Domain combination pairs in Amborella trichopoda 22

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

• For a list of unique full length architectures for this genome click here (can be slow).

Graph of adjacent domain pairs.

• Remove domain pairs for which there is already a structure in the PDB
• Remove domain pairs which occur in any other genomes (slow)
• Remove domain pairs which are not adjacent to each other
• Remove different strains from the list of genomes compared to

Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

1369 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	131	51
L domain-like	Protein kinase-like (PK-like)	122	31
L domain-like	L domain-like	81	40
RNA-binding domain, RBD	RNA-binding domain, RBD	67	18
P-loop containing nucleoside triphosphate hydrolases	L domain-like	57	20
TPR-like	TPR-like	52	18
RNI-like	L domain-like	46	32
F-box domain	RNI-like	46	8
GroES-like	NAD(P)-binding Rossmann-fold domains	43	6
Thioredoxin-like	GST C-terminal domain-like	39	6
ARM repeat	ARM repeat	38	27
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	38	7
Actin-like ATPase domain	Actin-like ATPase domain	37	15
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	36	5
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	36	10
RING/U-box	ARM repeat	34	11
RNI-like	Protein kinase-like (PK-like)	32	19
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	30	9
HAD-like	Calcium ATPase, transmembrane domain M	29	10
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	28	9
Thiolase-like	Thiolase-like	28	3
ABC transporter transmembrane region	ABC transporter transmembrane region	27	6
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	26	7
Calcium ATPase, transduction domain A	HAD-like	26	8
Cupredoxins	Cupredoxins	24	7
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	23	3
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	23	5
(Trans)glycosidases	Glycosyl hydrolase domain	22	12
GroEL equatorial domain-like	GroEL-intermediate domain like	22	6
F-box domain	Kelch motif	22	5
RNI-like	RNI-like	22	13
GroEL apical domain-like	GroEL-intermediate domain like	21	7
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	21	6
Periplasmic binding protein-like I	Periplasmic binding protein-like II	21	6
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	21	7
GroEL equatorial domain-like	GroEL apical domain-like	21	7
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	20	7
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	19	9
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	19	7
Cyclin-like	Cyclin-like	18	6
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	18	12
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	18	8
Calcium ATPase, transmembrane domain M	Metal cation-transporting ATPase, ATP-binding domain N	17	4
(Trans)glycosidases	Galactose-binding domain-like	17	8
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	16	4
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	16	11
RING/U-box	RING/U-box	16	14
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	16	10
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	16	7
Homeodomain-like	Homeodomain-like	15	9
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	15	3
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	15	3
CCCH zinc finger	CCCH zinc finger	15	12
Protein kinase-like (PK-like)	EF-hand	15	2
ENTH/VHS domain	GAT-like domain	15	4
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	15	4
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	15	3
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	14	3
Nucleic acid-binding proteins	Nucleic acid-binding proteins	14	11
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	13	8
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	13	5
HCP-like	HCP-like	13	6
Barwin-like endoglucanases	PHL pollen allergen	13	1
"Winged helix" DNA-binding domain	L domain-like	13	7
Toll/Interleukin receptor TIR domain	L domain-like	13	6
Thioredoxin-like	Thioredoxin-like	13	12
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	13	5
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	13	6
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	13	6
WD40 repeat-like	WD40 repeat-like	13	11
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	13	3
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	13	3
F-box domain	Galactose oxidase, central domain	12	3
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	12	7
FYVE/PHD zinc finger	FYVE/PHD zinc finger	11	9
Voltage-gated potassium channels	cAMP-binding domain-like	11	3
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	11	5
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	11	5
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	11	4
GroES-like	GroES-like	11	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	11	7
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	11	3
DNA-binding domain	DNA-binding domain	11	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	11	7
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	11	5
Protein kinase-like (PK-like)	ARM repeat	11	11
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	10	7
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	10	7
Toll/Interleukin receptor TIR domain	"Winged helix" DNA-binding domain	10	4
YhbY-like	YhbY-like	10	5
TPR-like	HCP-like	10	5
Ubiquitin-like	UBA-like	9	8
Phospholipase D/nuclease	Phospholipase D/nuclease	9	7
PAZ domain	Ribonuclease H-like	9	2
EF-G C-terminal domain-like	EF-G C-terminal domain-like	9	7
ARM repeat	WD40 repeat-like	9	9
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	9	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	9	4
Galactose-binding domain-like	Galactose-binding domain-like	9	3
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	9	9
SNARE-like	SNARE fusion complex	9	2
Homeodomain-like	Bet v1-like	9	4
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	9	4
ACT-like	ACT-like	9	6
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	9	2
dsRNA-binding domain-like	dsRNA-binding domain-like	9	7
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	9	2
DNA-binding pseudobarrel domain	CAD & PB1 domains	9	3
RING/U-box	WD40 repeat-like	8	6
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	8	7
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	8	4
BRCT domain	BRCT domain	8	8
Bet v1-like	Bet v1-like	8	4
Galactose oxidase, central domain	E set domains	8	2
Trypsin-like serine proteases	PDZ domain-like	8	4
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	8	5
Translation proteins	EF-G C-terminal domain-like	8	6
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	8	5
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	8	3
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	8	2
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	8	6
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	8	5
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	8	4
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	8	4
RING/U-box	FYVE/PHD zinc finger	8	8
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	8	5
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	8	5
Protein kinase-like (PK-like)	TPR-like	8	4
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	8	1
PK beta-barrel domain-like	PK C-terminal domain-like	8	2
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	7	4
CheY-like	Homeodomain-like	7	2
E set domains	(Trans)glycosidases	7	5
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	7	2
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	7	5
CBS-domain pair	CBS-domain pair	7	6
vWA-like	Helical domain of Sec23/24	7	4
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	7	3
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	7	1
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	7	5
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	7	6
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	7	5
beta-sandwich domain of Sec23/24	Zn-finger domain of Sec23/24	7	4
P-loop containing nucleoside triphosphate hydrolases	ARM repeat	7	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	7	4
Zn-finger domain of Sec23/24	vWA-like	7	4
RING/U-box	Nucleotide-diphospho-sugar transferases	7	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	7	5
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	7	4
Subtilisin-like	PA domain	7	2
Homodimeric domain of signal transducing histidine kinase	CheY-like	7	4
beta-sandwich domain of Sec23/24	vWA-like	7	4
CCCH zinc finger	RNA-binding domain, RBD	7	5
E set domains	Glycosyl hydrolase domain	7	5
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	7	7
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	7	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	7	4
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	6	5
MFS general substrate transporter	MFS general substrate transporter	6	2
P-loop containing nucleoside triphosphate hydrolases	E set domains	6	3
RING/U-box	TRAF domain-like	6	3
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	6	1
P-loop containing nucleoside triphosphate hydrolases	RNI-like	6	5
Single hybrid motif	CoA-dependent acyltransferases	6	4
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	6	5
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	6	3
Galactose mutarotase-like	(Trans)glycosidases	6	4
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	6	3
Enolase N-terminal domain-like	Enolase C-terminal domain-like	6	3
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	6	5
Chromo domain-like	Chromo domain-like	6	6
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	6	5
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	6	5
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	6	2
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	6	3
PreATP-grasp domain	Rudiment single hybrid motif	6	5
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	6	5
DNA/RNA polymerases	Ribonuclease H-like	6	4
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	6	5
Clc chloride channel	CBS-domain pair	6	3
PUA domain-like	SET domain	6	2
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	6	3
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	6	5
HMA, heavy metal-associated domain	HAD-like	6	5
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	6	3
Plant lectins/antimicrobial peptides	Lysozyme-like	6	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	6	4
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	6	3
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	6	3
PH domain-like	FYVE/PHD zinc finger	6	2
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	6	6
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	6	5
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	6	5
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	6	5
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	6	4
WRKY DNA-binding domain	WRKY DNA-binding domain	6	2
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	6	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	6	5
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	6	5
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	6	5
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	6	3
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	6	5
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	6	4
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	6	3
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	6	6
HAD-like	BRCT domain	6	2
PH domain-like	RCC1/BLIP-II	5	1
cAMP-binding domain-like	Ankyrin repeat	5	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	5	4
RCC1/BLIP-II	FYVE/PHD zinc finger	5	1
Homeodomain-like	FAD-linked reductases, C-terminal domain	5	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	5	4
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	5	5
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	5	4
EF-hand	Riboflavin synthase domain-like	5	1
ISP domain	Bet v1-like	5	2
FAS1 domain	FAS1 domain	5	2
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	5	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	5	3
Protein kinase-like (PK-like)	RING/U-box	5	4
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	5	2
Metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	5	3
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	5	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	5	3
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	5	5
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	5	2
Voltage-gated potassium channels	Ankyrin repeat	5	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	5	4
Cullin homology domain	"Winged helix" DNA-binding domain	5	4
RNase III domain-like	RNase III domain-like	5	5
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	5	3
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	5	1
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	5	1
Protein kinase-like (PK-like)	WD40 repeat-like	5	4
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	5	4
Translation proteins	Ribosomal protein S5 domain 2-like	5	4
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	5	4
FYVE/PHD zinc finger	Homeodomain-like	5	3
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	5	3
RING/U-box	vWA-like	5	2
Translation proteins SH3-like domain	Nucleic acid-binding proteins	5	3
Protein kinase-like (PK-like)	Ankyrin repeat	5	2
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	5	1
RNase III domain-like	dsRNA-binding domain-like	5	5
Homeodomain-like	FAD/NAD(P)-binding domain	5	2
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	5	3
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	5	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	5	3
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	5	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	5	5
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	5	4
Sec7 domain	ARM repeat	5	4
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	5	4
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	5	2
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	5	3
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	5	5
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	5	4
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	4	4
ARM repeat	TPR-like	4	3
Voltage-gated potassium channels	Voltage-gated potassium channels	4	3
CAD & PB1 domains	Protein kinase-like (PK-like)	4	1
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	4	2
EF-hand	EF-hand	4	4
TAZ domain	RING/U-box	4	4
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	4	4
UBA-like	UBA-like	4	4
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	4	3
Galactose mutarotase-like	Glycosyl hydrolase domain	4	2
RCC1/BLIP-II	RCC1/BLIP-II	4	1
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	4	2
ARID-like	HMG-box	4	2
Translational machinery components	L30e-like	4	2
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	4	2
EGF/Laminin	Protein kinase-like (PK-like)	4	2
FKBP-like	TPR-like	4	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	4	2
TRAF domain-like	POZ domain	4	1
Periplasmic binding protein-like II	ACT-like	4	2
RING/U-box	Cysteine proteinases	4	4
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	4	3
BEACH domain	WD40 repeat-like	4	4
ClpP/crotonase	ClpP/crotonase	4	3
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	4	4
ARM repeat	Clathrin adaptor appendage domain	4	4
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	4	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	4	4
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	4	4
Zinc hairpin stack	RING/U-box	4	3
PAZ domain	RNase III domain-like	4	4
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	4	4
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	3
WW domain	WW domain	4	4
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	4	3
E set domains	Ankyrin repeat	4	1
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	4	2
Actin-crosslinking proteins	(Trans)glycosidases	4	1
Acid proteases	Acid proteases	4	2
HD-domain/PDEase-like	Nucleotidyltransferase	4	4
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	4	3
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	4	1
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	4	3
FYVE/PHD zinc finger	SET domain	4	4
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	4	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	4
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	4	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	4	4
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	4	4
ARM repeat	Hect, E3 ligase catalytic domain	4	4
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	3
F-box domain	WD40 repeat-like	4	3
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	4	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	4	1
TPR-like	Thioredoxin-like	4	4
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	4	3
Cullin repeat-like	Cullin homology domain	3	2
CHY zinc finger-like	RING/U-box	3	2
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	3	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	3	3
POZ domain	TAZ domain	3	2
BAR/IMD domain-like	SH3-domain	3	1
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	3	3
DUSP-like	Cysteine proteinases	3	2
(Trans)glycosidases	beta-Galactosidase/glucuronidase domain	3	3
PA domain	Transferrin receptor-like dimerisation domain	3	1
PH domain-like	Oxysterol-binding protein-like	3	2
Thioredoxin-like	Cysteine-rich domain	3	3
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	3	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	2
Ubiquitin-like	Zn-binding ribosomal proteins	3	1
RCC1/BLIP-II	Protein kinase-like (PK-like)	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	3	2
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	2
Thioredoxin-like	Ubiquitin-like	3	2
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	3	3
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	3	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	3	2
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	3	1
F-box domain	Tubby C-terminal domain-like	3	2
Ankyrin repeat	RING/U-box	3	2
ARM repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	3	3
SAP domain	RNA-binding domain, RBD	3	2
Nucleotidylyl transferase	Nucleotidylyl transferase	3	1
Aldolase	NAD(P)-binding Rossmann-fold domains	3	2
Actin depolymerizing proteins	Actin depolymerizing proteins	3	2
Cullin repeat-like	"Winged helix" DNA-binding domain	3	2
POZ domain	POZ domain	3	3
GroEL apical domain-like	SAICAR synthase-like	3	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	3	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	3	2
TPR-like	Chaperone J-domain	3	3
Translation proteins	Translation proteins	3	2
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	3	1
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	3	2
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	3	3
BRCT domain	RING/U-box	3	3
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	3	2
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	3	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	2
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	3	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	3	2
BEACH domain	ARM repeat	3	3
FKBP-like	FKBP-like	3	1
Voltage-gated potassium channels	EF-hand	3	3
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	3	1
POZ domain	Ankyrin repeat	3	2
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	3	2
RING/U-box	UBA-like	3	3
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	3	2
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	3	1
Ankyrin repeat	Ankyrin repeat	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	3	2
Cysteine proteinases	Granulin repeat	3	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	3	3
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	3	1
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	3	3
Periplasmic binding protein-like I	Voltage-gated potassium channels	3	3
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	3	2
PH domain-like	BEACH domain	3	3
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	3	2
Voltage-gated potassium channels	Periplasmic binding protein-like II	3	3
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	3	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	3	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	3	1
ARM repeat	PH domain-like	3	3
RNA-binding domain, RBD	PABC (PABP) domain	3	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	3	2
Arp2/3 complex subunits	Arp2/3 complex subunits	3	2
PH domain-like	WD40 repeat-like	3	3
NAD(P)-binding Rossmann-fold domains	ACT-like	3	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	1
PA domain	Zn-dependent exopeptidases	3	1
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	3	3
FF domain	FF domain	3	3
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	3	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	3	1
PUA domain-like	Nucleotidylyl transferase	3	2
PAZ domain	dsRNA-binding domain-like	3	3
PYP-like sensor domain (PAS domain)	GAF domain-like	3	3
SET domain	Tudor/PWWP/MBT	3	3
GAF domain-like	GAF domain-like	3	3
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	3	1
UBC-like	Endosomal sorting complex assembly domain	3	1
TAZ domain	FYVE/PHD zinc finger	3	3
WGR domain-like	ADP-ribosylation	3	2
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	3	2
NTF2-like	RNA-binding domain, RBD	3	1
Ubiquitin-like	BAG domain	3	1
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	3	2
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	3
Tudor/PWWP/MBT	FYVE/PHD zinc finger	3	3
Protein kinase-like (PK-like)	PP2C-like	3	3
UBC-like	RING/U-box	3	3
Sec63 N-terminal domain-like	E set domains	3	3
ARM repeat	Subdomain of clathrin and coatomer appendage domain	3	3
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	3	2
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	3	1
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	3	1
TPR-like	SET domain	3	2
PDZ domain-like	ClpP/crotonase	3	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	3	2
Translation proteins SH3-like domain	Translation proteins SH3-like domain	3	3
Cysteine-rich domain	Cysteine-rich domain	3	2
FYVE/PHD zinc finger	Chromo domain-like	3	3
Translation proteins	Initiation factor IF2/eIF5b, domain 3	3	2
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	3	3
Translation proteins	ThrRS/AlaRS common domain	3	3
TPR-like	CAD & PB1 domains	3	1
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	3	3
CHY zinc finger-like	Zinc hairpin stack	3	2
ADC-like	Cdc48 domain 2-like	3	2
Ribosomal protein L6	Ribosomal protein L6	3	2
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	3	2
Dihydrofolate reductase-like	YbiA-like	2	2
LEA14-like	LEA14-like	2	1
Ubiquitin-like	XPC-binding domain	2	2
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	2	1
WW domain	FF domain	2	2
LysM domain	LysM domain	2	1
Saposin	Saposin	2	2
UROD/MetE-like	UROD/MetE-like	2	2
PUA domain-like	Ribosomal protein S5 domain 2-like	2	2
AN1-like Zinc finger	AN1-like Zinc finger	2	2
Thioredoxin-like	"Winged helix" DNA-binding domain	2	1
CheY-like	CheY-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	2	2
DEK C-terminal domain	SWIB/MDM2 domain	2	2
FAD/NAD(P)-binding domain	EF-hand	2	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	2	1
PYP-like sensor domain (PAS domain)	F-box domain	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	2
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	1
PH domain-like	Ankyrin repeat	2	2
PH domain-like	ArfGap/RecO-like zinc finger	2	2
Smc hinge domain	Myosin rod fragments	2	2
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	2	1
Class II aaRS ABD-related	C-terminal domain of ProRS	2	2
PreATP-grasp domain	Single hybrid motif	2	2
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	2	2
ARM repeat	Concanavalin A-like lectins/glucanases	2	2
GroEL equatorial domain-like	GroEL equatorial domain-like	2	2
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	2	1
(Phosphotyrosine protein) phosphatases II	E set domains	2	2
Nucleic acid-binding proteins	Ribonuclease H-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	2	1
EF-hand	P-loop containing nucleoside triphosphate hydrolases	2	2
Galactose mutarotase-like	Galactose-binding domain-like	2	2
RING/U-box	Homeodomain-like	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	2
SAP domain	ADP-ribosylation	2	1
PH domain-like	Bet v1-like	2	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	2	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	2	2
SWIB/MDM2 domain	SWIB/MDM2 domain	2	2
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Homeodomain-like	"Winged helix" DNA-binding domain	2	2
F-box domain	L domain-like	2	2
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	2	2
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	2	2
Cytochrome P450	Cytochrome P450	2	2
Chaperone J-domain	Thioredoxin-like	2	2
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	2	2
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	1
RNA-binding domain, RBD	Ribonuclease H-like	2	2
POZ domain	TPR-like	2	1
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	2	2
BRCT domain	FYVE/PHD zinc finger	2	2
UBA-like	XPC-binding domain	2	2
SWIB/MDM2 domain	Plus3-like	2	2
Retrovirus zinc finger-like domains	RING/U-box	2	2
TATA-box binding protein-like	TATA-box binding protein-like	2	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	2	2
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	2	2
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	2	2
Carbamate kinase-like	ACT-like	2	2
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	2	2
Aconitase iron-sulfur domain	LeuD/IlvD-like	2	2
FYVE/PHD zinc finger	GroEL apical domain-like	2	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
BAR/IMD domain-like	PH domain-like	2	2
HIT/MYND zinc finger-like	Cysteine proteinases	2	1
FYVE/PHD zinc finger	SAICAR synthase-like	2	1
Ubiquitin-like	Cysteine proteinases	2	2
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
Galactose-binding domain-like	NAD(P)-binding Rossmann-fold domains	2	2
Clavaminate synthase-like	beta-beta-alpha zinc fingers	2	2
Kelch motif	Kelch motif	2	2
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	2	1
PGBD-like	Metalloproteases ("zincins"), catalytic domain	2	1
E set domains	E set domains	2	2
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	2	1
ACT-like	Protein kinase-like (PK-like)	2	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	2	2
Ubiquitin-like	PUG domain-like	2	2
DNA clamp	DNA clamp	2	1
CCCH zinc finger	RING/U-box	2	2
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
PLP-dependent transferases	PLP-dependent transferases	2	2
PLC-like phosphodiesterases	PLC-like phosphodiesterases	2	1
F-box domain	Clavaminate synthase-like	2	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	2	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	2	2
PriA/YqbF domain	GINS helical bundle-like	2	2
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	2
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	2	2
UBA-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	2	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	2	2
Acetyl-CoA synthetase-like	ACP-like	2	2
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	2	2
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	2	1
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	2	1
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	2	1
Class II aaRS and biotin synthetases	Translation proteins	2	2
SNARE-like	Domain of the SRP/SRP receptor G-proteins	2	1
Six-hairpin glycosidases	AbfB domain	2	1
Ubiquitin-like	Homeodomain-like	2	1
Amine oxidase N-terminal region	Amine oxidase catalytic domain	2	1
Chaperone J-domain	4Fe-4S ferredoxins	2	2
Clavaminate synthase-like	Clavaminate synthase-like	2	1
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	2	2
Restriction endonuclease-like	RuvA domain 2-like	2	2
ARM repeat	Tudor/PWWP/MBT	2	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	2	1
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	2	2
Concanavalin A-like lectins/glucanases	PH domain-like	2	2
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
RNA-binding domain, RBD	Ran binding protein zinc finger-like	2	2
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	2	2
RuBisCO, large subunit, small (N-terminal) domain	RuBisCo, C-terminal domain	2	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	2	2
SMAD/FHA domain	Phospholipase D/nuclease	2	2
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	2	2
Ribonuclease H-like	HRDC-like	2	2
Amidase signature (AS) enzymes	TPR-like	2	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	2	2
SAP domain	WGR domain-like	2	1
Amine oxidase N-terminal region	Amine oxidase N-terminal region	2	1
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	2	2
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	2	1
RING/U-box	RNA-binding domain, RBD	2	2
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	2
PH domain-like	GTPase activation domain, GAP	2	1
ArfGap/RecO-like zinc finger	Ankyrin repeat	2	2
Protease propeptides/inhibitors	Subtilisin-like	2	2
SBT domain	Ankyrin repeat	2	1
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
Alpha-L RNA-binding motif	Pseudouridine synthase	2	2
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	2
PRTase-like	PRTase-like	2	2
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	2
L domain-like	Outer arm dynein light chain 1	2	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
PurM N-terminal domain-like	PurM C-terminal domain-like	2	2
t-snare proteins	SNARE fusion complex	2	2
(Trans)glycosidases	Chitinase insertion domain	2	1
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	2	2
CBS-domain pair	CAD & PB1 domains	2	2
GAF domain-like	CheY-like	2	1
Starch-binding domain-like	Galactose-binding domain-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	2	2
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	1
UBA-like	Thioredoxin-like	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	2	1
GYF domain	SET domain	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	1
ARM repeat	POZ domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	2	2
EF-hand	PLC-like phosphodiesterases	2	1
TPR-like	RING/U-box	2	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
Ribosomal L27 protein-like	Nucleic acid-binding proteins	2	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	2	1
ISP transmembrane anchor	ISP domain	2	1
POZ domain	WD40 repeat-like	2	2
Myosin rod fragments	P-loop containing nucleoside triphosphate hydrolases	2	2
UBA-like	Hect, E3 ligase catalytic domain	2	2
Adenine nucleotide alpha hydrolases-like	RING/U-box	2	1
beta-beta-alpha zinc fingers	Ribonuclease H-like	2	2
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	2	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	2	1
Trypsin-like serine proteases	Trypsin-like serine proteases	2	2
Soluble quinoprotein glucose dehydrogenase	WD40 repeat-like	2	2
PreATP-grasp domain	PreATP-grasp domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	2	1
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	2	2
vWA-like	SPOC domain-like	2	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	2
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	2	2
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	2	1
LysM domain	Protein kinase-like (PK-like)	2	1
F-box domain	HCP-like	2	2
E set domains	AMPKBI-like	2	1
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
PX domain	BAR/IMD domain-like	2	2
YrdC/RibB	RibA-like	2	2
Surp module (SWAP domain)	Surp module (SWAP domain)	2	2
Hypothetical protein c14orf129, hspc210	TPR-like	2	1
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	2	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	2	2
Cysteine proteinases	UBA-like	2	2
Kelch motif	Metallo-dependent phosphatases	2	2
SAP domain	SAP domain	2	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	2	1
Acid proteases	Saposin	2	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
ARM repeat	UBA-like	2	2
Dom34/Pelota N-terminal domain-like	L30e-like	2	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Ribonuclease H-like	RING/U-box	2	2
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	2	2
POZ domain	Skp1 dimerisation domain-like	2	2
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	2	1
Serine metabolism enzymes domain	ACT-like	2	2
Cystatin/monellin	Cystatin/monellin	2	1
L9 N-domain-like	Ribosomal protein L9 C-domain	2	2
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	2
EF-hand	Mitochondrial carrier	2	2
BAR/IMD domain-like	Ankyrin repeat	2	2
PA domain	RING/U-box	2	2
Dom34/Pelota N-terminal domain-like	Translational machinery components	2	1
ARID-like	FYVE/PHD zinc finger	2	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	2	1
Oxidoreductase molybdopterin-binding domain	E set domains	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	1
SAP domain	Domain of poly(ADP-ribose) polymerase	2	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	2	1
RING/U-box	PUA domain-like	2	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	2	1
Rudiment single hybrid motif	Single hybrid motif	2	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
Metalloproteases ("zincins"), catalytic domain	HAD-like	2	2
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	2	2
PH domain-like	BSD domain-like	1	1
Tex N-terminal region-like	SH2 domain	1	1
DNA-glycosylase	Nudix	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
FAD-linked oxidases, C-terminal domain	FAD-linked oxidases, C-terminal domain	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
Zinc beta-ribbon	Cyclin-like	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Staphylococcal nuclease	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
ARM repeat	Clavaminate synthase-like	1	1
Ubiquitin-like	Cap-Gly domain	1	1
DPP6 N-terminal domain-like	DPP6 N-terminal domain-like	1	1
Hypothetical protein PA1324	Carboxypeptidase regulatory domain-like	1	1
Concanavalin A-like lectins/glucanases	SH2 domain	1	1
E set domains	CBS-domain pair	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
GST C-terminal domain-like	eEF-1beta-like	1	1
CCCH zinc finger	WD40 repeat-like	1	1
E set domains	Riboflavin synthase domain-like	1	1
SMAD/FHA domain	PP2C-like	1	1
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	1	1
HLH, helix-loop-helix DNA-binding domain	Formin homology 2 domain (FH2 domain)	1	1
Nucleic acid-binding proteins	UBA-like	1	1
Phospholipase C/P1 nuclease	Phospholipase C/P1 nuclease	1	1
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Signal peptide-binding domain	Sec-C motif	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
CAD & PB1 domains	RING/U-box	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Second domain of FERM	PH domain-like	1	1
Nucleotidyltransferase	TGS-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	MHC antigen-recognition domain	1	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
Cytidine deaminase-like	Cytidine deaminase-like	1	1
Carbamate kinase-like	ALDH-like	1	1
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	1	1
Chaperone J-domain	FAD/NAD(P)-binding domain	1	1
PreATP-grasp domain	ClpP/crotonase	1	1
P-loop containing nucleoside triphosphate hydrolases	Ribosomal L11/L12e N-terminal domain	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
NAD kinase/diacylglycerol kinase-like	NAD kinase/diacylglycerol kinase-like	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	1	1
RNI-like	Outer arm dynein light chain 1	1	1
Thioredoxin-like	FAD-dependent thiol oxidase	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	1	1
Rudiment single hybrid motif	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Pseudouridine synthase	Pseudouridine synthase	1	1
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	1	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	F1F0 ATP synthase subunit A	1	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
SAP domain	DNase I-like	1	1
TPR-like	HSP20-like chaperones	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	1	1
GYF domain	RNA-binding domain, RBD	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
FYVE/PHD zinc finger	Bromodomain	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Acid proteases	DNA/RNA polymerases	1	1
ARM repeat	SH3-domain	1	1
FAD/NAD(P)-binding domain	NAD(P)-binding Rossmann-fold domains	1	1
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
F-box domain	Protein kinase-like (PK-like)	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
F-box domain	SET domain	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Metalloproteases ("zincins"), catalytic domain	ARM repeat	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
P-loop containing nucleoside triphosphate hydrolases	vWA-like	1	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	1	1
alpha-D-mannose-specific plant lectins	EGF/Laminin	1	1
Ribosomal protein S2	F1F0 ATP synthase subunit A	1	1
DAK1/DegV-like	DhaL-like	1	1
UraD-Like	Transthyretin (synonym: prealbumin)	1	1
L30e-like	alpha/beta knot	1	1
SH2 domain	SH2 domain	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
Chaperone J-domain	Homeodomain-like	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
DNase I-like	DNase I-like	1	1
PAH2 domain	PAH2 domain	1	1
Galactose-binding domain-like	ARM repeat	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
Rhomboid-like	UBA-like	1	1
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	1	1
ARID-like	Clavaminate synthase-like	1	1
F-box domain	SMI1/KNR4-like	1	1
Prokaryotic type I DNA topoisomerase	Retrovirus zinc finger-like domains	1	1
Protein prenylyltransferase	L domain-like	1	1
SSo0622-like	Kelch motif	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	1	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
Trimeric LpxA-like enzymes	Ribosomal protein S5 domain 2-like	1	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	1	1
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
Plus3-like	GYF domain	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
PDZ domain-like	E set domains	1	1
UBA-like	post-AAA+ oligomerization domain-like	1	1
Class I glutamine amidotransferase-like	ADC synthase	1	1
GYF domain	CCCH zinc finger	1	1
TPR-like	PH domain-like	1	1
Tubulin nucleotide-binding domain-like	Protein kinase-like (PK-like)	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
CarD-like	TRCF domain-like	1	1
Cyclophilin-like	RNA-binding domain, RBD	1	1
BSD domain-like	BSD domain-like	1	1
Cap-Gly domain	L domain-like	1	1
UBA-like	PUG domain-like	1	1
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Acyl-CoA binding protein	Galactose oxidase, central domain	1	1
PLP-dependent transferases	ARM repeat	1	1
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
RNI-like	ARM repeat	1	1
GYF domain	F-box domain	1	1
Ankyrin repeat	CCCH zinc finger	1	1
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
EF-hand	TPR-like	1	1
Chromo domain-like	Homeodomain-like	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
RNA-binding domain, RBD	HCP-like	1	1
Macro domain-like	CRAL/TRIO domain	1	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	1	1
HAD-like	HAD-like	1	1
cAMP-binding domain-like	cAMP-binding domain-like	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	1	1
RING/U-box	Ran binding protein zinc finger-like	1	1
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
PP2C-like	cAMP-binding domain-like	1	1
Mannose-binding lectins	Mannose-binding lectins	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
SufE/NifU	NadA-like	1	1
Cation efflux protein cytoplasmic domain-like	Cation efflux protein cytoplasmic domain-like	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Galactose oxidase, central domain	Galactose oxidase, central domain	1	1
Cysteine proteinases	Formin homology 2 domain (FH2 domain)	1	1
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Cupredoxins	FtsH protease domain-like	1	1
Arabinanase/levansucrase/invertase	Arabinanase/levansucrase/invertase	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	1	1
HisI-like	all-alpha NTP pyrophosphatases	1	1
Beta-D-glucan exohydrolase, C-terminal domain	Beta-D-glucan exohydrolase, C-terminal domain	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	1	1
WWE domain	ADP-ribosylation	1	1
Chromo domain-like	Ankyrin repeat	1	1
DHH phosphoesterases	DHH phosphoesterases	1	1
PP2C-like	PP2C-like	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
TGS-like	Class II aaRS ABD-related	1	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
CCCH zinc finger	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
BRCT domain	WGR domain-like	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
GroES-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
RmlC-like cupins	RmlC-like cupins	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
PH domain-like	Phospholipase D/nuclease	1	1
Tudor/PWWP/MBT	RNA-binding domain, RBD	1	1
Protein kinase-like (PK-like)	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	1	1
WD40 repeat-like	TolB, C-terminal domain	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
Ubiquitin-like	Ubiquitin-like	1	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
Cytidine deaminase-like	Dihydrofolate reductase-like	1	1
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
TAZ domain	TAZ domain	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	1	1
Chaperone J-domain	ARM repeat	1	1
RNA-binding domain, RBD	WW domain	1	1
PYP-like sensor domain (PAS domain)	Kelch motif	1	1
L domain-like	ARM repeat	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
TPR-like	PUA domain-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Tropomyosin	Apolipoprotein A-I	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	1	1
R3H domain	Ankyrin repeat	1	1
4Fe-4S ferredoxins	Metallo-hydrolase/oxidoreductase	1	1
YgbK-like	Aldolase	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
SET domain	SET domain	1	1
DEK C-terminal domain	ssDNA-binding transcriptional regulator domain	1	1
SWIB/MDM2 domain	eIF1-like	1	1
FAD/NAD(P)-binding domain	alpha/beta-Hydrolases	1	1
PIN domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
TPR-like	RNI-like	1	1
FYVE/PHD zinc finger	TPR-like	1	1
BRCT domain	Nucleotidyltransferase	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
TPR-like	Cysteine proteinases	1	1
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	1	1
P-loop containing nucleoside triphosphate hydrolases	CCCH zinc finger	1	1
RING/U-box	Cysteine-rich domain	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	1	1
PurS-like	PurM C-terminal domain-like	1	1
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	1	1
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	1	1
Ankyrin repeat	RNA-binding domain, RBD	1	1
F-box domain	Cullin repeat-like	1	1
Thioredoxin-like	VC0467-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	1	1
F-box domain	ARM repeat	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	1	1
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	1	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
RNA-binding domain, RBD	ENTH/VHS domain	1	1
RING/U-box	Cyclophilin-like	1	1
TPR-like	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	1	1
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	1	1
HCP-like	Thioredoxin-like	1	1
Pseudouridine synthase	PUA domain-like	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	1	1
Nucleoside hydrolase	Nucleoside hydrolase	1	1
Thioredoxin-like	ERP29 C domain-like	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
E set domains	Cytochrome b5-like heme/steroid binding domain	1	1
Ubiquitin-like	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HIT-like	1	1
Single hybrid motif	ClpP/crotonase	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
GAF domain-like	HLH, helix-loop-helix DNA-binding domain	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
GST C-terminal domain-like	Nucleic acid-binding proteins	1	1
Ubiquitin-like	Acid proteases	1	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Tropomyosin	Mitotic arrest deficient-like 1, Mad1	1	1
F-box domain	Pectin lyase-like	1	1
L domain-like	FabD/lysophospholipase-like	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
Cyclophilin-like	TPR-like	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
ACT-like	Formyltransferase	1	1
Hypothetical protein PA1324	Starch-binding domain-like	1	1
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	1	1
Heme oxygenase-like	HAD-like	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
Cytidine deaminase-like	YbiA-like	1	1
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	1	1
HAD-like	dsRNA-binding domain-like	1	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	1	1
CAD & PB1 domains	UBA-like	1	1
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Chaperone J-domain	E set domains	1	1
SMAD/FHA domain	PIN domain-like	1	1
TRAF domain-like	TRAF domain-like	1	1
Nucleotidyltransferase	EF-hand	1	1
Clathrin heavy-chain terminal domain	ARM repeat	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
GroEL-intermediate domain like	SAICAR synthase-like	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Ubiquitin-like	Bromodomain	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
UBC-like	Class II aaRS ABD-related	1	1
Macro domain-like	HIT-like	1	1
Chaperone J-domain	RNA-binding domain, RBD	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	1	1
PDZ domain-like	Rubredoxin-like	1	1
Glutathione synthetase ATP-binding domain-like	PK beta-barrel domain-like	1	1
Rudiment single hybrid motif	ClpP/crotonase	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
FYVE/PHD zinc finger	Plus3-like	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
YjgF-like	YjgF-like	1	1
P-loop containing nucleoside triphosphate hydrolases	VC0467-like	1	1
Actin-like ATPase domain	AF1104-like	1	1
FYVE/PHD zinc finger	SWIB/MDM2 domain	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
BRCT domain	ADP-ribosylation	1	1
HCP-like	HIT/MYND zinc finger-like	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
HAD-like	Riboflavin kinase-like	1	1
WD40 repeat-like	DNase I-like	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
"Winged helix" DNA-binding domain	Zinc beta-ribbon	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
Galactose mutarotase-like	Starch-binding domain-like	1	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
ACP-like	Heme-dependent catalase-like	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	1	1
MHC antigen-recognition domain	Protein kinase-like (PK-like)	1	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	1	1
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	1	1
Chelatase	Chlorophyll a-b binding protein	1	1
dsRNA-binding domain-like	Intermediate filament protein, coiled coil region	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
POZ domain	Galactose-binding domain-like	1	1
Histone-fold	ARM repeat	1	1
F-box domain	ApaG-like	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
HIT-like	HIT-like	1	1
Hypothetical protein AF0491, middle domain	beta-beta-alpha zinc fingers	1	1
vWA-like	SAP domain	1	1
Ribose/Galactose isomerase RpiB/AlsB	RmlC-like cupins	1	1
Mannose 6-phosphate receptor domain	ARM repeat	1	1
Aspartate/glutamate racemase	Aspartate/glutamate racemase	1	1
CCCH zinc finger	ARM repeat	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
PRP4-like	WD40 repeat-like	1	1
PUA domain-like	alpha/beta knot	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
Nucleotidylyl transferase	tRNA-binding arm	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
BRCT domain	DNA/RNA polymerases	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
Ricin B-like lectins	Glycosyl hydrolase domain	1	1
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	1	1
Lipocalins	Lipocalins	1	1
Enolase N-terminal domain-like	alpha/beta-Hydrolases	1	1
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	1	1
FAD-linked oxidoreductase	P-loop containing nucleoside triphosphate hydrolases	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
Starch-binding domain-like	Nucleic acid-binding proteins	1	1
Granulin repeat	Formin homology 2 domain (FH2 domain)	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	1	1
Urease, gamma-subunit	Metallo-dependent hydrolases	1	1
Glutathione synthetase ATP-binding domain-like	PK C-terminal domain-like	1	1
UBC-like	UBA-like	1	1
BAH domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Cytochrome f, large domain	Rudiment single hybrid motif	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	TPR-like	1	1
ARID-like	HSP20-like chaperones	1	1
L-aspartase-like	Class II aaRS ABD-related	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
WD40 repeat-like	NHL repeat	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
ARM repeat	alpha/beta knot	1	1
SNARE fusion complex	SNARE fusion complex	1	1
Ubiquitin-like	L domain-like	1	1
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	1	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
HCP-like	SMR domain-like	1	1
(Trans)glycosidases	Ricin B-like lectins	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Quinoprotein alcohol dehydrogenase-like	ARM repeat	1	1
POZ domain	Pentapeptide repeat-like	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	1	1
F-box domain	LysM domain	1	1
SMI1/KNR4-like	ApaG-like	1	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	1	1
WD40 repeat-like	DPP6 N-terminal domain-like	1	1
"Winged helix" DNA-binding domain	E set domains	1	1
RuvA domain 2-like	SH2 domain	1	1
Starch-binding domain-like	Phosphoglycerate mutase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	S13-like H2TH domain	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
ACP-like	Quinoprotein alcohol dehydrogenase-like	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Flavoproteins	Radical SAM enzymes	1	1
WD40 repeat-like	Calcium-dependent phosphotriesterase	1	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	1	1
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
WD40 repeat-like	Tricorn protease domain 2	1	1
FYVE/PHD zinc finger	Retrovirus zinc finger-like domains	1	1
Ubiquitin-like	TPR-like	1	1
Cysteine-rich domain	BRCT domain	1	1
Acid proteases	UBA-like	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	AF1104-like	1	1
E set domains	RNA-binding domain, RBD	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
Cysteine proteinases	Sec-C motif	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	1	1
Ribonuclease H-like	Ribonuclease H-like	1	1
PurS-like	PurM N-terminal domain-like	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	1	1
HAD-like	NTF2-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
ENT-like	Tudor/PWWP/MBT	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
Ubiquitin-like	Protein kinase-like (PK-like)	1	1
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	1	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Protein kinase-like (PK-like)	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Ubiquitin-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Pre-PUA domain	PUA domain-like	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
Clavaminate synthase-like	RING/U-box	1	1
UBA-like	KA1-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Formin homology 2 domain (FH2 domain)	1	1
MHC antigen-recognition domain	ARM repeat	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	L30e-like	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	PLP-dependent transferases	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
SWIB/MDM2 domain	GYF domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Epsilon subunit of F1F0-ATP synthase N-terminal domain	1	1
HMG-box	HMG-box	1	1
PapD-like	Ankyrin repeat	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	Ribosomal protein S2	1	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
HD-domain/PDEase-like	TGS-like	1	1
vWA-like	Cysteine-rich domain	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Ankyrin repeat	TPR-like	1	1
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	1	1
YjeF N-terminal domain-like	FMN-binding split barrel	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	1	1
HD-domain/PDEase-like	ACT-like	1	1
SPOC domain-like	SAP domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
Nucleotidyltransferase	ACT-like	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
MFS general substrate transporter	HMA, heavy metal-associated domain	1	1
HD-domain/PDEase-like	EF-hand	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
Translation proteins	PRC-barrel domain	1	1
WD40 repeat-like	Bromodomain	1	1
Dcp2 domain-like	Nudix	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
DNase I-like	EF-hand	1	1
FYVE/PHD zinc finger	ARM repeat	1	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
DUSP-like	Ubiquitin-like	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
RNA-binding domain, RBD	PWI domain	1	1
Actin-like ATPase domain	HD-domain/PDEase-like	1	1
Protein kinase-like (PK-like)	UBA-like	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
Tudor/PWWP/MBT	Chromo domain-like	1	1
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	1	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
Starch-binding domain-like	Carboxypeptidase regulatory domain-like	1	1
PIN domain-like	PLP-dependent transferases	1	1
PDZ domain-like	PDZ domain-like	1	1
NAD(P)-binding Rossmann-fold domains	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
PUA domain-like	eIF1-like	1	1
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Quinoprotein alcohol dehydrogenase-like	DNase I-like	1	1
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Carbamate kinase-like	Carbamate kinase-like	1	1
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
Starch-binding domain-like	Cna protein B-type domain	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	1	1
FKBP-like	Triger factor/SurA peptide-binding domain-like	1	1
Concanavalin A-like lectins/glucanases	Cysteine proteinases	1	1
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
TGS-like	ACT-like	1	1
Taf5 N-terminal domain-like	WD40 repeat-like	1	1
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	1	1
Cysteine proteinases	SET domain	1	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	1	1
SWIB/MDM2 domain	CCCH zinc finger	1	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	1	1
SAP domain	FYVE/PHD zinc finger	1	1
Cytochrome f, large domain	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	1	1
FYSH domain	beta-beta-alpha zinc fingers	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
FKBP-like	Rhodanese/Cell cycle control phosphatase	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
EF-hand	Metallo-dependent phosphatases	1	1
Trimeric LpxA-like enzymes	GHMP Kinase, C-terminal domain	1	1
RL5-like	Glucocorticoid receptor-like (DNA-binding domain)	1	1
SMAD/FHA domain	BRCT domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein L11, C-terminal domain	1	1
Flavoproteins	Riboflavin synthase domain-like	1	1
PH domain-like	HMG-box	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	1	1
F-box domain	HIT/MYND zinc finger-like	1	1
HydA/Nqo6-like	Nqo5-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	1	1
ARM repeat	"Winged helix" DNA-binding domain	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
PDZ domain-like	TPR-like	1	1
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	1	1
S13-like H2TH domain	Ribosomal protein S5 domain 2-like	1	1
BRCT domain	PsbU/PolX domain-like	1	1
TPR-like	"Winged helix" DNA-binding domain	1	1
F-box domain	Actin-like ATPase domain	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
SufE/NifU	BolA-like	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
WD40 repeat-like	TPR-like	1	1
Thioredoxin-like	NHL repeat	1	1
TPR-like	Metallo-dependent phosphatases	1	1
HCP-like	Pseudo ankyrin repeat-like	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Hypothetical protein PA1324	Cna protein B-type domain	1	1
FAD/NAD(P)-binding domain	ACP-like	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
Plus3-like	CCCH zinc finger	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	1	1
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	1	1
Tropomyosin	Tropomyosin	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	1	1
DNA-binding domain	DNA-binding pseudobarrel domain	1	1
F-box domain	NTF2-like	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
HAD-like	Thioredoxin-like	1	1
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
Spermadhesin, CUB domain	Protein kinase-like (PK-like)	1	1
L-aspartase-like	Class II aaRS and biotin synthetases	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	1	1
Carboxypeptidase regulatory domain-like	Cna protein B-type domain	1	1
Protein kinase-like (PK-like)	KA1-like	1	1
Ribonuclease H-like	SH2 domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	1	1
"Winged helix" DNA-binding domain	RNI-like	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
P-loop containing nucleoside triphosphate hydrolases	Thioredoxin-like	1	1
P-loop containing nucleoside triphosphate hydrolases	(Trans)glycosidases	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
HAD-like	NHL repeat	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
Trigger factor ribosome-binding domain	FKBP-like	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Chaperone J-domain	CSL zinc finger	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	1	1
ACP-like	Trimeric LpxA-like enzymes	1	1
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1