All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
Glucocorticoid receptor-like (DNA-binding domain) | Nuclear receptor ligand-binding domain | 272 | 22 | |
DNA/RNA polymerases | Ribonuclease H-like | 148 | 29 | |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 139 | 42 | |
Nicotinic receptor ligand binding domain-like | Neurotransmitter-gated ion-channel transmembrane pore | 97 | 11 | |
beta-beta-alpha zinc fingers | beta-beta-alpha zinc fingers | 96 | 23 | |
C-type lectin-like | C-type lectin-like | 92 | 19 | |
TRAF domain-like | POZ domain | 74 | 11 | |
Acid proteases | DNA/RNA polymerases | 65 | 18 | |
Voltage-gated potassium channels | Voltage-gated potassium channels | 56 | 10 | |
Immunoglobulin | Immunoglobulin | 56 | 41 | |
L domain-like | L domain-like | 55 | 23 | |
Acid proteases | Ribonuclease H-like | 54 | 13 | |
Retrovirus zinc finger-like domains | Acid proteases | 47 | 10 | |
Thioredoxin-like | GST C-terminal domain-like | 46 | 3 | |
SH2 domain | Protein kinase-like (PK-like) | 46 | 8 | |
Homeodomain-like | Homeodomain-like | 45 | 14 | |
Actin-like ATPase domain | Actin-like ATPase domain | 44 | 10 | |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 43 | 8 | |
EGF/Laminin | EGF/Laminin | 42 | 35 | |
RNA-binding domain, RBD | RNA-binding domain, RBD | 41 | 20 | |
C-type lectin-like | Spermadhesin, CUB domain | 39 | 8 | |
Glucocorticoid receptor-like (DNA-binding domain) | Glucocorticoid receptor-like (DNA-binding domain) | 39 | 25 | |
vWA-like | C-type lectin-like | 37 | 8 | |
RING/U-box | RING/U-box | 36 | 15 | |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 35 | 7 | |
POZ domain | Skp1 dimerisation domain-like | 34 | 4 | |
PAZ domain | Ribonuclease H-like | 34 | 5 | |
Family A G protein-coupled receptor-like | Family A G protein-coupled receptor-like | 34 | 13 | |
Ribonuclease H-like | Chromo domain-like | 33 | 4 | |
E set domains | E set domains | 32 | 11 | |
Retrovirus zinc finger-like domains | DNA/RNA polymerases | 30 | 9 | |
lambda repressor-like DNA-binding domains | lambda repressor-like DNA-binding domains | 30 | 10 | |
Multidrug efflux transporter AcrB transmembrane domain | Multidrug efflux transporter AcrB transmembrane domain | 30 | 5 | |
Protein kinase-like (PK-like) | Nucleotide cyclase | 29 | 11 | |
Periplasmic binding protein-like I | Protein kinase-like (PK-like) | 29 | 12 | |
DNase I-like | DNA/RNA polymerases | 28 | 5 | |
TPR-like | TPR-like | 27 | 14 | |
lambda repressor-like DNA-binding domains | Homeodomain-like | 26 | 5 | |
ARM repeat | ARM repeat | 26 | 16 | |
Periplasmic binding protein-like I | Nucleotide cyclase | 26 | 9 | |
Calcium ATPase, transmembrane domain M | HAD-like | 25 | 10 | |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 25 | 13 | |
Retrovirus zinc finger-like domains | Ribonuclease H-like | 25 | 6 | |
Fibronectin type III | Fibronectin type III | 25 | 22 | |
POZ domain | POZ domain | 25 | 15 | |
ABC transporter transmembrane region | ABC transporter transmembrane region | 25 | 6 | |
Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | 25 | 18 | |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 24 | 6 | |
Immunoglobulin | Fibronectin type III | 24 | 23 | |
BPTI-like | BPTI-like | 24 | 17 | |
Calcium ATPase, transmembrane domain M | Metal cation-transporting ATPase, ATP-binding domain N | 23 | 8 | |
Cyclin-like | Cyclin-like | 23 | 7 | |
Transducin (alpha subunit), insertion domain | P-loop containing nucleoside triphosphate hydrolases | 23 | 1 | |
Ankyrin repeat | Ankyrin repeat | 21 | 15 | |
Nucleotidyltransferase | PAP/OAS1 substrate-binding domain | 21 | 8 | |
Eukaryotic type KH-domain (KH-domain type I) | Eukaryotic type KH-domain (KH-domain type I) | 21 | 11 | |
HAD-like | Metal cation-transporting ATPase, ATP-binding domain N | 21 | 7 | |
LDL receptor-like module | LDL receptor-like module | 20 | 19 | |
Ypt/Rab-GAP domain of gyp1p | Ypt/Rab-GAP domain of gyp1p | 20 | 11 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | C2 domain (Calcium/lipid-binding domain, CaLB) | 19 | 12 | |
Calcium ATPase, transduction domain A | Metal cation-transporting ATPase, ATP-binding domain N | 19 | 5 | |
PDZ domain-like | PDZ domain-like | 18 | 12 | |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 18 | 5 | |
Ankyrin repeat | BRCT domain | 18 | 6 | |
Metalloproteases ("zincins"), catalytic domain | Spermadhesin, CUB domain | 17 | 7 | |
Second domain of FERM | PH domain-like | 17 | 11 | |
Growth factor receptor domain | EGF/Laminin | 17 | 17 | |
Calcium ATPase, transduction domain A | HAD-like | 17 | 4 | |
EF-hand | EF-hand | 17 | 12 | |
vWA-like | vWA-like | 17 | 13 | |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 17 | 11 | |
Leukotriene A4 hydrolase N-terminal domain | Metalloproteases ("zincins"), catalytic domain | 17 | 5 | |
Spermadhesin, CUB domain | Spermadhesin, CUB domain | 17 | 12 | |
DBL homology domain (DH-domain) | PH domain-like | 17 | 12 | |
WD40 repeat-like | WD40 repeat-like | 16 | 8 | |
Ubiquitin-like | Second domain of FERM | 16 | 10 | |
Ubiquitin-like | PH domain-like | 16 | 10 | |
Cysteine proteinases | DNA/RNA polymerases | 16 | 5 | |
GroES-like | NAD(P)-binding Rossmann-fold domains | 16 | 4 | |
Cysteine-rich domain | Cysteine-rich domain | 15 | 11 | |
Cadherin-like | Cadherin-like | 15 | 14 | |
Thioredoxin-like | Thioredoxin-like | 14 | 7 | |
Viral glycoprotein ectodomain-like | Acid proteases | 14 | 7 | |
Protein kinase-like (PK-like) | Protein kinase-like (PK-like) | 14 | 10 | |
Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 14 | 2 | |
Viral glycoprotein ectodomain-like | DNA/RNA polymerases | 14 | 7 | |
FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 14 | 5 | |
(Trans)glycosidases | Glycosyl hydrolase domain | 14 | 8 | |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 13 | 6 | |
Translation proteins | EF-G C-terminal domain-like | 13 | 7 | |
Hairpin loop containing domain-like | Hairpin loop containing domain-like | 13 | 10 | |
CoA-dependent acyltransferases | CoA-dependent acyltransferases | 13 | 4 | |
Spectrin repeat | Spectrin repeat | 13 | 13 | |
FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 13 | 4 | |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 13 | 10 | |
TSP-1 type 1 repeat | TSP-1 type 1 repeat | 13 | 13 | |
SH3-domain | SH3-domain | 13 | 12 | |
SH3-domain | SH2 domain | 12 | 8 | |
HMG-box | HMG-box | 12 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 12 | 6 | |
Growth factor receptor domain | Growth factor receptor domain | 12 | 12 | |
RING/U-box | B-box zinc-binding domain | 12 | 10 | |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 12 | 6 | |
ARM repeat | Protein kinase-like (PK-like) | 12 | 12 | |
POZ domain | Voltage-gated potassium channels | 12 | 2 | |
Viral glycoprotein ectodomain-like | Ribonuclease H-like | 12 | 5 | |
(Phosphotyrosine protein) phosphatases II | (Phosphotyrosine protein) phosphatases II | 12 | 8 | |
(Trans)glycosidases | Chitinase insertion domain | 11 | 5 | |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 11 | 5 | |
Translation proteins | Ribosomal protein S5 domain 2-like | 11 | 5 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 11 | 4 | |
Serine protease inhibitors | Serine protease inhibitors | 11 | 7 | |
Retrovirus zinc finger-like domains | Retrovirus zinc finger-like domains | 11 | 6 | |
WD40 repeat-like | Protein kinase-like (PK-like) | 11 | 6 | |
SH3-domain | P-loop containing nucleoside triphosphate hydrolases | 11 | 9 | |
Thioesterase/thiol ester dehydrase-isomerase | Thioesterase/thiol ester dehydrase-isomerase | 11 | 2 | |
Cysteine-rich domain | Protein kinase-like (PK-like) | 11 | 9 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 11 | 4 | |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 11 | 4 | |
Intermediate filament protein, coiled coil region | Intermediate filament protein, coiled coil region | 11 | 8 | |
Ubiquitin-like | Ubiquitin-like | 10 | 7 | |
GroEL equatorial domain-like | GroEL-intermediate domain like | 10 | 1 | |
SH3-domain | Protein kinase-like (PK-like) | 10 | 7 | |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 10 | 4 | |
Bactericidal permeability-increasing protein, BPI | Bactericidal permeability-increasing protein, BPI | 10 | 6 | |
CCCH zinc finger | CCCH zinc finger | 10 | 2 | |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 10 | 4 | |
GroEL equatorial domain-like | GroEL apical domain-like | 10 | 1 | |
GroEL-intermediate domain like | GroEL apical domain-like | 10 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 9 | 8 | |
Invertebrate chitin-binding proteins | Invertebrate chitin-binding proteins | 9 | 9 | |
Acyl-CoA dehydrogenase C-terminal domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 9 | 3 | |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 9 | 4 | |
Voltage-gated potassium channels | cAMP-binding domain-like | 9 | 3 | |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 9 | 4 | |
Nucleotide-diphospho-sugar transferases | Ricin B-like lectins | 9 | 5 | |
Glucocorticoid receptor-like (DNA-binding domain) | Homeodomain-like | 9 | 7 | |
EGF/Laminin | Concanavalin A-like lectins/glucanases | 9 | 9 | |
Intermediate filament protein, coiled coil region | Lamin A/C globular tail domain | 9 | 7 | |
BRCT domain | BRCT domain | 9 | 7 | |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 9 | 4 | |
Purple acid phosphatase, N-terminal domain | Metallo-dependent phosphatases | 9 | 2 | |
Cullin repeat-like | Cullin homology domain | 8 | 3 | |
MFPT repeat-like | MFPT repeat-like | 8 | 1 | |
PH domain-like | PH domain-like | 8 | 8 | |
Protease propeptides/inhibitors | Zn-dependent exopeptidases | 8 | 2 | |
alpha/beta-Hydrolases | alpha/beta-Hydrolases | 8 | 6 | |
P-loop containing nucleoside triphosphate hydrolases | PDZ domain-like | 8 | 6 | |
Myosin rod fragments | Myosin rod fragments | 8 | 7 | |
PH domain-like | FYVE/PHD zinc finger | 8 | 7 | |
Ligand-binding domain in the NO signalling and Golgi transport | Nucleotide cyclase | 8 | 2 | |
SH3-domain | BAR/IMD domain-like | 8 | 4 | |
ValRS/IleRS/LeuRS editing domain | Nucleotidylyl transferase | 8 | 5 | |
CRAL/TRIO N-terminal domain | CRAL/TRIO domain | 8 | 4 | |
PH domain-like | SH3-domain | 8 | 8 | |
LDL receptor-like module | EGF/Laminin | 8 | 8 | |
Metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 8 | 6 | |
Glutamine synthetase, N-terminal domain | Glutamine synthetase/guanido kinase | 8 | 2 | |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 8 | 7 | |
RNI-like | ARM repeat | 8 | 4 | |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 8 | 7 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Protein kinase-like (PK-like) | 7 | 6 | |
Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 7 | 4 | |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 7 | 3 | |
"Winged helix" DNA-binding domain | P-loop containing nucleoside triphosphate hydrolases | 7 | 7 | |
Metalloproteases ("zincins"), catalytic domain | TSP-1 type 1 repeat | 7 | 6 | |
Nuclear receptor ligand-binding domain | Nuclear receptor ligand-binding domain | 7 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | Myosin rod fragments | 7 | 6 | |
Thiolase-like | Thiolase-like | 7 | 2 | |
Periplasmic binding protein-like I | Periplasmic binding protein-like II | 7 | 5 | |
Cullin repeat-like | "Winged helix" DNA-binding domain | 7 | 2 | |
Domain of poly(ADP-ribose) polymerase | ADP-ribosylation | 7 | 6 | |
CRAL/TRIO domain | Supernatant protein factor (SPF), C-terminal domain | 7 | 3 | |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 7 | 6 | |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 7 | 5 | |
FYVE/PHD zinc finger | SET domain | 7 | 6 | |
WW domain | WW domain | 7 | 7 | |
FYVE/PHD zinc finger | FYVE/PHD zinc finger | 7 | 7 | |
Lipovitellin-phosvitin complex; beta-sheet shell regions | Lipovitellin-phosvitin complex, superhelical domain | 7 | 3 | |
"Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 7 | 7 | |
Tudor/PWWP/MBT | Tudor/PWWP/MBT | 7 | 5 | |
beta-beta-alpha zinc fingers | Ribonuclease H-like | 7 | 2 | |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 7 | 4 | |
Cullin homology domain | "Winged helix" DNA-binding domain | 7 | 2 | |
Rudiment single hybrid motif | Single hybrid motif | 7 | 6 | |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 7 | 1 | |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 7 | 4 | |
Chromo domain-like | Chromo domain-like | 7 | 6 | |
DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 7 | 2 | |
2Fe-2S ferredoxin-like | FAD-binding/transporter-associated domain-like | 6 | 3 | |
Fibronectin type III | Protein kinase-like (PK-like) | 6 | 6 | |
P-loop containing nucleoside triphosphate hydrolases | PH domain-like | 6 | 4 | |
Cysteine-rich domain | PH domain-like | 6 | 6 | |
PreATP-grasp domain | Rudiment single hybrid motif | 6 | 5 | |
Arp2/3 complex subunits | Arp2/3 complex subunits | 6 | 4 | |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 6 | 3 | |
Lipovitellin-phosvitin complex; beta-sheet shell regions | Lipovitellin-phosvitin complex; beta-sheet shell regions | 6 | 2 | |
Actin depolymerizing proteins | Actin depolymerizing proteins | 6 | 4 | |
2Fe-2S ferredoxin-like | Molybdenum cofactor-binding domain | 6 | 3 | |
FAD-binding/transporter-associated domain-like | CO dehydrogenase molybdoprotein N-domain-like | 6 | 3 | |
PH domain-like | Protein kinase-like (PK-like) | 6 | 6 | |
PH domain-like | PDZ domain-like | 6 | 6 | |
EF-hand | PLC-like phosphodiesterases | 6 | 6 | |
SET domain | SET domain | 6 | 5 | |
Ribonuclease H-like | Restriction endonuclease-like | 6 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Smc hinge domain | 6 | 5 | |
PDZ domain-like | SH3-domain | 6 | 4 | |
Cysteine proteinases | Calpain large subunit, middle domain (domain III) | 6 | 4 | |
YWTD domain | EGF/Laminin | 6 | 6 | |
Phospholipase D/nuclease | Phospholipase D/nuclease | 6 | 4 | |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 6 | 5 | |
PurM N-terminal domain-like | PurM C-terminal domain-like | 6 | 5 | |
CO dehydrogenase molybdoprotein N-domain-like | Molybdenum cofactor-binding domain | 6 | 3 | |
SH3-domain | DBL homology domain (DH-domain) | 6 | 6 | |
PH domain-like | SH2 domain | 6 | 5 | |
2Fe-2S ferredoxin-like | CO dehydrogenase molybdoprotein N-domain-like | 6 | 3 | |
Galactose mutarotase-like | (Trans)glycosidases | 6 | 1 | |
PH domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 6 | 5 | |
Galactose mutarotase-like | Glycosyl hydrolase domain | 6 | 1 | |
Immunoglobulin | Protein kinase-like (PK-like) | 6 | 5 | |
Acid proteases | Acid proteases | 6 | 5 | |
FKBP-like | FKBP-like | 6 | 4 | |
RING/U-box | P-loop containing nucleoside triphosphate hydrolases | 6 | 4 | |
Clc chloride channel | CBS-domain pair | 6 | 2 | |
FAD-binding/transporter-associated domain-like | Molybdenum cofactor-binding domain | 6 | 3 | |
PapD-like | RING/U-box | 5 | 4 | |
CO dehydrogenase ISP C-domain like | FAD-binding/transporter-associated domain-like | 5 | 2 | |
Ubiquitin-like | UBA-like | 5 | 3 | |
CRAL/TRIO N-terminal domain | Supernatant protein factor (SPF), C-terminal domain | 5 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | Acyl-CoA N-acyltransferases (Nat) | 5 | 3 | |
Cdc48 domain 2-like | P-loop containing nucleoside triphosphate hydrolases | 5 | 3 | |
BRK domain-like | P-loop containing nucleoside triphosphate hydrolases | 5 | 3 | |
SMAD MH1 domain | SMAD/FHA domain | 5 | 2 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 5 | 2 | |
EGF/Laminin | vWA-like | 5 | 5 | |
Ribonuclease H-like | Ribonuclease H-like | 5 | 5 | |
Saposin | Saposin | 5 | 4 | |
PGBD-like | Metalloproteases ("zincins"), catalytic domain | 5 | 4 | |
L domain-like | Immunoglobulin | 5 | 4 | |
DNA/RNA polymerases | DNA breaking-rejoining enzymes | 5 | 4 | |
EF-hand | PH domain-like | 5 | 5 | |
CBS-domain pair | CBS-domain pair | 5 | 3 | |
PreATP-grasp domain | Single hybrid motif | 5 | 4 | |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 5 | 3 | |
WGR domain-like | Domain of poly(ADP-ribose) polymerase | 5 | 4 | |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 5 | 3 | |
L domain-like | Family A G protein-coupled receptor-like | 5 | 5 | |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 5 | 4 | |
Ankyrin repeat | P-loop containing nucleoside triphosphate hydrolases | 5 | 5 | |
WGR domain-like | ADP-ribosylation | 5 | 4 | |
YWTD domain | LDL receptor-like module | 5 | 5 | |
Cadherin-like | Concanavalin A-like lectins/glucanases | 5 | 5 | |
dsRNA-binding domain-like | dsRNA-binding domain-like | 5 | 4 | |
2Fe-2S ferredoxin-like | CO dehydrogenase ISP C-domain like | 5 | 2 | |
TRAF domain-like | TRAF domain-like | 5 | 4 | |
WWE domain | RING/U-box | 5 | 3 | |
CO dehydrogenase ISP C-domain like | CO dehydrogenase molybdoprotein N-domain-like | 5 | 2 | |
(Trans)glycosidases | (Trans)glycosidases | 5 | 4 | |
Ankyrin repeat | FabD/lysophospholipase-like | 5 | 2 | |
RNA-binding domain, RBD | NTF2-like | 5 | 4 | |
GTPase activation domain, GAP | PH domain-like | 5 | 5 | |
FYVE/PHD zinc finger | Clavaminate synthase-like | 5 | 4 | |
CO dehydrogenase ISP C-domain like | Molybdenum cofactor-binding domain | 5 | 2 | |
RNI-like | RNI-like | 5 | 3 | |
Complement control module/SCR domain | Complement control module/SCR domain | 5 | 5 | |
PYP-like sensor domain (PAS domain) | PYP-like sensor domain (PAS domain) | 5 | 4 | |
PLC-like phosphodiesterases | C2 domain (Calcium/lipid-binding domain, CaLB) | 5 | 5 | |
Ubiquitin-like | PDZ domain-like | 5 | 5 | |
Restriction endonuclease-like | DNA/RNA polymerases | 5 | 1 | |
SNARE-like | Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 5 | 2 | |
Metalloproteases ("zincins"), catalytic domain | Metalloproteases ("zincins"), catalytic domain | 5 | 4 | |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 5 | 2 | |
PH domain-like | PLC-like phosphodiesterases | 5 | 5 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Cysteine-rich domain | 5 | 4 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 5 | 4 | |
cAMP-binding domain-like | cAMP-binding domain-like | 5 | 5 | |
Calponin-homology domain, CH-domain | Spectrin repeat | 5 | 5 | |
EGF/Laminin | Immunoglobulin | 5 | 4 | |
"Winged helix" DNA-binding domain | Periplasmic binding protein-like II | 5 | 1 | |
ARM repeat | Formin homology 2 domain (FH2 domain) | 5 | 5 | |
Galactose-binding domain-like | EGF/Laminin | 5 | 4 | |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 5 | 2 | |
C-type lectin-like | LDL receptor-like module | 4 | 3 | |
Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 4 | 2 | |
vWA-like | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 2 | |
Folate-binding domain | Aminomethyltransferase beta-barrel domain | 4 | 3 | |
Indigoidine synthase A-like | Ribokinase-like | 4 | 2 | |
Pectin lyase-like | Pectin lyase-like | 4 | 4 | |
Cysteine-rich domain | NAD kinase/diacylglycerol kinase-like | 4 | 4 | |
TrpR-like | Homeodomain-like | 4 | 3 | |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 4 | 2 | |
EF-hand | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 4 | |
alpha-catenin/vinculin-like | alpha-catenin/vinculin-like | 4 | 4 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 4 | 3 | |
HIT/MYND zinc finger-like | SET domain | 4 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 4 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 4 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Blood coagulation inhibitor (disintegrin) | 4 | 1 | |
SAM/Pointed domain | SAM/Pointed domain | 4 | 4 | |
Zn-finger domain of Sec23/24 | Helical domain of Sec23/24 | 4 | 2 | |
NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 4 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | Bromodomain | 4 | 2 | |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 4 | 1 | |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 4 | 3 | |
Eukaryotic type KH-domain (KH-domain type I) | Nucleic acid-binding proteins | 4 | 3 | |
beta-sandwich domain of Sec23/24 | Helical domain of Sec23/24 | 4 | 2 | |
ADC-like | Cdc48 domain 2-like | 4 | 2 | |
Ubiquitin-like | Protein kinase-like (PK-like) | 4 | 4 | |
Flavoproteins | Ferredoxin reductase-like, C-terminal NADP-linked domain | 4 | 3 | |
PEP carboxykinase N-terminal domain | PEP carboxykinase-like | 4 | 2 | |
ClpP/crotonase | ClpP/crotonase | 4 | 4 | |
Nucleotide-binding domain | FAD-linked reductases, C-terminal domain | 4 | 2 | |
Nicotinic receptor ligand binding domain-like | Nicotinic receptor ligand binding domain-like | 4 | 4 | |
Sema domain | Plexin repeat | 4 | 3 | |
Macro domain-like | P-loop containing nucleoside triphosphate hydrolases | 4 | 3 | |
Nucleotidylyl transferase | Nucleotidylyl transferase | 4 | 2 | |
PH domain-like | (Phosphotyrosine protein) phosphatases II | 4 | 4 | |
Rhodanese/Cell cycle control phosphatase | Rhodanese/Cell cycle control phosphatase | 4 | 2 | |
Flavoproteins | Riboflavin synthase domain-like | 4 | 3 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 4 | 3 | |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 4 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Ribonuclease H-like | 4 | 4 | |
PDZ domain-like | "Winged helix" DNA-binding domain | 4 | 4 | |
Cysteine-rich domain | GTPase activation domain, GAP | 4 | 4 | |
FYVE/PHD zinc finger | Bromodomain | 4 | 4 | |
SH2 domain | SH2 domain | 4 | 4 | |
DNA/RNA polymerases | Lesion bypass DNA polymerase (Y-family), little finger domain | 4 | 2 | |
Voltage-gated potassium channels | Periplasmic binding protein-like II | 4 | 4 | |
ARM repeat | Clathrin adaptor appendage domain | 4 | 3 | |
PR-1-like | PR-1-like | 4 | 4 | |
S15/NS1 RNA-binding domain | Class II aaRS and biotin synthetases | 4 | 3 | |
Helical domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 2 | |
beta-sandwich domain of Sec23/24 | vWA-like | 4 | 2 | |
Thyroglobulin type-1 domain | BPTI-like | 4 | 3 | |
MOSC N-terminal domain-like | PK beta-barrel domain-like | 4 | 2 | |
DNA repair protein MutS, domain III | P-loop containing nucleoside triphosphate hydrolases | 4 | 4 | |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 4 | 4 | |
Fibronectin type III | (Phosphotyrosine protein) phosphatases II | 4 | 4 | |
Tropomyosin | P-loop containing nucleoside triphosphate hydrolases | 4 | 4 | |
DBL homology domain (DH-domain) | FYVE/PHD zinc finger | 4 | 3 | |
Heme-dependent peroxidases | Heme-dependent peroxidases | 4 | 3 | |
Chromo domain-like | SET domain | 4 | 2 | |
Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 4 | 4 | |
Zn-finger domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 2 | |
beta-sandwich domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 2 | |
L domain-like | NTF2-like | 4 | 3 | |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 4 | 3 | |
vWA-like | Helical domain of Sec23/24 | 4 | 2 | |
Sec7 domain | PH domain-like | 4 | 1 | |
Subtilisin-like | Galactose-binding domain-like | 4 | 4 | |
S-adenosyl-L-methionine-dependent methyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 4 | 3 | |
beta-sandwich domain of Sec23/24 | Zn-finger domain of Sec23/24 | 4 | 2 | |
Bromodomain | Bromodomain | 4 | 4 | |
Protein kinase-like (PK-like) | Ankyrin repeat | 4 | 4 | |
S15/NS1 RNA-binding domain | Class II aaRS ABD-related | 4 | 3 | |
Protein kinase-like (PK-like) | KA1-like | 4 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Chromo domain-like | 4 | 4 | |
Ankyrin repeat | SAM/Pointed domain | 4 | 4 | |
Succinyl-CoA synthetase domains | NAD(P)-binding Rossmann-fold domains | 4 | 2 | |
RING/U-box | NHL repeat | 4 | 4 | |
Growth factor receptor domain | LDL receptor-like module | 4 | 4 | |
Spectrin repeat | EF-hand | 4 | 4 | |
PDZ domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 3 | |
L domain-like | Protein kinase-like (PK-like) | 4 | 4 | |
Apolipoprotein A-I | Apolipoprotein A-I | 4 | 4 | |
Nucleotide cyclase | Nucleotide cyclase | 4 | 2 | |
POZ domain | Kelch motif | 4 | 3 | |
Nucleotidyltransferase | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 4 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Cysteine proteinases | 4 | 3 | |
ADC-like | P-loop containing nucleoside triphosphate hydrolases | 4 | 2 | |
Cysteine proteinases | Cysteine proteinases | 4 | 3 | |
Single hybrid motif | CoA-dependent acyltransferases | 4 | 3 | |
Fibronectin type III | ARM repeat | 4 | 3 | |
PAP/OAS1 substrate-binding domain | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 4 | 2 | |
Galactose-binding domain-like | (Trans)glycosidases | 4 | 3 | |
Translation proteins SH3-like domain | Nucleic acid-binding proteins | 4 | 2 | |
Neurotransmitter-gated ion-channel transmembrane pore | Neurotransmitter-gated ion-channel transmembrane pore | 4 | 4 | |
Zn-finger domain of Sec23/24 | vWA-like | 4 | 2 | |
Voltage-gated potassium channels | Small-conductance potassium channel | 4 | 1 | |
BAR/IMD domain-like | GTPase activation domain, GAP | 4 | 4 | |
Ubiquitin-like | Cysteine-rich domain | 4 | 4 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | vWA-like | 3 | 2 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | HRDC-like | 3 | 3 | |
PH domain-like | Ankyrin repeat | 3 | 3 | |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 3 | 2 | |
F-box domain | F-box domain | 3 | 2 | |
Spermadhesin, CUB domain | EGF/Laminin | 3 | 3 | |
Growth factor receptor domain | Concanavalin A-like lectins/glucanases | 3 | 3 | |
EF-hand | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
Glycoside hydrolase/deacetylase | Galactose mutarotase-like | 3 | 2 | |
CalX-like | CalX-like | 3 | 1 | |
Retrovirus zinc finger-like domains | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
Metalloproteases ("zincins"), catalytic domain | Hemopexin-like domain | 3 | 3 | |
Guanido kinase N-terminal domain | Glutamine synthetase/guanido kinase | 3 | 2 | |
ThrRS/AlaRS common domain | Class II aaRS and biotin synthetases | 3 | 2 | |
Kazal-type serine protease inhibitors | Kazal-type serine protease inhibitors | 3 | 3 | |
Periplasmic binding protein-like I | Periplasmic binding protein-like I | 3 | 2 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 | |
"Winged helix" DNA-binding domain | E2F-DP heterodimerization region | 3 | 3 | |
PapD-like | PapD-like | 3 | 3 | |
Ubiquitin-like | Ras GEF | 3 | 3 | |
SRCR-like | C-type lectin-like | 3 | 2 | |
Galactose-binding domain-like | Protein kinase-like (PK-like) | 3 | 2 | |
Glucocorticoid receptor-like (DNA-binding domain) | Domain of poly(ADP-ribose) polymerase | 3 | 2 | |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 3 | 2 | |
Ankyrin repeat | DEATH domain | 3 | 3 | |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 3 | 3 | |
Nucleotidylyl transferase | Ribosomal protein L25-like | 3 | 3 | |
DEATH domain | Caspase-like | 3 | 2 | |
Hairpin loop containing domain-like | C-type lectin-like | 3 | 2 | |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 3 | 1 | |
Homeodomain-like | FAD/NAD(P)-binding domain | 3 | 2 | |
BRK domain-like | Bromodomain | 3 | 1 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 3 | 2 | |
RING/U-box | UBA-like | 3 | 2 | |
RING/U-box | Cysteine proteinases | 3 | 3 | |
SH3-domain | Fibronectin type III | 3 | 3 | |
MFS general substrate transporter | Kazal-type serine protease inhibitors | 3 | 1 | |
Galactose-binding domain-like | Growth factor receptor domain | 3 | 3 | |
PDZ domain-like | SAM/Pointed domain | 3 | 3 | |
Growth factor receptor domain | Protein kinase-like (PK-like) | 3 | 3 | |
Ribosomal L27 protein-like | Nucleic acid-binding proteins | 3 | 2 | |
Spectrin repeat | PH domain-like | 3 | 3 | |
Sec63 N-terminal domain-like | E set domains | 3 | 3 | |
Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 3 | 2 | |
RuvA domain 2-like | Nucleic acid-binding proteins | 3 | 3 | |
NagB/RpiA/CoA transferase-like | NagB/RpiA/CoA transferase-like | 3 | 2 | |
WW domain | Hect, E3 ligase catalytic domain | 3 | 3 | |
Quinoprotein alcohol dehydrogenase-like | WD40 repeat-like | 3 | 3 | |
Spermadhesin, CUB domain | TSP-1 type 1 repeat | 3 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 3 | 2 | |
EF-hand | SH3-domain | 3 | 3 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 3 | 3 | |
"Winged helix" DNA-binding domain | Sec63 N-terminal domain-like | 3 | 3 | |
F-box domain | WD40 repeat-like | 3 | 3 | |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 3 | 3 | |
Spectrin repeat | SH3-domain | 3 | 3 | |
ARM repeat | WD40 repeat-like | 3 | 2 | |
Arp2/3 complex subunits | HIT/MYND zinc finger-like | 3 | 3 | |
beta-lactamase/transpeptidase-like | Ankyrin repeat | 3 | 2 | |
Transcription factor IIA (TFIIA), alpha-helical domain | Transcription factor IIA (TFIIA), beta-barrel domain | 3 | 2 | |
Ankyrin repeat | SH3-domain | 3 | 3 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | ARM repeat | 3 | 3 | |
Leukotriene A4 hydrolase N-terminal domain | ARM repeat | 3 | 1 | |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 3 | 2 | |
Zinc beta-ribbon | Cyclin-like | 3 | 2 | |
F1F0 ATP synthase subunit C | F1F0 ATP synthase subunit C | 3 | 2 | |
PH domain-like | Ypt/Rab-GAP domain of gyp1p | 3 | 3 | |
ARM repeat | "Winged helix" DNA-binding domain | 3 | 2 | |
Hermes dimerisation domain | Ribonuclease H-like | 3 | 2 | |
HCP-like | TPR-like | 3 | 3 | |
RING/U-box | TRAF domain-like | 3 | 2 | |
Protein kinase-like (PK-like) | DEATH domain | 3 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | dsRNA-binding domain-like | 3 | 2 | |
RNA-binding domain, RBD | L domain-like | 3 | 2 | |
SNARE fusion complex | SNARE fusion complex | 3 | 3 | |
Calponin-homology domain, CH-domain | E set domains | 3 | 3 | |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 3 | 2 | |
EF-hand | Mitochondrial carrier | 3 | 2 | |
Calponin-homology domain, CH-domain | PH domain-like | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Sec63 N-terminal domain-like | 3 | 3 | |
ArfGap/RecO-like zinc finger | Ankyrin repeat | 3 | 3 | |
Families 57/38 glycoside transferase middle domain | Galactose mutarotase-like | 3 | 2 | |
Thyroglobulin type-1 domain | Thyroglobulin type-1 domain | 3 | 2 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 3 | 3 | |
Zn-dependent exopeptidases | Carboxypeptidase regulatory domain-like | 3 | 2 | |
PHM/PNGase F | PHM/PNGase F | 3 | 3 | |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 3 | 2 | |
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | Multidrug efflux transporter AcrB transmembrane domain | 3 | 3 | |
PH domain-like | BEACH domain | 3 | 3 | |
Carbamoyl phosphate synthetase, large subunit connection domain | PreATP-grasp domain | 3 | 3 | |
PH domain-like | Oxysterol-binding protein-like | 3 | 3 | |
Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 3 | 3 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB transmembrane domain | 3 | 3 | |
ARM repeat | Hect, E3 ligase catalytic domain | 3 | 3 | |
Cysteine-rich DNA binding domain, (DM domain) | Cysteine-rich DNA binding domain, (DM domain) | 3 | 3 | |
Saposin | Metallo-dependent phosphatases | 3 | 2 | |
RING/U-box | Kelch motif | 3 | 1 | |
PX domain | Protein kinase-like (PK-like) | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Glucocorticoid receptor-like (DNA-binding domain) | 3 | 2 | |
Ankyrin repeat | RING/U-box | 3 | 3 | |
Protein kinase-like (PK-like) | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
Immunoglobulin | (Phosphotyrosine protein) phosphatases II | 3 | 3 | |
EF-hand | FAD-linked oxidoreductase | 3 | 1 | |
F-box domain | RNI-like | 3 | 2 | |
C-type lectin-like | EGF/Laminin | 3 | 3 | |
"Winged helix" DNA-binding domain | HRDC-like | 3 | 3 | |
MgtE membrane domain-like | MgtE membrane domain-like | 3 | 2 | |
STAT | p53-like transcription factors | 3 | 2 | |
Ubiquitin-like | "Winged helix" DNA-binding domain | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 3 | 2 | |
CCCH zinc finger | RNA-binding domain, RBD | 3 | 2 | |
Creatinase/aminopeptidase | "Winged helix" DNA-binding domain | 3 | 3 | |
Thioredoxin-like | FAD-dependent thiol oxidase | 3 | 1 | |
MetI-like | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
POZ domain | RING/U-box | 3 | 3 | |
EGF/Laminin | Lipocalins | 3 | 2 | |
ENTH/VHS domain | GAT-like domain | 3 | 2 | |
PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 3 | 2 | |
BRCT domain | DBL homology domain (DH-domain) | 3 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | WGR domain-like | 3 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 3 | 1 | |
Thiamin diphosphate-binding fold (THDP-binding) | DHS-like NAD/FAD-binding domain | 3 | 1 | |
FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 3 | 2 | |
LDL receptor-like module | Spermadhesin, CUB domain | 3 | 3 | |
HLH, helix-loop-helix DNA-binding domain | HLH, helix-loop-helix DNA-binding domain | 3 | 2 | |
HMA, heavy metal-associated domain | HMA, heavy metal-associated domain | 3 | 3 | |
Metalloproteases ("zincins"), catalytic domain | ARM repeat | 3 | 1 | |
B-box zinc-binding domain | NHL repeat | 3 | 3 | |
BEACH domain | WD40 repeat-like | 3 | 3 | |
Periplasmic binding protein-like I | Voltage-gated potassium channels | 3 | 3 | |
Glycoside hydrolase/deacetylase | Families 57/38 glycoside transferase middle domain | 3 | 2 | |
Protease propeptides/inhibitors | Subtilisin-like | 3 | 3 | |
EF-hand | RING/U-box | 3 | 3 | |
Glucocorticoid receptor-like (DNA-binding domain) | ADP-ribosylation | 3 | 2 | |
UDP-Glycosyltransferase/glycogen phosphorylase | UDP-Glycosyltransferase/glycogen phosphorylase | 3 | 1 | |
Protease propeptides/inhibitors | Galactose-binding domain-like | 3 | 3 | |
L domain-like | Growth factor receptor domain | 3 | 3 | |
Ribonuclease H-like | Nucleic acid-binding proteins | 2 | 2 | |
Oxidoreductase molybdopterin-binding domain | E set domains | 2 | 1 | |
Myosin rod fragments | Tropomyosin | 2 | 2 | |
Cytochrome b5-like heme/steroid binding domain | E set domains | 2 | 1 | |
RNA-binding domain, RBD | UBA-like | 2 | 1 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleic acid-binding proteins | 2 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | ACP-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Concanavalin A-like lectins/glucanases | 2 | 2 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 2 | 1 | |
p53-like transcription factors | DNA-binding protein LAG-1 (CSL) | 2 | 2 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Adenine nucleotide alpha hydrolases-like | 2 | 1 | |
DUSP-like | Cysteine proteinases | 2 | 2 | |
Plexin repeat | Integrin domains | 2 | 2 | |
UBC-like | UBA-like | 2 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | GTPase activation domain, GAP | 2 | 2 | |
FAD/NAD(P)-binding domain | EF-hand | 2 | 1 | |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | Nucleic acid-binding proteins | 2 | 1 | |
Protein kinase-like (PK-like) | PDZ domain-like | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | Citrate synthase | 2 | 1 | |
FMN-linked oxidoreductases | Alpha subunit of glutamate synthase, C-terminal domain | 2 | 2 | |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 2 | 2 | |
Nicotinate/Quinolinate PRTase N-terminal domain-like | Nicotinate/Quinolinate PRTase C-terminal domain-like | 2 | 2 | |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 2 | 1 | |
NTF2-like | UBA-like | 2 | 1 | |
EGF/Laminin | Ankyrin repeat | 2 | 2 | |
L domain-like | UBA-like | 2 | 1 | |
RNA-binding domain, RBD | Ran binding protein zinc finger-like | 2 | 2 | |
Acetyl-CoA synthetase-like | Acetyl-CoA synthetase-like | 2 | 2 | |
FabD/lysophospholipase-like | NAD(P)-binding Rossmann-fold domains | 2 | 2 | |
Methylglyoxal synthase-like | Cytidine deaminase-like | 2 | 2 | |
PurS-like | PurM N-terminal domain-like | 2 | 2 | |
PK beta-barrel domain-like | PK C-terminal domain-like | 2 | 1 | |
WW domain | PH domain-like | 2 | 2 | |
p53-like transcription factors | SH2 domain | 2 | 1 | |
E set domains | GTPase activation domain, GAP | 2 | 2 | |
Retrovirus zinc finger-like domains | DNA breaking-rejoining enzymes | 2 | 1 | |
Cadherin-like | EGF/Laminin | 2 | 2 | |
cAMP-binding domain-like | FabD/lysophospholipase-like | 2 | 2 | |
Immunoglobulin | TSP-1 type 1 repeat | 2 | 2 | |
alpha-helical ferredoxin | Nucleotide-binding domain | 2 | 2 | |
TSP-1 type 1 repeat | BPTI-like | 2 | 2 | |
PDZ domain-like | Second domain of FERM | 2 | 2 | |
DNA-binding protein LAG-1 (CSL) | E set domains | 2 | 2 | |
LDL receptor-like module | Trypsin-like serine proteases | 2 | 1 | |
Rad51 N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 | |
SH2 domain | Cysteine-rich domain | 2 | 2 | |
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain | Alkaline phosphatase-like | 2 | 1 | |
CoA-dependent acyltransferases | ACP-like | 2 | 2 | |
FMN-linked oxidoreductases | FAD/NAD(P)-binding domain | 2 | 2 | |
EF-hand | SH2 domain | 2 | 2 | |
RCC1/BLIP-II | Hect, E3 ligase catalytic domain | 2 | 2 | |
Transducin (heterotrimeric G protein), gamma chain | Regulator of G-protein signaling, RGS | 2 | 2 | |
ACP-like | alpha/beta-Hydrolases | 2 | 2 | |
Growth factor receptor domain | YWTD domain | 2 | 2 | |
Nucleic acid-binding proteins | Metallo-hydrolase/oxidoreductase | 2 | 2 | |
WW domain | FF domain | 2 | 2 | |
Cysteine-rich domain | DBL homology domain (DH-domain) | 2 | 2 | |
MIR domain | IP3 receptor type 1 binding core, domain 2 | 2 | 2 | |
Growth factor receptor domain | vWA-like | 2 | 2 | |
RNA-binding domain, RBD | ENTH/VHS domain | 2 | 2 | |
p53-like transcription factors | E set domains | 2 | 2 | |
beta-N-acetylhexosaminidase-like domain | (Trans)glycosidases | 2 | 2 | |
E set domains | AMPKBI-like | 2 | 2 | |
Composite domain of metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 2 | 1 | |
SNARE-like | SNARE fusion complex | 2 | 1 | |
"Winged helix" DNA-binding domain | GAF domain-like | 2 | 2 | |
ARM repeat | RING/U-box | 2 | 2 | |
Alkaline phosphatase-like | Alkaline phosphatase-like | 2 | 2 | |
HAD-like | BRCT domain | 2 | 1 | |
Activating enzymes of the ubiquitin-like proteins | Activating enzymes of the ubiquitin-like proteins | 2 | 2 | |
FAD-binding/transporter-associated domain-like | CO dehydrogenase flavoprotein C-terminal domain-like | 2 | 1 | |
L27 domain | PDZ domain-like | 2 | 2 | |
BAR/IMD domain-like | PH domain-like | 2 | 2 | |
alpha-helical ferredoxin | FMN-linked oxidoreductases | 2 | 2 | |
RNA-binding domain, RBD | PABC (PABP) domain | 2 | 1 | |
t-snare proteins | SNARE fusion complex | 2 | 1 | |
PH domain-like | HMG-box | 2 | 2 | |
Immunoglobulin | Growth factor receptor domain | 2 | 2 | |
Thyroglobulin type-1 domain | EF-hand | 2 | 2 | |
ARM repeat | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Glucocorticoid receptor-like (DNA-binding domain) | Family A G protein-coupled receptor-like | 2 | 2 | |
Chromo domain-like | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 | |
cAMP-binding domain-like | Ubiquitin-like | 2 | 2 | |
PA domain | Transferrin receptor-like dimerisation domain | 2 | 1 | |
CO dehydrogenase ISP C-domain like | CO dehydrogenase flavoprotein C-terminal domain-like | 2 | 1 | |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 2 | 2 | |
RNase III domain-like | dsRNA-binding domain-like | 2 | 2 | |
MoeA N-terminal region -like | Molybdenum cofactor biosynthesis proteins | 2 | 2 | |
Rudiment single hybrid motif | Aldolase | 2 | 2 | |
YWTD domain | YWTD domain | 2 | 2 | |
Triger factor/SurA peptide-binding domain-like | FKBP-like | 2 | 2 | |
"Winged helix" DNA-binding domain | Transducin (heterotrimeric G protein), gamma chain | 2 | 2 | |
vWA-like | SPOC domain-like | 2 | 1 | |
Concanavalin A-like lectins/glucanases | RING/U-box | 2 | 2 | |
Tricorn protease domain 2 | Protein kinase-like (PK-like) | 2 | 1 | |
TPR-like | Clavaminate synthase-like | 2 | 2 | |
WD40 repeat-like | RING/U-box | 2 | 2 | |
Notch domain | Ankyrin repeat | 2 | 2 | |
Regulator of G-protein signaling, RGS | Regulator of G-protein signaling, RGS | 2 | 2 | |
His-Me finger endonucleases | Ribonuclease H-like | 2 | 1 | |
Periplasmic binding protein-like II | Periplasmic binding protein-like II | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | WD40 repeat-like | 2 | 2 | |
ARM repeat | Ankyrin repeat | 2 | 2 | |
Second domain of FERM | Moesin tail domain | 2 | 2 | |
Single hybrid motif | ClpP/crotonase | 2 | 2 | |
GroES-like | GroES-like | 2 | 1 | |
Protein kinase-like (PK-like) | Polo-box domain | 2 | 2 | |
"Winged helix" DNA-binding domain | Regulator of G-protein signaling, RGS | 2 | 2 | |
RNase III domain-like | RNase III domain-like | 2 | 2 | |
4'-phosphopantetheinyl transferase | 4'-phosphopantetheinyl transferase | 2 | 1 | |
Zn-dependent exopeptidases | Transferrin receptor-like dimerisation domain | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | PRTase-like | 2 | 1 | |
Galactose-binding domain-like | beta-Galactosidase/glucuronidase domain | 2 | 2 | |
BEACH domain | FYVE/PHD zinc finger | 2 | 2 | |
Sec63 N-terminal domain-like | Sec63 N-terminal domain-like | 2 | 2 | |
Nucleic acid-binding proteins | "Winged helix" DNA-binding domain | 2 | 1 | |
Obg GTP-binding protein N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
PriA/YqbF domain | GINS helical bundle-like | 2 | 2 | |
FAD/NAD(P)-binding domain | Aminomethyltransferase beta-barrel domain | 2 | 2 | |
Elafin-like | BPTI-like | 2 | 2 | |
Ankyrin repeat | Eukaryotic type KH-domain (KH-domain type I) | 2 | 2 | |
PX domain | BAR/IMD domain-like | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | CYTH-like phosphatases | 2 | 1 | |
Rap30/74 interaction domains | "Winged helix" DNA-binding domain | 2 | 2 | |
Kix domain of CBP (creb binding protein) | Kix domain of CBP (creb binding protein) | 2 | 2 | |
Calponin-homology domain, CH-domain | EB1 dimerisation domain-like | 2 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
CoA-dependent acyltransferases | Acetyl-CoA synthetase-like | 2 | 2 | |
SAM/Pointed domain | Toll/Interleukin receptor TIR domain | 2 | 2 | |
L domain-like | Heme-dependent peroxidases | 2 | 1 | |
NAD(P)-binding Rossmann-fold domains | SCP-like | 2 | 1 | |
Ankyrin repeat | Galactose-binding domain-like | 2 | 2 | |
STAT | SH2 domain | 2 | 1 | |
Fibronectin type III | Concanavalin A-like lectins/glucanases | 2 | 2 | |
FAD-linked reductases, C-terminal domain | EF-hand | 2 | 1 | |
PRP4-like | Functional domain of the splicing factor Prp18 | 2 | 2 | |
Spermadhesin, CUB domain | Growth factor receptor domain | 2 | 2 | |
LysM domain | LysM domain | 2 | 2 | |
Plexin repeat | E set domains | 2 | 2 | |
Thiolase-like | NAD(P)-binding Rossmann-fold domains | 2 | 2 | |
E set domains | NHL repeat | 2 | 2 | |
RNI-like | L domain-like | 2 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | RBP11-like subunits of RNA polymerase | 2 | 1 | |
Succinyl-CoA synthetase domains | Citrate synthase | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Ubiquitin-like | 2 | 2 | |
Cysteine proteinases | Ribonuclease H-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | HAD-like | 2 | 2 | |
Acetyl-CoA synthetase-like | ACP-like | 2 | 2 | |
ARM repeat | Subdomain of clathrin and coatomer appendage domain | 2 | 2 | |
Kringle-like | Trypsin-like serine proteases | 2 | 1 | |
PA domain | Zn-dependent exopeptidases | 2 | 1 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleotidylyl transferase | 2 | 1 | |
Homeodomain-like | FAD-linked reductases, C-terminal domain | 2 | 1 | |
Growth factor receptor domain | Fibronectin type III | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Second domain of FERM | 2 | 2 | |
Cytochrome b5-like heme/steroid binding domain | Oxidoreductase molybdopterin-binding domain | 2 | 1 | |
C-type lectin-like | Kringle-like | 2 | 1 | |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | DNA/RNA polymerases | 2 | 2 | |
Ribosomal L27 protein-like | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 2 | 1 | |
Concanavalin A-like lectins/glucanases | P-domain of calnexin/calreticulin | 2 | 1 | |
(Phosphotyrosine protein) phosphatases II | FYVE/PHD zinc finger | 2 | 2 | |
Calpain large subunit, middle domain (domain III) | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 1 | |
C-type lectin-like | Complement control module/SCR domain | 2 | 2 | |
Thiolase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 2 | 2 | |
ACP-like | ACP-like | 2 | 2 | |
Cytochrome P450 | Cytochrome P450 | 2 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | WW domain | 2 | 2 | |
TAZ domain | Kix domain of CBP (creb binding protein) | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | ClpP/crotonase | 2 | 2 | |
Hairpin loop containing domain-like | Trypsin-like serine proteases | 2 | 1 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | 2 | 2 | |
ACP-like | ALDH-like | 2 | 1 | |
Macro domain-like | Cysteine proteinases | 2 | 1 | |
FAD/NAD(P)-binding domain | Folate-binding domain | 2 | 2 | |
Spermadhesin, CUB domain | vWA-like | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | E set domains | 2 | 2 | |
SAM/Pointed domain | PH domain-like | 2 | 2 | |
Immunoglobulin | vWA-like | 2 | 2 | |
C-type lectin-like | Trypsin-like serine proteases | 2 | 1 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | SMAD/FHA domain | 2 | 2 | |
NagB/RpiA/CoA transferase-like | D-ribose-5-phosphate isomerase (RpiA), lid domain | 2 | 1 | |
WD40 repeat-like | FYVE/PHD zinc finger | 2 | 2 | |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 2 | 1 | |
PH domain-like | WD40 repeat-like | 2 | 2 | |
Phosphofructokinase | Phosphofructokinase | 2 | 1 | |
TPR-like | Chaperone J-domain | 2 | 2 | |
HIT/MYND zinc finger-like | Creatinase/aminopeptidase | 2 | 1 | |
CCCH zinc finger | RING/U-box | 2 | 2 | |
Periplasmic binding protein-like II | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Sema domain | GTPase activation domain, GAP | 2 | 2 | |
ARID-like | Clavaminate synthase-like | 2 | 2 | |
Regulator of G-protein signaling, RGS | PX domain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | GTPase activation domain, GAP | 2 | 2 | |
beta-beta-alpha zinc fingers | Homeodomain-like | 2 | 2 | |
Kelch motif | Kelch motif | 2 | 2 | |
SRCR-like | Trypsin-like serine proteases | 2 | 1 | |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | Tryptophan synthase beta subunit-like PLP-dependent enzymes | 2 | 1 | |
Rudiment single hybrid motif | ClpP/crotonase | 2 | 2 | |
Tex N-terminal region-like | Nucleic acid-binding proteins | 2 | 2 | |
POZ domain | Cyclin-like | 2 | 2 | |
DEATH domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Ribonuclease H-like | RuvA domain 2-like | 2 | 2 | |
RNA-binding domain, RBD | Cyclophilin-like | 2 | 2 | |
PurS-like | PurM C-terminal domain-like | 2 | 2 | |
Carbon-nitrogen hydrolase | Adenine nucleotide alpha hydrolases-like | 2 | 2 | |
LDL receptor-like module | SRCR-like | 2 | 1 | |
Fumarylacetoacetate hydrolase, FAH, N-terminal domain | FAH | 2 | 1 | |
Translation proteins | ThrRS/AlaRS common domain | 2 | 1 | |
Thiolase-like | ACP-like | 2 | 2 | |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 2 | 2 | |
ARM repeat | Galactose-binding domain-like | 2 | 2 | |
Regulator of G-protein signaling, RGS | Protein kinase-like (PK-like) | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 2 | 2 | |
POZ domain | F-box domain | 2 | 1 | |
Surp module (SWAP domain) | Surp module (SWAP domain) | 2 | 2 | |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 2 | 1 | |
Regulator of G-protein signaling, RGS | Ubiquitin-like | 2 | 1 | |
Nucleotide-diphospho-sugar transferases | Trimeric LpxA-like enzymes | 2 | 2 | |
Calponin-homology domain, CH-domain | EF-hand | 2 | 2 | |
Periplasmic binding protein-like II | MetI-like | 2 | 2 | |
N-terminal domain of adenylylcyclase associated protein, CAP | C-terminal domain of adenylylcyclase associated protein | 2 | 2 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Glutathione synthetase ATP-binding domain-like | 2 | 2 | |
Galactose-binding domain-like | Hect, E3 ligase catalytic domain | 2 | 2 | |
BPTI-like | EGF/Laminin | 2 | 2 | |
YVTN repeat-like/Quinoprotein amine dehydrogenase | Protein kinase-like (PK-like) | 2 | 1 | |
Formyltransferase | FMT C-terminal domain-like | 2 | 1 | |
ARID-like | FYVE/PHD zinc finger | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | NAD(P)-binding Rossmann-fold domains | 2 | 1 | |
Polo-box domain | Polo-box domain | 2 | 2 | |
Complement control module/SCR domain | EGF/Laminin | 2 | 2 | |
Spectrin repeat | Immunoglobulin | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 2 | 2 | |
Adhesin YadA, collagen-binding domain | Adhesin YadA, collagen-binding domain | 2 | 2 | |
Kringle-like | Hairpin loop containing domain-like | 2 | 1 | |
NAD(P)-binding Rossmann-fold domains | Citrate synthase | 2 | 1 | |
Ankyrin repeat | Hect, E3 ligase catalytic domain | 2 | 2 | |
WW domain | GTPase activation domain, GAP | 2 | 2 | |
THUMP domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 | |
FabD/lysophospholipase-like | ACP-like | 2 | 2 | |
SAM/Pointed domain | "Winged helix" DNA-binding domain | 2 | 1 | |
Kringle-like | LDL receptor-like module | 2 | 1 | |
Integrin alpha N-terminal domain | Integrin domains | 2 | 2 | |
FnI-like domain | Growth factor receptor domain | 2 | 2 | |
Cysteine proteinases | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 1 | |
RING/U-box | BRCT domain | 2 | 2 | |
His-Me finger endonucleases | DNA/RNA polymerases | 2 | 1 | |
WD40 repeat-like | Tricorn protease domain 2 | 2 | 2 | |
GAF domain-like | HD-domain/PDEase-like | 2 | 2 | |
Thiolase-like | FabD/lysophospholipase-like | 2 | 2 | |
FF domain | FF domain | 2 | 2 | |
FYVE/PHD zinc finger | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 | |
Type II DNA topoisomerase | GyrA/ParC C-terminal domain-like | 2 | 2 | |
POZ domain | RNA-binding domain, RBD | 2 | 1 | |
Ypt/Rab-GAP domain of gyp1p | RUN domain-like | 2 | 2 | |
Tropomyosin | Tropomyosin | 2 | 2 | |
Nucleotidylyl transferase | Nucleic acid-binding proteins | 2 | 1 | |
FGAM synthase PurL, linker domain | PurM C-terminal domain-like | 2 | 2 | |
Class II aaRS and biotin synthetases | Translation proteins | 2 | 1 | |
Sec7 domain | ARM repeat | 2 | 2 | |
Immunoglobulin | Heme-dependent peroxidases | 2 | 1 | |
Formyltransferase | ALDH-like | 2 | 1 | |
EF-hand | Cysteine-rich domain | 2 | 2 | |
GDNF receptor-like | GDNF receptor-like | 2 | 2 | |
Adenine nucleotide alpha hydrolases-like | DHS-like NAD/FAD-binding domain | 2 | 1 | |
SH2 domain | (Phosphotyrosine protein) phosphatases II | 2 | 2 | |
FMT C-terminal domain-like | ACP-like | 2 | 1 | |
CO dehydrogenase flavoprotein C-terminal domain-like | CO dehydrogenase molybdoprotein N-domain-like | 2 | 1 | |
TPR-like | RING/U-box | 2 | 2 | |
FMT C-terminal domain-like | ALDH-like | 2 | 1 | |
Ribonuclease H-like | HRDC-like | 2 | 2 | |
Plexin repeat | GTPase activation domain, GAP | 2 | 2 | |
Immunoglobulin | DEATH domain | 2 | 2 | |
Sema domain | E set domains | 2 | 2 | |
C-type lectin-like | Fibronectin type III | 2 | 2 | |
LDL receptor-like module | Hairpin loop containing domain-like | 2 | 1 | |
Calponin-homology domain, CH-domain | SH3-domain | 2 | 2 | |
Trefoil | Galactose mutarotase-like | 2 | 1 | |
Translational machinery components | L30e-like | 2 | 2 | |
Ubiquitin-like | Moesin tail domain | 2 | 2 | |
Band 7/SPFH domain | SCP-like | 2 | 2 | |
Chaperone J-domain | Thioredoxin-like | 2 | 2 | |
Kringle-like | SRCR-like | 2 | 1 | |
FGAM synthase PurL, linker domain | PurM N-terminal domain-like | 2 | 2 | |
Tropomyosin | Lamin A/C globular tail domain | 2 | 2 | |
HLH, helix-loop-helix DNA-binding domain | PYP-like sensor domain (PAS domain) | 2 | 2 | |
Starch-binding domain-like | PLC-like phosphodiesterases | 2 | 2 | |
Tex N-terminal region-like | RuvA domain 2-like | 2 | 2 | |
PH domain-like | Moesin tail domain | 2 | 2 | |
Integrin domains | Integrin domains | 2 | 2 | |
"Winged helix" DNA-binding domain | E set domains | 2 | 2 | |
Complement control module/SCR domain | Growth factor receptor domain | 2 | 2 | |
UBA-like | Cysteine proteinases | 2 | 2 | |
Methylated DNA-protein cysteine methyltransferase domain | Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 2 | 2 | |
PurS-like | FGAM synthase PurL, linker domain | 2 | 2 | |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 2 | 2 | |
LDL receptor-like module | Immunoglobulin | 2 | 2 | |
Clathrin adaptor appendage domain | Subdomain of clathrin and coatomer appendage domain | 2 | 2 | |
Complement control module/SCR domain | Galactose-binding domain-like | 2 | 2 | |
NAD(P)-binding Rossmann-fold domains | ACP-like | 2 | 2 | |
Voltage-gated potassium channels | E set domains | 2 | 1 | |
cAMP-binding domain-like | Ras GEF | 2 | 2 | |
Voltage-gated potassium channels | Fibronectin type III | 2 | 1 | |
RuvA domain 2-like | RuvA domain 2-like | 2 | 2 | |
Translation proteins | Initiation factor IF2/eIF5b, domain 3 | 2 | 2 | |
Chaperone J-domain | Homeodomain-like | 2 | 2 | |
Nucleotide-diphospho-sugar transferases | Nucleotide-diphospho-sugar transferases | 2 | 2 | |
Regulator of G-protein signaling, RGS | PH domain-like | 2 | 2 | |
FnI-like domain | FnI-like domain | 2 | 2 | |
Hairpin loop containing domain-like | SRCR-like | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | vWA-like | 2 | 2 | |
beta-Galactosidase/glucuronidase domain | (Trans)glycosidases | 2 | 2 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Hect, E3 ligase catalytic domain | 2 | 2 | |
cAMP-binding domain-like | Protein kinase-like (PK-like) | 2 | 2 | |
Protein kinase-like (PK-like) | SAM/Pointed domain | 2 | 2 | |
Notch domain | Notch domain | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | Aldolase | 2 | 2 | |
SH3-domain | GTPase activation domain, GAP | 2 | 2 | |
Ypt/Rab-GAP domain of gyp1p | Rhodanese/Cell cycle control phosphatase | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 2 | 2 | |
PGBD-like | Hemopexin-like domain | 2 | 2 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | NAD(P)-binding Rossmann-fold domains | 2 | 2 | |
Tex N-terminal region-like | Ribonuclease H-like | 2 | 2 | |
ISP domain | Bet v1-like | 2 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 2 | 1 | |
ISP transmembrane anchor | ISP domain | 2 | 2 | |
Ubiquitin-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 | |
Hormone receptor domain | Family A G protein-coupled receptor-like | 2 | 2 | |
CO dehydrogenase flavoprotein C-terminal domain-like | Molybdenum cofactor-binding domain | 2 | 1 | |
TATA-box binding protein-like | TATA-box binding protein-like | 2 | 2 | |
MIR domain | MIR domain | 2 | 2 | |
N-terminal, heterodimerisation domain of RBP7 (RpoE) | Nucleic acid-binding proteins | 2 | 1 | |
2Fe-2S ferredoxin-like | CO dehydrogenase flavoprotein C-terminal domain-like | 2 | 1 | |
HMA, heavy metal-associated domain | HAD-like | 2 | 2 | |
Formyltransferase | ACP-like | 2 | 1 | |
Nucleotide-binding domain | FMN-linked oxidoreductases | 2 | 2 | |
Family A G protein-coupled receptor-like | Nuclear receptor ligand-binding domain | 2 | 2 | |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | Zinc-binding domain of translation initiation factor 2 beta | 2 | 2 | |
PH domain-like | ArfGap/RecO-like zinc finger | 2 | 2 | |
TPR-like | Fic-like | 2 | 1 | |
Intermediate filament protein, coiled coil region | Tropomyosin | 2 | 2 | |
EGF/Laminin | Notch domain | 2 | 2 | |
Homeodomain-like | Tetracyclin repressor-like, C-terminal domain | 1 | 1 | |
RNA-binding domain, RBD | PWI domain | 1 | 1 | |
PurM C-terminal domain-like | Class I glutamine amidotransferase-like | 1 | 1 | |
Homeodomain-like | SET domain | 1 | 1 | |
Ankyrin repeat | WD40 repeat-like | 1 | 1 | |
B-box zinc-binding domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Aldolase | post-HMGL domain-like | 1 | 1 | |
FYVE/PHD zinc finger | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
Glycosyl hydrolase domain | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
ARM repeat | Toll/Interleukin receptor TIR domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Microbial and mitochondrial ADK, insert "zinc finger" domain | 1 | 1 | |
WW domain | FKBP-like | 1 | 1 | |
Radical SAM enzymes | Molybdenum cofactor biosynthesis protein C, MoaC | 1 | 1 | |
Family A G protein-coupled receptor-like | SMR domain-like | 1 | 1 | |
Cobalamin (vitamin B12)-dependent enzymes | Cobalamin (vitamin B12)-dependent enzymes | 1 | 1 | |
RNA-binding domain, RBD | DNA/RNA polymerases | 1 | 1 | |
(Trans)glycosidases | Glutamine synthetase/guanido kinase | 1 | 1 | |
Alpha subunit of glutamate synthase, C-terminal domain | Nucleotide-binding domain | 1 | 1 | |
Radical SAM enzymes | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
Tim10-like | Ribonuclease PH domain 2-like | 1 | 1 | |
Growth factor receptor domain | Leech antihemostatic proteins | 1 | 1 | |
Nucleoporin domain | Tubby C-terminal domain-like | 1 | 1 | |
Ubiquitin-like | A middle domain of Talin 1 | 1 | 1 | |
Ran binding protein zinc finger-like | Ran binding protein zinc finger-like | 1 | 1 | |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Fzo-like conserved region | 1 | 1 | |
Class II aaRS and biotin synthetases | GAD domain-like | 1 | 1 | |
Cobalamin (vitamin B12)-dependent enzymes | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
Elafin-like | Complement control module/SCR domain | 1 | 1 | |
Nqo1 FMN-binding domain-like | Nqo1C-terminal domain-like | 1 | 1 | |
FKBP-like | EF-hand | 1 | 1 | |
Ribonuclease PH domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
TPR-like | ARM repeat | 1 | 1 | |
RNI-like | Family A G protein-coupled receptor-like | 1 | 1 | |
PRP4-like | WD40 repeat-like | 1 | 1 | |
RCC1/BLIP-II | ARM repeat | 1 | 1 | |
RING/U-box | Cyclophilin-like | 1 | 1 | |
Bromodomain | HMG-box | 1 | 1 | |
CCCH zinc finger | beta-sandwich domain of Sec23/24 | 1 | 1 | |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Zinc beta-ribbon | 1 | 1 | |
Myosin rod fragments | Lamin A/C globular tail domain | 1 | 1 | |
TAZ domain | TAZ domain | 1 | 1 | |
Ubiquitin-like | alpha-catenin/vinculin-like | 1 | 1 | |
(Trans)glycosidases | DNase I-like | 1 | 1 | |
Quinoprotein alcohol dehydrogenase-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
Second domain of FERM | FAT domain of focal adhesion kinase | 1 | 1 | |
Complement control module/SCR domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
MCP/YpsA-like | YrdC/RibB | 1 | 1 | |
MAST3 pre-PK domain-like | PDZ domain-like | 1 | 1 | |
Nucleotidylyl transferase | S15/NS1 RNA-binding domain | 1 | 1 | |
ARM repeat | Mib/herc2 domain-like | 1 | 1 | |
Clathrin heavy-chain terminal domain | ARM repeat | 1 | 1 | |
Ubiquitin-like | Cap-Gly domain | 1 | 1 | |
ISP domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 1 | 1 | |
Galactose oxidase, central domain | EGF/Laminin | 1 | 1 | |
Saposin | Voltage-gated potassium channels | 1 | 1 | |
PAP/OAS1 substrate-binding domain | Retrovirus zinc finger-like domains | 1 | 1 | |
CAD & PB1 domains | Cysteine-rich domain | 1 | 1 | |
Calpain large subunit, middle domain (domain III) | Calpain large subunit, middle domain (domain III) | 1 | 1 | |
PurM N-terminal domain-like | Class I glutamine amidotransferase-like | 1 | 1 | |
ARM repeat | SAM/Pointed domain | 1 | 1 | |
MIT domain | Calpain large subunit, middle domain (domain III) | 1 | 1 | |
PapD-like | BAR/IMD domain-like | 1 | 1 | |
Integrin domains | Integrin beta tail domain | 1 | 1 | |
PH domain-like | Ras GEF | 1 | 1 | |
TPR-like | Metallo-dependent phosphatases | 1 | 1 | |
DNA clamp | DNA clamp | 1 | 1 | |
PAP/OAS1 substrate-binding domain | PapD-like | 1 | 1 | |
PDZ domain-like | Regulator of G-protein signaling, RGS | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
TROVE domain-like | vWA-like | 1 | 1 | |
Granulin repeat | Granulin repeat | 1 | 1 | |
Homeodomain-like | F-box domain | 1 | 1 | |
Spectrin repeat | Fibronectin type III | 1 | 1 | |
Acid proteases | Protein kinase-like (PK-like) | 1 | 1 | |
Tricorn protease N-terminal domain | Tricorn protease N-terminal domain | 1 | 1 | |
Mannose 6-phosphate receptor domain | Mannose 6-phosphate receptor domain | 1 | 1 | |
DNA repair protein MutS, domain I | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FKBP-like | TPR-like | 1 | 1 | |
Ankyrin repeat | Second domain of FERM | 1 | 1 | |
Elafin-like | Leech antihemostatic proteins | 1 | 1 | |
CRAL/TRIO N-terminal domain | PapD-like | 1 | 1 | |
DBL homology domain (DH-domain) | DBL homology domain (DH-domain) | 1 | 1 | |
Thioredoxin-like | "Winged helix" DNA-binding domain | 1 | 1 | |
RCC1/BLIP-II | RING/U-box | 1 | 1 | |
Ubiquitin-like | GTPase activation domain, GAP | 1 | 1 | |
Kazal-type serine protease inhibitors | EF-hand | 1 | 1 | |
Homeodomain-like | Nucleic acid-binding proteins | 1 | 1 | |
Inhibitor of apoptosis (IAP) repeat | Inhibitor of apoptosis (IAP) repeat | 1 | 1 | |
DnaK suppressor protein DksA, alpha-hairpin domain | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | Nucleic acid-binding proteins | 1 | 1 | |
"Winged helix" DNA-binding domain | alpha/beta knot | 1 | 1 | |
Kelch motif | EGF/Laminin | 1 | 1 | |
tRNA-binding arm | Class II aaRS and biotin synthetases | 1 | 1 | |
ARM repeat | PX domain | 1 | 1 | |
ERH-like | ARM repeat | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | lambda repressor-like DNA-binding domains | 1 | 1 | |
PDZ domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
R3H domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase activation domain-like | 1 | 1 | |
RNI-like | PDZ domain-like | 1 | 1 | |
IP3 receptor type 1 binding core, domain 2 | IP3 receptor type 1 binding core, domain 2 | 1 | 1 | |
(Trans)glycosidases | Invertebrate chitin-binding proteins | 1 | 1 | |
Serine protease inhibitors | EGF/Laminin | 1 | 1 | |
PDZ domain-like | GTPase activation domain, GAP | 1 | 1 | |
Ran binding protein zinc finger-like | Cysteine proteinases | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | Acetyl-CoA synthetase-like | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | F-box domain | 1 | 1 | |
alpha/beta-Hydrolases | p53-like transcription factors | 1 | 1 | |
Acetyl-CoA synthetase-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
Carbamate kinase-like | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | 1 | |
PreATP-grasp domain | Formyltransferase | 1 | 1 | |
Pre-PUA domain | PUA domain-like | 1 | 1 | |
2Fe-2S ferredoxin-like | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Carbon-nitrogen hydrolase | HIT-like | 1 | 1 | |
alpha/beta-Hydrolases | L domain-like | 1 | 1 | |
SH2 domain | RING/U-box | 1 | 1 | |
Nucleotidylyl transferase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
L domain-like | Calponin-homology domain, CH-domain | 1 | 1 | |
Skp1 dimerisation domain-like | Skp1 dimerisation domain-like | 1 | 1 | |
Double Clp-N motif | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FYVE/PHD zinc finger | SAICAR synthase-like | 1 | 1 | |
PHM/PNGase F | NHL repeat | 1 | 1 | |
PR-1-like | C-type lectin-like | 1 | 1 | |
Indigoidine synthase A-like | Indigoidine synthase A-like | 1 | 1 | |
B-box zinc-binding domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Cadherin-like | 1 | 1 | |
GFP-like | YWTD domain | 1 | 1 | |
Protein kinase-like (PK-like) | Acyl-CoA dehydrogenase C-terminal domain-like | 1 | 1 | |
Spermadhesin, CUB domain | Galactose-binding domain-like | 1 | 1 | |
YbiA-like | Thiolase-like | 1 | 1 | |
Globin-like | Riboflavin synthase domain-like | 1 | 1 | |
cAMP-binding domain-like | PDZ domain-like | 1 | 1 | |
Nucleic acid-binding proteins | eIF-2-alpha, C-terminal domain | 1 | 1 | |
beta-beta-alpha zinc fingers | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
PRTase-like | PRTase-like | 1 | 1 | |
PheT/TilS domain | Class II aaRS and biotin synthetases | 1 | 1 | |
GroES-like | alpha/beta-Hydrolases | 1 | 1 | |
CRAL/TRIO domain | Spectrin repeat | 1 | 1 | |
Tudor/PWWP/MBT | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Cysteine proteinases | Xylose isomerase-like | 1 | 1 | |
EF-hand | Riboflavin synthase domain-like | 1 | 1 | |
Ypt/Rab-GAP domain of gyp1p | SH3-domain | 1 | 1 | |
Phosphoenolpyruvate/pyruvate domain | Malate synthase G | 1 | 1 | |
Glycosyl hydrolase domain | DNA/RNA polymerases | 1 | 1 | |
Voltage-gated potassium channels | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Second domain of FERM | alpha-catenin/vinculin-like | 1 | 1 | |
Protein kinase-like (PK-like) | Rhodanese/Cell cycle control phosphatase | 1 | 1 | |
Ribosomal protein S5 domain 2-like | GyrA/ParC C-terminal domain-like | 1 | 1 | |
Arginase/deacetylase | RING/U-box | 1 | 1 | |
Spectrin repeat | DBL homology domain (DH-domain) | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Nucleotide cyclase | 1 | 1 | |
SAM/Pointed domain | GTPase activation domain, GAP | 1 | 1 | |
Retrovirus zinc finger-like domains | Homeodomain-like | 1 | 1 | |
Thiolase-like | Acetyl-CoA synthetase-like | 1 | 1 | |
Ankyrin repeat | PDZ domain-like | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase activation domain-like | 1 | 1 | |
PX domain | MIT domain | 1 | 1 | |
Ubiquitin-like | SMAD/FHA domain | 1 | 1 | |
Formin homology 2 domain (FH2 domain) | HIT/MYND zinc finger-like | 1 | 1 | |
Ubiquitin-like | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
TGS-like | ThrRS/AlaRS common domain | 1 | 1 | |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
TGS-like | Class II aaRS and biotin synthetases | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | PurM N-terminal domain-like | 1 | 1 | |
MIT domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
PreATP-grasp domain | Aldolase | 1 | 1 | |
SH3-domain | SAM/Pointed domain | 1 | 1 | |
Soluble quinoprotein glucose dehydrogenase | vWA-like | 1 | 1 | |
ATP-dependent DNA ligase DNA-binding domain | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 | |
Snake toxin-like | Protein kinase-like (PK-like) | 1 | 1 | |
ERH-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Putative DNA-binding domain | Cation efflux protein transmembrane domain-like | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Spectrin repeat | WW domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | beta-beta-alpha zinc fingers | 1 | 1 | |
Metal cation-transporting ATPase, ATP-binding domain N | Metal cation-transporting ATPase, ATP-binding domain N | 1 | 1 | |
Cysteine proteinases | Protein kinase-like (PK-like) | 1 | 1 | |
CAD & PB1 domains | Protein kinase-like (PK-like) | 1 | 1 | |
Histone-fold | Ras GEF | 1 | 1 | |
MIR domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Protein kinase-like (PK-like) | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
DNA-binding domain | FYVE/PHD zinc finger | 1 | 1 | |
Rudiment single hybrid motif | PurM C-terminal domain-like | 1 | 1 | |
L domain-like | C-terminal, gelsolin-like domain of Sec23/24 | 1 | 1 | |
TPR-like | RNA-binding domain, RBD | 1 | 1 | |
RUN domain-like | RUN domain-like | 1 | 1 | |
Quinoprotein alcohol dehydrogenase-like | Protein kinase-like (PK-like) | 1 | 1 | |
Calponin-homology domain, CH-domain | WW domain | 1 | 1 | |
FabD/lysophospholipase-like | CoA-dependent acyltransferases | 1 | 1 | |
C-type lectin-like | Immunoglobulin | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | WW domain | 1 | 1 | |
SH2 domain | SOCS box-like | 1 | 1 | |
Ankyrin repeat | SOCS box-like | 1 | 1 | |
FYVE/PHD zinc finger | GroEL apical domain-like | 1 | 1 | |
Ubiquitin-like | FAT domain of focal adhesion kinase | 1 | 1 | |
Bromodomain | RING/U-box | 1 | 1 | |
Pectin lyase-like | C-type lectin-like | 1 | 1 | |
Fibronectin type III | Calcium-dependent phosphotriesterase | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Periplasmic binding protein-like I | 1 | 1 | |
PDZ domain-like | DBL homology domain (DH-domain) | 1 | 1 | |
Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, substrate-binding domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Phosphohistidine domain | 1 | 1 | |
Folate-binding domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
PR-1-like | TRAF domain-like | 1 | 1 | |
Elafin-like | Elafin-like | 1 | 1 | |
Aldolase | Single hybrid motif | 1 | 1 | |
Mitochondrial carrier | Mitochondrial carrier | 1 | 1 | |
GTPase activation domain, GAP | VPS9 domain | 1 | 1 | |
FMN-linked oxidoreductases | 4Fe-4S ferredoxins | 1 | 1 | |
Fic-like | "Winged helix" DNA-binding domain | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Growth factor receptor domain | 1 | 1 | |
Calponin-homology domain, CH-domain | Cysteine-rich domain | 1 | 1 | |
Spectrin repeat | Plakin repeat | 1 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | C-terminal domain of PLC-beta | 1 | 1 | |
PDZ domain-like | BAR/IMD domain-like | 1 | 1 | |
DNA polymerase beta, N-terminal domain-like | Restriction endonuclease-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Class II aaRS and biotin synthetases | 1 | 1 | |
CCHHC domain | CCHHC domain | 1 | 1 | |
SH2 domain | ARM repeat | 1 | 1 | |
L domain-like | PP2C-like | 1 | 1 | |
Phosphohistidine domain | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
eIF2alpha middle domain-like | eIF-2-alpha, C-terminal domain | 1 | 1 | |
PRTase-like | Ribulose-phoshate binding barrel | 1 | 1 | |
Cysteine proteinases | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
BRCT domain | DNA-glycosylase | 1 | 1 | |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase domain | 1 | 1 | |
LDL receptor-like module | RNI-like | 1 | 1 | |
FAS1 domain | FAS1 domain | 1 | 1 | |
YegP-like | YegP-like | 1 | 1 | |
Hypothetical protein c14orf129, hspc210 | TPR-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Actin-like ATPase domain | 1 | 1 | |
PH domain-like | Fibronectin type III | 1 | 1 | |
Zn-dependent exopeptidases | DNA breaking-rejoining enzymes | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | VPS9 domain | 1 | 1 | |
Zinc beta-ribbon | Prokaryotic SH3-related domain | 1 | 1 | |
Histone-fold | Retrovirus zinc finger-like domains | 1 | 1 | |
Galactose-binding domain-like | C-type lectin-like | 1 | 1 | |
Cadherin-like | Hormone receptor domain | 1 | 1 | |
UBC-like | Class II aaRS and biotin synthetases | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
Class II aaRS ABD-related | Nucleotidyltransferase | 1 | 1 | |
SH2 domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain III | 1 | 1 | |
E set domains | Complement control module/SCR domain | 1 | 1 | |
PR-1-like | POZ domain | 1 | 1 | |
Ubiquitin-like | I/LWEQ domain | 1 | 1 | |
L27 domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
SEA domain | vWA-like | 1 | 1 | |
Thiolase-like | GroES-like | 1 | 1 | |
Nucleic acid-binding proteins | TPR-like | 1 | 1 | |
Acyl-CoA dehydrogenase NM domain-like | Metallo-hydrolase/oxidoreductase | 1 | 1 | |
Immunoglobulin | Caspase-like | 1 | 1 | |
PH domain-like | BSD domain-like | 1 | 1 | |
LDL receptor-like module | Complement control module/SCR domain | 1 | 1 | |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 1 | 1 | |
MFS general substrate transporter | MFS general substrate transporter | 1 | 1 | |
Globin-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
Ankyrin repeat | beta-N-acetylhexosaminidase-like domain | 1 | 1 | |
Taf5 N-terminal domain-like | WD40 repeat-like | 1 | 1 | |
Methylglyoxal synthase-like | Metallo-dependent hydrolases | 1 | 1 | |
Alpha subunit of glutamate synthase, C-terminal domain | alpha-helical ferredoxin | 1 | 1 | |
WD40 repeat-like | Cysteine proteinases | 1 | 1 | |
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain | WD40 repeat-like | 1 | 1 | |
Diaminopimelate epimerase-like | Diaminopimelate epimerase-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
Cysteine proteinases | SET domain | 1 | 1 | |
Ribonuclease PH domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Cysteine proteinases | ALDH-like | 1 | 1 | |
Cap-Gly domain | L domain-like | 1 | 1 | |
FtsH protease domain-like | Tropomyosin | 1 | 1 | |
A middle domain of Talin 1 | Phase 1 flagellin | 1 | 1 | |
EGF/Laminin | Soluble quinoprotein glucose dehydrogenase | 1 | 1 | |
"Winged helix" DNA-binding domain | Ras GEF | 1 | 1 | |
Chromo domain-like | Ankyrin repeat | 1 | 1 | |
Galactose oxidase, central domain | Fibronectin type III | 1 | 1 | |
Thioredoxin-like | Galactose-binding domain-like | 1 | 1 | |
BPTI-like | Immunoglobulin | 1 | 1 | |
PurM N-terminal domain-like | Formyltransferase | 1 | 1 | |
HAD-like | Acyl-CoA dehydrogenase NM domain-like | 1 | 1 | |
Leech antihemostatic proteins | BPTI-like | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | Bromodomain | 1 | 1 | |
DBL homology domain (DH-domain) | Ras GEF | 1 | 1 | |
p53-like transcription factors | p53-like transcription factors | 1 | 1 | |
E set domains | (Trans)glycosidases | 1 | 1 | |
UBA-like | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 | |
Methylglyoxal synthase-like | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
Rudiment single hybrid motif | PurM N-terminal domain-like | 1 | 1 | |
Calponin-homology domain, CH-domain | DBL homology domain (DH-domain) | 1 | 1 | |
HR1 repeat | HR1 repeat | 1 | 1 | |
Ypt/Rab-GAP domain of gyp1p | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
HCP-like | HCP-like | 1 | 1 | |
PreATP-grasp domain | PurM N-terminal domain-like | 1 | 1 | |
Dihydropteroate synthetase-like | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
alpha/beta-Hydrolases | Cytochrome P450 | 1 | 1 | |
I/LWEQ domain | Phase 1 flagellin | 1 | 1 | |
LDL receptor-like module | EF-hand | 1 | 1 | |
PH domain-like | Immunoglobulin | 1 | 1 | |
Elafin-like | Fibronectin type III | 1 | 1 | |
FYSH domain | Hypothetical protein AF0491, middle domain | 1 | 1 | |
ISP domain | FAD/NAD(P)-binding domain | 1 | 1 | |
Surp module (SWAP domain) | ENTH/VHS domain | 1 | 1 | |
FabD/lysophospholipase-like | alpha/beta-Hydrolases | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | alpha/beta-Hydrolases | 1 | 1 | |
L domain-like | Fibronectin type III | 1 | 1 | |
Ubiquitin-like | NAD kinase/diacylglycerol kinase-like | 1 | 1 | |
L30e-like | alpha/beta knot | 1 | 1 | |
Endosomal sorting complex assembly domain | VPS28 C-terminal domain-like | 1 | 1 | |
Kringle-like | Protein kinase-like (PK-like) | 1 | 1 | |
PH domain-like | Phospholipase D/nuclease | 1 | 1 | |
Calcium-dependent phosphotriesterase | Calcium-dependent phosphotriesterase | 1 | 1 | |
Concanavalin A-like lectins/glucanases | IP3 receptor type 1 binding core, domain 2 | 1 | 1 | |
HAND domain of the nucleosome remodeling ATPase ISWI | Homeodomain-like | 1 | 1 | |
Family A G protein-coupled receptor-like | Cystine-knot cytokines | 1 | 1 | |
lambda repressor-like DNA-binding domains | F-box domain | 1 | 1 | |
Regulator of G-protein signaling, RGS | DBL homology domain (DH-domain) | 1 | 1 | |
EGF/Laminin | Calcium-dependent phosphotriesterase | 1 | 1 | |
GST C-terminal domain-like | Phosphoglycerate mutase-like | 1 | 1 | |
Ricin B-like lectins | Cadherin-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Class I glutamine amidotransferase-like | 1 | 1 | |
Bet v1-like | HAD-like | 1 | 1 | |
UBA-like | XPC-binding domain | 1 | 1 | |
Calponin-homology domain, CH-domain | Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | 1 | |
LDL receptor-like module | vWA-like | 1 | 1 | |
Family A G protein-coupled receptor-like | RING/U-box | 1 | 1 | |
Nucleic acid-binding proteins | DNA-glycosylase | 1 | 1 | |
A heparin-binding domain | CAPPD, an extracellular domain of amyloid beta A4 protein | 1 | 1 | |
CheY-like | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Rudiment single hybrid motif | Formyltransferase | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | Tudor/PWWP/MBT | 1 | 1 | |
vWA-like | Integrin domains | 1 | 1 | |
Cysteine proteinases | Galactose-binding domain-like | 1 | 1 | |
Nucleotide-binding domain | 4Fe-4S ferredoxins | 1 | 1 | |
MIR domain | EF-hand | 1 | 1 | |
Ubiquitin-like | Cysteine proteinases | 1 | 1 | |
Ribosomal protein S5 domain 2-like | DNA mismatch repair protein MutL | 1 | 1 | |
I/LWEQ domain | alpha-catenin/vinculin-like | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | GroES-like | 1 | 1 | |
PDZ domain-like | Ras GEF | 1 | 1 | |
Sema domain | Immunoglobulin | 1 | 1 | |
EF-hand | GAS2 domain-like | 1 | 1 | |
A DNA-binding domain in eukaryotic transcription factors | Leucine zipper domain | 1 | 1 | |
Elafin-like | Thyroglobulin type-1 domain | 1 | 1 | |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Elongation factor TFIIS domain 2 | 1 | 1 | |
Histone-fold | DBL homology domain (DH-domain) | 1 | 1 | |
Somatomedin B domain | TSP-1 type 1 repeat | 1 | 1 | |
Tricorn protease domain 2 | alpha/beta-Hydrolases | 1 | 1 | |
RING/U-box | R3H domain | 1 | 1 | |
Domain of the SRP/SRP receptor G-proteins | Signal peptide-binding domain | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | ARM repeat | 1 | 1 | |
L domain-like | WD40 repeat-like | 1 | 1 | |
PH domain-like | Gamma-glutamyl cyclotransferase-like | 1 | 1 | |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | L30e-like | 1 | 1 | |
Arginase/deacetylase | Arginase/deacetylase | 1 | 1 | |
E set domains | Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Metallo-dependent hydrolases | 1 | 1 | |
Nucleic acid-binding proteins | SH2 domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Metallo-dependent hydrolases | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 | |
EF-hand | NAD kinase/diacylglycerol kinase-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | ACP-like | 1 | 1 | |
Ribonuclease H-like | Protein kinase-like (PK-like) | 1 | 1 | |
Actin-like ATPase domain | AF1104-like | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Lipocalins | 1 | 1 | |
Heme-dependent peroxidases | Riboflavin synthase domain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | C-terminal domain of ProRS | 1 | 1 | |
Elongation factor TFIIS domain 2 | Zinc beta-ribbon | 1 | 1 | |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | cAMP-binding domain-like | 1 | 1 | |
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | PRTase-like | 1 | 1 | |
Family A G protein-coupled receptor-like | BRCT domain | 1 | 1 | |
RNA-binding domain, RBD | Acid proteases | 1 | 1 | |
vWA-like | DPP6 N-terminal domain-like | 1 | 1 | |
FYVE/PHD zinc finger | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Regulator of G-protein signaling, RGS | 1 | 1 | |
Chromo domain-like | Protein kinase-like (PK-like) | 1 | 1 | |
BRCT domain | DNA/RNA polymerases | 1 | 1 | |
F-box domain | Pectin lyase-like | 1 | 1 | |
PH domain-like | I/LWEQ domain | 1 | 1 | |
Protein kinase-like (PK-like) | FAT domain of focal adhesion kinase | 1 | 1 | |
S15/NS1 RNA-binding domain | C-terminal domain of ProRS | 1 | 1 | |
N-terminal domain of cbl (N-cbl) | SH2 domain | 1 | 1 | |
Putative DNA-binding domain | PheT/TilS domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | KorB DNA-binding domain-like | 1 | 1 | |
Dcp2 domain-like | Nudix | 1 | 1 | |
HAD-like | HAD-like | 1 | 1 | |
POZ domain | Galactose oxidase, central domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
GST C-terminal domain-like | eEF1-gamma domain | 1 | 1 | |
Radical SAM enzymes | MoeA N-terminal region -like | 1 | 1 | |
DNA repair protein MutS, domain II | DNA repair protein MutS, domain III | 1 | 1 | |
ParB/Sulfiredoxin | KorB DNA-binding domain-like | 1 | 1 | |
PurM C-terminal domain-like | Formyltransferase | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | 1 | |
Nqo1 FMN-binding domain-like | Nqo1 middle domain-like | 1 | 1 | |
Protein prenylyltransferase | L domain-like | 1 | 1 | |
WD40 repeat-like | TPR-like | 1 | 1 | |
Regulatory protein AraC | Homeodomain-like | 1 | 1 | |
Chromo domain-like | PH domain-like | 1 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | YbjQ-like | 1 | 1 | |
Nucleic acid-binding proteins | BRCT domain | 1 | 1 | |
TAZ domain | Bromodomain | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | CoA-dependent acyltransferases | 1 | 1 | |
RuvA domain 2-like | DNA-glycosylase | 1 | 1 | |
I/LWEQ domain | I/LWEQ domain | 1 | 1 | |
Second domain of FERM | Gamma-glutamyl cyclotransferase-like | 1 | 1 | |
Cysteine proteinases | HIT/MYND zinc finger-like | 1 | 1 | |
SH3-domain | PLC-like phosphodiesterases | 1 | 1 | |
(Trans)glycosidases | Six-hairpin glycosidases | 1 | 1 | |
Protein kinase-like (PK-like) | RCC1/BLIP-II | 1 | 1 | |
Acetyl-CoA synthetase-like | alpha/beta-Hydrolases | 1 | 1 | |
PreATP-grasp domain | PreATP-grasp domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | DHS-like NAD/FAD-binding domain | 1 | 1 | |
WW domain | PDZ domain-like | 1 | 1 | |
Rhodanese/Cell cycle control phosphatase | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
Immunoglobulin | Soluble quinoprotein glucose dehydrogenase | 1 | 1 | |
mRNA decapping enzyme DcpS N-terminal domain | HIT-like | 1 | 1 | |
Chaperone J-domain | beta-beta-alpha zinc fingers | 1 | 1 | |
(Trans)glycosidases | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
N-terminal domain of cbl (N-cbl) | EF-hand | 1 | 1 | |
RING/U-box | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
S15/NS1 RNA-binding domain | S15/NS1 RNA-binding domain | 1 | 1 | |
Ubiquitin-like | Phase 1 flagellin | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
Chaperone J-domain | E set domains | 1 | 1 | |
Plexin repeat | Integrin beta tail domain | 1 | 1 | |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 1 | 1 | |
Thiolase-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
PH domain-like | POZ domain | 1 | 1 | |
Nucleic acid-binding proteins | eIF2alpha middle domain-like | 1 | 1 | |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | ARM repeat | 1 | 1 | |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | tRNA-binding arm | 1 | 1 | |
GroES-like | ACP-like | 1 | 1 | |
EF-hand | C-terminal domain of PLC-beta | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 | |
"Winged helix" DNA-binding domain | t-snare proteins | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | PreATP-grasp domain | 1 | 1 | |
RNA-binding domain, RBD | SPOC domain-like | 1 | 1 | |
vWA-like | Integrin beta tail domain | 1 | 1 | |
PH domain-like | Phase 1 flagellin | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
ARM repeat | beta-sandwich domain of Sec23/24 | 1 | 1 | |
SAM/Pointed domain | Bet v1-like | 1 | 1 | |
Putative isomerase YbhE | Protein kinase-like (PK-like) | 1 | 1 | |
HMG-box | SET domain | 1 | 1 | |
DNA-glycosylase | Nudix | 1 | 1 | |
Hypothetical protein SAV1430 | Fe-S cluster assembly (FSCA) domain-like | 1 | 1 | |
PAZ domain | dsRNA-binding domain-like | 1 | 1 | |
Thyroglobulin type-1 domain | Serine protease inhibitors | 1 | 1 | |
AN1-like Zinc finger | AN1-like Zinc finger | 1 | 1 | |
DBL homology domain (DH-domain) | Immunoglobulin | 1 | 1 | |
SH3-domain | Immunoglobulin | 1 | 1 | |
Intermediate filament protein, coiled coil region | Myosin rod fragments | 1 | 1 | |
Calcium ATPase, transmembrane domain M | Calcium ATPase, transmembrane domain M | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | PapD-like | 1 | 1 | |
RCC1/BLIP-II | RCC1/BLIP-II | 1 | 1 | |
Histidine-containing phosphotransfer domain, HPT domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
RNA-binding domain, RBD | SET domain | 1 | 1 | |
Immunoglobulin | Calcium-dependent phosphotriesterase | 1 | 1 | |
FnI-like domain | Leech antihemostatic proteins | 1 | 1 | |
A heparin-binding domain | Amyloid beta a4 protein copper binding domain (domain 2) | 1 | 1 | |
MIT domain | Protein kinase-like (PK-like) | 1 | 1 | |
GyrA/ParC C-terminal domain-like | GyrA/ParC C-terminal domain-like | 1 | 1 | |
cAMP-binding domain-like | "Winged helix" DNA-binding domain | 1 | 1 | |
2Fe-2S ferredoxin-like | 4Fe-4S ferredoxins | 1 | 1 | |
Kazal-type serine protease inhibitors | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Mib/herc2 domain-like | Hect, E3 ligase catalytic domain | 1 | 1 | |
Chromo domain-like | BRK domain-like | 1 | 1 | |
GckA/TtuD-like | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
EF-hand | DUSP-like | 1 | 1 | |
(Trans)glycosidases | DNA/RNA polymerases | 1 | 1 | |
PLP-dependent transferases | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
Zinc-binding domain of translation initiation factor 2 beta | ARM repeat | 1 | 1 | |
Trimeric LpxA-like enzymes | ARM repeat | 1 | 1 | |
N-terminal domain of cbl (N-cbl) | RING/U-box | 1 | 1 | |
Concanavalin A-like lectins/glucanases | EF-hand | 1 | 1 | |
Calcium-dependent phosphotriesterase | DPP6 N-terminal domain-like | 1 | 1 | |
Doublecortin (DC) | Doublecortin (DC) | 1 | 1 | |
alpha/beta knot | Nucleic acid-binding proteins | 1 | 1 | |
Second domain of FERM | Second domain of FERM | 1 | 1 | |
YjeF N-terminal domain-like | Ribokinase-like | 1 | 1 | |
SRCR-like | SRCR-like | 1 | 1 | |
HSP20-like chaperones | DNA/RNA polymerases | 1 | 1 | |
Ankyrin repeat | FYVE/PHD zinc finger | 1 | 1 | |
GFP-like | EGF/Laminin | 1 | 1 | |
ENTH/VHS domain | I/LWEQ domain | 1 | 1 | |
Domain of the SRP/SRP receptor G-proteins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Bacterial hemolysins | BSD domain-like | 1 | 1 | |
UBC-like | Protein kinase-like (PK-like) | 1 | 1 | |
Ras GEF | PLC-like phosphodiesterases | 1 | 1 | |
PreATP-grasp domain | post-HMGL domain-like | 1 | 1 | |
Alpha subunit of glutamate synthase, C-terminal domain | FAD/NAD(P)-binding domain | 1 | 1 | |
Cupredoxins | Cupredoxins | 1 | 1 | |
UBA-like | Peptidyl-tRNA hydrolase II | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | eEF-1beta-like | 1 | 1 | |
alpha/beta-Hydrolases | SET domain | 1 | 1 | |
SET domain | WW domain | 1 | 1 | |
Trypsin-like serine proteases | Trypsin-like serine proteases | 1 | 1 | |
CRAL/TRIO domain | PapD-like | 1 | 1 | |
beta-beta-alpha zinc fingers | Cysteine proteinases | 1 | 1 | |
Tex N-terminal region-like | SH2 domain | 1 | 1 | |
Serpins | Nucleotide-diphospho-sugar transferases | 1 | 1 | |
Urocanase | Urocanase | 1 | 1 | |
SMAD/FHA domain | PH domain-like | 1 | 1 | |
DNase I-like | RNA-binding domain, RBD | 1 | 1 | |
Protein kinase-like (PK-like) | HCP-like | 1 | 1 | |
BRCT domain | Lesion bypass DNA polymerase (Y-family), little finger domain | 1 | 1 | |
PYP-like sensor domain (PAS domain) | cAMP-binding domain-like | 1 | 1 | |
IP3 receptor type 1 binding core, domain 2 | EF-hand | 1 | 1 | |
MIT domain | Cysteine proteinases | 1 | 1 | |
Thioredoxin-like | Ubiquitin-like | 1 | 1 | |
Acyl-CoA binding protein | ClpP/crotonase | 1 | 1 | |
Plexin repeat | vWA-like | 1 | 1 | |
Leukotriene A4 hydrolase N-terminal domain | Leukotriene A4 hydrolase N-terminal domain | 1 | 1 | |
Chitinase insertion domain | Invertebrate chitin-binding proteins | 1 | 1 | |
BAR/IMD domain-like | RING/U-box | 1 | 1 | |
post-HMGL domain-like | Single hybrid motif | 1 | 1 | |
Homocysteine S-methyltransferase | Dihydropteroate synthetase-like | 1 | 1 | |
Nucleotide-binding domain | Nucleotide-binding domain | 1 | 1 | |
Ubiquitin-like | BAG domain | 1 | 1 | |
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | 1 | 1 | |
PLP-dependent transferases | PLP-dependent transferases | 1 | 1 | |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | Translational machinery components | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Molybdopterin synthase subunit MoaE | 1 | 1 | |
DNA repair protein MutS, domain II | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Seven-hairpin glycosidases | PA domain | 1 | 1 | |
Galactose oxidase, central domain | Kelch motif | 1 | 1 | |
Cysteine-rich domain | SH3-domain | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | Clavaminate synthase-like | 1 | 1 | |
Galactose-binding domain-like | Mib/herc2 domain-like | 1 | 1 | |
Adhesin YadA, collagen-binding domain | Pili subunits | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Restriction endonuclease-like | RuvA domain 2-like | 1 | 1 | |
Concanavalin A-like lectins/glucanases | ARM repeat | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | SAM/Pointed domain | 1 | 1 | |
YccV-like | ApaG-like | 1 | 1 | |
Cytochrome c | Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor | 1 | 1 | |
GTPase activation domain, GAP | Bet v1-like | 1 | 1 | |
Galactose-binding domain-like | Concanavalin A-like lectins/glucanases | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Protein kinase-like (PK-like) | 1 | 1 | |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | 1 | |
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | Protein kinase-like (PK-like) | 1 | 1 | |
PP2C-like | Protein kinase-like (PK-like) | 1 | 1 | |
PEBP-like | PEBP-like | 1 | 1 | |
SET domain | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
UBA-like | DNase I-like | 1 | 1 | |
DNA-binding domain | Bromodomain | 1 | 1 | |
Calcium-dependent phosphotriesterase | vWA-like | 1 | 1 | |
YWTD domain | Fibronectin type III | 1 | 1 | |
SMAD/FHA domain | Protein kinase-like (PK-like) | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RNase III domain-like | 1 | 1 | |
Homeodomain-like | Multidrug efflux transporter AcrB transmembrane domain | 1 | 1 | |
Ricin B-like lectins | Ricin B-like lectins | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
PUA domain-like | eIF1-like | 1 | 1 | |
POZ domain | FYVE/PHD zinc finger | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | "Winged helix" DNA-binding domain | 1 | 1 | |
UBA-like | UBA-like | 1 | 1 | |
Trypsin-like serine proteases | RING/U-box | 1 | 1 | |
Concanavalin A-like lectins/glucanases | C-type lectin-like | 1 | 1 | |
DNA-glycosylase | DNA-glycosylase | 1 | 1 | |
FabD/lysophospholipase-like | FabD/lysophospholipase-like | 1 | 1 | |
GroEL apical domain-like | SAICAR synthase-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | alpha/beta-Hydrolases | 1 | 1 | |
Methionine synthase domain | Methionine synthase activation domain-like | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
PH domain-like | Bet v1-like | 1 | 1 | |
Rudiment single hybrid motif | post-HMGL domain-like | 1 | 1 | |
Rap/Ran-GAP | PDZ domain-like | 1 | 1 | |
Rap/Ran-GAP | Rap/Ran-GAP | 1 | 1 | |
Actin depolymerizing proteins | VHP, Villin headpiece domain | 1 | 1 | |
Ubiquitin-like | ARM repeat | 1 | 1 | |
Zn-dependent exopeptidases | "Winged helix" DNA-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | ParB/Sulfiredoxin | 1 | 1 | |
TAZ domain | RING/U-box | 1 | 1 | |
Periplasmic binding protein-like I | A DNA-binding domain in eukaryotic transcription factors | 1 | 1 | |
ATP-dependent DNA ligase DNA-binding domain | Nucleic acid-binding proteins | 1 | 1 | |
ENTH/VHS domain | FYVE/PHD zinc finger | 1 | 1 | |
DAK1/DegV-like | DhaL-like | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Cadherin-like | 1 | 1 | |
GAF domain-like | alpha/beta knot | 1 | 1 | |
PH domain-like | A middle domain of Talin 1 | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | Formate/glycerate dehydrogenase catalytic domain-like | 1 | 1 | |
RNA-binding domain, RBD | Surp module (SWAP domain) | 1 | 1 | |
Surp module (SWAP domain) | Ubiquitin-like | 1 | 1 | |
Heme-dependent peroxidases | EF-hand | 1 | 1 | |
ERH-like | "Winged helix" DNA-binding domain | 1 | 1 | |
EGF/Laminin | Hormone receptor domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Single hybrid motif | 1 | 1 | |
Periplasmic binding protein-like I | Leucine zipper domain | 1 | 1 | |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 1 | 1 | |
Immunoglobulin | Concanavalin A-like lectins/glucanases | 1 | 1 | |
RNI-like | PapD-like | 1 | 1 | |
CAD & PB1 domains | PDZ domain-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
Fibronectin type III | vWA-like | 1 | 1 | |
BAR/IMD domain-like | ArfGap/RecO-like zinc finger | 1 | 1 | |
Fibronectin type III | Soluble quinoprotein glucose dehydrogenase | 1 | 1 | |
beta-beta-alpha zinc fingers | Multiheme cytochromes | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | post-HMGL domain-like | 1 | 1 | |
Second domain of FERM | Phase 1 flagellin | 1 | 1 | |
EndoU-like | EndoU-like | 1 | 1 | |
L domain-like | ARM repeat | 1 | 1 | |
Formin homology 2 domain (FH2 domain) | Spermadhesin, CUB domain | 1 | 1 | |
Retrovirus zinc finger-like domains | RING/U-box | 1 | 1 | |
EF-hand | Mannose 6-phosphate receptor domain | 1 | 1 | |
RING/U-box | E set domains | 1 | 1 | |
Calponin-homology domain, CH-domain | Nicotinate/Quinolinate PRTase N-terminal domain-like | 1 | 1 | |
Actin depolymerizing proteins | SH3-domain | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
BAR/IMD domain-like | Cysteine-rich domain | 1 | 1 | |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 | |
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | DNA breaking-rejoining enzymes | 1 | 1 | |
Family A G protein-coupled receptor-like | Pseudouridine synthase | 1 | 1 | |
p53-like transcription factors | Nucleotide-diphospho-sugar transferases | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | GroES-like | 1 | 1 | |
FYVE/PHD zinc finger | Rabenosyn-5 Rab-binding domain-like | 1 | 1 | |
PreATP-grasp domain | Methylglyoxal synthase-like | 1 | 1 | |
4Fe-4S ferredoxins | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
ARM repeat | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 1 | 1 | |
Acyl-CoA dehydrogenase C-terminal domain-like | Metallo-hydrolase/oxidoreductase | 1 | 1 | |
Frizzled cysteine-rich domain | TIMP-like | 1 | 1 | |
Class I glutamine amidotransferase-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Zn-dependent exopeptidases | Creatinase/aminopeptidase | 1 | 1 | |
MAST3 pre-PK domain-like | Protein kinase-like (PK-like) | 1 | 1 | |
PUA domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 1 | 1 | |
DsbC/DsbG N-terminal domain-like | Thioredoxin-like | 1 | 1 | |
RuvA domain 2-like | SH2 domain | 1 | 1 | |
alpha/beta-Hydrolases | Nuclear receptor ligand-binding domain | 1 | 1 | |
LysM domain | Periplasmic binding protein-like II | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase domain | 1 | 1 | |
EGF/Laminin | DPP6 N-terminal domain-like | 1 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | UBA-like | 1 | 1 | |
Ankyrin repeat | LEM domain | 1 | 1 | |
PH domain-like | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
WW domain | RING/U-box | 1 | 1 | |
Ribonuclease PH domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
Doublecortin (DC) | Protein kinase-like (PK-like) | 1 | 1 | |
PLC-like phosphodiesterases | Ubiquitin-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Arp2/3 complex subunits | 1 | 1 | |
EGF/Laminin | Fibronectin type III | 1 | 1 | |
"Winged helix" DNA-binding domain | RNA-binding domain, RBD | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | ATP-dependent DNA ligase DNA-binding domain | 1 | 1 | |
alpha/beta-Hydrolases | Ubiquitin-like | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Metallo-dependent hydrolases | 1 | 1 | |
Ankyrin repeat | L domain-like | 1 | 1 | |
PreATP-grasp domain | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
A middle domain of Talin 1 | alpha-catenin/vinculin-like | 1 | 1 | |
Ubiquitin-like | Gamma-glutamyl cyclotransferase-like | 1 | 1 | |
FMN-linked oxidoreductases | dsRNA-binding domain-like | 1 | 1 | |
SAICAR synthase-like | N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 1 | 1 | |
Cystatin/monellin | Cysteine proteinases | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Formyltransferase | 1 | 1 | |
"Winged helix" DNA-binding domain | occludin/ELL-like | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | Methionine synthase activation domain-like | 1 | 1 | |
PX domain | PH domain-like | 1 | 1 | |
Amyloid beta a4 protein copper binding domain (domain 2) | CAPPD, an extracellular domain of amyloid beta A4 protein | 1 | 1 | |
Acyl-CoA binding protein | Ankyrin repeat | 1 | 1 | |
Chaperone J-domain | Sec63 N-terminal domain-like | 1 | 1 | |
Calponin-homology domain, CH-domain | SH2 domain | 1 | 1 | |
NagB/RpiA/CoA transferase-like | Isocitrate/Isopropylmalate dehydrogenase-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | CoA-dependent acyltransferases | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 1 | 1 | |
Ypt/Rab-GAP domain of gyp1p | EF-hand | 1 | 1 | |
Glutamine synthetase, N-terminal domain | (Trans)glycosidases | 1 | 1 | |
MurD-like peptide ligases, catalytic domain | MurD-like peptide ligases, peptide-binding domain | 1 | 1 | |
WW domain | PIN domain-like | 1 | 1 | |
TSP-1 type 1 repeat | alpha/beta-Hydrolases | 1 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | PX domain | 1 | 1 | |
NAD kinase/diacylglycerol kinase-like | NAD kinase/diacylglycerol kinase-like | 1 | 1 | |
HIT-like | HIT-like | 1 | 1 | |
ACT-like | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 1 | 1 | |
LysM domain | Chitinase insertion domain | 1 | 1 | |
Class I glutamine amidotransferase-like | Methylglyoxal synthase-like | 1 | 1 | |
Class II aaRS ABD-related | C-terminal domain of ProRS | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Metallo-dependent phosphatases | 1 | 1 | |
PreATP-grasp domain | ClpP/crotonase | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | SH3-domain | 1 | 1 | |
alpha-helical ferredoxin | FAD/NAD(P)-binding domain | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
SMAD/FHA domain | FYVE/PHD zinc finger | 1 | 1 | |
FabD/lysophospholipase-like | Acetyl-CoA synthetase-like | 1 | 1 | |
Ankyrin repeat | ADP-ribosylation | 1 | 1 | |
Ankyrin repeat | Mib/herc2 domain-like | 1 | 1 | |
RING/U-box | Nucleotidylyl transferase | 1 | 1 | |
E2F-DP heterodimerization region | t-snare proteins | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Methylglyoxal synthase-like | 1 | 1 | |
B-box zinc-binding domain | Fibronectin type III | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | Riboflavin synthase domain-like | 1 | 1 | |
Activator of Hsp90 ATPase, Aha1 | Bet v1-like | 1 | 1 | |
Hairpin loop containing domain-like | TSP-1 type 1 repeat | 1 | 1 | |
Plexin repeat | EGF/Laminin | 1 | 1 | |
Lipocalins | Lipocalins | 1 | 1 | |
Protein kinase-like (PK-like) | Acyl-CoA dehydrogenase NM domain-like | 1 | 1 | |
DNA/RNA polymerases | Homeodomain-like | 1 | 1 | |
Kix domain of CBP (creb binding protein) | RING/U-box | 1 | 1 | |
Tim10-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
WW domain | EF-hand | 1 | 1 | |
Ankyrin repeat | WGR domain-like | 1 | 1 | |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 | |
YbiA-like | YbiA-like | 1 | 1 | |
PYP-like sensor domain (PAS domain) | HD-domain/PDEase-like | 1 | 1 | |
Galactose-binding domain-like | Fibronectin type III | 1 | 1 | |
Nucleic acid-binding proteins | Retrovirus zinc finger-like domains | 1 | 1 | |
Spermadhesin, CUB domain | Galactose oxidase, central domain | 1 | 1 | |
PH domain-like | FAT domain of focal adhesion kinase | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | SMR domain-like | 1 | 1 | |
Clavaminate synthase-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Eea1 homodimerisation domain | FYVE/PHD zinc finger | 1 | 1 | |
FAD-linked reductases, C-terminal domain | Folate-binding domain | 1 | 1 | |
ACT-like | Formyltransferase | 1 | 1 | |
Ribosomal protein S5 domain 2-like | HIT/MYND zinc finger-like | 1 | 1 | |
Aminopeptidase/glucanase lid domain | Zn-dependent exopeptidases | 1 | 1 | |
MoeA N-terminal region -like | MoeA C-terminal domain-like | 1 | 1 | |
Thioredoxin-like | Phosphoglycerate mutase-like | 1 | 1 | |
Soluble quinoprotein glucose dehydrogenase | DPP6 N-terminal domain-like | 1 | 1 | |
GTPase activation domain, GAP | RGC domain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 1 | 1 | |
HR1 repeat | Protein kinase-like (PK-like) | 1 | 1 | |
Eukaryotic RPB5 N-terminal domain | RPB5-like RNA polymerase subunit | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Protein kinase-like (PK-like) | 1 | 1 | |
Invertebrate chitin-binding proteins | BPTI-like | 1 | 1 | |
Calponin-homology domain, CH-domain | Calponin-homology domain, CH-domain | 1 | 1 | |
Cysteine proteinases | Chromo domain-like | 1 | 1 | |
Terpenoid cyclases/Protein prenyltransferases | Terpenoid cyclases/Protein prenyltransferases | 1 | 1 | |
Calponin-homology domain, CH-domain | RING/U-box | 1 | 1 | |
beta-sandwich domain of Sec23/24 | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
F-box domain | Galactose-binding domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Rhomboid-like | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | RING/U-box | 1 | 1 | |
Glycosyl hydrolase domain | DNase I-like | 1 | 1 | |
HAD-like | Acyl-CoA dehydrogenase C-terminal domain-like | 1 | 1 | |
POZ domain | WD40 repeat-like | 1 | 1 | |
Dom34/Pelota N-terminal domain-like | Translational machinery components | 1 | 1 | |
Protein kinase-like (PK-like) | Class II aaRS and biotin synthetases | 1 | 1 | |
Nucleic acid-binding proteins | GAD domain-like | 1 | 1 | |
Spermadhesin, CUB domain | Kelch motif | 1 | 1 | |
Plakin repeat | Plakin repeat | 1 | 1 | |
DBL homology domain (DH-domain) | Fibronectin type III | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | AN1-like Zinc finger | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Phosphoglycerate mutase-like | 1 | 1 | |
TRAF domain-like | Cysteine proteinases | 1 | 1 | |
alpha/beta-Hydrolases | Sensory domain-like | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | DNA-glycosylase | 1 | 1 | |
Histidine-containing phosphotransfer domain, HPT domain | Histidine-containing phosphotransfer domain, HPT domain | 1 | 1 | |
Cap-Gly domain | Cysteine proteinases | 1 | 1 | |
Second domain of FERM | I/LWEQ domain | 1 | 1 | |
Growth factor receptor domain | Ankyrin repeat | 1 | 1 | |
Metallo-hydrolase/oxidoreductase | Metallo-hydrolase/oxidoreductase | 1 | 1 | |
Fibronectin type III | DPP6 N-terminal domain-like | 1 | 1 | |
SMAD/FHA domain | dsRNA-binding domain-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
Tsx-like channel | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
WWE domain | WWE domain | 1 | 1 | |
TPR-like | Ankyrin repeat | 1 | 1 | |
ENTH/VHS domain | SH3-domain | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Nucleic acid-binding proteins | 1 | 1 | |
Thioredoxin-like | Six-hairpin glycosidases | 1 | 1 | |
EGF/Laminin | Integrin beta tail domain | 1 | 1 | |
Leucine zipper domain | Leucine zipper domain | 1 | 1 | |
Kix domain of CBP (creb binding protein) | Bromodomain | 1 | 1 | |
PH domain-like | Cullin repeat-like | 1 | 1 | |
L domain-like | RING/U-box | 1 | 1 | |
Homocysteine S-methyltransferase | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
RNA-binding domain, RBD | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Ubiquitin-like | RING/U-box | 1 | 1 | |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 1 | 1 | |
SRCR-like | Pectin lyase-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
SH3-domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
GST C-terminal domain-like | eEF-1beta-like | 1 | 1 | |
4Fe-4S ferredoxins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Ankyrin repeat | (Trans)glycosidases | 1 | 1 | |
Homeodomain-like | Thioredoxin-like | 1 | 1 | |
FAD/NAD(P)-binding domain | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Ribonuclease PH domain 2-like | Ribonuclease PH domain 2-like | 1 | 1 | |
Nucleotidylyl transferase | An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 1 | 1 | |
DNA/RNA polymerases | DNA/RNA polymerases | 1 | 1 | |
L domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
C-type lectin-like | Fibrinogen C-terminal domain-like | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
Cyclophilin-like | Cyclophilin-like | 1 | 1 | |
SH2 domain | PLC-like phosphodiesterases | 1 | 1 | |
WD40 repeat-like | Ribonuclease H-like | 1 | 1 | |
PLP-dependent transferases | PK beta-barrel domain-like | 1 | 1 | |
Thyroglobulin type-1 domain | Cu,Zn superoxide dismutase-like | 1 | 1 | |
PreATP-grasp domain | Metallo-dependent hydrolases | 1 | 1 | |
BAR/IMD domain-like | Ankyrin repeat | 1 | 1 | |
ARM repeat | DNA breaking-rejoining enzymes | 1 | 1 | |
Pseudouridine synthase | PUA domain-like | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | Retrovirus zinc finger-like domains | 1 | 1 | |
PDZ domain-like | Cysteine-rich domain | 1 | 1 | |
Spermadhesin, CUB domain | Lipocalins | 1 | 1 | |
Leech antihemostatic proteins | Leech antihemostatic proteins | 1 | 1 | |
Ubiquitin-like | AN1-like Zinc finger | 1 | 1 | |
E set domains | Ankyrin repeat | 1 | 1 | |
Quinoprotein alcohol dehydrogenase-like | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Cytochrome P450 | 1 | 1 | |
RNA-binding domain, RBD | RNI-like | 1 | 1 | |
RCC1/BLIP-II | Galactose-binding domain-like | 1 | 1 | |
Acyl-CoA binding protein | Supernatant protein factor (SPF), C-terminal domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Acetyl-CoA synthetase-like | 1 | 1 | |
Phosphoglycerate mutase-like | HAD-like | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | MoeA C-terminal domain-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Phosphoglycerate mutase-like | 1 | 1 | |
Serine protease inhibitors | Fibrinogen C-terminal domain-like | 1 | 1 | |
Staphylococcal nuclease | Staphylococcal nuclease | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | ArfGap/RecO-like zinc finger | 1 | 1 | |
L9 N-domain-like | L9 N-domain-like | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Metallo-dependent hydrolases | 1 | 1 | |
alpha-ketoacid dehydrogenase kinase, N-terminal domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Ribonuclease H-like | RING/U-box | 1 | 1 | |
Dimeric alpha+beta barrel | Dimeric alpha+beta barrel | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | DHS-like NAD/FAD-binding domain | 1 | 1 | |
FYVE/PHD zinc finger | PDZ domain-like | 1 | 1 | |
Nucleotidylyl transferase | tRNA-binding arm | 1 | 1 | |
NusB-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
FabD/lysophospholipase-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | DNA mismatch repair protein MutL | 1 | 1 | |
CBS-domain pair | Inosine monophosphate dehydrogenase (IMPDH) | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Cysteine-rich domain | 1 | 1 | |
Ankyrin repeat | Domain of poly(ADP-ribose) polymerase | 1 | 1 | |
RNA-binding domain, RBD | MAL13P1.257-like | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 | |
FAD-linked reductases, C-terminal domain | 4Fe-4S ferredoxins | 1 | 1 | |
EGF/Laminin | TIMP-like | 1 | 1 | |
Serine protease inhibitors | CBD9-like | 1 | 1 | |
TGS-like | Class II aaRS ABD-related | 1 | 1 | |
Terpenoid cyclases/Protein prenyltransferases | Alpha-macroglobulin receptor domain | 1 | 1 | |
Immunoglobulin | Kringle-like | 1 | 1 | |
Family A G protein-coupled receptor-like | DNA/RNA polymerases | 1 | 1 | |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
RUN domain-like | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | 1 | |
LysM domain | (Trans)glycosidases | 1 | 1 | |
UBC-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Thiolase-like | alpha/beta-Hydrolases | 1 | 1 | |
HAD-like | Protein kinase-like (PK-like) | 1 | 1 | |
Metallo-dependent phosphatases | EF-hand | 1 | 1 | |
ALDH-like | Rudiment single hybrid motif | 1 | 1 | |
RING/U-box | RNA-binding domain, RBD | 1 | 1 | |
Actin depolymerizing proteins | C-terminal, gelsolin-like domain of Sec23/24 | 1 | 1 | |
Tropomyosin | SAM/Pointed domain | 1 | 1 | |
PH domain-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
FAD-linked reductases, C-terminal domain | Aminomethyltransferase beta-barrel domain | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | L domain-like | 1 | 1 | |
POZ domain | Ankyrin repeat | 1 | 1 | |
Calcium-dependent phosphotriesterase | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Ribosomal protein L25-like | S15/NS1 RNA-binding domain | 1 | 1 | |
Moesin tail domain | Gamma-glutamyl cyclotransferase-like | 1 | 1 | |
PDZ domain-like | PX domain | 1 | 1 | |
Subtilisin-like | Growth factor receptor domain | 1 | 1 | |
Class I glutamine amidotransferase-like | PreATP-grasp domain | 1 | 1 | |
Doublecortin (DC) | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | 1 | |
"Winged helix" DNA-binding domain | PLP-dependent transferases | 1 | 1 | |
EF-hand | Rhomboid-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 | |
Histone-fold | PH domain-like | 1 | 1 | |
L9 N-domain-like | Ribonuclease H-like | 1 | 1 | |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 1 | 1 | |
FYVE/PHD zinc finger | Chromo domain-like | 1 | 1 | |
Methylglyoxal synthase-like | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
NAD-binding domain of HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | 1 | 1 | |
Sema domain | Protein kinase-like (PK-like) | 1 | 1 | |
WD40 repeat-like | Soluble quinoprotein glucose dehydrogenase | 1 | 1 | |
Family A G protein-coupled receptor-like | Ankyrin repeat | 1 | 1 | |
LDL receptor-like module | Concanavalin A-like lectins/glucanases | 1 | 1 | |
PDZ domain-like | ARM repeat | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | alpha/beta-Hydrolases | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | alpha/beta-Hydrolases | 1 | 1 | |
FAD/NAD(P)-binding domain | HI0933 insert domain-like | 1 | 1 | |
Family A G protein-coupled receptor-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Phase 1 flagellin | alpha-catenin/vinculin-like | 1 | 1 | |
E set domains | Glycosyl hydrolase domain | 1 | 1 | |
Thiolase-like | CoA-dependent acyltransferases | 1 | 1 | |
t-snare proteins | DNA/RNA polymerases | 1 | 1 | |
Second domain of FERM | Protein kinase-like (PK-like) | 1 | 1 | |
WD40 repeat-like | DPP6 N-terminal domain-like | 1 | 1 | |
ARM repeat | Chaperone J-domain | 1 | 1 | |
FYVE/PHD zinc finger | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Calponin-homology domain, CH-domain | Plakin repeat | 1 | 1 | |
EF-hand | Cysteine proteinases | 1 | 1 | |
PreATP-grasp domain | PurM C-terminal domain-like | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | PapD-like | 1 | 1 | |
DNA/RNA polymerases | MFS general substrate transporter | 1 | 1 | |
Calponin-homology domain, CH-domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
DNA-binding domain | SET domain | 1 | 1 | |
Ribosomal protein L6 | Ribosomal protein L6 | 1 | 1 | |
PH domain-like | C-terminal domain of PLC-beta | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
SH2 domain | GTPase activation domain, GAP | 1 | 1 | |
Heat shock protein 70kD (HSP70), C-terminal subdomain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
PUG domain-like | Ubiquitin-like | 1 | 1 | |
Second domain of FERM | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
Viral glycoprotein ectodomain-like | Protein kinase-like (PK-like) | 1 | 1 | |
LDL receptor-like module | Mannose 6-phosphate receptor domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Methylglyoxal synthase-like | 1 | 1 | |
RING/U-box | Fibronectin type III | 1 | 1 | |
ALDH-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
Sigma2 domain of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 1 | 1 | |
PH0987 N-terminal domain-like | Cyclophilin-like | 1 | 1 | |
TSP-1 type 1 repeat | DEATH domain | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
PYP-like sensor domain (PAS domain) | Voltage-gated potassium channels | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
vWA-like | Cysteine-rich domain | 1 | 1 | |
F-box domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Methionine synthase domain | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
Carbamate kinase-like | ALDH-like | 1 | 1 | |
ARM repeat | DNA/RNA polymerases | 1 | 1 | |
Immunoglobulin | DPP6 N-terminal domain-like | 1 | 1 | |
Soluble quinoprotein glucose dehydrogenase | Calcium-dependent phosphotriesterase | 1 | 1 | |
Thyroglobulin type-1 domain | Leech antihemostatic proteins | 1 | 1 | |
Galactose-binding domain-like | RING/U-box | 1 | 1 | |
SH3-domain | Second domain of FERM | 1 | 1 | |
UBC-like | RING/U-box | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
Voltage-gated potassium channels | RNA-binding domain, RBD | 1 | 1 | |
C-type lectin-like | Family A G protein-coupled receptor-like | 1 | 1 | |
RNA-binding domain, RBD | Ribonuclease H-like | 1 | 1 | |
L domain-like | Ubiquitin-like | 1 | 1 | |
Protein kinase-like (PK-like) | NTF2-like | 1 | 1 | |
PHP domain-like | AF1531-like | 1 | 1 | |
PUA domain-like | Nucleotidylyl transferase | 1 | 1 | |
dUTPase-like | dUTPase-like | 1 | 1 | |
Growth factor receptor domain | Glycoside hydrolase/deacetylase | 1 | 1 | |
Dom34/Pelota N-terminal domain-like | L30e-like | 1 | 1 | |
SAP domain | RNA-binding domain, RBD | 1 | 1 | |
Ras GEF | EF-hand | 1 | 1 | |
EGF/Laminin | Fibrinogen C-terminal domain-like | 1 | 1 | |
ClpP/crotonase | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
DBL homology domain (DH-domain) | BAR/IMD domain-like | 1 | 1 | |
Translation proteins | Translation proteins | 1 | 1 | |
PLP-dependent transferases | MOSC N-terminal domain-like | 1 | 1 | |
Zinc beta-ribbon | Zinc beta-ribbon | 1 | 1 | |
Second domain of FERM | A middle domain of Talin 1 | 1 | 1 | |
SH3-domain | RUN domain-like | 1 | 1 | |
Calponin-homology domain, CH-domain | RGC domain-like | 1 | 1 | |
CCCH zinc finger | Retrovirus zinc finger-like domains | 1 | 1 | |
SH3-domain | ARM repeat | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | PurM C-terminal domain-like | 1 | 1 | |
A middle domain of Talin 1 | I/LWEQ domain | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | Sensory domain-like | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Methylglyoxal synthase-like | 1 | 1 | |
FabD/lysophospholipase-like | GroES-like | 1 | 1 | |
PAZ domain | RNase III domain-like | 1 | 1 | |
ERH-like | PDZ domain-like | 1 | 1 | |
SMAD/FHA domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | VHP, Villin headpiece domain | 1 | 1 | |
Putative DNA-binding domain | Putative DNA-binding domain | 1 | 1 | |
Nucleotide-binding domain | FAD/NAD(P)-binding domain | 1 | 1 | |
Nqo1 middle domain-like | Nqo1C-terminal domain-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
Ubiquitin-like | Zn-binding ribosomal proteins | 1 | 1 | |
Regulator of G-protein signaling, RGS | Cysteine-rich domain | 1 | 1 | |
WD40 repeat-like | Cyclophilin-like | 1 | 1 | |
IP3 receptor type 1 binding core, domain 2 | ARM repeat | 1 | 1 | |
PDZ domain-like | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
FYVE/PHD zinc finger | HMG-box | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | ARM repeat | 1 | 1 | |
ARM repeat | Rap/Ran-GAP | 1 | 1 | |
Metallo-dependent hydrolases | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
DNase I-like | GTPase activation domain, GAP | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
FAD/NAD(P)-binding domain | 4Fe-4S ferredoxins | 1 | 1 | |
DBL homology domain (DH-domain) | SH2 domain | 1 | 1 | |
Pectin lyase-like | Cadherin-like | 1 | 1 | |
PH domain-like | alpha-catenin/vinculin-like | 1 | 1 | |
MetI-like | MetI-like | 1 | 1 | |
Tropomyosin | TPR-like | 1 | 1 | |
Soluble quinoprotein glucose dehydrogenase | Soluble quinoprotein glucose dehydrogenase | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | HAD-like | 1 | 1 | |
ALDH-like | Aldolase | 1 | 1 | |
Nucleotidyltransferase | PapD-like | 1 | 1 | |
MIR domain | ARM repeat | 1 | 1 | |
Heme-dependent peroxidases | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
EF-hand | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
HR1 repeat | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
PX domain | Phospholipase D/nuclease | 1 | 1 | |
ClpP/crotonase | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 | |
L domain-like | Actin depolymerizing proteins | 1 | 1 | |
Integrin domains | EGF/Laminin | 1 | 1 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
Tetraspanin | Tetraspanin | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Serine metabolism enzymes domain | 1 | 1 | |
L27 domain | SH3-domain | 1 | 1 | |
Ubiquitin-like | XPC-binding domain | 1 | 1 | |
PreATP-grasp domain | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
RuvA domain 2-like | BRCT domain | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Hormone receptor domain | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Ankyrin repeat | B-box zinc-binding domain | 1 | 1 | |
Protease propeptides/inhibitors | Growth factor receptor domain | 1 | 1 | |
Serine protease inhibitors | Cu,Zn superoxide dismutase-like | 1 | 1 | |
PH domain-like | "Winged helix" DNA-binding domain | 1 | 1 | |
G protein-binding domain | FYVE/PHD zinc finger | 1 | 1 | |
B-box zinc-binding domain | B-box zinc-binding domain | 1 | 1 | |
Calponin-homology domain, CH-domain | PRC-barrel domain | 1 | 1 | |
Glutaminase/Asparaginase | Ankyrin repeat | 1 | 1 | |
Serpins | Serpins | 1 | 1 | |
ARM repeat | PAZ domain | 1 | 1 | |
Protein kinase-like (PK-like) | Ypt/Rab-GAP domain of gyp1p | 1 | 1 | |
GMP synthetase C-terminal dimerisation domain | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Spectrin repeat | RING/U-box | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Nuclear receptor ligand-binding domain | 1 | 1 | |
BSD domain-like | BSD domain-like | 1 | 1 | |
alpha-helical ferredoxin | 4Fe-4S ferredoxins | 1 | 1 | |
Class I glutamine amidotransferase-like | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
Ribonuclease H-like | SH2 domain | 1 | 1 | |
CoA-dependent acyltransferases | alpha/beta-Hydrolases | 1 | 1 | |
Spermadhesin, CUB domain | Complement control module/SCR domain | 1 | 1 | |
ARID-like | ARM repeat | 1 | 1 | |
"Winged helix" DNA-binding domain | Protein kinase-like (PK-like) | 1 | 1 | |
Chromo domain-like | RUN domain-like | 1 | 1 | |
B-box zinc-binding domain | E set domains | 1 | 1 | |
E set domains | Nicotinate/Quinolinate PRTase N-terminal domain-like | 1 | 1 | |
RUN domain-like | PH domain-like | 1 | 1 | |
PLC-like phosphodiesterases | C-terminal domain of PLC-beta | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
PX domain | PX domain | 1 | 1 | |
Calponin-homology domain, CH-domain | GTPase activation domain, GAP | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | RuvA domain 2-like | 1 | 1 | |
Growth factor receptor domain | Notch domain | 1 | 1 | |
Macro domain-like | Zn-dependent exopeptidases | 1 | 1 | |
Composite domain of metallo-dependent hydrolases | Aspartate/ornithine carbamoyltransferase | 1 | 1 | |
RING/U-box | Nuclear receptor ligand-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | PAZ domain | 1 | 1 | |
p53-like transcription factors | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
"Winged helix" DNA-binding domain | GntR ligand-binding domain-like | 1 | 1 | |
RAP domain-like | RAP domain-like | 1 | 1 | |
Staphylococcal nuclease | Tudor/PWWP/MBT | 1 | 1 | |
PurM N-terminal domain-like | PurM N-terminal domain-like | 1 | 1 | |