Domain combination pairs in Spizellomyces punctatus DAOM BR117

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1612 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	109	44
TPR-like	TPR-like	32	18
RNA-binding domain, RBD	RNA-binding domain, RBD	29	19
HAD-like	Calcium ATPase, transmembrane domain M	28	8
Actin-like ATPase domain	Actin-like ATPase domain	27	11
Calcium ATPase, transduction domain A	HAD-like	27	7
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	27	7
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	26	9
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	25	23
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	25	6
HAD-like	Metal cation-transporting ATPase, ATP-binding domain N	25	6
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	25	6
ARM repeat	ARM repeat	24	20
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	24	9
Ribonuclease H-like	DNA/RNA polymerases	24	11
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	24	22
Homodimeric domain of signal transducing histidine kinase	CheY-like	23	21
WD40 repeat-like	WD40 repeat-like	23	14
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	22	15
GroES-like	NAD(P)-binding Rossmann-fold domains	22	3
F-box domain	RNI-like	19	9
Ribonuclease H-like	Chromo domain-like	18	7
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	17	10
ABC transporter transmembrane region	ABC transporter transmembrane region	17	6
F-box domain	WD40 repeat-like	16	7
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	15	6
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	15	5
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	14	7
CheY-like	PYP-like sensor domain (PAS domain)	14	13
CBS-domain pair	CBS-domain pair	13	5
Homodimeric domain of signal transducing histidine kinase	PYP-like sensor domain (PAS domain)	13	12
Cyclin-like	Cyclin-like	13	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	PYP-like sensor domain (PAS domain)	13	12
ARM repeat	Protein kinase-like (PK-like)	13	11
DNA/RNA polymerases	Chromo domain-like	12	4
CheY-like	CheY-like	11	11
Retrovirus zinc finger-like domains	Ribonuclease H-like	11	6
Acetyl-CoA synthetase-like	ACP-like	11	11
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	11	8
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	11	10
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	11	5
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	11	7
cAMP-binding domain-like	cAMP-binding domain-like	11	7
Thioredoxin-like	GST C-terminal domain-like	11	3
DBL homology domain (DH-domain)	PH domain-like	11	10
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	10	2
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	10	9
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	9	6
Thiolase-like	Thiolase-like	9	2
HCP-like	HCP-like	9	7
GroEL equatorial domain-like	GroEL apical domain-like	9	3
Homeodomain-like	Homeodomain-like	9	8
Protein kinase-like (PK-like)	KA1-like	9	4
GroEL-intermediate domain like	GroEL apical domain-like	9	3
GroEL equatorial domain-like	GroEL-intermediate domain like	8	2
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	8	3
CoA-dependent acyltransferases	CoA-dependent acyltransferases	8	6
UBA-like	Ubiquitin-like	8	7
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	8	7
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	8	7
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	3
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	3
WD40 repeat-like	ARM repeat	8	8
DNA/RNA polymerases	DNA/RNA polymerases	8	1
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	7	5
Kelch motif	SH3-domain	7	5
(Trans)glycosidases	Glycosyl hydrolase domain	7	6
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	7	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	7	5
RING/U-box	RING/U-box	7	7
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	7	5
BAR/IMD domain-like	SH3-domain	7	5
SH3-domain	SH3-domain	7	7
Translation proteins	EF-G C-terminal domain-like	7	5
RNI-like	RNI-like	7	6
EF-G C-terminal domain-like	EF-G C-terminal domain-like	7	5
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	7	7
PreATP-grasp domain	Rudiment single hybrid motif	7	6
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	7	5
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	7	5
Nucleic acid-binding proteins	Nucleic acid-binding proteins	7	7
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	7	4
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	6	2
DBL homology domain (DH-domain)	SH3-domain	6	6
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	6	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	6	5
SH3-domain	PH domain-like	6	6
EF-hand	EF-hand	6	6
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	6	6
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	6	4
BAR/IMD domain-like	PH domain-like	6	5
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	6	5
Ubiquitin-like	Ubiquitin-like	6	6
Actin depolymerizing proteins	Actin depolymerizing proteins	6	6
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	6	4
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	6	2
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	6	6
PAZ domain	Ribonuclease H-like	6	2
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	6	5
ACP-like	ACP-like	6	6
BAR/IMD domain-like	GTPase activation domain, GAP	6	5
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	6	4
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	6	5
ClpP/crotonase	ClpP/crotonase	6	4
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	6	6
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	6	3
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	6	5
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	6	4
Protease propeptides/inhibitors	Subtilisin-like	6	4
FYVE/PHD zinc finger	FYVE/PHD zinc finger	5	5
PH domain-like	PH domain-like	5	5
CCCH zinc finger	CCCH zinc finger	5	5
SH3-domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	5	4
CoA-dependent acyltransferases	ACP-like	5	5
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	5	4
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	5	1
CBD9-like	Cytochrome b5-like heme/steroid binding domain	5	4
CBD9-like	Riboflavin synthase domain-like	5	4
Cullin homology domain	"Winged helix" DNA-binding domain	5	4
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	5	4
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	5	4
Nucleotide cyclase	Nucleotide cyclase	5	4
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	5	1
Thioredoxin-like	Thioredoxin-like	5	4
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	5	3
Chromo domain-like	Chromo domain-like	5	5
Riboflavin synthase domain-like	SH3-domain	5	4
Cytochrome b5-like heme/steroid binding domain	SH3-domain	5	4
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	5	4
Nucleotide-diphospho-sugar transferases	DEK C-terminal domain	5	3
Ubiquitin-like	PH domain-like	5	5
Rudiment single hybrid motif	Single hybrid motif	5	4
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	5	4
GAF domain-like	PYP-like sensor domain (PAS domain)	5	5
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	5	2
CBD9-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	5	4
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	5	4
WW domain	WW domain	5	5
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	5	3
CoA-dependent acyltransferases	Acetyl-CoA synthetase-like	5	5
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	5	4
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	5	3
Translation proteins SH3-like domain	Nucleic acid-binding proteins	5	5
Translation proteins	Ribosomal protein S5 domain 2-like	5	4
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	5	5
ARM repeat	Clathrin adaptor appendage domain	5	3
PreATP-grasp domain	Single hybrid motif	5	4
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	5	5
Voltage-gated potassium channels	cAMP-binding domain-like	5	2
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
GAF domain-like	CheY-like	4	4
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	4	3
Cytochrome b5-like heme/steroid binding domain	Nucleotide-diphospho-sugar transferases	4	3
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	4	3
Aconitase iron-sulfur domain	LeuD/IlvD-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	4
Clc chloride channel	CBS-domain pair	4	4
Periplasmic binding protein-like I	PH domain-like	4	2
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	4
CBD9-like	SH3-domain	4	3
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	4	4
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	4	2
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	3
Kelch motif	Kelch motif	4	4
P-loop containing nucleoside triphosphate hydrolases	Chromo domain-like	4	4
Protein kinase-like (PK-like)	PH domain-like	4	4
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	4	3
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	4	4
Flavoproteins	Riboflavin synthase domain-like	4	4
Cytochrome b5-like heme/steroid binding domain	Acyl-CoA dehydrogenase NM domain-like	4	2
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	4	4
Cullin repeat-like	Cullin homology domain	4	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	4	3
UBA-like	UBA-like	4	4
ENTH/VHS domain	GAT-like domain	4	4
Cupredoxins	Cupredoxins	4	4
RING/U-box	Cysteine proteinases	4	4
Cullin repeat-like	"Winged helix" DNA-binding domain	4	3
P-loop containing nucleoside triphosphate hydrolases	Nucleotide-diphospho-sugar transferases	4	2
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	4	3
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	4	2
Cytochrome b5-like heme/steroid binding domain	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	4	3
MFS general substrate transporter	MFS general substrate transporter	4	4
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	4	2
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	4	2
PH domain-like	GTPase activation domain, GAP	4	3
Trypsin-like serine proteases	PDZ domain-like	4	4
L domain-like	L domain-like	4	4
P-loop containing nucleoside triphosphate hydrolases	DEK C-terminal domain	4	2
GAF domain-like	GAF domain-like	4	4
ACT-like	ACT-like	4	4
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	4	3
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	3	1
beta-sandwich domain of Sec23/24	Zn-finger domain of Sec23/24	3	2
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	3	2
Homeodomain-like	RING/U-box	3	2
HIT/MYND zinc finger-like	SET domain	3	2
Mitochondrial carrier	EF-hand	3	3
Cytochrome b5-like heme/steroid binding domain	Oxidoreductase molybdopterin-binding domain	3	3
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
beta-sandwich domain of Sec23/24	vWA-like	3	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	3	2
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	3	3
Pectin lyase-like	Pectin lyase-like	3	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Cysteine-rich domain	3	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	3	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	3	3
NAD(P)-binding Rossmann-fold domains	Tetrapyrrole methylase	3	3
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
FAS1 domain	FAS1 domain	3	1
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	3	2
PX domain	BAR/IMD domain-like	3	1
E set domains	E set domains	3	2
PYP-like sensor domain (PAS domain)	Glucocorticoid receptor-like (DNA-binding domain)	3	2
Galactose mutarotase-like	Glycosyl hydrolase domain	3	3
vWA-like	Helical domain of Sec23/24	3	2
Bet v1-like	Bet v1-like	3	3
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	3	2
Sec63 N-terminal domain-like	E set domains	3	3
Galactose mutarotase-like	(Trans)glycosidases	3	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	3	3
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	3	3
Ribosomal L27 protein-like	Nucleic acid-binding proteins	3	2
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	3	3
Homodimeric domain of signal transducing histidine kinase	Homodimeric domain of signal transducing histidine kinase	3	3
ARM repeat	PH domain-like	3	3
TPR-like	Chaperone J-domain	3	3
HR1 repeat	Cysteine-rich domain	3	3
Ribonuclease H-like	Ribonuclease H-like	3	3
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	3	3
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	3	2
Retrovirus zinc finger-like domains	DNA/RNA polymerases	3	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	3	3
ADC-like	Cdc48 domain 2-like	3	2
SMAD/FHA domain	Protein kinase-like (PK-like)	3	3
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	3	2
F-box domain	Quinoprotein alcohol dehydrogenase-like	3	3
Bromodomain	Bromodomain	3	3
UDP-Glycosyltransferase/glycogen phosphorylase	Nucleotide-diphospho-sugar transferases	3	2
GAF domain-like	Nucleotide cyclase	3	3
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	3	3
FKBP-like	TPR-like	3	3
BRCT domain	BRCT domain	3	3
ARM repeat	Subdomain of clathrin and coatomer appendage domain	3	2
ACP-like	NAD(P)-binding Rossmann-fold domains	3	3
Galactose oxidase, central domain	E set domains	3	1
PH domain-like	Ankyrin repeat	3	3
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	3	2
L domain-like	DBL homology domain (DH-domain)	3	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	3	3
RNase III domain-like	RNase III domain-like	3	2
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	3	3
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	3	2
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	3	2
Cysteine-rich domain	Cysteine-rich domain	3	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	3	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	3	2
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	3	3
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	3	2
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	3	1
E set domains	(Trans)glycosidases	3	3
Single hybrid motif	CoA-dependent acyltransferases	3	2
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	3	3
TPR-like	ARM repeat	3	3
Oxidoreductase molybdopterin-binding domain	E set domains	3	3
WD40 repeat-like	TPR-like	3	3
ARM repeat	Formin homology 2 domain (FH2 domain)	3	2
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	1
Regulator of G-protein signaling, RGS	PX domain	3	3
Cysteine-rich domain	Protein kinase-like (PK-like)	3	3
Cytochrome b5-like heme/steroid binding domain	DEK C-terminal domain	3	2
SH3-domain	PX domain	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	3	3
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	3	2
TPR-like	HCP-like	3	3
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	3	3
(Trans)glycosidases	Chitinase insertion domain	3	3
SMAD/FHA domain	RING/U-box	3	2
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
PK beta-barrel domain-like	PK C-terminal domain-like	3	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	3
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	3	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	3	2
Cytochrome b5-like heme/steroid binding domain	E set domains	3	3
SNARE fusion complex	SNARE fusion complex	3	1
ADC-like	P-loop containing nucleoside triphosphate hydrolases	3	2
Zn-finger domain of Sec23/24	vWA-like	3	2
Sec7 domain	ARM repeat	3	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	3	2
GINS helical bundle-like	PriA/YqbF domain	3	2
Trypsin-like serine proteases	Trypsin-like serine proteases	3	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	3	2
SNARE-like	SNARE fusion complex	3	3
PDZ domain-like	PDZ domain-like	3	3
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	3	3
(Trans)glycosidases	(Trans)glycosidases	2	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	2	2
Ubiquitin-like	Second domain of FERM	2	2
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	2
Zinc beta-ribbon	Cyclin-like	2	2
Single hybrid motif	ClpP/crotonase	2	2
PH domain-like	PX domain	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	2	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	2	2
UBA-like	Thioredoxin-like	2	2
ISP domain	Bet v1-like	2	2
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	2	2
TPR-like	HSP20-like chaperones	2	2
Tryptophan synthase beta subunit-like PLP-dependent enzymes	CBS-domain pair	2	2
WD40 repeat-like	DPP6 N-terminal domain-like	2	2
FYVE/PHD zinc finger	Clavaminate synthase-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Ribonuclease H-like	2	2
Heme-dependent peroxidases	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	2
ISP domain	FAD/NAD(P)-binding domain	2	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	2	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	2	2
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
E set domains	Glycosyl hydrolase domain	2	2
Subtilisin-like	PA domain	2	2
RING/U-box	WD40 repeat-like	2	1
S-adenosyl-L-methionine-dependent methyltransferases	P-loop containing nucleoside triphosphate hydrolases	2	2
RING/U-box	TRAF domain-like	2	2
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	2	2
Subtilisin-like	Galactose-binding domain-like	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	2	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	2	2
ARID-like	ARM repeat	2	2
CHY zinc finger-like	Zinc hairpin stack	2	1
Ankyrin repeat	Ankyrin repeat	2	1
Chaperone J-domain	Homeodomain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	2	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	2	2
S-adenosyl-L-methionine-dependent methyltransferases	SET domain	2	1
Second domain of FERM	PH domain-like	2	2
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	2	2
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	2	2
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	2	2
HR1 repeat	Protein kinase-like (PK-like)	2	2
alpha/beta-Hydrolases	Ferritin-like	2	1
PH domain-like	EF-hand	2	2
Ubiquitin-like	Zn-binding ribosomal proteins	2	1
WD40 repeat-like	PH domain-like	2	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	2	2
PUA domain-like	Ribosomal protein S5 domain 2-like	2	1
WW domain	FF domain	2	2
Ankyrin repeat	PLC-like phosphodiesterases	2	1
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	2	2
FAD/NAD(P)-binding domain	EF-hand	2	2
vWA-like	SPOC domain-like	2	2
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	2	2
CoA-dependent acyltransferases	alpha/beta-Hydrolases	2	2
HMA, heavy metal-associated domain	HAD-like	2	2
BRCT domain	ADP-ribosylation	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	2
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	2	2
Homeodomain-like	JAB1/MPN domain	2	2
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	2	2
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	2	2
Restriction endonuclease-like	RuvA domain 2-like	2	2
Nucleotidylyl transferase	Nucleic acid-binding proteins	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	2	1
"Winged helix" DNA-binding domain	E set domains	2	2
Surp module (SWAP domain)	Surp module (SWAP domain)	2	2
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	2	1
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	2
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	2	2
Nucleotide cyclase	P-loop containing nucleoside triphosphate hydrolases	2	1
SH3-domain	SAM/Pointed domain	2	2
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	2	2
Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	NAD(P)-binding Rossmann-fold domains	2	1
WD40 repeat-like	Putative isomerase YbhE	2	2
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	2	2
Siroheme synthase middle domains-like	Tetrapyrrole methylase	2	2
NAD(P)-binding Rossmann-fold domains	Thiolase-like	2	2
TPR-like	RING/U-box	2	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	2	1
PX domain	CAD & PB1 domains	2	2
SH3-domain	Ubiquitin-like	2	2
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	2	1
PH domain-like	"Winged helix" DNA-binding domain	2	2
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Zinc hairpin stack	RING/U-box	2	1
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	2	1
DNA-binding domain of Mlu1-box binding protein MBP1	Ankyrin repeat	2	2
Retrovirus zinc finger-like domains	Chromo domain-like	2	1
Thioredoxin-like	Ubiquitin-like	2	2
Heme-dependent peroxidases	Riboflavin synthase domain-like	2	2
NAD(P)-binding Rossmann-fold domains	Siroheme synthase middle domains-like	2	2
CBS-domain pair	CAD & PB1 domains	2	1
Acetyl-CoA synthetase-like	alpha/beta-Hydrolases	2	2
GTPase activation domain, GAP	RGC domain-like	2	2
Heme-dependent peroxidases	CBD9-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	2	2
ArfGap/RecO-like zinc finger	Ankyrin repeat	2	2
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	2	1
Fibronectin type III	Fibronectin type III	2	2
PA domain	RING/U-box	2	2
RNA-binding domain, RBD	ENTH/VHS domain	2	2
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	2	2
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	2	1
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	2	2
PurM N-terminal domain-like	PurM C-terminal domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	beta-beta-alpha zinc fingers	2	2
Actin depolymerizing proteins	PH domain-like	2	2
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	2	2
SAM/Pointed domain	Protein kinase-like (PK-like)	2	2
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	2	2
Ypt/Rab-GAP domain of gyp1p	EF-hand	2	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	2
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	2	1
FF domain	FF domain	2	2
Ubiquitin-like	Cysteine proteinases	2	2
EF-hand	Calponin-homology domain, CH-domain	2	2
BRCT domain	WGR domain-like	2	2
Cysteine-rich domain	PH domain-like	2	2
WGR domain-like	ADP-ribosylation	2	2
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	2
Phospholipase D/nuclease	Phospholipase D/nuclease	2	2
FabD/lysophospholipase-like	NAD(P)-binding Rossmann-fold domains	2	2
F-box domain	Putative isomerase YbhE	2	2
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	2	2
PH domain-like	WW domain	2	2
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	2	2
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	2	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	2	2
t-snare proteins	SNARE fusion complex	2	1
Periplasmic binding protein-like II	ACT-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	2	2
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	2	2
PsbU/PolX domain-like	Nucleotidyltransferase	2	2
Acetyl-CoA synthetase-like	NAD(P)-binding Rossmann-fold domains	2	2
SH3-domain	EF-hand	2	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	2	1
E set domains	Riboflavin synthase domain-like	2	2
Rudiment single hybrid motif	ClpP/crotonase	2	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	2	1
Heme-dependent catalase-like	Class I glutamine amidotransferase-like	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	2	2
CCCH zinc finger	RNA-binding domain, RBD	2	2
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	2	2
Ubiquitin-like	AN1-like Zinc finger	2	2
PH domain-like	ArfGap/RecO-like zinc finger	2	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	2	2
"Winged helix" DNA-binding domain	GTPase activation domain, GAP	2	2
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
CHY zinc finger-like	RING/U-box	2	1
Succinyl-CoA synthetase domains	NAD(P)-binding Rossmann-fold domains	2	2
POZ domain	POZ domain	2	2
TRAF domain-like	TRAF domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	E set domains	2	2
Protease propeptides/inhibitors	Galactose-binding domain-like	2	2
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	2	2
ARM repeat	Rap/Ran-GAP	2	1
P-loop containing nucleoside triphosphate hydrolases	Cytochrome b5-like heme/steroid binding domain	2	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	2
PreATP-grasp domain	Methylglyoxal synthase-like	2	2
cAMP-binding domain-like	RNI-like	2	2
BRCT domain	Homeodomain-like	2	2
HR1 repeat	HR1 repeat	2	2
Protease propeptides/inhibitors	Zn-dependent exopeptidases	2	1
F-box domain	Clavaminate synthase-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	2	2
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	2	2
Glucocorticoid receptor-like (DNA-binding domain)	GTPase activation domain, GAP	2	2
Translational machinery components	L30e-like	2	2
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	2	2
UBC-like	Endosomal sorting complex assembly domain	2	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	2	1
WW domain	GTPase activation domain, GAP	2	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	2	1
POZ domain	Skp1 dimerisation domain-like	2	1
Heme-dependent peroxidases	Cytochrome b5-like heme/steroid binding domain	2	2
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	2	2
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
WGR domain-like	Domain of poly(ADP-ribose) polymerase	2	2
FabD/lysophospholipase-like	Thiolase-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	1
Cap-Gly domain	Ubiquitin-like	2	2
ARM repeat	Hect, E3 ligase catalytic domain	2	2
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	2
PreATP-grasp domain	PreATP-grasp domain	2	2
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	2	2
PH domain-like	Oxysterol-binding protein-like	2	2
ISP transmembrane anchor	ISP domain	2	1
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	2	2
BAR/IMD domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	2	2
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	2	2
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	2
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	2	2
BAR/IMD domain-like	Ankyrin repeat	2	2
BAR/IMD domain-like	"Winged helix" DNA-binding domain	2	2
ACP-like	Trimeric LpxA-like enzymes	2	2
TPR-like	PIN domain-like	2	1
Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	GroES-like	2	1
Ribosomal protein L6	Ribosomal protein L6	2	2
PreATP-grasp domain	ClpP/crotonase	2	2
Sec7 domain	PH domain-like	2	2
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	2	1
Protein kinase-like (PK-like)	TPR-like	2	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	2	1
ACP-like	alpha/beta-Hydrolases	2	2
ARM repeat	PYP-like sensor domain (PAS domain)	2	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	2	2
SH3-domain	WW domain	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	2	2
Translation proteins	Initiation factor IF2/eIF5b, domain 3	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	2
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	2	1
ARM repeat	Concanavalin A-like lectins/glucanases	2	2
dsRNA-binding domain-like	dsRNA-binding domain-like	2	2
RNA-binding domain, RBD	Cyclophilin-like	2	2
Retrovirus zinc finger-like domains	WD40 repeat-like	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Dihydropteroate synthetase-like	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
Spermadhesin, CUB domain	L domain-like	1	1
(Phosphotyrosine protein) phosphatases II	UBA-like	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	1	1
His-Me finger endonucleases	His-Me finger endonucleases	1	1
FYVE/PHD zinc finger	SAICAR synthase-like	1	1
PX domain	SNARE fusion complex	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
EF-hand	Sm-like ribonucleoproteins	1	1
PLP-dependent transferases	DEK C-terminal domain	1	1
SCP-like	SCP-like	1	1
SWIB/MDM2 domain	eIF1-like	1	1
HMG-box	DEK C-terminal domain	1	1
Homeodomain-like	Mitochondrial carrier	1	1
Tricorn protease domain 2	WD40 repeat-like	1	1
Peptidyl-tRNA hydrolase-like	Peptidyl-tRNA hydrolase-like	1	1
ARID-like	Clavaminate synthase-like	1	1
Inosine monophosphate dehydrogenase (IMPDH)	Thiolase-like	1	1
WD40 repeat-like	CCCH zinc finger	1	1
HIT/MYND zinc finger-like	RNA-binding domain, RBD	1	1
Growth factor receptor domain	Integrin alpha N-terminal domain	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Inhibitor of apoptosis (IAP) repeat	Inhibitor of apoptosis (IAP) repeat	1	1
Dihydropteroate synthetase-like	Methionine synthase domain	1	1
FKBP-like	Protein kinase-like (PK-like)	1	1
SpoIIaa-like	cAMP-binding domain-like	1	1
Cytochrome P450	Riboflavin synthase domain-like	1	1
Dihydropteroate synthetase-like	Methionine synthase activation domain-like	1	1
Galactose oxidase, central domain	HSP90 C-terminal domain	1	1
Class I glutamine amidotransferase-like	ADC synthase	1	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	1	1
Translation proteins SH3-like domain	Fumarate reductase respiratory complex transmembrane subunits	1	1
Ubiquitin-like	I/LWEQ domain	1	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	EF-hand	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	1	1
Homeodomain-like	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Dcp2 domain-like	Nudix	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	1	1
RNA-binding domain, RBD	PABC (PABP) domain	1	1
Bet v1-like	SH3-domain	1	1
Galactose-binding domain-like	Ribosomal protein S5 domain 2-like	1	1
ISP domain	SH3-domain	1	1
Fibronectin type III	Integrin alpha N-terminal domain	1	1
Inosine monophosphate dehydrogenase (IMPDH)	Thioesterase/thiol ester dehydrase-isomerase	1	1
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	1	1
B-box zinc-binding domain	TRAF domain-like	1	1
Ankyrin repeat	FYVE/PHD zinc finger	1	1
Osmotin, thaumatin-like protein	(Trans)glycosidases	1	1
F-box domain	Putative DNA-binding domain	1	1
NAD(P)-binding Rossmann-fold domains	ACT-like	1	1
Calponin-homology domain, CH-domain	PH domain-like	1	1
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	1	1
Methyl-accepting chemotaxis protein (MCP) signaling domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	1	1
Nucleotidylyl transferase	P-loop containing nucleoside triphosphate hydrolases	1	1
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	1	1
FAD/NAD(P)-binding domain	Nitrite/Sulfite reductase N-terminal domain-like	1	1
HisI-like	ALDH-like	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	1	1
Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain	ARM repeat	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
Nucleic acid-binding proteins	Chaperone J-domain	1	1
FAD/NAD(P)-binding domain	NAD(P)-binding Rossmann-fold domains	1	1
DBL homology domain (DH-domain)	GTPase activation domain, GAP	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Cytochrome b5-like heme/steroid binding domain	1	1
Bet v1-like	Supernatant protein factor (SPF), C-terminal domain	1	1
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	1	1
DAK1/DegV-like	DhaL-like	1	1
Concanavalin A-like lectins/glucanases	PH domain-like	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
Dehydroquinate synthase-like	Aminoacid dehydrogenase-like, N-terminal domain	1	1
Ribosomal protein L25-like	Nucleic acid-binding proteins	1	1
Nucleic acid-binding proteins	DnaJ/Hsp40 cysteine-rich domain	1	1
Methionine synthase domain	Cobalamin (vitamin B12)-binding domain	1	1
Second domain of FERM	I/LWEQ domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Urease, beta-subunit	Metallo-dependent hydrolases	1	1
F-box domain	RCC1/BLIP-II	1	1
HAD-like	Nucleotide-diphospho-sugar transferases	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
DNA clamp	DNA clamp	1	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	1	1
Ribonuclease H-like	RNA-binding domain, RBD	1	1
FAD/NAD(P)-binding domain	ACP-like	1	1
NAD(P)-binding Rossmann-fold domains	SCP-like	1	1
L30e-like	alpha/beta knot	1	1
RCC1/BLIP-II	POZ domain	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
PRTase-like	PRTase-like	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
RNI-like	GAT-like domain	1	1
Carbamate kinase-like	ACT-like	1	1
Acetyl-CoA synthetase-like	FAD/NAD(P)-binding domain	1	1
PH domain-like	HMG-box	1	1
L domain-like	Nucleotide cyclase	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
Pre-PUA domain	PUA domain-like	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
UBA-like	Formin homology 2 domain (FH2 domain)	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	UBA-like	1	1
Tudor/PWWP/MBT	BRCT domain	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
PH domain-like	PLC-like phosphodiesterases	1	1
Inosine monophosphate dehydrogenase (IMPDH)	NAD(P)-binding Rossmann-fold domains	1	1
HIT-like	HIT-like	1	1
SMAD/FHA domain	HIT-like	1	1
TPR-like	GAF domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
ENTH/VHS domain	Clathrin adaptor appendage domain	1	1
A middle domain of Talin 1	alpha-catenin/vinculin-like	1	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	1	1
Hypothetical protein YjbJ	Hypothetical protein YjbJ	1	1
Protein kinase-like (PK-like)	GAF domain-like	1	1
(Trans)glycosidases	DHS-like NAD/FAD-binding domain	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
SMAD/FHA domain	"Winged helix" DNA-binding domain	1	1
Arginase/deacetylase	SMAD/FHA domain	1	1
"Winged helix" DNA-binding domain	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Family A G protein-coupled receptor-like	Protease propeptides/inhibitors	1	1
SMAD/FHA domain	SMAD/FHA domain	1	1
Kringle-like	Integrin alpha N-terminal domain	1	1
ARM repeat	Integrin alpha N-terminal domain	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
all-alpha NTP pyrophosphatases	ALDH-like	1	1
Second domain of FERM	A middle domain of Talin 1	1	1
dsRNA-binding domain-like	UBC-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Flavoproteins	1	1
TPR-like	Metallo-dependent phosphatases	1	1
Glutaminase/Asparaginase	Ankyrin repeat	1	1
BRCT domain	Protein kinase-like (PK-like)	1	1
HAMP domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Actin-like ATPase domain	AF1104-like	1	1
Ubiquitin-like	alpha-catenin/vinculin-like	1	1
TK C-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Doublecortin (DC)	Doublecortin (DC)	1	1
HisI-like	all-alpha NTP pyrophosphatases	1	1
Calcium ATPase, transmembrane domain M	Calcium ATPase, transmembrane domain M	1	1
Urease, gamma-subunit	Urease, beta-subunit	1	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	1	1
ARM repeat	Nucleotide cyclase	1	1
RuvA domain 2-like	SH2 domain	1	1
PAZ domain	TPR-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	1	1
SH3-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
F-box domain	Galactose-binding domain-like	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
FYVE/PHD zinc finger	L domain-like	1	1
Mitochondrial carrier	Cysteine alpha-hairpin motif	1	1
PH domain-like	C-terminal, gelsolin-like domain of Sec23/24	1	1
cAMP-binding domain-like	FabD/lysophospholipase-like	1	1
PRP4-like	WD40 repeat-like	1	1
vWA-like	Trimeric LpxA-like enzymes	1	1
Protein kinase-like (PK-like)	Tropomyosin	1	1
Chaperone J-domain	Fibronectin type III	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
F-box domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Supernatant protein factor (SPF), C-terminal domain	PH domain-like	1	1
vWA-like	Cysteine-rich domain	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	ARM repeat	1	1
ACP-like	Ankyrin repeat	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
CCCH zinc finger	SMR domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Restriction endonuclease-like	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Zn2/Cys6 DNA-binding domain	Ubiquitin-like	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	1	1
PUA domain-like	eIF1-like	1	1
PH domain-like	BSD domain-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
MFS general substrate transporter	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
DNase I-like	GTPase activation domain, GAP	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Translation proteins	Translation proteins	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	1	1
Ubiquitin-like	Acid proteases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Acid proteases	DNA/RNA polymerases	1	1
SWIB/MDM2 domain	SWIB/MDM2 domain	1	1
Acetyl-CoA synthetase-like	Protein kinase-like (PK-like)	1	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
SH3-domain	Ricin B-like lectins	1	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	1	1
PLP-binding barrel	Alanine racemase C-terminal domain-like	1	1
Calponin-homology domain, CH-domain	GAS2 domain-like	1	1
Sec63 N-terminal domain-like	Ribonuclease H-like	1	1
Tetrapyrrole methylase	Riboflavin synthase domain-like	1	1
Chromo domain-like	SET domain	1	1
SH3-domain	GAT-like domain	1	1
Spermadhesin, CUB domain	Kelch motif	1	1
Apolipoprotein A-I	MAPEG domain-like	1	1
Second domain of FERM	alpha-catenin/vinculin-like	1	1
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
PurS-like	PurM N-terminal domain-like	1	1
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	1	1
Class II aaRS and biotin synthetases	SufE/NifU	1	1
PH domain-like	Phospholipase D/nuclease	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Rap/Ran-GAP	1	1
Methionine synthase domain	Methionine synthase activation domain-like	1	1
BRCT domain	PsbU/PolX domain-like	1	1
HR1 repeat	Ubiquitin-like	1	1
Chaperone J-domain	E set domains	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Tudor/PWWP/MBT	1	1
RNA-binding domain, RBD	WD40 repeat-like	1	1
GTPase activation domain, GAP	GTPase activation domain, GAP	1	1
Cysteine proteinases	Concanavalin A-like lectins/glucanases	1	1
"Winged helix" DNA-binding domain	DBL homology domain (DH-domain)	1	1
TolB, C-terminal domain	TPR-like	1	1
F-box domain	Ankyrin repeat	1	1
Folate-binding domain	Folate-binding domain	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	1	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	1	1
alpha-helical ferredoxin	Nucleotide-binding domain	1	1
Bromodomain	Tudor/PWWP/MBT	1	1
Clathrin heavy-chain terminal domain	ARM repeat	1	1
PurS-like	PurM C-terminal domain-like	1	1
Thioesterase/thiol ester dehydrase-isomerase	Thiolase-like	1	1
SH3-domain	GTPase activation domain, GAP	1	1
ISP domain	Ferritin-like	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
UBC-like	Ribosomal protein S5 domain 2-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
Microbial and mitochondrial ADK, insert "zinc finger" domain	EF-hand	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
L domain-like	PP2C-like	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Homeodomain-like	FAD-linked reductases, C-terminal domain	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
SAM/Pointed domain	PH domain-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SET domain	1	1
UBA-like	XPC-binding domain	1	1
Chromo domain-like	Homeodomain-like	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	1	1
TPR-like	RNI-like	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	1	1
NAD(P)-binding Rossmann-fold domains	4'-phosphopantetheinyl transferase	1	1
14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	1	1
Thiolase-like	GroES-like	1	1
Activating enzymes of the ubiquitin-like proteins	Rhodanese/Cell cycle control phosphatase	1	1
Chaperone J-domain	SAM/Pointed domain	1	1
Voltage-gated potassium channels	Voltage-gated potassium channels	1	1
Dehydroquinate synthase-like	P-loop containing nucleoside triphosphate hydrolases	1	1
TK C-terminal domain-like	Flavoproteins	1	1
Ribonuclease H-like	HRDC-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
BEACH domain	WD40 repeat-like	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
Ankyrin repeat	Protein kinase-like (PK-like)	1	1
SAM/Pointed domain	SAM/Pointed domain	1	1
GST C-terminal domain-like	PRTase-like	1	1
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	1	1
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
Fibronectin type III	RING/U-box	1	1
Ribonuclease H-like	Ran binding protein zinc finger-like	1	1
RING/U-box	R3H domain	1	1
Cysteine-rich domain	DBL homology domain (DH-domain)	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
BRCT domain	DNA/RNA polymerases	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
SAP domain	F-box domain	1	1
Subunits of heterodimeric actin filament capping protein Capz	Translin	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
CCCH zinc finger	RING/U-box	1	1
Eukaryotic type KH-domain (KH-domain type I)	SAM/Pointed domain	1	1
Barwin-like endoglucanases	LysM domain	1	1
NAD kinase/diacylglycerol kinase-like	Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	1	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, N-terminal domain	1	1
ARM repeat	"Winged helix" DNA-binding domain	1	1
WD40 repeat-like	C-terminal, gelsolin-like domain of Sec23/24	1	1
DUSP-like	Cysteine proteinases	1	1
LysM domain	Chitinase insertion domain	1	1
DBL homology domain (DH-domain)	CAD & PB1 domains	1	1
GroEL equatorial domain-like	MFS general substrate transporter	1	1
SET domain	WW domain	1	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	1	1
Calponin-homology domain, CH-domain	GTPase activation domain, GAP	1	1
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	1	1
EF-hand	PLC-like phosphodiesterases	1	1
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	1	1
Calponin-homology domain, CH-domain	PRC-barrel domain	1	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Carbohydrate-binding domain	(Trans)glycosidases	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
Protein kinase-like (PK-like)	ASF1-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	EGF/Laminin	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
WD40 repeat-like	SMAD/FHA domain	1	1
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	Riboflavin synthase domain-like	1	1
Protein kinase-like (PK-like)	WW domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	1	1
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	1	1
Translation proteins SH3-like domain	DnaJ/Hsp40 cysteine-rich domain	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
Methyl-accepting chemotaxis protein (MCP) signaling domain	CheY-like	1	1
Regulator of G-protein signaling, RGS	PH domain-like	1	1
FabD/lysophospholipase-like	ACP-like	1	1
RNA-binding domain, RBD	PWI domain	1	1
Creatinase/aminopeptidase	beta-N-acetylhexosaminidase-like domain	1	1
WD40 repeat-like	VHP, Villin headpiece domain	1	1
PFL-like glycyl radical enzymes	Hedgehog/intein (Hint) domain	1	1
Siroheme synthase middle domains-like	TK C-terminal domain-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Galactose oxidase, central domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
I/LWEQ domain	I/LWEQ domain	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	1	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	1	1
Bet v1-like	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
vWA-like	C-terminal domain of Ku80	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
SMAD/FHA domain	BRCT domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Nucleoporin domain	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
ARM repeat	Growth factor receptor domain	1	1
PIN domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
GroEL apical domain-like	MFS general substrate transporter	1	1
Periplasmic binding protein-like II	SH3-domain	1	1
UBC-like	Class II aaRS ABD-related	1	1
Spermadhesin, CUB domain	Growth factor receptor domain	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	1	1
P-loop containing nucleoside triphosphate hydrolases	Zn2/Cys6 DNA-binding domain	1	1
TPR-like	F-box domain	1	1
SNARE-like	Ankyrin repeat	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Regulator of G-protein signaling, RGS	HR1 repeat	1	1
HR1 repeat	PH domain-like	1	1
Family A G protein-coupled receptor-like	C-terminal domain of adenylylcyclase associated protein	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	P-loop containing nucleoside triphosphate hydrolases	1	1
TK C-terminal domain-like	Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	1	1
ADP-ribosylation	B-box zinc-binding domain	1	1
RNA-binding domain, RBD	SET domain	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
L domain-like	Ubiquitin-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Regulator of G-protein signaling, RGS	Ubiquitin-like	1	1
Dihydropteroate synthetase-like	Cobalamin (vitamin B12)-binding domain	1	1
PFL-like glycyl radical enzymes	PFL-like glycyl radical enzymes	1	1
EF-hand	Riboflavin synthase domain-like	1	1
Tudor/PWWP/MBT	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
WD40 repeat-like	BRCT domain	1	1
RING/U-box	PUA domain-like	1	1
Myosin rod fragments	Myosin rod fragments	1	1
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	1	1
TK C-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	1	1
Retrovirus zinc finger-like domains	HIT-like	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Zn-dependent exopeptidases	Zn-dependent exopeptidases	1	1
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
EGF/Laminin	Integrin alpha N-terminal domain	1	1
Regulator of G-protein signaling, RGS	Regulator of G-protein signaling, RGS	1	1
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	1	1
Chitinase insertion domain	Hormone receptor domain	1	1
SAP domain	Mob1/phocein	1	1
BAR/IMD domain-like	BAR/IMD domain-like	1	1
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	1	1
NAD(P)-binding Rossmann-fold domains	TK C-terminal domain-like	1	1
Quinoprotein alcohol dehydrogenase-like	Ypt/Rab-GAP domain of gyp1p	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
FYVE/PHD zinc finger	"Winged helix" DNA-binding domain	1	1
HAD-like	BRCT domain	1	1
PH domain-like	BEACH domain	1	1
GAT-like domain	Clathrin adaptor appendage domain	1	1
Clc chloride channel	Clc chloride channel	1	1
Flavoproteins	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Homocysteine S-methyltransferase	Methionine synthase activation domain-like	1	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	1	1
RING/U-box	Clavaminate synthase-like	1	1
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	Ankyrin repeat	1	1
ARM repeat	Kringle-like	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
RNA-binding domain, RBD	SPOC domain-like	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
Tudor/PWWP/MBT	S-adenosyl-L-methionine-dependent methyltransferases	1	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Heme-dependent catalase-like	FAD/NAD(P)-binding domain	1	1
Transcription factor IIA (TFIIA), beta-barrel domain	UBA-like	1	1
E set domains	Growth factor receptor domain	1	1
Heme-dependent peroxidases	SH3-domain	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
UBC-like	RING/U-box	1	1
Tetrapyrrole methylase	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Glutathione synthetase ATP-binding domain-like	Aldolase	1	1
Thiolase-like	4'-phosphopantetheinyl transferase	1	1
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
MIT domain	MIT domain	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
Family A G protein-coupled receptor-like	Galactose-binding domain-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
ArfGap/RecO-like zinc finger	UBA-like	1	1
TRAF domain-like	Cysteine proteinases	1	1
SMAD/FHA domain	Leucine zipper domain	1	1
Growth factor receptor domain	EGF/Laminin	1	1
Calponin-homology domain, CH-domain	Protein kinase-like (PK-like)	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	Cysteine proteinases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Regulator of G-protein signaling, RGS	1	1
DBL homology domain (DH-domain)	WW domain	1	1
Nucleotidylyl transferase	Nucleotidylyl transferase	1	1
Ribulose-phoshate binding barrel	Ribulose-phoshate binding barrel	1	1
ARID-like	FYVE/PHD zinc finger	1	1
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	1	1
LysM domain	LysM domain	1	1
L domain-like	NTF2-like	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
WD40 repeat-like	Leucine zipper domain	1	1
CoA-dependent acyltransferases	NAD(P)-binding Rossmann-fold domains	1	1
Rudiment single hybrid motif	Aldolase	1	1
BAR/IMD domain-like	WD40 repeat-like	1	1
LysM domain	(Trans)glycosidases	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	1	1
FAD/NAD(P)-binding domain	P-loop containing nucleoside triphosphate hydrolases	1	1
CoA-transferase family III (CaiB/BaiF)	CoA-transferase family III (CaiB/BaiF)	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	1	1
Homeodomain-like	FYVE/PHD zinc finger	1	1
alpha/beta-Hydrolases	Protein kinase-like (PK-like)	1	1
Flavoproteins	Radical SAM enzymes	1	1
Mitochondrial import receptor subunit Tom20	SET domain	1	1
NAD(P)-binding Rossmann-fold domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Cobalamin (vitamin B12)-binding domain	Methionine synthase activation domain-like	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
Thioesterase/thiol ester dehydrase-isomerase	SCP-like	1	1
Supernatant protein factor (SPF), C-terminal domain	Oxysterol-binding protein-like	1	1
PapD-like	PapD-like	1	1
TRAF domain-like	POZ domain	1	1
P-loop containing nucleoside triphosphate hydrolases	F-box domain	1	1
Ankyrin repeat	MIT domain	1	1
HIT/MYND zinc finger-like	TPR-like	1	1
NAD(P)-binding Rossmann-fold domains	Riboflavin synthase domain-like	1	1
Tetrapyrrole methylase	TK C-terminal domain-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	PX domain	1	1
Amine oxidase N-terminal region	Amine oxidase catalytic domain	1	1
SMAD/FHA domain	PapD-like	1	1
GroEL equatorial domain-like	GroEL equatorial domain-like	1	1
Regulator of G-protein signaling, RGS	DBL homology domain (DH-domain)	1	1
ENTH/VHS domain	SH3-domain	1	1
Translation proteins SH3-like domain	HSP40/DnaJ peptide-binding domain	1	1
Cysteine-rich domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Thioredoxin-like	ERP29 C domain-like	1	1
FKBP-like	FKBP-like	1	1
L9 N-domain-like	Ribosomal protein L9 C-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	HD-domain/PDEase-like	1	1
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	1	1
Retrovirus zinc finger-like domains	RING/U-box	1	1
Glycerol-3-phosphate (1)-acyltransferase	Glycerol-3-phosphate (1)-acyltransferase	1	1
Cyclophilin-like	TPR-like	1	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Aldolase	NAD(P)-binding Rossmann-fold domains	1	1
ARM repeat	PapD-like	1	1
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
WD40 repeat-like	Cyclophilin-like	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
Plant lectins/antimicrobial peptides	Glycoside hydrolase/deacetylase	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
Six-hairpin glycosidases	Six-hairpin glycosidases	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1
FabD/lysophospholipase-like	4'-phosphopantetheinyl transferase	1	1
Polo-box domain	Polo-box domain	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
Zn2/Cys6 DNA-binding domain	beta-sandwich domain of Sec23/24	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
Nudix	ARM repeat	1	1
Siroheme synthase middle domains-like	Thiamin diphosphate-binding fold (THDP-binding)	1	1
DNA-glycosylase	Nudix	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Rhomboid-like	UBA-like	1	1
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	1	1
Ribokinase-like	Heme oxygenase-like	1	1
DBL homology domain (DH-domain)	PX domain	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
GAF domain-like	ARM repeat	1	1
Protein kinase-like (PK-like)	DBL homology domain (DH-domain)	1	1
Cysteine-rich domain	GTPase activation domain, GAP	1	1
Chorismate mutase II	Periplasmic binding protein-like II	1	1
Nucleotidyltransferase	Retrovirus zinc finger-like domains	1	1
ARM repeat	4'-phosphopantetheinyl transferase	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
Periplasmic binding protein-like I	HD-domain/PDEase-like	1	1
PH domain-like	CAD & PB1 domains	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	(Phosphotyrosine protein) phosphatases II	1	1
P-loop containing nucleoside triphosphate hydrolases	GAF domain-like	1	1
Prokaryotic type I DNA topoisomerase	FMN-binding split barrel	1	1
UROD/MetE-like	UROD/MetE-like	1	1
Homeodomain-like	FAD/NAD(P)-binding domain	1	1
FYVE/PHD zinc finger	Elongation factor TFIIS domain 2	1	1
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	1	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	P-loop containing nucleoside triphosphate hydrolases	1	1
UBA-like	TPR-like	1	1
Galactose-binding domain-like	(Trans)glycosidases	1	1
Calponin-homology domain, CH-domain	RGC domain-like	1	1
FabD/lysophospholipase-like	FabD/lysophospholipase-like	1	1
R3H domain	Ribonuclease H-like	1	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	1	1
CoA-dependent acyltransferases	Protein kinase-like (PK-like)	1	1
MIT domain	Cysteine proteinases	1	1
RNI-like	WD40 repeat-like	1	1
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	1	1
PH domain-like	Ras GEF	1	1
Aldolase	Single hybrid motif	1	1
NTF2-like	UBA-like	1	1
Protein kinase-like (PK-like)	MIT domain	1	1
PH domain-like	I/LWEQ domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	ISP domain	1	1
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
MIT domain	FYVE/PHD zinc finger	1	1
Urease, gamma-subunit	Metallo-dependent hydrolases	1	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	DNA breaking-rejoining enzymes	1	1
Kelch motif	Fibronectin type III	1	1
HAMP domain-like	Homodimeric domain of signal transducing histidine kinase	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Glucocorticoid receptor-like (DNA-binding domain)	FYVE/PHD zinc finger	1	1
ARM repeat	Chromo domain-like	1	1
Galactose-binding domain-like	HSP90 C-terminal domain	1	1
t-snare proteins	ARM repeat	1	1
Arp2/3 complex subunits	Arp2/3 complex subunits	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	1	1
RmlC-like cupins	Zn-dependent exopeptidases	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Phosphofructokinase	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Cytidine deaminase-like	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
Eukaryotic type KH-domain (KH-domain type I)	WD40 repeat-like	1	1
SMAD/FHA domain	dsRNA-binding domain-like	1	1
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
WD40 repeat-like	TolB, C-terminal domain	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
PreATP-grasp domain	Aldolase	1	1
Fibronectin type III	Growth factor receptor domain	1	1
Methylglyoxal synthase-like	Metallo-dependent hydrolases	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
PX domain	GTPase activation domain, GAP	1	1
Bromodomain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
alpha/beta-Hydrolases	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
PYP-like sensor domain (PAS domain)	Nucleotide cyclase	1	1
RCC1/BLIP-II	RCC1/BLIP-II	1	1
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PAP/OAS1 substrate-binding domain	Retrovirus zinc finger-like domains	1	1
NTF2-like	RNA-binding domain, RBD	1	1
Cytochrome b5-like heme/steroid binding domain	FMN-linked oxidoreductases	1	1
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	Growth factor receptor domain	1	1
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	1	1
Methyl-accepting chemotaxis protein (MCP) signaling domain	Homodimeric domain of signal transducing histidine kinase	1	1
DnaJ/Hsp40 cysteine-rich domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Multidrug resistance efflux transporter EmrE	1	1
SET domain	MFS general substrate transporter	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
NAD(P)-binding Rossmann-fold domains	Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	1	1
Phosphofructokinase	Phosphofructokinase	1	1
EPT/RTPC-like	Aldolase	1	1
FMN-linked oxidoreductases	Nucleotide-binding domain	1	1
Carbohydrate binding domain	(Trans)glycosidases	1	1
PH domain-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	ARM repeat	1	1
TPR-like	Metallo-hydrolase/oxidoreductase	1	1
PreATP-grasp domain	PurM C-terminal domain-like	1	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
BRCT domain	Nucleotidyltransferase	1	1
Siroheme synthase middle domains-like	Riboflavin synthase domain-like	1	1
Amine oxidase N-terminal region	Amine oxidase N-terminal region	1	1
ARM repeat	Peptidase/esterase 'gauge' domain	1	1
Cytochrome b5-like heme/steroid binding domain	SMAD/FHA domain	1	1
Tropomyosin	PH domain-like	1	1
Nucleic acid-binding proteins	HIT-like	1	1
DBL homology domain (DH-domain)	FYVE/PHD zinc finger	1	1
PAZ domain	FKBP-like	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
UBA-like	Hect, E3 ligase catalytic domain	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
SET domain	Bromodomain	1	1
Siroheme synthase middle domains-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
WD40 repeat-like	DNase I-like	1	1
Zn-dependent exopeptidases	RNA-binding domain, RBD	1	1
Ubiquitin-like	HAD-like	1	1
Growth factor receptor domain	Kringle-like	1	1
SH3-domain	Ankyrin repeat	1	1
Pseudouridine synthase	PUA domain-like	1	1
Acid proteases	UBA-like	1	1
Tex N-terminal region-like	SH2 domain	1	1
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	1	1
Ubiquitin-like	DBL homology domain (DH-domain)	1	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	1	1
Cysteine proteinases	Ribonuclease H-like	1	1
Dehydroquinate synthase-like	Aldolase	1	1
RNI-like	PP2C-like	1	1
EF-hand	FAD-linked oxidoreductase	1	1
FAD/NAD(P)-binding domain	Acyl-CoA N-acyltransferases (Nat)	1	1
GAF domain-like	HD-domain/PDEase-like	1	1
ARM repeat	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Thioredoxin-like	Nucleoside diphosphate kinase, NDK	1	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	1	1
SMAD/FHA domain	PH domain-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Growth factor receptor domain	1	1
SMAD/FHA domain	Macro domain-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
HAD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
EF-hand	DBL homology domain (DH-domain)	1	1
ARM repeat	RING/U-box	1	1
PH domain-like	VHP, Villin headpiece domain	1	1
GroEL-intermediate domain like	SAICAR synthase-like	1	1
Plant lectins/antimicrobial peptides	Hormone receptor domain	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
Osmotin, thaumatin-like protein	Chitinase insertion domain	1	1
HSP20-like chaperones	HCP-like	1	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PLP-dependent transferases	1	1
Ubiquitin-like	RNI-like	1	1
PH domain-like	TPR-like	1	1
Cytochrome b5-like heme/steroid binding domain	Arginase/deacetylase	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
alpha/beta-Hydrolases	post-AAA+ oligomerization domain-like	1	1
TGS-like	Class II aaRS ABD-related	1	1
UBC-like	UBA-like	1	1
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	1	1
Spectrin repeat	EF-hand	1	1
WW domain	Hect, E3 ligase catalytic domain	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Thioesterase/thiol ester dehydrase-isomerase	4'-phosphopantetheinyl transferase	1	1
Somatomedin B domain	Fibronectin type III	1	1
SAM/Pointed domain	RING/U-box	1	1
Homeodomain-like	ARM repeat	1	1
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Galactose oxidase, central domain	SH3-domain	1	1
EPT/RTPC-like	Aminoacid dehydrogenase-like, N-terminal domain	1	1
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-binding domain	1	1
Periplasmic binding protein-like II	Growth factor receptor domain	1	1
EF-hand	UBA-like	1	1
UBA-like	SMR domain-like	1	1
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
UBA-like	Chaperone J-domain	1	1
DNA topoisomerase IV, alpha subunit	DNA topoisomerase IV, alpha subunit	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
Methyl-accepting chemotaxis protein (MCP) signaling domain	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
DNA-binding domain of Mlu1-box binding protein MBP1	Glucocorticoid receptor-like (DNA-binding domain)	1	1
HMG-box	HMG-box	1	1
SET domain	Tudor/PWWP/MBT	1	1
PH domain-like	A middle domain of Talin 1	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Class II aaRS and biotin synthetases	Translation proteins	1	1
PIN domain-like	beta-beta-alpha zinc fingers	1	1
P-loop containing nucleoside triphosphate hydrolases	PAH2 domain	1	1
Creatinase/aminopeptidase	(Trans)glycosidases	1	1
PreATP-grasp domain	post-HMGL domain-like	1	1
Frizzled cysteine-rich domain	Family A G protein-coupled receptor-like	1	1
Galactose oxidase, central domain	Ribosomal protein S5 domain 2-like	1	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	1	1
Chromo domain-like	RING/U-box	1	1
Tetrapyrrole methylase	Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	1	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	1	1
Translation proteins SH3-like domain	Chaperone J-domain	1	1
RNA-binding domain, RBD	ARM repeat	1	1
Tetrapyrrole methylase	Thiamin diphosphate-binding fold (THDP-binding)	1	1
post-HMGL domain-like	Single hybrid motif	1	1
RNA-binding domain, RBD	Ran binding protein zinc finger-like	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
Acetyl-CoA synthetase-like	Ankyrin repeat	1	1
HR1 repeat	ARM repeat	1	1
TATA-box binding protein-like	TATA-box binding protein-like	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
RNI-like	Nucleotide cyclase	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
PH domain-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
GTPase activation domain, GAP	ARM repeat	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
Concanavalin A-like lectins/glucanases	BEACH domain	1	1
Homocysteine S-methyltransferase	Methionine synthase domain	1	1
RING/U-box	FYVE/PHD zinc finger	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
TPR-like	RNA-binding domain, RBD	1	1
TPR-like	Phosphoenolpyruvate/pyruvate domain	1	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	1	1
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	1	1
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, catalytic domain	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
Kelch motif	POZ domain	1	1
WWE domain	RING/U-box	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Integrin alpha N-terminal domain	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	1	1
PreATP-grasp domain	PurM N-terminal domain-like	1	1
F-box domain	YccV-like	1	1
ACP-like	Protein kinase-like (PK-like)	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	1	1
Inosine monophosphate dehydrogenase (IMPDH)	4'-phosphopantetheinyl transferase	1	1
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	1	1
NAD(P)-binding Rossmann-fold domains	Thiamin diphosphate-binding fold (THDP-binding)	1	1
Indigoidine synthase A-like	Ribokinase-like	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
PP2C-like	Nucleotide cyclase	1	1
TPR-like	MM3350-like	1	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Tropomyosin	Cysteine-rich domain	1	1
L domain-like	DNase I-like	1	1
Myosin S1 fragment, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
TRAF domain-like	TPR-like	1	1
L domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Spectrin repeat	Spectrin repeat	1	1
Quinoprotein alcohol dehydrogenase-like	ARM repeat	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	UBA-like	1	1
Tudor/PWWP/MBT	Chromo domain-like	1	1
Macro domain-like	RNA-binding domain, RBD	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	1	1
Second domain of FERM	Second domain of FERM	1	1
Galactose-binding domain-like	Galactose oxidase, central domain	1	1
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Thioesterase/thiol ester dehydrase-isomerase	NAD(P)-binding Rossmann-fold domains	1	1
ARM repeat	Zn-dependent exopeptidases	1	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
BRCT domain	ARM repeat	1	1
Subtilisin-like	C-type lectin-like	1	1
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	1	1
Calponin-homology domain, CH-domain	WW domain	1	1
PH domain-like	FYVE/PHD zinc finger	1	1
RNI-like	L domain-like	1	1
Surp module (SWAP domain)	Retrovirus zinc finger-like domains	1	1
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
Cytochrome b5-like heme/steroid binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
CCCH zinc finger	Retrovirus zinc finger-like domains	1	1
Transcription factor IIA (TFIIA), beta-barrel domain	RING/U-box	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
Carbamate kinase-like	PUA domain-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Transcription factor IIA (TFIIA), beta-barrel domain	Cysteine proteinases	1	1
ENTH/VHS domain	I/LWEQ domain	1	1
PH domain-like	Cullin repeat-like	1	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	1	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
POZ domain	NAD(P)-binding Rossmann-fold domains	1	1
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	1	1
beta-sandwich domain of Sec23/24	Nucleotide-diphospho-sugar transferases	1	1
ARM repeat	UBA-like	1	1
alpha/beta-Hydrolases	BRCT domain	1	1
Metallo-dependent phosphatases	Growth factor receptor domain	1	1
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Kringle-like	EGF/Laminin	1	1
Ubiquitin-like	A middle domain of Talin 1	1	1
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	1	1
RNI-like	Putative isomerase YbhE	1	1
PAH2 domain	PAH2 domain	1	1
Somatomedin B domain	Nucleotide-diphospho-sugar transferases	1	1
RING/U-box	UBA-like	1	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	1	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
Homocysteine S-methyltransferase	Cobalamin (vitamin B12)-binding domain	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
SH3-domain	RING/U-box	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
SH3-domain	Ras GEF	1	1
SAM/Pointed domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Fibronectin type III	BRCT domain	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
SAP domain	RNA-binding domain, RBD	1	1
Quinoprotein alcohol dehydrogenase-like	Cyclophilin-like	1	1
DNA-binding protein LAG-1 (CSL)	E set domains	1	1
TK C-terminal domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Ubiquitin-like	ADP-ribosylation	1	1
Chaperone J-domain	CSL zinc finger	1	1
Fibronectin type III	EGF/Laminin	1	1
Family A G protein-coupled receptor-like	Subtilisin-like	1	1
Cytochrome P450	Flavoproteins	1	1
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	1	1
WD40 repeat-like	Ribonuclease H-like	1	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	1	1
L domain-like	Chromo domain-like	1	1
ARM repeat	Fibronectin type III	1	1
Translation proteins	ThrRS/AlaRS common domain	1	1
Ribonuclease H-like	Hedgehog/intein (Hint) domain	1	1
Taf5 N-terminal domain-like	WD40 repeat-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Nitrite/Sulfite reductase N-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	1	1
Rabenosyn-5 Rab-binding domain-like	L domain-like	1	1
RING/U-box	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Osmotin, thaumatin-like protein	Plant lectins/antimicrobial peptides	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	1	1
Plant lectins/antimicrobial peptides	Chitinase insertion domain	1	1
HR1 repeat	DBL homology domain (DH-domain)	1	1
SMAD/FHA domain	Nucleotide cyclase	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Ankyrin repeat	Oxysterol-binding protein-like	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
FYVE/PHD zinc finger	GroEL-intermediate domain like	1	1
Heme-dependent catalase-like	ACP-like	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
DPP6 N-terminal domain-like	TPR-like	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
TPR-like	CAD & PB1 domains	1	1
WD40 repeat-like	Bromodomain	1	1
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	1	1
A middle domain of Talin 1	I/LWEQ domain	1	1
Cysteine proteinases	UBA-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Kringle-like	1	1
Ankyrin repeat	CCCH zinc finger	1	1
Tropomyosin	Tropomyosin	1	1
TK C-terminal domain-like	Riboflavin synthase domain-like	1	1
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	1	1
RING/U-box	RNA-binding domain, RBD	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
P-loop containing nucleoside triphosphate hydrolases	Aldolase	1	1
ADP-ribosylation	Nucleotide-diphospho-sugar transferases	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
NAD(P)-binding Rossmann-fold domains	Nucleotidylyl transferase	1	1
Galactose-binding domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	1	1
HAD-like	HAD-like	1	1
Ribulose-phoshate binding barrel	Tryptophan synthase beta subunit-like PLP-dependent enzymes	1	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	1	1
Chaperone J-domain	RING/U-box	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
CAD & PB1 domains	UBA-like	1	1
C-terminal domain of RNA polymerase alpha subunit	P-loop containing nucleoside triphosphate hydrolases	1	1
Class I glutamine amidotransferase-like	PreATP-grasp domain	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	1	1
SMAD/FHA domain	GAF domain-like	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
PP2C-like	WD40 repeat-like	1	1
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	1	1
t-snare proteins	Histone-fold	1	1
Cytochrome P450	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Enolase N-terminal domain-like	Enolase C-terminal domain-like	1	1
Kelch motif	Growth factor receptor domain	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
RING/U-box	EF-hand	1	1
FabD/lysophospholipase-like	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Heme oxygenase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
dsRNA-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	TPR-like	1	1
Nitrite/Sulfite reductase N-terminal domain-like	ISP domain	1	1
SET domain	SET domain	1	1
Class I glutamine amidotransferase-like	Class II aaRS and biotin synthetases	1	1
L domain-like	E set domains	1	1
RING/U-box	Cyclophilin-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Multiheme cytochromes	1	1
Fibronectin type III	Kringle-like	1	1
Ankyrin repeat	POZ domain	1	1
FYVE/PHD zinc finger	Rabenosyn-5 Rab-binding domain-like	1	1
SAM/Pointed domain	Ubiquitin-like	1	1
ARM repeat	EGF/Laminin	1	1
BRCT domain	Leucine zipper domain	1	1
POZ domain	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	1	1
Metalloproteases ("zincins"), catalytic domain	Mannose-binding lectins	1	1
Thioredoxin-like	ARM repeat	1	1
Histone-fold	ARM repeat	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
E set domains	AMPKBI-like	1	1
CCCH zinc finger	CHY zinc finger-like	1	1
NAD(P)-binding Rossmann-fold domains	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Rudiment single hybrid motif	PurM C-terminal domain-like	1	1
Protein kinase-like (PK-like)	Polo-box domain	1	1
DNA-binding protein LAG-1 (CSL)	DNA-binding protein LAG-1 (CSL)	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	1	1
EPT/RTPC-like	P-loop containing nucleoside triphosphate hydrolases	1	1
S-adenosylmethionine decarboxylase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Riboflavin synthase domain-like	1	1
PH domain-like	alpha-catenin/vinculin-like	1	1
Calponin-homology domain, CH-domain	Spectrin repeat	1	1
Osmotin, thaumatin-like protein	Hormone receptor domain	1	1
Chaperone J-domain	RNA-binding domain, RBD	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
DBL homology domain (DH-domain)	BAR/IMD domain-like	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
WW domain	Ras GEF	1	1
FAD/NAD(P)-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
WD40 repeat-like	Soluble quinoprotein glucose dehydrogenase	1	1
Thiamin phosphate synthase	Ribokinase-like	1	1
UBC-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Plant lectins/antimicrobial peptides	(Trans)glycosidases	1	1
L domain-like	UBA-like	1	1
P-loop containing nucleoside triphosphate hydrolases	TPR-like	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
CRAL/TRIO domain	GTPase activation domain, GAP	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Fibronectin type III	SAM/Pointed domain	1	1
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	1	1
Ribonuclease H-like	CCCH zinc finger	1	1
Composite domain of metallo-dependent hydrolases	YrdC/RibB	1	1
HIT/MYND zinc finger-like	Creatinase/aminopeptidase	1	1
WD40 repeat-like	Actin depolymerizing proteins	1	1
Fibronectin type III	Ankyrin repeat	1	1
PUA domain-like	Nucleotidylyl transferase	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
L domain-like	Growth factor receptor domain	1	1
Nudix	CCCH zinc finger	1	1
YjgF-like	YjgF-like	1	1
vWA-like	SAP domain	1	1
WW domain	FKBP-like	1	1
CCCH zinc finger	ARM repeat	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Microbial and mitochondrial ADK, insert "zinc finger" domain	1	1
SH3-domain	CAD & PB1 domains	1	1
Ribonuclease H-like	SH2 domain	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	1	1
E set domains	Ankyrin repeat	1	1
EF-hand	WD40 repeat-like	1	1
ClpS-like	"Winged helix" DNA-binding domain	1	1
Dehydroquinate synthase-like	EPT/RTPC-like	1	1
ACT-like	Formyltransferase	1	1
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	1	1
WD40 repeat-like	Cysteine proteinases	1	1
(Trans)glycosidases	Fibronectin type III	1	1
TPR-like	PYP-like sensor domain (PAS domain)	1	1
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
(Trans)glycosidases	Six-hairpin glycosidases	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
Thiolase-like	ACP-like	1	1
C-terminal, gelsolin-like domain of Sec23/24	Actin depolymerizing proteins	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
HAMP domain-like	CheY-like	1	1
Ankyrin repeat	Tropomyosin	1	1
Ribosomal protein L19 (L19e)	Ribosomal protein L19 (L19e)	1	1
Protein kinase-like (PK-like)	HD-domain/PDEase-like	1	1
Macro domain-like	HIT-like	1	1
alpha/beta-Hydrolases	(Phosphotyrosine protein) phosphatases II	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
TRAF domain-like	Tropomyosin	1	1
Thioredoxin-like	SAP domain	1	1
Cysteine-rich domain	Ubiquitin-like	1	1
Rudiment single hybrid motif	post-HMGL domain-like	1	1
Carbohydrate binding domain	beta-sandwich domain of Sec23/24	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
"Winged helix" DNA-binding domain	CheY-like	1	1
ISP domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
FAD-linked reductases, C-terminal domain	EF-hand	1	1
GroES-like	ACP-like	1	1
Ubiquitin-like	Protein kinase-like (PK-like)	1	1
I/LWEQ domain	alpha-catenin/vinculin-like	1	1
EPT/RTPC-like	NAD(P)-binding Rossmann-fold domains	1	1
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	1	1
Ankyrin repeat	Ras GEF	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
SPOC domain-like	SAP domain	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
PLP-dependent transferases	NAD(P)-binding Rossmann-fold domains	1	1
Rhodanese/Cell cycle control phosphatase	Cysteine proteinases	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	Hedgehog/intein (Hint) domain	1	1
RNase III domain-like	dsRNA-binding domain-like	1	1
TPR-like	HD-domain/PDEase-like	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
(Trans)glycosidases	Hormone receptor domain	1	1
Apolipoprotein A-I	Apolipoprotein A-I	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
Fibronectin type III	Nucleotide-diphospho-sugar transferases	1	1
Protein kinase-like (PK-like)	WD40 repeat-like	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
Seven-hairpin glycosidases	PA domain	1	1
PreATP-grasp domain	Metallo-dependent hydrolases	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
Chorismate mutase II	ACT-like	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
F-box domain	Concanavalin A-like lectins/glucanases	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	RING/U-box	1	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	1	1
Cap-Gly domain	L domain-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Fibronectin type III	1	1
Aldolase	post-HMGL domain-like	1	1
GroEL apical domain-like	SAICAR synthase-like	1	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
Bromodomain	Ankyrin repeat	1	1
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	1	1
UBC-like	UBC-like	1	1
PLP-dependent transferases	PLP-dependent transferases	1	1
beta-sandwich domain of Sec23/24	PX domain	1	1
Flavoproteins	Nitrite/Sulfite reductase N-terminal domain-like	1	1
FAD/NAD(P)-binding domain	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
cAMP-binding domain-like	FAD/NAD(P)-binding domain	1	1
Rudiment single hybrid motif	PurM N-terminal domain-like	1	1
Protein kinase-like (PK-like)	CheY-like	1	1
Ubiquitin-like	XPC-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	1	1
FabD/lysophospholipase-like	GroES-like	1	1
Spermadhesin, CUB domain	E set domains	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
Nucleic acid-binding proteins	HSP40/DnaJ peptide-binding domain	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
ARM repeat	BEACH domain	1	1
Nucleotide-diphospho-sugar transferases	Diaminopimelate epimerase-like	1	1
FabD/lysophospholipase-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
Homocysteine S-methyltransferase	Dihydropteroate synthetase-like	1	1
The spindle assembly checkpoint protein mad2	FYVE/PHD zinc finger	1	1
Siroheme synthase middle domains-like	Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	1	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	1	1
Dehydroquinate synthase-like	NAD(P)-binding Rossmann-fold domains	1	1
Regulator of G-protein signaling, RGS	Cysteine-rich domain	1	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	1	1
Tudor/PWWP/MBT	RING/U-box	1	1