All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
Actin-like ATPase domain | Actin-like ATPase domain | 6 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 5 | 5 | |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 5 | 2 | |
MurD-like peptide ligases, catalytic domain | MurD-like peptide ligases, peptide-binding domain | 5 | 3 | |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 5 | 4 | |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 5 | 2 | |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 4 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 4 | 4 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 3 | 3 | |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 3 | 3 | |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 3 | 3 | |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 3 | 3 | |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 3 | 2 | |
FKBP-like | Triger factor/SurA peptide-binding domain-like | 3 | 3 | |
Nucleotidylyl transferase | An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 3 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 3 | 3 | |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 2 | 2 | |
Trypsin-like serine proteases | PDZ domain-like | 2 | 2 | |
Sigma2 domain of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 2 | 2 | |
Nucleic acid-binding proteins | RuvA domain 2-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 2 | 1 | |
MurCD N-terminal domain | MurD-like peptide ligases, catalytic domain | 2 | 1 | |
CBS-domain pair | FAD-binding/transporter-associated domain-like | 2 | 2 | |
ThrRS/AlaRS common domain | Class II aaRS and biotin synthetases | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | "Winged helix" DNA-binding domain | 2 | 2 | |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 2 | 2 | |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 2 | 2 | |
Carbamate kinase-like | ACT-like | 2 | 2 | |
Alpha-L RNA-binding motif | Pseudouridine synthase | 2 | 1 | |
Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 2 | 2 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 2 | 1 | |
ValRS/IleRS/LeuRS editing domain | Nucleotidylyl transferase | 2 | 2 | |
CheY-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 | |
MurE/MurF N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 2 | 1 | |
Penicillin binding protein dimerisation domain | beta-lactamase/transpeptidase-like | 2 | 1 | |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 2 | 1 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 2 | 2 | |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 2 | 2 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 | |
Translation proteins | EF-G C-terminal domain-like | 2 | 2 | |
MurCD N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 2 | 1 | |
CheY-like | C-terminal effector domain of the bipartite response regulators | 2 | 1 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 2 | 2 | |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 2 | 2 | |
Homodimeric domain of signal transducing histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
Lysozyme-like | beta-lactamase/transpeptidase-like | 2 | 2 | |
tRNA-binding arm | Class II aaRS and biotin synthetases | 2 | 1 | |
CheY-like | Homeodomain-like | 2 | 1 | |
Translation proteins SH3-like domain | Nucleic acid-binding proteins | 2 | 2 | |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Homeodomain-like | 2 | 1 | |
MurE/MurF N-terminal domain | MurD-like peptide ligases, catalytic domain | 2 | 1 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 2 | 1 | |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 2 | 2 | |
FliG | FliG | 1 | 1 | |
PreATP-grasp domain | Single hybrid motif | 1 | 1 | |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 1 | 1 | |
Double Clp-N motif | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 1 | 1 | |
Formyltransferase | FMT C-terminal domain-like | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 1 | 1 | |
GroEL equatorial domain-like | GroEL apical domain-like | 1 | 1 | |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 1 | 1 | |
Nucleotidylyl transferase | Alpha-L RNA-binding motif | 1 | 1 | |
Thiolase-like | Thiolase-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Helical scaffold and wing domains of SecA | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
Translation proteins | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 1 | 1 | |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 1 | 1 | |
PUA domain-like | alpha/beta knot | 1 | 1 | |
Hypothetical protein SAV1430 | Fe-S cluster assembly (FSCA) domain-like | 1 | 1 | |
Phosphohistidine domain | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
Translation proteins | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 1 | 1 | |
Single hybrid motif | CoA-dependent acyltransferases | 1 | 1 | |
Glutamine synthetase/guanido kinase | GatB/YqeY motif | 1 | 1 | |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 1 | 1 | |
Nucleic acid-binding proteins | Rad51 N-terminal domain-like | 1 | 1 | |
2Fe-2S ferredoxin-like | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 | |
Class II aaRS and biotin synthetases | C-terminal domain of transcriptional repressors | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 1 | 1 | |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
TGS-like | ThrRS/AlaRS common domain | 1 | 1 | |
Rho N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
Peptidase/esterase 'gauge' domain | alpha/beta-Hydrolases | 1 | 1 | |
PheT/TilS domain | Putative DNA-binding domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 | |
RuvA domain 2-like | DNA helicase RuvA subunit, C-terminal domain | 1 | 1 | |
Nqo1 middle domain-like | Nqo1C-terminal domain-like | 1 | 1 | |
DnaK suppressor protein DksA, alpha-hairpin domain | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
Nqo1 FMN-binding domain-like | Nqo1 middle domain-like | 1 | 1 | |
Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 1 | 1 | |
PIN domain-like | Ribonuclease H-like | 1 | 1 | |
HAD-like | Calcium ATPase, transmembrane domain M | 1 | 1 | |
Flagellar hook protein flgE | Flagellar hook protein flgE | 1 | 1 | |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Nucleic acid-binding proteins | 1 | 1 | |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 1 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transduction domain A | 1 | 1 | |
DNA clamp | DNA clamp | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal UvrC-binding domain of UvrB | 1 | 1 | |
Calcium ATPase, transduction domain A | HAD-like | 1 | 1 | |
HMA, heavy metal-associated domain | HAD-like | 1 | 1 | |
beta-lactamase/transpeptidase-like | Penicillin-binding protein associated domain | 1 | 1 | |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 1 | 1 | |
Elongation factor Ts (EF-Ts), dimerisation domain | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 | |
PDZ domain-like | PDZ domain-like | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Trimeric LpxA-like enzymes | 1 | 1 | |
UBA-like | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 | |
Ribosomal protein L6 | Ribosomal protein L6 | 1 | 1 | |
Translation proteins | ThrRS/AlaRS common domain | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | RuvA domain 2-like | 1 | 1 | |
DNA repair protein MutS, domain II | DNA repair protein MutS, domain III | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Succinyl-CoA synthetase domains | 1 | 1 | |
DNA repair protein MutS, domain II | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 1 | 1 | |
Nucleotide-binding domain | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
TGS-like | Class II aaRS and biotin synthetases | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Phosphohistidine domain | 1 | 1 | |
S13-like H2TH domain | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
HD-domain/PDEase-like | TGS-like | 1 | 1 | |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TrpR-like | 1 | 1 | |
5' to 3' exonuclease, C-terminal subdomain | DNA/RNA polymerases | 1 | 1 | |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
4Fe-4S ferredoxins | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Aminoacid dehydrogenase-like, N-terminal domain | Isocitrate/Isopropylmalate dehydrogenase-like | 1 | 1 | |
Rudiment single hybrid motif | Single hybrid motif | 1 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | C-terminal domain of RNA polymerase alpha subunit | 1 | 1 | |
Carbon-nitrogen hydrolase | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
Nucleic acid-binding proteins | BRCT domain | 1 | 1 | |
ParB/Sulfiredoxin | KorB DNA-binding domain-like | 1 | 1 | |
N-terminal domain of MutM-like DNA repair proteins | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 1 | 1 | |
N-terminal domain of the delta subunit of the F1F0-ATP synthase | V-type ATPase subunit E-like | 1 | 1 | |
YhbC-like, N-terminal domain | YhbC-like, C-terminal domain | 1 | 1 | |
Pre-protein crosslinking domain of SecA | Helical scaffold and wing domains of SecA | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 1 | 1 | |
HD-domain/PDEase-like | Nucleotidyltransferase | 1 | 1 | |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 1 | 1 | |
PreATP-grasp domain | Rudiment single hybrid motif | 1 | 1 | |
N-utilization substance G protein NusG, N-terminal domain | Translation proteins SH3-like domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 1 | 1 | |
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain | Alkaline phosphatase-like | 1 | 1 | |
DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 1 | 1 | |
PDZ domain-like | ClpP/crotonase | 1 | 1 | |
Ribonuclease H-like | DNA/RNA polymerases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 1 | 1 | |
Mechanosensitive channel protein MscS (YggB), transmembrane region | Sm-like ribonucleoproteins | 1 | 1 | |
Transmembrane di-heme cytochromes | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) | 1 | 1 | |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 1 | 1 | |
Putative DNA-binding domain | Anticodon-binding domain of PheRS | 1 | 1 | |
RNase III domain-like | dsRNA-binding domain-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 1 | 1 | |
Thioredoxin-like | GST C-terminal domain-like | 1 | 1 | |
Ribonuclease PH domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Chaperone J-domain | HSC20 (HSCB), C-terminal oligomerisation domain | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | DNA mismatch repair protein MutL | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 1 | 1 | |
Pentapeptide repeat-like | Pentapeptide repeat-like | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain III | 1 | 1 | |
5' to 3' exonuclease, C-terminal subdomain | Ribonuclease H-like | 1 | 1 | |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 1 | 1 | |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Trigger factor ribosome-binding domain | FKBP-like | 1 | 1 | |
DNA repair protein MutS, domain I | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 1 | 1 | |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
Nucleotidyltransferase | TGS-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RecA protein, C-terminal domain | 1 | 1 | |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | FabD/lysophospholipase-like | 1 | 1 | |
Rho N-terminal domain-like | Nucleic acid-binding proteins | 1 | 1 | |
CheC-like | Surface presentation of antigens (SPOA) | 1 | 1 | |
GIY-YIG endonuclease | RuvA domain 2-like | 1 | 1 | |
Nucleic acid-binding proteins | Anticodon-binding domain of PheRS | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Rad51 N-terminal domain-like | 1 | 1 | |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 1 | 1 | |
"Winged helix" DNA-binding domain | PLP-dependent transferases | 1 | 1 | |
TolB, N-terminal domain | Tricorn protease N-terminal domain | 1 | 1 | |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain II | 1 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | RBP11-like subunits of RNA polymerase | 1 | 1 | |
HAMP domain-like | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 1 | 1 | |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 1 | 1 | |
RuvA domain 2-like | BRCT domain | 1 | 1 | |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | CoaB-like | 1 | 1 | |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 1 | 1 | |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | Nucleic acid-binding proteins | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 1 | 1 | |
Translation initiation factor IF3, N-terminal domain | Translation initiation factor IF3, C-terminal domain | 1 | 1 | |
PIN domain-like | DNA/RNA polymerases | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 1 | 1 | |
Nucleic acid-binding proteins | GAD domain-like | 1 | 1 | |
Ribonuclease PH domain 2-like | Ribonuclease PH domain 2-like | 1 | 1 | |
ABC transporter transmembrane region | FabD/lysophospholipase-like | 1 | 1 | |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 1 | 1 | |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 1 | 1 | |
CorA soluble domain-like | Magnesium transport protein CorA, transmembrane region | 1 | 1 | |
PheT/TilS domain | Anticodon-binding domain of PheRS | 1 | 1 | |
ACT-like | ACT-like | 1 | 1 | |
DNA repair protein MutS, domain III | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Phase 1 flagellin | Phase 1 flagellin | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
Prokaryotic type I DNA topoisomerase | Zinc beta-ribbon | 1 | 1 | |
HAMP domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Isocitrate/Isopropylmalate dehydrogenase-like | 1 | 1 | |
ABC transporter transmembrane region | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | 1 | |
Macro domain-like | Zn-dependent exopeptidases | 1 | 1 | |
GroES-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 1 | 1 | |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
TGS-like | Class II aaRS ABD-related | 1 | 1 | |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Pre-protein crosslinking domain of SecA | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 1 | 1 | |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 1 | 1 | |
Trigger factor ribosome-binding domain | Triger factor/SurA peptide-binding domain-like | 1 | 1 | |
Nucleic acid-binding proteins | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
GreA transcript cleavage protein, N-terminal domain | FKBP-like | 1 | 1 | |
Translation proteins | Translation proteins | 1 | 1 | |
GIY-YIG endonuclease | C-terminal UvrC-binding domain of UvrB | 1 | 1 | |
N-terminal domain of DnaB helicase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 1 | 1 | |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Rad51 N-terminal domain-like | 1 | 1 | |
Nucleic acid-binding proteins | DNA helicase RuvA subunit, C-terminal domain | 1 | 1 | |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
Nqo1 FMN-binding domain-like | Nqo1C-terminal domain-like | 1 | 1 | |
Zinc beta-ribbon | DNA primase core | 1 | 1 | |
TPR-like | TPR-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
Type II DNA topoisomerase | GyrA/ParC C-terminal domain-like | 1 | 1 | |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | 1 | |
Obg GTP-binding protein N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FAD-binding/transporter-associated domain-like | Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain | 1 | 1 | |
Class II aaRS and biotin synthetases | Translation proteins | 1 | 1 | |
N-acetylmuramoyl-L-alanine amidase-like | PGBD-like | 1 | 1 | |
Nucleic acid-binding proteins | PheT/TilS domain | 1 | 1 | |
Ribosomal protein S5 domain 2-like | DNA mismatch repair protein MutL | 1 | 1 | |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 1 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transmembrane domain M | 1 | 1 | |
C-terminal UvrC-binding domain of UvrB | RuvA domain 2-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
2Fe-2S ferredoxin-like | 4Fe-4S ferredoxins | 1 | 1 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
Nucleotide-binding domain | Riboflavin synthase domain-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 1 | 1 | |
N-terminal domain of MutM-like DNA repair proteins | S13-like H2TH domain | 1 | 1 | |
Cytochrome c | Cytochrome c | 1 | 1 | |
Class II aaRS and biotin synthetases | GAD domain-like | 1 | 1 | |
RBP11-like subunits of RNA polymerase | C-terminal domain of RNA polymerase alpha subunit | 1 | 1 | |
Bacterial muramidases | Lysozyme-like | 1 | 1 | |
Nucleic acid-binding proteins | Putative DNA-binding domain | 1 | 1 | |
PUA domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 1 | 1 | |
L9 N-domain-like | Ribosomal protein L9 C-domain | 1 | 1 | |
Ribonuclease PH domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
ClpP/crotonase | ClpP/crotonase | 1 | 1 | |
PheT/TilS domain | Class II aaRS and biotin synthetases | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Putative methyltransferase TM0872, insert domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |