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Domain combination pairs in Candidatus Midichloria mitochondrii IricVA

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

284 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Actin-like ATPase domain Actin-like ATPase domain 63
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 55
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 52
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 53
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 54
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 52
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 43
P-loop containing nucleoside triphosphate hydrolases Translation proteins 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 33
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 32
FKBP-like Triger factor/SurA peptide-binding domain-like 33
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 22
Trypsin-like serine proteases PDZ domain-like 22
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Nucleic acid-binding proteins RuvA domain 2-like 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 21
CBS-domain pair FAD-binding/transporter-associated domain-like 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
Carbamate kinase-like ACT-like 22
Alpha-L RNA-binding motif Pseudouridine synthase 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 22
CheY-like P-loop containing nucleoside triphosphate hydrolases 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Translation proteins EF-G C-terminal domain-like 22
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
CheY-like C-terminal effector domain of the bipartite response regulators 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 22
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 22
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Lysozyme-like beta-lactamase/transpeptidase-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
CheY-like Homeodomain-like 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
FliG FliG 11
PreATP-grasp domain Single hybrid motif 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
Formyltransferase FMT C-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
GroEL equatorial domain-like GroEL apical domain-like 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Thiolase-like Thiolase-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
P-loop containing nucleoside triphosphate hydrolases Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
PUA domain-like alpha/beta knot 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Single hybrid motif CoA-dependent acyltransferases 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
TGS-like ThrRS/AlaRS common domain 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
PheT/TilS domain Putative DNA-binding domain 11
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
PIN domain-like Ribonuclease H-like 11
HAD-like Calcium ATPase, transmembrane domain M 11
Flagellar hook protein flgE Flagellar hook protein flgE 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
DNA clamp DNA clamp 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Calcium ATPase, transduction domain A HAD-like 11
HMA, heavy metal-associated domain HAD-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
PDZ domain-like PDZ domain-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Ribosomal protein L6 Ribosomal protein L6 11
Translation proteins ThrRS/AlaRS common domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Nucleotide-binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 11
TGS-like Class II aaRS and biotin synthetases 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
HD-domain/PDEase-like TGS-like 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
Rudiment single hybrid motif Single hybrid motif 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Nucleic acid-binding proteins BRCT domain 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
N-terminal domain of the delta subunit of the F1F0-ATP synthase V-type ATPase subunit E-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
HD-domain/PDEase-like Nucleotidyltransferase 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
PreATP-grasp domain Rudiment single hybrid motif 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
PDZ domain-like ClpP/crotonase 11
Ribonuclease H-like DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
RNase III domain-like dsRNA-binding domain-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Thioredoxin-like GST C-terminal domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Pentapeptide repeat-like Pentapeptide repeat-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Trigger factor ribosome-binding domain FKBP-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Nucleotidyltransferase TGS-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases FabD/lysophospholipase-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
CheC-like Surface presentation of antigens (SPOA) 11
GIY-YIG endonuclease RuvA domain 2-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
RuvA domain 2-like BRCT domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
PIN domain-like DNA/RNA polymerases 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Nucleic acid-binding proteins GAD domain-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
ABC transporter transmembrane region FabD/lysophospholipase-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
ACT-like ACT-like 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Phase 1 flagellin Phase 1 flagellin 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
ABC transporter transmembrane region Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Macro domain-like Zn-dependent exopeptidases 11
GroES-like NAD(P)-binding Rossmann-fold domains 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
TGS-like Class II aaRS ABD-related 11
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PLP-binding barrel Alanine racemase C-terminal domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Translation proteins Translation proteins 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Zinc beta-ribbon DNA primase core 11
TPR-like TPR-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Class II aaRS and biotin synthetases Translation proteins 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Nucleotide-binding domain Riboflavin synthase domain-like 11
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Cytochrome c Cytochrome c 11
Class II aaRS and biotin synthetases GAD domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Bacterial muramidases Lysozyme-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
ClpP/crotonase ClpP/crotonase 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11

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