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Transferases
(show info)
Enzyme Commission (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed. To navigate hierarchical structure of EC, we display all parental EC terms to the current EC term of interest ordered by their shortest distances to the current term. Also, only direct children EC terms of the current EC term are listed.
Structural Classification of Proteins (SCOP)
SCOP classifies evolutionary-related domains into Superfamily level and Family level. Accordingly, we have generated the domain-centric EC annotations for each of the three concepts at each of the two domain levels.
Structural Domain Enzyme Commission Ontology (SDEO)
As domain-centric ontology, SDEO only refers to those EC terms which are the most informative to annotate SCOP domains.
EC annotations for SCOP domains
For details, please visit Documentation: EC annotations for SCOP domains. Therein, we provide several relevant files ( Data Availability) for the download, including an annotation file (i.e., Domain2EC.txt) and the corresponding ontology (i.e., SDEO.txt).
Supra-domain Enzyme Commission Ontology (SPEO)
As an extension, SPEO includes those EC terms which are the most informative to annotate supra-domains and individual SCOP domains at the Superfamily level.
EC annotations for Supra-domains
For details, please visit Documentation: EC annotations for Supra-domains. Therein, we provide several relevant files ( Data Availability) for the download, including a annotation file (i.e., SP2EC.txt) and an ontology (i.e., SPEO.txt). For the sake of being browsable, listed below are those supra-domains (single, dual, triple, quad).
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (Not in SDEO)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| E set domains | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
| Cobalamin adenosyltransferase-like | 0 | DIRECT |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Riboflavin kinase-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| RPB5-like RNA polymerase subunit | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| Methionine synthase domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Malate synthase G | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| NadA-like | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Thiamin phosphate synthase | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
| MoeA N-terminal region -like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| DmpA/ArgJ-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| PHP14-like | 0 | DIRECT |
| Phosphohistidine domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| ThiG-like | 0 | DIRECT |
| PHP domain-like | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
| Tetrapyrrole methylase | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| MoeA C-terminal domain-like | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| DAK1/DegV-like | 0 | DIRECT |
| Methionine synthase activation domain-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| PilZ domain-like | 0 | DIRECT |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| PTS system IIB component-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| GlnB-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Penicillin binding protein dimerisation domain | 0 | DIRECT |
| tRNA-guanine transglycosylase | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| RNA polymerase subunits | 0 | DIRECT |
| RPB6/omega subunit-like | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| HAMP domain-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| AF1104-like | 0 | DIRECT |
| Methyl-coenzyme M reductase subunits | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| PLP-dependent transferases | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| SufE/NifU | 0 | DIRECT |
| Poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Siroheme synthase middle domains-like | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| TTHA0583/YokD-like | 0 | DIRECT |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| NusB-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Molybdopterin synthase subunit MoaE | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Pyridoxine 5'-phosphate synthase | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| PsbU/PolX domain-like | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Aspartate/ornithine carbamoyltransferase | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Lumazine synthase | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| PK C-terminal domain-like | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 9.368e-16 | DIRECT |
| Sensory domain-like | 0.00000000000004716 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0.00000000000005118 | DIRECT |
| Fibronectin type III | 0.0000000000002029 | DIRECT |
| Fic-like | 0.0000000000003506 | DIRECT |
| L30e-like | 0.000000000003861 | DIRECT |
| PIN domain-like | 0.000000000004546 | DIRECT |
| ARM repeat | 0.000000000005204 | DIRECT |
| Phospholipase D/nuclease | 0.0000000003056 | DIRECT |
| Bromodomain | 0.0000000007605 | DIRECT |
| Ricin B-like lectins | 0.000000001157 | DIRECT |
| HprK N-terminal domain-like | 0.000000007721 | DIRECT |
| Chromo domain-like | 0.00000001143 | DIRECT |
| beta-beta-alpha zinc fingers | 0.00000002098 | DIRECT |
| Terpenoid synthases | 0.00000002248 | DIRECT |
| Duplicated hybrid motif | 0.00000003482 | DIRECT |
| Glycosyl hydrolase domain | 0.00000003843 | DIRECT |
| Single hybrid motif | 0.00000004218 | DIRECT |
| RNI-like | 0.0000000454 | DIRECT |
| Ankyrin repeat | 0.0000004976 | DIRECT |
| FYVE/PHD zinc finger | 0.0000007927 | DIRECT |
| CoA-transferase family III (CaiB/BaiF) | 0.000001295 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0.00004172 | DIRECT |
| GckA/TtuD-like | 0.0001737 | DIRECT |
| Homeodomain-like | 0.000432 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0.0007171 | DIRECT |
| Second domain of FERM | 0.001035 | INHERITED FROM: Protein-tyrosine kinases || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase |
| HMG-box | 0.001198 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001198 | INHERITED FROM: Glutamate formimidoyltransferase || Transferring one-carbon groups || Hydroxymethyl-, formyl- and related transferases |
| SMAD/FHA domain | 0.001887 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.002451 | INHERITED FROM: Phosphatidylinositol-4,5-bisphosphate 3-kinase || Phosphatidylinositol-4-phosphate 3-kinase || Protein-serine/threonine kinases || Phosphatidylinositol 3-kinase || Transferring phosphorous-containing groups || Protein kinase C |
| Tudor/PWWP/MBT | 0.004339 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || DNA (cytosine-5-)-methyltransferase || Histone-lysine N-methyltransferase |
| Coronavirus NSP8-like | 0.004598 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Coronavirus NSP7-like | 0.004598 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Replicase NSP9 | 0.004598 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Coronavirus NSP10-like | 0.004598 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| YWTD domain | 0.006311 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases || Transferring phosphorous-containing groups |
| PX domain | 0.006345 | INHERITED FROM: Non-specific serine/threonine protein kinase || Phosphatidylinositol-4-phosphate 3-kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| MIT domain | 0.01166 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Ubiquitin-like | 0.01422 | INHERITED FROM: Phosphatidylinositol-4,5-bisphosphate 3-kinase || Phosphatidylinositol-4-phosphate 3-kinase || Protein-serine/threonine kinases || Protein-tyrosine kinases || Phosphatidylinositol 3-kinase || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase || Phosphotransferases with an alcohol group as accep |
| C-type lectin-like | 0.01507 | INHERITED FROM: Transferring phosphorous-containing groups |
| CRAL/TRIO domain | 0.01895 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| GAF domain-like | 0.02165 | INHERITED FROM: Transferring phosphorous-containing groups || Protein-histidine kinases |
| WW domain | 0.02277 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| RNA-binding domain, RBD | 0.02572 | INHERITED FROM: Polynucleotide adenylyltransferase || tRNA (carboxymethyluridine(34)-5-O)-methyltransfer || RNA uridylyltransferase || Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| NSP3A-like | 0.0386 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| SCP-like | 0.04247 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Propanoyl-CoA C-acyltransferase |
| Acid proteases | 0.05234 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| Hedgehog/intein (Hint) domain | 0.06771 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| MAPEG domain-like | 0.08074 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than meth |
| WD40 repeat-like | 0.109 | INHERITED FROM: Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Homing endonucleases | 0.137 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| Quinoprotein alcohol dehydrogenase-like | 0.1541 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| DEATH domain | 0.1693 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Cell wall binding repeat | 0.1921 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
| P-loop containing nucleoside triphosphate hydrolases | 0.2181 | INHERITED FROM: Phosphoribulokinase || tRNA(Met) cytidine acetyltransferase || Sulfotransferases || Thymidine kinase || Nicotinate riboside kinase || Guanylate kinase || RNA-directed RNA polymerase || Phosphotransferases with a phosphate group as acce || Tetraacyldisaccharide 4'-kinase || Adenylate kinase || Polynucleotide 5'-hydroxyl-kinase || Transferring alkyl or aryl groups, other than meth || Shikimate kinase || dTMP kinase || Dephospho-CoA kinase || 6-phosphofructo-2-kinase || Ribosylnicotinamide kinase || mRNA (guanine-N(7)-)-methyltransferase || Phosphate acetyltransferase || Sulfate adenylyltransferase || Adenylyl-sulfate kinase || (d)CMP kinase || mRNA (nucleoside-2'-O-)-methyltransferase || Transferring phosphorous-containing groups || tRNA dimethylallyltransferase || Phosphotransferases with an alcohol group as accep || Uridine kinase |
| EF-hand | 0.238 | INHERITED FROM: Transaldolase || Non-specific serine/threonine protein kinase || Diacylglycerol kinase || Protein-serine/threonine kinases || Calcium/calmodulin-dependent protein kinase || 1-alkylglycerophosphocholine O-acetyltransferase || Transferring phosphorous-containing groups || 1-acylglycerophosphocholine O-acyltransferase |
| Cobalamin (vitamin B12)-binding domain | 0.4147 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Methionine synthase |
| FabD/lysophospholipase-like | 0.4349 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || Fatty-acyl-CoA synthase || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| HIT-like | 0.4892 | INHERITED FROM: UDP-glucose--hexose-1-phosphate uridylyltransferas || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| TPR-like | 0.5089 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein O-GlcNAc transferase || Histone-lysine N-methyltransferase || Adenosine monophosphate-protein transferase |
| Trypsin-like serine proteases | 0.5287 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || mRNA (guanine-N(7)-)-methyltransferase || mRNA (nucleoside-2'-O-)-methyltransferase || Transferring phosphorous-containing groups |
| Rubredoxin-like | 0.5692 | INHERITED FROM: Phosphotransferases with a phosphate group as acce || Adenylate kinase |
| Starch-binding domain-like | 0.579 | INHERITED FROM: Glycosyltransferases || Hexosyltransferases || Cyclomaltodextrin glucanotransferase |
| CYTH-like phosphatases | 0.6825 | INHERITED FROM: mRNA guanylyltransferase |
| NTF2-like | 0.7167 | INHERITED FROM: Protein-serine/threonine kinases || Calcium/calmodulin-dependent protein kinase || Transferring phosphorous-containing groups |
| RING/U-box | 0.8302 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Glycosyltransferases || Hexosyltransferases || Histone acetyltransferase || Cellulose synthase (UDP-forming) |
| UROD/MetE-like | 0.8335 | INHERITED FROM: 5-methyltetrahydropteroyltriglutamate--homocystein || Transferring one-carbon groups || Methyltransferases |
| Thioredoxin-like | 0.8861 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than meth || Protein-histidine kinases |
| Dihydropteroate synthetase-like | 1 | INHERITED FROM: Tetrahydromethanopterin S-methyltransferase || Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine || Methyltransferases || Transferring alkyl or aryl groups, other than meth || Methionine synthase || Dihydropteroate synthase |
| Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| Globin-like | 1 | INHERITED FROM: Diguanylate cyclase |
| cAMP-binding domain-like | 1 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
| (Trans)glycosidases | 1 | INHERITED FROM: 4-alpha-glucanotransferase || 1,4-alpha-glucan branching enzyme || Dextransucrase || Galactinol--sucrose galactosyltransferase || Glycosyltransferases || Hexosyltransferases || Starch synthase (maltosyl-transferring) || Cyclomaltodextrin glucanotransferase |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: Thymidine kinase || NAD(+) ADP-ribosyltransferase || Transferring phosphorous-containing groups || Phosphotransferases with an alcohol group as accep |
| PurM N-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
| Heme oxygenase-like | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphomethylpyrimidine kinase |
| Kringle-like | 1 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| Zinc beta-ribbon | 1 | INHERITED FROM: Nucleotidyltransferases || DNA-directed RNA polymerase |
| Translation proteins | 1 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase |
| Macro domain-like | 1 | INHERITED FROM: RNA-directed RNA polymerase || NAD(+) ADP-ribosyltransferase || Nucleotidyltransferases |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| CheY-like | 1 | INHERITED FROM: Transferring phosphorous-containing groups || Protein-histidine kinases |
| Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl on transfer |
| PFL-like glycyl radical enzymes | 1 | INHERITED FROM: Formate C-acetyltransferase || Acyltransferases || Transferring groups other than amino-acyl groups |
| Ribonuclease H-like | 1 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| Galactose-binding domain-like | 1 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Homoserine O-succinyltransferase || Acyltransferases || Transferring groups other than amino-acyl groups || Aminodeoxychorismate synthase |
| SAICAR synthase-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Inositol-trisphosphate 3-kinase || 1-phosphatidylinositol-3-phosphate 5-kinase || 1-phosphatidylinositol-5-phosphate 4-kinase || Inositol-polyphosphate multikinase || 1-phosphatidylinositol-4-phosphate 5-kinase || Phosphotransferases with an alcohol group as accep |
| IpsF-like | 1 | INHERITED FROM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltrans || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Inositol-1,3,4-trisphosphate 5/6-kinase || Inositol-hexakisphosphate kinase || ATP citrate synthase || Pyruvate, phosphate dikinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Pyruvate, water dikinase || Inositol-tetrakisphosphate 1-kinase || Diphosphoinositol-pentakisphosphate kinase |
| Glycoside hydrolase/deacetylase | 1 | INHERITED FROM: Transferring other glycosyl groups |
| Phosphoglycerate mutase-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || 6-phosphofructo-2-kinase || Diphosphoinositol-pentakisphosphate kinase |
| beta-lactamase/transpeptidase-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Hexosyltransferases |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: Caffeate O-methyltransferase || Acetylserotonin O-methyltransferase || CTP-dependent riboflavin kinase || Histone acetyltransferase |
| Families 57/38 glycoside transferase middle domain | 1 | INHERITED FROM: Hexosyltransferases |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| ACP-like | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| Acetyl-CoA synthetase-like | 1 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Acyl-[acyl-carrier-protein]--phospholipid O-acyltr |
| RmlC-like cupins | 1 | INHERITED FROM: Mannose-1-phosphate guanylyltransferase |
| HAD-like | 1 | INHERITED FROM: Polynucleotide 5'-hydroxyl-kinase || Alpha,alpha-trehalose-phosphate synthase (UDP-form || N-acylneuraminate cytidylyltransferase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Transferases for other substituted phosphate group || Phosphatidylglycerol--membrane-oligosaccharide gly |
| GroES-like | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| NagB/RpiA/CoA transferase-like | 1 | INHERITED FROM: CoA-transferases || Transferring sulfur-containing groups |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: Cysteate synthase || Transferring alkyl or aryl groups, other than meth || Cysteine synthase |
| Six-hairpin glycosidases | 1 | INHERITED FROM: 4-alpha-glucanotransferase |
| Cysteine proteinases | 1 | INHERITED FROM: Arylamine N-acetyltransferase || Protein-glutamine gamma-glutamyltransferase || Acyltransferases || Glutathione gamma-glutamylcysteinyltransferase || Aminoacyltransferases |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | INHERITED FROM: tRNA (guanine(37)-N(1))-methyltransferase |
| BRCT domain | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || DNA nucleotidylexotransferase |
| PurM C-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | INHERITED FROM: Amidophosphoribosyltransferase || Glutamine--fructose-6-phosphate transaminase (isom || Transferring nitrogenous groups || Gamma-glutamyltransferase || Aminoacyltransferases || Transaminases (aminotransferases) |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase |
| HD-domain/PDEase-like | 1 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase || [Protein-PII] uridylyltransferase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Class II aaRS and biotin synthetases | 1 | INHERITED FROM: Lipoate--protein ligase || Acyltransferases || Transferring groups other than amino-acyl groups || Lipoyl(octanoyl) transferase || Lysyltransferase |
| Clavaminate synthase-like | 1 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransfer || RNA-directed RNA polymerase |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Phosphatidylcholine--sterol O-acyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase || Malonyl-CoA O-methyltransferase || Homoserine O-acetyltransferase |
| Lysozyme-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase |
| PDZ domain-like | 1 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| Ribonuclease Rh-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| FAD-linked oxidases, C-terminal domain | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase || Transferring alkyl or aryl groups, other than meth |
| ADC-like | 1 | INHERITED FROM: Thymidine phosphorylase |
| Nucleotide cyclase | 1 | INHERITED FROM: Diguanylate cyclase |
| post-HMGL domain-like | 1 | INHERITED FROM: 2-isopropylmalate synthase || Acyltransferases || Acyl groups converted into alkyl on transfer |
| SIS domain | 1 | INHERITED FROM: Glutamine--fructose-6-phosphate transaminase (isom || Transferring nitrogenous groups || Glucokinase || Transaminases (aminotransferases) |
| UBA-like | 1 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| TGS-like | 1 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase |
| Adenine nucleotide alpha hydrolases-like | 1 | INHERITED FROM: Sulfurtransferases || Nucleotidyltransferases || FAD synthetase || Transferring sulfur-containing groups || Sulfate adenylyltransferase || tRNA sulfurtransferase |
| Zn-dependent exopeptidases | 1 | INHERITED FROM: Glutaminyl-peptide cyclotransferase || Aminoacyltransferases |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: Polyribonucleotide nucleotidyltransferase || mRNA guanylyltransferase || Nucleotidyltransferases || Lysyltransferase || 23S rRNA (uracil(1939)-C(5))-methyltransferase |
| Nucleotidylyl transferase | 1 | INHERITED FROM: UMP/CMP kinase || Ethanolamine-phosphate cytidylyltransferase || Nicotinamide-nucleotide adenylyltransferase || Pantetheine-phosphate adenylyltransferase || Nicotinate-nucleotide adenylyltransferase || Nucleotidyltransferases || FAD synthetase || Riboflavin kinase || Choline-phosphate cytidylyltransferase || Sulfate adenylyltransferase || Transferring phosphorous-containing groups |
| Dehydroquinate synthase-like | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than meth || Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || Phosphotransferases with an alcohol group as accep |
| tRNA-binding arm | 1 | INHERITED FROM: glycyltransferase |
| dUTPase-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: ATP citrate synthase || Aspartate kinase || Uroporphyrinogen-III C-methyltransferase || UDP-4-amino-4-deoxy-L-arabinose formyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Shikimate kinase || Fatty-acid synthase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| FAD/NAD(P)-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Transferring one-carbon groups || Methyltransferases || (FADH(2)-oxidizing) |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| Glutamine synthetase/guanido kinase | 1 | INHERITED FROM: Phosphotransferases with a nitrogenous group as ac || Creatine kinase |
| Terpenoid cyclases/Protein prenyltransferases | 1 | INHERITED FROM: Protein geranylgeranyltransferase type I || Protein geranylgeranyltransferase type II || Protein farnesyltransferase || Transferring alkyl or aryl groups, other than meth |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Thymidylate synthase |
| Riboflavin synthase domain-like | 1 | INHERITED FROM: Riboflavin synthase |
| Arabinanase/levansucrase/invertase | 1 | INHERITED FROM: Hexosyltransferases || Levansucrase |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase |
| Nucleotide-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Methyltransferases |
| Pentein | 1 | INHERITED FROM: Amidinotransferases |
| FAD-binding/transporter-associated domain-like | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase |
| FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Methyltransferases |
| FMN-linked oxidoreductases | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than meth || Phosphoglycerol geranylgeranyltransferase |
| ADC synthase | 1 | INHERITED FROM: Transferring nitrogenous groups || Aminodeoxychorismate synthase || Transaminases (aminotransferases) |
| Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: Xyloglucan:xyloglucosyl transferase || Glycosyltransferases || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Hexosyltransferases |
| PreATP-grasp domain | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
| SH3-domain | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
| HPr-like | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| E set domains | 0 | Direct |
| PH domain-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
| Cobalamin adenosyltransferase-like | 0 | Direct |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| AF1531-like | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| CheW-like | 0 | Direct |
| Riboflavin kinase-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| RPB5-like RNA polymerase subunit | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| Methionine synthase domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Malate synthase G | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
| Aldolase | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| NadA-like | 0 | Direct |
| CofD-like | 0 | Direct |
| Sema domain | 0 | Direct |
| Thiamin phosphate synthase | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
| MoeA N-terminal region -like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| DNA clamp | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| SH2 domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| DmpA/ArgJ-like | 0 | Direct |
| KA1-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| PHP14-like | 0 | Direct |
| Phosphohistidine domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| EndoU-like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| ThiG-like | 0 | Direct |
| PHP domain-like | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
| Tetrapyrrole methylase | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| MoeA C-terminal domain-like | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| DAK1/DegV-like | 0 | Direct |
| Methionine synthase activation domain-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Putative methyltransferase TM0872, insert domain | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Histone-fold | 0 | Direct |
| PilZ domain-like | 0 | Direct |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| PTS system IIB component-like | 0 | Direct |
| MIR domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| GlnB-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Penicillin binding protein dimerisation domain | 0 | Direct |
| tRNA-guanine transglycosylase | 0 | Direct |
| TAZ domain | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| DhaL-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| RNA polymerase subunits | 0 | Direct |
| RPB6/omega subunit-like | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| PRTase-like | 0 | Direct |
| HAMP domain-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| ACT-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Plexin repeat | 0 | Direct |
| AF1104-like | 0 | Direct |
| Methyl-coenzyme M reductase subunits | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| SET domain | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| PLP-dependent transferases | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| SufE/NifU | 0 | Direct |
| Poly(A) polymerase catalytic subunit-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Siroheme synthase middle domains-like | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| TTHA0583/YokD-like | 0 | Direct |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| NusB-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| L domain-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Molybdopterin synthase subunit MoaE | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Pyridoxine 5'-phosphate synthase | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| HR1 repeat | 0 | Direct |
| PsbU/PolX domain-like | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Aspartate/ornithine carbamoyltransferase | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Lumazine synthase | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| PK C-terminal domain-like | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 9.368e-16 | Direct |
| Sensory domain-like | 0.00000000000004716 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0.00000000000005118 | Direct |
| Fibronectin type III | 0.0000000000002029 | Direct |
| Fic-like | 0.0000000000003506 | Direct |
| L30e-like | 0.000000000003861 | Direct |
| PIN domain-like | 0.000000000004546 | Direct |
| ARM repeat | 0.000000000005204 | Direct |
| Phospholipase D/nuclease | 0.0000000003056 | Direct |
| Bromodomain | 0.0000000007605 | Direct |
| Ricin B-like lectins | 0.000000001157 | Direct |
| HprK N-terminal domain-like | 0.000000007721 | Direct |
| Chromo domain-like | 0.00000001143 | Direct |
| beta-beta-alpha zinc fingers | 0.00000002098 | Direct |
| Terpenoid synthases | 0.00000002248 | Direct |
| Duplicated hybrid motif | 0.00000003482 | Direct |
| Glycosyl hydrolase domain | 0.00000003843 | Direct |
| Single hybrid motif | 0.00000004218 | Direct |
| RNI-like | 0.0000000454 | Direct |
| Ankyrin repeat | 0.0000004976 | Direct |
| FYVE/PHD zinc finger | 0.0000007927 | Direct |
| CoA-transferase family III (CaiB/BaiF) | 0.000001295 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0.00004172 | Direct |
| GckA/TtuD-like | 0.0001737 | Direct |
| Homeodomain-like | 0.000432 | Direct |
| beta-sandwich domain of Sec23/24 | 0.0007171 | Direct |
| Second domain of FERM | 0.001035 | Inherited |
| HMG-box | 0.001198 | Inherited |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001198 | Inherited |
| SMAD/FHA domain | 0.001887 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.002451 | Inherited |
| Tudor/PWWP/MBT | 0.004339 | Inherited |
| Coronavirus NSP8-like | 0.004598 | Inherited |
| Coronavirus NSP7-like | 0.004598 | Inherited |
| Replicase NSP9 | 0.004598 | Inherited |
| Coronavirus NSP10-like | 0.004598 | Inherited |
| YWTD domain | 0.006311 | Inherited |
| PX domain | 0.006345 | Inherited |
| MIT domain | 0.01166 | Inherited |
| Ubiquitin-like | 0.01422 | Inherited |
| C-type lectin-like | 0.01507 | Inherited |
| CRAL/TRIO domain | 0.01895 | Inherited |
| GAF domain-like | 0.02165 | Inherited |
| WW domain | 0.02277 | Inherited |
| RNA-binding domain, RBD | 0.02572 | Inherited |
| NSP3A-like | 0.0386 | Inherited |
| SCP-like | 0.04247 | Inherited |
| Acid proteases | 0.05234 | Inherited |
| Hedgehog/intein (Hint) domain | 0.06771 | Inherited |
| MAPEG domain-like | 0.08074 | Inherited |
| WD40 repeat-like | 0.109 | Inherited |
| Homing endonucleases | 0.137 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1541 | Inherited |
| DEATH domain | 0.1693 | Inherited |
| Cell wall binding repeat | 0.1921 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.2181 | Inherited |
| EF-hand | 0.238 | Inherited |
| Cobalamin (vitamin B12)-binding domain | 0.4147 | Inherited |
| FabD/lysophospholipase-like | 0.4349 | Inherited |
| HIT-like | 0.4892 | Inherited |
| TPR-like | 0.5089 | Inherited |
| Trypsin-like serine proteases | 0.5287 | Inherited |
| Rubredoxin-like | 0.5692 | Inherited |
| Starch-binding domain-like | 0.579 | Inherited |
| CYTH-like phosphatases | 0.6825 | Inherited |
| NTF2-like | 0.7167 | Inherited |
| RING/U-box | 0.8302 | Inherited |
| UROD/MetE-like | 0.8335 | Inherited |
| Thioredoxin-like | 0.8861 | Inherited |
| Dihydropteroate synthetase-like | 1 | Inherited |
| Rudiment single hybrid motif | 1 | Inherited |
| Globin-like | 1 | Inherited |
| cAMP-binding domain-like | 1 | Inherited |
| (Trans)glycosidases | 1 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
| PurM N-terminal domain-like | 1 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| Kringle-like | 1 | Inherited |
| Zinc beta-ribbon | 1 | Inherited |
| Translation proteins | 1 | Inherited |
| Macro domain-like | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| CheY-like | 1 | Inherited |
| Succinyl-CoA synthetase domains | 1 | Inherited |
| PFL-like glycyl radical enzymes | 1 | Inherited |
| Ribonuclease H-like | 1 | Inherited |
| Galactose-binding domain-like | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Class I glutamine amidotransferase-like | 1 | Inherited |
| SAICAR synthase-like | 1 | Inherited |
| IpsF-like | 1 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
| Glycoside hydrolase/deacetylase | 1 | Inherited |
| Phosphoglycerate mutase-like | 1 | Inherited |
| beta-lactamase/transpeptidase-like | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| Families 57/38 glycoside transferase middle domain | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| ACP-like | 1 | Inherited |
| Acetyl-CoA synthetase-like | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| HAD-like | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| GroES-like | 1 | Inherited |
| NagB/RpiA/CoA transferase-like | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| Six-hairpin glycosidases | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | Inherited |
| BRCT domain | 1 | Inherited |
| PurM C-terminal domain-like | 1 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | Inherited |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| HD-domain/PDEase-like | 1 | Inherited |
| Class II aaRS and biotin synthetases | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| Lysozyme-like | 1 | Inherited |
| PDZ domain-like | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
| FAD-linked oxidases, C-terminal domain | 1 | Inherited |
| ADC-like | 1 | Inherited |
| Nucleotide cyclase | 1 | Inherited |
| post-HMGL domain-like | 1 | Inherited |
| SIS domain | 1 | Inherited |
| UBA-like | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Adenine nucleotide alpha hydrolases-like | 1 | Inherited |
| Zn-dependent exopeptidases | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Dehydroquinate synthase-like | 1 | Inherited |
| tRNA-binding arm | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| FAD/NAD(P)-binding domain | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| Glutamine synthetase/guanido kinase | 1 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| Riboflavin synthase domain-like | 1 | Inherited |
| Arabinanase/levansucrase/invertase | 1 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | Inherited |
| Nucleotide-binding domain | 1 | Inherited |
| Pentein | 1 | Inherited |
| FAD-binding/transporter-associated domain-like | 1 | Inherited |
| FAD-linked reductases, C-terminal domain | 1 | Inherited |
| FMN-linked oxidoreductases | 1 | Inherited |
| ADC synthase | 1 | Inherited |
| Concanavalin A-like lectins/glucanases | 1 | Inherited |
| PreATP-grasp domain | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this (Not in SDEO)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| Class I DAHP synthetase | 0 | DIRECT |
| N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Nsp15 C-terminal domain-like | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Squalene synthase | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| PPK middle domain-like | 0 | DIRECT |
| Siroheme synthase middle domains-like | 0 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| Class-II DAHP synthetase | 0 | DIRECT |
| Pyruvate kinase | 0 | DIRECT |
| CoaX-like | 0 | DIRECT |
| Molybdenum cofactor biosynthesis protein MoeB | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Malate synthase G | 0 | DIRECT |
| AF1104-like | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Methyltetrahydrofolate-utiluzing methyltransferases | 0 | DIRECT |
| Enolpyruvate transferase, EPT | 0 | DIRECT |
| Motor proteins | 0 | DIRECT |
| RBP11/RpoL | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| mRNA cap (Guanine N-7) methyltransferase | 0 | DIRECT |
| N-acetyl-l-glutamate kinase | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Pyruvate oxidase and decarboxylase PP module | 0 | DIRECT |
| ADP-specific Phosphofructokinase/Glucokinase | 0 | DIRECT |
| FucT-like | 0 | DIRECT |
| Thiamin biosynthesis kinases | 0 | DIRECT |
| TRAM domain | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Thiopurine S-methyltransferase | 0 | DIRECT |
| Legume lectins | 0 | DIRECT |
| Molybdopterin synthase subunit MoaE | 0 | DIRECT |
| Holo-(acyl carrier protein) synthase ACPS | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Receiver domain of the ethylene receptor | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| RIO1-like kinases | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| Methyl-coenzyme M reductase gamma chain | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Trehalose-6-phosphate synthase, OtsA | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Leucine carboxy methyltransferase Ppm1 | 0 | DIRECT |
| O-acetyltransferase | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| THUMP domain | 0 | DIRECT |
| Aspartate/ornithine carbamoyltransferase | 0 | DIRECT |
| Retrovirus capsid protein C-terminal domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Inosicase | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Glucose-inhibited division protein B (GidB) | 0 | DIRECT |
| Peptidoglycan biosynthesis glycosyltransferase MurG | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| Phytochelatin synthase | 0 | DIRECT |
| Arylamine N-methyltransferase | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| IlvH-like | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| Thiamin phosphate synthase | 0 | DIRECT |
| MoeA N-terminal region -like | 0 | DIRECT |
| Salicylic acid carboxyl methyltransferase (SAMT) | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Aspartokinase allosteric domain-like | 0 | DIRECT |
| Viral proteases | 0 | DIRECT |
| MarR-like transcriptional regulators | 0 | DIRECT |
| Exostosin | 0 | DIRECT |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | DIRECT |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
| RNA helicase | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| APH phosphotransferases | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Pyridoxine 5'-phosphate synthase | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
| SP1160 C-terminal domain-like | 0 | DIRECT |
| MoeA central domain-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| RPB6 | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| NadC C-terminal domain-like | 0 | DIRECT |
| Plant O-methyltransferase, N-terminal domain | 0 | DIRECT |
| TK-like PP module | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
| N6 adenine-specific DNA methylase, DAM | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| CTP-dependent riboflavin kinase-like | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Chemotaxis protein CheA P1 domain | 0 | DIRECT |
| Tpt1/KptA | 0 | DIRECT |
| UbiE/COQ5-like | 0 | DIRECT |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
| Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
| MraW-like putative methyltransferases | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| ATP sulfurylase C-terminal domain | 0 | DIRECT |
| RhoA-binding domain | 0 | DIRECT |
| PTS system, Lactose/Cellobiose specific IIB subunit | 0 | DIRECT |
| glucose-1-phosphate thymidylyltransferase | 0 | DIRECT |
| Chalcone synthase-like | 0 | DIRECT |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| DsbA-like | 0 | DIRECT |
| double-SIS domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme substrate-binding domain | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Deoxyhypusine synthase, DHS | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Phytochrome-specific domain | 0 | DIRECT |
| LFTR-like | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Methionine synthase SAM-binding domain | 0 | DIRECT |
| Immunodeficiency virus matrix proteins | 0 | DIRECT |
| RmsB N-terminal domain-like | 0 | DIRECT |
| Glutaminyl-peptide cyclotransferase-like | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| YggJ N-terminal domain-like | 0 | DIRECT |
| mannose-1-phosphate guanylyl transferase | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| TK-like Pyr module | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Galactoside acetyltransferase-like | 0 | DIRECT |
| HAMP domain | 0 | DIRECT |
| Pyruvate phosphate dikinase, C-terminal domain | 0 | DIRECT |
| Nsp15 N-terminal domain-like | 0 | DIRECT |
| Poly A polymerase head domain-like | 0 | DIRECT |
| Pyruvate oxidase and decarboxylase Pyr module | 0 | DIRECT |
| PyrH-like | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| N-acetyl transferase, NAT | 0 | DIRECT |
| AD-003 protein-like | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
| Sensory domain of two-component sensor kinase | 0 | DIRECT |
| Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| PlsX-like | 0 | DIRECT |
| Methionine synthase domain | 0 | DIRECT |
| RpiR-like | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Galactokinase | 0 | DIRECT |
| Cobalamin-independent methionine synthase | 0 | DIRECT |
| NadC N-terminal domain-like | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Pyruvate phosphate dikinase, central domain | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| DAK1 | 0 | DIRECT |
| RNA-dependent RNA-polymerase | 0 | DIRECT |
| TRM1-like | 0 | DIRECT |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
| N-acetylglucosaminyltransferase I | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Monomeric nicotinate phosphoribosyltransferase C-terminal domain | 0 | DIRECT |
| RPB5 | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| HTLV-II matrix protein | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| DNA polymerase III, beta subunit | 0 | DIRECT |
| Glucose permease-like | 0 | DIRECT |
| Swapped Polo-box domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| E-set domains of sugar-utilizing enzymes | 0 | DIRECT |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| LuxQ-periplasmic domain-like | 0 | DIRECT |
| Amidinotransferase | 0 | DIRECT |
| Type II thymidine kinase | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Met-10+ protein-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Ecto-ART | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Gtf glycosyltransferase | 0 | DIRECT |
| Mevalonate kinase | 0 | DIRECT |
| ThiI-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| Autoinducer synthetase | 0 | DIRECT |
| NadA-like | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| ThiG-like | 0 | DIRECT |
| Hypothetical protein MJ0882 | 0 | DIRECT |
| Spermidine synthase | 0 | DIRECT |
| Hypothetical RNA methyltransferase domain (HRMD) | 0 | DIRECT |
| tRNA(1-methyladenosine) methyltransferase-like | 0 | DIRECT |
| Glutamine synthase adenylyltransferase GlnE, domain 2 | 0 | DIRECT |
| Calmodulin-like | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| Biotin synthase | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| SRA domain-like | 0 | DIRECT |
| Glucokinase | 0 | DIRECT |
| Mycolic acid cyclopropane synthase | 0 | DIRECT |
| Flavin-binding PAS domain | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme catalytic domain | 0 | DIRECT |
| Siroheme synthase N-terminal domain-like | 0 | DIRECT |
| Single-domain sulfurtransferase | 0 | DIRECT |
| Shikimate kinase (AroK) | 0 | DIRECT |
| Type II DNA methylase | 0 | DIRECT |
| Histamine methyltransferase | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| V set domains (antibody variable domain-like) | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| PfkB-like kinase | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| YbeA-like | 0 | DIRECT |
| Homoserine kinase | 0 | DIRECT |
| Serine acetyltransferase | 0 | DIRECT |
| Gluconate kinase | 0 | DIRECT |
| Arylamine N-acetyltransferase | 0 | DIRECT |
| NAD kinase-like | 0 | DIRECT |
| MogA-like | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| DRTGG domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| UDPGT-like | 0 | DIRECT |
| Plant O-methyltransferase, C-terminal domain | 0 | DIRECT |
| ArgJ-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | DIRECT |
| LplA-like | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| N-myristoyl transferase, NMT | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| hypothetical RNA methyltransferase | 0 | DIRECT |
| mRNA capping enzyme | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| Retroviral protease (retropepsin) | 0 | DIRECT |
| Polygalacturonase inhibiting protein PGIP | 0 | DIRECT |
| YggJ C-terminal domain-like | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| MM2497-like | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Tetrapyrrole methylase | 0 | DIRECT |
| Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain N-terminal domain | 0 | DIRECT |
| PWWP domain | 0 | DIRECT |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
| I set domains | 0 | DIRECT |
| Lumazine synthase | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| Reverse transcriptase | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Ssp2 C-terminal domain-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| GlmU C-terminal domain-like | 0 | DIRECT |
| GlnE-like domain | 0 | DIRECT |
| Pyruvate phosphate dikinase, N-terminal domain | 0 | DIRECT |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
| HTS-like | 0 | DIRECT |
| Transketolase C-terminal domain-like | 0 | DIRECT |
| DNA polymerase beta-like, second domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| rRNA adenine dimethylase-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Caliciviridae-like VP | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| Guanidinoacetate methyltransferase | 0 | DIRECT |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | DIRECT |
| L domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| RNA 2'-O ribose methyltransferase substrate binding domain | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| KaiB-like | 0 | DIRECT |
| ATP-dependent riboflavin kinase-like | 0 | DIRECT |
| Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like | 0 | DIRECT |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| MoeA C-terminal domain-like | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| CoA transferase beta subunit-like | 0 | DIRECT |
| N-6 DNA Methylase-like | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| Pyruvate kinase beta-barrel domain | 0 | DIRECT |
| LIM domain | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Acetokinase-like | 0 | DIRECT |
| Methicillin resistance protein FemA probable tRNA-binding arm | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Post formyltransferase domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Aminomethyltransferase folate-binding domain | 0 | DIRECT |
| alpha-1,3-galactosyltransferase-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| ATP sulfurylase catalytic domain | 0 | DIRECT |
| ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Polyphosphate kinase C-terminal domain | 0 | DIRECT |
| N5-glutamine methyltransferase, HemK | 0 | DIRECT |
| Poxvirus poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| tRNA-guanine transglycosylase | 0 | DIRECT |
| Pyruvate kinase, C-terminal domain | 0 | DIRECT |
| T7 RNA polymerase | 0 | DIRECT |
| Cobalamin adenosyltransferase | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| phosphatase domain of polynucleotide kinase | 0 | DIRECT |
| FemXAB nonribosomal peptidyltransferases | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Histidine kinase | 0 | DIRECT |
| tRNA(m1G37)-methyltransferase TrmD | 0 | DIRECT |
| Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
| Diacylglycerol kinase-like | 0 | DIRECT |
| Penicillin binding protein dimerisation domain | 0 | DIRECT |
| RNA polymerase alpha subunit dimerisation domain | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme | 0 | DIRECT |
| Riboflavin synthase | 0 | DIRECT |
| Retroviral integrase, catalytic domain | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Type II thymidine kinase zinc finger | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Glycine N-methyltransferase | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| PBP transglycosylase domain-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| SepSecS-like | 0 | DIRECT |
| IIA domain of mannitol-specific and ntr phosphotransferase EII | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Viral cysteine protease of trypsin fold | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
| AF0751-like | 0 | DIRECT |
| Adenosine-5'phosphosulfate kinase (APS kinase) | 0 | DIRECT |
| Hexose-1-phosphate uridylyltransferase | 0 | DIRECT |
| TrmB-like | 0 | DIRECT |
| Methyltransferase 10 domain | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| RNA polymerase omega subunit | 0 | DIRECT |
| mRNA cap methylase | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| Aminoglycoside 3-N-acetyltransferase-like | 0 | DIRECT |
| ATP sulfurylase N-terminal domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| Cytidylytransferase | 0 | DIRECT |
| Multidomain sulfurtransferase (rhodanese) | 0 | DIRECT |
| Carbamate kinase | 0 | DIRECT |
| PTS system, Fructose specific IIB subunit-like | 0 | DIRECT |
| UDP N-acetylglucosamine acyltransferase | 0 | DIRECT |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
| Transglutaminase N-terminal domain | 0 | DIRECT |
| BphP N-terminal domain-like | 0 | DIRECT |
| AstA-like | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Ketopantoate hydroxymethyltransferase PanB | 0 | DIRECT |
| Oligosaccharide phosphorylase | 0 | DIRECT |
| (Uracil-5-)-methyltransferase | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE | 0 | DIRECT |
| ROK | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, C-terminal domain | 0 | DIRECT |
| Phosphotransacetylase | 3.476e-16 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 5.205e-16 | DIRECT |
| Growth factor receptor domain | 0.000000000000001553 | DIRECT |
| Fibronectin type III | 0.000000000000003089 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0.000000000000007343 | DIRECT |
| PAPS reductase-like | 0.00000000000003951 | DIRECT |
| Synaptotagmin-like (S variant) | 0.00000000000006328 | DIRECT |
| Macro domain | 0.00000000000016 | DIRECT |
| Fic-like | 0.0000000000001812 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0.0000000000006981 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.000000000003428 | DIRECT |
| Ras-binding domain, RBD | 0.000000000004648 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0.000000000009506 | DIRECT |
| PHD domain | 0.00000000001655 | DIRECT |
| Dihydropteroate synthetase | 0.00000000002673 | DIRECT |
| Bromodomain | 0.0000000001391 | DIRECT |
| Ricin B-like | 0.0000000012 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0.00000000235 | DIRECT |
| Glycosyl hydrolases family 16 | 0.000000002699 | DIRECT |
| PHP domain | 0.00000003155 | DIRECT |
| RING finger domain, C3HC4 | 0.000000216 | DIRECT |
| Ankyrin repeat | 0.0000002778 | DIRECT |
| CoA-transferase family III (CaiB/BaiF) | 0.0000004187 | DIRECT |
| ADP-ribosylating toxins | 0.0000004582 | DIRECT |
| CoA transferase alpha subunit-like | 0.0000005178 | DIRECT |
| GGDEF domain | 0.0000006263 | DIRECT |
| MoCo biosynthesis proteins | 0.000003755 | DIRECT |
| Heme-binding PAS domain | 0.000003755 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0.000008303 | DIRECT |
| RelA/SpoT domain | 0.000009973 | DIRECT |
| Levansucrase | 0.00001071 | DIRECT |
| Class II viral fusion proteins C-terminal domain | 0.00001452 | DIRECT |
| PARP-type zinc finger | 0.00003237 | DIRECT |
| AlkB-like | 0.00006078 | DIRECT |
| GckA/TtuD-like | 0.00008576 | DIRECT |
| PFL-like | 0.00009152 | DIRECT |
| Ngr ectodomain-like | 0.0001686 | DIRECT |
| FHA domain | 0.0004105 | DIRECT |
| Transglutaminase core | 0.000485 | DIRECT |
| HMG-box | 0.0007131 | DIRECT |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.0007131 | DIRECT |
| PX domain | 0.0007616 | DIRECT |
| Second domain of FERM | 0.0007751 | DIRECT |
| MIT domain | 0.00118 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Coronavirus NSP8-like | 0.001669 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Replicase NSP9 | 0.001669 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Coronavirus NSP7-like | 0.001669 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Coronavirus NSP10-like | 0.001669 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Chromo domain | 0.007019 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || DNA (cytosine-5-)-methyltransferase || Histone-lysine N-methyltransferase || Histone acetyltransferase |
| Starch-binding domain | 0.007491 | INHERITED FROM: Glycosyltransferases || Hexosyltransferases || Cyclomaltodextrin glucanotransferase |
| BadF/BadG/BcrA/BcrD-like | 0.009842 | INHERITED FROM: N-acetylglucosamine kinase || Transferring phosphorous-containing groups || Phosphotransferases with an alcohol group as accep |
| WW domain | 0.01137 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| NSP3A-like | 0.0194 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Sterol carrier protein, SCP | 0.028 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Propanoyl-CoA C-acyltransferase |
| Pyruvate oxidase and decarboxylase, middle domain | 0.04103 | INHERITED FROM: Acetolactate synthase || Transferring aldehyde or ketone residues |
| MAPEG domain | 0.04947 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than meth |
| HD domain | 0.05663 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase || Transferring phosphorous-containing groups |
| WD40-repeat | 0.0629 | INHERITED FROM: Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.08016 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as accep |
| Probable phosphatase YrbI | 0.09038 | INHERITED FROM: Nucleotidyltransferases || Transferring phosphorous-containing groups || N-acylneuraminate cytidylyltransferase |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.1381 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| Cell wall binding repeat | 0.1381 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
| First domain of FERM | 0.147 | INHERITED FROM: Protein-tyrosine kinases || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase |
| GAF domain | 0.1508 | INHERITED FROM: Transferring phosphorous-containing groups || Protein-histidine kinases |
| Canonical RBD | 0.191 | INHERITED FROM: Polynucleotide adenylyltransferase || tRNA (carboxymethyluridine(34)-5-O)-methyltransfer || RNA uridylyltransferase || Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| Third domain of FERM | 0.2521 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
| TENA/THI-4 | 0.2621 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphotransferases with a phosphate group as acce || Phosphomethylpyrimidine kinase || Phosphotransferases with an alcohol group as accep |
| Cobalamin (vitamin B12)-binding domain | 0.2824 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Methionine synthase |
| Intein (protein splicing domain) | 0.3489 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase |
| Homoserine dehydrogenase-like | 0.5352 | INHERITED FROM: Aspartate kinase || Phosphotransferases with a carboxyl group as accep |
| MaoC-like | 0.6225 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase |
| PDZ domain | 0.6225 | INHERITED FROM: Protein-serine/threonine kinases |
| Quinoprotein alcohol dehydrogenase-like | 0.6286 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| PLC-like (P variant) | 0.8668 | INHERITED FROM: Phosphatidylinositol-4,5-bisphosphate 3-kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups || Protein kinase C |
| DmpG/LeuA communication domain-like | 0.9531 | INHERITED FROM: 2-isopropylmalate synthase || Acyltransferases || Acyl groups converted into alkyl on transfer |
| cAMP-binding domain | 0.9653 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
| DHN aldolase/epimerase | 0.9865 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine |
| Ribonuclease H | 1 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase |
| Tyrosine-dependent oxidoreductases | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || UDP-4-amino-4-deoxy-L-arabinose formyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase || Hydroxymethyl-, formyl- and related transferases |
| beta-Lactamase/D-ala carboxypeptidase | 1 | INHERITED FROM: Glycosyltransferases || Peptidoglycan glycosyltransferase || Hexosyltransferases |
| Crotonase-like | 1 | INHERITED FROM: Histone acetyltransferase |
| G proteins | 1 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase |
| CoA-binding domain | 1 | INHERITED FROM: ATP citrate synthase || Acyltransferases || Acyl groups converted into alkyl on transfer |
| PurM C-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
| DNA ligase | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase |
| BC N-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase || Aspartate carbamoyltransferase |
| Anticodon-binding domain | 1 | INHERITED FROM: Lysyltransferase || Aminoacyltransferases |
| dUTPase-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| Decarboxylase | 1 | INHERITED FROM: Orotate phosphoribosyltransferase |
| IpsF-like | 1 | INHERITED FROM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltrans || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| ADC synthase | 1 | INHERITED FROM: Transferring nitrogenous groups || Aminodeoxychorismate synthase || Transaminases (aminotransferases) |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 1 | INHERITED FROM: ATP citrate synthase |
| Tetratricopeptide repeat (TPR) | 1 | INHERITED FROM: Hexosyltransferases || Protein O-GlcNAc transferase |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 1 | INHERITED FROM: Lysyltransferase |
| PurM N-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
| Elongation factors | 1 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase || Transferring phosphorous-containing groups |
| BC ATP-binding domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase || Aspartate carbamoyltransferase |
| Class I glutamine amidotransferases (GAT) | 1 | INHERITED FROM: Aminodeoxychorismate synthase |
| Extended AAA-ATPase domain | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| Dehydroquinate synthase, DHQS | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than meth || Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || Phosphotransferases with an alcohol group as accep |
| EF-hand modules in multidomain proteins | 1 | INHERITED FROM: Diacylglycerol kinase || Phosphotransferases with an alcohol group as accep |
| Dihydrofolate reductases | 1 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Thymidylate synthase |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| Acetyl-CoA synthetase-like | 1 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Acyl-[acyl-carrier-protein]--phospholipid O-acyltr |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: Cysteate synthase || Transferring alkyl or aryl groups, other than meth || Cysteine synthase |
| mono-SIS domain | 1 | INHERITED FROM: Glucokinase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| CheY-related | 1 | INHERITED FROM: Protein-histidine kinases |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 1 | INHERITED FROM: UMP/CMP kinase || Phosphotransferases with a phosphate group as acce |
| FMN-linked oxidoreductases | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than meth || Phosphoglycerol geranylgeranyltransferase |
| Kringle modules | 1 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Shikimate dehydrogenase-like | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than meth || Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || Phosphotransferases with an alcohol group as accep |
| Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl on transfer |
| Class I aldolase | 1 | INHERITED FROM: Transaldolase || Shikimate kinase || Transferring aldehyde or ketone residues || 3-phosphoshikimate 1-carboxyvinyltransferase |
| Nitrogenase iron protein-like | 1 | INHERITED FROM: Non-specific protein-tyrosine kinase |
| BC C-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| Ribonuclease Rh-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| Class I DAHP synthetase | 0 | Direct |
| N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Nsp15 C-terminal domain-like | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Squalene synthase | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| PPK middle domain-like | 0 | Direct |
| Siroheme synthase middle domains-like | 0 | Direct |
| Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
| FabD-like | 0 | Direct |
| Class-II DAHP synthetase | 0 | Direct |
| Pyruvate kinase | 0 | Direct |
| CoaX-like | 0 | Direct |
| Molybdenum cofactor biosynthesis protein MoeB | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Malate synthase G | 0 | Direct |
| AF1104-like | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Methyltetrahydrofolate-utiluzing methyltransferases | 0 | Direct |
| Enolpyruvate transferase, EPT | 0 | Direct |
| Motor proteins | 0 | Direct |
| RBP11/RpoL | 0 | Direct |
| Sema domain | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| CAT-like | 0 | Direct |
| mRNA cap (Guanine N-7) methyltransferase | 0 | Direct |
| N-acetyl-l-glutamate kinase | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Pyruvate oxidase and decarboxylase PP module | 0 | Direct |
| ADP-specific Phosphofructokinase/Glucokinase | 0 | Direct |
| FucT-like | 0 | Direct |
| Thiamin biosynthesis kinases | 0 | Direct |
| TRAM domain | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Thiopurine S-methyltransferase | 0 | Direct |
| Legume lectins | 0 | Direct |
| Molybdopterin synthase subunit MoaE | 0 | Direct |
| Holo-(acyl carrier protein) synthase ACPS | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Receiver domain of the ethylene receptor | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| RIO1-like kinases | 0 | Direct |
| Plexin repeat | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| Methyl-coenzyme M reductase gamma chain | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Trehalose-6-phosphate synthase, OtsA | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Leucine carboxy methyltransferase Ppm1 | 0 | Direct |
| O-acetyltransferase | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| THUMP domain | 0 | Direct |
| Aspartate/ornithine carbamoyltransferase | 0 | Direct |
| Retrovirus capsid protein C-terminal domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Inosicase | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Glucose-inhibited division protein B (GidB) | 0 | Direct |
| Peptidoglycan biosynthesis glycosyltransferase MurG | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| AF1531-like | 0 | Direct |
| Phytochelatin synthase | 0 | Direct |
| Arylamine N-methyltransferase | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| Protein kinases, catalytic subunit | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| IlvH-like | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| Thiamin phosphate synthase | 0 | Direct |
| MoeA N-terminal region -like | 0 | Direct |
| Salicylic acid carboxyl methyltransferase (SAMT) | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Aspartokinase allosteric domain-like | 0 | Direct |
| Viral proteases | 0 | Direct |
| MarR-like transcriptional regulators | 0 | Direct |
| Exostosin | 0 | Direct |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | Direct |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
| RNA helicase | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| MIR domain | 0 | Direct |
| APH phosphotransferases | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Pyridoxine 5'-phosphate synthase | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
| SP1160 C-terminal domain-like | 0 | Direct |
| MoeA central domain-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| RPB6 | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| NadC C-terminal domain-like | 0 | Direct |
| Plant O-methyltransferase, N-terminal domain | 0 | Direct |
| TK-like PP module | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
| N6 adenine-specific DNA methylase, DAM | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| CTP-dependent riboflavin kinase-like | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Chemotaxis protein CheA P1 domain | 0 | Direct |
| Tpt1/KptA | 0 | Direct |
| UbiE/COQ5-like | 0 | Direct |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
| Putative methyltransferase TM0872, insert domain | 0 | Direct |
| MraW-like putative methyltransferases | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| ATP sulfurylase C-terminal domain | 0 | Direct |
| RhoA-binding domain | 0 | Direct |
| PTS system, Lactose/Cellobiose specific IIB subunit | 0 | Direct |
| glucose-1-phosphate thymidylyltransferase | 0 | Direct |
| Chalcone synthase-like | 0 | Direct |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| DsbA-like | 0 | Direct |
| double-SIS domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| DhaL-like | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme substrate-binding domain | 0 | Direct |
| CheW-like | 0 | Direct |
| Deoxyhypusine synthase, DHS | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Phytochrome-specific domain | 0 | Direct |
| LFTR-like | 0 | Direct |
| TAZ domain | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Methionine synthase SAM-binding domain | 0 | Direct |
| Immunodeficiency virus matrix proteins | 0 | Direct |
| RmsB N-terminal domain-like | 0 | Direct |
| Glutaminyl-peptide cyclotransferase-like | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| FCH domain | 0 | Direct |
| YggJ N-terminal domain-like | 0 | Direct |
| mannose-1-phosphate guanylyl transferase | 0 | Direct |
| AAT-like | 0 | Direct |
| SH3-domain | 0 | Direct |
| WGR domain | 0 | Direct |
| TK-like Pyr module | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Galactoside acetyltransferase-like | 0 | Direct |
| HAMP domain | 0 | Direct |
| Pyruvate phosphate dikinase, C-terminal domain | 0 | Direct |
| Nsp15 N-terminal domain-like | 0 | Direct |
| Poly A polymerase head domain-like | 0 | Direct |
| Pyruvate oxidase and decarboxylase Pyr module | 0 | Direct |
| PyrH-like | 0 | Direct |
| PB1 domain | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| N-acetyl transferase, NAT | 0 | Direct |
| AD-003 protein-like | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
| Sensory domain of two-component sensor kinase | 0 | Direct |
| Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| PlsX-like | 0 | Direct |
| Methionine synthase domain | 0 | Direct |
| RpiR-like | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Galactokinase | 0 | Direct |
| Cobalamin-independent methionine synthase | 0 | Direct |
| NadC N-terminal domain-like | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Pyruvate phosphate dikinase, central domain | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| DAK1 | 0 | Direct |
| RNA-dependent RNA-polymerase | 0 | Direct |
| TRM1-like | 0 | Direct |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
| N-acetylglucosaminyltransferase I | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Monomeric nicotinate phosphoribosyltransferase C-terminal domain | 0 | Direct |
| RPB5 | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| HTLV-II matrix protein | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| COMT-like | 0 | Direct |
| DNA polymerase III, beta subunit | 0 | Direct |
| Glucose permease-like | 0 | Direct |
| Swapped Polo-box domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| E-set domains of sugar-utilizing enzymes | 0 | Direct |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| SH2 domain | 0 | Direct |
| LuxQ-periplasmic domain-like | 0 | Direct |
| Amidinotransferase | 0 | Direct |
| Type II thymidine kinase | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Met-10+ protein-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Ecto-ART | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Gtf glycosyltransferase | 0 | Direct |
| Mevalonate kinase | 0 | Direct |
| ThiI-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| Autoinducer synthetase | 0 | Direct |
| NadA-like | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| ThiG-like | 0 | Direct |
| Hypothetical protein MJ0882 | 0 | Direct |
| Spermidine synthase | 0 | Direct |
| Hypothetical RNA methyltransferase domain (HRMD) | 0 | Direct |
| tRNA(1-methyladenosine) methyltransferase-like | 0 | Direct |
| Glutamine synthase adenylyltransferase GlnE, domain 2 | 0 | Direct |
| Calmodulin-like | 0 | Direct |
| HMGL-like | 0 | Direct |
| Biotin synthase | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| SRA domain-like | 0 | Direct |
| Glucokinase | 0 | Direct |
| Mycolic acid cyclopropane synthase | 0 | Direct |
| Flavin-binding PAS domain | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme catalytic domain | 0 | Direct |
| Siroheme synthase N-terminal domain-like | 0 | Direct |
| Single-domain sulfurtransferase | 0 | Direct |
| Shikimate kinase (AroK) | 0 | Direct |
| Type II DNA methylase | 0 | Direct |
| Histamine methyltransferase | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| V set domains (antibody variable domain-like) | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| PfkB-like kinase | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| YbeA-like | 0 | Direct |
| Homoserine kinase | 0 | Direct |
| Serine acetyltransferase | 0 | Direct |
| Gluconate kinase | 0 | Direct |
| Arylamine N-acetyltransferase | 0 | Direct |
| NAD kinase-like | 0 | Direct |
| MogA-like | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| DRTGG domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| UDPGT-like | 0 | Direct |
| Plant O-methyltransferase, C-terminal domain | 0 | Direct |
| ArgJ-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | Direct |
| LplA-like | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| N-myristoyl transferase, NMT | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| hypothetical RNA methyltransferase | 0 | Direct |
| mRNA capping enzyme | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| Retroviral protease (retropepsin) | 0 | Direct |
| Polygalacturonase inhibiting protein PGIP | 0 | Direct |
| YggJ C-terminal domain-like | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| RWD domain | 0 | Direct |
| MM2497-like | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Tetrapyrrole methylase | 0 | Direct |
| Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain N-terminal domain | 0 | Direct |
| PWWP domain | 0 | Direct |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
| I set domains | 0 | Direct |
| Lumazine synthase | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| Reverse transcriptase | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
| Choline kinase | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Ssp2 C-terminal domain-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| GlmU C-terminal domain-like | 0 | Direct |
| GlnE-like domain | 0 | Direct |
| Pyruvate phosphate dikinase, N-terminal domain | 0 | Direct |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
| HTS-like | 0 | Direct |
| Transketolase C-terminal domain-like | 0 | Direct |
| DNA polymerase beta-like, second domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| rRNA adenine dimethylase-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Caliciviridae-like VP | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| Guanidinoacetate methyltransferase | 0 | Direct |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | Direct |
| L domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| RNA 2'-O ribose methyltransferase substrate binding domain | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| KaiB-like | 0 | Direct |
| ATP-dependent riboflavin kinase-like | 0 | Direct |
| Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like | 0 | Direct |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| Fumble-like | 0 | Direct |
| ZZ domain | 0 | Direct |
| MoeA C-terminal domain-like | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| CoA transferase beta subunit-like | 0 | Direct |
| N-6 DNA Methylase-like | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| Pyruvate kinase beta-barrel domain | 0 | Direct |
| LIM domain | 0 | Direct |
| Glycogenin | 0 | Direct |
| Hexokinase | 0 | Direct |
| Acetokinase-like | 0 | Direct |
| Methicillin resistance protein FemA probable tRNA-binding arm | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Post formyltransferase domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Aminomethyltransferase folate-binding domain | 0 | Direct |
| alpha-1,3-galactosyltransferase-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| ATP sulfurylase catalytic domain | 0 | Direct |
| ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Polyphosphate kinase C-terminal domain | 0 | Direct |
| N5-glutamine methyltransferase, HemK | 0 | Direct |
| Poxvirus poly(A) polymerase catalytic subunit-like | 0 | Direct |
| tRNA-guanine transglycosylase | 0 | Direct |
| Pyruvate kinase, C-terminal domain | 0 | Direct |
| T7 RNA polymerase | 0 | Direct |
| Cobalamin adenosyltransferase | 0 | Direct |
| CofD-like | 0 | Direct |
| phosphatase domain of polynucleotide kinase | 0 | Direct |
| FemXAB nonribosomal peptidyltransferases | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Histidine kinase | 0 | Direct |
| tRNA(m1G37)-methyltransferase TrmD | 0 | Direct |
| Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
| Diacylglycerol kinase-like | 0 | Direct |
| Penicillin binding protein dimerisation domain | 0 | Direct |
| RNA polymerase alpha subunit dimerisation domain | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme | 0 | Direct |
| Riboflavin synthase | 0 | Direct |
| Retroviral integrase, catalytic domain | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Type II thymidine kinase zinc finger | 0 | Direct |
| WWE domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Glycine N-methyltransferase | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| PBP transglycosylase domain-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| SepSecS-like | 0 | Direct |
| IIA domain of mannitol-specific and ntr phosphotransferase EII | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Viral cysteine protease of trypsin fold | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
| AF0751-like | 0 | Direct |
| Adenosine-5'phosphosulfate kinase (APS kinase) | 0 | Direct |
| Hexose-1-phosphate uridylyltransferase | 0 | Direct |
| TrmB-like | 0 | Direct |
| Methyltransferase 10 domain | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| RNA polymerase omega subunit | 0 | Direct |
| mRNA cap methylase | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| Aminoglycoside 3-N-acetyltransferase-like | 0 | Direct |
| ATP sulfurylase N-terminal domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| Cytidylytransferase | 0 | Direct |
| Multidomain sulfurtransferase (rhodanese) | 0 | Direct |
| Carbamate kinase | 0 | Direct |
| PTS system, Fructose specific IIB subunit-like | 0 | Direct |
| UDP N-acetylglucosamine acyltransferase | 0 | Direct |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
| Transglutaminase N-terminal domain | 0 | Direct |
| BphP N-terminal domain-like | 0 | Direct |
| AstA-like | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Ketopantoate hydroxymethyltransferase PanB | 0 | Direct |
| Oligosaccharide phosphorylase | 0 | Direct |
| (Uracil-5-)-methyltransferase | 0 | Direct |
| HPr-like | 0 | Direct |
| 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE | 0 | Direct |
| ROK | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, C-terminal domain | 0 | Direct |
| Phosphotransacetylase | 3.476e-16 | Direct |
| Pleckstrin-homology domain (PH domain) | 5.205e-16 | Direct |
| Growth factor receptor domain | 0.000000000000001553 | Direct |
| Fibronectin type III | 0.000000000000003089 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0.000000000000007343 | Direct |
| PAPS reductase-like | 0.00000000000003951 | Direct |
| Synaptotagmin-like (S variant) | 0.00000000000006328 | Direct |
| Macro domain | 0.00000000000016 | Direct |
| Fic-like | 0.0000000000001812 | Direct |
| 5' to 3' exonuclease catalytic domain | 0.0000000000006981 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.000000000003428 | Direct |
| Ras-binding domain, RBD | 0.000000000004648 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0.000000000009506 | Direct |
| PHD domain | 0.00000000001655 | Direct |
| Dihydropteroate synthetase | 0.00000000002673 | Direct |
| Bromodomain | 0.0000000001391 | Direct |
| Ricin B-like | 0.0000000012 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0.00000000235 | Direct |
| Glycosyl hydrolases family 16 | 0.000000002699 | Direct |
| PHP domain | 0.00000003155 | Direct |
| RING finger domain, C3HC4 | 0.000000216 | Direct |
| Ankyrin repeat | 0.0000002778 | Direct |
| CoA-transferase family III (CaiB/BaiF) | 0.0000004187 | Direct |
| ADP-ribosylating toxins | 0.0000004582 | Direct |
| CoA transferase alpha subunit-like | 0.0000005178 | Direct |
| GGDEF domain | 0.0000006263 | Direct |
| MoCo biosynthesis proteins | 0.000003755 | Direct |
| Heme-binding PAS domain | 0.000003755 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0.000008303 | Direct |
| RelA/SpoT domain | 0.000009973 | Direct |
| Levansucrase | 0.00001071 | Direct |
| Class II viral fusion proteins C-terminal domain | 0.00001452 | Direct |
| PARP-type zinc finger | 0.00003237 | Direct |
| AlkB-like | 0.00006078 | Direct |
| GckA/TtuD-like | 0.00008576 | Direct |
| PFL-like | 0.00009152 | Direct |
| Ngr ectodomain-like | 0.0001686 | Direct |
| FHA domain | 0.0004105 | Direct |
| Transglutaminase core | 0.000485 | Direct |
| HMG-box | 0.0007131 | Direct |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.0007131 | Direct |
| PX domain | 0.0007616 | Direct |
| Second domain of FERM | 0.0007751 | Direct |
| MIT domain | 0.00118 | Inherited |
| Coronavirus NSP8-like | 0.001669 | Inherited |
| Replicase NSP9 | 0.001669 | Inherited |
| Coronavirus NSP7-like | 0.001669 | Inherited |
| Coronavirus NSP10-like | 0.001669 | Inherited |
| Chromo domain | 0.007019 | Inherited |
| Starch-binding domain | 0.007491 | Inherited |
| BadF/BadG/BcrA/BcrD-like | 0.009842 | Inherited |
| WW domain | 0.01137 | Inherited |
| NSP3A-like | 0.0194 | Inherited |
| Sterol carrier protein, SCP | 0.028 | Inherited |
| Pyruvate oxidase and decarboxylase, middle domain | 0.04103 | Inherited |
| MAPEG domain | 0.04947 | Inherited |
| HD domain | 0.05663 | Inherited |
| WD40-repeat | 0.0629 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.08016 | Inherited |
| Probable phosphatase YrbI | 0.09038 | Inherited |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.1381 | Inherited |
| Cell wall binding repeat | 0.1381 | Inherited |
| First domain of FERM | 0.147 | Inherited |
| GAF domain | 0.1508 | Inherited |
| Canonical RBD | 0.191 | Inherited |
| Third domain of FERM | 0.2521 | Inherited |
| TENA/THI-4 | 0.2621 | Inherited |
| Cobalamin (vitamin B12)-binding domain | 0.2824 | Inherited |
| Intein (protein splicing domain) | 0.3489 | Inherited |
| Homoserine dehydrogenase-like | 0.5352 | Inherited |
| MaoC-like | 0.6225 | Inherited |
| PDZ domain | 0.6225 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.6286 | Inherited |
| PLC-like (P variant) | 0.8668 | Inherited |
| DmpG/LeuA communication domain-like | 0.9531 | Inherited |
| cAMP-binding domain | 0.9653 | Inherited |
| DHN aldolase/epimerase | 0.9865 | Inherited |
| Ribonuclease H | 1 | Inherited |
| Tyrosine-dependent oxidoreductases | 1 | Inherited |
| beta-Lactamase/D-ala carboxypeptidase | 1 | Inherited |
| Crotonase-like | 1 | Inherited |
| G proteins | 1 | Inherited |
| CoA-binding domain | 1 | Inherited |
| PurM C-terminal domain-like | 1 | Inherited |
| DNA ligase | 1 | Inherited |
| BC N-terminal domain-like | 1 | Inherited |
| Anticodon-binding domain | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Decarboxylase | 1 | Inherited |
| IpsF-like | 1 | Inherited |
| ADC synthase | 1 | Inherited |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 1 | Inherited |
| Tetratricopeptide repeat (TPR) | 1 | Inherited |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 1 | Inherited |
| PurM N-terminal domain-like | 1 | Inherited |
| Elongation factors | 1 | Inherited |
| BC ATP-binding domain-like | 1 | Inherited |
| Class I glutamine amidotransferases (GAT) | 1 | Inherited |
| Extended AAA-ATPase domain | 1 | Inherited |
| Dehydroquinate synthase, DHQS | 1 | Inherited |
| EF-hand modules in multidomain proteins | 1 | Inherited |
| Dihydrofolate reductases | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| Acetyl-CoA synthetase-like | 1 | Inherited |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| mono-SIS domain | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 1 | Inherited |
| CheY-related | 1 | Inherited |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 1 | Inherited |
| FMN-linked oxidoreductases | 1 | Inherited |
| Kringle modules | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | Inherited |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 1 | Inherited |
| Shikimate dehydrogenase-like | 1 | Inherited |
| Succinyl-CoA synthetase domains | 1 | Inherited |
| Class I aldolase | 1 | Inherited |
| Nitrogenase iron protein-like | 1 | Inherited |
| BC C-terminal domain-like | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (Not in SPEO)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| GroEL apical domain-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| PilZ domain-like | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
| RNA polymerase subunits | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| KRAB domain (Kruppel-associated box) | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| RPB6/omega subunit-like | 0 | DIRECT |
| Lumazine synthase | 0 | DIRECT |
| MoeA N-terminal region -like | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| SufE/NifU | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Methyl-coenzyme M reductase subunits | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| Penicillin binding protein dimerisation domain | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Cobalamin adenosyltransferase-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| HAMP domain-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| PsbU/PolX domain-like | 0 | DIRECT |
| Thiamin phosphate synthase | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Methionine synthase activation domain-like | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| DmpA/ArgJ-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| tRNA-guanine transglycosylase | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Methionine synthase domain | 0 | DIRECT |
| GlnB-like | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| PK C-terminal domain-like | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| ThiG-like | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| Aspartate/ornithine carbamoyltransferase | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
| PHP14-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| E set domains | 0 | DIRECT |
| DAK1/DegV-like | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| Phosphohistidine domain | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| PLP-dependent transferases | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | DIRECT |
| MoeA C-terminal domain-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| NadA-like | 0 | DIRECT |
| Siroheme synthase middle domains-like | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
| PTS-regulatory domain, PRD | 0 | DIRECT |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Riboflavin kinase-like | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Malate synthase G | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Molybdopterin synthase subunit MoaE | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| NusB-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PHP domain-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| PTS system IIB component-like | 0 | DIRECT |
| Gamma-glutamyl cyclotransferase-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| TTHA0583/YokD-like | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Pyridoxine 5'-phosphate synthase | 0 | DIRECT |
| Tetrapyrrole methylase | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| AF1104-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
| RPB5-like RNA polymerase subunit | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0.000000000000001395 | DIRECT |
| Fic-like | 0.000000000000005193 | DIRECT |
| Sensory domain-like | 0.00000000000003894 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000000425 | DIRECT |
| Fibronectin type III | 0.0000000000001928 | DIRECT |
| L30e-like | 0.000000000003233 | DIRECT |
| PIN domain-like | 0.000000000003826 | DIRECT |
| ARM repeat | 0.000000000005017 | DIRECT |
| Phospholipase D/nuclease | 0.0000000002846 | DIRECT |
| Bromodomain | 0.0000000006527 | DIRECT |
| Ricin B-like lectins | 0.000000001041 | DIRECT |
| HprK N-terminal domain-like | 0.000000006496 | DIRECT |
| Chromo domain-like | 0.00000001022 | DIRECT |
| beta-beta-alpha zinc fingers | 0.00000001768 | DIRECT |
| Terpenoid synthases | 0.00000002244 | DIRECT |
| Duplicated hybrid motif | 0.0000000302 | DIRECT |
| Single hybrid motif | 0.00000003934 | DIRECT |
| RNI-like | 0.00000003974 | DIRECT |
| Glycosyl hydrolase domain | 0.00000004192 | DIRECT |
| FYVE/PHD zinc finger | 0.0000007211 | DIRECT |
| Ankyrin repeat | 0.0000008336 | DIRECT |
| CoA-transferase family III (CaiB/BaiF) | 0.000001115 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0.00003768 | DIRECT |
| GckA/TtuD-like | 0.0001509 | DIRECT |
| Homeodomain-like | 0.0003768 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0.0006328 | DIRECT |
| Second domain of FERM | 0.0009229 | DIRECT |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001044 | INHERITED FROM: Glutamate formimidoyltransferase || Transferring one-carbon groups || Hydroxymethyl-, formyl- and related transferases |
| HMG-box | 0.001044 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| SMAD/FHA domain | 0.001684 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.002344 | INHERITED FROM: Phosphatidylinositol-4,5-bisphosphate 3-kinase || Phosphatidylinositol-4-phosphate 3-kinase || Protein-serine/threonine kinases || Phosphatidylinositol 3-kinase || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase || Protein kinase C |
| Tudor/PWWP/MBT | 0.003917 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || DNA (cytosine-5-)-methyltransferase || Histone-lysine N-methyltransferase |
| Coronavirus NSP8-like | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Replicase NSP9 | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Coronavirus NSP10-like | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Coronavirus NSP7-like | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| YWTD domain | 0.005583 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases || Transferring phosphorous-containing groups |
| PX domain | 0.005685 | INHERITED FROM: Non-specific serine/threonine protein kinase || Phosphatidylinositol-4-phosphate 3-kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| MFS general substrate transporter | 0.007693 | INHERITED FROM: Spermidine synthase || Transferring alkyl or aryl groups, other than meth |
| MIT domain | 0.01044 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Ubiquitin-like | 0.01325 | INHERITED FROM: Phosphatidylinositol-4,5-bisphosphate 3-kinase || Phosphatidylinositol-4-phosphate 3-kinase || Protein-serine/threonine kinases || Protein-tyrosine kinases || Phosphatidylinositol 3-kinase || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase || Phosphotransferases with an alcohol group as accep |
| C-type lectin-like | 0.01339 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| CRAL/TRIO domain | 0.01694 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| GAF domain-like | 0.02003 | INHERITED FROM: Transferring phosphorous-containing groups || Protein-histidine kinases |
| WW domain | 0.02067 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| RNA-binding domain, RBD | 0.0238 | INHERITED FROM: Polynucleotide adenylyltransferase || tRNA (carboxymethyluridine(34)-5-O)-methyltransfer || RNA uridylyltransferase || Transferring one-carbon groups || Methyltransferases || Histone-lysine N-methyltransferase |
| Outer arm dynein light chain 1 | 0.03156 | INHERITED FROM: Protein geranylgeranyltransferase type II || Transferring alkyl or aryl groups, other than meth |
| NSP3A-like | 0.03533 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| SCP-like | 0.0383 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Propanoyl-CoA C-acyltransferase |
| Acid proteases | 0.05023 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| Hedgehog/intein (Hint) domain | 0.06263 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| MAPEG domain-like | 0.07385 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than meth |
| WD40 repeat-like | 0.1011 | INHERITED FROM: [Myosin heavy-chain] kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Homing endonucleases | 0.1267 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| SARS Nsp1-like | 0.1419 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
| Quinoprotein alcohol dehydrogenase-like | 0.143 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
| Chaperone J-domain | 0.1534 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| GTPase activation domain, GAP | 0.1534 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| DEATH domain | 0.1572 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Protein-tyrosine kinases || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase |
| Cell wall binding repeat | 0.177 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
| EF-hand | 0.228 | INHERITED FROM: Transaldolase || Non-specific serine/threonine protein kinase || Diacylglycerol kinase || Protein-serine/threonine kinases || Calcium/calmodulin-dependent protein kinase || 1-alkylglycerophosphocholine O-acetyltransferase || Transferring phosphorous-containing groups || 1-acylglycerophosphocholine O-acyltransferase |
| P-loop containing nucleoside triphosphate hydrolases | 0.2748 | INHERITED FROM: Phosphoribulokinase || tRNA(Met) cytidine acetyltransferase || Sulfotransferases || Thymidine kinase || Guanylate kinase || RNA-directed RNA polymerase || Phosphotransferases with a phosphate group as acce || Tetraacyldisaccharide 4'-kinase || Adenylate kinase || Polynucleotide 5'-hydroxyl-kinase || Adenosylcobinamide-phosphate guanylyltransferase || Transferring alkyl or aryl groups, other than meth || Shikimate kinase || dTMP kinase || Dephospho-CoA kinase || 6-phosphofructo-2-kinase || Ribosylnicotinamide kinase || mRNA (guanine-N(7)-)-methyltransferase || Phosphate acetyltransferase || Sulfate adenylyltransferase || Adenylyl-sulfate kinase || (d)CMP kinase || mRNA (nucleoside-2'-O-)-methyltransferase || Transferring phosphorous-containing groups || 2.7.1.173 || tRNA dimethylallyltransferase || Phosphotransferases with an alcohol group as accep || Uridine kinase |
| C-terminal domain of transcriptional repressors | 0.3647 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as accep |
| Cobalamin (vitamin B12)-binding domain | 0.3907 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Methionine synthase |
| FabD/lysophospholipase-like | 0.4153 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || Fatty-acyl-CoA synthase || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase || 6-deoxyerythronolide-B synthase |
| TPR-like | 0.4857 | INHERITED FROM: Dual-specificity kinases (those acting on Ser/Thr || Non-specific serine/threonine protein kinase || Protein O-GlcNAc transferase || Histone-lysine N-methyltransferase || Dual-specificity kinase || Adenosine monophosphate-protein transferase |
| Trypsin-like serine proteases | 0.5192 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || mRNA (guanine-N(7)-)-methyltransferase || mRNA (nucleoside-2'-O-)-methyltransferase || Transferring phosphorous-containing groups |
| Rubredoxin-like | 0.5359 | INHERITED FROM: Phosphotransferases with a phosphate group as acce || Adenylate kinase |
| Starch-binding domain-like | 0.5488 | INHERITED FROM: Glycosyltransferases || Hexosyltransferases || Cyclomaltodextrin glucanotransferase |
| HCP-like | 0.6021 | INHERITED FROM: [Elongation factor 2] kinase || Protein-serine/threonine kinases |
| CYTH-like phosphatases | 0.6445 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || mRNA guanylyltransferase || mRNA (guanine-N(7)-)-methyltransferase |
| NTF2-like | 0.6801 | INHERITED FROM: Protein-serine/threonine kinases || Calcium/calmodulin-dependent protein kinase || Transferring phosphorous-containing groups |
| HIT-like | 0.7477 | INHERITED FROM: UDP-glucose--hexose-1-phosphate uridylyltransferas || ATP adenylyltransferase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| UROD/MetE-like | 0.8048 | INHERITED FROM: 5-methyltetrahydropteroyltriglutamate--homocystein || Transferring one-carbon groups || Methyltransferases |
| N-(deoxy)ribosyltransferase-like | 0.8329 | INHERITED FROM: Pentosyltransferases || Nucleoside deoxyribosyltransferase |
| Thioredoxin-like | 0.8632 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than meth || Protein-histidine kinases |
| SAP domain | 0.8905 | INHERITED FROM: Pentosyltransferases || NAD(+) ADP-ribosyltransferase |
| RING/U-box | 0.9003 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Glycosyltransferases || Hexosyltransferases || Histone acetyltransferase || Mitogen-activated protein kinase kinase kinase || Cellulose synthase (UDP-forming) |
| Heme oxygenase-like | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphomethylpyrimidine kinase |
| UBA-like | 1 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| BRCT domain | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || DNA nucleotidylexotransferase |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| IpsF-like | 1 | INHERITED FROM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltrans || Nucleotidyltransferases || Transferring phosphorous-containing groups |
| Nucleotidylyl transferase | 1 | INHERITED FROM: UMP/CMP kinase || Ethanolamine-phosphate cytidylyltransferase || Nicotinamide-nucleotide adenylyltransferase || Pantetheine-phosphate adenylyltransferase || Nicotinate-nucleotide adenylyltransferase || Nucleotidyltransferases || FAD synthetase || Riboflavin kinase || Choline-phosphate cytidylyltransferase || Sulfate adenylyltransferase || Transferring phosphorous-containing groups |
| Dihydropteroate synthetase-like | 1 | INHERITED FROM: Tetrahydromethanopterin S-methyltransferase || Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine || Methyltransferases || Transferring alkyl or aryl groups, other than meth || Methionine synthase || Dihydropteroate synthase |
| MesJ substrate recognition domain-like | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl on transfer |
| dUTPase-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| Zn-dependent exopeptidases | 1 | INHERITED FROM: Glutaminyl-peptide cyclotransferase || Aminoacyltransferases |
| Kringle-like | 1 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| Terpenoid cyclases/Protein prenyltransferases | 1 | INHERITED FROM: Protein geranylgeranyltransferase type I || Protein geranylgeranyltransferase type II || Protein farnesyltransferase || Transferring alkyl or aryl groups, other than meth |
| Ribonuclease H-like | 1 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorous-containing groups |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: ATP citrate synthase || Aspartate kinase || Uroporphyrinogen-III C-methyltransferase || Fatty-acyl-CoA synthase || UDP-4-amino-4-deoxy-L-arabinose formyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Shikimate kinase || Fatty-acid synthase || 3-phosphoshikimate 1-carboxyvinyltransferase || 6-deoxyerythronolide-B synthase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| ADC-like | 1 | INHERITED FROM: Thymidine phosphorylase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase || mRNA (guanine-N(7)-)-methyltransferase |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| FAD/NAD(P)-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Transferring one-carbon groups || Methyltransferases || (FADH(2)-oxidizing) |
| Class II aaRS and biotin synthetases | 1 | INHERITED FROM: Lipoate--protein ligase || Acyltransferases || Transferring groups other than amino-acyl groups || Lipoyl(octanoyl) transferase || Lysyltransferase |
| post-HMGL domain-like | 1 | INHERITED FROM: 2-isopropylmalate synthase || Acyltransferases || Acyl groups converted into alkyl on transfer |
| GroES-like | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
| Phosphoglycerate mutase-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || 6-phosphofructo-2-kinase || Diphosphoinositol-pentakisphosphate kinase |
| FAD-binding/transporter-associated domain-like | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase |
| NagB/RpiA/CoA transferase-like | 1 | INHERITED FROM: CoA-transferases || Transferring sulfur-containing groups |
| ACP-like | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase || 6-deoxyerythronolide-B synthase |
| Pentein | 1 | INHERITED FROM: Amidinotransferases |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: Polyribonucleotide nucleotidyltransferase || mRNA guanylyltransferase || Nucleotidyltransferases || Lysyltransferase || 23S rRNA (uracil(1939)-C(5))-methyltransferase |
| FMN-linked oxidoreductases | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Transferring alkyl or aryl groups, other than meth || Phosphoglycerol geranylgeranyltransferase |
| Dehydroquinate synthase-like | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than meth || Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || Phosphotransferases with an alcohol group as accep |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Transferases for other substituted phosphate group || Phosphatidylglycerol--membrane-oligosaccharide gly |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: Cysteate synthase || Transferring alkyl or aryl groups, other than meth || Cysteine synthase |
| Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Inositol-1,3,4-trisphosphate 5/6-kinase || Inositol-hexakisphosphate kinase || ATP citrate synthase || Pyruvate, phosphate dikinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Pyruvate, water dikinase || Inositol-tetrakisphosphate 1-kinase || Diphosphoinositol-pentakisphosphate kinase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Globin-like | 1 | INHERITED FROM: Diguanylate cyclase |
| Acetyl-CoA synthetase-like | 1 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups || Acyl-[acyl-carrier-protein]--phospholipid O-acyltr |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | INHERITED FROM: Amidophosphoribosyltransferase || Glutamine--fructose-6-phosphate transaminase (isom || Transferring nitrogenous groups || Gamma-glutamyltransferase || Aminoacyltransferases || Transaminases (aminotransferases) |
| Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| HD-domain/PDEase-like | 1 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase || [Protein-PII] uridylyltransferase || Nucleotidyltransferases || Transferring phosphorous-containing groups || tRNA (cytidine(56)-2'-O)-methyltransferase |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: Nicotinamide-nucleotide adenylyltransferase || Ribosylnicotinamide kinase || DNA (cytosine-5-)-methyltransferase |
| beta-lactamase/transpeptidase-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Hexosyltransferases |
| HAD-like | 1 | INHERITED FROM: Polynucleotide 5'-hydroxyl-kinase || Alpha,alpha-trehalose-phosphate synthase (UDP-form || N-acylneuraminate cytidylyltransferase |
| Translation proteins | 1 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase |
| Glutamine synthetase/guanido kinase | 1 | INHERITED FROM: Phosphotransferases with a nitrogenous group as ac || Creatine kinase |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Thymidylate synthase |
| TGS-like | 1 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase |
| Lysozyme-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase |
| (Trans)glycosidases | 1 | INHERITED FROM: Alpha-1,3-glucan synthase || Sucrose phosphorylase || 4-alpha-glucanotransferase || 1,4-alpha-glucan branching enzyme || Dextransucrase || 2.4.99.16 || Galactinol--sucrose galactosyltransferase || Glycosyltransferases || Hexosyltransferases || Transferring other glycosyl groups || Cyclomaltodextrin glucanotransferase |
| Dimeric alpha+beta barrel | 1 | INHERITED FROM: Acyl groups converted into alkyl on transfer || Homocitrate synthase |
| SIS domain | 1 | INHERITED FROM: Glutamine--fructose-6-phosphate transaminase (isom || Transferring nitrogenous groups || Glucokinase || Transaminases (aminotransferases) |
| PFL-like glycyl radical enzymes | 1 | INHERITED FROM: Formate C-acetyltransferase || Acyltransferases || Transferring groups other than amino-acyl groups |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: Bile acid-CoA:amino acid N-acyltransferase || Acyltransferases || Transferring groups other than amino-acyl groups || Phosphatidylcholine--sterol O-acyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase || Phospholipid:diacylglycerol acyltransferase || Malonyl-CoA O-methyltransferase || Homoserine O-acetyltransferase |
| PurM C-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
| PheT/TilS domain | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| PDZ domain-like | 1 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| FAD-linked oxidases, C-terminal domain | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase || Transferring alkyl or aryl groups, other than meth |
| (Phosphotyrosine protein) phosphatases II | 1 | INHERITED FROM: mRNA guanylyltransferase |
| PreATP-grasp domain | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Fatty-acyl-CoA synthase || [Acyl-carrier-protein] S-acetyltransferase |
| Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: Xyloglucan:xyloglucosyl transferase || Glycosyltransferases || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Hexosyltransferases |
| SGNH hydrolase | 1 | INHERITED FROM: N-acylneuraminate cytidylyltransferase |
| tRNA-binding arm | 1 | INHERITED FROM: glycyltransferase |
| Clavaminate synthase-like | 1 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransfer || RNA-directed RNA polymerase |
| Ribonuclease Rh-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| SAICAR synthase-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Inositol-trisphosphate 3-kinase || 1-phosphatidylinositol-3-phosphate 5-kinase || 1-phosphatidylinositol-5-phosphate 4-kinase || Inositol-polyphosphate multikinase || 1-phosphatidylinositol-4-phosphate 5-kinase || Phosphotransferases with an alcohol group as accep |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: Thymidine kinase || NAD(+) ADP-ribosyltransferase || Transferring phosphorous-containing groups || Phosphotransferases with an alcohol group as accep |
| Galactose-binding domain-like | 1 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| PurM N-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
| Zinc beta-ribbon | 1 | INHERITED FROM: Nucleotidyltransferases || DNA-directed RNA polymerase |
| Nucleotide cyclase | 1 | INHERITED FROM: Diguanylate cyclase |
| RmlC-like cupins | 1 | INHERITED FROM: Mannose-1-phosphate guanylyltransferase |
| Arabinanase/levansucrase/invertase | 1 | INHERITED FROM: Hexosyltransferases || Levansucrase |
| Families 57/38 glycoside transferase middle domain | 1 | INHERITED FROM: 1,4-alpha-glucan branching enzyme || Hexosyltransferases |
| Macro domain-like | 1 | INHERITED FROM: RNA-directed RNA polymerase || NAD(+) ADP-ribosyltransferase || Nucleotidyltransferases |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | INHERITED FROM: tRNA (guanine(37)-N(1))-methyltransferase || 6-phosphofructokinase |
| Adenine nucleotide alpha hydrolases-like | 1 | INHERITED FROM: Sulfurtransferases || Nucleotidyltransferases || FAD synthetase || Transferring sulfur-containing groups || Sulfate adenylyltransferase || tRNA sulfurtransferase |
| Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Homoserine O-succinyltransferase || Acyltransferases || Transferring groups other than amino-acyl groups || Aminodeoxychorismate synthase |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine || Dihydropteroate synthase |
| Six-hairpin glycosidases | 1 | INHERITED FROM: 4-alpha-glucanotransferase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Nucleotide-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Methyltransferases |
| ADC synthase | 1 | INHERITED FROM: Transferring nitrogenous groups || Aminodeoxychorismate synthase || Transaminases (aminotransferases) |
| Glycoside hydrolase/deacetylase | 1 | INHERITED FROM: Beta-galactoside alpha-2,6-sialyltransferase || 1,4-alpha-glucan branching enzyme || Transferring other glycosyl groups |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Caffeate O-methyltransferase || 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransfera || Acetylserotonin O-methyltransferase || CTP-dependent riboflavin kinase || Isoflavone 4'-O-methyltransferase || Isoflavone 7-O-methyltransferase || Quercetin 3-O-methyltransferase || Histone acetyltransferase || (Iso)eugenol O-methyltransferase |
| Cysteine proteinases | 1 | INHERITED FROM: Arylamine N-acetyltransferase || RNA-directed RNA polymerase || Protein-glutamine gamma-glutamyltransferase || Acyltransferases || Glutathione gamma-glutamylcysteinyltransferase || Aminoacyltransferases |
| cAMP-binding domain-like | 1 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
| FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Methyltransferases |
| Riboflavin synthase domain-like | 1 | INHERITED FROM: Riboflavin synthase |
| CheY-like | 1 | INHERITED FROM: Transferring phosphorous-containing groups || Protein-histidine kinases |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| GroEL apical domain-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| SH3-domain | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| AF1531-like | 0 | Direct |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| PilZ domain-like | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
| PH domain-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
| RNA polymerase subunits | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Plexin repeat | 0 | Direct |
| KRAB domain (Kruppel-associated box) | 0 | Direct |
| SET domain | 0 | Direct |
| L27 domain | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| RPB6/omega subunit-like | 0 | Direct |
| Lumazine synthase | 0 | Direct |
| MoeA N-terminal region -like | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| SufE/NifU | 0 | Direct |
| PRTase-like | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Methyl-coenzyme M reductase subunits | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| Penicillin binding protein dimerisation domain | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Cobalamin adenosyltransferase-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Aldolase | 0 | Direct |
| HAMP domain-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| PsbU/PolX domain-like | 0 | Direct |
| Thiamin phosphate synthase | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| CheW-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
| Notch domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Methionine synthase activation domain-like | 0 | Direct |
| L domain-like | 0 | Direct |
| DmpA/ArgJ-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Sema domain | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| Histone-fold | 0 | Direct |
| DNA clamp | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| tRNA-guanine transglycosylase | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Methionine synthase domain | 0 | Direct |
| GlnB-like | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| PUA domain-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Poly(A) polymerase catalytic subunit-like | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| PK C-terminal domain-like | 0 | Direct |
| ACT-like | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| ThiG-like | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| Aspartate/ornithine carbamoyltransferase | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
| PHP14-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| E set domains | 0 | Direct |
| DAK1/DegV-like | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| Phosphohistidine domain | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| PLP-dependent transferases | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Trm112p-like | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | Direct |
| MoeA C-terminal domain-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| NadA-like | 0 | Direct |
| Siroheme synthase middle domains-like | 0 | Direct |
| Cyclin-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| DhaL-like | 0 | Direct |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
| PTS-regulatory domain, PRD | 0 | Direct |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Riboflavin kinase-like | 0 | Direct |
| Formyltransferase | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Putative methyltransferase TM0872, insert domain | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| EndoU-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| CofD-like | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Malate synthase G | 0 | Direct |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | Direct |
| WWE domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| MIR domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Molybdopterin synthase subunit MoaE | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| NusB-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PHP domain-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| PTS system IIB component-like | 0 | Direct |
| Gamma-glutamyl cyclotransferase-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
| HPr-like | 0 | Direct |
| TTHA0583/YokD-like | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Pyridoxine 5'-phosphate synthase | 0 | Direct |
| Tetrapyrrole methylase | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| KA1-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| TAZ domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| AF1104-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| SH2 domain | 0 | Direct |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
| RPB5-like RNA polymerase subunit | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0.000000000000001395 | Direct |
| Fic-like | 0.000000000000005193 | Direct |
| Sensory domain-like | 0.00000000000003894 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000000425 | Direct |
| Fibronectin type III | 0.0000000000001928 | Direct |
| L30e-like | 0.000000000003233 | Direct |
| PIN domain-like | 0.000000000003826 | Direct |
| ARM repeat | 0.000000000005017 | Direct |
| Phospholipase D/nuclease | 0.0000000002846 | Direct |
| Bromodomain | 0.0000000006527 | Direct |
| Ricin B-like lectins | 0.000000001041 | Direct |
| HprK N-terminal domain-like | 0.000000006496 | Direct |
| Chromo domain-like | 0.00000001022 | Direct |
| beta-beta-alpha zinc fingers | 0.00000001768 | Direct |
| Terpenoid synthases | 0.00000002244 | Direct |
| Duplicated hybrid motif | 0.0000000302 | Direct |
| Single hybrid motif | 0.00000003934 | Direct |
| RNI-like | 0.00000003974 | Direct |
| Glycosyl hydrolase domain | 0.00000004192 | Direct |
| FYVE/PHD zinc finger | 0.0000007211 | Direct |
| Ankyrin repeat | 0.0000008336 | Direct |
| CoA-transferase family III (CaiB/BaiF) | 0.000001115 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0.00003768 | Direct |
| GckA/TtuD-like | 0.0001509 | Direct |
| Homeodomain-like | 0.0003768 | Direct |
| beta-sandwich domain of Sec23/24 | 0.0006328 | Direct |
| Second domain of FERM | 0.0009229 | Direct |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001044 | Inherited |
| HMG-box | 0.001044 | Inherited |
| SMAD/FHA domain | 0.001684 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.002344 | Inherited |
| Tudor/PWWP/MBT | 0.003917 | Inherited |
| Coronavirus NSP8-like | 0.004174 | Inherited |
| Replicase NSP9 | 0.004174 | Inherited |
| Coronavirus NSP10-like | 0.004174 | Inherited |
| Coronavirus NSP7-like | 0.004174 | Inherited |
| YWTD domain | 0.005583 | Inherited |
| PX domain | 0.005685 | Inherited |
| MFS general substrate transporter | 0.007693 | Inherited |
| MIT domain | 0.01044 | Inherited |
| Ubiquitin-like | 0.01325 | Inherited |
| C-type lectin-like | 0.01339 | Inherited |
| CRAL/TRIO domain | 0.01694 | Inherited |
| GAF domain-like | 0.02003 | Inherited |
| WW domain | 0.02067 | Inherited |
| RNA-binding domain, RBD | 0.0238 | Inherited |
| Outer arm dynein light chain 1 | 0.03156 | Inherited |
| NSP3A-like | 0.03533 | Inherited |
| SCP-like | 0.0383 | Inherited |
| Acid proteases | 0.05023 | Inherited |
| Hedgehog/intein (Hint) domain | 0.06263 | Inherited |
| MAPEG domain-like | 0.07385 | Inherited |
| WD40 repeat-like | 0.1011 | Inherited |
| Homing endonucleases | 0.1267 | Inherited |
| SARS Nsp1-like | 0.1419 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.143 | Inherited |
| Chaperone J-domain | 0.1534 | Inherited |
| GTPase activation domain, GAP | 0.1534 | Inherited |
| DEATH domain | 0.1572 | Inherited |
| Cell wall binding repeat | 0.177 | Inherited |
| EF-hand | 0.228 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.2748 | Inherited |
| C-terminal domain of transcriptional repressors | 0.3647 | Inherited |
| Cobalamin (vitamin B12)-binding domain | 0.3907 | Inherited |
| FabD/lysophospholipase-like | 0.4153 | Inherited |
| TPR-like | 0.4857 | Inherited |
| Trypsin-like serine proteases | 0.5192 | Inherited |
| Rubredoxin-like | 0.5359 | Inherited |
| Starch-binding domain-like | 0.5488 | Inherited |
| HCP-like | 0.6021 | Inherited |
| CYTH-like phosphatases | 0.6445 | Inherited |
| NTF2-like | 0.6801 | Inherited |
| HIT-like | 0.7477 | Inherited |
| UROD/MetE-like | 0.8048 | Inherited |
| N-(deoxy)ribosyltransferase-like | 0.8329 | Inherited |
| Thioredoxin-like | 0.8632 | Inherited |
| SAP domain | 0.8905 | Inherited |
| RING/U-box | 0.9003 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| UBA-like | 1 | Inherited |
| BRCT domain | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| IpsF-like | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Dihydropteroate synthetase-like | 1 | Inherited |
| MesJ substrate recognition domain-like | 1 | Inherited |
| Succinyl-CoA synthetase domains | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Zn-dependent exopeptidases | 1 | Inherited |
| Kringle-like | 1 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 1 | Inherited |
| Ribonuclease H-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| ADC-like | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| FAD/NAD(P)-binding domain | 1 | Inherited |
| Class II aaRS and biotin synthetases | 1 | Inherited |
| post-HMGL domain-like | 1 | Inherited |
| GroES-like | 1 | Inherited |
| Phosphoglycerate mutase-like | 1 | Inherited |
| FAD-binding/transporter-associated domain-like | 1 | Inherited |
| NagB/RpiA/CoA transferase-like | 1 | Inherited |
| ACP-like | 1 | Inherited |
| Pentein | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| FMN-linked oxidoreductases | 1 | Inherited |
| Dehydroquinate synthase-like | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Globin-like | 1 | Inherited |
| Acetyl-CoA synthetase-like | 1 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | Inherited |
| Rudiment single hybrid motif | 1 | Inherited |
| HD-domain/PDEase-like | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| beta-lactamase/transpeptidase-like | 1 | Inherited |
| HAD-like | 1 | Inherited |
| Translation proteins | 1 | Inherited |
| Glutamine synthetase/guanido kinase | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Lysozyme-like | 1 | Inherited |
| (Trans)glycosidases | 1 | Inherited |
| Dimeric alpha+beta barrel | 1 | Inherited |
| SIS domain | 1 | Inherited |
| PFL-like glycyl radical enzymes | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| PurM C-terminal domain-like | 1 | Inherited |
| PheT/TilS domain | 1 | Inherited |
| PDZ domain-like | 1 | Inherited |
| FAD-linked oxidases, C-terminal domain | 1 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 1 | Inherited |
| PreATP-grasp domain | 1 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | Inherited |
| Concanavalin A-like lectins/glucanases | 1 | Inherited |
| SGNH hydrolase | 1 | Inherited |
| tRNA-binding arm | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
| SAICAR synthase-like | 1 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
| Galactose-binding domain-like | 1 | Inherited |
| PurM N-terminal domain-like | 1 | Inherited |
| Zinc beta-ribbon | 1 | Inherited |
| Nucleotide cyclase | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| Arabinanase/levansucrase/invertase | 1 | Inherited |
| Families 57/38 glycoside transferase middle domain | 1 | Inherited |
| Macro domain-like | 1 | Inherited |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | Inherited |
| Adenine nucleotide alpha hydrolases-like | 1 | Inherited |
| Phosphoglucomutase, C-terminal domain | 1 | Inherited |
| Class I glutamine amidotransferase-like | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
| Six-hairpin glycosidases | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Nucleotide-binding domain | 1 | Inherited |
| ADC synthase | 1 | Inherited |
| Glycoside hydrolase/deacetylase | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| cAMP-binding domain-like | 1 | Inherited |
| FAD-linked reductases, C-terminal domain | 1 | Inherited |
| Riboflavin synthase domain-like | 1 | Inherited |
| CheY-like | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (Not in SPEO)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
63520,63520
63520 - PTS-regulatory domain, PRD
63520 - PTS-regulatory domain, PRD | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54928,51197
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
46585,49562
46585 - HR1 repeat
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
103190,158472
103190 - Sensory domain-like
158472 - HAMP domain-like | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
56672,90234
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
56112,50978
56112 - Protein kinase-like (PK-like)
50978 - WD40 repeat-like | 0 | DIRECT |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56112,48403
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat | 0 | DIRECT |
53218,63867
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | DIRECT |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | DIRECT |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | DIRECT |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
81301,81891
81301 - Nucleotidyltransferase
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49899,56112
49899 - Concanavalin A-like lectins/glucanases
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
46689,53697
46689 - Homeodomain-like
53697 - SIS domain | 0 | DIRECT |
53067,56112
53067 - Actin-like ATPase domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48452,140931
48452 - TPR-like
140931 - Fic-like | 0 | DIRECT |
53633,55021
53633 - Carbamate kinase-like
55021 - ACT-like | 0 | DIRECT |
64484,64484
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
51726,51726
51726 - UROD/MetE-like
51726 - UROD/MetE-like | 0 | DIRECT |
53335,51905
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
55890,55874
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
52418,54680
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
52210,51735
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
55681,82649
55681 - Class II aaRS and biotin synthetases
82649 - SufE/NifU | 0 | DIRECT |
49594,52075
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
52075 - Outer arm dynein light chain 1 | 0 | DIRECT |
56112,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
47413,53335
47413 - lambda repressor-like DNA-binding domains
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
56672,51294
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | DIRECT |
54197,54197
54197 - HIT-like
54197 - HIT-like | 0 | DIRECT |
47986,56112
47986 - DEATH domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54593,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase | 0 | DIRECT |
52047,56112
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
88697,75217
88697 - PUA domain-like
75217 - alpha/beta knot | 0 | DIRECT |
51569,47473
51569 - Aldolase
47473 - EF-hand | 0 | DIRECT |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
52058,56112
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
55083,51717
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
54675,51690
54675 - Nicotinate/Quinolinate PRTase N-terminal domain-like
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
56553,55257
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase | 0 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
47648,52418
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
69593,47473
69593 - Glycerol-3-phosphate (1)-acyltransferase
47473 - EF-hand | 0 | DIRECT |
48439,49594
48439 - Protein prenylyltransferase
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
82282,51717
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
55257,47789
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
54160,82199
54160 - Chromo domain-like
82199 - SET domain | 0 | DIRECT |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
63380,63380
63380 - Riboflavin synthase domain-like
63380 - Riboflavin synthase domain-like | 0 | DIRECT |
116846,116846
116846 - MIT domain
116846 - MIT domain | 0 | DIRECT |
50692,47648
50692 - ADC-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
140356,143724
140356 - PPK N-terminal domain-like
143724 - PHP14-like | 0 | DIRECT |
52540,88697
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like | 0 | DIRECT |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
56219,56672
56219 - DNase I-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
55874,50341
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
143437,53335
143437 - THUMP domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
50998,56112
50998 - Quinoprotein alcohol dehydrogenase-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51391,53613
51391 - Thiamin phosphate synthase
53613 - Ribokinase-like | 0 | DIRECT |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
55608,56672
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | DIRECT |
53597,55831
53597 - Dihydrofolate reductase-like
55831 - Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
158472,47384
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
82549,101473
82549 - DAK1/DegV-like
101473 - DhaL-like | 0 | DIRECT |
53448,51182
53448 - Nucleotide-diphospho-sugar transferases
51182 - RmlC-like cupins | 0 | DIRECT |
88697,52374
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
46915,54211
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
88697,82199
88697 - PUA domain-like
82199 - SET domain | 0 | DIRECT |
53335,50249
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
53335,53383
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53383 - PLP-dependent transferases | 0 | DIRECT |
46785,82114
46785 - "Winged helix" DNA-binding domain
82114 - Riboflavin kinase-like | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
57667,54928
57667 - beta-beta-alpha zinc fingers
54928 - RNA-binding domain, RBD | 0 | DIRECT |
49562,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | DIRECT |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | DIRECT |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
47212,56112
47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
55785,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like | 0 | DIRECT |
47391,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47384,55874
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
103473,53335
103473 - MFS general substrate transporter
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
51735,52540
51735 - NAD(P)-binding Rossmann-fold domains
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
55781,47384
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | DIRECT |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
52540,47648
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
53850,54782
53850 - Periplasmic binding protein-like II
54782 - Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,103243
56112 - Protein kinase-like (PK-like)
103243 - KA1-like | 0 | DIRECT |
52540,57802
52540 - P-loop containing nucleoside triphosphate hydrolases
57802 - Rubredoxin-like | 0 | DIRECT |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
53155,46767
53155 - Methylated DNA-protein cysteine methyltransferase domain
46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
50465,52540
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54171,82199
54171 - DNA-binding domain
82199 - SET domain | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
57889,111331
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
50249,89550
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
69360,51445
69360 - Cell wall binding repeat
51445 - (Trans)glycosidases | 0 | DIRECT |
56037,53271
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | DIRECT |
55931,48034
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
55979,55979
55979 - DNA clamp
55979 - DNA clamp | 0 | DIRECT |
51621,52935
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | DIRECT |
52402,52821
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
63999,63862
63999 - Thiamin pyrophosphokinase, catalytic domain
63862 - Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
53448,52266
53448 - Nucleotide-diphospho-sugar transferases
52266 - SGNH hydrolase | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56235,53271
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53271 - PRTase-like | 0 | DIRECT |
53448,51161
53448 - Nucleotide-diphospho-sugar transferases
51161 - Trimeric LpxA-like enzymes | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
53335,53335
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
53448,53448
53448 - Nucleotide-diphospho-sugar transferases
53448 - Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
55785,47384
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0 | DIRECT |
57850,57933
57850 - RING/U-box
57933 - TAZ domain | 0 | DIRECT |
53790,53335
53790 - Tetrapyrrole methylase
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57850,48371
57850 - RING/U-box
48371 - ARM repeat | 0 | DIRECT |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
55315,75217
55315 - L30e-like
75217 - alpha/beta knot | 0 | DIRECT |
53633,53720
53633 - Carbamate kinase-like
53720 - ALDH-like | 0 | DIRECT |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
55052,47384
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
55781,55785
55781 - GAF domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
52087,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat | 0 | DIRECT |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | DIRECT |
47226,55052
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA | 0 | DIRECT |
53448,69765
53448 - Nucleotide-diphospho-sugar transferases
69765 - IpsF-like | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,53271
52540 - P-loop containing nucleoside triphosphate hydrolases
53271 - PRTase-like | 0 | DIRECT |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
46785,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
56112,55681
56112 - Protein kinase-like (PK-like)
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
52935,52009
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
75217,54593
75217 - alpha/beta knot
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
53271,53271
53271 - PRTase-like
53271 - PRTase-like | 0 | DIRECT |
51621,55804
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
55073,56112
55073 - Nucleotide cyclase
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | DIRECT |
53850,54913
53850 - Periplasmic binding protein-like II
54913 - GlnB-like | 0 | DIRECT |
56112,50998
56112 - Protein kinase-like (PK-like)
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
52540,75138
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
56672,55608
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | DIRECT |
47831,52009
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
52113,47802
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
47769,56399
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
64268,56112
64268 - PX domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51230,52777
51230 - Single hybrid motif
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
53448,56784
53448 - Nucleotide-diphospho-sugar transferases
56784 - HAD-like | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
56112,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain | 0 | DIRECT |
88697,53335
88697 - PUA domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
81593,81891
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
57440,56112
57440 - Kringle-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47807,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | DIRECT |
54277,56112
54277 - CAD & PB1 domains
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
52540,55729
52540 - P-loop containing nucleoside triphosphate hydrolases
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
102114,55729
102114 - Radical SAM enzymes
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
52009,51621
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
53633,88697
53633 - Carbamate kinase-like
88697 - PUA domain-like | 0 | DIRECT |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
47802,81585
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | DIRECT |
56112,90257
56112 - Protein kinase-like (PK-like)
90257 - Myosin rod fragments | 0 | DIRECT |
55594,47831
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,54928
56112 - Protein kinase-like (PK-like)
54928 - RNA-binding domain, RBD | 0 | DIRECT |
89000,110921
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
52374,82114
52374 - Nucleotidylyl transferase
82114 - Riboflavin kinase-like | 0 | DIRECT |
55088,48081
55088 - Methyl-coenzyme M reductase subunits
48081 - Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
55729,47370
55729 - Acyl-CoA N-acyltransferases (Nat)
47370 - Bromodomain | 0 | DIRECT |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
101288,101288
101288 - L27 domain
101288 - L27 domain | 0 | DIRECT |
46785,56112
46785 - "Winged helix" DNA-binding domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
52833,47384
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
53756,53756
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53756 - UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
47807,53098
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | DIRECT |
54277,57889
54277 - CAD & PB1 domains
57889 - Cysteine-rich domain | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51717,47644
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
102114,53383
102114 - Radical SAM enzymes
53383 - PLP-dependent transferases | 0 | DIRECT |
52172,52172
52172 - CheY-like
52172 - CheY-like | 0 | DIRECT |
51735,48256
51735 - NAD(P)-binding Rossmann-fold domains
48256 - Citrate synthase | 0 | DIRECT |
56112,54427
56112 - Protein kinase-like (PK-like)
54427 - NTF2-like | 0 | DIRECT |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
81891,109604
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
50044,53335
50044 - SH3-domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
56112,50985
56112 - Protein kinase-like (PK-like)
50985 - RCC1/BLIP-II | 0 | DIRECT |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
69593,56801
69593 - Glycerol-3-phosphate (1)-acyltransferase
56801 - Acetyl-CoA synthetase-like | 0 | DIRECT |
56042,53328
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | DIRECT |
53633,55729
53633 - Carbamate kinase-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
50729,69322
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
52540,81301
52540 - P-loop containing nucleoside triphosphate hydrolases
81301 - Nucleotidyltransferase | 0 | DIRECT |
103190,55785
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
56112,52540
56112 - Protein kinase-like (PK-like)
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55781,55874
55781 - GAF domain-like
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53850,55785
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
54160,53335
54160 - Chromo domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
56059,52009
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | DIRECT |
56112,48452
56112 - Protein kinase-like (PK-like)
48452 - TPR-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52317,47648
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55785,55890
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | DIRECT |
56112,50044
56112 - Protein kinase-like (PK-like)
50044 - SH3-domain | 0 | DIRECT |
55804,52794
55804 - Phoshotransferase/anion transport protein
52794 - PTS system IIB component-like | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
143724,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
50156,56112
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53335,81799
53335 - S-adenosyl-L-methionine-dependent methyltransferases
81799 - Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
52113,142921
52113 - BRCT domain
142921 - WGR domain-like | 0 | DIRECT |
63520,52794
63520 - PTS-regulatory domain, PRD
52794 - PTS system IIB component-like | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
52794,52794
52794 - PTS system IIB component-like
52794 - PTS system IIB component-like | 0 | DIRECT |
52242,56507
52242 - Cobalamin (vitamin B12)-binding domain
56507 - Methionine synthase activation domain-like | 0 | DIRECT |
103190,47384
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
50800,51621
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
82199,81822
82199 - SET domain
81822 - RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
88798,50249
88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
56112,47473
56112 - Protein kinase-like (PK-like)
47473 - EF-hand | 0 | DIRECT |
75615,53790
75615 - Siroheme synthase middle domains-like
53790 - Tetrapyrrole methylase | 0 | DIRECT |
51569,54909
51569 - Aldolase
54909 - Dimeric alpha+beta barrel | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
48403,82199
48403 - Ankyrin repeat
82199 - SET domain | 0 | DIRECT |
63882,53218
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
46785,53335
46785 - "Winged helix" DNA-binding domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
54791,50249
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
55666,46915
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
53271,51366
53271 - PRTase-like
51366 - Ribulose-phoshate binding barrel | 0 | DIRECT |
52317,56322
52317 - Class I glutamine amidotransferase-like
56322 - ADC synthase | 0 | DIRECT |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | DIRECT |
55021,55021
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
55729,46589
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm | 0 | DIRECT |
55116,55116
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
54160,55729
54160 - Chromo domain-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
51294,56672
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases | 0 | DIRECT |
81301,81593
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
49265,63825
49265 - Fibronectin type III
63825 - YWTD domain | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
89550,53098
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
48013,53335
48013 - NusB-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
47644,52242
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain | 0 | DIRECT |
47757,53335
47757 - Chemotaxis receptor methyltransferase CheR, N-terminal domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
55116,101262
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
101262 - Methenyltetrahydrofolate cyclohydrolase-like | 0 | DIRECT |
55874,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | DIRECT |
55666,54791
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
82199,48452
82199 - SET domain
48452 - TPR-like | 0 | DIRECT |
57774,52540
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55604,51261
55604 - Glucose permease domain IIB
51261 - Duplicated hybrid motif | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
75217,75217
75217 - alpha/beta knot
75217 - alpha/beta knot | 0 | DIRECT |
56112,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | DIRECT |
52540,57716
52540 - P-loop containing nucleoside triphosphate hydrolases
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
52172,47226
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
52794,55804
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
63825,49265
63825 - YWTD domain
49265 - Fibronectin type III | 0 | DIRECT |
56519,56601
56519 - Penicillin binding protein dimerisation domain
56601 - beta-lactamase/transpeptidase-like | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
56235,53697
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53697 - SIS domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
143437,52402
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 0 | DIRECT |
81631,57756
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
51230,51230
51230 - Single hybrid motif
51230 - Single hybrid motif | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
75138,53659
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
53850,56112
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,52799
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
55021,51735
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 0 | DIRECT |
75217,109604
75217 - alpha/beta knot
109604 - HD-domain/PDEase-like | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
55112,55112
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | DIRECT |
51197,53335
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
81585,81301
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
50486,51735
50486 - FMT C-terminal domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53901,55718
53901 - Thiolase-like
55718 - SCP-like | 0 | DIRECT |
109604,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | DIRECT |
51735,75615
51735 - NAD(P)-binding Rossmann-fold domains
75615 - Siroheme synthase middle domains-like | 0 | DIRECT |
53955,56601
53955 - Lysozyme-like
56601 - beta-lactamase/transpeptidase-like | 0 | DIRECT |
82185,82199
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82199 - SET domain | 0 | DIRECT |
52949,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,53335
50249 - Nucleic acid-binding proteins
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
46589,55729
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
81995,56112
81995 - beta-sandwich domain of Sec23/24
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | DIRECT |
158472,55785
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000000425 | DIRECT |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0.00000000001599 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.00000000001599 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.00000000003174 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0.0000000000383 | DIRECT |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0.000000006496 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.00000002662 | DIRECT |
81296,49452
81296 - E set domains
49452 - Starch-binding domain-like | 0.0000001308 | DIRECT |
51011,81296
51011 - Glycosyl hydrolase domain
81296 - E set domains | 0.0000001308 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.000000555 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.0000009672 | DIRECT |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.00000263 | DIRECT |
51206,56112
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000263 | DIRECT |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.000002828 | DIRECT |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.000006248 | DIRECT |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00001836 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.00003052 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0.00004837 | DIRECT |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0.00006281 | DIRECT |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.00006634 | DIRECT |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.0001117 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0002365 | DIRECT |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.001044 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || Acyltransferases || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.002297 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0.003403 | INHERITED FROM: Ethanolamine-phosphate cytidylyltransferase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
51445,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat | 0.005583 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
69360,69360
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0.005583 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.005691 | INHERITED FROM: RNA-directed RNA polymerase || Polynucleotide 5'-hydroxyl-kinase || Transferring alkyl or aryl groups, other than meth || Nucleotidyltransferases || mRNA (guanine-N(7)-)-methyltransferase || mRNA (nucleoside-2'-O-)-methyltransferase || tRNA dimethylallyltransferase |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0.007693 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.009091 | INHERITED FROM: Transferring one-carbon groups || Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.01001 | INHERITED FROM: CoA-transferases || Transferring sulfur-containing groups |
51246,55326
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0.01891 | INHERITED FROM: Transferring one-carbon groups || Phosphoribosylglycinamide formyltransferase || Hydroxymethyl-, formyl- and related transferases |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.02083 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases || Transferring phosphorous-containing groups |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.02598 | INHERITED FROM: Protein-tyrosine kinases || Transferring phosphorous-containing groups || Non-specific protein-tyrosine kinase |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0726 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.0726 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.07638 | INHERITED FROM: Nucleotidyltransferases |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.1419 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.1534 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.1534 | INHERITED FROM: Glycosyltransferases || Hexosyltransferases |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.3178 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0.3647 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as accep |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.4337 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases || Transferring phosphorous-containing groups |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.6445 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
47336,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.8261 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.8329 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase || Selenide, water dikinase |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 1 | INHERITED FROM: Lysyltransferase || Aminoacyltransferases |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 1 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase || Transferring phosphorous-containing groups |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
53383,53383
53383 - PLP-dependent transferases
53383 - PLP-dependent transferases | 1 | INHERITED FROM: Methionine S-methyltransferase |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 1 | INHERITED FROM: 2-isopropylmalate synthase || Acyltransferases || Acyl groups converted into alkyl on transfer |
52402,82829
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 1 | INHERITED FROM: 1,4-alpha-glucan branching enzyme || 2.4.99.16 || Glycosyltransferases || Hexosyltransferases || Transferring other glycosyl groups || Cyclomaltodextrin glucanotransferase |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 1 | INHERITED FROM: Hexosyltransferases |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | INHERITED FROM: mRNA guanylyltransferase |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
56042,55326
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
82829,56037
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methylt || Methyltransferases |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase || Transferring alkyl or aryl groups, other than meth |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 1 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 1 | INHERITED FROM: Beta-ketoacyl-acyl-carrier-protein synthase I |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl on transfer |
55620,55620
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine || Dihydropteroate synthase |
57783,57783
57783 - Zinc beta-ribbon
57783 - Zinc beta-ribbon | 1 | INHERITED FROM: DNA-directed RNA polymerase |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-acyl-carrier-protein synthase I || [Acyl-carrier-protein] S-acetyltransferase || Fatty-acid synthase |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 1 | INHERITED FROM: Protein-histidine kinases |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
63520,63520
63520 - PTS-regulatory domain, PRD
63520 - PTS-regulatory domain, PRD | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
54928,51197
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
57903,63748
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT | 0 | Direct |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
46585,49562
46585 - HR1 repeat
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
103190,158472
103190 - Sensory domain-like
158472 - HAMP domain-like | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
56672,90234
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
56112,50978
56112 - Protein kinase-like (PK-like)
50978 - WD40 repeat-like | 0 | Direct |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56112,48403
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat | 0 | Direct |
53218,63867
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | Direct |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | Direct |
52949,52949
52949 - Macro domain-like
52949 - Macro domain-like | 0 | Direct |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
81301,81891
81301 - Nucleotidyltransferase
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49899,56112
49899 - Concanavalin A-like lectins/glucanases
56112 - Protein kinase-like (PK-like) | 0 | Direct |
46689,53697
46689 - Homeodomain-like
53697 - SIS domain | 0 | Direct |
53067,56112
53067 - Actin-like ATPase domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48452,140931
48452 - TPR-like
140931 - Fic-like | 0 | Direct |
53633,55021
53633 - Carbamate kinase-like
55021 - ACT-like | 0 | Direct |
64484,64484
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
51726,51726
51726 - UROD/MetE-like
51726 - UROD/MetE-like | 0 | Direct |
53335,51905
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51905 - FAD/NAD(P)-binding domain | 0 | Direct |
55890,55874
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
52418,54680
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
52210,51735
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
55681,82649
55681 - Class II aaRS and biotin synthetases
82649 - SufE/NifU | 0 | Direct |
49594,52075
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
52075 - Outer arm dynein light chain 1 | 0 | Direct |
56112,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
47413,53335
47413 - lambda repressor-like DNA-binding domains
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
56672,51294
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | Direct |
54197,54197
54197 - HIT-like
54197 - HIT-like | 0 | Direct |
47986,56112
47986 - DEATH domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54593,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase | 0 | Direct |
52047,56112
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
88697,75217
88697 - PUA domain-like
75217 - alpha/beta knot | 0 | Direct |
51569,47473
51569 - Aldolase
47473 - EF-hand | 0 | Direct |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
52058,56112
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
55083,51717
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | Direct |
54675,51690
54675 - Nicotinate/Quinolinate PRTase N-terminal domain-like
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
56553,55257
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase | 0 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
47648,52418
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
69593,47473
69593 - Glycerol-3-phosphate (1)-acyltransferase
47473 - EF-hand | 0 | Direct |
48439,49594
48439 - Protein prenylyltransferase
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
82282,51717
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like | 0 | Direct |
55257,47789
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
54160,82199
54160 - Chromo domain-like
82199 - SET domain | 0 | Direct |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
63380,63380
63380 - Riboflavin synthase domain-like
63380 - Riboflavin synthase domain-like | 0 | Direct |
116846,116846
116846 - MIT domain
116846 - MIT domain | 0 | Direct |
50692,47648
50692 - ADC-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
140356,143724
140356 - PPK N-terminal domain-like
143724 - PHP14-like | 0 | Direct |
52540,88697
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like | 0 | Direct |
82199,57903
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
56219,56672
56219 - DNase I-like
56672 - DNA/RNA polymerases | 0 | Direct |
55874,50341
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
143437,53335
143437 - THUMP domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
50998,56112
50998 - Quinoprotein alcohol dehydrogenase-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51391,53613
51391 - Thiamin phosphate synthase
53613 - Ribokinase-like | 0 | Direct |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | Direct |
55608,56672
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | Direct |
53597,55831
53597 - Dihydrofolate reductase-like
55831 - Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
158472,47384
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
82549,101473
82549 - DAK1/DegV-like
101473 - DhaL-like | 0 | Direct |
53448,51182
53448 - Nucleotide-diphospho-sugar transferases
51182 - RmlC-like cupins | 0 | Direct |
88697,52374
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | Direct |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
46915,54211
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
88697,82199
88697 - PUA domain-like
82199 - SET domain | 0 | Direct |
53335,50249
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50249 - Nucleic acid-binding proteins | 0 | Direct |
53335,53383
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53383 - PLP-dependent transferases | 0 | Direct |
46785,82114
46785 - "Winged helix" DNA-binding domain
82114 - Riboflavin kinase-like | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
57667,54928
57667 - beta-beta-alpha zinc fingers
54928 - RNA-binding domain, RBD | 0 | Direct |
49562,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | Direct |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | Direct |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
47212,56112
47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
55785,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like | 0 | Direct |
47391,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47384,55874
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
103473,53335
103473 - MFS general substrate transporter
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
51735,52540
51735 - NAD(P)-binding Rossmann-fold domains
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
55781,47384
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
117839,56399
117839 - WWE domain
56399 - ADP-ribosylation | 0 | Direct |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
52540,47648
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
53850,54782
53850 - Periplasmic binding protein-like II
54782 - Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,103243
56112 - Protein kinase-like (PK-like)
103243 - KA1-like | 0 | Direct |
52540,57802
52540 - P-loop containing nucleoside triphosphate hydrolases
57802 - Rubredoxin-like | 0 | Direct |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
53155,46767
53155 - Methylated DNA-protein cysteine methyltransferase domain
46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
50465,52540
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54171,82199
54171 - DNA-binding domain
82199 - SET domain | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
57889,111331
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | Direct |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
50249,89550
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
69360,51445
69360 - Cell wall binding repeat
51445 - (Trans)glycosidases | 0 | Direct |
56037,53271
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | Direct |
55931,48034
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
55979,55979
55979 - DNA clamp
55979 - DNA clamp | 0 | Direct |
51621,52935
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | Direct |
52402,52821
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
63999,63862
63999 - Thiamin pyrophosphokinase, catalytic domain
63862 - Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
53448,52266
53448 - Nucleotide-diphospho-sugar transferases
52266 - SGNH hydrolase | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56235,53271
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53271 - PRTase-like | 0 | Direct |
53448,51161
53448 - Nucleotide-diphospho-sugar transferases
51161 - Trimeric LpxA-like enzymes | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
53335,53335
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
53448,53448
53448 - Nucleotide-diphospho-sugar transferases
53448 - Nucleotide-diphospho-sugar transferases | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
55785,47384
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0 | Direct |
57850,57933
57850 - RING/U-box
57933 - TAZ domain | 0 | Direct |
53790,53335
53790 - Tetrapyrrole methylase
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57850,48371
57850 - RING/U-box
48371 - ARM repeat | 0 | Direct |
63748,82199
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
55315,75217
55315 - L30e-like
75217 - alpha/beta knot | 0 | Direct |
53633,53720
53633 - Carbamate kinase-like
53720 - ALDH-like | 0 | Direct |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | Direct |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
55052,47384
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
55781,55785
55781 - GAF domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
52087,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat | 0 | Direct |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | Direct |
47226,55052
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA | 0 | Direct |
53448,69765
53448 - Nucleotide-diphospho-sugar transferases
69765 - IpsF-like | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,53271
52540 - P-loop containing nucleoside triphosphate hydrolases
53271 - PRTase-like | 0 | Direct |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
46785,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
56112,55681
56112 - Protein kinase-like (PK-like)
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
52935,52009
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | Direct |
75217,54593
75217 - alpha/beta knot
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
53271,53271
53271 - PRTase-like
53271 - PRTase-like | 0 | Direct |
51621,55804
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
55073,56112
55073 - Nucleotide cyclase
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | Direct |
53850,54913
53850 - Periplasmic binding protein-like II
54913 - GlnB-like | 0 | Direct |
56112,50998
56112 - Protein kinase-like (PK-like)
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
52540,75138
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
56672,55608
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | Direct |
47831,52009
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
52113,47802
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like | 0 | Direct |
47769,56399
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
64268,56112
64268 - PX domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51230,52777
51230 - Single hybrid motif
52777 - CoA-dependent acyltransferases | 0 | Direct |
53448,56784
53448 - Nucleotide-diphospho-sugar transferases
56784 - HAD-like | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
56112,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain | 0 | Direct |
88697,53335
88697 - PUA domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
81593,81891
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
57440,56112
57440 - Kringle-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47807,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | Direct |
54277,56112
54277 - CAD & PB1 domains
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
52540,55729
52540 - P-loop containing nucleoside triphosphate hydrolases
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
102114,55729
102114 - Radical SAM enzymes
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
52009,51621
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
53633,88697
53633 - Carbamate kinase-like
88697 - PUA domain-like | 0 | Direct |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
47802,81585
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | Direct |
56112,90257
56112 - Protein kinase-like (PK-like)
90257 - Myosin rod fragments | 0 | Direct |
55594,47831
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,54928
56112 - Protein kinase-like (PK-like)
54928 - RNA-binding domain, RBD | 0 | Direct |
89000,110921
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | Direct |
52374,82114
52374 - Nucleotidylyl transferase
82114 - Riboflavin kinase-like | 0 | Direct |
55088,48081
55088 - Methyl-coenzyme M reductase subunits
48081 - Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
55729,47370
55729 - Acyl-CoA N-acyltransferases (Nat)
47370 - Bromodomain | 0 | Direct |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
101288,101288
101288 - L27 domain
101288 - L27 domain | 0 | Direct |
46785,56112
46785 - "Winged helix" DNA-binding domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
52833,47384
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
53756,53756
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53756 - UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
47807,53098
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | Direct |
54277,57889
54277 - CAD & PB1 domains
57889 - Cysteine-rich domain | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51717,47644
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
102114,53383
102114 - Radical SAM enzymes
53383 - PLP-dependent transferases | 0 | Direct |
52172,52172
52172 - CheY-like
52172 - CheY-like | 0 | Direct |
51735,48256
51735 - NAD(P)-binding Rossmann-fold domains
48256 - Citrate synthase | 0 | Direct |
56112,54427
56112 - Protein kinase-like (PK-like)
54427 - NTF2-like | 0 | Direct |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
81891,109604
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
50044,53335
50044 - SH3-domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
56112,50985
56112 - Protein kinase-like (PK-like)
50985 - RCC1/BLIP-II | 0 | Direct |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | Direct |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
69593,56801
69593 - Glycerol-3-phosphate (1)-acyltransferase
56801 - Acetyl-CoA synthetase-like | 0 | Direct |
56042,53328
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | Direct |
53633,55729
53633 - Carbamate kinase-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
50729,69322
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
52540,81301
52540 - P-loop containing nucleoside triphosphate hydrolases
81301 - Nucleotidyltransferase | 0 | Direct |
103190,55785
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
56112,52540
56112 - Protein kinase-like (PK-like)
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55781,55874
55781 - GAF domain-like
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | Direct |
53850,55785
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
54160,53335
54160 - Chromo domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
56059,52009
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain | 0 | Direct |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | Direct |
56112,48452
56112 - Protein kinase-like (PK-like)
48452 - TPR-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52317,47648
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
55785,55890
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | Direct |
56112,50044
56112 - Protein kinase-like (PK-like)
50044 - SH3-domain | 0 | Direct |
55804,52794
55804 - Phoshotransferase/anion transport protein
52794 - PTS system IIB component-like | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
143724,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | Direct |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
50156,56112
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53335,81799
53335 - S-adenosyl-L-methionine-dependent methyltransferases
81799 - Putative methyltransferase TM0872, insert domain | 0 | Direct |
52113,142921
52113 - BRCT domain
142921 - WGR domain-like | 0 | Direct |
63520,52794
63520 - PTS-regulatory domain, PRD
52794 - PTS system IIB component-like | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
52794,52794
52794 - PTS system IIB component-like
52794 - PTS system IIB component-like | 0 | Direct |
52242,56507
52242 - Cobalamin (vitamin B12)-binding domain
56507 - Methionine synthase activation domain-like | 0 | Direct |
103190,47384
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
50800,51621
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
82199,81822
82199 - SET domain
81822 - RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
88798,50249
88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
50249 - Nucleic acid-binding proteins | 0 | Direct |
56112,47473
56112 - Protein kinase-like (PK-like)
47473 - EF-hand | 0 | Direct |
75615,53790
75615 - Siroheme synthase middle domains-like
53790 - Tetrapyrrole methylase | 0 | Direct |
51569,54909
51569 - Aldolase
54909 - Dimeric alpha+beta barrel | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
48403,82199
48403 - Ankyrin repeat
82199 - SET domain | 0 | Direct |
63882,53218
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins | 0 | Direct |
46785,53335
46785 - "Winged helix" DNA-binding domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
54791,50249
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
55666,46915
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
53271,51366
53271 - PRTase-like
51366 - Ribulose-phoshate binding barrel | 0 | Direct |
52317,56322
52317 - Class I glutamine amidotransferase-like
56322 - ADC synthase | 0 | Direct |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | Direct |
55021,55021
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
55729,46589
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm | 0 | Direct |
55116,55116
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
54160,55729
54160 - Chromo domain-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
51294,56672
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases | 0 | Direct |
81301,81593
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
49265,63825
49265 - Fibronectin type III
63825 - YWTD domain | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
89550,53098
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | Direct |
48013,53335
48013 - NusB-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
47644,52242
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain | 0 | Direct |
47757,53335
47757 - Chemotaxis receptor methyltransferase CheR, N-terminal domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
55116,101262
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
101262 - Methenyltetrahydrofolate cyclohydrolase-like | 0 | Direct |
55874,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | Direct |
55666,54791
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
82199,48452
82199 - SET domain
48452 - TPR-like | 0 | Direct |
57774,52540
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55604,51261
55604 - Glucose permease domain IIB
51261 - Duplicated hybrid motif | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
75217,75217
75217 - alpha/beta knot
75217 - alpha/beta knot | 0 | Direct |
56112,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | Direct |
52540,57716
52540 - P-loop containing nucleoside triphosphate hydrolases
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
52172,47226
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
52794,55804
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
63825,49265
63825 - YWTD domain
49265 - Fibronectin type III | 0 | Direct |
56519,56601
56519 - Penicillin binding protein dimerisation domain
56601 - beta-lactamase/transpeptidase-like | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
56235,53697
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53697 - SIS domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
143437,52402
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 0 | Direct |
81631,57756
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
51230,51230
51230 - Single hybrid motif
51230 - Single hybrid motif | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
75138,53659
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
53850,56112
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,52799
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
55021,51735
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 0 | Direct |
75217,109604
75217 - alpha/beta knot
109604 - HD-domain/PDEase-like | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
55112,55112
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | Direct |
51197,53335
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
81585,81301
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | Direct |
50486,51735
50486 - FMT C-terminal domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53901,55718
53901 - Thiolase-like
55718 - SCP-like | 0 | Direct |
109604,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | Direct |
51735,75615
51735 - NAD(P)-binding Rossmann-fold domains
75615 - Siroheme synthase middle domains-like | 0 | Direct |
53955,56601
53955 - Lysozyme-like
56601 - beta-lactamase/transpeptidase-like | 0 | Direct |
82185,82199
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82199 - SET domain | 0 | Direct |
52949,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,53335
50249 - Nucleic acid-binding proteins
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
46589,55729
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
81995,56112
81995 - beta-sandwich domain of Sec23/24
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | Direct |
158472,55785
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000000425 | Direct |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0.00000000001599 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.00000000001599 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.00000000003174 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0.0000000000383 | Direct |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0.000000006496 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.00000002662 | Direct |
81296,49452
81296 - E set domains
49452 - Starch-binding domain-like | 0.0000001308 | Direct |
51011,81296
51011 - Glycosyl hydrolase domain
81296 - E set domains | 0.0000001308 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.000000555 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.0000009672 | Direct |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.00000263 | Direct |
51206,56112
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000263 | Direct |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.000002828 | Direct |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.000006248 | Direct |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00001836 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.00003052 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0.00004837 | Direct |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0.00006281 | Direct |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.00006634 | Direct |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.0001117 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0002365 | Direct |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.001044 | Inherited |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.002297 | Inherited |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0.003403 | Inherited |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.004174 | Inherited |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.004174 | Inherited |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.004174 | Inherited |
51445,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat | 0.005583 | Inherited |
69360,69360
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0.005583 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.005691 | Inherited |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0.007693 | Inherited |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.009091 | Inherited |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.01001 | Inherited |
51246,55326
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0.01891 | Inherited |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.02083 | Inherited |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.02598 | Inherited |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0726 | Inherited |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.0726 | Inherited |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.07638 | Inherited |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.1419 | Inherited |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.1534 | Inherited |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.1534 | Inherited |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.3178 | Inherited |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0.3647 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.4337 | Inherited |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.6445 | Inherited |
47336,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.8261 | Inherited |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.8329 | Inherited |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | Inherited |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 1 | Inherited |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 1 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 1 | Inherited |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 1 | Inherited |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
53383,53383
53383 - PLP-dependent transferases
53383 - PLP-dependent transferases | 1 | Inherited |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 1 | Inherited |
52402,82829
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like | 1 | Inherited |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 1 | Inherited |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | Inherited |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 1 | Inherited |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | Inherited |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | Inherited |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
56042,55326
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 1 | Inherited |
82829,56037
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 1 | Inherited |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | Inherited |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 1 | Inherited |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 1 | Inherited |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 1 | Inherited |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 1 | Inherited |
55620,55620
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
57783,57783
57783 - Zinc beta-ribbon
57783 - Zinc beta-ribbon | 1 | Inherited |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | Inherited |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (Not in SPEO)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,101288,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain
101288 - L27 domain | 0 | DIRECT |
52087,46966,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
57889,57889,111331
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
55785,55890,55874
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
50692,47648,52418
50692 - ADC-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55729,46589,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0 | DIRECT |
56796,55205,52540
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
52058,52058,56112
52058 - L domain-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48403,47769,56399
48403 - Ankyrin repeat
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | DIRECT |
52058,57184,57184
52058 - L domain-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
158472,55785,47384
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
52949,52540,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52317,47648,52418
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
88723,47807,56672
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | DIRECT |
52047,52047,52058
52047 - RNI-like
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
53098,56672,51294
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
57850,57850,57933
57850 - RING/U-box
57850 - RING/U-box
57933 - TAZ domain | 0 | DIRECT |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
50800,51621,52935
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | DIRECT |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
53850,53850,55785
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52833,47384,55874
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
55979,55979,55979
55979 - DNA clamp
55979 - DNA clamp
55979 - DNA clamp | 0 | DIRECT |
101912,103575,81296
101912 - Sema domain
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
54211,55666,54791
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
47384,55874,52172
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | DIRECT |
55594,47831,52009
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | DIRECT |
51294,56672,55608
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | DIRECT |
103190,47384,55874
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
47031,50729,56112
47031 - Second domain of FERM
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53850,55785,47384
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
53328,50486,51735
53328 - Formyltransferase
50486 - FMT C-terminal domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
57903,57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
47226,55052,47384
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
51717,47644,52242
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain | 0 | DIRECT |
55874,52172,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
52172 - CheY-like | 0 | DIRECT |
55608,56672,51294
55608 - Homing endonucleases
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55326,56042,53328
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
53098,56672,90234
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
46785,57903,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
101288,101288,50156
101288 - L27 domain
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
47802,81585,81301
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
63882,53218,63867
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | DIRECT |
140356,143724,56024
140356 - PPK N-terminal domain-like
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50447,50465,52540
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81296,81296,51445
81296 - E set domains
81296 - E set domains
51445 - (Trans)glycosidases | 0 | DIRECT |
55781,55781,47384
55781 - GAF domain-like
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
52113,47802,81585
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | DIRECT |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
47831,52009,51621
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
52540,57774,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57716,57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | DIRECT |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
103190,158472,55785
103190 - Sensory domain-like
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
54928,51197,53335
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
56553,55257,47789
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
82282,51717,47644
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | DIRECT |
55116,55116,101262
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
101262 - Methenyltetrahydrofolate cyclohydrolase-like | 0 | DIRECT |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55620,55083,51717
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
52518,52467,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
47031,50729,55550
47031 - Second domain of FERM
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
52540,47648,52418
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
47384,55874,50341
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | DIRECT |
55666,54791,50249
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
55666,46915,54211
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55785,55785,47384
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
56112,52799,49562
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
88697,52374,52540
88697 - PUA domain-like
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
52113,142921,47587
52113 - BRCT domain
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
51230,51230,47005
51230 - Single hybrid motif
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53633,55021,55021
53633 - Carbamate kinase-like
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
51569,89000,110921
51569 - Aldolase
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
55874,52172,47226
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
55785,55781,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57774,52540,57774
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
53335,51905,54373
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
54593,53784,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51621,52935,52009
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
57889,49562,56112
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52047,52047,56112
52047 - RNI-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81301,81593,81891
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
52949,52540,56672
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
55620,55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
49265,56112,48726
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | DIRECT |
57889,50729,69322
57889 - Cysteine-rich domain
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | DIRECT |
56112,48726,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
55785,47384,55874
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
48439,49594,52075
48439 - Protein prenylyltransferase
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
52075 - Outer arm dynein light chain 1 | 0 | DIRECT |
143437,52402,52821
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
55931,48034,55931
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
55785,55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | DIRECT |
47391,52540,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47644,52242,56507
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain
56507 - Methionine synthase activation domain-like | 0 | DIRECT |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
63825,49265,63825
63825 - YWTD domain
49265 - Fibronectin type III
63825 - YWTD domain | 0 | DIRECT |
47807,53098,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
51735,75615,53790
51735 - NAD(P)-binding Rossmann-fold domains
75615 - Siroheme synthase middle domains-like
53790 - Tetrapyrrole methylase | 0 | DIRECT |
55052,47384,55874
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
54211,55666,46915
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
48034,55931,48034
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | DIRECT |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
103190,55785,55890
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | DIRECT |
55781,47384,55874
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
81301,81631,57756
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
52009,51621,55804
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
81891,109604,55021
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | DIRECT |
52058,52047,56112
52058 - L domain-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
81296,51445,51011
81296 - E set domains
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
51445,69360,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0 | DIRECT |
47648,52418,54680
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
63520,52794,55804
63520 - PTS-regulatory domain, PRD
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
53335,53383,53383
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53383 - PLP-dependent transferases
53383 - PLP-dependent transferases | 0 | DIRECT |
143724,56024,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
56112,48403,52540
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
55021,55021,51735
55021 - ACT-like
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
51735,50129,51735
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,88697,52374
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
48726,48726,56112
48726 - Immunoglobulin
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
52058,52047,52058
52058 - L domain-like
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
63520,63520,52794
63520 - PTS-regulatory domain, PRD
63520 - PTS-regulatory domain, PRD
52794 - PTS system IIB component-like | 0 | DIRECT |
50249,89550,53098
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
48403,48403,47769
48403 - Ankyrin repeat
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | DIRECT |
53901,53901,55718
53901 - Thiolase-like
53901 - Thiolase-like
55718 - SCP-like | 0 | DIRECT |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
52047,52058,56112
52047 - RNI-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
109604,55021,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
88723,47807,53098
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | DIRECT |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
52540,75138,53659
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
50729,50044,55550
50729 - PH domain-like
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
48097,56112,50729
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
53850,53850,56112
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
52210,51735,48256
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains
48256 - Citrate synthase | 0 | DIRECT |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
82829,56037,53271
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
56059,52210,51735
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
56059,52009,51621
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
56672,55608,56672
56672 - DNA/RNA polymerases
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | DIRECT |
158472,47384,55874
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
46915,54211,55666
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
56112,116846,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain
116846 - MIT domain | 0 | DIRECT |
57716,50156,56112
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
55021,51735,55347
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
51011,81296,49452
51011 - Glycosyl hydrolase domain
81296 - E set domains
49452 - Starch-binding domain-like | 0.0000001308 | DIRECT |
51445,51011,81296
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
81296 - E set domains | 0.0000001308 | DIRECT |
51206,51206,56112
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000263 | DIRECT |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00001836 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.0001424 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0005001 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0.002837 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorous-containing groups |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.004174 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0.007693 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorous-containing groups |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.009091 | INHERITED FROM: Transferring one-carbon groups || Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.009091 | INHERITED FROM: Transferring one-carbon groups || Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
51246,55326,56042
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0.01891 | INHERITED FROM: Transferring one-carbon groups || Phosphoribosylglycinamide formyltransferase || Hydroxymethyl-, formyl- and related transferases |
56059,51246,55326
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0.01891 | INHERITED FROM: Transferring one-carbon groups || Phosphoribosylglycinamide formyltransferase || Hydroxymethyl-, formyl- and related transferases |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.3178 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.4769 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
47336,52777,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.8261 | INHERITED FROM: Acyltransferases || Transferring groups other than amino-acyl groups |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
52402,82829,56037
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
55326,56042,55326
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
56042,55326,56042
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: Carboxyl- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,101288,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain
101288 - L27 domain | 0 | Direct |
52087,46966,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
57889,57889,111331
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | Direct |
55785,55890,55874
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
50692,47648,52418
50692 - ADC-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
55729,46589,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0 | Direct |
56796,55205,52540
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
52058,52058,56112
52058 - L domain-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48403,47769,56399
48403 - Ankyrin repeat
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | Direct |
52058,57184,57184
52058 - L domain-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
158472,55785,47384
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
52949,52540,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52317,47648,52418
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
88723,47807,56672
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | Direct |
52047,52047,52058
52047 - RNI-like
52047 - RNI-like
52058 - L domain-like | 0 | Direct |
53098,56672,51294
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
57850,57850,57933
57850 - RING/U-box
57850 - RING/U-box
57933 - TAZ domain | 0 | Direct |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
50800,51621,52935
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | Direct |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
53850,53850,55785
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52833,47384,55874
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
55979,55979,55979
55979 - DNA clamp
55979 - DNA clamp
55979 - DNA clamp | 0 | Direct |
101912,103575,81296
101912 - Sema domain
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
54211,55666,54791
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
47384,55874,52172
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | Direct |
55594,47831,52009
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | Direct |
51294,56672,55608
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | Direct |
103190,47384,55874
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
47031,50729,56112
47031 - Second domain of FERM
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53850,55785,47384
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
53328,50486,51735
53328 - Formyltransferase
50486 - FMT C-terminal domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
57903,57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
47226,55052,47384
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
51717,47644,52242
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain | 0 | Direct |
55874,52172,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
52172 - CheY-like | 0 | Direct |
55608,56672,51294
55608 - Homing endonucleases
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
55326,56042,53328
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
53098,56672,90234
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
46785,57903,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
101288,101288,50156
101288 - L27 domain
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
47802,81585,81301
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | Direct |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
63882,53218,63867
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | Direct |
140356,143724,56024
140356 - PPK N-terminal domain-like
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | Direct |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50447,50465,52540
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81296,81296,51445
81296 - E set domains
81296 - E set domains
51445 - (Trans)glycosidases | 0 | Direct |
55781,55781,47384
55781 - GAF domain-like
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
52113,47802,81585
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | Direct |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
47831,52009,51621
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
52540,57774,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57716,57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | Direct |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | Direct |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
103190,158472,55785
103190 - Sensory domain-like
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
54928,51197,53335
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
56553,55257,47789
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
82282,51717,47644
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | Direct |
55116,55116,101262
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
101262 - Methenyltetrahydrofolate cyclohydrolase-like | 0 | Direct |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55620,55083,51717
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | Direct |
52518,52467,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
47031,50729,55550
47031 - Second domain of FERM
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
52540,47648,52418
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
47384,55874,50341
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | Direct |
55666,54791,50249
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | Direct |
55666,46915,54211
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55785,55785,47384
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
56112,52799,49562
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
88697,52374,52540
88697 - PUA domain-like
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
52113,142921,47587
52113 - BRCT domain
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
51230,51230,47005
51230 - Single hybrid motif
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53633,55021,55021
53633 - Carbamate kinase-like
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
51569,89000,110921
51569 - Aldolase
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
55874,52172,47226
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
55785,55781,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
57774,52540,57774
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
53335,51905,54373
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
54593,53784,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51621,52935,52009
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | Direct |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
57889,49562,56112
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
52047,52047,56112
52047 - RNI-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81301,81593,81891
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
52949,52540,56672
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
55620,55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
49265,56112,48726
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | Direct |
57889,50729,69322
57889 - Cysteine-rich domain
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | Direct |
56112,48726,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
55785,47384,55874
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
48439,49594,52075
48439 - Protein prenylyltransferase
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
52075 - Outer arm dynein light chain 1 | 0 | Direct |
143437,52402,52821
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
55931,48034,55931
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
55785,55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57903,63748,82199
57903 - FYVE/PHD zinc finger
63748 - Tudor/PWWP/MBT
82199 - SET domain | 0 | Direct |
47391,52540,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47644,52242,56507
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain
56507 - Methionine synthase activation domain-like | 0 | Direct |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
63825,49265,63825
63825 - YWTD domain
49265 - Fibronectin type III
63825 - YWTD domain | 0 | Direct |
47807,53098,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
51735,75615,53790
51735 - NAD(P)-binding Rossmann-fold domains
75615 - Siroheme synthase middle domains-like
53790 - Tetrapyrrole methylase | 0 | Direct |
55052,47384,55874
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
54211,55666,46915
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
48034,55931,48034
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | Direct |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
103190,55785,55890
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | Direct |
55781,47384,55874
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
81301,81631,57756
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
63748,82199,57903
63748 - Tudor/PWWP/MBT
82199 - SET domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
52009,51621,55804
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
81891,109604,55021
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | Direct |
52058,52047,56112
52058 - L domain-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
81296,51445,51011
81296 - E set domains
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
51445,69360,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0 | Direct |
47648,52418,54680
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
63520,52794,55804
63520 - PTS-regulatory domain, PRD
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
53335,53383,53383
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53383 - PLP-dependent transferases
53383 - PLP-dependent transferases | 0 | Direct |
143724,56024,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
56112,48403,52540
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
55021,55021,51735
55021 - ACT-like
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
51735,50129,51735
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,88697,52374
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | Direct |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
48726,48726,56112
48726 - Immunoglobulin
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
52058,52047,52058
52058 - L domain-like
52047 - RNI-like
52058 - L domain-like | 0 | Direct |
63520,63520,52794
63520 - PTS-regulatory domain, PRD
63520 - PTS-regulatory domain, PRD
52794 - PTS system IIB component-like | 0 | Direct |
50249,89550,53098
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | Direct |
48403,48403,47769
48403 - Ankyrin repeat
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | Direct |
53901,53901,55718
53901 - Thiolase-like
53901 - Thiolase-like
55718 - SCP-like | 0 | Direct |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
52047,52058,56112
52047 - RNI-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
109604,55021,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
88723,47807,53098
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | Direct |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
52540,75138,53659
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
50729,50044,55550
50729 - PH domain-like
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
48097,56112,50729
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
53850,53850,56112
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
52210,51735,48256
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains
48256 - Citrate synthase | 0 | Direct |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
82829,56037,53271
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
56059,52210,51735
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
56059,52009,51621
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
56672,55608,56672
56672 - DNA/RNA polymerases
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | Direct |
158472,47384,55874
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
46915,54211,55666
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
56112,116846,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain
116846 - MIT domain | 0 | Direct |
57716,50156,56112
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
55021,51735,55347
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
51011,81296,49452
51011 - Glycosyl hydrolase domain
81296 - E set domains
49452 - Starch-binding domain-like | 0.0000001308 | Direct |
51445,51011,81296
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
81296 - E set domains | 0.0000001308 | Direct |
51206,51206,56112
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000263 | Direct |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00001836 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.0001424 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0005001 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0.002837 | Inherited |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.004174 | Inherited |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.004174 | Inherited |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0.007693 | Inherited |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.009091 | Inherited |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.009091 | Inherited |
51246,55326,56042
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0.01891 | Inherited |
56059,51246,55326
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0.01891 | Inherited |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.3178 | Inherited |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.4769 | Inherited |
47336,52777,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.8261 | Inherited |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | Inherited |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
52402,82829,56037
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 1 | Inherited |
55326,56042,55326
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 1 | Inherited |
56042,55326,56042
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 1 | Inherited |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 1 | Inherited |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | Inherited |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
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heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
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