CLMAG.KH.PETECGNFLRVLQPYN--Q.THLYVCGTgAFNPRCVFI
ENSGMOP00000016637  .SL...DLPTRTIYW.PA--SPDHVEHCR.QAGKSL.E-.--MECANFVRVLQPFN--K.THVYVCGTgAYDPQCSYL
ENSGMOP00000010573  .NI...SAPANATID.WEASAEQK-----.KQCLNK.GKdNQTECYNHIRFLEHYN--S.THLYVCGThAFRPLCAYI
ENSGMOP00000013126  .NI...SDKKAVKWEvPEAKQTECKN---.---KGK.D-.AEIHCKNYIRVLHTLS--D.GRMYVCGTnAFDPECDLM
ENSGMOP00000014734  .DI...SANTTLAIQ.WETSQEKKQQCLA.----KG.RD.NKTECFNHIRFLQRFN--S.THLYMCGTyAFSPLCVYV
ENSGMOP00000012511  .--...---------.-------------.----AG.KD.PTHGCGNFIRVLQPYN--R.THLFMCGSgAYSPVCIYV
ENSGMOP00000007826  .--...---------.------------D.-TCRMK.GK.HKDECHNFIKVLLKQN--N.DTLFVCGTnAFNPSCRSY
ENSGMOP00000002600  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000013146  .NM...VGDEMFYSK.XXXXXXXXXXXX-.--XXQM.KD.NEGECRNYIKVLLSHH---.DGLFVCGTnAFNPLCANY
ENSGMOP00000008088  .NL...TLLVSHDTG.PEDDNKACYPPLI.VQPCSE.PL.--VATNNVNKLLLVDY-SQ.NRLLACGS.LYQGVCKLL
ENSGMOP00000016786  .EL...KYQMSHQTG.PDEDNRKCYPPRI.VQTCSE.PL.--ALTNNVNKMLLMDY-KE.NRLLACGS.LYQGICKIL
ENSGMOP00000010519  .-L...PASSERIV-.PMQKLTWKTKDVE.-KCTVR.GK.NSDECYNYIKVLVPRN--D.ETLFACGTnAFNPACRNY
ENSGMOP00000018508  .NL...TKLRNHMTG.SVVDNEKCYPPPS.VQSCPH.EL.--SQTPNVNKLLLIDY-AQ.NRLIACGS.TSQGICQFL
ENSGMOP00000002677  .SL...EKVWELPTG.PV-GSPECEICD-.-MCDVD.KD.PNYLEDTDNQVLLLDT-LF.MYLYSCGS.SQYGVCYFH
ENSGMOP00000007283  .--...---------.-------------.-----G.KQ.SEVECRNYIQTLHPVN--Q.TTMYVCGTnAFSPVCDYM
ENSGMOP00000020916  .DL...TLIQGAEW-.------HCDEFTK.GACFSR.GK.SEEECQNYIRVLLVNG---.NRLFTCGTnAFTPICTNR
ENSGMOP00000003738  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000001718  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000019921  .--...---------.-------------.------.--.--MDCPNFIRVLQFLN--T.THMYACGTyAFSPRCTYM
ENSGMOP00000010771  .NL...TELRSHTTG.PVEDNAKCTPPSV.RSCAHR.L-.--ESMDNVNKLLLVDY-SG.NRLVACGS.IWQGVCQFL
ENSGMOP00000017608  .DL...KRIWEVRTG.PV-GPDDCHTCGP.CDAATT.P-.PATPVDTDNKVLLLDRRAPsPYLYYCGS.TRQGVCAFL
ENSGMOP00000008910  .--...---------.-VDSNYVMETFQL.NKSANE.VC.SQGPCRNVITVIEEFQ---.DSLFVCGTnGYKPQCWKL
ENSGMOP00000019621  .TL...SLEVEKRTG.PVQDNLLCHAPQL.-PQAPC.EH.PKSLTDNYNKLLELDP-EQ.GVVVVCGS.VYQGFCELR
ENSGMOP00000016677  .--...---------.-------------.------.--.---DCNNYIRLLEILD--D.DRIYVCGTyAFDPQCAFL
ENSGMOP00000009540  .AL...NQEARAETG.PKLDSRTCTPPP-.-SACQD.T-.--KLMPNLNKLLLVHP-AN.GSLIVCGS.RYKGICSLL
ENSGMOP00000009360  .--...---------.-------------.------.--.----CDNFITVVQKVN---.DTFVVCGTnAGSPKCWLL
ENSGMOP00000019357  .DP...EVITLKE--.---EREDIEA---.-CSKKQ.KS.AEVDCPNFIRVLQPMN--S.THLYACGSyAYNPHDALL
ENSGMOP00000008307  .NL...TLLVSHDTG.PEYDNKACYPPLI.VQPCSE.PL.--ASTDNVNKLLLVDY-SH.NRLLACGS.LYQGVCKLM
ENSGMOP00000020848  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000016524  .--...---------.-------------.------.--.-------------------.-TLVECGS.VFRGICSLR
ENSGMOP00000009068  .-L...RESYRNEII.PYRKLTWRSGPADrEMCAVK.GK.HRDECHNFIKVLVPRN--D.DLVFICGTnGFNPMCRYY
ENSGMOP00000002576  .NV...AGEEMFYSK.K--RTWESNKNDI.RICRMK.GK.HEDECRNFMKVLLSKA--G.GGLFICGTnAFNPMCANY
ENSGMOP00000002576  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000020049  .AL...ALELQDDTG.PVTDSRECLPPVT.QGNCPQ.A-.--RLTPNHNKLLLVDP-YS.MELIACGS.VNQGICQKR
ENSGMOP00000011087  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000020848  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000000020  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000009026  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000001784  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000000020  eGL...RLQQEETTG.PVKDSKDCLPPVT.EANCPQ.A-.--RWTSNHNQLLLVDP-WA.AELITCGS.VHQGTCQKR
ENSGMOP00000020049  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000008307  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000001784  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000009026  .--...---------.-------------.------.--.-------------------.--------.---------
ENSGMOP00000020848  .NI...SKDYSQIAW.P------------.------.--.-------------------.--------.---------
ENSGMOP00000002600  .DI...NKAPLIIHW.PVSQQ--------.------.--.-------------------.--------.---------


                           110                                                   120       130      
                             |                                                     |         |      
d1shyb1               VF...PHNHTA.......................................DIQSEV.....HCIFSPQIEEPSQCPDC
ENSGMOP00000018542  EV...GQKFEDgvfridptk..............................VEDGKG.....RSPYDPRHTAASVLIG-
ENSGMOP00000020178  EM...GKRAEDnifrlash...............................FENGRG.....KSPYDPKMLSSSLMID-
ENSGMOP00000017684  DR...GRRSQGslhlqnpqsgsrtnraadfsstagpveaqqyifrlepgkVDSGKG.....KCPYDPKLNSVSALIN-
ENSGMOP00000020856  EL...TGHRESgvfqllpss..............................FESGRL.....KCPFDPRQPFTSVLTD-
ENSGMOP00000021165  NR...GWRAEDylfrlvpgy..............................ADSGKG.....KCSYDPNQENIAVLID-
ENSGMOP00000018073  HV...GYRGEXxxhvftmdptn............................VENGRG.....KVPHDPSLPFASTFNG-
ENSGMOP00000014035  NA...TDFSLVrgsggeiv...............................TEDGRS.....RCPFNPEYKSTAIMAD-
ENSGMOP00000018909  NT...STFSLErddsgevl...............................MEDGRS.....RCPFNPEYKSTAIIVD-
ENSGMOP00000008620  IA...ANFTLSpap....................................LEDGRG.....KCPYDPAKGHTGLIVD-
ENSGMOP00000020841  AV...GTKATDrlfslaees..............................VESGRG.....RCPYDPNSLCTSTLYR-
ENSGMOP00000002572  AT...SLFLKSdhqslsygq..............................TECGKG.....KCPYDPHQRTASAVVD-
ENSGMOP00000016637  HL...GDSSQDpvfllspt...............................VESGRG.....RCPFSPSEPFTARLTD-
ENSGMOP00000010573  DT...EHFNFSsg.....................................LEEGRD.....RCPYDPAKGFTGLLIE-
ENSGMOP00000013126  SY...KDGNLIlekevs.................................IGDGKG.....KCPFDPFQTYASIMVD-
ENSGMOP00000014734  EE...EPFVMS.......................................SQPEEGke...KCPYGPATGYTGLIVE-
ENSGMOP00000012511  NR...GRRPEEqvfhidrq...............................TESGKG.....RCSFNPQVNTVSVMIN-
ENSGMOP00000007826  KM...DTLEPQ.......................................GEEISGma...RCPYDAKHANVALFAD-
ENSGMOP00000002600  --...------.......................................--SGKG.....KCSYDPKLNSVSALIN-
ENSGMOP00000013146  TR...DSLEMA.......................................GESVSGma...RCPYDPRHANVAVFAE-
ENSGMOP00000008088  RL...DDLFIL.......................................VEPSHK.....KEHYLSSVN-------Q
ENSGMOP00000016786  RL...DDLFKL.......................................GEPFHK.....KEHYLSGVN-------E
ENSGMOP00000010519  KM...ATLEQD.......................................GEEMLGqa...RCPFESRQSN-------
ENSGMOP00000018508  RL...DDLFKL.......................................GEPHHR.....KEHYLSSVA-------E
ENSGMOP00000002677  QL...NTHGAP.......................................PSPSK-.....-CLFRKESNSAAYCPDC
ENSGMOP00000007283  T-...QLVLHG.......................................QQEEGG.....KCPFDPFQRYSSLMVG-
ENSGMOP00000020916  TL...TNLTEI.......................................HDQISGma...RCPYNPRHNSTALITS-
ENSGMOP00000003738  --...------.......................................---GRG.....KCAFDPSHSVTTVMVD-
ENSGMOP00000001718  --...------.......................................------.....-----------------
ENSGMOP00000019921  ENltmTSQSSK.......................................PEEGRG.....RCPYDPYQRNTAITVD-
ENSGMOP00000010771  RL...EDLFKL.......................................GEPHHR.....KEHYLSGAR-------E
ENSGMOP00000017608  DI...SELSPV.......................................-----S.....HCLFKEQDNTETYCPDC
ENSGMOP00000008910  YS...QVGNRS.......................................SEIVESydgtgISPYVYTQNRLSLTVE-
ENSGMOP00000019621  KL...ENISEI.......................................AVEFPPqge..KTVFPSMLN--IAANHP
ENSGMOP00000016677  XX...XXXXXXxxeeqevr...............................METGKG.....KCFEPSQHYTAVMA---
ENSGMOP00000009540  NL...TNVEQQ.......................................LYYSD-.....----SKGERTYVASIED
ENSGMOP00000009360  GS...GLIGSP.......................................SDISP-.....--P-YPSQKAISLATD-
ENSGMOP00000019357  DI...QTLTLT.......................................SVSAGAkg...RCPFNPFERNTAITL--
ENSGMOP00000008307  RL...GDLFIL.......................................VEPTHK.....KEHYLSSDN-------H
ENSGMOP00000020848  --...------.......................................------.....-----------------
ENSGMOP00000016524  NL...SRVEHL.......................................LYFSD-.....----TNGEKSYVASAEE
ENSGMOP00000009068  RL...DNLEFD.......................................GEEISGla...RCPFDSKQTNVALFAD-
ENSGMOP00000002576  TX...XXXXXX.......................................XXXXXX.....XXXXXX-----------
ENSGMOP00000002576  --...------.......................................------.....-----------------
ENSGMOP00000020049  SL...VNISAV.......................................LFSAQ-.....----RPVDTQYVAANDP
ENSGMOP00000011087  --...------.......................................------.....-----------------
ENSGMOP00000020848  --...------.......................................IENGRG.....KSPYDPKLFTASMLID-
ENSGMOP00000000020  --...------.......................................------.....-----------------
ENSGMOP00000009026  --...------.......................................------.....-----------------
ENSGMOP00000001784  --...------.......................................------.....-----------------
ENSGMOP00000000020  SL...TSVSQV.......................................LFSSE-.....-----------------
ENSGMOP00000020049  --...------.......................................------.....-----------------
ENSGMOP00000008307  --...------.......................................------.....-----------------
ENSGMOP00000001784  --...------.......................................------.....-----------------
ENSGMOP00000009026  --...------.......................................------.....-----------------
ENSGMOP00000020848  --...------.......................................------.....-----------------
ENSGMOP00000002600  --...------.......................................------.....-----------------


                       140          150       160          170                    180           190 
                         |            |         |            |                      |             | 
d1shyb1               VVSALGAKVLS...SVKDRFINFFVGNTI...NSSYFPDHPL............HSISVR.RL.KETK...DGFMFL.
ENSGMOP00000018542  -----------...------DELYAGVAT...DLMGRDFTIF............R--SLG.KA.IRTE...------.
ENSGMOP00000020178  -----------...------GELYSGTSA...DFMGRDFAIF............RTLGDQ.HP.IRTE...------.
ENSGMOP00000017684  -----------...------GELYAGVYI...DFMGTDSAIF............RTLGKQ.TA.MRTD...------.
ENSGMOP00000020856  -----------...------QYLYAGTAS...DFLGKDTTFT............RSLGPP.PD.QNY-...------.
ENSGMOP00000021165  -----------...------GNLYAGVHI...DFMSTDAALF............RTMGGR.TA.IRTE...------.
ENSGMOP00000018073  -----------...------GELYAGLTA...DFLGRDSVIF............RSMGGR.ST.MRTE...TDQKLL.
ENSGMOP00000014035  -----------...------GELYAGTVS...NFQGNEPIIY............KSLGHG.TA.LKTE...NSLNWL.
ENSGMOP00000018909  -----------...------GELYAGTVS...NFQGNEPVIY............KSLGHG.TA.LKTE...NSLNWL.
ENSGMOP00000008620  -----------...------EELYSATLF...NFLGTEAVIL............RNLGHQ.HYsMKSD...DLPAWL.
ENSGMOP00000020841  -----------...------GELYIGVYT...DYWENDGALC............RLNSQT.YT.RTE-...------.
ENSGMOP00000002572  -----------...------GELYAGITS...DFMSRDSAFF............RSLGNR.RV.MRTE...------.
ENSGMOP00000016637  -----------...------GELYSGTSV...DFMGANAAIF............R-----.--.----...TAVQAN.
ENSGMOP00000010573  -----------...------GEMFTASQY...EFRSSPDVRR............-NFPLP.AL.RTEEap.TRWLLA.
ENSGMOP00000013126  -----------...------DNLYSATSM...NFLGSEPVVM............RSSSIS.IR.TEFK...SSWL--.
ENSGMOP00000014734  -----------...------QQMYSAARY...EFRSFPDLRL............N-GPPL.TL.KTED...APIRWL.
ENSGMOP00000012511  -----------...------QELFSGVYI...DFMATDAAIF............RSLTRR.NA.VRSD...------.
ENSGMOP00000007826  -----------...------GKLYSATVT...DFLAIDAVIY............RSLGDS.PT.LRT-...------.
ENSGMOP00000002600  -----------...------GELYAGVYI...DFMGTDSAIF............RTLGKQ.TA.MRTD...------.
ENSGMOP00000013146  -----------...------GSLFTGTVT...DFLAIDAVIY............RSLGDS.PA.LRT-...------.
ENSGMOP00000008088  TGTMYGVIVPS...--QGQDGTLFIGTAV...DGKQDY---F............PTISSR.KL.PRDP...ESSAMLd
ENSGMOP00000016786  SGSVFGVIVSY...-SNASPDMLFVATAV...DGKPEY---F............PTISSR.KL.ARNSeadSMFAYV.
ENSGMOP00000010519  -----------...------VGLFAGRLG...DSTLTGPSTS............------.--.----...-----L.
ENSGMOP00000018508  SGTMSGVIISS...-PHNPTSKLFIGTPI...DGKSEY---F............PTLSSR.KL.MENEenaDMFSFV.
ENSGMOP00000002677  LASGLGTKVTL...VEEGQTVYFFVAVTV...NDSVTQRYGR............KSLSVR.RP.LATE...DGFY--.
ENSGMOP00000007283  -----------...------SDLYSATFI...NFLGSEPVVL............RSSQTA.VR.TEFK...SSWLNE.
ENSGMOP00000020916  -----------...-----AGELYAATAM...DFSGRDPAIY............RSLGGM.PP.LRTA...------.
ENSGMOP00000003738  -----------...------GELYSGTVY...NFLGSEPIIS............RYSPQQ.AL.LRTE...YSTS--.
ENSGMOP00000001718  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000019921  -----------...------GELYTATVA...DYRGNRPVIS............RHLSPV.DL.KLD-...DTLGWL.
ENSGMOP00000010771  ADGMAGVVIEN...--GKGSSHLFIGAAI...DGKSEY---F............PTLSSR.KL.VEDEesvNMFSLV.
ENSGMOP00000017608  LASPLGTRVSA...VEQGQTTLFFVANSV...DEELASRWPR............RSLSVL.RP.LSTE...DGFH--.
ENSGMOP00000008910  -----------...------GDLYAAAPL...EYDGSSLQFR............RKAGSR.TN.VWMY...DNWVSE.
ENSGMOP00000019621  NASTVGLVFRS...--HGGNTRLLVGATY...TGAGTAFFPKnhskedlrfentPEIAIR.SL.NIKD...LSRLFTy
ENSGMOP00000016677  -----------...---------YTAATS...NFLGTMFDIS............RATGPEqGR.IRTE...RSINWL.
ENSGMOP00000009540  NVNVVGVMSTYhlrDIQDEFSVFVVGKGY...GRMDSTKL--............--ISTR.IL.EDRR...EWVVFE.
ENSGMOP00000009360  -----------...-----GGSLYSALSS...VGGHTGSI-R............RTFGSQ.KL.LKAE...NVWLLN.
ENSGMOP00000019357  -----------...-----------GTPQ...QYKCSPFTTF............QSNSLR.SL.RRTS...EWGAIS.
ENSGMOP00000008307  TGTMYGVVVPS...--PGQDATLYVGTAV...GGKQDY---F............PTVSSR.KL.PRDP...ESSAMLd
ENSGMOP00000020848  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000016524  AVSVVGVMSFYn..DSSSNFSVFLVGKGY...GSHDSTKL--............--ISTR.IL.KPHG...DWVVFD.
ENSGMOP00000009068  -----------...------GKLYSATVA...DFQASDAVIY............RSMGDG.SA.LRT-...------.
ENSGMOP00000002576  -----XXXXXX...XXXXXXGNLFTATVT...DFLAIDAVIY............RSLGDH.PA.LRT-...------.
ENSGMOP00000002576  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000020049  EVSTVGLVVRS...-RPERQPVLYVGRGY...TSSHPP----............--ISTR.NL.QQEP...----VF.
ENSGMOP00000011087  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000020848  -----------...------GELYSGTSA...DFMGRDFAIF............RTLGKH.HP.IRTE...------.
ENSGMOP00000000020  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000009026  -----------...------IHFFAGNSEipgDGRAGGAAAP............HTMSVR.KM.KTSQ...NGFTFF.
ENSGMOP00000001784  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000000020  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000020049  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000008307  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000001784  --TMSGVVVPPsp.FGGGGGGKFFVGTPI...EGKSEY---F............PTLSSR.RL.TGNEedaDMFSFV.
ENSGMOP00000009026  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000020848  -----------...---------------...----------............------.--.----...------.
ENSGMOP00000002600  -----------...---------------...----------............------.--.----...------.


                                 200              210                         220       230         
                                   |                |                           |         |         
d1shyb1               ....TDQSYIDVLP.......EFRDSYPIKYV.......HAF...........ESNNFIYFLTVQRETL.........
ENSGMOP00000018542  ....--------QH.......DSRWLNEPKFV.......GSFwvpesen....PDDDKIFFFFRETAVEaqg......
ENSGMOP00000020178  ....--------QH.......DSRWLNDPRFV.......GVNlvpesdn....PEDDKIFLFFKENAMDgeh......
ENSGMOP00000017684  ....--------QY.......NSRWLNDPTFI.......HAHlipdstq....KNDDKLYFFFREKSSEmg.......
ENSGMOP00000020856  ....----IRTEIS.......EDYWINEASFI.......SAHpmsdthn....PDDDKIYFFFREVSREg........
ENSGMOP00000021165  ....--------QY.......DSRWLNEPVFLkiqqipdSAE...........RNDNKLYFFFREKSLDsvsg.....
ENSGMOP00000018073  ....HDPRFIAA--.......-----------.......--Hvvpdsdd....RDDDKVYFFFTEKAMEsgd......
ENSGMOP00000014035  ....QEPSFVGSAYiq.....ESLPKGNP---.......--V...........GDDDKIYFFFSEAGKEfdf......
ENSGMOP00000018909  ....QDPVFVGSAYie.....ESQPTGNP---.......--V...........GDDDKIYFFFSEAGKEfdf......
ENSGMOP00000008620  ....KEPDFVGSSLvr.....ESLGSK-----.......--E...........GDDDKIYFFFSERPTEdrnc.....
ENSGMOP00000020841  ....--------RD.......DRQQLNQPKFI.......KSVvipdndd....PEDDKVYFFFTEREQNpeg......
ENSGMOP00000002572  ....--------QY.......DSTWLHDAQFV.......RVAplsetdn....PEDDKVYVFFTERAQEaega.....
ENSGMOP00000016637  ....SQDYIRTEAY.......DDHWLNEPEFV.......GSFsipdths....PDDDKVYFFYREKAVEggq......
ENSGMOP00000010573  ....SEADFVGSAL.......LKEHVN-----.......SSI...........GDDDKIYFFFTERSQEltay.....
ENSGMOP00000013126  ....NEPNFISMAQvp.....ESKD-------.......NSE...........GDDDKVYLFFNEAALEyds......
ENSGMOP00000014734  ....NDADFVGSALvr.....ESVDSF-----.......--E...........GDDDKIYFFFTEGSEEqtgg.....
ENSGMOP00000012511  ....--------QH.......NSKWLSEPVFI.......DAQlipdgsd....PNDAKLYFFLRERLTDhsg......
ENSGMOP00000007826  ....-------VKH.......DSKWLKEPNFV.......QAV...........NYGDFIYFFFREIAMEynt......
ENSGMOP00000002600  ....--------QY.......NSRWLNDPSFV.......RVQlipdsae....RNDDKLYFFFREKSSEmg.......
ENSGMOP00000013146  ....-------VKH.......DSKWFREPFFV.......SAV...........EWGPHIYFFFREMAMEfhh......
ENSGMOP00000008088  ..yeLHTDFVSSLIkipsdtlALVSHFDIYYV.......YGF...........ASGNFVYFLTVQPETPensmssggs
ENSGMOP00000016786  ....FHDEFVASMIkipsdtfTVIPDFDIYYI.......YGF...........ASGNFVYFLTLQPEMGggpstgsss
ENSGMOP00000010519  ....LMFLIVCIXX.......PPSSSPEPHFL.......HAI...........EYGNYVYFFFSEIAVEytt......
ENSGMOP00000018508  ....YQDEFVSSQLkipsdtlSKFPAFDIYYV.......YSF...........SSEHFVYYLTMQLDTQltspdas..
ENSGMOP00000002677  ....RDVRGLTVLP.......GLRRTYGIRYV.......YSF...........FTQEFVYFLSVQRESPdq.......
ENSGMOP00000007283  ....PTFVYMDHIP.......ESVDS------.......-AD...........GDDDKVYLFFSEKAMEydf......
ENSGMOP00000020916  ....--------QYn......SKWLNAEPNFV.......SSY...........DIGNFTYFFFRENAVEhd.......
ENSGMOP00000003738  ....----------.......---WLNEPSFV.......FADviregggpa..GEDDKIYYFFTEVSVEyef......
ENSGMOP00000001718  ....----------.......-----------.......--Q...........ANDDKLYFFFREKSLDstgg.....
ENSGMOP00000019921  ....EDPTFVSSSF.......-----------.......--I...........PSEEKIYFFFSEVGREydf......
ENSGMOP00000010771  ....YQDEFVSSQIkipsdtlSLYPAFDIYYV.......YGF...........SSRSHVYFLTLQLDIQltqmdaa..
ENSGMOP00000017608  ....MAMQGLTVLP.......PLRASYRVDYV.......YTF...........ATAEHVYFLSVQRENPek.......
ENSGMOP00000008910  ....PTFVAASWVR.......RK---------.......-ED...........RENEKIYIFFREKNSDssp......
ENSGMOP00000019621  dinpSEDNVFKIKQ.......EVKTKNKLNFV.......HAF...........VQKTYSYIAINNDAKTgh.......
ENSGMOP00000016677  ....NDPEFVS---.......-----------.......-ASfiqqdptseplGDDDKLYFFFTEVAKEyem......
ENSGMOP00000009540  ....SIVEASAVQTa......PFAPKHQHDFR.......HAF...........KDDGFVYFLFSRTRDG.........
ENSGMOP00000009360  ....PQFAGAAIIP.......-----------.......SSL...........KYKEEIYFFFSEFNKTarv......
ENSGMOP00000019357  ....PEPTFVSSAF.......-----------.......--D...........QKEGKLYFFFSEVLKEfnc......
ENSGMOP00000008307  ..yeLHTDFVSSLIkipsdtlALVPRFDIYYV.......YGF...........SSGPFVYFLTVQPETPpesgtpagg
ENSGMOP00000020848  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000016524  ....SIIEASSVQAs......SFVLRYLHDFR.......FVF...........KDGIYVYFLFSRTLGV.........
ENSGMOP00000009068  ....-----IKYDS.......NGLKVREPHFL.......HAV...........EYGNYVYFFYREIAVE.........
ENSGMOP00000002576  ....-------VKH.......DSKWFREPYFV.......SAV...........EWGPHIYFFFREMAME.........
ENSGMOP00000002576  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000020049  ....SYEETAKLAVa......G----------.......---...........----------------.........
ENSGMOP00000011087  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000020848  ....--------QH.......DSRWLNEPRFV.......SVHlipesdn....PEDDKIYLFFRESAIDgeh......
ENSGMOP00000000020  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000009026  ....SHRSYIDLIP.......ALRGNYFLRYV.......YSF...........HSGPFTYFLTVQRAGR.........
ENSGMOP00000001784  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000000020  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000020049  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000008307  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000001784  ....YQDEFVSSQLkipsdtlSKFPAFDIYYV.......HGF...........HSEQFVYYVTLQLDT-.........
ENSGMOP00000009026  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000020848  ....----------.......-----------.......---...........----------------.........
ENSGMOP00000002600  ....----------.......-----------.......---...........----------------.........


                               240                    250       260             270        280      
                                 |                      |         |               |          |      
d1shyb1               ..DAQTFHTRIIRFCSINSG.............LHSYMEMPLECILTELVPRGS......TKKE.VFNILQAAYVSKP
ENSGMOP00000018542  ..LGKSSYSRIGQLCRNDMGgqrslvnk.....WTTFLKTRLICSVPGADGS--......--DT.YFDELRDVFLLQ-
ENSGMOP00000020178  ..SGKATIARIGQLCKNDMGghrslvnk.....WTTFLKARLMCSVPGANGI--......--DT.HFDELQDVFLMS-
ENSGMOP00000017684  ..QSPMAQSRIGRICLNDDGghcclvnk.....WSTFLKARLICSVPGADGI--......--ET.HFDELRDVYIQP-
ENSGMOP00000020856  ..KDKSILSRVARVCKNDVGglrsltnk.....WTTFLKARLVCSIPGPDGV--......--DT.HFDELQDIFMLP-
ENSGMOP00000021165  ..ASPSVLARVGRVCLNDEGgqkslvnr.....WTTFLKARLICSVLGEDGV--......--ET.AFDELRDVFIQP-
ENSGMOP00000018073  ..REGAIHTRVGRVCANDVGgqrvlvnk.....WSTFIKARLVCSVPGPHGI--......--DT.HFNQLEDIFVLR-
ENSGMOP00000014035  ..FDNTIVSRIARVCKGDKGgervlqkk.....WTTFLKAQLLCSLPDD-----......--GF.PFNIIQDMFVLTP
ENSGMOP00000018909  ..FDNTIVSRIARVCKGDKGgervlqkk.....WTTFLKAQLLCSLPDD-----......--GF.PFNIIQDMFVLKP
ENSGMOP00000008620  ..YAERTMARVARVCKGDLGgkrtlqkk.....WTTFQKARLVCSLPER-----......--HV.AFNNLRATFTLP-
ENSGMOP00000020841  ..ETKAVYTRVGRVCANDQGgrrmlvnr.....WSSFLKTRLICSVAGANGI--......--DT.HFDELEDIFVLQ-
ENSGMOP00000002572  ..AGKVLYSRVARVCKNDIGgqrslvnk.....WSTFQKARLVCSVPGADGL--......--QT.HFNQLQDIFILN-
ENSGMOP00000016637  ..WNKMIHSRVARVCKNDVGgkrslinr.....WTTFQKARLVCSIPGPSGM--......--DT.VFDELQDIFLLE-
ENSGMOP00000010573  ..PSQTRVARVARVCKSDWGgqrtlqkr.....WTSFLKARMVCSVPDY-----......--EL.HLNIMRSVFVLQ-
ENSGMOP00000013126  ..YSKLMVSRVARVCKGDLGgqrtlqkk.....WTSFLKARLDCPVLES-----......--KL.-PFTIQDTFLLCE
ENSGMOP00000014734  ..IAHGRVARVARICKGDRGglltlqkr.....WTTFLKARLVCSQPEY-----......--DF.HFNVLRSVFVLR-
ENSGMOP00000012511  ..NTKSLHTLLARVCPNDVGgqrslvnk.....WTTFQKARMVCSVQEEDGT--......--ET.YFDELESVFLLE-
ENSGMOP00000007826  ..MGKVVFPRVARVCKNDRGgsqrvlekq....WTSFLKTRLNCSIPGDS----......--HF.YFNILQAVTNVI-
ENSGMOP00000002600  ..QSPVTQSRIGRICLNDDGghcclvnk.....WSTFLKARLICSVPGADGM--......--ET.HFDELRDVYIQP-
ENSGMOP00000013146  ..LEKVMVSRVARVCKTDLGgsqrvlekq....WTSYLKARLNCSVPGDS----......--HF.YFNLLHATSGVL-
ENSGMOP00000008088  .sSDLFYTSRIVRLCKDDRK.............FHSYVSLPVGCVKN-------......--GV.EYRLLQAAYLGKP
ENSGMOP00000016786  ggREQVYTSKIVRLCKDDTA.............FNSYVEVPLGCVSG-------......--NV.EYRLLQAAYLAKA
ENSGMOP00000010519  ..LGKVVFSRVARVCKNDNGgsprvlery....WTSFLKARLNCSVPGDS----......--FF.YFDVLQSLTNVL-
ENSGMOP00000018508  ..GEQFFTSKIVRLCVDDPK.............FYSYVEFPIGCTKD-------......--GV.EYRLVQDAYLARP
ENSGMOP00000002677  ..ESSPFQTRLGRLPRNEWE.............MKRYREVVLECRFEPKRRRRNvasep.YRDV.VYNVVQAAHFGRA
ENSGMOP00000007283  ..YSKLTVSRVARVCKEDMGgqrtlqrk.....WTSFVKARLDCSLPE------......--PS.LPPIVQDVFLLK-
ENSGMOP00000020916  ..CGRTVFSRAGRVCKNDIGgrflledt.....WTTFMKARLNCSRPGEI----......--PF.NYXXXXXXXXXXX
ENSGMOP00000003738  ..FGKLFIPRVARVCKGDLGgqrtlqkk.....WTSFLKAKLVCSMPEL-----......--NF.VFNVVHDVFVLE-
ENSGMOP00000001718  ..NNPIMVSRVGRVCLNDDGgqrslvnk.....WTTFLKARLVCSVTGGDGV--......--ET.HFDELRDVFILP-
ENSGMOP00000019921  ..IDKFIVSRVAQICTSDVGgqrtlqrr.....WTTFAKAQLLCQASS------......--EL.PYNVVQDITDLPP
ENSGMOP00000010771  ..GEKFFTSKIVRMCSNDTE.............FYSYVEFPLGCTKE-------......--GV.EYRLVQAAYKQKP
ENSGMOP00000017608  ..SGSPLQTRLGRLPLMNSE.............AWMYREVVLECRFDPKRRRRKrrggeeQHRV.VFNGLQAAHYGPV
ENSGMOP00000008910  ..EADPWVTRVARVCKVDEGgskrffqnt....WTSFLKARLVCGYPKE-----......--SL.YFNHLLDVYVLHA
ENSGMOP00000019621  ..KESQPNSILARICLDTDQprksnsgpesrklTESYIQMPLQCGLS-------......--GN.IYNRLLSVYPVDI
ENSGMOP00000016677  ..YTKVKVPRVARVCKSDVGgmktlqrr.....WTTFLKAQLVCEDRPS-----......--GQ.RYNVLTDVFTLRR
ENSGMOP00000009540  ..TDNKNLTYVSRICESDNN.............YYSHTELMLSCGPGNR-----......----.-YNKVQAAYVAIP
ENSGMOP00000009360  ..DEEPYRARIGRICTVDEGgikplltds....WTTFMKARMMCGSGST-----......--QQ.QYNNIRQAVVLT-
ENSGMOP00000019357  ..MLEQRGARLAQVCKDDVGgqrtlqrk.....WTSFAKSLLLCQPPK------......--QQ.PFDLLQDMFTLQP
ENSGMOP00000008307  spGDLFYTTRIVRLCKGDKK.............FHSYVSLPLGCVRR-------......--GE.EYRLLQ-------
ENSGMOP00000020848  ..------------------.............---------------------......----.-------------
ENSGMOP00000016524  ..QENKNFTFLARMCENDHS.............YYSYTELQLNCSRANT-----......----.-FNKVQVGDKAG-
ENSGMOP00000009068  ..HN----------------.............---------------------......----.-------------
ENSGMOP00000002576  ..F-----------------.............---------------------......----.-------------
ENSGMOP00000002576  ..------------------.............---------------------......----.-------------
ENSGMOP00000020049  ..------------------.............---------------------......----.-------------
ENSGMOP00000011087  ..------------------.............---------------------......----.-------------
ENSGMOP00000020848  ..AGKATHARIGQLCK----.............---------------------......----.-------------
ENSGMOP00000000020  ..------------------.............---------------------......----.-------------
ENSGMOP00000009026  ..GSQAYHTRIVRMCSSDLQ.............IRRYVEMPLQCICTDKRRRRG......VGAVrVFNVLQAAHLAK-
ENSGMOP00000001784  ..------------------.............---------------------......----.-------------
ENSGMOP00000000020  ..------------------.............---------------------......----.-------------
ENSGMOP00000020049  ..------------------.............---------------------......----.-------------
ENSGMOP00000008307  ..------------------.............---------------------......----.-------------
ENSGMOP00000001784  ..------------------.............---------------------......----.-------------
ENSGMOP00000009026  ..------------------.............---------------------......----.-------------
ENSGMOP00000020848  ..------------------.............---------------------......----.-------------
ENSGMOP00000002600  ..------------------.............---------------------......----.-------------


                       290       300       310          320       330           340                3
                         |         |         |            |         |             |                 
d1shyb1               GAQLARQIGASLNDDILFGVFAQSKP..DSA.EPMDRSAMCAFPIKYVNDFFN....KIVNKNNVRCLQH........
ENSGMOP00000018542  --------TRDRKNPLVYTVFSTS--..--S.SVFKGSAVCIYTMNDIRRAFL....GPFAHKEGPNYQWvpfqgk..
ENSGMOP00000020178  --------SKDPKNPVIYAVFTTS--..--S.NIFKGSAVCMYNMADIRRVFL....GPYAHRDGPTYQWvpfqgr..
ENSGMOP00000017684  --------TQDTRNPVIYAVFSVS--..--G.SVFKGSAVCVYSMADIRMVFN....GPFAHKEGPNYQWvaytgk..
ENSGMOP00000020856  --------TRDDKNPVVYGVFTTS--..--S.SIFRGSAVCVYSMADIRAVFN....GPYAHKEGPDHRWveyegr..
ENSGMOP00000021165  --------TQDEKNPVVYALFTTA--..--G.SVFKGSAVCVYSMADIRNVFN....GPFAHKHGHNYQWteytgk..
ENSGMOP00000018073  --------TKDERNPDVYAIFSTI--..--S.NVFQGYAVCVYSMADIREAFN....GPFAHKEGPDFQWkvyegr..
ENSGMOP00000014035  HPE-------DWRNTVFYGVFTSQWY..K--.GASGSSAVCSFTMDQVEKAFS....GRYREVNRDTQQWytynhp..
ENSGMOP00000018909  M-------GDGWENTVFYGVFTSQWY..K--.GASGSSAVCAFTMAQVERAFS....GRYREVNRESQQWytynhp..
ENSGMOP00000008620  --------GQDWGSTIFFGIFHAQ--..--W.GDVDVSAVCQYHISDVKKVFN....GDYNEYQDDSQRWtrytgp..
ENSGMOP00000020841  --------NKDQKNPEIFGLFSTT--..--S.AVFKGYAVCVYQMDDVRASFN....GPFAQRERPGHHWtpyedr..
ENSGMOP00000002572  --------GKDKKNPLIYGLFTTS--..--S.DILNGSAVCVYRMEDMARVFK....GNFLHKEGPQYKWaeftgk..
ENSGMOP00000016637  --------TKDPQNPTLYGVFTTS--..--S.AVFRGSAVCVYSMASIRAAFN....GPFAHKDGPDYRWtefrgr..
ENSGMOP00000010573  --------EADAHSSVFYGVFGLE--..--W.KNIKASAICQYSFADVQSAFD....GPYMEVLDSKWREytgk....
ENSGMOP00000013126  P-------QVSWKECLFYAVFTQQ--..--P.HSPALTAVCSYRVADISAVFSkgkyKNPLPVETSYVKWvmysgd..
ENSGMOP00000014734  ---------GPPRDTVFYGIFGLDXX..X--.RNVKASAVCRFSLSDVQQAFQ....GPYMESQNSGSKWteytgk..
ENSGMOP00000012511  --------AEQPQGLLVFGVFTST--..--S.SVFKGSAVCVYNMADILTVFN....GPFAHREGPNFQWvpfqgr..
ENSGMOP00000007826  --------HING-RDVVMATFSTP--..--Y.NSIPGSAVCAYDMAEIANTFT....GRFKEQKSPDSTWtpvpeer.
ENSGMOP00000002600  --------TQDTKNPVIYGVFSVS--..--G.SVFKGSAVCVYSMADIRMVFN....GPFAHKEGPNYQWvayngk..
ENSGMOP00000013146  ---------HLQGRAVVLGLFSTP--..--P.NSIPGSAVCVFDMQQLAHVFE....GRFKEQKSPESIWtpvpdelv
ENSGMOP00000008088  GRVLAASLNISAQDDVLFTVFAKGQK..QFH.RPPDDSALCVFSIRDINARIK....ERLQSCYQGEGHLeln.....
ENSGMOP00000016786  GATLARSLDVGADDDVLFAVFSKGQK..RRPrLASQDSALCVFSLRKINEKIK....ERLQSCYKGEGTLdla.....
ENSGMOP00000010519  --------QINHRPAVL-GVFTTQ--..--A.NSITGSAVCAFYMDDIEKAFN....GKFKEQRNSESAWspvpeeqv
ENSGMOP00000018508  GRLLANSLGISEDEDILFTVFSQGQK..NRA.KPPKESALCLFTLRRIKEKIK....ERIQSCYKGEGRLslp.....
ENSGMOP00000002677  GRELAAQLGAEEEDDILYGVFAVTGD..D-G.ATEDDSALCAFPVDNVNTAID....DGVDDCCKSGPEQ........
ENSGMOP00000007283  --------DHNWRRSVFYAVFTPQ--..--S.GSSRLSAVCAFSVTAVREVFNe...GKFKTPVAVETSHvkwvmhsg
ENSGMOP00000020916  XXX--XX---------------XXXX..XXX.NSIAASAVCAFNLSAVTQVFS....GPFKFQENSRSAWlp......
ENSGMOP00000003738  --------AEDWRNTLIYAVFTSQ--..--W.GNVGLSAVCVYNMALVDEVFSkg..KYMQKATVEQSHTkwvryngi
ENSGMOP00000001718  --------TQDARNPVVYGVFATA--..--G.SVFKGSAVCVYAMSDIRNVFN....GPFSHKHGHNYQWtpytgk..
ENSGMOP00000019921  PE------GAPADDTLFYGIFTSQWSvfVRS.VNSGQSAVCAFRLGDIKATFS....RNYKVLNRDTLRW........
ENSGMOP00000010771  GRRLAQALGMSEDDDVLFVVFSQGQK..NRS.SPPRETLLCLFTLHHINLAMR....ERIRSCYRGDGRLslp.....
ENSGMOP00000017608  GRELASQLGLKGEEKLLYGAFAEVDE..R-G.VPQRNSAFCIFALAKVNQAID....RGVAACCSKGTEQ........
ENSGMOP00000008910  ---------DNWRDSRVYALFT----..---.SSWNSTAVCVYSMADIDDVFE....KSNFKGYEGD---........
ENSGMOP00000019621  HTD-----RGQGAEAYLFGVFS----..---.RSDRKSALCAFRFGDIEEAIR....QGRRNCSNSPSSDvqvlds..
ENSGMOP00000016677  DPN-------DPATTQFYGLFTSQWR..E--.---ELAAVCVFSLSDINKVMD....GPFKELKKTCENWinpep...
ENSGMOP00000009540  GKELAQSLTESVAS-----------S..PEE.DGDSNSALCMYPLKAINERLE....DIINACYFDMGHRgkpavdi.
ENSGMOP00000009360  --------AQDKRAGVLYGLFS----..---.NPWGRTVICAYSIEDIDQAFS....TSKLRGYSSP---........
ENSGMOP00000019357  PG------GDSSRETLFYGVFTSQCV..PRS.RGSEASAVCGFKIEDIRKVFS....GDYRTFNPDK---........
ENSGMOP00000008307  --------------------------..---.---------------------....-------------........
ENSGMOP00000020848  ----------DPKNPIVYTVFTTS--..--S.NIFKGSAVCLYSMVDIRRVFL....GPYAHRDGPNYQWvpfqgr..
ENSGMOP00000016524  ------------------G-------..VRL.RSRGDSG--MYPLPTINKWLR....DIIQACYSESGLInnkqa...
ENSGMOP00000009068  --------------------------..---.---------------------....-------------........
ENSGMOP00000002576  --------------------------..---.---------------------....-------------........
ENSGMOP00000002576  --------------------------..---.--IPGSAVCAFDMEHLAGVFE....GRFKEQKSPESIWtpvpdel.
ENSGMOP00000020049  --------------------------..---.---------------------....-------------........
ENSGMOP00000011087  --------------------------..---.NSIAASAVCAFNLSAITRAFN....GPFRSQENPRSTWlp......
ENSGMOP00000020848  --------------------------..---.---------------------....-------------........
ENSGMOP00000000020  -----------PDGDTLLGVFAAHLSs.ANT.ETSEASALCRFSLDQLDRSID....STRDLCYTQXXXXxxxxxxxx
ENSGMOP00000009026  --------------------------..---.---------------------....-------------........
ENSGMOP00000001784  --------------------------..NRA.RPPRETALCLFTLRRVKERIK....ERIQSCYRGEGKLslp.....
ENSGMOP00000000020  --------------------------..---.---------------------....-------------........
ENSGMOP00000020049  --------------------------..---.---------------------....-------------........
ENSGMOP00000008307  --------------------------..---.---------------------....-------------........
ENSGMOP00000001784  --------------------------..---.---------------------....-------------........
ENSGMOP00000009026  --------------------------..---.---------------------....-------------........
ENSGMOP00000020848  --------------------------..---.---------------------....-------------........
ENSGMOP00000002600  --------------------------..---.---------------------....-------------........


                      50       360                370       380                                390  
                       |         |                  |         |                                  |  
d1shyb1               .FYGPNHEHCFNRTL.........LRNSSGCEARRDEYRTEFTTALQRV.........................DLFM
ENSGMOP00000018542  .VPYPRPGMCPSKTFgsfds....TKGFPDDVIQFARHHPLMFNPVYPLnrr......................PVFL
ENSGMOP00000020178  .VPYPRPGTCPSKTFggfds....TKDLPDDVITFARGHPAMYNPVHPMggr......................PIVV
ENSGMOP00000017684  .IPYPRPGTCPGGTFtpnmks...TKDYPDEVINFMRNHPTMYNAVYPVhkr......................PLVV
ENSGMOP00000020856  .IPYPRPGTCPSKTYdakikt...TKDFPDEVVSFVRFHPLMHGSVLPLngr......................PVFQ
ENSGMOP00000021165  .IPYPRPGTCPGGTFtpgids...SKDFSDEAVNFMRAHPLMFNAVYPIhrr......................PLVV
ENSGMOP00000018073  .VPYPRPGVCPSKITnqpgrefssTKDLPDAVLQFTRGHPLMWRPVFPAqrr......................PVLV
ENSGMOP00000014035  .VPEPRPGACITNGAreqdips..SLHMPDKVLNFVKDHFLMDSVIRSQ.........................PLLL
ENSGMOP00000018909  .LPEPRPGACVTSRArqagiqs..SLHMPDKVLNFVKDHFLMDSVIRSP.........................PLLL
ENSGMOP00000008620  .VPSPRPGACITNWHrengynh..SLQLPDATLNFAKKHPLMAEEAQAR.........................PLLL
ENSGMOP00000020841  .VPYPRPGSCASKMNgggfss...SKEFPDEVLRFVRAHPVMYRAVQPLhrrp.....................VLLQ
ENSGMOP00000002572  .VPFPRPGTCPSSTYgsyts....TREYPDDVIFFSRTHPLLEEIVAPLger......................PLLV
ENSGMOP00000016637  .I-PTPTGTCPSETYdalyrs...TRDLPDEVVSFVRQHQLMWEPVLPLgnr......................PVLT
ENSGMOP00000010573  .VPEPRPGSCITDVHrsqgins..SRDLPDSVLTFARRHPLVAGQVHPVgar......................PLMF
ENSGMOP00000013126  .VPSPRPGACIDNEArkqginq..TLDLPDRTLQFVKDRPLMDQAVPPIgvg......................PLLV
ENSGMOP00000014734  .VPQPRPGTCMTDELrardial..STSLPDDVLDFVRRHPLMARQVQPLdrh......................PLVY
ENSGMOP00000012511  .IPYPRPGTCPGGAFtpdiqs...TKEFPDDVVTFVRNHPVMFNPVYPVgrr......................PLVV
ENSGMOP00000007826  .VPKPRPGCCAGTMSaekykl...SNEFPDDTLNFVKMHPLMDEAVPSItnr......................PWFL
ENSGMOP00000002600  .IPYPRPGTCPGGTFtpnmks...TKDYPDEVINFMRNHPTMYNAVYPLhkr......................PLVV
ENSGMOP00000013146  pRPRRPGGCAVEGSRfss......SNSLPDEVLNFVKTHPLMDETVPLLghr......................PWVV
ENSGMOP00000008088  .WLLGKDVQCTKAPV.........PIDDSFCGLD-INQPLGGSQLVTGH.........................TLYT
ENSGMOP00000016786  .WLKVKDIPCSSALL.........TIDDDFCGLD-MNAPLGVSEMVRGK.........................PLFS
ENSGMOP00000010519  pKPSRRPGCCAADGSastyks...STTFPDETLTFIKSYPLMDEAVPSVndq......................PYFT
ENSGMOP00000018508  .WLLNKELACINSPL.........QINDDFCGQD-FNQPLGGTSTIEGL.........................PLFI
ENSGMOP00000002677  .LSRGLCHFQPCESC.........PHESMEHNATCRDQPTMVSKPYYRV.........................DLFN
ENSGMOP00000007283  eLPVPRPGACINNAArrlgmgn..SLDLPDKTLQFIRDRPLMDEAVRPLtgrxxxxxxxxxxxxxxxxxxxxxxX---
ENSGMOP00000020916  .FPNPNPDFQCGTIDygs......YVNLTERNLQDAQKFLLMHEVVQPVvpv......................PYFM
ENSGMOP00000003738  .TPSPRPGACIDNAMrqenins..SLHLPDKTLQFVKDHPLLEDPVLPVggr......................PHLI
ENSGMOP00000001718  .IPYPRPGTCPGGTFtpglrs...TKEFSDEAVNFVRAHPLMYQPVYPLhkr......................PLVL
ENSGMOP00000019921  .STRVQEKVANPGECg........LHNASDNTLRFVKDNFLADDSVQPVg........................RSLT
ENSGMOP00000010771  .WLLNKELPCIHTPQ.........QIGDDFCGLV-LNQPLGGLRAIEGT.........................PLYE
ENSGMOP00000017608  .LSRGLCHFQPCENC.........PHEXXXXDDSCRNKPTLVSAPYYRL.........................DLFN
ENSGMOP00000008910  .IPDPRPGTCVKNSR.........GLPY--ATLNVVKDHSEMSEWLHSSih.......................PLAP
ENSGMOP00000019621  .VIQGSGAACIQKGNlvpl.....QPEQLDCGAAHLQHPLALRRPLRAT.........................PLF-
ENSGMOP00000016677  .VPRPRPGQCLNSALraegle...SSLLPDKVLTFTRDHPLMENSVTAA.........................PLLL
ENSGMOP00000009540  .PYFSKRDEFCKTPI.........ADTLVTCGADFLPSPLASKPEFGLT.........................AVE-
ENSGMOP00000009360  .FTGNRPGTXXXXXXxx.......XXXXXXXXXGIIRYHPEIEDVIRPVgva......................PLDL
ENSGMOP00000019357  .--------------.........-------------------------.........................----
ENSGMOP00000008307  .--------------.........-------------------------.........................----
ENSGMOP00000020848  .VPYPRPGTCPSKTFggfdt....TKDLPDDVVTFARSHPAMFHPVYPInnk......................PIMV
ENSGMOP00000016524  .VYYPY-TSKTEEKD.........RADRFKCGEEFLPSPLASTPEFALTte.......................PT--
ENSGMOP00000009068  .--------------.........-------------------------.........................----
ENSGMOP00000002576  .--------------.........-------------------------.........................----
ENSGMOP00000002576  .IPKPRPGGCAVQGTrfns.....SNAFPDEMLTFVKTHPLMEEAVASLgqr......................PWIV
ENSGMOP00000020049  .--------------.........-------------------------.........................----
ENSGMOP00000011087  .TPNPIHNFQCGTIEdgggp....NEGLTERSLQEAQRLYLMNDVVQPVsvd......................PLVM
ENSGMOP00000020848  .--------------.........-------------------------.........................----
ENSGMOP00000000020  xXXXXXXXXXXXXXN.........TLEAYPCGSDHTPSPMASRIPLEAE.........................AVLV
ENSGMOP00000009026  .--------------.........-------------------------.........................----
ENSGMOP00000001784  .WLLNKELACINSPL.........QIDDNFCGQD-FNQPLGGTSTIEGI.........................PLFV
ENSGMOP00000000020  .--------------.........-------------------------.........................----
ENSGMOP00000020049  .--------------.........TLEAYPCGSDHTPSPMASRTPVVAE.........................TILH
ENSGMOP00000008307  .--------------.........PIDDHFCGLD-INQPLGGSQLVSSQ.........................ALYT
ENSGMOP00000001784  .--------------.........-------------------------.........................----
ENSGMOP00000009026  .--------------.........-------------YRLEVVQDAQRL.........................EYWQ
ENSGMOP00000020848  .--------------.........-------------------------.........................----
ENSGMOP00000002600  .--------------.........-------------------------.........................----


                           400            410           420       430                  440          
                             |              |             |         |                    |          
d1shyb1               GQFSEVLLTSISTFIK.....GDLTIANLGT....SEGRFMQVVVSRS....G.......PSTPHVNFLLD.......
ENSGMOP00000018542  RTNVEYSFTQVAVDRVnaad.GQYDVMFIGT....DKGTVLKVISVPK....ErwnnmedLLLEELEVFKD.......
ENSGMOP00000020178  RTDVDYQFSQLVVDRVeaed.GQYDVMFIGT....DMGTVLKVVTIPR....EswhdleeVVLEEMTVFRE.......
ENSGMOP00000017684  RTNVDYEFTTITVDQVaaad.GSYEVLFLGT....DRGTVQKVIVLPR....D.......DLLTEELVLEEvevfrv.
ENSGMOP00000020856  LVRAEYTLTQIVVDRVsaed.GQYEVMFLGT....DAGSVLKVVSIAQ....Enwsree.VVLEELQVFQV.......
ENSGMOP00000021165  RSGVDYRYTAMVVDQVdavd.GRYEVLFLGTvtltDHGTVQKVIVLPK....D.......PTNLEELTLEEvevfr..
ENSGMOP00000018073  RANTPYKLTQIVVDRVeaed.SQYDVMFIGT....DVGTVLKVISLRN....GnsleseeVTLEELQVFKV.......
ENSGMOP00000014035  K--RNVRYTQIAVHQFqavp.KAYDVLFIGT....DDGRLHKAININN....Km......YIIEEMVIFPD.......
ENSGMOP00000018909  K--RNVRYTQIAVHKIqgme.RAYDVLFIGT....DDGKLHKAINTND....Rm......HIIEEMTLFAT.......
ENSGMOP00000008620  T--KGVNFTRLAVDRVstldqRSCNMLFIGT....ADGWLQRVVVLGL....Ea......HVIEEIQLFET.......
ENSGMOP00000020841  TQGGGRRLTQLAVDRVqaqd.GHYHVLYIGT....DDSVVLKVITIYNkdtdTvee....VLLEELQVFQV.......
ENSGMOP00000002572  RVGVHYKFTKLVVDRVeavd.GTXXXXXXXX....XSGLVLKSIHLPR....Ddgqsqe.ITLEELQVFKL.......
ENSGMOP00000016637  LSSAPYCLRKVVVDRVetde.GPFDVLHLGT....DDGRLLKAVSVMK....D.......SRHVE------.......
ENSGMOP00000010573  --KRNVNYVKIAVHKVtaldgDVYPVFFLGT....DHGWLHRAVDIAG....Em......HIIEELQLFDK.......
ENSGMOP00000013126  Q--RGAAFSRIVVTRVmafddQKYHVAFIGTv...ESGTLVKAVNYDG....Km......FIIEEVQLFPS.......
ENSGMOP00000014734  G--RTTDYTHMAVDAVlgldgQTYHVLFMGT....DDGRLHRAVSVDD....Hl......HIIEELQLFEA.......
ENSGMOP00000012511  RTGANYKYTSVAVDQVaaad.GNYQVLFLGT....XXXXXXXXXXXXX....Xxxxxxx.XXXXXXXXXXN.......
ENSGMOP00000007826  KTMVRYRLTRIAVDNEagpy.SNQTVVFLGS....ERGIILKFLAKMD....S.......GFLNDSLFLE-.......
ENSGMOP00000002600  RTNVDYEFTTITVDQVtaad.GNYEVLFLGT....DRGTVQKLIVLPS....Ngslded.LVLEELEVFKV.......
ENSGMOP00000013146  RTMGRYQLTTMVVDTEagpq.RNRTVLFLGS....TRGTVLKFLMVPS....Ge......PVAHSSVFLEEvegfnpe
ENSGMOP00000008088  E--SRDRMTSVTAYVY.....NGYCVAFVGT....KSGRLKKIRVDGP....Phgg....VQYETISVIKD.......
ENSGMOP00000016786  D--ATDKMTSVIAYVY.....KNHSLVFVGT....KGGFVKKIRVDGS....Sr......ALQYETVKAVD.......
ENSGMOP00000010519  RTTSRFKLTQITVDTSagpy.KNHTVVFLGS....ENGRLLKILASTQ....Gs......NASFSTALLEDidvynpe
ENSGMOP00000018508  D--KDDGMTSVAAYDY.....RGNTVVFVGT....RNGKMKKILVNSV....Spnspa..LLYEKVTVSET.......
ENSGMOP00000002677  RQMQDVLLTSLLVTII.....ENKTVAHIGT....STGRLLQLVLTRS....S.......PVIFANYSLVE.......
ENSGMOP00000007283  ----------------.....XXXXXXXXXX....XNGFIQKAVNYEG....Em......FVIEETQVYED.......
ENSGMOP00000020916  E--DNVRFTHVAVDVVqgkd.QLFHIIYLATv...DYGTIRKVLSPLN....Qsmgn...CLLEEIELFPPrk.....
ENSGMOP00000003738  T--KDVNYTQIATGRR.....--WTVAP-TT....SSSPAPSVLDEGE....V.......HVVEEIQLIKS.......
ENSGMOP00000001718  STAGDHRFTSIAVDIVdatd.GKYEVLFLGT....DRGTVQKVIVLPK....Dassteq.LILEEVEVFRT.......
ENSGMOP00000019921  MVSHDKKYSHLAAQRVraanhRXXXXXXXXX....XSGYLHKAVLLEQ....Ga......HIVEEVQVFEQ.......
ENSGMOP00000010771  E--REEGLGAVAGYVY.....GEHTVVFVGT....RSGQLKKIRVDGI....Pppsqn..ALLYETVTVGE.......
ENSGMOP00000017608  RQMHDVLFTTVLVTTK.....GNDTLGHFGT....SDGRILQVVLKLD....S.......VFF--ANFSLG.......
ENSGMOP00000008910  FYVSSYNYTKLAVDRVraadqHTYNVLLLAT....DTGKIHKCLELGS....D.......TFIISETHLSN.......
ENSGMOP00000019621  ---EYTGLSSVAVDSV.....HNHTVVFLGT....HHGRLRKLTFLKN....Ft......LANQWTLKLPA.......
ENSGMOP00000016677  R--RGVTYTKLAVTLAda...GPGALLHLGT....DRGEIHRVAVVGQ....Nt......TLLQEVPLFPA.......
ENSGMOP00000009540  ---VRGLLTAVAIAVE.....NDHTIAFLGN....DQGEVSKAHLKGT....S.......EIFGKIPGLTA.......
ENSGMOP00000009360  P--TDDQITHTVADIVlavndEHYSVLYLGT....EQGKVLKVLHTSE....Da......FVIAQYTLFHN.......
ENSGMOP00000019357  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000008307  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000020848  KTDVDYQFTQIVVDKVeaed.GQYDVMFIGT....DIGTVMKVVSVPR....GswhdleeVLLEEMTVFRE.......
ENSGMOP00000016524  -LVRKGHVTAVAVALE.....MEHAVAFLGT....ATGEVLKVHLSAQ....Tp......EVYGRTAGEVT.......
ENSGMOP00000009068  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000002576  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000002576  RTMVRYQLNKMVVDSEagph.RNRTVLFLGS....SRGSILKFLIVPN....Qd......NSVTSSNVFLEelegynp
ENSGMOP00000020049  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000011087  Q--DDVRFSSLVVDIVqgmd.TLYHVMYIGT....EYGTILKALATTN....Kslq....GCYLEEMELLPpgv....
ENSGMOP00000020848  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000000020  S--RSARLTAVAVDVR.....EGHSVAFLGD....SKGNLHKVFLGSD....Gq......VKTYAVASVRP.......
ENSGMOP00000009026  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000001784  D--KEDGMTSVAAYDY.....HGNTVAFAGT....RNGHLKKVGXXXX....Xxxxxx..XXXYEEVVVSE.......
ENSGMOP00000000020  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000020049  S--PSARLTAVAVSVR.....DDHTIAFLGD....SKGNLHKVYLGPN....Ge......VEEYAVVPVQP.......
ENSGMOP00000008307  E--SRDRLTSVTSYVY.....NGHSVVFLGT....RSGMLKKVRVHGS....Pqag....VVYETLSVMKD.......
ENSGMOP00000001784  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000009026  KDLTDTLVTSISVAMV.....HGHIVAYLGT....EDGRHIQVLFSR-....-.......AASPHVNVRLD.......
ENSGMOP00000020848  ----------------.....----------....-------------....-.......-----------.......
ENSGMOP00000002600  ----------------.....----------....-------------....-.......-----------.......


                                  450       460       470                               
                                    |         |         |                               
d1shyb1               ........SHPVSPEVIVEHTLNQNGYTLVITGKKITKIPL.........................
ENSGMOP00000018542  ........ASSIINMQI----SSKRQQLYVGSDTGIAQVPLhrcsvy...................
ENSGMOP00000020178  ........PTPITAMEL----S-------------------tkqxxxxxxxxxxvsqmplhrcevy
ENSGMOP00000017684  ........PTPITSMRI----SSKRQQLYVGS---------vlgvthlalhrcdvy..........
ENSGMOP00000020856  ........PTPILSMEM----SFKQQQLYVGSSEGLAQV--slsrcply.................
ENSGMOP00000021165  ........NKAAVKTMKI---SSKRQQLYVSSDAGLTQVS-lhrcgvy..................
ENSGMOP00000018073  ........PTPVTSMEI----SAKRQALYVGSPLGVAQVK-lhrcety..................
ENSGMOP00000014035  ........GQPVQHIEL----DSEKGLLYVSTLSGLVEVPV.........................
ENSGMOP00000018909  ........PQPVQHIEL----DPQRGLLFVSSYSGLVEVPVa........................
ENSGMOP00000008620  ........PQPVDSLTI----SHSKKYLYIGSRSEVLQLPLa........................
ENSGMOP00000020841  ........PTTITEIII----SSKKQQLYVGSEVGVAQVR-lhqcely..................
ENSGMOP00000002572  ........ESPVTAMTL----SKKKQWLFVGSREGLSQ---lalyqcely................
ENSGMOP00000016637  ........---------------------------------eiileeltlfqx.............
ENSGMOP00000010573  ........PQPIESLVL----SPIMRSVFVGSYSAVVHVP-m........................
ENSGMOP00000013126  ........REPIKVLKL----SEAKGYLYAGSASGAVQMPLa........................
ENSGMOP00000014734  ........PQPISSLVI----SPAQMSVYVGSPSGVVQLPL.........................
ENSGMOP00000012511  ........QVPVTNLRI----SSKKQQLYVSSDHGVSQVS-lhrcqay..................
ENSGMOP00000007826  ........---------------------------------elnvynper................
ENSGMOP00000002600  ........PTPITTMKI----SSKRQQLYVSSVEGVT----hlalhrcdvy...............
ENSGMOP00000013146  kcgedtpqARQLLSLLL----DRSSHTLLLAFPSCLVRVP-tsrchlh..................
ENSGMOP00000008088  ........GSPVLRDMAF---SLDRNYLYVMSERQVTQVPI.........................
ENSGMOP00000016786  ........GGPVLRDMAF---SPDHYYLYAMSGTQLTRVPV.........................
ENSGMOP00000010519  .rcnvhgeDRRVLGLEL----DRDNHAMFVAFSSCVIRVPLsrcsey...................
ENSGMOP00000018508  ........GSPLLRDMLF---SPDQQHIYTLTDKQTSRVPV.........................
ENSGMOP00000002677  ........NQRVSSIAA----VYSSEYLLFVVGDKMFQVP-.........................
ENSGMOP00000007283  ........PQPITTLRL----SSTKGHVYAGSTSGVVQMPV.........................
ENSGMOP00000020916  ........RQHIRSLLI----LHSRSELYVGVRDQVLKIPLkrcnyh...................
ENSGMOP00000003738  ........GGAIKNLLL----SSETRSLYAGSDSGVVQSP-.........................
ENSGMOP00000001718  ........PTTIKTMRL----SSKRQQLYVTSDRGLTQVS-lhrcgvy..................
ENSGMOP00000019921  ........HQSTVGMQL----SVSQGVVFVGTSEGVVRVPVa........................
ENSGMOP00000010771  ........GRPILRDMVF---SPDHQYIYLLSNHQVTRLPV.........................
ENSGMOP00000017608  ........GTPVSGVSS----VYTEDLLLFVAGNKVFTV--.........................
ENSGMOP00000008910  ........HSSVQSMIL----SSKKKKLIVSFAEEVF----ildl.....................
ENSGMOP00000019621  ........SQPVHPIMTFDPN--DSNFLYLMTTHYLLRVKV.........................
ENSGMOP00000016677  ........DQPINNIVLH------KG---------------qalvgtpqflarv............
ENSGMOP00000009540  ........GERVNKNLFF---DHGEDYLYITTEKKITRVPV.........................
ENSGMOP00000009360  ........EGPVQNMAI----DGPKGHLYVGTAMEVQRLQ-ladcgry..................
ENSGMOP00000019357  ........---------------------------------hhws.....................
ENSGMOP00000008307  ........---------------------------------xx.......................
ENSGMOP00000020848  ........PTAI-----------------------------tamelstkq................
ENSGMOP00000016524  ........GDKVNKNLLF---DRHLQHLYITTETKITKVAV.........................
ENSGMOP00000009068  ........---------------------------------slgkvr...................
ENSGMOP00000002576  ........---------------------------------nylekx...................
ENSGMOP00000002576  ...dnrcgESPQAKQLLSLTLDKPSHTLLLAFPSCVVRVPVarcqly...................
ENSGMOP00000020049  ........---------------------------------rlseydh..................
ENSGMOP00000011087  ........HEPILSLQI----LHSDRSLFVGLSDRVLKIPLercsty...................
ENSGMOP00000020848  ........---------------------------------.........................
ENSGMOP00000000020  ........NAPIHGDLLL---DHSRAQIYIMTSNTVEKRPV.........................
ENSGMOP00000009026  ........---------------------------------v........................
ENSGMOP00000001784  ........GKAILRDLLF---SPDHQHLYALTEKQ------.........................
ENSGMOP00000000020  ........---------------------------------rp.......................
ENSGMOP00000020049  ........NTPISSDLIL---DQKEEHLFIMTSTMLQKRPV.........................
ENSGMOP00000008307  ........SSSILRDMAF---SLDRSYLYVLSETQVVQVPV.........................
ENSGMOP00000001784  ........---------------------------------q........................
ENSGMOP00000009026  ........SRPVTTMVLLDPE-GPGGALLLATGSKITKVPL.........................
ENSGMOP00000020848  ........---------------------------------pstarrdeckwagkdl.........
ENSGMOP00000002600  ........---------------------------------rrtecilsgkdtn............


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Refine alignments

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Model: 0049402 (list models)
Initial SAMT99 seed:
Alignment:



Display Options:
Output in FASTA-like format: NoYes
Output column indices: NoYes
Sequence index (number) on each line: NoYes

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Add alignments from genomes

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Select to display   Genome
NoYes   Danio rerio 58 (pseudogenes) - Zebrafish
NoYes   Gallus gallus 58 (pseudogene) - Chicken
NoYes   Homo sapiens 58 (pseudogenes) - Human
NoYes   Homo sapiens 76_38 - Human
NoYes   Pan troglodytes 76_2.1.4 - Chimpanzee
NoYes   Gorilla gorilla 76_3.1 - Western gorilla
NoYes   Pongo abelii 76_2 - Sumatran orangutan
NoYes   Tarsius syrichta 76_1
NoYes   Nomascus leucogenys 76_1.0 - Northern white-cheeked gibbon
NoYes   Papio anubis 76 - Olive baboon
NoYes   Macaca mulatta 76_1 - Rhesus monkey
NoYes   Callithrix jacchus 76_3.2.1 - White-tufted-ear marmoset
NoYes   Otolemur garnettii 76_3 - Small-eared galago
NoYes   Microcebus murinus 76_1 - Gray mouse lemur
NoYes   Rattus norvegicus 76_5.0 - Norway rat
NoYes   Mus musculus 76_38 - House mouse
NoYes   Dipodomys ordii 76_1 - Ord's kangaroo rat
NoYes   Ictidomys tridecemlineatus 76_2 - Thirteen-lined ground squirrel
NoYes   Heterocephalus glaber v1.7-2 - Naked mole-rat
NoYes   Cavia porcellus 76_3 - Domestic guinea pig
NoYes   Oryctolagus cuniculus 76_2 - Rabbit
NoYes   Ochotona princeps 76 - American pika
NoYes   Tupaia belangeri 76 - Northern tree shrew
NoYes   Sus scrofa 76_10.2 - Pig
NoYes   Bos taurus 76_3.1 - Cattle
NoYes   Ovis aries 76_3.1 - Sheep
NoYes   Vicugna pacos 76_1 - Alpaca
NoYes   Tursiops truncatus 76_1 - Bottlenose dolphin
NoYes   Mustela putorius furo 76_1.0 - Domestic ferret
NoYes   Ailuropoda melanoleuca 76_1 - Giant panda
NoYes   Canis familiaris 76_3.1 - Dog
NoYes   Felis catus 76_6.2 - Domestic cat
NoYes   Equus caballus 76_2 - Horse
NoYes   Myotis lucifugus 76_2.0 - Little brown bat
NoYes   Pteropus vampyrus 76_1 - Large flying fox
NoYes   Sorex araneus 76_1 - European shrew
NoYes   Erinaceus europaeus 76 - Western European hedgehog
NoYes   Procavia capensis 76_1 - Cape rock hyrax
NoYes   Loxodonta africana 76_3 - African savanna elephant
NoYes   Echinops telfairi 76 - Small Madagascar hedgehog
NoYes   Dasypus novemcinctus 76_2 - Nine-banded armadillo
NoYes   Choloepus hoffmanni 76_1 - Hoffmann's two-fingered sloth
NoYes   Macropus eugenii 76_1.0 - Tammar wallaby
NoYes   Sarcophilus harrisii 76_7.0 - Tasmanian devil
NoYes   Monodelphis domestica 76_5 - Gray short-tailed opossum
NoYes   Ornithorhynchus anatinus 76_5 - Platypus
NoYes   Saccoglossus kowalevskii v3.0
NoYes   Petromyzon marinus 76_7.0 - Sea lamprey
NoYes   Meleagris gallopavo 76_2 - Turkey
NoYes   Gallus gallus 76_4 - Chicken
NoYes   Anas platyrhynchos 76_1.0 - Mallard
NoYes   Taeniopygia guttata 76_3.2.4 - Zebra finch
NoYes   Ficedula albicollis 76_1.0 - Collared flycatcher
NoYes   Pelodiscus sinensis 76_1.0 - Chinese soft-shelled turtle
NoYes   Anolis carolinensis 76_2.0 - Green anole
NoYes   Xenopus laevis - African clawed frog
NoYes   Xenopus tropicalis 76_4.2 - Tropical clawed frog
NoYes   Latimeria chalumnae 76_1 - Coelacanth
NoYes   Lepisosteus oculatus 76 - Spotted gar
NoYes   Gadus morhua 76_1 - Atlantic cod
NoYes   Tetraodon nigroviridis 76_8 - Spotted green pufferfish
NoYes   Takifugu rubripes 76_4 - Torafugu
NoYes   Gasterosteus aculeatus 76_1 - Three-spined stickleback
NoYes   Oryzias latipes 76_1 - Japanese medaka
NoYes   Xiphophorus maculatus 76_4.4.2 - Southern platyfish
NoYes   Poecilia formosa 76 - Amazon molly
NoYes   Oreochromis niloticus 76_1.0 - Nile tilapia
NoYes   Astyanax mexicanus 76 - Mexican tetra
NoYes   Danio rerio 76_9 - Zebrafish
NoYes   Oikopleura dioica
NoYes   Ciona savignyi 76_2.0 - Pacific transparent sea squirt
NoYes   Ciona intestinalis 76 - Vase tunicate
NoYes   Strongylocentrotus purpuratus v3.1 - Purple sea urchin
NoYes   Adineta vaga
NoYes   Octopus bimaculoides 280
NoYes   Crassostrea gigas 22 - Pacific oyster
NoYes   Lottia gigantea - Owl limpet
NoYes   Helobdella robusta
NoYes   Capitella sp. I
NoYes   Danaus plexippus OGS1.0 - Monarch butterfly
NoYes   Heliconius melpomene - Postman butterfly
NoYes   Bombyx mori - Domestic silkworm
NoYes   Nasonia vitripennis - Jewel wasp
NoYes   Apis mellifera 38.2d - Honey bee
NoYes   Harpegnathos saltator v3.3 - Jerdon's jumping ant
NoYes   Linepithema humile v1.1 - Argentine ant
NoYes   Pogonomyrmex barbatus v1.2 - Red harvester ant
NoYes   Solenopsis invicta v.2.2.3 - Red fire ant
NoYes   Acromyrmex echinatior v3.8 - Panamanian leafcutter ant
NoYes   Atta cephalotes v1.1
NoYes   Camponotus floridanus v3.3 - Florida carpenter ant
NoYes   Lucilia cuprina - Australian sheep blowfly
NoYes   Drosophila grimshawi 1.3
NoYes   Drosophila willistoni 1.3
NoYes   Drosophila pseudoobscura 2.13
NoYes   Drosophila persimilis 1.3
NoYes   Drosophila suzukii
NoYes   Drosophila yakuba 1.3
NoYes   Drosophila simulans 1.3
NoYes   Drosophila sechellia 1.3
NoYes   Drosophila melanogaster 76_5 - Fruit fly
NoYes   Drosophila erecta 1.3
NoYes   Drosophila ananassae 1.3
NoYes   Drosophila virilis 1.2
NoYes   Drosophila mojavensis 1.3
NoYes   Megaselia scalaris 22
NoYes   Aedes aegypti 55 - Yellow fever mosquito
NoYes   Culex pipiens quinquefasciatus - Southern house mosquito
NoYes   Anopheles darlingi 22 - American malaria mosquito
NoYes   Anopheles gambiae 49_3j - African malaria mosquito
NoYes   Tribolium castaneum 3.0 - Red flour beetle
NoYes   Pediculus humanus corporis - Human body louse
NoYes   Acyrthosiphon pisum - Pea aphid
NoYes   Rhodnius prolixus 22
NoYes   Daphnia pulex - Common water flea
NoYes   Strigamia maritima 22
NoYes   Sarcoptes scabiei
NoYes   Tetranychus urticae - Two-spotted spider mite
NoYes   Ixodes scapularis - Black-legged tick
NoYes   Pristionchus pacificus
NoYes   Meloidogyne incognita - Southern root-knot nematode
NoYes   Meloidogyne hapla
NoYes   Onchocerca volvulus 22
NoYes   Brugia malayi WS250 - Agent of lymphatic filariasis
NoYes   Caenorhabditis japonica
NoYes   Caenorhabditis brenneri
NoYes   Caenorhabditis remanei
NoYes   Caenorhabditis elegans 76_235 - Roundworm
NoYes   Caenorhabditis briggsae 2
NoYes   Trichinella spiralis 22
NoYes   Hymenolepis microstoma
NoYes   Echinococcus multilocularis
NoYes   Echinococcus granulosus
NoYes   Taenia solium - Pork tapeworm
NoYes   Schistosoma mansoni
NoYes   Mnemiopsis leidyi - Sea walnut
NoYes   Acropora digitifera v1.0
NoYes   Nematostella vectensis 1.0 - Starlet sea anemone
NoYes   Hydra vulgaris
NoYes   Amphimedon queenslandica
NoYes   Trichoplax adhaerens
NoYes   Proterospongia sp. ATCC 50818
NoYes   Monosiga brevicollis
NoYes   Xenopus (Silurana) tropicalis v7.1 (annotation v7.2) - Tropical clawed frog
NoYes   Drosophila melanogaster FlyBase 5.12 - Fruit fly
NoYes   Anopheles gambiae VectorBase AgamP3.6 - African malaria mosquito
NoYes   Ascaris suum Victoria/Ghent - Pig roundworm
NoYes   Caenorhabditis elegans WormBase WS218 - Roundworm
NoYes   Homo sapiens 69_37 - Human
NoYes   Pan troglodytes 69_2.1.4 - Chimpanzee
NoYes   Gorilla gorilla 69_3.1 - Western gorilla
NoYes   Pongo abelii 69_2 - Sumatran orangutan
NoYes   Nomascus leucogenys 69_1.0 - Northern white-cheeked gibbon
NoYes   Macaca mulatta 69_1 - Rhesus monkey
NoYes   Callithrix jacchus 69_3.2.1 - White-tufted-ear marmoset
NoYes   Otolemur garnettii 69_3 - Small-eared galago
NoYes   Tarsius syrichta 69_1
NoYes   Microcebus murinus 69_1 - Gray mouse lemur
NoYes   Rattus norvegicus 69_3.4 - Norway rat
NoYes   Mus musculus 69_38 - House mouse
NoYes   Dipodomys ordii 69_1 - Ord's kangaroo rat
NoYes   Ictidomys tridecemlineatus 69_2 - Thirteen-lined ground squirrel
NoYes   Cavia porcellus 69_3 - Domestic guinea pig
NoYes   Oryctolagus cuniculus 69_2 - Rabbit
NoYes   Ochotona princeps 69 - American pika
NoYes   Tupaia belangeri 69 - Northern tree shrew
NoYes   Sus scrofa 69_10.2 - Pig
NoYes   Bos taurus 69_3.1 - Cattle
NoYes   Vicugna pacos 69_1 - Alpaca
NoYes   Tursiops truncatus 69_1 - Bottlenose dolphin
NoYes   Mustela putorius furo 69_1.0 - Domestic ferret
NoYes   Ailuropoda melanoleuca 69_1 - Giant panda
NoYes   Canis familiaris 69_3.1 - Dog
NoYes   Felis catus 69 - Domestic cat
NoYes   Equus caballus 69_2 - Horse
NoYes   Myotis lucifugus 69_2.0 - Little brown bat
NoYes   Pteropus vampyrus 69_1 - Large flying fox
NoYes   Sorex araneus 69_1 - European shrew
NoYes   Erinaceus europaeus 69 - Western European hedgehog
NoYes   Procavia capensis 69_1 - Cape rock hyrax
NoYes   Loxodonta africana 69_3 - African savanna elephant
NoYes   Echinops telfairi 69 - Small Madagascar hedgehog
NoYes   Dasypus novemcinctus 69_2 - Nine-banded armadillo
NoYes   Choloepus hoffmanni 69_1 - Hoffmann's two-fingered sloth
NoYes   Macropus eugenii 69_1.0 - Tammar wallaby
NoYes   Sarcophilus harrisii 69_7.0 - Tasmanian devil
NoYes   Monodelphis domestica 69_5 - Gray short-tailed opossum
NoYes   Ornithorhynchus anatinus 69_5 - Platypus
NoYes   Petromyzon marinus 69_7.0 - Sea lamprey
NoYes   Meleagris gallopavo 69_2 - Turkey
NoYes   Gallus gallus 69_2 - Chicken
NoYes   Taeniopygia guttata 69_3.2.4 - Zebra finch
NoYes   Pelodiscus sinensis 69_1.0 - Chinese soft-shelled turtle
NoYes   Anolis carolinensis 69_2.0 - Green anole
NoYes   Xenopus tropicalis 69_4.2 - Tropical clawed frog
NoYes   Latimeria chalumnae 69_1 - Coelacanth
NoYes   Gadus morhua 69_1 - Atlantic cod
NoYes   Tetraodon nigroviridis 69_8 - Spotted green pufferfish
NoYes   Takifugu rubripes 69_4 - Torafugu
NoYes   Gasterosteus aculeatus 69_1 - Three-spined stickleback
NoYes   Oryzias latipes 69_1 - Japanese medaka
NoYes   Xiphophorus maculatus 69_4.4.2 - Southern platyfish
NoYes   Oreochromis niloticus 69_1.0 - Nile tilapia
NoYes   Danio rerio 69_9 - Zebrafish
NoYes   Ciona savignyi 69_2.0 - Pacific transparent sea squirt
NoYes   Ciona intestinalis 69 - Vase tunicate
NoYes   Drosophila melanogaster 69_5 - Fruit fly
NoYes   Caenorhabditis elegans 69_215 - Roundworm
NoYes   Homo sapiens 75_37 - Human
NoYes   Homo sapiens - Human
NoYes   Mus musculus 63_37 (longest transcript per gene) - House mouse
NoYes   Heliconius numata
NoYes   Loa loa v3.3 - Eye worm
NoYes   Wuchereria bancrofti v1.0 - Agent of lymphatic filariasis
NoYes   Brugia malayi v1.0 - Agent of lymphatic filariasis
NoYes   Nicotiana benthamiana 0.4.4
NoYes   NCBI 2017_08 genome
NoYes   STRING v9.0.5 (STRING)
NoYes   Uniprot 2018_03 genome
NoYes   NCBI viral sequences (Viral)
NoYes   PDB chains (SCOP 1.75) (PDB)
NoYes   Protein Data Bank (all PDB sequenc)
NoYes   SCOP2 SCOPe CATH ECOD (all domain sequ)
NoYes   TargetDB (Targets)
NoYes   UniProt viral sequences (Viral)
NoYes   ALL (only advised for small superfamilies)


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