All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
Homeodomain-like | Tetracyclin repressor-like, C-terminal domain | 95 | 3 | |
GroES-like | NAD(P)-binding Rossmann-fold domains | 49 | 8 | |
CheY-like | C-terminal effector domain of the bipartite response regulators | 49 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 43 | 21 | |
Sigma2 domain of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 43 | 6 | |
Homodimeric domain of signal transducing histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 39 | 18 | |
TPR-like | P-loop containing nucleoside triphosphate hydrolases | 34 | 16 | |
lambda repressor-like DNA-binding domains | Periplasmic binding protein-like I | 33 | 1 | |
ACP-like | ACP-like | 30 | 28 | |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 30 | 25 | |
"Winged helix" DNA-binding domain | Periplasmic binding protein-like II | 30 | 1 | |
C-terminal effector domain of the bipartite response regulators | P-loop containing nucleoside triphosphate hydrolases | 30 | 11 | |
Thiolase-like | FabD/lysophospholipase-like | 29 | 25 | |
Thiolase-like | NAD(P)-binding Rossmann-fold domains | 29 | 25 | |
FabD/lysophospholipase-like | NAD(P)-binding Rossmann-fold domains | 28 | 24 | |
Thiolase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 28 | 24 | |
Thiolase-like | ACP-like | 27 | 23 | |
ACP-like | NAD(P)-binding Rossmann-fold domains | 27 | 23 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | NAD(P)-binding Rossmann-fold domains | 27 | 23 | |
FabD/lysophospholipase-like | ACP-like | 26 | 22 | |
NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 26 | 22 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | ACP-like | 26 | 22 | |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 26 | 3 | |
Thiolase-like | Thiolase-like | 25 | 16 | |
C-terminal effector domain of the bipartite response regulators | TPR-like | 25 | 10 | |
Acetyl-CoA synthetase-like | ACP-like | 25 | 20 | |
CoA-dependent acyltransferases | CoA-dependent acyltransferases | 25 | 20 | |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 24 | 4 | |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 24 | 4 | |
Composite domain of metallo-dependent hydrolases | Metallo-dependent hydrolases | 20 | 8 | |
CoA-dependent acyltransferases | ACP-like | 19 | 17 | |
CoA-dependent acyltransferases | Acetyl-CoA synthetase-like | 18 | 16 | |
Actin-like ATPase domain | Actin-like ATPase domain | 17 | 4 | |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 17 | 4 | |
(Trans)glycosidases | Glycosyl hydrolase domain | 17 | 10 | |
Homeodomain-like | Homeodomain-like | 17 | 8 | |
FabD/lysophospholipase-like | FabD/lysophospholipase-like | 16 | 15 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 16 | 15 | |
"Winged helix" DNA-binding domain | GntR ligand-binding domain-like | 16 | 1 | |
TPR-like | TPR-like | 15 | 7 | |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 14 | 7 | |
HAMP domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 13 | 3 | |
Acetyl-CoA synthetase-like | Acetyl-CoA synthetase-like | 13 | 12 | |
HAMP domain-like | Homodimeric domain of signal transducing histidine kinase | 13 | 3 | |
"Winged helix" DNA-binding domain | GAF domain-like | 12 | 1 | |
Dimeric alpha+beta barrel | "Winged helix" DNA-binding domain | 11 | 2 | |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 11 | 5 | |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 11 | 8 | |
(Trans)glycosidases | Carbohydrate-binding domain | 11 | 6 | |
PYP-like sensor domain (PAS domain) | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 11 | 9 | |
"Winged helix" DNA-binding domain | Actin-like ATPase domain | 10 | 2 | |
Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 10 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 10 | 3 | |
Nucleotide cyclase | EAL domain-like | 10 | 6 | |
Galactose-binding domain-like | (Trans)glycosidases | 9 | 9 | |
PYP-like sensor domain (PAS domain) | Homodimeric domain of signal transducing histidine kinase | 9 | 7 | |
cAMP-binding domain-like | "Winged helix" DNA-binding domain | 9 | 2 | |
GAF domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 9 | 8 | |
FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 9 | 3 | |
FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 9 | 3 | |
ACP-like | alpha/beta-Hydrolases | 8 | 8 | |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 8 | 3 | |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 8 | 2 | |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 8 | 3 | |
(Trans)glycosidases | Beta-D-glucan exohydrolase, C-terminal domain | 8 | 3 | |
Protease propeptides/inhibitors | Subtilisin-like | 8 | 4 | |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 7 | 5 | |
CoA-dependent acyltransferases | alpha/beta-Hydrolases | 7 | 7 | |
PYP-like sensor domain (PAS domain) | PYP-like sensor domain (PAS domain) | 7 | 5 | |
"Winged helix" DNA-binding domain | NagB/RpiA/CoA transferase-like | 7 | 1 | |
PYP-like sensor domain (PAS domain) | Nucleotide cyclase | 7 | 3 | |
Acetyl-CoA synthetase-like | alpha/beta-Hydrolases | 7 | 7 | |
PYP-like sensor domain (PAS domain) | EAL domain-like | 7 | 3 | |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 7 | 7 | |
PreATP-grasp domain | Rudiment single hybrid motif | 7 | 5 | |
E set domains | (Trans)glycosidases | 7 | 6 | |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 7 | 4 | |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 7 | 2 | |
Multidrug efflux transporter AcrB transmembrane domain | Multidrug efflux transporter AcrB transmembrane domain | 7 | 4 | |
Hypothetical protein PA1324 | Hypothetical protein PA1324 | 7 | 7 | |
P-loop containing nucleoside triphosphate hydrolases | MOP-like | 6 | 2 | |
GAF domain-like | CheY-like | 6 | 4 | |
(Trans)glycosidases | Ricin B-like lectins | 6 | 4 | |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 6 | 3 | |
Hypothetical protein PA1324 | Ricin B-like lectins | 6 | 4 | |
"Winged helix" DNA-binding domain | Chorismate lyase-like | 6 | 1 | |
Homodimeric domain of signal transducing histidine kinase | CheY-like | 5 | 5 | |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 5 | 4 | |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 5 | 4 | |
Ricin B-like lectins | Pectin lyase-like | 5 | 2 | |
Thiamin diphosphate-binding fold (THDP-binding) | DHS-like NAD/FAD-binding domain | 5 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | GroES-like | 5 | 5 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | CheY-like | 5 | 5 | |
"Winged helix" DNA-binding domain | S-adenosyl-L-methionine-dependent methyltransferases | 5 | 2 | |
MurD-like peptide ligases, catalytic domain | MurD-like peptide ligases, peptide-binding domain | 5 | 4 | |
HAD-like | Calcium ATPase, transmembrane domain M | 5 | 4 | |
Composite domain of metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 5 | 3 | |
Thiolase-like | GroES-like | 5 | 5 | |
Fibronectin type III | Carbohydrate-binding domain | 5 | 4 | |
Calcium ATPase, transduction domain A | HAD-like | 5 | 4 | |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 5 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 5 | 4 | |
Rudiment single hybrid motif | Single hybrid motif | 5 | 4 | |
ACP-like | GroES-like | 5 | 5 | |
PreATP-grasp domain | Single hybrid motif | 5 | 4 | |
GAF domain-like | GAF domain-like | 5 | 4 | |
FabD/lysophospholipase-like | GroES-like | 5 | 5 | |
Galactose-binding domain-like | beta-Galactosidase/glucuronidase domain | 4 | 4 | |
FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 4 | 2 | |
Glycosyl hydrolase domain | Ricin B-like lectins | 4 | 2 | |
GAF domain-like | Homodimeric domain of signal transducing histidine kinase | 4 | 4 | |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 4 | 2 | |
Cna protein B-type domain | Hypothetical protein PA1324 | 4 | 4 | |
E set domains | Glycosyl hydrolase domain | 4 | 3 | |
Six-hairpin glycosidases | Galactose-binding domain-like | 4 | 4 | |
Nucleic acid-binding proteins | RuvA domain 2-like | 4 | 4 | |
Periplasmic binding protein-like II | vWA-like | 4 | 2 | |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 4 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 4 | 2 | |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 4 | 4 | |
Acetyl-CoA synthetase-like | NAD(P)-binding Rossmann-fold domains | 4 | 4 | |
ClpP/crotonase | ClpP/crotonase | 4 | 2 | |
Translation proteins | EF-G C-terminal domain-like | 4 | 2 | |
L30e-like | alpha/beta knot | 4 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | SCP-like | 4 | 2 | |
TPR-like | Nucleotide cyclase | 4 | 4 | |
Glutamine synthetase, N-terminal domain | Glutamine synthetase/guanido kinase | 4 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 4 | 3 | |
Acetyl-CoA synthetase-like | Thiolase-like | 4 | 4 | |
Formate dehydrogenase/DMSO reductase, domains 1-3 | ADC-like | 4 | 3 | |
(Trans)glycosidases | Fibronectin type III | 4 | 3 | |
GroES-like | GroES-like | 4 | 3 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Adenine nucleotide alpha hydrolases-like | 4 | 1 | |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 4 | 3 | |
DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 4 | 1 | |
Subtilisin-like | Galactose-binding domain-like | 4 | 4 | |
Galactose-binding domain-like | Concanavalin A-like lectins/glucanases | 4 | 4 | |
CBS-domain pair | FAD-binding/transporter-associated domain-like | 4 | 1 | |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 4 | 4 | |
Class I glutamine amidotransferase-like | Homeodomain-like | 4 | 1 | |
beta-Galactosidase/glucuronidase domain | (Trans)glycosidases | 4 | 4 | |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 3 | 2 | |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 3 | 2 | |
2Fe-2S ferredoxin-like | CO dehydrogenase ISP C-domain like | 3 | 2 | |
NAD(P)-binding Rossmann-fold domains | Succinyl-CoA synthetase domains | 3 | 2 | |
Hypothetical protein PA1324 | Carboxypeptidase regulatory domain-like | 3 | 3 | |
Concanavalin A-like lectins/glucanases | Arabinanase/levansucrase/invertase | 3 | 2 | |
alpha/beta-Hydrolases | Carbohydrate-binding domain | 3 | 2 | |
Carbohydrate-binding domain | E set domains | 3 | 3 | |
N-terminal domain of MutM-like DNA repair proteins | S13-like H2TH domain | 3 | 1 | |
Acetyl-CoA synthetase-like | FabD/lysophospholipase-like | 3 | 3 | |
Leukotriene A4 hydrolase N-terminal domain | Metalloproteases ("zincins"), catalytic domain | 3 | 2 | |
Single hybrid motif | CoA-dependent acyltransferases | 3 | 2 | |
PYP-like sensor domain (PAS domain) | CheY-like | 3 | 3 | |
NAD(P)-binding Rossmann-fold domains | CoA-dependent acyltransferases | 3 | 3 | |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 3 | 1 | |
(Trans)glycosidases | Class I glutamine amidotransferase-like | 3 | 1 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 3 | 2 | |
ClpP/crotonase | NAD(P)-binding Rossmann-fold domains | 3 | 1 | |
Lysozyme-like | beta-lactamase/transpeptidase-like | 3 | 3 | |
FMN-dependent nitroreductase-like | FMN-dependent nitroreductase-like | 3 | 1 | |
alpha/beta-Hydrolases | Galactose-binding domain-like | 3 | 2 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 3 | 1 | |
ValRS/IleRS/LeuRS editing domain | Nucleotidylyl transferase | 3 | 3 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | GAF domain-like | 3 | 2 | |
Thioesterase/thiol ester dehydrase-isomerase | Thioesterase/thiol ester dehydrase-isomerase | 3 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 3 | 1 | |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 3 | 1 | |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 3 | 3 | |
ClpP/crotonase | 6-phosphogluconate dehydrogenase C-terminal domain-like | 3 | 1 | |
Rhodanese/Cell cycle control phosphatase | Rhodanese/Cell cycle control phosphatase | 3 | 1 | |
Nucleotide-binding domain | FAD-linked reductases, C-terminal domain | 3 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 3 | 2 | |
Protease propeptides/inhibitors | Galactose-binding domain-like | 3 | 3 | |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 3 | 1 | |
Acetyl-CoA synthetase-like | GroES-like | 3 | 3 | |
Arabinanase/levansucrase/invertase | Ricin B-like lectins | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | WD40 repeat-like | 3 | 3 | |
S13-like H2TH domain | Glucocorticoid receptor-like (DNA-binding domain) | 3 | 1 | |
Metallo-dependent phosphatases | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
(Trans)glycosidases | Concanavalin A-like lectins/glucanases | 3 | 3 | |
NAD(P)-binding Rossmann-fold domains | alpha/beta-Hydrolases | 3 | 3 | |
N-terminal domain of MutM-like DNA repair proteins | Glucocorticoid receptor-like (DNA-binding domain) | 3 | 1 | |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 3 | 2 | |
Acetyl-CoA synthetase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 3 | 3 | |
PurM N-terminal domain-like | PurM C-terminal domain-like | 3 | 2 | |
Protein kinase-like (PK-like) | TPR-like | 3 | 3 | |
Carbohydrate-binding domain | Glycosyl hydrolases family 6, cellulases | 3 | 2 | |
GAF domain-like | PP2C-like | 3 | 3 | |
lambda repressor-like DNA-binding domains | RmlC-like cupins | 3 | 1 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 3 | 2 | |
Carboxypeptidase regulatory domain-like | Cna protein B-type domain | 3 | 3 | |
Trypsin-like serine proteases | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 3 | 2 | |
SGNH hydrolase | Carbohydrate-binding domain | 3 | 2 | |
Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 3 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | "Winged helix" DNA-binding domain | 3 | 3 | |
GAF domain-like | PYP-like sensor domain (PAS domain) | 3 | 3 | |
Thiolase-like | alpha/beta-Hydrolases | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 3 | 2 | |
ACT-like | ACT-like | 3 | 3 | |
NAD(P)-binding Rossmann-fold domains | Glutathione synthetase ATP-binding domain-like | 3 | 2 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 3 | 1 | |
Arabinanase/levansucrase/invertase | AbfB domain | 2 | 2 | |
Trypsin-like serine proteases | Pentapeptide repeat-like | 2 | 2 | |
DNA clamp | DNA clamp | 2 | 1 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Nucleotidyltransferase | ACT-like | 2 | 2 | |
MurCD N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 2 | 1 | |
ABC transporter transmembrane region | ABC transporter transmembrane region | 2 | 2 | |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 2 | 1 | |
LanC-like | LanC-like | 2 | 2 | |
Protein kinase-like (PK-like) | LanC-like | 2 | 2 | |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 2 | 2 | |
MurCD N-terminal domain | MurD-like peptide ligases, catalytic domain | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 2 | 1 | |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 2 | 1 | |
Pre-protein crosslinking domain of SecA | Helical scaffold and wing domains of SecA | 2 | 2 | |
(Trans)glycosidases | Starch-binding domain-like | 2 | 2 | |
Trypsin-like serine proteases | Metallo-dependent phosphatases | 2 | 2 | |
Adenine nucleotide alpha hydrolases-like | Homodimeric domain of signal transducing histidine kinase | 2 | 2 | |
Sensory domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Histidine-containing phosphotransfer domain, HPT domain | 2 | 2 | |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 2 | 2 | |
Type II DNA topoisomerase | GyrA/ParC C-terminal domain-like | 2 | 2 | |
Nucleic acid-binding proteins | Translation proteins SH3-like domain | 2 | 2 | |
Starch-binding domain-like | Starch-binding domain-like | 2 | 2 | |
"Winged helix" DNA-binding domain | LexA/Signal peptidase | 2 | 1 | |
NAD(P)-binding Rossmann-fold domains | TrkA C-terminal domain-like | 2 | 1 | |
Nucleotide-diphospho-sugar transferases | UDP-Glycosyltransferase/glycogen phosphorylase | 2 | 1 | |
CorA soluble domain-like | Magnesium transport protein CorA, transmembrane region | 2 | 1 | |
Homeodomain-like | TATA-box binding protein-like | 2 | 2 | |
Molybdenum cofactor biosynthesis proteins | MoeA C-terminal domain-like | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Pre-protein crosslinking domain of SecA | 2 | 2 | |
S-adenosyl-L-methionine-dependent methyltransferases | DNA methylase specificity domain | 2 | 1 | |
Peptidase/esterase 'gauge' domain | alpha/beta-Hydrolases | 2 | 1 | |
Molybdenum cofactor-binding domain | CO dehydrogenase molybdoprotein N-domain-like | 2 | 2 | |
ARM repeat | ARM repeat | 2 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Docking domain B of the erythromycin polyketide synthase (DEBS) | ACP-like | 2 | 2 | |
Trypsin-like serine proteases | PDZ domain-like | 2 | 1 | |
Putative DNA-binding domain | Cobalamin (vitamin B12)-binding domain | 2 | 1 | |
IlvD/EDD N-terminal domain-like | LeuD/IlvD-like | 2 | 1 | |
Translation proteins | Ribosomal protein S5 domain 2-like | 2 | 1 | |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 2Fe-2S ferredoxin-like | 2 | 2 | |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 2 | 1 | |
Aldolase | post-HMGL domain-like | 2 | 2 | |
FabD/lysophospholipase-like | alpha/beta-Hydrolases | 2 | 2 | |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 2 | 2 | |
alpha/beta-Hydrolases | alpha/beta-Hydrolases | 2 | 2 | |
Nicotinate/Quinolinate PRTase N-terminal domain-like | Nicotinate/Quinolinate PRTase C-terminal domain-like | 2 | 1 | |
Docking domain B of the erythromycin polyketide synthase (DEBS) | Thiolase-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Hedgehog/intein (Hint) domain | 2 | 2 | |
DNA ligase/mRNA capping enzyme, catalytic domain | RuvA domain 2-like | 2 | 2 | |
MetI-like | MetI-like | 2 | 2 | |
MoeA N-terminal region -like | Molybdenum cofactor biosynthesis proteins | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | HRDC-like | 2 | 2 | |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 2 | 2 | |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 2 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | Glutathione synthetase ATP-binding domain-like | 2 | 1 | |
Nitrite/Sulfite reductase N-terminal domain-like | Nitrite/Sulfite reductase N-terminal domain-like | 2 | 2 | |
Globin-like | Riboflavin synthase domain-like | 2 | 1 | |
lambda repressor-like DNA-binding domains | TPR-like | 2 | 2 | |
Thiolase-like | CoA-dependent acyltransferases | 2 | 2 | |
Homodimeric domain of signal transducing histidine kinase | Histidine-containing phosphotransfer domain, HPT domain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 2 | 2 | |
Thiolase-like | Thioesterase/thiol ester dehydrase-isomerase | 2 | 2 | |
beta-Galactosidase/glucuronidase domain | beta-Galactosidase/glucuronidase domain | 2 | 2 | |
RuvA domain 2-like | BRCT domain | 2 | 2 | |
TATA-box binding protein-like | DNA-glycosylase | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Helical scaffold and wing domains of SecA | 2 | 2 | |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Pyrimidine nucleoside phosphorylase C-terminal domain | 2 | 1 | |
Homeodomain-like | Ribonuclease H-like | 2 | 2 | |
Carbohydrate-binding domain | Six-hairpin glycosidases | 2 | 2 | |
Molybdenum cofactor-binding domain | Molybdenum cofactor-binding domain | 2 | 2 | |
beta-N-acetylhexosaminidase-like domain | (Trans)glycosidases | 2 | 1 | |
Nitrite/Sulfite reductase N-terminal domain-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 2 | 2 | |
Cobalamin (vitamin B12)-dependent enzymes | Cobalamin (vitamin B12)-binding domain | 2 | 2 | |
HAD-like | Acyl-CoA N-acyltransferases (Nat) | 2 | 2 | |
Nucleotide-diphospho-sugar transferases | Trimeric LpxA-like enzymes | 2 | 1 | |
Nucleotidyltransferase | Nucleotidyltransferase substrate binding subunit/domain | 2 | 2 | |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 2 | 1 | |
MurE/MurF N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 2 | 2 | |
alpha/beta-Hydrolases | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Bet v1-like | Bet v1-like | 2 | 1 | |
(Trans)glycosidases | Galactose mutarotase-like | 2 | 2 | |
HMA, heavy metal-associated domain | HAD-like | 2 | 2 | |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
ThrRS/AlaRS common domain | Class II aaRS and biotin synthetases | 2 | 2 | |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 2 | 1 | |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 2 | 2 | |
Docking domain B of the erythromycin polyketide synthase (DEBS) | NAD(P)-binding Rossmann-fold domains | 2 | 2 | |
SGNH hydrolase | Ricin B-like lectins | 2 | 1 | |
Formyltransferase | FMT C-terminal domain-like | 2 | 1 | |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 2 | 2 | |
CheY-like | PP2C-like | 2 | 2 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | SpoIIaa-like | 2 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | NAD(P)-binding Rossmann-fold domains | 2 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transmembrane domain M | 2 | 2 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 2 | 2 | |
GroEL equatorial domain-like | GroEL-intermediate domain like | 2 | 1 | |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Pentapeptide repeat-like | 2 | 2 | |
Docking domain B of the erythromycin polyketide synthase (DEBS) | FabD/lysophospholipase-like | 2 | 2 | |
Anthrax protective antigen | Concanavalin A-like lectins/glucanases | 2 | 2 | |
beta-Galactosidase/glucuronidase domain | Concanavalin A-like lectins/glucanases | 2 | 2 | |
Docking domain B of the erythromycin polyketide synthase (DEBS) | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 2 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | Succinyl-CoA synthetase domains | 2 | 1 | |
lambda repressor-like DNA-binding domains | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Putative DNA-binding domain | Probable bacterial effector-binding domain | 2 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | Thioesterase/thiol ester dehydrase-isomerase | 2 | 2 | |
Class I glutamine amidotransferase-like | LD-carboxypeptidase A C-terminal domain-like | 2 | 1 | |
Phospholipase D/nuclease | Phospholipase D/nuclease | 2 | 2 | |
Succinyl-CoA synthetase domains | Succinyl-CoA synthetase domains | 2 | 1 | |
Phosphohistidine domain | Phosphoenolpyruvate/pyruvate domain | 2 | 2 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | PP2C-like | 2 | 2 | |
Double Clp-N motif | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
CBS-domain pair | Inosine monophosphate dehydrogenase (IMPDH) | 2 | 1 | |
Adenine nucleotide alpha hydrolases-like | Argininosuccinate synthetase, C-terminal domain | 2 | 2 | |
Homeodomain-like | SIS domain | 2 | 1 | |
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | Pyrimidine nucleoside phosphorylase C-terminal domain | 2 | 1 | |
Alpha-L RNA-binding motif | Pseudouridine synthase | 2 | 1 | |
Metallo-dependent phosphatases | Pentapeptide repeat-like | 2 | 2 | |
Penicillin binding protein dimerisation domain | beta-lactamase/transpeptidase-like | 2 | 1 | |
FabD/lysophospholipase-like | Thioesterase/thiol ester dehydrase-isomerase | 2 | 2 | |
Riboflavin synthase domain-like | 2Fe-2S ferredoxin-like | 2 | 2 | |
Folate-binding domain | Aminomethyltransferase beta-barrel domain | 2 | 1 | |
Globin-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 2 | 1 | |
C-terminal effector domain of the bipartite response regulators | Nucleotide cyclase | 2 | 2 | |
Galactose-binding domain-like | Galactose-binding domain-like | 2 | 2 | |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 2 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | alpha/beta-Hydrolases | 2 | 2 | |
tRNA-binding arm | Class II aaRS and biotin synthetases | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Homing endonucleases | 2 | 2 | |
Pectin lyase-like | Pectin lyase-like | 2 | 2 | |
NAD(P)-binding Rossmann-fold domains | ACT-like | 2 | 2 | |
E set domains | E set domains | 2 | 2 | |
Nucleotide cyclase | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Aldolase | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 2 | 2 | |
MoeA N-terminal region -like | MoeA C-terminal domain-like | 2 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transduction domain A | 2 | 2 | |
Adenine nucleotide alpha hydrolases-like | Adenine nucleotide alpha hydrolases-like | 2 | 1 | |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 2 | 2 | |
Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 2 | 2 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 2 | 1 | |
Glycosyl hydrolase domain | Starch-binding domain-like | 2 | 2 | |
MurE/MurF N-terminal domain | MurD-like peptide ligases, catalytic domain | 2 | 2 | |
Hedgehog/intein (Hint) domain | Homing endonucleases | 2 | 2 | |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 2 | 2 | |
GroEL-intermediate domain like | GroEL apical domain-like | 2 | 1 | |
Homeodomain-like | DNA-glycosylase | 2 | 2 | |
GroEL equatorial domain-like | GroEL apical domain-like | 2 | 1 | |
DinB/YfiT-like putative metalloenzymes | SCP-like | 2 | 1 | |
"Winged helix" DNA-binding domain | PLP-dependent transferases | 2 | 1 | |
Adenine nucleotide alpha hydrolases-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
PYP-like sensor domain (PAS domain) | PP2C-like | 2 | 2 | |
Nucleic acid-binding proteins | BRCT domain | 2 | 2 | |
Glycosyl hydrolase domain | Galactose-binding domain-like | 2 | 2 | |
Phage tail proteins | gp5 N-terminal domain-like | 2 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
Tricorn protease N-terminal domain | ClpP/crotonase | 1 | 1 | |
Tex N-terminal region-like | Nucleic acid-binding proteins | 1 | 1 | |
Methionine synthase domain | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
2Fe-2S ferredoxin-like | Molybdenum cofactor-binding domain | 1 | 1 | |
DAK1/DegV-like | DhaL-like | 1 | 1 | |
PIN domain-like | Ribonuclease H-like | 1 | 1 | |
Fumarylacetoacetate hydrolase, FAH, N-terminal domain | FAH | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 1 | 1 | |
Tricorn protease N-terminal domain | PDZ domain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 1 | 1 | |
"Winged helix" DNA-binding domain | C-terminal domain of transcriptional repressors | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
TGS-like | ACT-like | 1 | 1 | |
CheY-like | CheY-like | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
L9 N-domain-like | Ribosomal protein L9 C-domain | 1 | 1 | |
FAD-binding/transporter-associated domain-like | alpha-helical ferredoxin | 1 | 1 | |
DinB/YfiT-like putative metalloenzymes | C-type lectin-like | 1 | 1 | |
(Trans)glycosidases | AbfB domain | 1 | 1 | |
Dimeric alpha+beta barrel | Dimeric alpha+beta barrel | 1 | 1 | |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 | |
Galactose mutarotase-like | Glycosyl hydrolase domain | 1 | 1 | |
Rho N-terminal domain-like | Nucleic acid-binding proteins | 1 | 1 | |
4Fe-4S ferredoxins | ADC-like | 1 | 1 | |
Cysteine proteinases | Lysozyme-like | 1 | 1 | |
UBA-like | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Nucleotide-diphospho-sugar transferases | 1 | 1 | |
Hedgehog/intein (Hint) domain | GyrA/ParC C-terminal domain-like | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | ACP-like | 1 | 1 | |
Anthrax protective antigen | Anthrax protective antigen | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Tricorn protease domain 2 | 1 | 1 | |
PheT/TilS domain | Putative DNA-binding domain | 1 | 1 | |
"Winged helix" DNA-binding domain | C-terminal domain of arginine repressor | 1 | 1 | |
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | Phosphohistidine domain | 1 | 1 | |
Glycosyl hydrolase domain | Putative glucosidase YicI, C-terminal domain | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
ALDH-like | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 | |
GAF domain-like | EAL domain-like | 1 | 1 | |
Voltage-gated potassium channels | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | 1 | 1 | |
Six-hairpin glycosidases | Ricin B-like lectins | 1 | 1 | |
HD-domain/PDEase-like | TGS-like | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Galactose mutarotase-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Cytochrome c oxidase subunit II-like, transmembrane region | Cupredoxins | 1 | 1 | |
Methionine synthase domain | Methionine synthase activation domain-like | 1 | 1 | |
AbfB domain | AbfB domain | 1 | 1 | |
2Fe-2S ferredoxin-like | CO dehydrogenase molybdoprotein N-domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | CBS-domain pair | 1 | 1 | |
UROD/MetE-like | UROD/MetE-like | 1 | 1 | |
LigT-like | PAP/OAS1 substrate-binding domain | 1 | 1 | |
Trypsin-like serine proteases | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Translation proteins | PRC-barrel domain | 1 | 1 | |
Actin-like ATPase domain | Xylose isomerase-like | 1 | 1 | |
CRISPR-associated protein | CRISPR-associated protein | 1 | 1 | |
Galactose-binding domain-like | AbfB domain | 1 | 1 | |
Cna protein B-type domain | Starch-binding domain-like | 1 | 1 | |
PreATP-grasp domain | post-HMGL domain-like | 1 | 1 | |
PGBD-like | Zn-dependent exopeptidases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Smc hinge domain | 1 | 1 | |
ADC-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
GIY-YIG endonuclease | RuvA domain 2-like | 1 | 1 | |
PRC-barrel domain | MgtE N-terminal domain-like | 1 | 1 | |
Metallo-dependent phosphatases | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 | |
Arabinanase/levansucrase/invertase | Galactose-binding domain-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Galactose-binding domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
RmlC-like cupins | Homeodomain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | YbaK/ProRS associated domain | 1 | 1 | |
E set domains | Fibronectin type III | 1 | 1 | |
Type II DNA topoisomerase | Hedgehog/intein (Hint) domain | 1 | 1 | |
Trypsin-like serine proteases | Ricin B-like lectins | 1 | 1 | |
Class I glutamine amidotransferase-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | ACT-like | 1 | 1 | |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
ACP-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Cryptochrome/photolyase, N-terminal domain | Cryptochrome/photolyase FAD-binding domain | 1 | 1 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleotidylyl transferase | 1 | 1 | |
2Fe-2S ferredoxin-like | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Single hybrid motif | Single hybrid motif | 1 | 1 | |
FMN-binding split barrel | Riboflavin synthase domain-like | 1 | 1 | |
5' to 3' exonuclease, C-terminal subdomain | DNA/RNA polymerases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Carbohydrate-binding domain | Integrin alpha N-terminal domain | 1 | 1 | |
PEP carboxykinase N-terminal domain | PEP carboxykinase-like | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | Inosine monophosphate dehydrogenase (IMPDH) | 1 | 1 | |
PA domain | Zn-dependent exopeptidases | 1 | 1 | |
Carbohydrate-binding domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Homeodomain-like | Hypothetical protein PA1324 | 1 | 1 | |
DNA topoisomerase I domain | DNA breaking-rejoining enzymes | 1 | 1 | |
Ribonuclease PH domain 2-like | Ribonuclease PH domain 2-like | 1 | 1 | |
DNase I-like | PAP/OAS1 substrate-binding domain | 1 | 1 | |
FAD-binding/transporter-associated domain-like | Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain | 1 | 1 | |
Trypsin-like serine proteases | Tricorn protease domain 2 | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | FabD/lysophospholipase-like | 1 | 1 | |
Ricin B-like lectins | PLC-like phosphodiesterases | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Oligoxyloglucan reducing end-specific cellobiohydrolase | 1 | 1 | |
EsxAB dimer-like | Cysteine proteinases | 1 | 1 | |
Translation proteins | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |
Homeodomain-like | Probable bacterial effector-binding domain | 1 | 1 | |
Chondroitin AC/alginate lyase | Galactose mutarotase-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | alpha/beta-Hydrolases | 1 | 1 | |
CoA-transferase family III (CaiB/BaiF) | CoA-transferase family III (CaiB/BaiF) | 1 | 1 | |
GAF domain-like | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Nitrite and sulphite reductase 4Fe-4S domain-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
AraD/HMP-PK domain-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TRCF domain-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Methylglyoxal synthase-like | 1 | 1 | |
N-utilization substance G protein NusG, N-terminal domain | Translation proteins SH3-like domain | 1 | 1 | |
Carbamate kinase-like | ACT-like | 1 | 1 | |
DNA breaking-rejoining enzymes | DNA breaking-rejoining enzymes | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Serine metabolism enzymes domain | 1 | 1 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
lambda repressor-like DNA-binding domains | EPT/RTPC-like | 1 | 1 | |
ACP-like | Rhodanese/Cell cycle control phosphatase | 1 | 1 | |
Translation proteins | ThrRS/AlaRS common domain | 1 | 1 | |
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
"Winged helix" DNA-binding domain | Periplasmic binding protein-like I | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Glutamyl tRNA-reductase dimerization domain | 1 | 1 | |
PIN domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
2Fe-2S ferredoxin-like | 4Fe-4S ferredoxins | 1 | 1 | |
Galactose mutarotase-like | Putative glucosidase YicI, C-terminal domain | 1 | 1 | |
Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 1 | 1 | |
HemD-like | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Thiolase-like | 4'-phosphopantetheinyl transferase | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Nucleotidyltransferase | 1 | 1 | |
PUA domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Translation proteins | 1 | 1 | |
RNase III domain-like | dsRNA-binding domain-like | 1 | 1 | |
alpha/beta-Hydrolases | TPR-like | 1 | 1 | |
Pentapeptide repeat-like | WD40 repeat-like | 1 | 1 | |
FKBP-like | Triger factor/SurA peptide-binding domain-like | 1 | 1 | |
Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 1 | 1 | |
PHP14-like | Phospholipase D/nuclease | 1 | 1 | |
Sensory domain-like | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 | |
Anthrax protective antigen | beta-Galactosidase/glucuronidase domain | 1 | 1 | |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Ricin B-like lectins | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | MesJ substrate recognition domain-like | 1 | 1 | |
ACT-like | HAD-like | 1 | 1 | |
Galactose-binding domain-like | Carbohydrate-binding domain | 1 | 1 | |
FabD/lysophospholipase-like | 4'-phosphopantetheinyl transferase | 1 | 1 | |
(Trans)glycosidases | Chitinase insertion domain | 1 | 1 | |
Nudix | "Winged helix" DNA-binding domain | 1 | 1 | |
AhpD-like | AhpD-like | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | Serine metabolism enzymes domain | 1 | 1 | |
Dimeric alpha+beta barrel | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Periplasmic binding protein-like II | GlnB-like | 1 | 1 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | 1 | 1 | |
Acetyl-CoA synthetase-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Anthrax protective antigen | (Trans)glycosidases | 1 | 1 | |
CO dehydrogenase ISP C-domain like | CO dehydrogenase molybdoprotein N-domain-like | 1 | 1 | |
Ribonuclease H-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
CheW-like | CheW-like | 1 | 1 | |
Heme-dependent peroxidases | Heme-dependent peroxidases | 1 | 1 | |
PIN domain-like | DNA/RNA polymerases | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Aldolase | 1 | 1 | |
GreA transcript cleavage protein, N-terminal domain | FKBP-like | 1 | 1 | |
Lysozyme-like | LysM domain | 1 | 1 | |
HIT-like | HIT-like | 1 | 1 | |
Obg GTP-binding protein N-terminal domain | Obg GTP-binding protein C-terminal domain | 1 | 1 | |
Nucleic acid-binding proteins | PheT/TilS domain | 1 | 1 | |
FMN-binding split barrel | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
PGBD-like | PGBD-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Restriction endonuclease-like | 1 | 1 | |
RmlC-like cupins | Nucleotidylyl transferase | 1 | 1 | |
Dihydropteroate synthetase-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 1 | 1 | |
CbiG N-terminal domain-like | CobE/GbiG C-terminal domain-like | 1 | 1 | |
Glutamyl tRNA-reductase catalytic, N-terminal domain | Glutamyl tRNA-reductase dimerization domain | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Nucleic acid-binding proteins | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
DPP6 N-terminal domain-like | DPP6 N-terminal domain-like | 1 | 1 | |
Tricorn protease N-terminal domain | Metallo-dependent hydrolases | 1 | 1 | |
Ribonuclease PH domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
Obg GTP-binding protein N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Ribonuclease H-like | HRDC-like | 1 | 1 | |
Galactose mutarotase-like | Six-hairpin glycosidases | 1 | 1 | |
Trypsin-like serine proteases | WD40 repeat-like | 1 | 1 | |
DNA/RNA polymerases | Lesion bypass DNA polymerase (Y-family), little finger domain | 1 | 1 | |
Putative DNA-binding domain | ARM repeat | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | ACT-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 1 | 1 | |
Rudiment single hybrid motif | Aldolase | 1 | 1 | |
Nqo1 middle domain-like | Nqo1C-terminal domain-like | 1 | 1 | |
PLP-dependent transferases | PLP-dependent transferases | 1 | 1 | |
Histidine-containing phosphotransfer domain, HPT domain | CheW-like | 1 | 1 | |
Nucleotidylyl transferase | Alpha-L RNA-binding motif | 1 | 1 | |
Aspartate/glutamate racemase | Aspartate/glutamate racemase | 1 | 1 | |
CBS-domain pair | Nucleotide cyclase | 1 | 1 | |
HAD-like | Six-hairpin glycosidases | 1 | 1 | |
PYP-like sensor domain (PAS domain) | Histidine-containing phosphotransfer domain, HPT domain | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 1 | 1 | |
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | Multidrug efflux transporter AcrB transmembrane domain | 1 | 1 | |
PYP-like sensor domain (PAS domain) | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Nucleotidyltransferase | PAP/OAS1 substrate-binding domain | 1 | 1 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | CheY-like | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
MFS general substrate transporter | FMN-binding split barrel | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RecA protein, C-terminal domain | 1 | 1 | |
Subtilisin-like | Cadherin-like | 1 | 1 | |
PYP-like sensor domain (PAS domain) | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 | |
BH3703-like | BH3703-like | 1 | 1 | |
(Trans)glycosidases | (Trans)glycosidases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | PRTase-like | 1 | 1 | |
Fe-S cluster assembly (FSCA) domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
vWA-like | CalX-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TrpR-like | 1 | 1 | |
PTS system fructose IIA component-like | HPr-like | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | Radical SAM enzymes | 1 | 1 | |
MetI-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Ribonuclease H-like | Protein kinase-like (PK-like) | 1 | 1 | |
Radical SAM enzymes | Radical SAM enzymes | 1 | 1 | |
Class I glutamine amidotransferase-like | ADC synthase | 1 | 1 | |
Metallo-dependent phosphatases | 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 1 | 1 | |
CheC-like | Surface presentation of antigens (SPOA) | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase activation domain-like | 1 | 1 | |
RuvA domain 2-like | RuvA domain 2-like | 1 | 1 | |
Type II DNA topoisomerase | Type II DNA topoisomerase | 1 | 1 | |
RuvA domain 2-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Zinc beta-ribbon | DNA primase core | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 1 | 1 | |
2Fe-2S ferredoxin-like | ADC-like | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase activation domain-like | 1 | 1 | |
N-terminal domain of DnaB helicase | Homing endonucleases | 1 | 1 | |
Tricorn protease domain 2 | alpha/beta-Hydrolases | 1 | 1 | |
CheY-like | Methylesterase CheB, C-terminal domain | 1 | 1 | |
Riboflavin kinase-like | FMN-binding split barrel | 1 | 1 | |
Oxidoreductase molybdopterin-binding domain | E set domains | 1 | 1 | |
(Trans)glycosidases | LysM domain | 1 | 1 | |
CarD-like | TRCF domain-like | 1 | 1 | |
"Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 1 | 1 | |
beta-Galactosidase/glucuronidase domain | Galactose mutarotase-like | 1 | 1 | |
Nudix | Phosphoglycerate mutase-like | 1 | 1 | |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Protein kinase-like (PK-like) | Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 1 | 1 | |
Ribonuclease PH domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
Homeodomain-like | Protein kinase-like (PK-like) | 1 | 1 | |
YrdC/RibB | RibA-like | 1 | 1 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 | |
Diaminopimelate epimerase-like | Diaminopimelate epimerase-like | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
E set domains | Carbohydrate binding domain | 1 | 1 | |
ATP-dependent DNA ligase DNA-binding domain | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 | |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 1 | 1 | |
Cupredoxins | Cupredoxins | 1 | 1 | |
N-terminal domain of DnaB helicase | Hedgehog/intein (Hint) domain | 1 | 1 | |
"Winged helix" DNA-binding domain | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
DPP6 N-terminal domain-like | Lysozyme-like | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | 4'-phosphopantetheinyl transferase | 1 | 1 | |
Translation proteins | Translation proteins | 1 | 1 | |
FucI/AraA N-terminal and middle domains | FucI/AraA C-terminal domain-like | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | CoA-dependent acyltransferases | 1 | 1 | |
DNase I-like | Nucleotidyltransferase | 1 | 1 | |
Tricorn protease N-terminal domain | alpha/beta-Hydrolases | 1 | 1 | |
CoA-dependent acyltransferases | Thiamin diphosphate-binding fold (THDP-binding) | 1 | 1 | |
Cytidine deaminase-like | Dihydrofolate reductase-like | 1 | 1 | |
Glutamyl tRNA-reductase catalytic, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Ribonuclease H-like | Phosphoglycerate mutase-like | 1 | 1 | |
Nucleotidyltransferase | TGS-like | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | DHS-like NAD/FAD-binding domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
PurM N-terminal domain-like | PurM N-terminal domain-like | 1 | 1 | |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | NTF2-like | 1 | 1 | |
PDZ domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
(Trans)glycosidases | Putative glucosidase YicI, C-terminal domain | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Putative methyltransferase TM0872, insert domain | 1 | 1 | |
lambda integrase-like, N-terminal domain | DNA breaking-rejoining enzymes | 1 | 1 | |
Homocysteine S-methyltransferase | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
Protein kinase-like (PK-like) | PLP-dependent transferases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | CarD-like | 1 | 1 | |
Dihydropteroate synthetase-like | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
Sm-like ribonucleoproteins | Mechanosensitive channel protein MscS (YggB), C-terminal domain | 1 | 1 | |
PK beta-barrel domain-like | PK C-terminal domain-like | 1 | 1 | |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | CoaB-like | 1 | 1 | |
N-terminal domain of DnaB helicase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
ACT-like | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
Putative DNA-binding domain | Anticodon-binding domain of PheRS | 1 | 1 | |
Pseudouridine synthase | PUA domain-like | 1 | 1 | |
CoA-dependent acyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Galactose-binding domain-like | Ricin B-like lectins | 1 | 1 | |
Thioredoxin-like | NHL repeat | 1 | 1 | |
vWA-like | PKD domain | 1 | 1 | |
Tricorn protease N-terminal domain | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
Metallo-dependent phosphatases | WD40 repeat-like | 1 | 1 | |
PDZ domain-like | ClpP/crotonase | 1 | 1 | |
ATP-dependent DNA ligase DNA-binding domain | Nucleic acid-binding proteins | 1 | 1 | |
Carbohydrate-binding domain | Arabinanase/levansucrase/invertase | 1 | 1 | |
PLP-dependent transferases | Ornithine decarboxylase C-terminal domain | 1 | 1 | |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | CBS-domain pair | 1 | 1 | |
Domain of the SRP/SRP receptor G-proteins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | FMN-linked oxidoreductases | 1 | 1 | |
PRC-barrel domain | CBS-domain pair | 1 | 1 | |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 1 | 1 | |
Thioredoxin-like | GST C-terminal domain-like | 1 | 1 | |
Mechanosensitive channel protein MscS (YggB), transmembrane region | Sm-like ribonucleoproteins | 1 | 1 | |
PPK N-terminal domain-like | PHP14-like | 1 | 1 | |
MalF N-terminal region-like | MetI-like | 1 | 1 | |
Rudiment single hybrid motif | ClpP/crotonase | 1 | 1 | |
Iron-dependent repressor protein, dimerization domain | C-terminal domain of transcriptional repressors | 1 | 1 | |
PreATP-grasp domain | Methylglyoxal synthase-like | 1 | 1 | |
PreATP-grasp domain | PreATP-grasp domain | 1 | 1 | |
Tricorn protease domain 2 | ClpP/crotonase | 1 | 1 | |
MFS general substrate transporter | "Winged helix" DNA-binding domain | 1 | 1 | |
Putative DNA-binding domain | Putative DNA-binding domain | 1 | 1 | |
GAF domain-like | Nucleotide cyclase | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Methylglyoxal synthase-like | 1 | 1 | |
Nucleic acid-binding proteins | Anticodon-binding domain of PheRS | 1 | 1 | |
Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 | |
Galactose-binding domain-like | Anthrax protective antigen | 1 | 1 | |
EAL domain-like | CBS-domain pair | 1 | 1 | |
Glycoside hydrolase/deacetylase | Families 57/38 glycoside transferase middle domain | 1 | 1 | |
MFS general substrate transporter | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FAD-linked oxidases, C-terminal domain | alpha-helical ferredoxin | 1 | 1 | |
Nucleotide-binding domain | FAD/NAD(P)-binding domain | 1 | 1 | |
Nucleotidyltransferase substrate binding subunit/domain | ACT-like | 1 | 1 | |
Trypsin-like serine proteases | Integrin alpha N-terminal domain | 1 | 1 | |
Carbamate kinase-like | PUA domain-like | 1 | 1 | |
Thioesterase/thiol ester dehydrase-isomerase | 4'-phosphopantetheinyl transferase | 1 | 1 | |
4Fe-4S ferredoxins | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Homodimeric domain of signal transducing histidine kinase | CheW-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | post-HMGL domain-like | 1 | 1 | |
PHP domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Nucleotidylyl transferase | An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 1 | 1 | |
Sensory domain-like | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
Rudiment single hybrid motif | post-HMGL domain-like | 1 | 1 | |
ParB/Sulfiredoxin | KorB DNA-binding domain-like | 1 | 1 | |
Ribonuclease H-like | GIY-YIG endonuclease | 1 | 1 | |
NusB-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Glycoside hydrolase/deacetylase | Nucleotide-diphospho-sugar transferases | 1 | 1 | |
DNase I-like | LigT-like | 1 | 1 | |
CbiG N-terminal domain-like | Tetrapyrrole methylase | 1 | 1 | |
GIY-YIG endonuclease | C-terminal UvrC-binding domain of UvrB | 1 | 1 | |
Nucleotidylyl transferase | Riboflavin kinase-like | 1 | 1 | |
Tetrapyrrole methylase | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Homocysteine S-methyltransferase | Dihydropteroate synthetase-like | 1 | 1 | |
Cna protein B-type domain | Ricin B-like lectins | 1 | 1 | |
Nucleic acid-binding proteins | ArfGap/RecO-like zinc finger | 1 | 1 | |
Trigger factor ribosome-binding domain | FKBP-like | 1 | 1 | |
Tricorn protease N-terminal domain | Tricorn protease domain 2 | 1 | 1 | |
Translation initiation factor IF3, N-terminal domain | Translation initiation factor IF3, C-terminal domain | 1 | 1 | |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | TATA-box binding protein-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
ABC transporter involved in vitamin B12 uptake, BtuC | ABC transporter involved in vitamin B12 uptake, BtuC | 1 | 1 | |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 1 | 1 | |
PUA domain-like | alpha/beta knot | 1 | 1 | |
Protein kinase-like (PK-like) | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Nucleic acid-binding proteins | DNA helicase RuvA subunit, C-terminal domain | 1 | 1 | |
WD40 repeat-like | WD40 repeat-like | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | C-terminal domain of RNA polymerase alpha subunit | 1 | 1 | |
FliG | FliG | 1 | 1 | |
Sensory domain-like | Sporulation response regulatory protein Spo0B | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Carbohydrate-binding domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Obg GTP-binding protein C-terminal domain | 1 | 1 | |
Putative DNA-binding domain | Antibiotic binding domain of TipA-like multidrug resistance regulators | 1 | 1 | |
Serine metabolism enzymes domain | ACT-like | 1 | 1 | |
DNA methylase specificity domain | DNA methylase specificity domain | 1 | 1 | |
alpha-helical ferredoxin | Nucleotide-binding domain | 1 | 1 | |
Nqo1 FMN-binding domain-like | Nqo1C-terminal domain-like | 1 | 1 | |
Nucleotide-binding domain | Nucleotide-binding domain | 1 | 1 | |
Ribonuclease H-like | Nucleic acid-binding proteins | 1 | 1 | |
Carbon-nitrogen hydrolase | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
PPK N-terminal domain-like | Phospholipase D/nuclease | 1 | 1 | |
FAD/NAD(P)-binding domain | Thioredoxin-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Tetrapyrrole methylase | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Cobalamin (vitamin B12)-dependent enzymes | 1 | 1 | |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 1 | 1 | |
Nucleotidyltransferase substrate binding subunit/domain | Nucleotidyltransferase substrate binding subunit/domain | 1 | 1 | |
Ribokinase-like | Nucleotidylyl transferase | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 1 | 1 | |
Ricin B-like lectins | Lysozyme-like | 1 | 1 | |
Carboxypeptidase regulatory domain-like | Starch-binding domain-like | 1 | 1 | |
Ribonuclease H-like | RuvA domain 2-like | 1 | 1 | |
ValRS/IleRS/LeuRS editing domain | tRNA-binding arm | 1 | 1 | |
Pectin lyase-like | Carbohydrate-binding domain | 1 | 1 | |
Lysozyme-like | N-acetylmuramoyl-L-alanine amidase-like | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Six-hairpin glycosidases | 1 | 1 | |
GroES-like | CoA-dependent acyltransferases | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Alpha subunit of glutamate synthase, C-terminal domain | 1 | 1 | |
RuvA domain 2-like | DNA helicase RuvA subunit, C-terminal domain | 1 | 1 | |
GroES-like | alpha/beta-Hydrolases | 1 | 1 | |
Protein kinase-like (PK-like) | Carbohydrate-binding domain | 1 | 1 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | PRTase-like | 1 | 1 | |
YbaK/ProRS associated domain | Class II aaRS ABD-related | 1 | 1 | |
Carbohydrate-binding domain | Chitinase insertion domain | 1 | 1 | |
Starch-binding domain-like | E set domains | 1 | 1 | |
Macro domain-like | Zn-dependent exopeptidases | 1 | 1 | |
Kelch motif | Kelch motif | 1 | 1 | |
Nucleic acid-binding proteins | GAD domain-like | 1 | 1 | |
Ribosomal protein L6 | Ribosomal protein L6 | 1 | 1 | |
Acid phosphatase/Vanadium-dependent haloperoxidase | NAD kinase/diacylglycerol kinase-like | 1 | 1 | |
PreATP-grasp domain | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
Thioredoxin-like | Six-hairpin glycosidases | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | Nucleic acid-binding proteins | 1 | 1 | |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
CofE-like | FMN-dependent nitroreductase-like | 1 | 1 | |
HD-domain/PDEase-like | ACT-like | 1 | 1 | |
Rho N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Nucleic acid-binding proteins | 1 | 1 | |
post-HMGL domain-like | Single hybrid motif | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | ACT-like | 1 | 1 | |
Phospholipase D/nuclease | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | Thiamin diphosphate-binding fold (THDP-binding) | 1 | 1 | |
MgtE N-terminal domain-like | CBS-domain pair | 1 | 1 | |
ACP-like | FMN-dependent nitroreductase-like | 1 | 1 | |
WD40 repeat-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
FabD/lysophospholipase-like | CoA-dependent acyltransferases | 1 | 1 | |
PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Cytochrome c | Cytochrome c | 1 | 1 | |
YWTD domain | Calcium-dependent phosphotriesterase | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | Methionine synthase activation domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Hypothetical protein YjiA, C-terminal domain | 1 | 1 | |
Class II aaRS and biotin synthetases | C-terminal domain of transcriptional repressors | 1 | 1 | |
Glutamine synthetase/guanido kinase | GatB/YqeY motif | 1 | 1 | |
Sporulation response regulatory protein Spo0B | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Alpha-L RNA-binding motif | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Class II aaRS and biotin synthetases | HD-domain/PDEase-like | 1 | 1 | |
Acetyl-CoA synthetase-like | FMN-dependent nitroreductase-like | 1 | 1 | |
Sensory domain-like | HAMP domain-like | 1 | 1 | |
Terpenoid cyclases/Protein prenyltransferases | Terpenoid cyclases/Protein prenyltransferases | 1 | 1 | |
Nucleic acid-binding proteins | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
YjeF N-terminal domain-like | Ribokinase-like | 1 | 1 | |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | Homeodomain-like | 1 | 1 | |
YajQ-like | YajQ-like | 1 | 1 | |
Tetrahydrobiopterin biosynthesis enzymes-like | Tetrahydrobiopterin biosynthesis enzymes-like | 1 | 1 | |
Nqo1 FMN-binding domain-like | Nqo1 middle domain-like | 1 | 1 | |
Tricorn protease domain 2 | PDZ domain-like | 1 | 1 | |
FAD/NAD(P)-binding domain | Nitrite and sulphite reductase 4Fe-4S domain-like | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Hypothetical protein PA1324 | Starch-binding domain-like | 1 | 1 | |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |
PheT/TilS domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 | |
CheY-like | HD-domain/PDEase-like | 1 | 1 | |
Sigma2 domain of RNA polymerase sigma factors | Pectin lyase-like | 1 | 1 | |
"Winged helix" DNA-binding domain | Iron-dependent repressor protein, dimerization domain | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | Thiolase-like | 1 | 1 | |
beta-Galactosidase/glucuronidase domain | AbfB domain | 1 | 1 | |
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | TK C-terminal domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal UvrC-binding domain of UvrB | 1 | 1 | |
Poly A polymerase C-terminal region-like | ACT-like | 1 | 1 | |
Trigger factor ribosome-binding domain | Triger factor/SurA peptide-binding domain-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 1 | 1 | |
Carboxypeptidase regulatory domain-like | Carboxypeptidase regulatory domain-like | 1 | 1 | |
YVTN repeat-like/Quinoprotein amine dehydrogenase | Tricorn protease domain 2 | 1 | 1 | |
Nucleotidyltransferase substrate binding subunit/domain | Poly A polymerase C-terminal region-like | 1 | 1 | |
Nucleotidylyl transferase | tRNA-binding arm | 1 | 1 | |
Galactose-binding domain-like | Galactose mutarotase-like | 1 | 1 | |
PH0987 N-terminal domain-like | Cyclophilin-like | 1 | 1 | |
Sigma2 domain of RNA polymerase sigma factors | NTF2-like | 1 | 1 | |
lambda repressor-like DNA-binding domains | C-type lectin-like | 1 | 1 | |
RmlC-like cupins | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | ClpP/crotonase | 1 | 1 | |
Methylglyoxal synthase-like | Cytidine deaminase-like | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Nucleic acid-binding proteins | 1 | 1 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB transmembrane domain | 1 | 1 | |
Cna protein B-type domain | Cna protein B-type domain | 1 | 1 | |
LmbE-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Tex N-terminal region-like | Ribonuclease H-like | 1 | 1 | |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | tRNA-binding arm | 1 | 1 | |
YojJ-like | TPR-like | 1 | 1 | |
NagB/RpiA/CoA transferase-like | alpha-helical ferredoxin | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | vWA-like | 1 | 1 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 | |
Actin-crosslinking proteins | Beta-D-glucan exohydrolase, C-terminal domain | 1 | 1 | |
LysM domain | LysM domain | 1 | 1 | |
HD-domain/PDEase-like | Nucleotidyltransferase | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 1 | 1 | |
MFS general substrate transporter | Riboflavin kinase-like | 1 | 1 | |
PurM C-terminal domain-like | PurM C-terminal domain-like | 1 | 1 | |
(Trans)glycosidases | Actin-crosslinking proteins | 1 | 1 | |
Heme-dependent catalase-like | Class I glutamine amidotransferase-like | 1 | 1 | |
E set domains | Six-hairpin glycosidases | 1 | 1 | |
Sigma2 domain of RNA polymerase sigma factors | (Trans)glycosidases | 1 | 1 | |
PreATP-grasp domain | Aldolase | 1 | 1 | |
CheY-like | Histidine-containing phosphotransfer domain, HPT domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
Terpenoid synthases | Terpenoid synthases | 1 | 1 | |
Class I glutamine amidotransferase-like | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
C-terminal UvrC-binding domain of UvrB | RuvA domain 2-like | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
PreATP-grasp domain | ClpP/crotonase | 1 | 1 | |
ACT-like | Formyltransferase | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase domain | 1 | 1 | |
FAD/NAD(P)-binding domain | Nitrite/Sulfite reductase N-terminal domain-like | 1 | 1 | |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 1 | 1 | |
FMN-linked oxidoreductases | Alpha subunit of glutamate synthase, C-terminal domain | 1 | 1 | |
Galactose-binding domain-like | E set domains | 1 | 1 | |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | DNA-glycosylase | 1 | 1 | |
Tetrapyrrole methylase | Tetrapyrrole methylase | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
post-HMGL domain-like | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 1 | 1 | |
4'-phosphopantetheinyl transferase | 4'-phosphopantetheinyl transferase | 1 | 1 | |
PGBD-like | Lysozyme-like | 1 | 1 | |
Single hybrid motif | ClpP/crotonase | 1 | 1 | |
Class II aaRS and biotin synthetases | GAD domain-like | 1 | 1 | |
Aldolase | Single hybrid motif | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | CheW-like | 1 | 1 | |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase domain | 1 | 1 | |
CobE/GbiG C-terminal domain-like | Tetrapyrrole methylase | 1 | 1 | |
Tetrapyrrole methylase | HemD-like | 1 | 1 | |
Ricin B-like lectins | Ricin B-like lectins | 1 | 1 | |
PP2C-like | SpoIIaa-like | 1 | 1 | |
MFS general substrate transporter | Nudix | 1 | 1 | |
LexA/Signal peptidase | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Ribonuclease PH domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Riboflavin synthase domain-like | Riboflavin synthase domain-like | 1 | 1 | |
Tricorn protease N-terminal domain | Tricorn protease N-terminal domain | 1 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | RBP11-like subunits of RNA polymerase | 1 | 1 | |
GAF domain-like | SpoIIaa-like | 1 | 1 | |
PheT/TilS domain | Anticodon-binding domain of PheRS | 1 | 1 | |
Ribonuclease H-like | DNA/RNA polymerases | 1 | 1 | |
5' to 3' exonuclease, C-terminal subdomain | Ribonuclease H-like | 1 | 1 | |
DPP6 N-terminal domain-like | vWA-like | 1 | 1 | |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 1 | 1 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
Nucleotidyltransferase | Nucleotidyltransferase | 1 | 1 | |
Tex N-terminal region-like | RuvA domain 2-like | 1 | 1 | |
Nucleic acid-binding proteins | Putative DNA-binding domain | 1 | 1 | |
FMN-binding split barrel | 2Fe-2S ferredoxin-like | 1 | 1 | |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 1 | 1 | |
PYP-like sensor domain (PAS domain) | SpoIIaa-like | 1 | 1 | |
Periplasmic binding protein-like II | ACT-like | 1 | 1 | |
RBP11-like subunits of RNA polymerase | C-terminal domain of RNA polymerase alpha subunit | 1 | 1 | |
Cadherin-like | Galactose-binding domain-like | 1 | 1 | |
LigT-like | Nucleotidyltransferase | 1 | 1 | |
CO dehydrogenase ISP C-domain like | Molybdenum cofactor-binding domain | 1 | 1 | |
Mechanosensitive channel protein MscS (YggB), transmembrane region | Mechanosensitive channel protein MscS (YggB), C-terminal domain | 1 | 1 | |
Protease propeptides/inhibitors | Cadherin-like | 1 | 1 | |