Domain combination pairs in Aegilops tauschii 22

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1800 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	L domain-like	469	79
Protein kinase-like (PK-like)	L domain-like	329	73
L domain-like	L domain-like	297	88
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	295	85
RNI-like	F-box domain	270	23
TRAF domain-like	POZ domain	236	18
RNI-like	L domain-like	201	78
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	134	16
P-loop containing nucleoside triphosphate hydrolases	RNI-like	117	41
Thioredoxin-like	GST C-terminal domain-like	103	8
RNI-like	Protein kinase-like (PK-like)	101	42
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	83	15
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	77	34
RNA-binding domain, RBD	RNA-binding domain, RBD	75	25
Barwin-like endoglucanases	PHL pollen allergen	67	3
Actin-like ATPase domain	Actin-like ATPase domain	66	17
P-loop containing nucleoside triphosphate hydrolases	ABC transporter transmembrane region	65	20
Thiolase-like	Thiolase-like	65	4
EGF/Laminin	Protein kinase-like (PK-like)	63	10
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	56	25
RNI-like	RNI-like	54	33
ABC transporter transmembrane region	ABC transporter transmembrane region	54	14
TPR-like	TPR-like	52	22
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	51	6
Cupredoxins	Cupredoxins	50	12
GroES-like	NAD(P)-binding Rossmann-fold domains	49	11
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	47	11
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	46	5
RING/U-box	RING/U-box	43	22
HAD-like	Calcium ATPase, transmembrane domain M	43	20
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	42	9
ARM repeat	ARM repeat	41	25
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	38	8
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	38	17
F-box domain	Galactose oxidase, central domain	37	5
Calcium ATPase, transduction domain A	HAD-like	36	15
Cyclin-like	Cyclin-like	36	11
Protein kinase-like (PK-like)	PapD-like	34	21
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	34	4
POZ domain	Skp1 dimerisation domain-like	33	6
RING/U-box	ARM repeat	32	12
Ankyrin repeat	TPR-like	32	5
F-box domain	L domain-like	31	11
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	29	17
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	29	10
MFS general substrate transporter	MFS general substrate transporter	28	5
Protein kinase-like (PK-like)	EF-hand	28	5
(Trans)glycosidases	Glycosyl hydrolase domain	28	13
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	27	15
Periplasmic binding protein-like I	Periplasmic binding protein-like II	27	6
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	27	10
F-box domain	F-box domain	26	13
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	26	8
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	26	5
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	26	9
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	25	8
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	25	6
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	25	9
Growth factor receptor domain	Protein kinase-like (PK-like)	24	5
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	24	16
Galactose-binding domain-like	(Trans)glycosidases	24	9
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	24	8
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	24	7
Protein kinase-like (PK-like)	RING/U-box	23	10
DNA-binding domain	DNA-binding domain	23	6
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	23	7
Thioredoxin-like	Thioredoxin-like	22	15
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	22	17
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	22	12
GroEL-intermediate domain like	GroEL apical domain-like	21	10
Homeodomain-like	Homeodomain-like	21	13
Voltage-gated potassium channels	cAMP-binding domain-like	20	9
ENTH/VHS domain	GAT-like domain	20	5
PAZ domain	Ribonuclease H-like	20	6
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	20	4
Nucleic acid-binding proteins	Nucleic acid-binding proteins	20	15
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	19	6
GroEL equatorial domain-like	GroEL-intermediate domain like	19	8
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	19	4
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	19	9
Trypsin-like serine proteases	PDZ domain-like	19	5
GroEL equatorial domain-like	GroEL apical domain-like	19	8
Cytochrome P450	Cytochrome P450	18	5
POZ domain	POZ domain	18	10
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	18	6
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	18	6
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	18	2
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	18	9
TRAF domain-like	TRAF domain-like	18	11
Phospholipase D/nuclease	Phospholipase D/nuclease	17	10
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	17	12
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	17	5
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	17	6
Protein kinase-like (PK-like)	WD40 repeat-like	17	14
GroES-like	GroES-like	16	7
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	16	5
L domain-like	Adhesin YadA, collagen-binding domain	15	4
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	15	8
Homeodomain-like	Bet v1-like	15	9
Trypsin-like serine proteases	Trypsin-like serine proteases	15	10
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	15	4
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	15	7
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	15	3
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	15	7
CCCH zinc finger	CCCH zinc finger	15	12
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	15	4
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	14	4
PUA domain-like	SET domain	14	6
F-box domain	Kelch motif	14	6
ARM repeat	Protein kinase-like (PK-like)	14	14
Ankyrin repeat	Ankyrin repeat	14	7
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	13	2
RING/U-box	vWA-like	13	6
dsRNA-binding domain-like	dsRNA-binding domain-like	13	7
PapD-like	WD40 repeat-like	13	10
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	13	6
DNA-binding pseudobarrel domain	CAD & PB1 domains	13	3
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	12	5
ADC-like	Cdc48 domain 2-like	12	3
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	12	5
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	12	8
Galactose-binding domain-like	Galactose-binding domain-like	12	4
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	12	8
HCP-like	TPR-like	12	7
Translation proteins	EF-G C-terminal domain-like	12	8
ADC-like	P-loop containing nucleoside triphosphate hydrolases	12	3
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	12	9
(Trans)glycosidases	(Trans)glycosidases	12	7
CBS-domain pair	CBS-domain pair	12	8
WRKY DNA-binding domain	WRKY DNA-binding domain	12	6
LDH C-terminal domain-like	NAD(P)-binding Rossmann-fold domains	12	4
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	12	8
WD40 repeat-like	WD40 repeat-like	12	6
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	11	8
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	11	7
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	11	5
ACT-like	ACT-like	11	11
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	11	9
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	11	8
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	11	6
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	11	8
Clavaminate synthase-like	Clavaminate synthase-like	11	3
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	11	9
SNARE-like	SNARE fusion complex	11	3
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	11	9
Nucleotidylyl transferase	ValRS/IleRS/LeuRS editing domain	11	5
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	10	6
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	10	6
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	10	8
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	10	4
Clc chloride channel	CBS-domain pair	10	6
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	10	4
EF-G C-terminal domain-like	EF-G C-terminal domain-like	10	6
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	10	7
CheY-like	Homeodomain-like	10	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	10	3
Ribosomal protein S5 domain 2-like	EF-G C-terminal domain-like	10	6
P-loop containing nucleoside triphosphate hydrolases	TPR-like	10	2
F-box domain	Quinoprotein alcohol dehydrogenase-like	10	4
Bet v1-like	Bet v1-like	10	8
RNase III domain-like	dsRNA-binding domain-like	9	5
vWA-like	beta-sandwich domain of Sec23/24	9	7
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	9	2
BRCT domain	BRCT domain	9	8
RCC1/BLIP-II	FYVE/PHD zinc finger	9	7
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	9	2
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	9	4
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	9	5
Translation proteins	Ribosomal protein S5 domain 2-like	9	5
Galactose mutarotase-like	(Trans)glycosidases	9	4
EF-hand	Riboflavin synthase domain-like	9	5
FYVE/PHD zinc finger	FYVE/PHD zinc finger	9	7
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	9	8
Translational machinery components	L30e-like	9	4
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	9	4
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	9	6
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	9	6
Cysteine proteinases	Cysteine proteinases	9	4
Subtilisin-like	PA domain	9	3
UBC-like	RING/U-box	9	6
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	8	7
PLP-dependent transferases	PLP-dependent transferases	8	4
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	8	6
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	8	5
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	8	7
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	8	7
WD40 repeat-like	RING/U-box	8	6
UBA-like	S-adenosyl-L-methionine-dependent methyltransferases	8	3
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	8	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	8	5
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	8	4
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	8	3
Protein kinase-like (PK-like)	KA1-like	8	2
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	8	7
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	8	4
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	8	7
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	8	6
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	8	7
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	8	6
WD40 repeat-like	ARM repeat	8	7
Adenine nucleotide alpha hydrolases-like	RING/U-box	8	4
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	8	5
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	8	6
vWA-like	Helical domain of Sec23/24	8	6
Tubby C-terminal domain-like	F-box domain	8	4
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	8	7
PK beta-barrel domain-like	PK C-terminal domain-like	8	5
RING/U-box	Nucleotide-diphospho-sugar transferases	8	2
Acid proteases	Acid proteases	8	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	8	6
Nucleic acid-binding proteins	Translation proteins SH3-like domain	8	6
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	7	5
GroEL apical domain-like	SAICAR synthase-like	7	3
Zn-finger domain of Sec23/24	vWA-like	7	5
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	7	4
Osmotin, thaumatin-like protein	Protein kinase-like (PK-like)	7	5
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	7	3
RmlC-like cupins	RmlC-like cupins	7	3
PH domain-like	FYVE/PHD zinc finger	7	5
TPR-like	Protein kinase-like (PK-like)	7	4
Homodimeric domain of signal transducing histidine kinase	CheY-like	7	4
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	7	6
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	7	6
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	7	6
E set domains	(Trans)glycosidases	7	5
ARM repeat	Sec7 domain	7	5
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	7	6
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	7	5
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	7	6
P-loop containing nucleoside triphosphate hydrolases	E set domains	7	3
Actin-crosslinking proteins	(Trans)glycosidases	7	3
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	7	5
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	7	3
Cullin homology domain	"Winged helix" DNA-binding domain	7	4
Voltage-gated potassium channels	Ankyrin repeat	7	4
PH domain-like	RCC1/BLIP-II	7	5
EF-hand	EF-hand	7	6
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	7	5
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	7	5
F-box domain	DPP6 N-terminal domain-like	7	3
Ribonuclease H-like	DNA/RNA polymerases	7	5
Heme-dependent peroxidases	Heme-dependent peroxidases	7	1
cAMP-binding domain-like	Ankyrin repeat	7	4
RING/U-box	FYVE/PHD zinc finger	7	6
YhbY-like	YhbY-like	7	7
RING/U-box	Cysteine proteinases	7	4
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	7	4
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	7	5
ClpP/crotonase	ClpP/crotonase	6	4
NAC domain	NAC domain	6	1
Plant lectins/antimicrobial peptides	Lysozyme-like	6	2
Galactose mutarotase-like	Glycosyl hydrolase domain	6	1
BEACH domain	WD40 repeat-like	6	6
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	6	5
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	6	5
Single hybrid motif	CoA-dependent acyltransferases	6	3
t-snare proteins	SNARE fusion complex	6	3
Chromo domain-like	Chromo domain-like	6	5
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	6	3
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	6	3
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	6	2
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	6	4
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	6	4
SNARE fusion complex	SNARE fusion complex	6	3
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	6	6
Group V grass pollen allergen	Group V grass pollen allergen	6	3
Ubiquitin-like	Ubiquitin-like	6	4
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	6	4
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	6	4
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	6	5
PLC-like phosphodiesterases	PLC-like phosphodiesterases	6	6
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	6	5
Enolase N-terminal domain-like	Enolase C-terminal domain-like	6	3
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	6	4
alpha/beta-Hydrolases	alpha/beta-Hydrolases	6	3
DHS-like NAD/FAD-binding domain	Thiamin diphosphate-binding fold (THDP-binding)	6	4
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	6	4
RNI-like	Ribonuclease H-like	6	5
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	6	4
Ribonuclease H-like	Ribonuclease H-like	6	4
PapD-like	PapD-like	6	6
PreATP-grasp domain	Rudiment single hybrid motif	6	5
ARM repeat	Clathrin adaptor appendage domain	6	5
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	6	5
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	6	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	6	5
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	6	6
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	6	5
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	6	6
F-box domain	YWTD domain	6	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	6	4
P-loop containing nucleoside triphosphate hydrolases	PapD-like	6	6
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	6	4
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	6	3
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	6	3
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6	4
Ubiquitin-like	UBA-like	5	5
Cysteine-rich domain	Cysteine-rich domain	5	3
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	5	3
SWIB/MDM2 domain	Plus3-like	5	4
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	5	2
PurM N-terminal domain-like	PurM C-terminal domain-like	5	4
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	5	4
Plus3-like	GYF domain	5	4
SWIB/MDM2 domain	GYF domain	5	4
Nucleotidylyl transferase	Nucleotidylyl transferase	5	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	5	2
HCP-like	HCP-like	5	4
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	5	3
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	5	5
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	5	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	5	3
FAS1 domain	FAS1 domain	5	2
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	5	3
PH domain-like	BEACH domain	5	5
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	5	3
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	5	4
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	5	4
Acid proteases	Saposin	5	3
ARM repeat	Hect, E3 ligase catalytic domain	5	3
RING/U-box	TPR-like	5	5
L domain-like	PapD-like	5	5
Thioredoxin-like	Ubiquitin-like	5	5
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	5	3
Chaperone J-domain	Chaperone J-domain	5	3
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	5	4
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	5	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	5	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	5	2
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	5	4
Cysteine proteinases	Granulin repeat	5	3
beta-beta-alpha zinc fingers	P-loop containing nucleoside triphosphate hydrolases	5	5
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	5	3
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	5	5
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	5	3
F-box domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	5	3
Protein kinase-like (PK-like)	Ribonuclease H-like	5	5
EF-hand	P-loop containing nucleoside triphosphate hydrolases	5	3
Actin depolymerizing proteins	Actin depolymerizing proteins	5	5
P-loop containing nucleoside triphosphate hydrolases	TGS-like	5	2
Agglutinin	Aerolisin/ETX pore-forming domain	5	4
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	5	3
PH domain-like	WD40 repeat-like	5	5
CBS-domain pair	CAD & PB1 domains	5	4
Cullin repeat-like	Cullin homology domain	5	3
Nucleotidylyl transferase	Ribosomal protein L25-like	5	5
Ricin B-like lectins	Ricin B-like lectins	5	3
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	5	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	5	3
Flavoproteins	Riboflavin synthase domain-like	5	3
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	5	2
beta-beta-alpha zinc fingers	L domain-like	5	5
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	5	1
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	5	4
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	5	4
Cullin repeat-like	"Winged helix" DNA-binding domain	5	3
FKBP-like	TPR-like	5	3
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	5	2
WW domain	WW domain	5	4
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	5	3
E set domains	Ankyrin repeat	5	1
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	4	3
FYVE/PHD zinc finger	Plus3-like	4	3
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	4	3
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	4	4
Translation proteins	ThrRS/AlaRS common domain	4	2
PAZ domain	RNase III domain-like	4	3
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	4	3
CAD & PB1 domains	Protein kinase-like (PK-like)	4	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	4	1
RNA-binding domain, RBD	CCCH zinc finger	4	4
HD-domain/PDEase-like	Nucleotidyltransferase	4	3
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	4	3
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	4	4
Nucleoside hydrolase	Nucleoside hydrolase	4	3
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	4	3
NAD(P)-binding Rossmann-fold domains	ACT-like	4	3
F-box domain	WD40 repeat-like	4	4
HMA, heavy metal-associated domain	HAD-like	4	4
F-box domain	3-carboxy-cis,cis-mucoante lactonizing enzyme	4	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	4	2
FYVE/PHD zinc finger	SWIB/MDM2 domain	4	3
Starch-binding domain-like	Galactose-binding domain-like	4	4
PreATP-grasp domain	Single hybrid motif	4	3
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	4	2
Aconitase iron-sulfur domain	LeuD/IlvD-like	4	3
FYVE/PHD zinc finger	SET domain	4	4
FYVE/PHD zinc finger	GYF domain	4	3
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	4	2
PAZ domain	dsRNA-binding domain-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	4	1
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	4	3
Voltage-gated potassium channels	Voltage-gated potassium channels	4	4
NTF2-like	RNA-binding domain, RBD	4	2
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	4	4
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	4	4
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	4
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	4	3
FKBP-like	FKBP-like	4	2
F-box domain	Retrovirus zinc finger-like domains	4	3
E set domains	Glycosyl hydrolase domain	4	4
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	4	1
Protein kinase-like (PK-like)	Clavaminate synthase-like	4	4
Saposin	Saposin	4	2
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin	4	2
PA domain	Zn-dependent exopeptidases	4	4
Ankyrin repeat	Protein kinase-like (PK-like)	4	3
XPC-binding domain	UBA-like	4	4
ARM repeat	Subdomain of clathrin and coatomer appendage domain	4	4
Translation proteins	Initiation factor IF2/eIF5b, domain 3	4	3
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	4	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	4	4
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	4	2
UBA-like	UBA-like	4	4
TPR-like	Chaperone J-domain	4	4
Serpins	Serpins	4	3
RNase III domain-like	RNase III domain-like	4	3
SAP domain	FYVE/PHD zinc finger	4	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	4	4
P-loop containing nucleoside triphosphate hydrolases	ARM repeat	4	4
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
Bowman-Birk inhibitor, BBI	Bowman-Birk inhibitor, BBI	4	2
ISP domain	Bet v1-like	4	4
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	4	2
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
POZ domain	Ankyrin repeat	4	4
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	4	2
Rudiment single hybrid motif	Single hybrid motif	4	3
Lysozyme-like	Protein kinase-like (PK-like)	4	2
Ubiquitin-like	BAG domain	4	3
FYVE/PHD zinc finger	Homeodomain-like	4	4
Protein kinase-like (PK-like)	vWA-like	4	3
Pectin lyase-like	Pectin lyase-like	4	1
(Trans)glycosidases	Ricin B-like lectins	4	3
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	4	3
ACT-like	Protein kinase-like (PK-like)	4	2
RING/U-box	TRAF domain-like	4	3
Oxidoreductase molybdopterin-binding domain	E set domains	4	4
P-loop containing nucleoside triphosphate hydrolases	DNase I-like	4	4
RNI-like	ARM repeat	3	2
Chaperone J-domain	4Fe-4S ferredoxins	3	3
RING/U-box	BRCT domain	3	2
GINS helical bundle-like	PriA/YqbF domain	3	3
PreATP-grasp domain	ClpP/crotonase	3	2
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	3	2
GroEL-intermediate domain like	GroEL-intermediate domain like	3	3
Flavoproteins	Flavoproteins	3	2
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	3	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	3	3
Periplasmic binding protein-like II	ACT-like	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	3	3
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	3	2
Ubiquitin-like	Homeodomain-like	3	2
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	3	2
TATA-box binding protein-like	TATA-box binding protein-like	3	2
Sec63 N-terminal domain-like	E set domains	3	3
beta-beta-alpha zinc fingers	RNI-like	3	3
FAD-binding/transporter-associated domain-like	FAD-binding/transporter-associated domain-like	3	3
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	3	2
Kelch motif	Metallo-dependent phosphatases	3	2
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	3	1
Plant lectins/antimicrobial peptides	Plant lectins/antimicrobial peptides	3	3
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	3	3
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	3	2
EGF/Laminin	Growth factor receptor domain	3	2
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	3	2
WGR domain-like	ADP-ribosylation	3	3
Zinc beta-ribbon	Zinc beta-ribbon	3	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	3	1
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	3	3
Ubiquitin-like	XPC-binding domain	3	3
PH domain-like	PH domain-like	3	3
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	3	3
NAD(P)-linked oxidoreductase	NAD(P)-linked oxidoreductase	3	2
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	3	2
Carbamate kinase-like	ACT-like	3	3
Six-hairpin glycosidases	Six-hairpin glycosidases	3	2
PRTase-like	PRTase-like	3	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	3	2
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	3	3
DNase I-like	DNase I-like	3	1
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	3	3
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	3
Oxysterol-binding protein-like	Oxysterol-binding protein-like	3	2
Homeodomain-like	FAD-linked reductases, C-terminal domain	3	3
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	3	3
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	3	2
Concanavalin A-like lectins/glucanases	PH domain-like	3	3
YrdC/RibB	RibA-like	3	3
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	3	2
L domain-like	DNase I-like	3	3
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
PurS-like	PurM N-terminal domain-like	3	2
P-loop containing nucleoside triphosphate hydrolases	Kelch motif	3	2
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	3	3
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	3	3
Dom34/Pelota N-terminal domain-like	Translational machinery components	3	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	3	3
Homeodomain-like	FAD/NAD(P)-binding domain	3	3
LEA14-like	LEA14-like	3	3
RNA-binding domain, RBD	PABC (PABP) domain	3	3
Clavaminate synthase-like	F-box domain	3	3
Rudiment single hybrid motif	ClpP/crotonase	3	2
PurS-like	FGAM synthase PurL, linker domain	3	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	3	1
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	3	3
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	3	2
PH domain-like	Bet v1-like	3	2
ARM repeat	Tudor/PWWP/MBT	3	3
CHY zinc finger-like	Zinc hairpin stack	3	3
L domain-like	Kelch motif	3	2
P-loop containing nucleoside triphosphate hydrolases	WRKY DNA-binding domain	3	2
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	3	2
TRAF domain-like	Cysteine proteinases	3	2
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	3	3
tRNA-binding arm	Class II aaRS and biotin synthetases	3	3
PLP-binding barrel	Alanine racemase C-terminal domain-like	3	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	3	2
Concanavalin A-like lectins/glucanases	WD40 repeat-like	3	3
E set domains	AMPKBI-like	3	3
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	3	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	3	2
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	3	3
BAR/IMD domain-like	SH3-domain	3	3
Ribonuclease H-like	HRDC-like	3	2
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	3	2
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	3
P-loop containing nucleoside triphosphate hydrolases	Ribonuclease H-like	3	3
Concanavalin A-like lectins/glucanases	BEACH domain	3	3
Serine metabolism enzymes domain	ACT-like	3	2
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	2
Galactose oxidase, central domain	E set domains	3	2
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	3	3
Annexin	Annexin	3	1
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	3	2
TPR-like	CAD & PB1 domains	3	3
Zinc hairpin stack	RING/U-box	3	3
L domain-like	Thioredoxin-like	3	3
FAD/NAD(P)-binding domain	EF-hand	3	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	3	3
Protein kinase-like (PK-like)	C2 domain (Calcium/lipid-binding domain, CaLB)	3	2
Retrovirus zinc finger-like domains	RING/U-box	3	3
Mannose-binding lectins	Mannose-binding lectins	3	3
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	3	2
P-loop containing nucleoside triphosphate hydrolases	Mannose-binding lectins	3	3
GAF domain-like	CheY-like	3	2
PurM N-terminal domain-like	PurM N-terminal domain-like	3	2
Class II aaRS ABD-related	C-terminal domain of ProRS	3	2
SWIB/MDM2 domain	SWIB/MDM2 domain	3	2
BRCT domain	FYVE/PHD zinc finger	3	3
Dom34/Pelota N-terminal domain-like	L30e-like	3	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	3	3
Thioredoxin-like	P-loop containing nucleoside triphosphate hydrolases	3	3
Tudor/PWWP/MBT	SET domain	3	3
Protease propeptides/inhibitors	Subtilisin-like	3	2
Ubiquitin-like	Cysteine proteinases	3	3
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	3	3
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	3	1
Single hybrid motif	ClpP/crotonase	3	2
PurS-like	PurM C-terminal domain-like	3	2
CCCH zinc finger	RING/U-box	3	3
TPR-like	Thioredoxin-like	3	2
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	3
WD40 repeat-like	DNase I-like	3	3
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	3	3
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	3
Subtilisin-like	Subtilisin-like	3	2
DNA/RNA polymerases	Protein kinase-like (PK-like)	3	3
Ribonuclease H-like	MFS general substrate transporter	3	3
PurM C-terminal domain-like	PurM C-terminal domain-like	3	2
Ribosomal protein L6	Ribosomal protein L6	3	3
UBC-like	Phosphoenolpyruvate/pyruvate domain	3	2
E set domains	Riboflavin synthase domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	3	2
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	3	3
beta-beta-alpha zinc fingers	Ribonuclease H-like	3	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	3	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	3	3
UBC-like	UBC-like	3	2
Chlorophyll a-b binding protein	Chlorophyll a-b binding protein	3	2
FAD/NAD(P)-binding domain	Nucleotide-binding domain	3	3
L domain-like	WRKY DNA-binding domain	3	2
RCC1/BLIP-II	RCC1/BLIP-II	3	3
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	3	2
Cyclophilin-like	RNA-binding domain, RBD	3	3
PurS-like	Class I glutamine amidotransferase-like	3	2
Class II aaRS and biotin synthetases	Translation proteins	3	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	3	2
F-box domain	NHL repeat	3	3
Tudor/PWWP/MBT	FYVE/PHD zinc finger	3	3
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	3	2
Putative DNA-binding domain	PheT/TilS domain	2	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	2	1
PR-1-like	Protein kinase-like (PK-like)	2	2
F-box domain	NTF2-like	2	2
PH domain-like	HMG-box	2	1
PreATP-grasp domain	PreATP-grasp domain	2	2
PH domain-like	Ankyrin repeat	2	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	2	2
GST C-terminal domain-like	Ribosomal protein L25-like	2	2
6-phosphogluconate dehydrogenase C-terminal domain-like	Aldolase	2	2
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	2	1
F-box domain	NAD(P)-binding Rossmann-fold domains	2	2
DNA-binding domain	P-loop containing nucleoside triphosphate hydrolases	2	2
FYVE/PHD zinc finger	Chromo domain-like	2	2
TAZ domain	TAZ domain	2	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	2	1
cAMP-binding domain-like	cAMP-binding domain-like	2	2
Kelch motif	DNA/RNA polymerases	2	2
Nucleotidylyl transferase	tRNA-binding arm	2	2
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	2	2
Zinc beta-ribbon	Cyclin-like	2	2
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	2	2
STI-like	STI-like	2	2
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
RNA-binding domain, RBD	Surp module (SWAP domain)	2	1
Galactose-binding domain-like	NAD(P)-binding Rossmann-fold domains	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	2	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	2	2
Staphylococcal nuclease	Staphylococcal nuclease	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	2
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
Putative DNA-binding domain	Class II aaRS and biotin synthetases	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	2
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	2	1
PH domain-like	GTPase activation domain, GAP	2	1
DNA-glycosylase	DNA-glycosylase	2	2
Concanavalin A-like lectins/glucanases	Nucleotide-diphospho-sugar transferases	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	2	1
F-box domain	DNA-binding pseudobarrel domain	2	2
Ribonuclease H-like	WD40 repeat-like	2	2
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	2	2
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Clc chloride channel	Clc chloride channel	2	2
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
Chaperone J-domain	Thioredoxin-like	2	2
L domain-like	NAD(P)-binding Rossmann-fold domains	2	2
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	2	2
Nucleotide-diphospho-sugar transferases	ARM repeat	2	2
GYF domain	SET domain	2	2
ARID-like	HSP20-like chaperones	2	2
Protein kinase-like (PK-like)	DNase I-like	2	2
PUA domain-like	Nucleotidylyl transferase	2	2
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	2	2
RNA-binding domain, RBD	DPP6 N-terminal domain-like	2	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	2	2
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	2	2
Nucleotidyltransferase	Nucleotidyltransferase	2	2
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	2	2
ArfGap/RecO-like zinc finger	Ankyrin repeat	2	2
Protein kinase-like (PK-like)	F-box domain	2	2
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	2	1
Starch-binding domain-like	Starch-binding domain-like	2	2
PP2C-like	PP2C-like	2	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	1
ALDH-like	ALDH-like	2	1
PRTase-like	Ribulose-phoshate binding barrel	2	2
PH domain-like	Protein kinase-like (PK-like)	2	2
Amine oxidase N-terminal region	Amine oxidase N-terminal region	2	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	2	2
Arp2/3 complex subunits	Arp2/3 complex subunits	2	2
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	2	1
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	2
F-box domain	RNA-binding domain, RBD	2	1
UROD/MetE-like	UROD/MetE-like	2	1
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	2	2
vWA-like	SPOC domain-like	2	2
Ribosomal protein S5 domain 2-like	RNA-binding domain, RBD	2	2
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	2	2
Ribosomal protein L19 (L19e)	Ribosomal protein L19 (L19e)	2	1
Protein kinase-like (PK-like)	Mannose-binding lectins	2	2
SBT domain	Ankyrin repeat	2	1
Amidase signature (AS) enzymes	TPR-like	2	1
Protein kinase-like (PK-like)	PP2C-like	2	2
Thioredoxin-like	eEF1-gamma domain	2	2
HAD-like	BRCT domain	2	2
Thioredoxin-like	Cysteine-rich domain	2	2
Tryptophan synthase beta subunit-like PLP-dependent enzymes	Tryptophan synthase beta subunit-like PLP-dependent enzymes	2	2
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	2	1
Aquaporin-like	Aquaporin-like	2	2
Starch-binding domain-like	Phosphoglycerate mutase-like	2	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	2	1
HAD-like	HAD-like	2	2
PA domain	RING/U-box	2	2
HAD-like	DNA/RNA polymerases	2	2
GAF domain-like	GAF domain-like	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	2	2
PYP-like sensor domain (PAS domain)	F-box domain	2	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	2	2
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	2	2
Homeodomain-like	UBC-like	2	2
RNI-like	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	2	2
Surp module (SWAP domain)	ENTH/VHS domain	2	1
SAP domain	RNA-binding domain, RBD	2	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	2	1
Pseudouridine synthase	Pseudouridine synthase	2	2
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	2	2
SET domain	HIT/MYND zinc finger-like	2	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	2
Ribosomal protein S5 domain 2-like	F-box domain	2	2
ARM repeat	DNase I-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	2	2
GST C-terminal domain-like	eEF1-gamma domain	2	2
Clathrin heavy-chain terminal domain	ARM repeat	2	2
L9 N-domain-like	Ribosomal protein L9 C-domain	2	1
Methylglyoxal synthase-like	Cytidine deaminase-like	2	2
Nucleic acid-binding proteins	Protein kinase-like (PK-like)	2	2
NAD(P)-binding Rossmann-fold domains	Citrate synthase	2	2
Calcium ATPase, transduction domain A	DNA/RNA polymerases	2	2
F-box domain	P-loop containing nucleoside triphosphate hydrolases	2	2
Glutamine synthetase/guanido kinase	GatB/YqeY motif	2	1
F-box domain	ARM repeat	2	2
Staphylococcal nuclease	Tudor/PWWP/MBT	2	2
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	2	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	2	2
NAD(P)-binding Rossmann-fold domains	Aldolase	2	2
HIT/MYND zinc finger-like	Cysteine proteinases	2	2
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	2	2
PLC-like phosphodiesterases	EF-hand	2	2
BAR/IMD domain-like	Ankyrin repeat	2	2
GST C-terminal domain-like	Nucleotidylyl transferase	2	2
eIF-2-alpha, C-terminal domain	eIF-2-alpha, C-terminal domain	2	2
HAD-like	dsRNA-binding domain-like	2	1
(Phosphotyrosine protein) phosphatases II	E set domains	2	2
WD40 repeat-like	Bromodomain	2	2
Carbamate kinase-like	ALDH-like	2	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	2	2
GroEL equatorial domain-like	GroEL equatorial domain-like	2	2
FF domain	FF domain	2	2
Galactose mutarotase-like	Galactose-binding domain-like	2	2
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	2	1
Ankyrin repeat	RNA-binding domain, RBD	2	2
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
"Winged helix" DNA-binding domain	HRDC-like	2	2
PH domain-like	Oxysterol-binding protein-like	2	2
Zn-dependent exopeptidases	Zn-dependent exopeptidases	2	2
F-box domain	Tricorn protease domain 2	2	2
PYP-like sensor domain (PAS domain)	GAF domain-like	2	2
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	2
L domain-like	Mannose-binding lectins	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	2	2
TAZ domain	RING/U-box	2	2
Ribonuclease H-like	TPR-like	2	2
BRCT domain	WGR domain-like	2	2
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	2	1
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	2
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	2	2
Nucleic acid-binding proteins	eIF2alpha middle domain-like	2	2
Carbamate kinase-like	Carbamate kinase-like	2	2
Pseudouridine synthase	PUA domain-like	2	2
RING/U-box	Ran binding protein zinc finger-like	2	1
RCC1/BLIP-II	Protein kinase-like (PK-like)	2	2
F-box domain	POZ domain	2	2
Protein kinase-like (PK-like)	Quinoprotein alcohol dehydrogenase-like	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	2	1
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	2	2
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F-box domain	2	2
DNA/RNA polymerases	L domain-like	2	2
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	2	2
GST C-terminal domain-like	GST C-terminal domain-like	2	2
NTF2-like	RNI-like	2	2
Kelch motif	Galactose oxidase, central domain	2	2
Acetyl-CoA synthetase-like	ACP-like	2	1
Clavaminate synthase-like	beta-beta-alpha zinc fingers	2	2
Tropomyosin	Tropomyosin	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	2	2
PAH2 domain	PAH2 domain	2	2
NTF2-like	NTF2-like	2	2
EF-hand	Mitochondrial carrier	2	2
Macro domain-like	Zn-dependent exopeptidases	2	2
PH domain-like	ArfGap/RecO-like zinc finger	2	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	2	2
CHY zinc finger-like	RING/U-box	2	2
ARM repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	1
Cyclophilin-like	TPR-like	2	1
TAZ domain	FYVE/PHD zinc finger	2	2
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	2	1
PA domain	Transferrin receptor-like dimerisation domain	2	2
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	2	1
Ricin B-like lectins	Glycosyl hydrolase domain	2	1
Ribulose-phoshate binding barrel	P-loop containing nucleoside triphosphate hydrolases	2	2
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	2	1
PheT/TilS domain	Class II aaRS and biotin synthetases	2	2
Class II aaRS and biotin synthetases	Class II aaRS and biotin synthetases	2	2
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	2
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	2	2
WD40 repeat-like	L domain-like	2	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	2	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	2	1
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	2	2
DNA/RNA polymerases	Calcium ATPase, transmembrane domain M	2	2
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	2	2
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	2	2
F-box domain	Calcium-dependent phosphotriesterase	2	2
Translation proteins SH3-like domain	Translation proteins SH3-like domain	2	2
F-box domain	SET domain	2	2
Kelch motif	Kelch motif	2	2
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	2	2
Homeodomain-like	"Winged helix" DNA-binding domain	2	2
Protein kinase-like (PK-like)	Cysteine proteinases	2	2
BAR/IMD domain-like	PH domain-like	2	2
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
"Winged helix" DNA-binding domain	E set domains	2	2
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	2	1
RING/U-box	Homeodomain-like	2	2
Barwin-like endoglucanases	Barwin-like endoglucanases	2	2
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	2	2
L domain-like	Ribonuclease H-like	2	2
Citrate synthase	Homeodomain-like	2	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	2	2
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Radical SAM enzymes	Radical SAM enzymes	2	2
PRP4-like	WD40 repeat-like	2	1
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	2	2
ENT-like	Tudor/PWWP/MBT	2	2
Ankyrin repeat	RING/U-box	2	2
TPR-like	WD40 repeat-like	2	2
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	2
Sec1/munc18-like (SM) proteins	Sec1/munc18-like (SM) proteins	2	2
Cullin repeat-like	Cullin repeat-like	2	2
RNA-binding domain, RBD	ENTH/VHS domain	2	1
HSP90 C-terminal domain	F-box domain	2	2
PRP4-like	Functional domain of the splicing factor Prp18	2	2
RL5-like	Cytochrome c oxidase subunit III-like	2	2
SNARE-like	Domain of the SRP/SRP receptor G-proteins	2	1
Tricorn protease N-terminal domain	alpha/beta-Hydrolases	2	2
ACP-like	Quinoprotein alcohol dehydrogenase-like	2	1
HAD-like	NTF2-like	2	2
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	2	2
ARM repeat	POZ domain	2	2
TPR-like	"Winged helix" DNA-binding domain	2	2
WW domain	FF domain	2	2
Taf5 N-terminal domain-like	WD40 repeat-like	2	2
Ankyrin repeat	Ribonuclease H-like	2	2
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	2	1
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	2	1
Agglutinin	Agglutinin	2	2
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	2	2
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	2
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
NAC domain	Protein kinase-like (PK-like)	1	1
F-box domain	NAC domain	1	1
Protein kinase-like (PK-like)	Peptidase/esterase 'gauge' domain	1	1
Retrovirus zinc finger-like domains	POZ domain	1	1
Translation proteins	Translation proteins	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
Tim10-like	Glycosyl hydrolase domain	1	1
Adenine nucleotide alpha hydrolases-like	FKBP-like	1	1
Concanavalin A-like lectins/glucanases	F-box domain	1	1
Bacterial hemolysins	Apolipoprotein A-I	1	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	1	1
RNI-like	Rubredoxin-like	1	1
L domain-like	Arp2/3 complex 21 kDa subunit ARPC3	1	1
PLC-like phosphodiesterases	Mitochondrial carrier	1	1
Plant invertase/pectin methylesterase inhibitor	Plant invertase/pectin methylesterase inhibitor	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
PIN domain-like	Chromo domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Glutamyl tRNA-reductase dimerization domain	1	1
Protein kinase-like (PK-like)	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
MFS general substrate transporter	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Subtilisin-like	Ribonuclease H-like	1	1
(Trans)glycosidases	FAD/NAD(P)-binding domain	1	1
Activating enzymes of the ubiquitin-like proteins	Ribonuclease H-like	1	1
Ubiquitin-like	Ankyrin repeat	1	1
(Trans)glycosidases	Chitinase insertion domain	1	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	1	1
RING/U-box	Mog1p/PsbP-like	1	1
RuBisCO, large subunit, small (N-terminal) domain	RuBisCo, C-terminal domain	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
Lesion bypass DNA polymerase (Y-family), little finger domain	Calcium ATPase, transmembrane domain M	1	1
FAD/NAD(P)-binding domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	1	1
DNA-binding pseudobarrel domain	Protein kinase-like (PK-like)	1	1
ADC synthase	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
alpha-D-mannose-specific plant lectins	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Translation proteins	PRC-barrel domain	1	1
HLH, helix-loop-helix DNA-binding domain	Aconitase iron-sulfur domain	1	1
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	1	1
MFS general substrate transporter	DNase I-like	1	1
HSP90 C-terminal domain	L domain-like	1	1
POZ domain	Pentapeptide repeat-like	1	1
DNA/RNA polymerases	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
Cysteine proteinases	Mannose-binding lectins	1	1
Thiamin pyrophosphokinase, catalytic domain	Glycerol-3-phosphate (1)-acyltransferase	1	1
Tudor/PWWP/MBT	Protein kinase-like (PK-like)	1	1
SMI1/KNR4-like	ApaG-like	1	1
Nucleotidyltransferase	EF-hand	1	1
Metallo-dependent phosphatases	DNA/RNA polymerases	1	1
Retrovirus zinc finger-like domains	ABC transporter transmembrane region	1	1
Voltage-gated potassium channels	EF-hand	1	1
GroEL-intermediate domain like	SAICAR synthase-like	1	1
MTH938-like	Phosphoenolpyruvate/pyruvate domain	1	1
Homeodomain-like	Nucleotide-binding domain	1	1
Prokaryotic ribosomal protein L17	RibA-like	1	1
PapD-like	Ankyrin repeat	1	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Lipoxigenase	Lipoxigenase	1	1
PAZ domain	Ubiquitin-like	1	1
Ypt/Rab-GAP domain of gyp1p	RNA-binding domain, RBD	1	1
Ribonuclease H-like	GAT-like domain	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
ABC transporter transmembrane region	DNA/RNA polymerases	1	1
C-terminal domain of alpha and beta subunits of F1 ATP synthase	Epsilon subunit of F1F0-ATP synthase N-terminal domain	1	1
Integrin alpha N-terminal domain	Integrin alpha N-terminal domain	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Ribonuclease H-like	PLP-dependent transferases	1	1
L domain-like	DNA-binding domain	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
TPR-like	SET domain	1	1
RNI-like	Mannose-binding lectins	1	1
Granulin repeat	Mannose-binding lectins	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
PYP-like sensor domain (PAS domain)	CheY-like	1	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	1	1
Nucleotidylyl transferase	DNA-binding pseudobarrel domain	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	1	1
SET domain	ABC transporter transmembrane region	1	1
GroEL-intermediate domain like	DNA-binding domain	1	1
Ran binding protein zinc finger-like	Translation proteins	1	1
EF-hand	MFS general substrate transporter	1	1
Galactose oxidase, central domain	Retrovirus zinc finger-like domains	1	1
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleic acid-binding proteins	Ribulose-phoshate binding barrel	1	1
LysM domain	Protein kinase-like (PK-like)	1	1
DNA-glycosylase	Nudix	1	1
RNI-like	PapD-like	1	1
RING/U-box	UBA-like	1	1
Cysteine alpha-hairpin motif	Mitochondrial carrier	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
Ribosomal protein S5 domain 2-like	E set domains	1	1
PDZ domain-like	PDZ domain-like	1	1
MFS general substrate transporter	Aldolase	1	1
BRCA2 tower domain	HAD-like	1	1
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Ubiquitin-like	Protein kinase-like (PK-like)	1	1
ARM repeat	BEACH domain	1	1
Tropomyosin	Smc hinge domain	1	1
PX domain	EreA/ChaN-like	1	1
EF-hand	alpha/beta-Hydrolases	1	1
Amine oxidase N-terminal region	Amine oxidase catalytic domain	1	1
MFS general substrate transporter	PRTase-like	1	1
Glycosyl hydrolase domain	Phospholipase D/nuclease	1	1
Tubulin nucleotide-binding domain-like	Tubulin nucleotide-binding domain-like	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
YjeF N-terminal domain-like	FMN-binding split barrel	1	1
RING/U-box	RNA-binding domain, RBD	1	1
Cyclophilin-like	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin	1	1
PX domain	BAR/IMD domain-like	1	1
Ribonuclease H-like	F-box domain	1	1
NAD-binding domain of HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	1	1
L domain-like	Arginase/deacetylase	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
Class II aaRS and biotin synthetases	RNI-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Flavoproteins	1	1
Protein kinase-like (PK-like)	alpha/beta knot	1	1
HD-domain/PDEase-like	TGS-like	1	1
L domain-like	Phage fibre proteins	1	1
Ribosomal protein S5 domain 2-like	DNA/RNA polymerases	1	1
Galactose mutarotase-like	Starch-binding domain-like	1	1
Lesion bypass DNA polymerase (Y-family), little finger domain	Calcium ATPase, transduction domain A	1	1
Clavaminate synthase-like	RING/U-box	1	1
Lysozyme-like	Lysozyme-like	1	1
SNARE-like	NAD(P)-binding Rossmann-fold domains	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
MFS general substrate transporter	DNA/RNA polymerases	1	1
all-alpha NTP pyrophosphatases	all-alpha NTP pyrophosphatases	1	1
UBC-like	DNase I-like	1	1
L domain-like	POZ domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
alpha/beta-Hydrolases	Glycerol-3-phosphate (1)-acyltransferase	1	1
L domain-like	FAD/NAD(P)-binding domain	1	1
PA domain	Ribonuclease H-like	1	1
Thiolase-like	Clavaminate synthase-like	1	1
RNI-like	DNA-binding pseudobarrel domain	1	1
Ribonuclease H-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Heme oxygenase-like	HAD-like	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	Terpenoid synthases	1	1
ARM repeat	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	1	1
E set domains	CBS-domain pair	1	1
SNARE-like	TPR-like	1	1
4Fe-4S ferredoxins	Metallo-hydrolase/oxidoreductase	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
Ribonuclease H-like	Terpenoid synthases	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	DNA-binding pseudobarrel domain	1	1
DNA-binding pseudobarrel domain	PapD-like	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
Ribonuclease H-like	ADP-ribosylation	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
RING/U-box	Nucleotidyltransferase	1	1
Cysteine proteinases	UBA-like	1	1
Restriction endonuclease-like	RuvA domain 2-like	1	1
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
alpha/beta-Hydrolases	RNI-like	1	1
PP2C-like	cAMP-binding domain-like	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
Terpenoid synthases	Multidrug resistance efflux transporter EmrE	1	1
ADP-ribosylation	DNA/RNA polymerases	1	1
HD-domain/PDEase-like	EF-hand	1	1
Glutathione synthetase ATP-binding domain-like	4Fe-4S ferredoxins	1	1
Alpha-L RNA-binding motif	Pseudouridine synthase	1	1
Arp2/3 complex 21 kDa subunit ARPC3	Arp2/3 complex 21 kDa subunit ARPC3	1	1
F-box domain	TRAF domain-like	1	1
RNA-binding domain, RBD	Ribosome inactivating proteins (RIP)	1	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
F1F0 ATP synthase subunit A	F1F0 ATP synthase subunit C	1	1
Ubiquitin-like	Cap-Gly domain	1	1
Ribulose-phoshate binding barrel	L domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
RING/U-box	PAP/OAS1 substrate-binding domain	1	1
Formin homology 2 domain (FH2 domain)	Macro domain-like	1	1
POZ domain	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	1	1
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	1	1
Prokaryotic ribosomal protein L17	TPR-like	1	1
SET domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Histone-fold	alpha-D-mannose-specific plant lectins	1	1
L9 N-domain-like	WD40 repeat-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
ISP transmembrane anchor	ISP domain	1	1
Cytochrome f, large domain	Photosystem II antenna protein-like	1	1
(Phosphotyrosine protein) phosphatases II	Zn-dependent exopeptidases	1	1
Cysteine proteinases	NAD(P)-binding Rossmann-fold domains	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Lesion bypass DNA polymerase (Y-family), little finger domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
P-loop containing nucleoside triphosphate hydrolases	LuxS/MPP-like metallohydrolase	1	1
ARM repeat	UBA-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
E set domains	Cytochrome b5-like heme/steroid binding domain	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	1	1
Ribosomal protein L25-like	Ribosomal protein L25-like	1	1
Trigger factor ribosome-binding domain	FKBP-like	1	1
RNA-binding domain, RBD	Osmotin, thaumatin-like protein	1	1
P-loop containing nucleoside triphosphate hydrolases	GIY-YIG endonuclease	1	1
P-loop containing nucleoside triphosphate hydrolases	HIT-like	1	1
Translation proteins SH3-like domain	NAD(P)-linked oxidoreductase	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	1	1
HCP-like	WD40 repeat-like	1	1
Prokaryotic ribosomal protein L17	YrdC/RibB	1	1
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	1	1
SIS domain	SIS domain	1	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
Tudor/PWWP/MBT	ABC transporter transmembrane region	1	1
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	1	1
TRAF domain-like	Retrovirus zinc finger-like domains	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
(Trans)glycosidases	Aquaporin-like	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
Homeodomain-like	L domain-like	1	1
GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	1	1
Acyl-CoA binding protein	Galactose oxidase, central domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	TPR-like	1	1
Ribosomal protein L30p/L7e	Ribosomal protein L30p/L7e	1	1
Thioredoxin-like	Trypsin-like serine proteases	1	1
HisI-like	all-alpha NTP pyrophosphatases	1	1
POZ domain	WD40 repeat-like	1	1
Arabinanase/levansucrase/invertase	DNA/RNA polymerases	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
Terpenoid synthases	Protein kinase-like (PK-like)	1	1
Aldolase	Aldolase	1	1
RCC1/BLIP-II	Mitochondrial carrier	1	1
C-terminal, gelsolin-like domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
MFS general substrate transporter	Protein kinase-like (PK-like)	1	1
FAD/NAD(P)-binding domain	Adenine nucleotide alpha hydrolases-like	1	1
Galactose-binding domain-like	ARM repeat	1	1
MFS general substrate transporter	HAD-like	1	1
Galactose-binding domain-like	Homeodomain-like	1	1
Transmembrane di-heme cytochromes	a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	1	1
Protein kinase-like (PK-like)	FtsH protease domain-like	1	1
Heme-dependent peroxidases	Actin-like ATPase domain	1	1
Macro domain-like	HIT-like	1	1
Ribosomal protein L13	HCP-like	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
DNA/RNA polymerases	PapD-like	1	1
POZ domain	TAZ domain	1	1
PUA domain-like	Ribosomal protein S5 domain 2-like	1	1
ARM repeat	DNA/RNA polymerases	1	1
DNA-binding pseudobarrel domain	POZ domain	1	1
FAD/NAD(P)-binding domain	Protein kinase-like (PK-like)	1	1
Histidine-containing phosphotransfer domain, HPT domain	Histidine-containing phosphotransfer domain, HPT domain	1	1
Urease, gamma-subunit	Urease, beta-subunit	1	1
Protein kinase-like (PK-like)	Formin homology 2 domain (FH2 domain)	1	1
GAT-like domain	GAT-like domain	1	1
Ubiquitin-like	Trypsin-like serine proteases	1	1
Mog1p/PsbP-like	EF-hand	1	1
RNI-like	Concanavalin A-like lectins/glucanases	1	1
SNARE fusion complex	Protein kinase-like (PK-like)	1	1
Class I glutamine amidotransferase-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
DNA-binding pseudobarrel domain	Mannose-binding lectins	1	1
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	1	1
Ribonuclease H-like	vWA-like	1	1
Outer arm dynein light chain 1	Protein kinase-like (PK-like)	1	1
VPS28 C-terminal domain-like	L domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Chaperone J-domain	1	1
alpha/beta knot	alpha/beta knot	1	1
NAD(P)-binding Rossmann-fold domains	DNA/RNA polymerases	1	1
DNA/RNA polymerases	YhbY-like	1	1
F-box domain	HCP-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	BAR/IMD domain-like	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
Protein kinase-like (PK-like)	Dihydropteroate synthetase-like	1	1
Cysteine proteinases	WRKY DNA-binding domain	1	1
TGS-like	tRNA-intron endonuclease catalytic domain-like	1	1
F-box domain	Arp2/3 complex 21 kDa subunit ARPC3	1	1
RNA-binding domain, RBD	HCP-like	1	1
L domain-like	Ubiquitin-like	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
F-box domain	RING/U-box	1	1
L domain-like	Dihydropteroate synthetase-like	1	1
Voltage-gated potassium channels	Periplasmic binding protein-like II	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA-binding pseudobarrel domain	1	1
PapD-like	Quinoprotein alcohol dehydrogenase-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Staphylococcal nuclease	1	1
Tubby C-terminal domain-like	Tubby C-terminal domain-like	1	1
Nucleoside hydrolase	RNI-like	1	1
Arginase/deacetylase	Arginase/deacetylase	1	1
PUA domain-like	FAD/NAD(P)-binding domain	1	1
BRCT domain	ADP-ribosylation	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1
L domain-like	Outer arm dynein light chain 1	1	1
TPR-like	PH domain-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	1	1
AlbA-like	AlbA-like	1	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	1	1
Chromo domain-like	Homeodomain-like	1	1
Chaperone J-domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
GHMP Kinase, C-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	1	1
Retrovirus zinc finger-like domains	RNI-like	1	1
Surp module (SWAP domain)	Surp module (SWAP domain)	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
SAP domain	CCCH zinc finger	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
TRAF domain-like	Galactose oxidase, central domain	1	1
Nucleic acid-binding proteins	HAD-like	1	1
Cupredoxins	Clavaminate synthase-like	1	1
Translation proteins	Activating enzymes of the ubiquitin-like proteins	1	1
Ribosomal protein S10	Ribosomal protein S10	1	1
Chaperone J-domain	ARM repeat	1	1
Skp1 dimerisation domain-like	F-box domain	1	1
Terpenoid synthases	DNase I-like	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
Class II aaRS ABD-related	tRNA-intron endonuclease catalytic domain-like	1	1
PP2C-like	Nucleic acid-binding proteins	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	Ribonuclease H-like	1	1
alpha-D-mannose-specific plant lectins	Cysteine proteinases	1	1
alpha/beta-Hydrolases	Ribosomal protein S10	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
P-loop containing nucleoside triphosphate hydrolases	Rhodanese/Cell cycle control phosphatase	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
Quinoprotein alcohol dehydrogenase-like	Peptidase/esterase 'gauge' domain	1	1
Ribokinase-like	Formin homology 2 domain (FH2 domain)	1	1
TGS-like	Class II aaRS ABD-related	1	1
Concanavalin A-like lectins/glucanases	SH2 domain	1	1
FKBP-like	Triger factor/SurA peptide-binding domain-like	1	1
Terpenoid cyclases/Protein prenyltransferases	DNase I-like	1	1
HRDC-like	PLP-dependent transferases	1	1
ACT-like	Formyltransferase	1	1
Ubiquitin-like	Zn-binding ribosomal proteins	1	1
Terpenoid synthases	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
NAC domain	Carbamate kinase-like	1	1
Six-hairpin glycosidases	Ribonuclease H-like	1	1
Ribonuclease H-like	ENTH/VHS domain	1	1
DUSP-like	Ubiquitin-like	1	1
POZ domain	TPR-like	1	1
Class II aaRS and biotin synthetases	LexA/Signal peptidase	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
SET domain	FAD-linked reductases, C-terminal domain	1	1
BRCA2 helical domain	HAD-like	1	1
ARM repeat	Concanavalin A-like lectins/glucanases	1	1
BRCT domain	PsbU/PolX domain-like	1	1
Acid proteases	DNA/RNA polymerases	1	1
RNA-binding domain, RBD	PWI domain	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	1	1
Thioredoxin-like	ERP29 C domain-like	1	1
SH2 domain	SH2 domain	1	1
DNA clamp	DNA clamp	1	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	1	1
Class II aaRS and biotin synthetases	tRNA-intron endonuclease catalytic domain-like	1	1
Ribonuclease H-like	TRAF domain-like	1	1
tRNA-guanine transglycosylase	tRNA-guanine transglycosylase	1	1
Histone-fold	Histone-fold	1	1
Ubiquitin-like	Acid proteases	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
DNase I-like	HLH, helix-loop-helix DNA-binding domain	1	1
Citrate synthase	Citrate synthase	1	1
RING/U-box	Cyclophilin-like	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
FYVE/PHD zinc finger	ABC transporter transmembrane region	1	1
GroEL apical domain-like	DNA-binding domain	1	1
Chaperone J-domain	NAC domain	1	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
SMAD/FHA domain	PP2C-like	1	1
AF0104/ALDC/Ptd012-like	AF0104/ALDC/Ptd012-like	1	1
F-box domain	Rubredoxin-like	1	1
RbcX-like	RbcX-like	1	1
ARID-like	FYVE/PHD zinc finger	1	1
TPR-like	Acetamidase/Formamidase-like	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
MTH938-like	PK C-terminal domain-like	1	1
BAR/IMD domain-like	Ribonuclease H-like	1	1
Cytochrome P450	Protein kinase-like (PK-like)	1	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Acid proteases	UBA-like	1	1
Quinoprotein alcohol dehydrogenase-like	Putative isomerase YbhE	1	1
Thiolase-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
post-AAA+ oligomerization domain-like	post-AAA+ oligomerization domain-like	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
Tex N-terminal region-like	SH2 domain	1	1
Thioredoxin-like	"Winged helix" DNA-binding domain	1	1
Macro domain-like	Macro domain-like	1	1
ARM repeat	TPR-like	1	1
GYF domain	RNA-binding domain, RBD	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
F-box domain	Metallo-hydrolase/oxidoreductase	1	1
Class II aaRS ABD-related	E set domains	1	1
P-loop containing nucleoside triphosphate hydrolases	Microbial and mitochondrial ADK, insert "zinc finger" domain	1	1
RNI-like	Sigma3 and sigma4 domains of RNA polymerase sigma factors	1	1
Cytochrome b5-like heme/steroid binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
E set domains	E set domains	1	1
DNA-binding domain	DNA-binding pseudobarrel domain	1	1
DNase I-like	NAD(P)-linked oxidoreductase	1	1
DAK1/DegV-like	DhaL-like	1	1
Protein kinase-like (PK-like)	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
Chorismate mutase II	Chorismate mutase II	1	1
Type II DNA topoisomerase	Type II DNA topoisomerase	1	1
Histone-fold	Protein kinase-like (PK-like)	1	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	1	1
NAC domain	beta-beta-alpha zinc fingers	1	1
Ribosomal protein L1	Ribosomal protein L1	1	1
Protein kinase-like (PK-like)	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
UBA-like	Hect, E3 ligase catalytic domain	1	1
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	1	1
RPB5-like RNA polymerase subunit	RPB5-like RNA polymerase subunit	1	1
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
Acyl-CoA binding protein	Acyl-CoA binding protein	1	1
POZ domain	RNI-like	1	1
F-box domain	Cysteine proteinases	1	1
Ribonuclease H-like	SH2 domain	1	1
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), peptide-binding domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
Homeodomain-like	Ankyrin repeat	1	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	1	1
FMN-linked oxidoreductases	FMN-linked oxidoreductases	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
RNA-binding domain, RBD	BRCT domain	1	1
L-aspartase-like	L-aspartase-like	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
Activating enzymes of the ubiquitin-like proteins	Rhodanese/Cell cycle control phosphatase	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
Ribulose-phoshate binding barrel	Ribulose-phoshate binding barrel	1	1
Nucleic acid-binding proteins	LexA/Signal peptidase	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
Homeodomain-like	DNase I-like	1	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
F-box domain	Homeodomain-like	1	1
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	1	1
YgbK-like	Aldolase	1	1
VPS9 domain	VPS9 domain	1	1
RuBisCO, small subunit	RuBisCO, small subunit	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
TRAF domain-like	Multiheme cytochromes	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
Ribonuclease H-like	beta-sandwich domain of Sec23/24	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	Quinoprotein alcohol dehydrogenase-like	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	1	1
DNA-binding pseudobarrel domain	TRAF domain-like	1	1
Helical domain of Sec23/24	Helical domain of Sec23/24	1	1
Protein kinase-like (PK-like)	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
Bromodomain	DNA-binding pseudobarrel domain	1	1
L domain-like	Rhodanese/Cell cycle control phosphatase	1	1
(Trans)glycosidases	Homeodomain-like	1	1
ArfGap/RecO-like zinc finger	Ribonuclease H-like	1	1
PHP domain-like	PHP domain-like	1	1
Cysteine proteinases	DUSP-like	1	1
t-snare proteins	Translation proteins	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Homeodomain-like	POZ domain	1	1
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
L domain-like	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	1	1
RNI-like	Arginase/deacetylase	1	1
FYVE/PHD zinc finger	Mitochondrial carrier	1	1
Cytochrome P450	RNI-like	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	1	1
Cytidine deaminase-like	Concanavalin A-like lectins/glucanases	1	1
Ribonuclease H-like	Acid proteases	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
Chaperone J-domain	RNA-binding domain, RBD	1	1
Taf5 N-terminal domain-like	L domain-like	1	1
TK C-terminal domain-like	BAR/IMD domain-like	1	1
PFL-like glycyl radical enzymes	ARM repeat	1	1
Clavaminate synthase-like	Staphylococcal nuclease	1	1
Thioredoxin-like	FAD-dependent thiol oxidase	1	1
(Trans)glycosidases	Ribokinase-like	1	1
Chaperone J-domain	Homeodomain-like	1	1
Mitochondrial glycoprotein MAM33-like	Mitochondrial glycoprotein MAM33-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Peptidase/esterase 'gauge' domain	Peptidase/esterase 'gauge' domain	1	1
Acyl-CoA binding protein	Kelch motif	1	1
EF-hand	Calponin-homology domain, CH-domain	1	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PUA domain-like	FAD-linked reductases, C-terminal domain	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Galactose-binding domain-like	FAD-linked reductases, C-terminal domain	1	1
Hypothetical protein YjiA, C-terminal domain	Quinoprotein alcohol dehydrogenase-like	1	1
SWIB/MDM2 domain	eIF1-like	1	1
YaeB-like	YaeB-like	1	1
HIT-like	HIT-like	1	1
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Class II aaRS and biotin synthetases	E set domains	1	1
P-loop containing nucleoside triphosphate hydrolases	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	1	1
DNA/RNA polymerases	vWA-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	DNA/RNA polymerases	1	1
ARM repeat	PH domain-like	1	1
TPR-like	RNA-binding domain, RBD	1	1
WD40 repeat-like	Cyclophilin-like	1	1
ssDNA-binding transcriptional regulator domain	ssDNA-binding transcriptional regulator domain	1	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	1	1
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	1	1
Sm-like ribonucleoproteins	BolA-like	1	1
RNI-like	Metallo-hydrolase/oxidoreductase	1	1
Cytochrome P450	Cyclin-like	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
CAD & PB1 domains	RING/U-box	1	1
(Phosphotyrosine protein) phosphatases II	Macro domain-like	1	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	1	1
Aconitase iron-sulfur domain	Aconitase iron-sulfur domain	1	1
FAD-linked reductases, C-terminal domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
ADP-ribosylation	Hemopexin-like domain	1	1
R3H domain	Ribosomal protein L1	1	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
L domain-like	Formin homology 2 domain (FH2 domain)	1	1
SET domain	FAD/NAD(P)-binding domain	1	1
SGNH hydrolase	SGNH hydrolase	1	1
BRCT domain	Ubiquitin-like	1	1
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
CheY-like	CheY-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
Heme oxygenase-like	Heme oxygenase-like	1	1
UraD-Like	Transthyretin (synonym: prealbumin)	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
Ribonuclease H-like	ABC transporter transmembrane region	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Concanavalin A-like lectins/glucanases	Cysteine proteinases	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
Histone-fold	RNA-binding domain, RBD	1	1
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	1	1
SET domain	SET domain	1	1
L domain-like	Ankyrin repeat	1	1
Tim10-like	(Trans)glycosidases	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Formin homology 2 domain (FH2 domain)	F-box domain	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	DNA-binding pseudobarrel domain	1	1
Calcium ATPase, transmembrane domain M	Calcium ATPase, transmembrane domain M	1	1
ThrRS/AlaRS common domain	E set domains	1	1
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	1	1
UBA-like	PUG domain-like	1	1
Arginase/deacetylase	NAD(P)-binding Rossmann-fold domains	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1
Nucleotide-binding domain	alpha/beta-Hydrolases	1	1
Protein kinase-like (PK-like)	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
POZ domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Cytochrome P450	F-box domain	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
Concanavalin A-like lectins/glucanases	EGF/Laminin	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
YjbQ-like	PLC-like phosphodiesterases	1	1
UBC-like	UBA-like	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
Eukaryotic type KH-domain (KH-domain type I)	beta-Roll	1	1
Outer arm dynein light chain 1	RNI-like	1	1
Ran binding protein zinc finger-like	RNA-binding domain, RBD	1	1
Protein kinase-like (PK-like)	Calponin-homology domain, CH-domain	1	1
F-box domain	Sigma3 and sigma4 domains of RNA polymerase sigma factors	1	1
Urease, gamma-subunit	Metallo-dependent hydrolases	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
DNase I-like	LeuD/IlvD-like	1	1
Arabinanase/levansucrase/invertase	Homeodomain-like	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
FMN-binding split barrel	FMN-binding split barrel	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Protein kinase-like (PK-like)	1	1
SAICAR synthase-like	SAICAR synthase-like	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	1	1
Formin homology 2 domain (FH2 domain)	Zn-dependent exopeptidases	1	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	1	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	1	1
Nucleic acid-binding proteins	UBA-like	1	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	1	1
PR-1-like	PR-1-like	1	1
Thiolase-like	Cysteine proteinases	1	1
D-aminoacid aminotransferase-like PLP-dependent enzymes	D-aminoacid aminotransferase-like PLP-dependent enzymes	1	1
TRAF domain-like	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Cytochrome P450	alpha/beta-Hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Epsilon subunit of F1F0-ATP synthase N-terminal domain	1	1
TGS-like	ACT-like	1	1
LysM domain	LysM domain	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
Ubiquitin-like	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
Argininosuccinate synthetase, C-terminal domain	Argininosuccinate synthetase, C-terminal domain	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
ARM repeat	Carbamate kinase-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	1	1
TPR-like	Metallo-dependent phosphatases	1	1
Ribosomal protein S5 domain 2-like	(Phosphotyrosine protein) phosphatases II	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
Tropomyosin	Mitotic arrest deficient-like 1, Mad1	1	1
Retrovirus zinc finger-like domains	Ribonuclease H-like	1	1
Nucleoporin domain	Homeodomain-like	1	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	1	1
NTF2-like	L domain-like	1	1
GroEL apical domain-like	GroEL apical domain-like	1	1
F-box domain	DNase I-like	1	1
Nucleic acid-binding proteins	DNA/RNA polymerases	1	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
L domain-like	alpha/beta knot	1	1
Chromo domain-like	L domain-like	1	1
Nucleotidyltransferase	ACT-like	1	1
Nucleoporin domain	WD40 repeat-like	1	1
Ubiquitin-like	Bromodomain	1	1
MTH938-like	PK beta-barrel domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
DNA repair protein MutS, domain I	GIY-YIG endonuclease	1	1
GYF domain	F-box domain	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	HSP20-like chaperones	1	1
PUA domain-like	Ran binding protein zinc finger-like	1	1
Pseudouridine synthase	RNI-like	1	1
ThrRS/AlaRS common domain	tRNA-intron endonuclease catalytic domain-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
RNI-like	WD40 repeat-like	1	1
Protein kinase-like (PK-like)	ENTH/VHS domain	1	1
Thiolase-like	ARM repeat	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
WD40 repeat-like	NHL repeat	1	1
Enolase N-terminal domain-like	Enolase N-terminal domain-like	1	1
GST C-terminal domain-like	eEF-1beta-like	1	1
Lysozyme-like	Heme-dependent peroxidases	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
GST C-terminal domain-like	Nucleic acid-binding proteins	1	1
TPR-like	EF-hand	1	1
DNA/RNA polymerases	Nucleotide-diphospho-sugar transferases	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
Periplasmic binding protein-like I	Periplasmic binding protein-like I	1	1
F-box domain	DNA/RNA polymerases	1	1
RNA-binding domain, RBD	Protein kinase-like (PK-like)	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	1	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	1	1
BRCT domain	Nucleotidyltransferase	1	1
Chaperone J-domain	Macro domain-like	1	1
Homeodomain-like	Phosphoenolpyruvate/pyruvate domain	1	1
Lipocalins	Lipocalins	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Ribosomal protein S5 domain 2-like	L domain-like	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
Protein kinase-like (PK-like)	NAD(P)-binding Rossmann-fold domains	1	1
FAD/NAD-linked reductases, dimerisation (C-terminal) domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
UBC-like	P-loop containing nucleoside triphosphate hydrolases	1	1
LysM domain	WD40 repeat-like	1	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
At5g01610-like	At5g01610-like	1	1
RNI-like	NAD(P)-binding Rossmann-fold domains	1	1
FKBP-like	Ribonuclease H-like	1	1
GHMP Kinase, C-terminal domain	E set domains	1	1
GAF domain-like	CAD & PB1 domains	1	1
RNI-like	Clavaminate synthase-like	1	1
L domain-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
DNA/RNA polymerases	C-terminal, gelsolin-like domain of Sec23/24	1	1
TPR-like	RNI-like	1	1
Mannose-binding lectins	PapD-like	1	1
RNI-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
YbaK/ProRS associated domain	YbaK/ProRS associated domain	1	1
DNA/RNA polymerases	Peptidase/esterase 'gauge' domain	1	1
VPS28 C-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
DNA-binding pseudobarrel domain	DNase I-like	1	1
Nucleic acid-binding proteins	RNI-like	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Thioredoxin-like	HIT-like	1	1
ARM repeat	Pectin lyase-like	1	1
SET domain	Cyclin-like	1	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
Osmotin, thaumatin-like protein	RING/U-box	1	1
POZ domain	SET domain	1	1
PUA domain-like	alpha/beta knot	1	1
Adenine nucleotide alpha hydrolases-like	Ribonuclease H-like	1	1
Chromo domain-like	ABC transporter transmembrane region	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
Aquaporin-like	F-box domain	1	1
SufE/NifU	HesB-like domain	1	1
beta-sandwich domain of Sec23/24	beta-sandwich domain of Sec23/24	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
vWA-like	C-terminal domain of Ku80	1	1
Protein kinase-like (PK-like)	DNA-binding domain	1	1
LEA14-like	Formin homology 2 domain (FH2 domain)	1	1
Ubiquitin-like	PUG domain-like	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
GAD domain-like	LexA/Signal peptidase	1	1
Chromo domain-like	Protein kinase-like (PK-like)	1	1
Cryptochrome/photolyase FAD-binding domain	Cryptochrome/photolyase FAD-binding domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
Nucleotidylyl transferase	Ran binding protein zinc finger-like	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	1	1
(Trans)glycosidases	L domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein L16p/L10e	1	1
dsRNA-binding domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
RNA-binding domain, RBD	alpha-D-mannose-specific plant lectins	1	1
Beta-D-glucan exohydrolase, C-terminal domain	Beta-D-glucan exohydrolase, C-terminal domain	1	1
HAD-like	Riboflavin kinase-like	1	1
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	1	1
Ribonuclease H-like	Formin homology 2 domain (FH2 domain)	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Ankyrin repeat	"Winged helix" DNA-binding domain	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
RmlC-like cupins	NAC domain	1	1
Cysteine proteinases	PapD-like	1	1
PDZ domain-like	ClpP/crotonase	1	1
DNA/RNA polymerases	DNA/RNA polymerases	1	1
POZ domain	GYF domain	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Concanavalin A-like lectins/glucanases	DNA/RNA polymerases	1	1
HIT-like	RING/U-box	1	1
L domain-like	Concanavalin A-like lectins/glucanases	1	1
(Trans)glycosidases	DNA/RNA polymerases	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	1	1
Ribonuclease H-like	Helical domain of Sec23/24	1	1
TPR-like	Peptide methionine sulfoxide reductase	1	1
HSP20-like chaperones	Phospholipase C/P1 nuclease	1	1
PH domain-like	Ribonuclease H-like	1	1
Homeodomain-like	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
PH domain-like	Phospholipase D/nuclease	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Cytochrome P450	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	F-box domain	1	1
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
ADP-ribosylation	Acid proteases	1	1
Class II aaRS and biotin synthetases	ARM repeat	1	1
Formin homology 2 domain (FH2 domain)	SET domain	1	1
ARM repeat	PLP-dependent transferases	1	1
F-box domain	L9 N-domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	1	1
F-box domain	Acetyl-CoA synthetase-like	1	1
DNA/RNA polymerases	Quinoprotein alcohol dehydrogenase-like	1	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Protein kinase-like (PK-like)	1	1
Thioredoxin-like	Macro domain-like	1	1
Cytidine deaminase-like	Dihydrofolate reductase-like	1	1
TRAF domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
ARM repeat	alpha/beta knot	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
ARM repeat	"Winged helix" DNA-binding domain	1	1
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	1	1
DPP6 N-terminal domain-like	Quinoprotein alcohol dehydrogenase-like	1	1
HCP-like	Riboflavin synthase domain-like	1	1
ADP-ribosylation	Ribosomal protein S10	1	1
Carbohydrate phosphatase	Carbohydrate phosphatase	1	1
F-box domain	PUA domain-like	1	1
Metallo-hydrolase/oxidoreductase	ARM repeat	1	1
SMAD/FHA domain	Phospholipase D/nuclease	1	1
Metalloproteases ("zincins"), catalytic domain	HAD-like	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	TRAF domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Protein kinase-like (PK-like)	1	1
L domain-like	ARM repeat	1	1
Kelch motif	Subtilisin-like	1	1
TPR-like	HIT/MYND zinc finger-like	1	1
Tubulin C-terminal domain-like	Tubulin C-terminal domain-like	1	1
Protein kinase-like (PK-like)	Pseudouridine synthase	1	1
Protein kinase-like (PK-like)	dUTPase-like	1	1
TGS-like	EF-hand	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	Cysteine proteinases	1	1
Flavoproteins	Radical SAM enzymes	1	1
SAP domain	DNase I-like	1	1
GroES-like	L domain-like	1	1
Chaperone J-domain	CSL zinc finger	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
Actin-like ATPase domain	AF1104-like	1	1
PLP-dependent transferases	Carbamate kinase-like	1	1
Dcp2 domain-like	Nudix	1	1
SNARE fusion complex	Translation proteins	1	1
Lesion bypass DNA polymerase (Y-family), little finger domain	HAD-like	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
TRAF domain-like	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	S-adenosyl-L-methionine-dependent methyltransferases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Mitochondrial carrier	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Protein prenylyltransferase	Outer arm dynein light chain 1	1	1
Peptide methionine sulfoxide reductase	Peptide methionine sulfoxide reductase	1	1
Dihydrofolate reductase-like	Concanavalin A-like lectins/glucanases	1	1
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Phospholipase D/nuclease	Concanavalin A-like lectins/glucanases	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
DNA/RNA polymerases	Helical domain of Sec23/24	1	1
P-loop containing nucleoside triphosphate hydrolases	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Scorpion toxin-like	F-box domain	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RNA-binding domain, RBD	1	1
TPR-like	Cysteine proteinases	1	1
CAD & PB1 domains	CAD & PB1 domains	1	1
Cyclin-like	Trypsin-like serine proteases	1	1
Tudor/PWWP/MBT	L domain-like	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	N-terminal domain of alpha and beta subunits of F1 ATP synthase	1	1
DNase I-like	Aconitase iron-sulfur domain	1	1
Protein kinase-like (PK-like)	Peptide methionine sulfoxide reductase	1	1
DTD-like	DTD-like	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
Cysteine proteinases	Homeodomain-like	1	1
GYF domain	Formin homology 2 domain (FH2 domain)	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
L domain-like	Clavaminate synthase-like	1	1
Chaperone J-domain	E set domains	1	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	1	1
PapD-like	Peptidase/esterase 'gauge' domain	1	1
DAK1/DegV-like	DAK1/DegV-like	1	1
L domain-like	Tryptophan synthase beta subunit-like PLP-dependent enzymes	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
DNase I-like	Translation proteins	1	1
Actin-crosslinking proteins	Actin-crosslinking proteins	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
ARM repeat	Clavaminate synthase-like	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Nucleotidylyl transferase	Protein kinase-like (PK-like)	1	1
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
HLH, helix-loop-helix DNA-binding domain	LeuD/IlvD-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	L domain-like	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Protein kinase-like (PK-like)	Arginase/deacetylase	1	1
GroEL equatorial domain-like	DNA-binding domain	1	1
(Trans)glycosidases	Phospholipase D/nuclease	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Clathrin adaptor appendage domain	Clathrin adaptor appendage domain	1	1
Rhomboid-like	Rhomboid-like	1	1
Subtilisin-like	Chaperone J-domain	1	1
DNase I-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	1	1
R3H domain	Ankyrin repeat	1	1
SSo0622-like	Kelch motif	1	1
PUA domain-like	RING/U-box	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
Thiamin pyrophosphokinase, substrate-binding domain	Glycerol-3-phosphate (1)-acyltransferase	1	1
Thioredoxin-like	Kelch motif	1	1
(Trans)glycosidases	FAD-linked reductases, C-terminal domain	1	1
Periplasmic binding protein-like I	Voltage-gated potassium channels	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
Histone-fold	ARM repeat	1	1
HMG-box	HMG-box	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
RCC1/BLIP-II	F-box domain	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	1	1
Urease, beta-subunit	Metallo-dependent hydrolases	1	1
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	1	1
HD-domain/PDEase-like	ACT-like	1	1
Ribonuclease H-like	Ubiquitin-like	1	1
GHMP Kinase, C-terminal domain	DNA/RNA polymerases	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
POZ domain	PLC-like phosphodiesterases	1	1
Galactose-binding domain-like	FAD/NAD(P)-binding domain	1	1
NAD kinase/diacylglycerol kinase-like	NAD kinase/diacylglycerol kinase-like	1	1
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	1	1
TPR-like	HSP20-like chaperones	1	1
TrmE connector domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
Galactose mutarotase-like	Galactose mutarotase-like	1	1
Ribokinase-like	AMMECR1-like	1	1
(Trans)glycosidases	UBC-like	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
Dihydrofolate reductase-like	YbiA-like	1	1
Phosphoenolpyruvate/pyruvate domain	Phosphoenolpyruvate/pyruvate domain	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	1	1
SufE/NifU	BolA-like	1	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	1	1
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	TPR-like	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	1	1
ABC transporter transmembrane region	LuxS/MPP-like metallohydrolase	1	1
Leucine zipper domain	Ubiquitin-like	1	1
Class I glutamine amidotransferase-like	ADC synthase	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
Preprotein translocase SecY subunit	Preprotein translocase SecY subunit	1	1
alpha/beta-Hydrolases	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	1	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
Nucleotidyltransferase	TGS-like	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	N-terminal domain of adenylylcyclase associated protein, CAP	1	1
DNase I-like	Translation proteins SH3-like domain	1	1
L domain-like	Glutamyl tRNA-reductase dimerization domain	1	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	1	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	1	1
Vacuolar ATP synthase subunit C	Vacuolar ATP synthase subunit C	1	1
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	ARM repeat	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Homeodomain-like	1	1
PYP-like sensor domain (PAS domain)	Kelch motif	1	1
GroES-like	F-box domain	1	1
FAD/NAD(P)-binding domain	alpha/beta-Hydrolases	1	1
Retrovirus zinc finger-like domains	Subtilisin-like	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Skp1 dimerisation domain-like	Skp1 dimerisation domain-like	1	1
Retrovirus zinc finger-like domains	P-loop containing nucleoside triphosphate hydrolases	1	1
POZ domain	Protein kinase-like (PK-like)	1	1
ARM repeat	SH3-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Protein kinase-like (PK-like)	1	1
Chaperone J-domain	HIT-like	1	1
Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	1	1
Cyclophilin-like	Retrovirus zinc finger-like domains	1	1
HCP-like	Homing endonucleases	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Radical SAM enzymes	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
MCP/YpsA-like	MCP/YpsA-like	1	1
Cytochrome P450	PP2C-like	1	1
Peptidyl-tRNA hydrolase II	RNA-binding domain, RBD	1	1