All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
| Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
|---|
| GroES-like | NAD(P)-binding Rossmann-fold domains | 27 | 5 |  |
| Thioredoxin-like | GST C-terminal domain-like | 21 | 3 | |
| RNA-binding domain, RBD | RNA-binding domain, RBD | 19 | 8 | |
| Thiolase-like | Thiolase-like | 12 | 2 | |
| Thioredoxin-like | Thioredoxin-like | 10 | 7 | |
| Plant lectins/antimicrobial peptides | Lysozyme-like | 8 | 2 | |
| GroES-like | GroES-like | 8 | 3 | |
| "Winged helix" DNA-binding domain | S-adenosyl-L-methionine-dependent methyltransferases | 8 | 1 | |
| NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 7 | 4 | |
| SNARE-like | SNARE fusion complex | 7 | 1 | |
| Actin-like ATPase domain | Actin-like ATPase domain | 6 | 4 | |
| F-box domain | RNI-like | 6 | 3 | |
| NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 6 | 1 | |
| Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 5 | 2 | |
| Terpenoid cyclases/Protein prenyltransferases | Terpenoid synthases | 5 | 2 | |
| (Trans)glycosidases | Glycosyl hydrolase domain | 5 | 1 | |
| CRAL/TRIO N-terminal domain | CRAL/TRIO domain | 5 | 2 | |
| NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 5 | 2 | |
| Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 4 | 1 | |
| RNA-binding domain, RBD | Retrovirus zinc finger-like domains | 4 | 2 | |
| Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 4 | 3 | |
| P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 4 | 1 | |
| FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 4 | 2 | |
| P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 4 | 1 | |
| Barwin-like endoglucanases | PHL pollen allergen | 4 | 1 | |
| Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 4 | 3 | |
| F-box domain | Kelch motif | 4 | 2 | |
| GroEL equatorial domain-like | GroEL apical domain-like | 3 | 3 | |
| Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 3 | 1 | |
| Glucocorticoid receptor-like (DNA-binding domain) | AN1-like Zinc finger | 3 | 1 | |
| Cysteine-rich domain | Cysteine-rich domain | 3 | 1 | |
| Nucleic acid-binding proteins | Nucleic acid-binding proteins | 3 | 3 | |
| Plant invertase/pectin methylesterase inhibitor | Pectin lyase-like | 3 | 1 | |
| Cystatin/monellin | Cystatin/monellin | 3 | 1 | |
| Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 3 | 3 | |
| S-adenosyl-L-methionine-dependent methyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 3 | 2 | |
| Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 3 | 3 | |
| GroEL equatorial domain-like | GroEL-intermediate domain like | 3 | 3 | |
| Glucocorticoid receptor-like (DNA-binding domain) | Glucocorticoid receptor-like (DNA-binding domain) | 3 | 1 | |
| GroEL-intermediate domain like | GroEL apical domain-like | 3 | 3 | |
| Chaperone J-domain | 4Fe-4S ferredoxins | 3 | 2 | |
| Fe-S cluster assembly (FSCA) domain-like | Fe-S cluster assembly (FSCA) domain-like | 2 | 1 | |
| Cupredoxins | Cupredoxins | 2 | 2 | |
| vWA-like | RING/U-box | 2 | 1 | |
| P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 | |
| Eukaryotic type KH-domain (KH-domain type I) | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 | |
| CCCH zinc finger | Eukaryotic type KH-domain (KH-domain type I) | 2 | 2 | |
| PA domain | RING/U-box | 2 | 2 | |
| Ubiquitin-like | UBA-like | 2 | 2 | |
| Retrovirus zinc finger-like domains | Retrovirus zinc finger-like domains | 2 | 2 | |
| POZ domain | Skp1 dimerisation domain-like | 2 | 1 | |
| Ricin B-like lectins | Ricin B-like lectins | 2 | 1 | |
| Arabinanase/levansucrase/invertase | Arabinanase/levansucrase/invertase | 2 | 1 | |
| Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 2 | 1 | |
| Ran binding protein zinc finger-like | Ran binding protein zinc finger-like | 2 | 2 | |
| P-loop containing nucleoside triphosphate hydrolases | Hypothetical protein YjiA, C-terminal domain | 2 | 1 | |
| HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 2 | 2 | |
| Concanavalin A-like lectins/glucanases | P-domain of calnexin/calreticulin | 2 | 1 | |
| Thioesterase/thiol ester dehydrase-isomerase | Thioesterase/thiol ester dehydrase-isomerase | 2 | 2 | |
| Translation initiation factor 2 beta, aIF2beta, N-terminal domain | Zinc-binding domain of translation initiation factor 2 beta | 2 | 1 | |
| Cytochrome c | Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor | 2 | 1 | |
| F1F0 ATP synthase subunit C | F1F0 ATP synthase subunit C | 2 | 1 | |
| ENTH/VHS domain | GAT-like domain | 2 | 2 | |
| CCCH zinc finger | CCCH zinc finger | 2 | 2 | |
| Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 2 | 2 | |
| DEK C-terminal domain | SWIB/MDM2 domain | 2 | 1 | |
| Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 2 | 2 | |
| Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 2 | 2 | |
| Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 2 | 2 | |
| FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 2 | 2 | |
| dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 2 | 1 | |
| ACT-like | ACT-like | 2 | 2 | |
| Ribosomal protein L6 | Ribosomal protein L6 | 2 | 2 | |
| SWIB/MDM2 domain | SWIB/MDM2 domain | 2 | 1 | |
| FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 2 | 2 | |
| Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 2 | 2 | |
| Translation proteins SH3-like domain | Nucleic acid-binding proteins | 2 | 2 | |
| Thioredoxin-like | Cysteine-rich domain | 2 | 2 | |
| Transcription factor IIA (TFIIA), alpha-helical domain | Transcription factor IIA (TFIIA), beta-barrel domain | 2 | 2 | |
| FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 1 | 1 | |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Zinc beta-ribbon | 1 | 1 | |
| FKBP-like | FKBP-like | 1 | 1 | |
| Chaperone J-domain | RNA-binding domain, RBD | 1 | 1 | |
| Nucleic acid-binding proteins | eIF-2-alpha, C-terminal domain | 1 | 1 | |
| FAS1 domain | FAS1 domain | 1 | 1 | |
| Cysteine proteinases | Granulin repeat | 1 | 1 | |
| dsRNA-binding domain-like | dsRNA-binding domain-like | 1 | 1 | |
| WWE domain | RING/U-box | 1 | 1 | |
| ARM repeat | ARM repeat | 1 | 1 | |
| Cyclin-like | Cyclin-like | 1 | 1 | |
| (Trans)glycosidases | Galactose-binding domain-like | 1 | 1 | |
| cAMP-binding domain-like | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 | |
| YjeF N-terminal domain-like | FMN-binding split barrel | 1 | 1 | |
| HSP20-like chaperones | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
| Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 1 | 1 | |
| Toll/Interleukin receptor TIR domain | Mannose-binding lectins | 1 | 1 | |
| 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain | Alkaline phosphatase-like | 1 | 1 | |
| F-box domain | WD40 repeat-like | 1 | 1 | |
| Macro domain-like | Zn-dependent exopeptidases | 1 | 1 | |
| Ran binding protein zinc finger-like | RING/U-box | 1 | 1 | |
| Periplasmic binding protein-like II | ACT-like | 1 | 1 | |
| Ubiquitin-like | XPC-binding domain | 1 | 1 | |
| P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 1 | 1 | |
| Formate/glycerate dehydrogenase catalytic domain-like | Serine metabolism enzymes domain | 1 | 1 | |
| GST C-terminal domain-like | eEF1-gamma domain | 1 | 1 | |
| Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 1 | 1 | |
| Class I glutamine amidotransferase-like | Class I glutamine amidotransferase-like | 1 | 1 | |
| Ubiquitin-like | PUG domain-like | 1 | 1 | |
| NAD(P)-binding Rossmann-fold domains | ACT-like | 1 | 1 | |
| Hypothetical protein SAV1430 | Fe-S cluster assembly (FSCA) domain-like | 1 | 1 | |
| Ubiquitin-like | BAG domain | 1 | 1 | |
| Hypothetical protein AF0491, middle domain | beta-beta-alpha zinc fingers | 1 | 1 | |
| P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 1 | 1 | |
| Creatinase/aminopeptidase | "Winged helix" DNA-binding domain | 1 | 1 | |
| Carbamate kinase-like | ACT-like | 1 | 1 | |
| FMN-linked oxidoreductases | FMN-linked oxidoreductases | 1 | 1 | |
| HD-domain/PDEase-like | EF-hand | 1 | 1 | |
| SET domain | RuBisCo LSMT C-terminal, substrate-binding domain | 1 | 1 | |
| Metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
| Serine metabolism enzymes domain | ACT-like | 1 | 1 | |
| Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 | |
| Acyl-CoA binding protein | Ankyrin repeat | 1 | 1 | |
| LysM domain | LysM domain | 1 | 1 | |
| Eukaryotic type KH-domain (KH-domain type I) | Chaperone J-domain | 1 | 1 | |
| ClpP/crotonase | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 | |
| NagB/RpiA/CoA transferase-like | D-ribose-5-phosphate isomerase (RpiA), lid domain | 1 | 1 | |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Elongation factor TFIIS domain 2 | 1 | 1 | |
| 4Fe-4S ferredoxins | Metallo-hydrolase/oxidoreductase | 1 | 1 | |
| L9 N-domain-like | Ribosomal protein L9 C-domain | 1 | 1 | |
| PK beta-barrel domain-like | PK C-terminal domain-like | 1 | 1 | |
| Protein kinase-like (PK-like) | RING/U-box | 1 | 1 | |
| AN1-like Zinc finger | AN1-like Zinc finger | 1 | 1 | |
| Protein kinase-like (PK-like) | EF-hand | 1 | 1 | |
| Elongation factor TFIIS domain 2 | Zinc beta-ribbon | 1 | 1 | |
| Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 | |
| Dcp2 domain-like | Nudix | 1 | 1 | |
| Nucleotidyltransferase | EF-hand | 1 | 1 | |
| Ankyrin repeat | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
| beta-beta-alpha zinc fingers | beta-beta-alpha zinc fingers | 1 | 1 | |
| Formate/glycerate dehydrogenase catalytic domain-like | Formate/glycerate dehydrogenase catalytic domain-like | 1 | 1 | |
| Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 1 | 1 | |
| lambda repressor-like DNA-binding domains | Cyanase C-terminal domain | 1 | 1 | |
| (Trans)glycosidases | Beta-D-glucan exohydrolase, C-terminal domain | 1 | 1 | |
| WWE domain | WWE domain | 1 | 1 | |
| NTF2-like | Probable bacterial effector-binding domain | 1 | 1 | |
| MIT domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
| Rhodanese/Cell cycle control phosphatase | Rhodanese/Cell cycle control phosphatase | 1 | 1 | |
| Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 | |
| Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 1 | 1 | |
| TPR-like | TPR-like | 1 | 1 | |
| Galactose-binding domain-like | Galactose-binding domain-like | 1 | 1 | |
| Terpenoid cyclases/Protein prenyltransferases | Terpenoid cyclases/Protein prenyltransferases | 1 | 1 | |
| ClpP/crotonase | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
| Ubiquitin-like | Cysteine proteinases | 1 | 1 | |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | FabD/lysophospholipase-like | 1 | 1 | |
| Aldolase | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
| FKBP-like | TPR-like | 1 | 1 | |
| RNA-binding domain, RBD | DPP6 N-terminal domain-like | 1 | 1 | |
| Alpha-L RNA-binding motif | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
| P-loop containing nucleoside triphosphate hydrolases | TGS-like | 1 | 1 | |
| DNA clamp | DNA clamp | 1 | 1 | |
| FYSH domain | Hypothetical protein AF0491, middle domain | 1 | 1 | |
| RNase III domain-like | RNase III domain-like | 1 | 1 | |
| HAD-like | NTF2-like | 1 | 1 | |
| NAD(P)-linked oxidoreductase | CBS-domain pair | 1 | 1 | |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 | |
| UDP-Glycosyltransferase/glycogen phosphorylase | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 | |
| Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
| FYSH domain | beta-beta-alpha zinc fingers | 1 | 1 | |
| N-utilization substance G protein NusG, N-terminal domain | Translation proteins SH3-like domain | 1 | 1 | |
| UBC-like | UBA-like | 1 | 1 | |
| Calponin-homology domain, CH-domain | EB1 dimerisation domain-like | 1 | 1 | |
| HMA, heavy metal-associated domain | Cu,Zn superoxide dismutase-like | 1 | 1 | |
| Glutamine synthetase, N-terminal domain | Glutamine synthetase/guanido kinase | 1 | 1 | |
| Trypsin-like serine proteases | PDZ domain-like | 1 | 1 | |
| Phospholipase D/nuclease | Phospholipase D/nuclease | 1 | 1 | |
| Adenine nucleotide alpha hydrolases-like | Thioredoxin-like | 1 | 1 | |
| Thioredoxin-like | TPR-like | 1 | 1 | |
| P-loop containing nucleoside triphosphate hydrolases | Microbial and mitochondrial ADK, insert "zinc finger" domain | 1 | 1 | |
| F-box domain | Cullin repeat-like | 1 | 1 | |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
| ARID-like | HMG-box | 1 | 1 | |
| HisI-like | all-alpha NTP pyrophosphatases | 1 | 1 | |
| NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
| GST C-terminal domain-like | eEF-1beta-like | 1 | 1 | |
| ISP domain | Bet v1-like | 1 | 1 | |
| Translation proteins | Translation proteins | 1 | 1 | |
| UBA-like | UBA-like | 1 | 1 | |
| PX domain | BAR/IMD domain-like | 1 | 1 | |
| "Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 1 | 1 | |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 1 | 1 | |
| EF-hand | Mitochondrial carrier | 1 | 1 | |
| (Phosphotyrosine protein) phosphatases II | E set domains | 1 | 1 | |
| PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
| Acid proteases | Saposin | 1 | 1 | |
| Protein kinase-like (PK-like) | L domain-like | 1 | 1 | |
| Macro domain-like | CRAL/TRIO domain | 1 | 1 | |
| Formate/glycerate dehydrogenase catalytic domain-like | ACT-like | 1 | 1 | |
| POZ domain | Tricorn protease domain 2 | 1 | 1 | |
| eIF2alpha middle domain-like | eIF-2-alpha, C-terminal domain | 1 | 1 | |
| Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 1 | 1 | |
| Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 1 | 1 | |
| Saposin | Saposin | 1 | 1 | |
| NAD(P)-binding Rossmann-fold domains | Serine metabolism enzymes domain | 1 | 1 | |
| PDZ domain-like | Rubredoxin-like | 1 | 1 | |
| Purple acid phosphatase, N-terminal domain | Metallo-dependent phosphatases | 1 | 1 | |
| DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
| PUA domain-like | PUA domain-like | 1 | 1 | |
| ARM repeat | "Winged helix" DNA-binding domain | 1 | 1 | |
| PDZ domain-like | ClpP/crotonase | 1 | 1 | |
| RNase III domain-like | dsRNA-binding domain-like | 1 | 1 | |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 1 | 1 | |
| Aldolase | Aminoacid dehydrogenase-like, N-terminal domain | 1 | 1 | |
| Translation proteins | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |
| ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
| Ubiquitin-like | Ubiquitin-like | 1 | 1 | |
| Ypt/Rab-GAP domain of gyp1p | Ypt/Rab-GAP domain of gyp1p | 1 | 1 | |
| Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 1 | 1 | |
| t-snare proteins | SNARE fusion complex | 1 | 1 | |
| RING/U-box | ARM repeat | 1 | 1 | |
| RING/U-box | TRAF domain-like | 1 | 1 | |
| Activator of Hsp90 ATPase, Aha1 | Bet v1-like | 1 | 1 | |
| Ankyrin repeat | Protein kinase-like (PK-like) | 1 | 1 | |
| HD-domain/PDEase-like | Nucleotidyltransferase | 1 | 1 | |
| Eukaryotic RPB5 N-terminal domain | RPB5-like RNA polymerase subunit | 1 | 1 | |
| Thioredoxin-like | ERP29 C domain-like | 1 | 1 | |
| RING/U-box | RING/U-box | 1 | 1 | |
| RING/U-box | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
| MOSC N-terminal domain-like | PK beta-barrel domain-like | 1 | 1 | |
| Acyl-CoA dehydrogenase C-terminal domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 1 | 1 | |
| UBA-like | XPC-binding domain | 1 | 1 | |
| Adenine nucleotide alpha hydrolases-like | Argininosuccinate synthetase, C-terminal domain | 1 | 1 | |
| HSP20-like chaperones | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | 1 | |
| TRAF domain-like | POZ domain | 1 | 1 | |
| NusB-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
| Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 1 | 1 | |
| HAD-like | Glycerol-3-phosphate (1)-acyltransferase | 1 | 1 | |
| Thioredoxin-like | eEF1-gamma domain | 1 | 1 | |
| Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
| Nucleic acid-binding proteins | eIF2alpha middle domain-like | 1 | 1 | |
| Aconitase iron-sulfur domain | LeuD/IlvD-like | 1 | 1 | |
| Cytidine deaminase-like | Cytidine deaminase-like | 1 | 1 | |
| Ankyrin repeat | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
| DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 1 | 1 | |
| PUA domain-like | alpha/beta knot | 1 | 1 | |
| Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 1 | 1 | |
| Proton glutamate symport protein | SpoIIaa-like | 1 | 1 | |
| PriA/YqbF domain | GINS helical bundle-like | 1 | 1 | |
| Concanavalin A-like lectins/glucanases | Protein kinase-like (PK-like) | 1 | 1 | |
| P-loop containing nucleoside triphosphate hydrolases | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
| Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 1 | 1 | |
| Rhomboid-like | UBA-like | 1 | 1 | |
