Domain combination pairs in Capsaspora owczarzaki ATCC 30864

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1908 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	89	35
L domain-like	Growth factor receptor domain	84	24
RNI-like	Protein kinase-like (PK-like)	62	16
Growth factor receptor domain	Protein kinase-like (PK-like)	41	22
L domain-like	Protein kinase-like (PK-like)	40	17
L domain-like	L domain-like	39	26
RNI-like	RNI-like	31	13
ARM repeat	ARM repeat	30	22
Actin-like ATPase domain	Actin-like ATPase domain	28	13
TPR-like	TPR-like	27	16
Ankyrin repeat	Ankyrin repeat	25	14
PH domain-like	PH domain-like	25	25
DBL homology domain (DH-domain)	PH domain-like	24	20
Growth factor receptor domain	Growth factor receptor domain	22	21
Calcium ATPase, transduction domain A	HAD-like	20	7
BAR/IMD domain-like	SH3-domain	20	15
HAD-like	Calcium ATPase, transmembrane domain M	19	6
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	19	6
PH domain-like	SH3-domain	19	19
Protein kinase-like (PK-like)	ARM repeat	18	17
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	18	5
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	18	5
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	18	11
RNA-binding domain, RBD	RNA-binding domain, RBD	18	13
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	18	5
GroES-like	NAD(P)-binding Rossmann-fold domains	18	5
CalX-like	CalX-like	18	13
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	18	17
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	18	8
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	17	9
Protein kinase-like (PK-like)	RING/U-box	17	10
RNI-like	P-loop containing nucleoside triphosphate hydrolases	17	6
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	16	8
Complement control module/SCR domain	Complement control module/SCR domain	16	11
Growth factor receptor domain	CalX-like	16	11
SH3-domain	SH3-domain	15	15
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	15	8
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	15	7
PH domain-like	Protein kinase-like (PK-like)	15	15
WW domain	WW domain	15	14
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	14	13
F-box domain	WD40 repeat-like	14	8
Pectin lyase-like	Pectin lyase-like	14	8
EGF/Laminin	Growth factor receptor domain	14	9
Ubiquitin-like	PH domain-like	14	14
EGF/Laminin	CalX-like	13	8
WD40 repeat-like	WD40 repeat-like	13	9
RNI-like	RING/U-box	12	5
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	12	6
ARM repeat	WD40 repeat-like	12	12
PH domain-like	GTPase activation domain, GAP	12	11
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	12	10
Cysteine-rich domain	C2 domain (Calcium/lipid-binding domain, CaLB)	12	10
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	11	8
Cyclin-like	Cyclin-like	11	7
Complement control module/SCR domain	Protein kinase-like (PK-like)	11	7
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	11	10
Thioredoxin-like	GST C-terminal domain-like	11	3
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	11	3
PH domain-like	Second domain of FERM	11	11
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	11	8
HCP-like	HCP-like	11	11
(Trans)glycosidases	Glycosyl hydrolase domain	11	3
Homodimeric domain of signal transducing histidine kinase	CheY-like	11	8
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	11	8
SH2 domain	SH3-domain	11	9
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	11	10
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	10	10
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	10	8
Ubiquitin-like	Ubiquitin-like	10	10
Fibronectin type III	Fibronectin type III	9	9
Cysteine-rich domain	PH domain-like	9	9
Phospholipase D/nuclease	Phospholipase D/nuclease	9	6
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	9	2
SH3-domain	DBL homology domain (DH-domain)	9	9
ABC transporter transmembrane region	ABC transporter transmembrane region	9	6
Actin depolymerizing proteins	Actin depolymerizing proteins	9	9
GroEL equatorial domain-like	GroEL apical domain-like	9	2
EF-hand	PLC-like phosphodiesterases	9	8
Protein kinase-like (PK-like)	Cysteine-rich domain	9	9
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	9	9
SH2 domain	Protein kinase-like (PK-like)	9	7
GroEL-intermediate domain like	GroEL apical domain-like	9	2
Ubiquitin-like	Second domain of FERM	9	9
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	9	7
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	9	5
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	9	9
E set domains	E set domains	9	8
Translation proteins	EF-G C-terminal domain-like	8	6
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	8	7
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	8	7
Ankyrin repeat	PH domain-like	8	8
FYVE/PHD zinc finger	FYVE/PHD zinc finger	8	7
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	4
CalX-like	Protein kinase-like (PK-like)	8	5
Protein kinase-like (PK-like)	KA1-like	8	3
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	8	7
Cysteine-rich domain	Cysteine-rich domain	8	8
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	8	6
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	8	6
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	8	6
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	8	8
GroEL equatorial domain-like	GroEL-intermediate domain like	8	1
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	8	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	8	8
GTPase activation domain, GAP	SH3-domain	8	8
Homeodomain-like	Homeodomain-like	8	7
PH domain-like	EF-hand	8	7
Thiolase-like	Thiolase-like	8	4
Nucleic acid-binding proteins	Nucleic acid-binding proteins	7	7
SH3-domain	PX domain	7	7
RING/U-box	Cysteine proteinases	7	6
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	7	6
TSP-1 type 1 repeat	TSP-1 type 1 repeat	7	4
PH domain-like	WD40 repeat-like	7	7
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	7	7
Protein kinase-like (PK-like)	SH3-domain	7	5
CoA-dependent acyltransferases	CoA-dependent acyltransferases	7	1
Complement control module/SCR domain	Growth factor receptor domain	7	7
PreATP-grasp domain	Rudiment single hybrid motif	7	7
ArfGap/RecO-like zinc finger	Ankyrin repeat	7	7
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	7	5
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	7	4
EF-G C-terminal domain-like	EF-G C-terminal domain-like	7	5
EF-hand	EF-hand	7	7
Fibronectin type III	Growth factor receptor domain	7	5
Thioredoxin-like	Thioredoxin-like	7	7
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	7	6
BAR/IMD domain-like	PH domain-like	7	7
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	7	4
Protein kinase-like (PK-like)	beta-sandwich domain of Sec23/24	7	7
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	7	3
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	7	3
Fibronectin type III	Protein kinase-like (PK-like)	7	7
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	7	2
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	7	7
EGF/Laminin	Protein kinase-like (PK-like)	7	4
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	7	7
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	7	4
BRCT domain	BRCT domain	6	6
Protease propeptides/inhibitors	Subtilisin-like	6	3
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	6	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	6	2
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	6	4
PH domain-like	Oxysterol-binding protein-like	6	5
RCC1/BLIP-II	RCC1/BLIP-II	6	5
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	6	4
Calponin-homology domain, CH-domain	EF-hand	6	5
PH domain-like	ArfGap/RecO-like zinc finger	6	6
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	6	5
ARM repeat	PH domain-like	6	6
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	6	3
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	6	5
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	6	5
SH2 domain	EF-hand	6	6
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	6	6
cAMP-binding domain-like	cAMP-binding domain-like	6	6
BAR/IMD domain-like	GTPase activation domain, GAP	6	6
RING/U-box	RING/U-box	6	6
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	6	4
WW domain	PH domain-like	6	6
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	6	4
P-loop containing nucleoside triphosphate hydrolases	Protein kinase-like (PK-like)	6	4
WD40 repeat-like	RING/U-box	6	6
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	6	5
SAM/Pointed domain	PH domain-like	6	6
P-loop containing nucleoside triphosphate hydrolases	SH3-domain	6	6
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	6	5
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	6	5
BEACH domain	WD40 repeat-like	6	6
Translation proteins	Ribosomal protein S5 domain 2-like	6	5
PH domain-like	FYVE/PHD zinc finger	6	6
Concanavalin A-like lectins/glucanases	ARM repeat	5	5
POZ domain	POZ domain	5	5
Ubiquitin-like	SH3-domain	5	5
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	5	4
vWA-like	beta-sandwich domain of Sec23/24	5	4
Clc chloride channel	CBS-domain pair	5	4
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	5	5
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	5	4
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	5	4
SH2 domain	PLC-like phosphodiesterases	5	5
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	5	5
ARM repeat	BEACH domain	5	5
PH domain-like	Calponin-homology domain, CH-domain	5	5
Pectin lyase-like	Protein kinase-like (PK-like)	5	3
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	5	4
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	5	2
SH2 domain	PH domain-like	5	5
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	5	3
Flavoproteins	Riboflavin synthase domain-like	5	4
PH domain-like	PLC-like phosphodiesterases	5	4
Ankyrin repeat	SH3-domain	5	5
Cullin homology domain	"Winged helix" DNA-binding domain	5	3
Zn-finger domain of Sec23/24	vWA-like	5	4
ARM repeat	Formin homology 2 domain (FH2 domain)	5	2
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	5	4
SH2 domain	C2 domain (Calcium/lipid-binding domain, CaLB)	5	5
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	5	5
PH domain-like	(Phosphotyrosine protein) phosphatases II	5	5
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	5	4
Galactose-binding domain-like	Galactose-binding domain-like	5	3
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	5	2
PH domain-like	Ras GEF	5	4
CCCH zinc finger	CCCH zinc finger	5	5
EGF/Laminin	EGF/Laminin	5	4
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	5	5
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	5	2
Ribonuclease H-like	DNA/RNA polymerases	5	3
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	5	2
CBS-domain pair	CBS-domain pair	5	3
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	5	4
PH domain-like	BEACH domain	5	5
Cysteine proteinases	DUSP-like	4	4
SH2 domain	Cysteine-rich domain	4	4
Chromo domain-like	Chromo domain-like	4	2
Complement control module/SCR domain	EGF/Laminin	4	4
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	4	3
PDZ domain-like	PH domain-like	4	4
HIT/MYND zinc finger-like	SET domain	4	3
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	3
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	4	4
TPR-like	HCP-like	4	3
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	4	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	4	4
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	4	3
TPR-like	HIT/MYND zinc finger-like	4	3
Cullin repeat-like	Cullin homology domain	4	2
ARM repeat	Clathrin adaptor appendage domain	4	3
WGR domain-like	Domain of poly(ADP-ribose) polymerase	4	4
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	4	3
Rudiment single hybrid motif	Single hybrid motif	4	4
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	4	3
PreATP-grasp domain	Single hybrid motif	4	4
SH2 domain	SH2 domain	4	4
WGR domain-like	ADP-ribosylation	4	4
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	4	3
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	4	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	4
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	4	3
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	4	4
UBA-like	Ubiquitin-like	4	4
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	4	1
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	4	2
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	4
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	4	4
L domain-like	RNI-like	4	4
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	4	3
Concanavalin A-like lectins/glucanases	WD40 repeat-like	4	4
vWA-like	Helical domain of Sec23/24	4	3
PYP-like sensor domain (PAS domain)	CheY-like	4	3
SAM/Pointed domain	SH3-domain	4	4
Cullin repeat-like	"Winged helix" DNA-binding domain	4	2
WD40 repeat-like	beta-sandwich domain of Sec23/24	4	4
Complement control module/SCR domain	CalX-like	4	4
t-snare proteins	SNARE fusion complex	4	3
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	4	4
ClpP/crotonase	ClpP/crotonase	4	3
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	4	4
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	4	4
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	4	3
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	4	3
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	4	3
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	4	4
Aconitase iron-sulfur domain	LeuD/IlvD-like	4	3
Concanavalin A-like lectins/glucanases	BEACH domain	4	4
PX domain	BAR/IMD domain-like	4	3
WW domain	Hect, E3 ligase catalytic domain	4	4
Ankyrin repeat	Protein kinase-like (PK-like)	4	3
Regulator of G-protein signaling, RGS	PX domain	4	3
Concanavalin A-like lectins/glucanases	PH domain-like	4	4
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	4	4
P-loop containing nucleoside triphosphate hydrolases	TPR-like	4	4
TPR-like	Chaperone J-domain	3	3
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	3	3
cAMP-binding domain-like	Ras GEF	3	3
Periplasmic binding protein-like II	Protein kinase-like (PK-like)	3	3
E set domains	P-loop containing nucleoside triphosphate hydrolases	3	3
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	3	2
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	2
PurM N-terminal domain-like	PurM C-terminal domain-like	3	3
Protein kinase-like (PK-like)	Nucleotide cyclase	3	3
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	3	3
PA domain	RING/U-box	3	2
DNA repair protein MutS, domain III	DNA repair protein MutS, domain III	3	3
Ankyrin repeat	Hect, E3 ligase catalytic domain	3	3
Protein kinase-like (PK-like)	HCP-like	3	3
BRCT domain	Nucleotidyltransferase	3	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	3
ENTH/VHS domain	GAT-like domain	3	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	3	3
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	3	3
BRCT domain	ADP-ribosylation	3	3
Ribosomal L27 protein-like	Nucleic acid-binding proteins	3	2
Spectrin repeat	Spectrin repeat	3	3
Ankyrin repeat	SAM/Pointed domain	3	3
Translation proteins	ThrRS/AlaRS common domain	3	3
GroES-like	GroES-like	3	2
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	3	1
Translational machinery components	L30e-like	3	3
Ubiquitin-like	ARM repeat	3	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	3	3
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	3	2
L domain-like	PP2C-like	3	3
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	3	2
Galactose mutarotase-like	(Trans)glycosidases	3	1
Ubiquitin-like	Protein kinase-like (PK-like)	3	2
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	3	3
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	3	2
Calponin-homology domain, CH-domain	Spectrin repeat	3	3
Cysteine-rich domain	EF-hand	3	3
Ubiquitin-like	Thioredoxin-like	3	3
FAD/NAD(P)-binding domain	EF-hand	3	3
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	3	2
Single hybrid motif	CoA-dependent acyltransferases	3	3
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	3	3
Ubiquitin-like	Cap-Gly domain	3	2
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	3	1
Carbamate kinase-like	ACT-like	3	3
PDZ domain-like	P-loop containing nucleoside triphosphate hydrolases	3	3
BRCT domain	DNA polymerase beta, N-terminal domain-like	3	3
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	3	3
HMG-box	HMG-box	3	3
Zn2/Cys6 DNA-binding domain	PYP-like sensor domain (PAS domain)	3	3
PH domain-like	PX domain	3	3
HCP-like	HIT/MYND zinc finger-like	3	2
(Phosphotyrosine protein) phosphatases II	FYVE/PHD zinc finger	3	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	3	3
Spermadhesin, CUB domain	EGF/Laminin	3	3
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	3	3
Cysteine-rich domain	DBL homology domain (DH-domain)	3	3
Ubiquitin-like	Ras GEF	3	3
ACT-like	ACT-like	3	3
MIR domain	IP3 receptor type 1 binding core, domain 2	3	3
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	3	3
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	3
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	3	3
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
PKD domain	PKD domain	3	2
BRCT domain	WGR domain-like	3	3
BAR/IMD domain-like	Ankyrin repeat	3	3
Growth factor receptor domain	Concanavalin A-like lectins/glucanases	3	3
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	1
UBA-like	UBA-like	3	3
Protein kinase-like (PK-like)	PX domain	3	3
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	2
Concanavalin A-like lectins/glucanases	SH3-domain	3	3
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	3	3
ARM repeat	RING/U-box	3	3
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	3
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	3	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Glucocorticoid receptor-like (DNA-binding domain)	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	3	3
GTPase activation domain, GAP	Glucocorticoid receptor-like (DNA-binding domain)	3	3
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	3	3
E set domains	Concanavalin A-like lectins/glucanases	3	3
SET domain	SET domain	3	3
SNARE-like	SNARE fusion complex	3	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	PX domain	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	3	3
TPR-like	ARM repeat	3	3
TSP-1 type 1 repeat	Concanavalin A-like lectins/glucanases	3	3
Tudor/PWWP/MBT	FYVE/PHD zinc finger	3	3
F-box domain	RNI-like	3	3
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	3	3
Ankyrin repeat	FYVE/PHD zinc finger	3	3
Galactose mutarotase-like	Glycosyl hydrolase domain	3	1
PLP-binding barrel	Alanine racemase C-terminal domain-like	3	3
PsbU/PolX domain-like	Nucleotidyltransferase	3	3
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	3	3
BRCT domain	PsbU/PolX domain-like	3	3
Ubiquitin-like	Ankyrin repeat	3	3
EF-hand	RING/U-box	3	3
SAM/Pointed domain	GTPase activation domain, GAP	3	3
Protein kinase-like (PK-like)	GTPase activation domain, GAP	3	3
TSP-1 type 1 repeat	SH3-domain	3	3
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	3	2
P-loop containing nucleoside triphosphate hydrolases	GTPase activation domain, GAP	3	3
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	3	3
PH domain-like	"Winged helix" DNA-binding domain	3	3
Galactose-binding domain-like	(Trans)glycosidases	3	2
Ubiquitin-like	Cysteine proteinases	3	3
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	3	3
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	3	3
ISP domain	Bet v1-like	3	1
FYVE/PHD zinc finger	Clavaminate synthase-like	3	3
Protein kinase-like (PK-like)	Glucocorticoid receptor-like (DNA-binding domain)	3	3
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	3	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	3	2
Sec7 domain	PH domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	3	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	3	2
Protein kinase-like (PK-like)	WD40 repeat-like	3	3
Cysteine-rich domain	GTPase activation domain, GAP	3	3
SAM/Pointed domain	SAM/Pointed domain	3	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	2
TPR-like	WD40 repeat-like	3	3
Metalloproteases ("zincins"), catalytic domain	SH3-domain	3	3
SAM/Pointed domain	Ubiquitin-like	3	3
PriA/YqbF domain	GINS helical bundle-like	3	2
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	3	3
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	3	2
Tropomyosin	P-loop containing nucleoside triphosphate hydrolases	3	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	3	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	3	2
"Winged helix" DNA-binding domain	beta-sandwich domain of Sec23/24	3	3
Ubiquitin-like	L domain-like	3	3
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	3	3
Ribonuclease H-like	Ribonuclease H-like	3	3
BRCT domain	Domain of poly(ADP-ribose) polymerase	3	3
ARM repeat	Subdomain of clathrin and coatomer appendage domain	3	2
PDZ domain-like	PDZ domain-like	3	3
CRAL/TRIO domain	PH domain-like	3	3
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	3	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	2	1
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	2	2
Class I glutamine amidotransferase-like	PreATP-grasp domain	2	2
Calponin-homology domain, CH-domain	SH2 domain	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	GAF domain-like	2	2
beta-lactamase/transpeptidase-like	Ankyrin repeat	2	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	2	2
L domain-like	SAM/Pointed domain	2	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	2	2
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	2	2
EF-hand	Mitochondrial carrier	2	2
CheY-like	GAF domain-like	2	2
ENTH/VHS domain	SH3-domain	2	2
UBA-like	UBC-like	2	2
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	2	2
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	2	2
RNI-like	Growth factor receptor domain	2	2
PH domain-like	CRAL/TRIO N-terminal domain	2	2
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	2
p53-like transcription factors	Ankyrin repeat	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	2	2
CCCH zinc finger	RING/U-box	2	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	2	2
L domain-like	Fibronectin type III	2	2
Protease propeptides/inhibitors	Zn-dependent exopeptidases	2	1
FYVE/PHD zinc finger	SET domain	2	2
HAD-like	Protein kinase-like (PK-like)	2	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	2	2
POZ domain	Ankyrin repeat	2	2
Macro domain-like	ADP-ribosylation	2	2
"Winged helix" DNA-binding domain	E set domains	2	2
SH2 domain	GTPase activation domain, GAP	2	2
SMAD/FHA domain	BRCT domain	2	2
Cysteine-rich domain	SAM/Pointed domain	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	2	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	2	1
Protein kinase-like (PK-like)	Bet v1-like	2	1
PH domain-like	Glucocorticoid receptor-like (DNA-binding domain)	2	2
Ubiquitin-like	PP2C-like	2	2
I/LWEQ domain	Ubiquitin-like	2	2
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	1
Nucleotide-diphospho-sugar transferases	HAD-like	2	1
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	2	2
ARM repeat	Rap/Ran-GAP	2	2
Ankyrin repeat	Domain of poly(ADP-ribose) polymerase	2	2
DBL homology domain (DH-domain)	Ubiquitin-like	2	2
SCP-like	SCP-like	2	2
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	2	2
PDZ domain-like	SH3-domain	2	2
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	2	2
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	2	1
PX domain	RING/U-box	2	2
PA domain	Zn-dependent exopeptidases	2	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	2	2
PH domain-like	Ypt/Rab-GAP domain of gyp1p	2	1
HLH, helix-loop-helix DNA-binding domain	TPR-like	2	2
Second domain of FERM	Second domain of FERM	2	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
AN1-like Zinc finger	AN1-like Zinc finger	2	2
Saposin	Saposin	2	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	2	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	2	2
ADC-like	Cdc48 domain 2-like	2	1
Translation proteins SH3-like domain	Nucleic acid-binding proteins	2	2
EF-hand	Protein kinase-like (PK-like)	2	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	2	2
vWA-like	SPOC domain-like	2	2
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	2	2
Chromo domain-like	Tudor/PWWP/MBT	2	2
I/LWEQ domain	alpha-catenin/vinculin-like	2	2
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	2	2
RUN domain-like	FYVE/PHD zinc finger	2	1
FF domain	FF domain	2	2
Growth factor receptor domain	TSP-1 type 1 repeat	2	2
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	2	2
Homodimeric domain of signal transducing histidine kinase	GAF domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	BRCT domain	2	2
Metalloproteases ("zincins"), catalytic domain	Concanavalin A-like lectins/glucanases	2	2
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	2	2
RCC1/BLIP-II	PH domain-like	2	2
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	2
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	2	2
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	2	2
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	2	2
Glucocorticoid receptor-like (DNA-binding domain)	Rap/Ran-GAP	2	2
Acetyl-CoA synthetase-like	NAD(P)-binding Rossmann-fold domains	2	2
Periplasmic binding protein-like I	Growth factor receptor domain	2	2
POZ domain	Skp1 dimerisation domain-like	2	1
Ubiquitin-like	Nucleotide cyclase	2	2
ACT-like	NAD(P)-binding Rossmann-fold domains	2	2
FYVE/PHD zinc finger	Bromodomain	2	2
DBL homology domain (DH-domain)	GTPase activation domain, GAP	2	2
Sec63 N-terminal domain-like	E set domains	2	2
UBC-like	RING/U-box	2	2
vWA-like	EGF/Laminin	2	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	2	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	2	2
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	2	2
Globin-like	Globin-like	2	1
E set domains	FYVE/PHD zinc finger	2	2
ARM repeat	Second domain of FERM	2	2
FYSH domain	Hypothetical protein AF0491, middle domain	2	2
Homeodomain-like	Glucocorticoid receptor-like (DNA-binding domain)	2	2
Soluble quinoprotein glucose dehydrogenase	PKD domain	2	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	2	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	2	2
PH domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	2	2
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	2	2
Amine oxidase N-terminal region	Amine oxidase catalytic domain	2	2
IP3 receptor type 1 binding core, domain 2	IP3 receptor type 1 binding core, domain 2	2	2
Ankyrin repeat	Clavaminate synthase-like	2	2
BRCT domain	Ankyrin repeat	2	2
FKBP-like	TPR-like	2	2
PK beta-barrel domain-like	PK C-terminal domain-like	2	2
Nucleotide cyclase	Glucocorticoid receptor-like (DNA-binding domain)	2	2
UDP-Glycosyltransferase/glycogen phosphorylase	TPR-like	2	2
L domain-like	Family A G protein-coupled receptor-like	2	2
Ubiquitin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	SH3-domain	2	2
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	2	2
GTPase activation domain, GAP	GTPase activation domain, GAP	2	2
PreATP-grasp domain	ClpP/crotonase	2	2
CAD & PB1 domains	Protein kinase-like (PK-like)	2	2
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	2	2
GTPase activation domain, GAP	RGC domain-like	2	2
PX domain	EF-hand	2	2
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	2	2
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	2	2
BRCT domain	DNA ligase/mRNA capping enzyme, catalytic domain	2	2
TPR-like	"Winged helix" DNA-binding domain	2	2
FMN-linked oxidoreductases	alpha-helical ferredoxin	2	2
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	2	2
beta-sandwich domain of Sec23/24	ARM repeat	2	2
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Notch domain	Ankyrin repeat	2	1
L domain-like	Nucleotide cyclase	2	2
Histone-fold	Ras GEF	2	2
PDZ domain-like	WW domain	2	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
Cysteine-rich domain	SH3-domain	2	2
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	1
PH domain-like	RUN domain-like	2	2
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	2	1
Rudiment single hybrid motif	ClpP/crotonase	2	2
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	2	2
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	2	2
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	2	2
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	2	1
WD40 repeat-like	FYVE/PHD zinc finger	2	2
PLP-dependent transferases	PLP-dependent transferases	2	2
RING/U-box	BRCT domain	2	2
Galactose-binding domain-like	PKD domain	2	2
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	2	2
Ankyrin repeat	ADP-ribosylation	2	2
NAD kinase/diacylglycerol kinase-like	NAD kinase/diacylglycerol kinase-like	2	1
PA domain	Transferrin receptor-like dimerisation domain	2	1
PP2C-like	Nucleotide cyclase	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	1
PDZ domain-like	DBL homology domain (DH-domain)	2	2
Protein kinase-like (PK-like)	SAM/Pointed domain	2	2
Ribonuclease H-like	HRDC-like	2	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	2	2
Nucleotide-diphospho-sugar transferases	Protein kinase-like (PK-like)	2	1
PreATP-grasp domain	Methylglyoxal synthase-like	2	2
FYVE/PHD zinc finger	Concanavalin A-like lectins/glucanases	2	2
Amine oxidase N-terminal region	Amine oxidase N-terminal region	2	2
Mob1/phocein	GTPase activation domain, GAP	2	1
Nucleotide-binding domain	Nucleotide-binding domain	2	2
Ubiquitin-like	ArfGap/RecO-like zinc finger	2	2
Periplasmic binding protein-like II	Nucleotide cyclase	2	2
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	2	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	2	1
L domain-like	TSP-1 type 1 repeat	2	2
PreATP-grasp domain	PreATP-grasp domain	2	2
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	2	2
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	2
Ankyrin repeat	PLC-like phosphodiesterases	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Nucleotide cyclase	2	2
Mitochondrial carrier	Mitochondrial carrier	2	1
Kelch motif	Galactose oxidase, central domain	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	2	2
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
Pentapeptide repeat-like	WD40 repeat-like	2	2
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	2
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	2	1
(Phosphotyrosine protein) phosphatases II	Cysteine-rich domain	2	2
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	2	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
L domain-like	SH3-domain	2	2
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	2	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	2	2
Spermadhesin, CUB domain	Kelch motif	2	2
Periplasmic binding protein-like II	ACT-like	2	1
WD40 repeat-like	DPP6 N-terminal domain-like	2	2
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	2	2
Spectrin repeat	EF-hand	2	2
Homeodomain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
HMA, heavy metal-associated domain	HAD-like	2	2
Calponin-homology domain, CH-domain	Cysteine-rich domain	2	2
Adenine nucleotide alpha hydrolases-like	Adenine nucleotide alpha hydrolases-like	2	2
Cadherin-like	Cadherin-like	2	2
FYVE/PHD zinc finger	ARM repeat	2	2
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	2	1
cAMP-binding domain-like	FabD/lysophospholipase-like	2	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	2	2
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	2	2
Clathrin heavy-chain terminal domain	ARM repeat	2	2
Myosin rod fragments	Myosin rod fragments	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
CheY-like	CheY-like	2	2
Bromodomain	Bromodomain	2	2
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	2	2
GTPase activation domain, GAP	Nucleotide cyclase	2	2
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	2	2
p53-like transcription factors	E set domains	2	2
Nucleotidylyl transferase	Nucleotidylyl transferase	2	1
P-loop containing nucleoside triphosphate hydrolases	SH2 domain	2	1
SH3-domain	HIT/MYND zinc finger-like	2	2
MgtE membrane domain-like	MgtE membrane domain-like	2	1
Anthrax protective antigen	Nucleotide-diphospho-sugar transferases	2	2
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	2	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	2	1
BRCT domain	Nucleic acid-binding proteins	2	2
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	2	2
PH domain-like	VHP, Villin headpiece domain	2	2
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
Protein kinase-like (PK-like)	TPR-like	2	2
ARM repeat	Sec7 domain	2	2
Protein kinase-like (PK-like)	Myosin rod fragments	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	2
alpha-helical ferredoxin	Nucleotide-binding domain	2	2
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	2	2
ACP-like	NAD(P)-binding Rossmann-fold domains	2	2
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
SH2 domain	RING/U-box	2	2
Kelch motif	Kelch motif	2	2
Acetyl-CoA synthetase-like	ACP-like	2	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	2	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	2	2
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
ADP-ribosylation	P-loop containing nucleoside triphosphate hydrolases	2	2
ARID-like	ARM repeat	2	2
RCC1/BLIP-II	POZ domain	2	2
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	2	2
NAD(P)-binding Rossmann-fold domains	SCP-like	2	2
SNARE fusion complex	SNARE fusion complex	2	2
SH3-domain	WW domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	2	1
Surp module (SWAP domain)	Surp module (SWAP domain)	2	2
(Trans)glycosidases	(Trans)glycosidases	2	2
HLH, helix-loop-helix DNA-binding domain	Hemopexin-like domain	2	2
beta-sandwich domain of Sec23/24	SH3-domain	2	2
NAD(P)-binding Rossmann-fold domains	Thioesterase/thiol ester dehydrase-isomerase	2	2
RNA-binding domain, RBD	Cyclophilin-like	2	2
EGF/Laminin	Kelch motif	2	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	2	2
TPR-like	RING/U-box	2	2
Oligoxyloglucan reducing end-specific cellobiohydrolase	PKD domain	2	1
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	2	2
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	2
Chromo domain-like	FYVE/PHD zinc finger	2	2
SAP domain	ADP-ribosylation	2	2
E set domains	Ankyrin repeat	2	2
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	2	2
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	2	2
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	2	2
Initiation factor IF2/eIF5b, domain 3	Translation proteins	2	1
DBL homology domain (DH-domain)	PX domain	2	2
Ankyrin repeat	L domain-like	2	2
FMN-linked oxidoreductases	Nucleotide-binding domain	2	2
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	2	1
Ubiquitin-like	GTPase activation domain, GAP	2	2
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	2	2
Bet v1-like	Bet v1-like	2	2
Nucleotide cyclase	Nucleotide cyclase	2	2
Tryptophan synthase beta subunit-like PLP-dependent enzymes	CBS-domain pair	2	1
Restriction endonuclease-like	RuvA domain 2-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	2	2
Ankyrin repeat	WGR domain-like	2	2
cAMP-binding domain-like	Ubiquitin-like	2	2
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	2	2
PDZ domain-like	Ras GEF	2	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	2	2
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	1
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	1	1
beta-sandwich domain of Sec23/24	FYVE/PHD zinc finger	1	1
Lipovitellin-phosvitin complex, superhelical domain	Fibronectin type III	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
RING/U-box	NAD(P)-binding Rossmann-fold domains	1	1
HIT/MYND zinc finger-like	Second domain of FERM	1	1
NHL repeat	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	1	1
Myosin rod fragments	PH domain-like	1	1
Ankyrin repeat	Acyl-CoA binding protein	1	1
Metallo-dependent phosphatases	SCP-like	1	1
Ras GEF	GTPase activation domain, GAP	1	1
Chorismate mutase II	Chorismate mutase II	1	1
Regulator of G-protein signaling, RGS	DBL homology domain (DH-domain)	1	1
Macro domain-like	CRAL/TRIO domain	1	1
ARM repeat	Ras GEF	1	1
Kringle-like	PKD domain	1	1
Concanavalin A-like lectins/glucanases	Kelch motif	1	1
RNA-binding domain, RBD	dsRNA-binding domain-like	1	1
WW domain	Cysteine proteinases	1	1
Cysteine-rich domain	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HIT/MYND zinc finger-like	1	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Cap-Gly domain	Cap-Gly domain	1	1
SH3-domain	DPP6 N-terminal domain-like	1	1
Galactose-binding domain-like	Spermadhesin, CUB domain	1	1
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	1	1
GroEL-intermediate domain like	SAICAR synthase-like	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Second domain of FERM	alpha-catenin/vinculin-like	1	1
GST C-terminal domain-like	Class II aaRS and biotin synthetases	1	1
SAM/Pointed domain	Calponin-homology domain, CH-domain	1	1
Tricorn protease domain 2	WD40 repeat-like	1	1
PX domain	Cell wall binding repeat	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
Prokaryotic ribosomal protein L17	Prokaryotic ribosomal protein L17	1	1
Growth factor receptor domain	Galactose-binding domain-like	1	1
PX domain	Actin-like ATPase domain	1	1
GroEL equatorial domain-like	GTPase activation domain, GAP	1	1
P-loop containing nucleoside triphosphate hydrolases	PX domain	1	1
Protein kinase-like (PK-like)	Rhodanese/Cell cycle control phosphatase	1	1
Galactose-binding domain-like	SAM/Pointed domain	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
L domain-like	UBA-like	1	1
dsRNA-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Oxysterol-binding protein-like	Oxysterol-binding protein-like	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
C-type lectin-like	PKD domain	1	1
FabD/lysophospholipase-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
Ankyrin repeat	Oxysterol-binding protein-like	1	1
Homocysteine S-methyltransferase	Dihydropteroate synthetase-like	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
Zn-dependent exopeptidases	Zn-dependent exopeptidases	1	1
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	1	1
Second domain of FERM	RNI-like	1	1
A middle domain of Talin 1	I/LWEQ domain	1	1
Phosphoenolpyruvate/pyruvate domain	NAD(P)-binding Rossmann-fold domains	1	1
PYP-like sensor domain (PAS domain)	beta-sandwich domain of Sec23/24	1	1
RING/U-box	DUSP-like	1	1
Ubiquitin-like	A middle domain of Talin 1	1	1
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	1	1
Concanavalin A-like lectins/glucanases	Hect, E3 ligase catalytic domain	1	1
Cysteine proteinases	Cysteine proteinases	1	1
Ribosomal protein L6	Ribosomal protein L6	1	1
PreATP-grasp domain	Aldolase	1	1
Dehydroquinate synthase-like	Aldolase	1	1
SMAD/FHA domain	PX domain	1	1
P-loop containing nucleoside triphosphate hydrolases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Metallo-dependent phosphatases	P-loop containing nucleoside triphosphate hydrolases	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
RING/U-box	TRAF domain-like	1	1
Ubiquitin-like	RNI-like	1	1
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	1	1
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	1	1
Tudor/PWWP/MBT	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
beta-sandwich domain of Sec23/24	GTPase activation domain, GAP	1	1
Hemopexin-like domain	Integrin alpha N-terminal domain	1	1
Ypt/Rab-GAP domain of gyp1p	EF-hand	1	1
Carbohydrate-binding domain	Chitinase insertion domain	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Concanavalin A-like lectins/glucanases	FabD/lysophospholipase-like	1	1
Carbohydrate-binding domain	(Trans)glycosidases	1	1
Protein kinase-like (PK-like)	Hect, E3 ligase catalytic domain	1	1
EF-hand	SAICAR synthase-like	1	1
Quinoprotein alcohol dehydrogenase-like	TolB, C-terminal domain	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
SMAD/FHA domain	"Winged helix" DNA-binding domain	1	1
Bromodomain	Hect, E3 ligase catalytic domain	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
ISP domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
WD40 repeat-like	UBA-like	1	1
Kringle-like	Anthrax protective antigen	1	1
SCP-like	FYVE/PHD zinc finger	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Calponin-homology domain, CH-domain	RGC domain-like	1	1
GatB/YqeY motif	GatB/YqeY motif	1	1
Ribulose-phoshate binding barrel	Tryptophan synthase beta subunit-like PLP-dependent enzymes	1	1
RCC1/BLIP-II	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
HD-domain/PDEase-like	Nucleotide cyclase	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
CRAL/TRIO domain	PapD-like	1	1
GTPase activation domain, GAP	EF-hand	1	1
Saposin	Metallo-dependent phosphatases	1	1
Galactose-binding domain-like	Ricin B-like lectins	1	1
PUA domain-like	Nucleotidylyl transferase	1	1
GST C-terminal domain-like	S15/NS1 RNA-binding domain	1	1
Transcription factor STAT-4 N-domain	STAT	1	1
ISP transmembrane anchor	ISP domain	1	1
Aconitase iron-sulfur domain	Aconitase iron-sulfur domain	1	1
SAM/Pointed domain	Tudor/PWWP/MBT	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Cysteine proteinases	1	1
PPK N-terminal domain-like	Phospholipase D/nuclease	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
SCP-like	beta-lactamase/transpeptidase-like	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	1	1
Cysteine-rich domain	ArfGap/RecO-like zinc finger	1	1
EF-hand	DBL homology domain (DH-domain)	1	1
PX domain	Cyclin-like	1	1
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	1	1
CheY-like	HLH, helix-loop-helix DNA-binding domain	1	1
RING/U-box	PUA domain-like	1	1
EF-hand	FYVE/PHD zinc finger	1	1
A middle domain of Talin 1	alpha-catenin/vinculin-like	1	1
Six-hairpin glycosidases	Galactose-binding domain-like	1	1
Clavaminate synthase-like	beta-sandwich domain of Sec23/24	1	1
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	1	1
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	1	1
(Phosphotyrosine protein) phosphatases II	Clathrin heavy-chain terminal domain	1	1
GST C-terminal domain-like	Class II aaRS ABD-related	1	1
RmlC-like cupins	RNI-like	1	1
Homocysteine S-methyltransferase	Methionine synthase domain	1	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	VPS9 domain	1	1
p53-like transcription factors	SAM/Pointed domain	1	1
RING/U-box	Acetyl-CoA synthetase-like	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
Chromo domain-like	Arginase/deacetylase	1	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Ribulose-phoshate binding barrel	Ribulose-phoshate binding barrel	1	1
Annexin	Annexin	1	1
RING/U-box	Ankyrin repeat	1	1
BRCT domain	Protein kinase-like (PK-like)	1	1
NAD(P)-binding Rossmann-fold domains	4'-phosphopantetheinyl transferase	1	1
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
Nucleic acid-binding proteins	TPR-like	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	ARM repeat	1	1
Aldolase	post-HMGL domain-like	1	1
SCP-like	Protein kinase-like (PK-like)	1	1
(Trans)glycosidases	Chitinase insertion domain	1	1
RCC1/BLIP-II	Concanavalin A-like lectins/glucanases	1	1
Rhomboid-like	UBA-like	1	1
DBL homology domain (DH-domain)	BAR/IMD domain-like	1	1
PH domain-like	PP2C-like	1	1
Spermadhesin, CUB domain	C-type lectin-like	1	1
ADP-ribosylation	14-3-3 protein	1	1
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
L domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Cysteine proteinases	beta-sandwich domain of Sec23/24	1	1
Rhodanese/Cell cycle control phosphatase	Cysteine proteinases	1	1
PDZ domain-like	BAR/IMD domain-like	1	1
PHM/PNGase F	NHL repeat	1	1
GroEL apical domain-like	GTPase activation domain, GAP	1	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	1	1
PP2C-like	Protein kinase-like (PK-like)	1	1
HSP20-like chaperones	Thioredoxin-like	1	1
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
Pseudo ankyrin repeat-like	Homeodomain-like	1	1
STAT	SH2 domain	1	1
Ubiquitin-like	HIT/MYND zinc finger-like	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
PH domain-like	beta-sandwich domain of Sec23/24	1	1
alpha/beta-Hydrolases	(Phosphotyrosine protein) phosphatases II	1	1
MoaD/ThiS	Molybdopterin synthase subunit MoaE	1	1
Chaperone J-domain	Homeodomain-like	1	1
HAD-like	alpha/beta-Hydrolases	1	1
Spermadhesin, CUB domain	Kringle-like	1	1
RNI-like	HAD-like	1	1
PH domain-like	CAD & PB1 domains	1	1
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	1	1
Integrin alpha N-terminal domain	Anthrax protective antigen	1	1
Rap/Ran-GAP	Ras GEF	1	1
Bromodomain	RING/U-box	1	1
TRAF domain-like	WD40 repeat-like	1	1
PH domain-like	Rap/Ran-GAP	1	1
Ankyrin repeat	Nudix	1	1
WW domain	GTPase activation domain, GAP	1	1
GTPase activation domain, GAP	Cell wall binding repeat	1	1
Surp module (SWAP domain)	Formin homology 2 domain (FH2 domain)	1	1
CAD & PB1 domains	SAM/Pointed domain	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
LDL receptor-like module	Mannose 6-phosphate receptor domain	1	1
Class II aaRS and biotin synthetases	Translation proteins	1	1
Galactose-binding domain-like	C-type lectin-like	1	1
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	1	1
Pectin lyase-like	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
PYP-like sensor domain (PAS domain)	GAF domain-like	1	1
Ribosomal protein L25-like	C-terminal domain of ProRS	1	1
Class II aaRS ABD-related	C-terminal domain of ProRS	1	1
Kringle-like	Integrin alpha N-terminal domain	1	1
Dipeptidyl peptidase I (cathepsin C), exclusion domain	Cysteine proteinases	1	1
PH domain-like	Actin depolymerizing proteins	1	1
"Winged helix" DNA-binding domain	GroEL-intermediate domain like	1	1
RING/U-box	FYVE/PHD zinc finger	1	1
EF-hand	SH3-domain	1	1
Aldolase	Single hybrid motif	1	1
SH3-domain	I/LWEQ domain	1	1
EPT/RTPC-like	RNA 3'-terminal phosphate cyclase, RPTC, insert domain	1	1
TAZ domain	Bromodomain	1	1
CRAL/TRIO N-terminal domain	PapD-like	1	1
Kelch motif	Ankyrin repeat	1	1
WW domain	Second domain of FERM	1	1
F-box domain	ApaG-like	1	1
Ubiquitin-like	Rap/Ran-GAP	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Regulator of G-protein signaling, RGS	1	1
vWA-like	C-terminal domain of Ku80	1	1
Six-hairpin glycosidases	Protein kinase-like (PK-like)	1	1
PH domain-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	WW domain	1	1
DNA clamp	DNA clamp	1	1
HLH, helix-loop-helix DNA-binding domain	CRAL/TRIO N-terminal domain	1	1
DNase I-like	UBA-like	1	1
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	1	1
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	1	1
NAD kinase/diacylglycerol kinase-like	GTPase activation domain, GAP	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
DNA/RNA polymerases	DNA/RNA polymerases	1	1
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	1	1
Adenine nucleotide alpha hydrolases-like	PUA domain-like	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	1	1
Ribosomal protein L25-like	S15/NS1 RNA-binding domain	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
Macro domain-like	BRCT domain	1	1
Macro domain-like	DHS-like NAD/FAD-binding domain	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
Cu,Zn superoxide dismutase-like	Cu,Zn superoxide dismutase-like	1	1
p53-like transcription factors	SH2 domain	1	1
IP3 receptor type 1 binding core, domain 2	EF-hand	1	1
Glucocorticoid receptor-like (DNA-binding domain)	PDZ domain-like	1	1
"Winged helix" DNA-binding domain	SAICAR synthase-like	1	1
Cysteine proteinases	UBA-like	1	1
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	1	1
CRAL/TRIO domain	DBL homology domain (DH-domain)	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
TPR-like	CAD & PB1 domains	1	1
GAF domain-like	HD-domain/PDEase-like	1	1
Arp2/3 complex subunits	Arp2/3 complex subunits	1	1
SH2 domain	DNase I-like	1	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	1	1
alpha/beta-Hydrolases	Protein kinase-like (PK-like)	1	1
BRCT domain	DNA/RNA polymerases	1	1
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	1	1
RUN domain-like	Multiheme cytochromes	1	1
SMAD/FHA domain	ADP-ribosylation	1	1
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	1	1
RING/U-box	GST C-terminal domain-like	1	1
TRAF domain-like	TRAF domain-like	1	1
PH domain-like	Actin-like ATPase domain	1	1
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Ankyrin repeat	Glucocorticoid receptor-like (DNA-binding domain)	1	1
E set domains	(Trans)glycosidases	1	1
post-HMGL domain-like	Single hybrid motif	1	1
Integrin alpha N-terminal domain	Integrin alpha N-terminal domain	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	1	1
SH3-domain	CAD & PB1 domains	1	1
HIT-like	HIT-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	E set domains	1	1
P-loop containing nucleoside triphosphate hydrolases	PLP-dependent transferases	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	Hedgehog/intein (Hint) domain	1	1
Homocysteine S-methyltransferase	Cobalamin (vitamin B12)-binding domain	1	1
PapD-like	Protein kinase-like (PK-like)	1	1
Metallo-dependent phosphatases	RNA-binding domain, RBD	1	1
PreATP-grasp domain	Metallo-dependent hydrolases	1	1
Cysteine proteinases	PH domain-like	1	1
Ankyrin repeat	Fibronectin type III	1	1
Apolipoprotein A-I	WD40 repeat-like	1	1
Mannose 6-phosphate receptor domain	Protein kinase-like (PK-like)	1	1
Galactose-binding domain-like	Kringle-like	1	1
Dihydropteroate synthetase-like	Methionine synthase domain	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	1	1
beta-sandwich domain of Sec23/24	Ras GEF	1	1
WW domain	Calponin-homology domain, CH-domain	1	1
Ankyrin repeat	RNI-like	1	1
Bromodomain	SET domain	1	1
Class I glutamine amidotransferase-like	Glycoside hydrolase/deacetylase	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
EF-hand	ARM repeat	1	1
Hedgehog/intein (Hint) domain	Hedgehog/intein (Hint) domain	1	1
SAM/Pointed domain	ArfGap/RecO-like zinc finger	1	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	1	1
SH3-domain	Cell wall binding repeat	1	1
FAD-linked reductases, C-terminal domain	Aminomethyltransferase beta-barrel domain	1	1
Galactose-binding domain-like	BRCT domain	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
SH3-domain	Second domain of FERM	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Voltage-gated potassium channels	TrkA C-terminal domain-like	1	1
HMG-box	FYVE/PHD zinc finger	1	1
Glycerol-3-phosphate (1)-acyltransferase	Glycerol-3-phosphate (1)-acyltransferase	1	1
Lipovitellin-phosvitin complex, superhelical domain	Growth factor receptor domain	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
Methionine synthase domain	Cobalamin (vitamin B12)-binding domain	1	1
RUN domain-like	SH3-domain	1	1
GroEL apical domain-like	SAICAR synthase-like	1	1
EF-hand	DUSP-like	1	1
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	1	1
RCC1/BLIP-II	VPS9 domain	1	1
STAT	p53-like transcription factors	1	1
Kix domain of CBP (creb binding protein)	Bromodomain	1	1
HisI-like	all-alpha NTP pyrophosphatases	1	1
Second domain of FERM	I/LWEQ domain	1	1
PH domain-like	HMG-box	1	1
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	1	1
PreATP-grasp domain	PurM C-terminal domain-like	1	1
CCCH zinc finger	Phospholipase D/nuclease	1	1
PX domain	SAP domain	1	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	1	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
TPR-like	Ankyrin repeat	1	1
GTPase activation domain, GAP	Bet v1-like	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
Leucine zipper domain	SAM/Pointed domain	1	1
Metalloproteases ("zincins"), catalytic domain	UBA-like	1	1
ArfGap/RecO-like zinc finger	GTPase activation domain, GAP	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
beta-sandwich domain of Sec23/24	HAD-like	1	1
Class I glutamine amidotransferase-like	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	1	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	1	1
Macro domain-like	Nudix	1	1
Kringle-like	C-type lectin-like	1	1
Expressed protein At2g23090/F21P24.15	Expressed protein At2g23090/F21P24.15	1	1
Glucocorticoid receptor-like (DNA-binding domain)	PLC-like phosphodiesterases	1	1
Calponin-homology domain, CH-domain	SH3-domain	1	1
F-box domain	Galactose-binding domain-like	1	1
PX domain	CAD & PB1 domains	1	1
SH3-domain	WD40 repeat-like	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
ArfGap/RecO-like zinc finger	PX domain	1	1
NAD(P)-binding Rossmann-fold domains	Thiolase-like	1	1
UBA-like	SAM/Pointed domain	1	1
SH2 domain	(Phosphotyrosine protein) phosphatases II	1	1
SH2 domain	SAM/Pointed domain	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Cobalamin adenosyltransferase-like	Cobalamin adenosyltransferase-like	1	1
PH domain-like	Bet v1-like	1	1
I/LWEQ domain	Ankyrin repeat	1	1
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
Ras GEF	NAD kinase/diacylglycerol kinase-like	1	1
ENTH/VHS domain	L domain-like	1	1
14-3-3 protein	Actin-like ATPase domain	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
NTF2-like	UBA-like	1	1
PapD-like	GatB/YqeY motif	1	1
TPR-like	Metallo-dependent phosphatases	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	RING/U-box	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	FYVE/PHD zinc finger	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
PX domain	SAICAR synthase-like	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-binding domain	1	1
Actin-like ATPase domain	AF1104-like	1	1
PH domain-like	NAD kinase/diacylglycerol kinase-like	1	1
FYVE/PHD zinc finger	RNI-like	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
Serine metabolism enzymes domain	ACT-like	1	1
Acyl-CoA binding protein	Supernatant protein factor (SPF), C-terminal domain	1	1
L domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
TAZ domain	Kix domain of CBP (creb binding protein)	1	1
BAR/IMD domain-like	Cysteine-rich domain	1	1
Nucleotidylyl transferase	Class II aaRS ABD-related	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	FYVE/PHD zinc finger	1	1
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
Nucleotide-binding domain	4Fe-4S ferredoxins	1	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	1	1
Dehydroquinate synthase-like	Aminoacid dehydrogenase-like, N-terminal domain	1	1
Indigoidine synthase A-like	Ribokinase-like	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	1	1
SH2 domain	UBA-like	1	1
L domain-like	Galactose-binding domain-like	1	1
Granulin repeat	Granulin repeat	1	1
RmlC-like cupins	Protein kinase-like (PK-like)	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
ArfGap/RecO-like zinc finger	SH3-domain	1	1
SMAD/FHA domain	HIT-like	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
CCCH zinc finger	ARM repeat	1	1
Calponin-homology domain, CH-domain	PLC-like phosphodiesterases	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
WD40 repeat-like	Actin depolymerizing proteins	1	1
PH domain-like	POZ domain	1	1
WW domain	FF domain	1	1
ARID-like	FYVE/PHD zinc finger	1	1
Ribosomal protein S7	Ribosomal protein S7	1	1
ADP-ribosylation	RNI-like	1	1
alpha-helical ferredoxin	4Fe-4S ferredoxins	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	1	1
beta-sandwich domain of Sec23/24	Acyl-CoA binding protein	1	1
WWE domain	SAP domain	1	1
UBC-like	Class II aaRS ABD-related	1	1
PreATP-grasp domain	post-HMGL domain-like	1	1
Cytochrome b5-like heme/steroid binding domain	HSP20-like chaperones	1	1
TAZ domain	TAZ domain	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
ENTH/VHS domain	Clathrin adaptor appendage domain	1	1
DPP6 N-terminal domain-like	Cyclophilin-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
PH domain-like	L domain-like	1	1
Nudix	ADP-ribosylation	1	1
RING/U-box	beta-sandwich domain of Sec23/24	1	1
ENTH/VHS domain	ARM repeat	1	1
HLH, helix-loop-helix DNA-binding domain	SAM/Pointed domain	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	1	1
RCC1/BLIP-II	FYVE/PHD zinc finger	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	1	1
FYSH domain	EF-G C-terminal domain-like	1	1
WD40 repeat-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Cap-Gly domain	L domain-like	1	1
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, catalytic domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Putative DNA-binding domain	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	1	1
Ubiquitin-like	Zn-binding ribosomal proteins	1	1
Pectin lyase-like	Caspase-like	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
beta-sandwich domain of Sec23/24	A DNA-binding domain in eukaryotic transcription factors	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	1	1
(Trans)glycosidases	Six-hairpin glycosidases	1	1
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	1	1
Protein kinase-like (PK-like)	Polo-box domain	1	1
Taf5 N-terminal domain-like	WD40 repeat-like	1	1
Substrate-binding domain of HMG-CoA reductase	Protein kinase-like (PK-like)	1	1
DNase I-like	SAM/Pointed domain	1	1
SAM/Pointed domain	Bet v1-like	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
CalX-like	cAMP-binding domain-like	1	1
Galactose-binding domain-like	PH domain-like	1	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	1	1
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	1	1
Phosphoenolpyruvate/pyruvate domain	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
RNI-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
Ran binding protein zinc finger-like	BRCT domain	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
CCCH zinc finger	CHY zinc finger-like	1	1
F-box domain	L domain-like	1	1
RING/U-box	RNA-binding domain, RBD	1	1
CCCH zinc finger	SMR domain-like	1	1
RUN domain-like	PDZ domain-like	1	1
ARM repeat	Chaperone J-domain	1	1
vWA-like	Cysteine-rich domain	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
L domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	1	1
Cysteine proteinases	Calcium-dependent phosphotriesterase	1	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	1	1
p53-like transcription factors	p53-like transcription factors	1	1
Cystatin/monellin	Cystatin/monellin	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
WD40 repeat-like	Ribonuclease H-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Concanavalin A-like lectins/glucanases	1	1
RuvA domain 2-like	SH2 domain	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
GroEL apical domain-like	BAR/IMD domain-like	1	1
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	1	1
Protein kinase-like (PK-like)	CheY-like	1	1
HAD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
WW domain	RING/U-box	1	1
PX domain	GTPase activation domain, GAP	1	1
WW domain	I/LWEQ domain	1	1
MIT domain	Cysteine proteinases	1	1
Pentapeptide repeat-like	SH3-domain	1	1
BAR/IMD domain-like	I/LWEQ domain	1	1
Rudiment single hybrid motif	PurM N-terminal domain-like	1	1
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	1	1
Peptidyl-tRNA hydrolase-like	Peptidyl-tRNA hydrolase-like	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
L domain-like	NTF2-like	1	1
BAR/IMD domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Ubiquitin-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
(Phosphotyrosine protein) phosphatases II	Chaperone J-domain	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Ribulose-phoshate binding barrel	1	1
Protein kinase-like (PK-like)	Ypt/Rab-GAP domain of gyp1p	1	1
Ankyrin repeat	ARM repeat	1	1
PX domain	Phospholipase D/nuclease	1	1
RING/U-box	Ran binding protein zinc finger-like	1	1
PurS-like	PurM C-terminal domain-like	1	1
UBA-like	Thioredoxin-like	1	1
Signal recognition particle alu RNA binding heterodimer, SRP9/14	Tropomyosin	1	1
L9 N-domain-like	Ribosomal protein L9 C-domain	1	1
HR1 repeat	Protein kinase-like (PK-like)	1	1
cAMP-binding domain-like	F-box domain	1	1
Acyl-CoA N-acyltransferases (Nat)	HAD-like	1	1
Ubiquitin-like	Calcium-dependent phosphotriesterase	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1
PurS-like	PurM N-terminal domain-like	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Glucocorticoid receptor-like (DNA-binding domain)	"Winged helix" DNA-binding domain	1	1
HR1 repeat	SH3-domain	1	1
ERO1-like	ERO1-like	1	1
EF-hand	Cysteine proteinases	1	1
MFS general substrate transporter	MFS general substrate transporter	1	1
ADP-ribosylation	vWA-like	1	1
FAD/NAD(P)-binding domain	Folate-binding domain	1	1
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	EF-hand	1	1
Second domain of FERM	FAT domain of focal adhesion kinase	1	1
USP8 N-terminal domain-like	Rhodanese/Cell cycle control phosphatase	1	1
Myosin rod fragments	WD40 repeat-like	1	1
WW domain	CCCH zinc finger	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
Soluble quinoprotein glucose dehydrogenase	Galactose-binding domain-like	1	1
FYVE/PHD zinc finger	GroEL-intermediate domain like	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
P-loop containing nucleoside triphosphate hydrolases	SAP domain	1	1
Thioesterase/thiol ester dehydrase-isomerase	4'-phosphopantetheinyl transferase	1	1
Cytochrome P450	Riboflavin synthase domain-like	1	1
POZ domain	FYVE/PHD zinc finger	1	1
Ricin B-like lectins	C-type lectin-like	1	1
E set domains	I/LWEQ domain	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
DNA mismatch repair protein MutL	DNA mismatch repair protein MutL	1	1
LigT-like	Nucleotidyltransferase	1	1
Adenine nucleotide alpha hydrolases-like	Nucleotidylyl transferase	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
PH domain-like	A middle domain of Talin 1	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	ArfGap/RecO-like zinc finger	1	1
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
Nucleotide-diphospho-sugar transferases	NAD(P)-binding Rossmann-fold domains	1	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	1	1
Galactose oxidase, central domain	POZ domain	1	1
Actin-crosslinking proteins	Actin-crosslinking proteins	1	1
Transcription factor STAT-4 N-domain	p53-like transcription factors	1	1
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	1	1
I/LWEQ domain	ArfGap/RecO-like zinc finger	1	1
TAZ domain	RING/U-box	1	1
Spermadhesin, CUB domain	Ricin B-like lectins	1	1
Kix domain of CBP (creb binding protein)	RING/U-box	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
Voltage-gated potassium channels	Voltage-gated potassium channels	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
TPR-like	Cysteine proteinases	1	1
Histone-fold	Macro domain-like	1	1
PH domain-like	alpha-catenin/vinculin-like	1	1
Clc chloride channel	Clc chloride channel	1	1
TGS-like	Class II aaRS ABD-related	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Ubiquitin-like	Moesin tail domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	SH3-domain	1	1
Thiolase-like	SCP-like	1	1
FAD-linked reductases, C-terminal domain	Folate-binding domain	1	1
ACT-like	PLP-binding barrel	1	1
NAD-binding domain of HMG-CoA reductase	Protein kinase-like (PK-like)	1	1
HSP20-like chaperones	Riboflavin synthase domain-like	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	1	1
RING/U-box	ACP-like	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	1	1
RING/U-box	UBA-like	1	1
BRCT domain	Actin-like ATPase domain	1	1
Formate/glycerate dehydrogenase catalytic domain-like	DHS-like NAD/FAD-binding domain	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
SET domain	Tudor/PWWP/MBT	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Multiheme cytochromes	1	1
HMG-box	WWE domain	1	1
Calponin-homology domain, CH-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
E set domains	alpha-catenin/vinculin-like	1	1
Nucleotidylyl transferase	C-terminal domain of ProRS	1	1
ClpP/crotonase	Growth factor receptor domain	1	1
Apyrase	Apyrase	1	1
Ubiquitin-like	(Phosphotyrosine protein) phosphatases II	1	1
Saposin	SGNH hydrolase	1	1
HSP20-like chaperones	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
TrmE connector domain	P-loop containing nucleoside triphosphate hydrolases	1	1
UBA-like	Hect, E3 ligase catalytic domain	1	1
Cysteine-rich domain	CCCH zinc finger	1	1
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	1	1
beta-sandwich domain of Sec23/24	Nucleotide cyclase	1	1
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Calponin-homology domain, CH-domain	Thioredoxin-like	1	1
Regulator of G-protein signaling, RGS	PH domain-like	1	1
vWA-like	14-3-3 protein	1	1
beta-beta-alpha zinc fingers	FYVE/PHD zinc finger	1	1
Nucleic acid-binding proteins	Macro domain-like	1	1
CRAL/TRIO domain	GatB/YqeY motif	1	1
Alpha-L RNA-binding motif	Pseudouridine synthase	1	1
Family A G protein-coupled receptor-like	SAICAR synthase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	1	1
TPR-like	SET domain	1	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	1	1
NAD(P)-binding Rossmann-fold domains	DHS-like NAD/FAD-binding domain	1	1
Spermadhesin, CUB domain	Growth factor receptor domain	1	1
RuBisCo LSMT C-terminal, substrate-binding domain	Acid phosphatase/Vanadium-dependent haloperoxidase	1	1
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	1	1
BRCT domain	vWA-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	SAM/Pointed domain	1	1
Growth factor receptor domain	SH3-domain	1	1
FYVE/PHD zinc finger	Protein kinase-like (PK-like)	1	1
Myosin rod fragments	Cysteine-rich domain	1	1
EF-hand	SAM/Pointed domain	1	1
SMAD/FHA domain	Protein kinase-like (PK-like)	1	1
Cytochrome P450	Flavoproteins	1	1
Single hybrid motif	HAD-like	1	1
EPT/RTPC-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Hemopexin-like domain	SAM/Pointed domain	1	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	1	1
Domain of poly(ADP-ribose) polymerase	Actin-like ATPase domain	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
Ribosomal protein L25-like	Class II aaRS ABD-related	1	1
PKD domain	Growth factor receptor domain	1	1
Calponin-homology domain, CH-domain	GTPase activation domain, GAP	1	1
DBL homology domain (DH-domain)	SH2 domain	1	1
WW domain	Ubiquitin-like	1	1
ARM repeat	JAB1/MPN domain	1	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	1	1
Nudix	P-loop containing nucleoside triphosphate hydrolases	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
F-box domain	Quinoprotein alcohol dehydrogenase-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
cAMP-binding domain-like	RNI-like	1	1
UBC-like	Ribosomal protein S5 domain 2-like	1	1
TROVE domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Acid proteases	Saposin	1	1
Acid proteases	UBA-like	1	1
CRAL/TRIO domain	GTPase activation domain, GAP	1	1
Carbamate kinase-like	PLP-binding barrel	1	1
PH domain-like	VPS9 domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Chaperone J-domain	1	1
Tricorn protease domain 2	Quinoprotein alcohol dehydrogenase-like	1	1
Cysteine proteinases	Protein kinase-like (PK-like)	1	1
Fibronectin type III	TSP-1 type 1 repeat	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
Ubiquitin-like	FAT domain of focal adhesion kinase	1	1
Dehydroquinate synthase-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleoside hydrolase	Nucleoside hydrolase	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Thiolase-like	4'-phosphopantetheinyl transferase	1	1
PH domain-like	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	1	1
RNA-binding domain, RBD	PABC (PABP) domain	1	1
CRAL/TRIO N-terminal domain	GatB/YqeY motif	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
WD40 repeat-like	Bromodomain	1	1
Kelch motif	Growth factor receptor domain	1	1
Creatinase/prolidase N-terminal domain	Creatinase/prolidase N-terminal domain	1	1
Alkaline phosphatase-like	Alkaline phosphatase-like	1	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	1	1
FabD/lysophospholipase-like	Thiolase-like	1	1
S15/NS1 RNA-binding domain	C-terminal domain of ProRS	1	1
Actin-like ATPase domain	Nudix	1	1
FabD/lysophospholipase-like	FabD/lysophospholipase-like	1	1
WD40 repeat-like	HIT/MYND zinc finger-like	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Rap/Ran-GAP	Rap/Ran-GAP	1	1
Regulator of G-protein signaling, RGS	Cysteine-rich domain	1	1
Histone-fold	PH domain-like	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
GST C-terminal domain-like	eEF-1beta-like	1	1
Second domain of FERM	A middle domain of Talin 1	1	1
Enolase N-terminal domain-like	Enolase C-terminal domain-like	1	1
p53-like transcription factors	p53 tetramerization domain	1	1
Spermadhesin, CUB domain	PKD domain	1	1
Ribosomal protein L25-like	Class II aaRS and biotin synthetases	1	1
Periplasmic binding protein-like II	beta-sandwich domain of Sec23/24	1	1
Thioesterase/thiol ester dehydrase-isomerase	Bet v1-like	1	1
FAS1 domain	FAS1 domain	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
L domain-like	Actin depolymerizing proteins	1	1
TATA-box binding protein-like	TATA-box binding protein-like	1	1
Protein kinase-like (PK-like)	FAT domain of focal adhesion kinase	1	1
Tex N-terminal region-like	SH2 domain	1	1
Quinoprotein alcohol dehydrogenase-like	HIT/MYND zinc finger-like	1	1
RING/U-box	ADP-ribosylglycohydrolase	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
USP8 N-terminal domain-like	Cysteine proteinases	1	1
Nitrous oxide reductase, N-terminal domain	Kelch motif	1	1
RUN domain-like	Cysteine-rich domain	1	1
Oxidoreductase molybdopterin-binding domain	E set domains	1	1
SAP domain	Actin-like ATPase domain	1	1
FMN-linked oxidoreductases	FMN-linked oxidoreductases	1	1
UROD/MetE-like	UROD/MetE-like	1	1
Pentapeptide repeat-like	DPP6 N-terminal domain-like	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
GTPase activation domain, GAP	VPS9 domain	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
DNA-glycosylase	Nudix	1	1
WW domain	BAR/IMD domain-like	1	1
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
NAD(P)-binding Rossmann-fold domains	Glycerol-3-phosphate (1)-acyltransferase	1	1
ADP-ribosylation	Actin-like ATPase domain	1	1
EF-hand	Dimeric alpha+beta barrel	1	1
Cobalamin (vitamin B12)-binding domain	Methionine synthase activation domain-like	1	1
Cysteine-rich domain	PLC-like phosphodiesterases	1	1
L domain-like	HAD-like	1	1
DBL homology domain (DH-domain)	Ras GEF	1	1
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	1	1
RNI-like	PP2C-like	1	1
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	1	1
F-box domain	Ankyrin repeat	1	1
MIR domain	MIR domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Ankyrin repeat	Growth factor receptor domain	1	1
Glycerol-3-phosphate (1)-acyltransferase	beta-sandwich domain of Sec23/24	1	1
Dihydropteroate synthetase-like	Methionine synthase activation domain-like	1	1
WD40 repeat-like	Ankyrin repeat	1	1
ARM repeat	PX domain	1	1
ARID-like	Clavaminate synthase-like	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
SMAD/FHA domain	PH domain-like	1	1
DBL homology domain (DH-domain)	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	1	1
Kelch motif	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	1	1
CoA-dependent acyltransferases	ACP-like	1	1
ARM repeat	"Winged helix" DNA-binding domain	1	1
POZ domain	Cap-Gly domain	1	1
Ankyrin repeat	GTPase activation domain, GAP	1	1
FAD/NAD(P)-binding domain	Aminomethyltransferase beta-barrel domain	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
Cysteine-rich domain	Multiheme cytochromes	1	1
SMAD/FHA domain	RING/U-box	1	1
Calponin-homology domain, CH-domain	E set domains	1	1
FYVE/PHD zinc finger	Hect, E3 ligase catalytic domain	1	1
EPT/RTPC-like	Aminoacid dehydrogenase-like, N-terminal domain	1	1
FKBP-like	FKBP-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	1	1
UBA-like	SNARE fusion complex	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
Bromodomain	Tudor/PWWP/MBT	1	1
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	1	1
P-loop containing nucleoside triphosphate hydrolases	Aldolase	1	1
GAT-like domain	Clathrin adaptor appendage domain	1	1
FAD-linked reductases, C-terminal domain	EF-hand	1	1
SMAD/FHA domain	FYVE/PHD zinc finger	1	1
Phospholipase D/nuclease	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
PH domain-like	Moesin tail domain	1	1
SMAD/FHA domain	dsRNA-binding domain-like	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Class I glutamine amidotransferase-like	Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	1	1
ARM repeat	DPP6 N-terminal domain-like	1	1
HAD-like	HAD-like	1	1
WWE domain	ADP-ribosylation	1	1
Subtilisin-like	Galactose-binding domain-like	1	1
WW domain	FKBP-like	1	1
BSD domain-like	BSD domain-like	1	1
PRP4-like	WD40 repeat-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	1	1
Ankyrin repeat	TSP-1 type 1 repeat	1	1
CalX-like	alpha/beta-Hydrolases	1	1
ACT-like	Alanine racemase C-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Zn-finger domain of Sec23/24	1	1
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	Growth factor receptor domain	1	1
vWA-like	Actin-like ATPase domain	1	1
WD40 repeat-like	VHP, Villin headpiece domain	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	1	1
CCCH zinc finger	FMN-linked oxidoreductases	1	1
BEACH domain	FYVE/PHD zinc finger	1	1
PUA domain-like	eIF1-like	1	1
SH3-domain	ARM repeat	1	1
L domain-like	WW domain	1	1
SAM/Pointed domain	FYVE/PHD zinc finger	1	1
RNI-like	YbiA-like	1	1
PAH2 domain	PAH2 domain	1	1
P-loop containing nucleoside triphosphate hydrolases	ArfGap/RecO-like zinc finger	1	1
Ankyrin repeat	Second domain of FERM	1	1
CCCH zinc finger	Hect, E3 ligase catalytic domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
RNA-binding domain, RBD	R3H domain	1	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	1	1
CoA-dependent acyltransferases	Acetyl-CoA synthetase-like	1	1
Transcription factor STAT-4 N-domain	SH2 domain	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
BB1717-like	BB1717-like	1	1
CCCH zinc finger	RNA-binding domain, RBD	1	1
Domain of poly(ADP-ribose) polymerase	vWA-like	1	1
Protein kinase-like (PK-like)	Apolipoprotein A-I	1	1
DBL homology domain (DH-domain)	CAD & PB1 domains	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	1	1
Second domain of FERM	Ras GEF	1	1
HSP20-like chaperones	HCP-like	1	1
NAD kinase/diacylglycerol kinase-like	HAD-like	1	1
N-terminal domain of cbl (N-cbl)	EF-hand	1	1
Pre-PUA domain	PUA domain-like	1	1
UBA-like	XPC-binding domain	1	1
BRCT domain	14-3-3 protein	1	1
MFS general substrate transporter	Regulator of G-protein signaling, RGS	1	1
FabD/lysophospholipase-like	4'-phosphopantetheinyl transferase	1	1
EF-hand	Sm-like ribonucleoproteins	1	1
SH3-domain	RING/U-box	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Carbamate kinase-like	Carbamate kinase-like	1	1
PH domain-like	I/LWEQ domain	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
HisI-like	ALDH-like	1	1
"Winged helix" DNA-binding domain	HAD-like	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	Macro domain-like	1	1
Ubiquitin-like	Calponin-homology domain, CH-domain	1	1
Dehydroquinate synthase-like	NAD(P)-binding Rossmann-fold domains	1	1
TROVE domain-like	WD40 repeat-like	1	1
Methionine synthase domain	Methionine synthase activation domain-like	1	1
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
RUN domain-like	RUN domain-like	1	1
PheT/TilS domain	Putative DNA-binding domain	1	1
Thioesterase/thiol ester dehydrase-isomerase	SCP-like	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
SIS domain	SIS domain	1	1
RING/U-box	FabD/lysophospholipase-like	1	1
Ankyrin repeat	Ras GEF	1	1
WW domain	EF-hand	1	1
Seven-hairpin glycosidases	PA domain	1	1
Nucleotide-diphospho-sugar transferases	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
beta-sandwich domain of Sec23/24	DNase I-like	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
L domain-like	Concanavalin A-like lectins/glucanases	1	1
Phospholipase C/P1 nuclease	Integrin alpha N-terminal domain	1	1
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
RING/U-box	Cyclophilin-like	1	1
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	1	1
GAF domain-like	GAF domain-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
E set domains	AMPKBI-like	1	1
vWA-like	vWA-like	1	1
SH2 domain	Ubiquitin-like	1	1
Histone-fold	ARM repeat	1	1
Domain of poly(ADP-ribose) polymerase	14-3-3 protein	1	1
P-loop containing nucleoside triphosphate hydrolases	POZ domain	1	1
N-terminal domain of cbl (N-cbl)	SH2 domain	1	1
VPS9 domain	Ankyrin repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	Cysteine-rich domain	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
WW domain	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
(Phosphotyrosine protein) phosphatases II	ARM repeat	1	1
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	1	1
WD40 repeat-like	SNARE fusion complex	1	1
I/LWEQ domain	Calponin-homology domain, CH-domain	1	1
LEM domain	Ankyrin repeat	1	1
Dcp2 domain-like	Nudix	1	1
PH domain-like	Formin homology 2 domain (FH2 domain)	1	1
EF-hand	NAD kinase/diacylglycerol kinase-like	1	1
RNA-binding domain, RBD	SET domain	1	1
FYVE/PHD zinc finger	SH3-domain	1	1
FabD/lysophospholipase-like	NAD(P)-binding Rossmann-fold domains	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	1	1
Bet v1-like	HAD-like	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	1	1
Cu,Zn superoxide dismutase-like	SH3-domain	1	1
Ribonuclease H-like	SH2 domain	1	1
WWE domain	WWE domain	1	1
HR1 repeat	Cysteine-rich domain	1	1
Second domain of FERM	Moesin tail domain	1	1
Zinc beta-ribbon	Cyclin-like	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SET domain	1	1
SWIB/MDM2 domain	SWIB/MDM2 domain	1	1
Nucleotidyltransferase	Nucleotidyltransferase	1	1
DNA-binding protein LAG-1 (CSL)	E set domains	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
"Winged helix" DNA-binding domain	Sec7 domain	1	1
Cation efflux protein transmembrane domain-like	Cation efflux protein transmembrane domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
DNase I-like	PAP/OAS1 substrate-binding domain	1	1
HLH, helix-loop-helix DNA-binding domain	CRAL/TRIO domain	1	1
Concanavalin A-like lectins/glucanases	EF-hand	1	1
Homodimeric domain of signal transducing histidine kinase	Homodimeric domain of signal transducing histidine kinase	1	1
SET domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
Retrovirus zinc finger-like domains	HIT-like	1	1
Zn2/Cys6 DNA-binding domain	beta-sandwich domain of Sec23/24	1	1
CRAL/TRIO domain	Glutamine synthetase/guanido kinase	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
Single hybrid motif	ClpP/crotonase	1	1
NAD kinase/diacylglycerol kinase-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Rudiment single hybrid motif	Aldolase	1	1
Rudiment single hybrid motif	post-HMGL domain-like	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
Cysteine proteinases	ARM repeat	1	1
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	1	1
MIR domain	Concanavalin A-like lectins/glucanases	1	1
F-box domain	TPR-like	1	1
PX domain	PX domain	1	1
Metalloproteases ("zincins"), catalytic domain	Fibronectin type III	1	1
B-box zinc-binding domain	B-box zinc-binding domain	1	1
EF-hand	Tropomyosin	1	1
FAD-linked reductases, C-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	1	1
Carbamate kinase-like	Alanine racemase C-terminal domain-like	1	1
Aldolase	NAD(P)-binding Rossmann-fold domains	1	1
EPT/RTPC-like	NAD(P)-binding Rossmann-fold domains	1	1
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Ubiquitin-like	AN1-like Zinc finger	1	1
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	1	1
Kelch motif	Protein kinase-like (PK-like)	1	1
Bet v1-like	Regulator of G-protein signaling, RGS	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
"Winged helix" DNA-binding domain	GroEL apical domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	1	1
Cysteine proteinases	Ribonuclease H-like	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
Cysteine-rich domain	WD40 repeat-like	1	1
PH domain-like	Cullin repeat-like	1	1
UBC-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Spermadhesin, CUB domain	Spermadhesin, CUB domain	1	1
SAP domain	WGR domain-like	1	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
FYVE/PHD zinc finger	Rabenosyn-5 Rab-binding domain-like	1	1
FYVE/PHD zinc finger	SAICAR synthase-like	1	1
beta-beta-alpha zinc fingers	beta-sandwich domain of Sec23/24	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
EPT/RTPC-like	Aldolase	1	1
(Trans)glycosidases	Nucleotide-diphospho-sugar transferases	1	1
Cysteine proteinases	HIT/MYND zinc finger-like	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
Putative isomerase YbhE	Kelch motif	1	1
Glucocorticoid receptor-like (DNA-binding domain)	SH2 domain	1	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	1	1
Homeodomain-like	ARM repeat	1	1
WD40 repeat-like	Cysteine proteinases	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
MIR domain	EF-hand	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Calponin-homology domain, CH-domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	Ribulose-phoshate binding barrel	1	1
Polo-box domain	Polo-box domain	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
TRAF domain-like	Cysteine proteinases	1	1
CAD & PB1 domains	Cysteine-rich domain	1	1
BAR/IMD domain-like	HIT/MYND zinc finger-like	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Concanavalin A-like lectins/glucanases	IP3 receptor type 1 binding core, domain 2	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	1	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	1	1
"Winged helix" DNA-binding domain	Cysteine-rich domain	1	1
RNA-binding domain, RBD	ENTH/VHS domain	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
RING/U-box	I/LWEQ domain	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
DUSP-like	DUSP-like	1	1
UBC-like	YbaK/ProRS associated domain	1	1
beta-sandwich domain of Sec23/24	Ribonuclease H-like	1	1
Acyl-CoA binding protein	ClpP/crotonase	1	1
E set domains	Glycosyl hydrolase domain	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	PX domain	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	1	1
N-terminal domain of cbl (N-cbl)	RING/U-box	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	S-adenosyl-L-methionine-dependent methyltransferases	1	1
beta-sandwich domain of Sec23/24	Ankyrin repeat	1	1
p53 tetramerization domain	SAM/Pointed domain	1	1
HCP-like	GTPase activation domain, GAP	1	1
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	1	1
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	1	1
F-box domain	HIT/MYND zinc finger-like	1	1
Myosin rod fragments	Apolipoprotein A-I	1	1
Ran binding protein zinc finger-like	Ankyrin repeat	1	1
Pectin lyase-like	Family A G protein-coupled receptor-like	1	1
ARM repeat	Hect, E3 ligase catalytic domain	1	1
SH2 domain	Concanavalin A-like lectins/glucanases	1	1
Phospholipase A2, PLA2	alpha-D-mannose-specific plant lectins	1	1
GTPase activation domain, GAP	ARM repeat	1	1
FYVE/PHD zinc finger	beta-lactamase/transpeptidase-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
YjgF-like	YjgF-like	1	1
ArfGap/RecO-like zinc finger	UBA-like	1	1
DNase I-like	LigT-like	1	1
PH domain-like	E set domains	1	1
PHM/PNGase F	PHM/PNGase F	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
L domain-like	Hect, E3 ligase catalytic domain	1	1
ARM repeat	Toll/Interleukin receptor TIR domain	1	1
F-box domain	EF-hand	1	1
Apolipoprotein A-I	PH domain-like	1	1
WGR domain-like	Nucleic acid-binding proteins	1	1
RING/U-box	Calponin-homology domain, CH-domain	1	1
LeuD/IlvD-like	LeuD/IlvD-like	1	1
CHY zinc finger-like	Zinc hairpin stack	1	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	1	1
TPR-like	SH3-domain	1	1
DNase I-like	Nucleotidyltransferase	1	1
Cysteine-rich domain	Ras GEF	1	1
Ankyrin repeat	Galactose-binding domain-like	1	1
EF-hand	FAD-linked oxidoreductase	1	1
RNI-like	Fibronectin type III	1	1
Calcium ATPase, transmembrane domain M	Calcium ATPase, transmembrane domain M	1	1
Metallo-dependent phosphatases	Growth factor receptor domain	1	1
ValRS/IleRS/LeuRS editing domain	ValRS/IleRS/LeuRS editing domain	1	1
Ubiquitin-like	BAG domain	1	1
Homocysteine S-methyltransferase	Methionine synthase activation domain-like	1	1
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	1	1
The spindle assembly checkpoint protein mad2	FYVE/PHD zinc finger	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
PapD-like	Glutamine synthetase/guanido kinase	1	1
Ricin B-like lectins	Kringle-like	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	UBA-like	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
BB1717-like	UBA-like	1	1
DBL homology domain (DH-domain)	Glucocorticoid receptor-like (DNA-binding domain)	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
E set domains	TPR-like	1	1
SWIB/MDM2 domain	eIF1-like	1	1
Second domain of FERM	(Phosphotyrosine protein) phosphatases II	1	1
His-Me finger endonucleases	HIT/MYND zinc finger-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
Apolipoprotein A-I	Cysteine-rich domain	1	1
P-loop containing nucleoside triphosphate hydrolases	FabD/lysophospholipase-like	1	1
Cysteine-rich domain	Hect, E3 ligase catalytic domain	1	1
LigT-like	PAP/OAS1 substrate-binding domain	1	1
NAD kinase/diacylglycerol kinase-like	SAM/Pointed domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
ISP domain	FAD/NAD(P)-binding domain	1	1
I/LWEQ domain	I/LWEQ domain	1	1
RmlC-like cupins	ADP-ribosylation	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
Pseudouridine synthase	PUA domain-like	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
PHM/PNGase F	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
SAICAR synthase-like	SAICAR synthase-like	1	1
CHY zinc finger-like	RING/U-box	1	1
DAK1/DegV-like	DhaL-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
BAR/IMD domain-like	HR1 repeat	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
Nitrous oxide reductase, N-terminal domain	Putative isomerase YbhE	1	1
all-alpha NTP pyrophosphatases	ALDH-like	1	1
PRTase-like	PRTase-like	1	1
F-box domain	beta-sandwich domain of Sec23/24	1	1
Ubiquitin-like	vWA-like	1	1
Ankyrin repeat	Chaperone J-domain	1	1
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	1	1
DNase I-like	RNA-binding domain, RBD	1	1
"Winged helix" DNA-binding domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
PH domain-like	FAT domain of focal adhesion kinase	1	1
L domain-like	Calponin-homology domain, CH-domain	1	1
FMN-linked oxidoreductases	4Fe-4S ferredoxins	1	1
FAD/NAD(P)-binding domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
Hypothetical protein AF0491, middle domain	EF-G C-terminal domain-like	1	1
Phosphofructokinase	Phosphofructokinase	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
RibA-like	Dihydrofolate reductase-like	1	1
Dehydroquinate synthase-like	EPT/RTPC-like	1	1
F-box domain	F-box domain	1	1
PX domain	Ubiquitin-like	1	1
Ubiquitin-like	Acid proteases	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
CRAL/TRIO N-terminal domain	Glutamine synthetase/guanido kinase	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	1	1
E set domains	Thioredoxin-like	1	1
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	1	1
PX domain	L domain-like	1	1
Rap/Ran-GAP	PDZ domain-like	1	1
GroEL equatorial domain-like	BAR/IMD domain-like	1	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
TPR-like	RNI-like	1	1
Chaperone J-domain	CSL zinc finger	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Hedgehog/intein (Hint) domain	Ribonuclease H-like	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
Thioesterase/thiol ester dehydrase-isomerase	Thiolase-like	1	1
HLH, helix-loop-helix DNA-binding domain	FYVE/PHD zinc finger	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
EF-hand	I/LWEQ domain	1	1
Cytochrome P450	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
CAD & PB1 domains	PDZ domain-like	1	1
FYVE/PHD zinc finger	"Winged helix" DNA-binding domain	1	1
CoA-dependent acyltransferases	NAD(P)-binding Rossmann-fold domains	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	1	1
Heme-dependent catalase-like	Class I glutamine amidotransferase-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
PDZ domain-like	Protein kinase-like (PK-like)	1	1
Galactose-binding domain-like	Kelch motif	1	1
Second domain of FERM	Protein kinase-like (PK-like)	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
Protein kinase-like (PK-like)	Chaperone J-domain	1	1
"Winged helix" DNA-binding domain	Rap/Ran-GAP	1	1
CalX-like	Family A G protein-coupled receptor-like	1	1
"Winged helix" DNA-binding domain	NAD kinase/diacylglycerol kinase-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	HAD-like	1	1
Periplasmic binding protein-like I	Periplasmic binding protein-like I	1	1
SAP domain	RNA-binding domain, RBD	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	1	1
SAP domain	PH domain-like	1	1
TPR-like	RNA-binding domain, RBD	1	1
P-loop containing nucleoside triphosphate hydrolases	Rap/Ran-GAP	1	1
Pectin lyase-like	Growth factor receptor domain	1	1
Nucleotidylyl transferase	Class II aaRS and biotin synthetases	1	1
PUG domain-like	Ubiquitin-like	1	1
DBL homology domain (DH-domain)	ArfGap/RecO-like zinc finger	1	1
cAMP-binding domain-like	alpha/beta-Hydrolases	1	1
PreATP-grasp domain	PurM N-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Aldolase	1	1
GST C-terminal domain-like	C-terminal domain of ProRS	1	1
Homeodomain-like	JAB1/MPN domain	1	1
Dihydropteroate synthetase-like	Cobalamin (vitamin B12)-binding domain	1	1
DNase I-like	GTPase activation domain, GAP	1	1
F-box domain	DPP6 N-terminal domain-like	1	1
HIT/MYND zinc finger-like	Ankyrin repeat	1	1
Ubiquitin-like	alpha-catenin/vinculin-like	1	1
Protein kinase-like (PK-like)	Mitochondrial carrier	1	1
Caspase-like	HCP-like	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
Protease propeptides/inhibitors	Galactose-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	1	1
ENTH/VHS domain	I/LWEQ domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Regulator of G-protein signaling, RGS	1	1
Rudiment single hybrid motif	PurM C-terminal domain-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
Macro domain-like	Macro domain-like	1	1
Methylglyoxal synthase-like	Metallo-dependent hydrolases	1	1
ADP-ribosylation	YbiA-like	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
Ricin B-like lectins	PKD domain	1	1
R3H domain	Ribonuclease H-like	1	1
Histone-fold	DBL homology domain (DH-domain)	1	1
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	1	1
RNase III domain-like	dsRNA-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	RGC domain-like	1	1
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	1	1
GTPase activation domain, GAP	HIT/MYND zinc finger-like	1	1
Cysteine-rich domain	WW domain	1	1
Metallo-dependent phosphatases	Smc hinge domain	1	1
WGR domain-like	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	1	1
Zinc hairpin stack	RING/U-box	1	1