With NAD(+) or NADP(+) as acceptor

---

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children)	EC term [EC ID] <#Children>	(#SF|#FA)	#Supra-domain (Single|Duplex|Triple)
+ + + 3:	root [root] <6>
+ + 2:	Oxidoreductases [1] <23>	(183|263)	(202|169|83)
+ 1:	Acting on the CH-NH(2) group of donors [1.4] <9>	(19|22)	(20|12|3)
0:	With NAD(+) or NADP(+) as acceptor [1.4.1] <21>	(9|9)	(10|4|0)
- 1:	2,4-diaminopentanoate dehydrogenase [1.4.1.12]	(0|0)	(0|0|0)
- 1:	Alanine dehydrogenase [1.4.1.1]	(1|2)	(1|1|0)
- 1:	Aspartate dehydrogenase [1.4.1.21]	(1|1)	(1|1|0)
- 1:	Diaminopimelate dehydrogenase [1.4.1.16]	(0|0)	(0|0|0)
- 1:	Glutamate dehydrogenase [1.4.1.2]	(0|0)	(0|0|0)
- 1:	Glutamate dehydrogenase (NAD(P)(+)) [1.4.1.3]	(1|2)	(1|1|0)
- 1:	Glutamate dehydrogenase (NADP(+)) [1.4.1.4]	(1|2)	(1|1|0)
- 1:	Glutamate synthase (NADH) [1.4.1.14]	(4|3)	(5|0|0)
- 1:	Glutamate synthase (NADPH) [1.4.1.13]	(3|1)	(5|1|0)
- 1:	Glycine dehydrogenase [1.4.1.10]	(0|0)	(0|0|0)
- 1:	L-amino-acid dehydrogenase [1.4.1.5]	(0|0)	(0|0|0)
- 1:	L-erythro-3,5-diaminohexanoate dehydrogenase [1.4.1.11]	(0|0)	(0|0|0)
- 1:	Leucine dehydrogenase [1.4.1.9]	(0|0)	(0|0|0)
- 1:	Lysine 6-dehydrogenase [1.4.1.18]	(0|0)	(0|0|0)
- 1:	Lysine dehydrogenase [1.4.1.15]	(0|0)	(0|0|0)
- 1:	N-methylalanine dehydrogenase [1.4.1.17]	(0|0)	(0|0|0)
- 1:	Phenylalanine dehydrogenase [1.4.1.20]	(0|0)	(0|0|0)
- 1:	Serine 2-dehydrogenase [1.4.1.7]	(0|0)	(0|0|0)
- 1:	Transferred entry: 1.21.4.1 [1.4.1.6]	(0|0)	(0|0|0)
- 1:	Tryptophan dehydrogenase [1.4.1.19]	(0|0)	(0|0|0)
- 1:	Valine dehydrogenase (NADP(+)) [1.4.1.8]	(0|0)	(0|0|0)

---

Superfamily

Superfamily domains annotated to this EC term (SDEO level: Informative)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Aminoacid dehydrogenase-like, N-terminal domain	0	DIRECT
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	0	DIRECT
alpha-helical ferredoxin	0	DIRECT
Formate/glycerate dehydrogenase catalytic domain-like	0	DIRECT
NAD(P)-binding Rossmann-fold domains	0	DIRECT
FMN-linked oxidoreductases	0.00008571	DIRECT
Alpha subunit of glutamate synthase, C-terminal domain	0.0003024	DIRECT
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.0004956	DIRECT
Nucleotide-binding domain	0.09521	INHERITED FROM: Glutamate synthase (NADPH)

---

Family

Family domains annotated to this (SDEO level: Highly Informative)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
L-alanine dehydrogenase-like	0	DIRECT
Dihydrodipicolinate reductase-like	0	DIRECT
Aminoacid dehydrogenases	0	DIRECT
Aminoacid dehydrogenase-like, C-terminal domain	0	DIRECT
Formate/glycerate dehydrogenases, NAD-domain	0	DIRECT
N-terminal domain of adrenodoxin reductase-like	0.00000000000002845	DIRECT
FMN-linked oxidoreductases	0.0001025	DIRECT
Alpha subunit of glutamate synthase, C-terminal domain	0.0003508	DIRECT
Class II glutamine amidotransferases	0.0005749	DIRECT

---

Supra-domain (including individual superfamily)

Supra-domains annotated to this EC term (SPEO level: Highly Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
NAD(P)-binding Rossmann-fold domains	0	DIRECT
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	0	DIRECT
alpha-helical ferredoxin	0	DIRECT
Formate/glycerate dehydrogenase catalytic domain-like	0	DIRECT
Aminoacid dehydrogenase-like, N-terminal domain	0	DIRECT
FMN-linked oxidoreductases	0.00007607	DIRECT
Alpha subunit of glutamate synthase, C-terminal domain	0.0002695	DIRECT
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.0004434	DIRECT
Nucleotide-binding domain	0.08811	INHERITED FROM: Glutamate synthase (NADPH)
FAD/NAD(P)-binding domain	1	INHERITED FROM: Glutamate synthase (NADH)

Supra-domains annotated to this EC term (SPEO level: Highly Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
46548,51971 46548 - alpha-helical ferredoxin 51971 - Nucleotide-binding domain	0	DIRECT
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains	0	DIRECT
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains	0	DIRECT
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	0	DIRECT