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Hydrolases
(show info)
Enzyme Commission (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed. To navigate hierarchical structure of EC, we display all parental EC terms to the current EC term of interest ordered by their shortest distances to the current term. Also, only direct children EC terms of the current EC term are listed.
Structural Classification of Proteins (SCOP)
SCOP classifies evolutionary-related domains into Superfamily level and Family level. Accordingly, we have generated the domain-centric EC annotations for each of the three concepts at each of the two domain levels.
Structural Domain Enzyme Commission Ontology (SDEO)
As domain-centric ontology, SDEO only refers to those EC terms which are the most informative to annotate SCOP domains.
EC annotations for SCOP domains
For details, please visit Documentation: EC annotations for SCOP domains. Therein, we provide several relevant files ( Data Availability) for the download, including an annotation file (i.e., Domain2EC.txt) and the corresponding ontology (i.e., SDEO.txt).
Supra-domain Enzyme Commission Ontology (SPEO)
As an extension, SPEO includes those EC terms which are the most informative to annotate supra-domains and individual SCOP domains at the Superfamily level.
EC annotations for Supra-domains
For details, please visit Documentation: EC annotations for Supra-domains. Therein, we provide several relevant files ( Data Availability) for the download, including a annotation file (i.e., SP2EC.txt) and an ontology (i.e., SPEO.txt). For the sake of being browsable, listed below are those supra-domains (single, dual, triple, quad).
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (Not in SDEO)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| tRNA-intron endonuclease N-terminal domain-like | 0 | DIRECT |
| Cellulose-binding domain | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| (Trans)glycosidases | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Anthrax protective antigen | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Methylesterase CheB, C-terminal domain | 0 | DIRECT |
| TRAF domain-like | 0 | DIRECT |
| STI-like | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Toprim domain | 0 | DIRECT |
| beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| SRCR-like | 0 | DIRECT |
| Phospholipase C/P1 nuclease | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Cellulose docking domain, dockering | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| XseB-like | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| Outer membrane phospholipase A (OMPLA) | 0 | DIRECT |
| (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
| Coronavirus NSP8-like | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| RNase A-like | 0 | DIRECT |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | DIRECT |
| Carbohydrate-binding domain | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| Plant lectins/antimicrobial peptides | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| Galactose-binding domain-like | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Prokaryotic SH3-related domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Coronavirus NSP7-like | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Rof/RNase P subunit-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| HybD-like | 0 | DIRECT |
| Putative isomerase YbhE | 0 | DIRECT |
| Type I dockerin domain | 0 | DIRECT |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| Holliday junction resolvase RusA | 0 | DIRECT |
| all-alpha NTP pyrophosphatases | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| Rnp2-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Saposin | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| Origin of replication-binding domain, RBD-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Ribosome inactivating proteins (RIP) | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Phosphotyrosine protein phosphatases I | 0 | DIRECT |
| Cysteine proteinases | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Nitrous oxide reductase, N-terminal domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| EGF/Laminin | 0 | DIRECT |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| Aminopeptidase/glucanase lid domain | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Peptidyl-tRNA hydrolase domain-like | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| Penicillin-binding protein associated domain | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| alpha/beta-Hydrolases | 0 | DIRECT |
| Herpes virus serine proteinase, assemblin | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| beta-N-acetylhexosaminidase-like domain | 0 | DIRECT |
| Carbohydrate binding domain | 0 | DIRECT |
| Peptidyl-tRNA hydrolase-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Ribonuclease Rh-like | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| DHH phosphoesterases | 0 | DIRECT |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Glycosyl hydrolases family 6, cellulases | 0 | DIRECT |
| Nucleoside hydrolase | 0 | DIRECT |
| Peptidyl-tRNA hydrolase II | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| MOP-like | 0 | DIRECT |
| L9 N-domain-like | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Viral protein domain | 0 | DIRECT |
| SurE-like | 0 | DIRECT |
| TMV-like viral coat proteins | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Phage fibre proteins | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| ComB-like | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| Microbial ribonucleases | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| Replicase NSP9 | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| AbfB domain | 0 | DIRECT |
| Influenza hemagglutinin (stalk) | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | DIRECT |
| Acylphosphatase/BLUF domain-like | 0 | DIRECT |
| Arabinanase/levansucrase/invertase | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| SARS Nsp1-like | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| Thermostable phytase (3-phytase) | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| Autotransporter | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Coronavirus NSP10-like | 0 | DIRECT |
| NSP3A-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| EF-hand | 2.368e-16 | DIRECT |
| LysM domain | 0.00000000000000646 | DIRECT |
| Xylose isomerase-like | 0.00000000000004583 | DIRECT |
| Calcium-dependent phosphotriesterase | 0.0000000000002436 | DIRECT |
| RING/U-box | 0.000000000001346 | DIRECT |
| Sec63 N-terminal domain-like | 0.000000000002663 | DIRECT |
| HIT-like | 0.000000000007869 | DIRECT |
| Ubiquitin-like | 0.0000000000572 | DIRECT |
| Purine and uridine phosphorylases | 0.000000001607 | DIRECT |
| GAF domain-like | 0.000000002921 | DIRECT |
| beta-Roll | 0.000000002927 | DIRECT |
| PH domain-like | 0.00000000565 | DIRECT |
| Translation proteins | 0.00000003355 | DIRECT |
| CYTH-like phosphatases | 0.00000008736 | DIRECT |
| UBA-like | 0.0000001325 | DIRECT |
| Hairpin loop containing domain-like | 0.0000002137 | DIRECT |
| LDL receptor-like module | 0.0000002137 | DIRECT |
| HD-domain/PDEase-like | 0.0000006673 | DIRECT |
| DEATH domain | 0.0000009953 | DIRECT |
| YrdC/RibB | 0.000001143 | DIRECT |
| Fibronectin type III | 0.000001511 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.000004397 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0.000004476 | DIRECT |
| Starch-binding domain-like | 0.00000592 | DIRECT |
| Phospholipase D/nuclease | 0.000006932 | DIRECT |
| Staphylococcal nuclease | 0.00001471 | DIRECT |
| SAP domain | 0.00001634 | DIRECT |
| CBD9-like | 0.00003747 | DIRECT |
| EAL domain-like | 0.00003747 | DIRECT |
| HCP-like | 0.00005745 | DIRECT |
| DEK C-terminal domain | 0.00005892 | DIRECT |
| HIT/MYND zinc finger-like | 0.00006311 | DIRECT |
| WD40 repeat-like | 0.00009273 | DIRECT |
| Phosphoglycerate mutase-like | 0.0001495 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0.0002488 | DIRECT |
| FnI-like domain | 0.0005077 | DIRECT |
| Ran binding protein zinc finger-like | 0.0005077 | DIRECT |
| Tudor/PWWP/MBT | 0.0006541 | DIRECT |
| Barwin-like endoglucanases | 0.0006683 | DIRECT |
| Integrin alpha N-terminal domain | 0.002891 | INHERITED FROM: Glycosylphosphatidylinositol phospholipase D || Acting on ester bonds || Phosphoric diester hydrolases |
| Ankyrin repeat | 0.006521 | INHERITED FROM: Carboxylic ester hydrolases || Glutaminase || NAD(+) diphosphatase || In linear amides || Acting on carbon-nitrogen bonds, other than peptid |
| Hedgehog/intein (Hint) domain | 0.007242 | INHERITED FROM: H(+)-transporting two-sector ATPase || DNA helicase || Acting on acid anhydrides |
| Ricin B-like lectins | 0.01283 | INHERITED FROM: Alpha-galactosidase || Glycosylases || rRNA N-glycosylase |
| Homing endonucleases | 0.01488 | INHERITED FROM: H(+)-transporting two-sector ATPase || DNA helicase || Acting on acid anhydrides |
| Second domain of FERM | 0.01793 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Chromo domain-like | 0.02041 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase || Acting on acid anhydrides |
| PX domain | 0.0229 | INHERITED FROM: Phospholipase D || Acting on ester bonds || Phosphoric diester hydrolases |
| RNA-binding domain, RBD | 0.02942 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase || Exoribonucleases producing 5'-phosphomonoesters || Phosphoinositide 5-phosphatase || Poly(A)-specific ribonuclease |
| E set domains | 0.03195 | INHERITED FROM: Flavivirin || Nucleoside-triphosphatase || Acting on peptide bonds (peptide hydrolases) || Glycosylases || Acting on acid anhydrides; involved in cellular an || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || RNA helicase || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehal || In phosphorous-containing anhydrides || Acting on acid anhydrides || Pullulanase || Togavirin || Serine endopeptidases || Isoamylase |
| MIT domain | 0.05561 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Microtubule-severing ATPase || Acting on acid anhydrides |
| Thioesterase/thiol ester dehydrase-isomerase | 0.05832 | INHERITED FROM: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase || Acting on ester bonds || Thiolester hydrolases |
| Rhodanese/Cell cycle control phosphatase | 0.1113 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase || Omega peptidases || Phosphoprotein phosphatase || Ubiquitinyl hydrolase 1 |
| FAH | 0.2127 | INHERITED FROM: Acting on carbon-carbon bonds || Fumarylacetoacetase || Acylpyruvate hydrolase |
| NTF2-like | 0.3003 | INHERITED FROM: Phosphoric monoester hydrolases || Sucrose-phosphate phosphatase || Acting on ester bonds |
| ARM repeat | 0.3047 | INHERITED FROM: Ether hydrolases || Leukotriene-A(4) hydrolase || Omega peptidases || Acting on ether bonds || Ubiquitinyl hydrolase 1 |
| Duplicated hybrid motif | 0.4533 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Metalloendopeptidases || Lysostaphin |
| PHP domain-like | 0.4736 | INHERITED FROM: Ribonuclease P || Acting on ester bonds || Histidinol-phosphatase || Endoribonucleases producing 5'-phosphomonoesters |
| WW domain | 0.6748 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
| FYVE/PHD zinc finger | 0.6913 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on acid anhydrides; involved in cellular an || DNA helicase || Protein-tyrosine-phosphatase |
| Kelch motif | 0.8239 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoprotein phosphatase |
| Prokaryotic type I DNA topoisomerase | 0.91 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase || Acting on acid anhydrides |
| SH3-domain | 1 | INHERITED FROM: Phosphoinositide phospholipase C || Phosphoric diester hydrolases |
| Immunoglobulin | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Cupredoxins | 1 | INHERITED FROM: Protein-arginine deiminase || In linear amidines |
| DHS-like NAD/FAD-binding domain | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| DNA-glycosylase | 1 | INHERITED FROM: DNA-3-methyladenine glycosylase II || Glycosylases || Hydrolyzing N-glycosyl compounds |
| Heme oxygenase-like | 1 | INHERITED FROM: Aminopyrimidine aminohydrolase || In other compounds |
| TPR-like | 1 | INHERITED FROM: Phosphoprotein phosphatase |
| SAM/Pointed domain | 1 | INHERITED FROM: Phosphatidylinositol-3,4,5-trisphosphate 5-phospha |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Flavivirin || Nucleoside-triphosphatase || RNA helicase || Polynucleotide 5'-phosphatase || SARS coronavirus main proteinase || Oleoyl-[acyl-carrier-protein] hydrolase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Dipeptidases || Dipeptidase E || Cyanophycinase || Gamma-glutamyl hydrolase || Beta-galactosidase || Peptidyl-dipeptidases |
| DNA clamp | 1 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoeste || Exodeoxyribonuclease III |
| SH2 domain | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoinositide phospholipase C || Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric diester hydrolases || Phosphatidylinositol-3,4,5-trisphosphate 5-phospha |
| Carbonic anhydrase | 1 | INHERITED FROM: Protein-tyrosine-phosphatase |
| AraD/HMP-PK domain-like | 1 | INHERITED FROM: Acireductone synthase |
| ACP-like | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| RmlC-like cupins | 1 | INHERITED FROM: In linear amidines || Ureidoglycolate hydrolase || Acting on carbon-nitrogen bonds, other than peptid |
| Ribosomal protein S5 domain 2-like | 1 | INHERITED FROM: Ribonuclease P || Acting on ester bonds || Histidinol-phosphatase || Endopeptidase La || Serine endopeptidases || Endoribonucleases producing 5'-phosphomonoesters |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Alkaline phosphatase || Phosphodiesterase I || Nucleotide diphosphatase || Sulfuric ester hydrolases || Acting on ester bonds || Phosphoric diester hydrolases |
| GroES-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: 1-aminocyclopropane-1-carboxylate deaminase || In other compounds || Acting on carbon-nitrogen bonds, other than peptid |
| PUA domain-like | 1 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Endopeptidase La || Serine endopeptidases |
| Growth factor receptor domain | 1 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Furin || Serine endopeptidases |
| Thiolase-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Actin-like ATPase domain | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha || Exopolyphosphatase |
| FMT C-terminal domain-like | 1 | INHERITED FROM: DNA-3-methyladenine glycosylase II |
| LuxS/MPP-like metallohydrolase | 1 | INHERITED FROM: Mitochondrial processing peptidase || Acting on peptide bonds (peptide hydrolases) || Metalloendopeptidases || Insulysin || Pitrilysin |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: Polynucleotide 5'-phosphatase |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA helicase |
| ADC-like | 1 | INHERITED FROM: Vesicle-fusing ATPase |
| ACT-like | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Formyltetrahydrofolate deformylase || Diphosphoric monoester hydrolases |
| TGS-like | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases |
| Nucleotidyltransferase | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Exoribonucleases producing 5'-phosphomonoesters || Ribonuclease E || DNA helicase || Acting on acid anhydrides || Exoribonuclease II |
| LDH C-terminal domain-like | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase || In cyclic amidines || Methenyltetrahydrofolate cyclohydrolase || Thioether and trialkylsulfonium hydrolases || Acting on carbon-nitrogen bonds, other than peptid || Acting on ether bonds || Oleoyl-[acyl-carrier-protein] hydrolase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| PLP-dependent transferases | 1 | INHERITED FROM: Acting on carbon-carbon bonds || Kynureninase |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Diaminohydroxyphosphoribosylaminopyrimidine deamin || In cyclic amidines || Acting on carbon-nitrogen bonds, other than peptid |
| L domain-like | 1 | INHERITED FROM: Exoribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Phosphoprotein phosphatase || Poly(A)-specific ribonuclease |
| PYP-like sensor domain (PAS domain) | 1 | INHERITED FROM: 3',5'-cyclic-nucleotide phosphodiesterase || Phosphoric diester hydrolases |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| tRNA-intron endonuclease N-terminal domain-like | 0 | Direct |
| Cellulose-binding domain | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Putative cyclase | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| (Trans)glycosidases | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| AlbA-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Anthrax protective antigen | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Methylesterase CheB, C-terminal domain | 0 | Direct |
| TRAF domain-like | 0 | Direct |
| STI-like | 0 | Direct |
| GLA-domain | 0 | Direct |
| LigT-like | 0 | Direct |
| PA domain | 0 | Direct |
| Toprim domain | 0 | Direct |
| beta-Galactosidase/glucuronidase domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| SRCR-like | 0 | Direct |
| Phospholipase C/P1 nuclease | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Cellulose docking domain, dockering | 0 | Direct |
| LmbE-like | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| Kringle-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| XseB-like | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| HisI-like | 0 | Direct |
| PKD domain | 0 | Direct |
| Macro domain-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Sialidases | 0 | Direct |
| Acid proteases | 0 | Direct |
| CheY-like | 0 | Direct |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| Outer membrane phospholipase A (OMPLA) | 0 | Direct |
| (Phosphotyrosine protein) phosphatases II | 0 | Direct |
| Coronavirus NSP8-like | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| RNase A-like | 0 | Direct |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | Direct |
| Carbohydrate-binding domain | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| Plant lectins/antimicrobial peptides | 0 | Direct |
| Caspase-like | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| Galactose-binding domain-like | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| Plant invertase/pectin methylesterase inhibitor | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Prokaryotic SH3-related domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Coronavirus NSP7-like | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Rof/RNase P subunit-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| HybD-like | 0 | Direct |
| Putative isomerase YbhE | 0 | Direct |
| Type I dockerin domain | 0 | Direct |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| Holliday junction resolvase RusA | 0 | Direct |
| all-alpha NTP pyrophosphatases | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| Rnp2-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Saposin | 0 | Direct |
| DNase I-like | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| EndoU-like | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| HAD-like | 0 | Direct |
| PUG domain-like | 0 | Direct |
| Origin of replication-binding domain, RBD-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| PGBD-like | 0 | Direct |
| Ribosome inactivating proteins (RIP) | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Phosphotyrosine protein phosphatases I | 0 | Direct |
| Cysteine proteinases | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Beta-galactosidase LacA, domain 3 | 0 | Direct |
| RibA-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Nitrous oxide reductase, N-terminal domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| EGF/Laminin | 0 | Direct |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| Aminopeptidase/glucanase lid domain | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
| Trefoil | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| HRDC-like | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Peptidyl-tRNA hydrolase domain-like | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| Penicillin-binding protein associated domain | 0 | Direct |
| vWA-like | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| alpha/beta-Hydrolases | 0 | Direct |
| Herpes virus serine proteinase, assemblin | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| beta-N-acetylhexosaminidase-like domain | 0 | Direct |
| Carbohydrate binding domain | 0 | Direct |
| Peptidyl-tRNA hydrolase-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Ribonuclease Rh-like | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| DHH phosphoesterases | 0 | Direct |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Glycosyl hydrolases family 6, cellulases | 0 | Direct |
| Nucleoside hydrolase | 0 | Direct |
| Peptidyl-tRNA hydrolase II | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| MOP-like | 0 | Direct |
| L9 N-domain-like | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Viral protein domain | 0 | Direct |
| SurE-like | 0 | Direct |
| TMV-like viral coat proteins | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Phage fibre proteins | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| ComB-like | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| SEA domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| Nudix | 0 | Direct |
| DUSP-like | 0 | Direct |
| PP2C-like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| dUTPase-like | 0 | Direct |
| Microbial ribonucleases | 0 | Direct |
| Creatininase | 0 | Direct |
| Replicase NSP9 | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| ITPase-like | 0 | Direct |
| AbfB domain | 0 | Direct |
| Influenza hemagglutinin (stalk) | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | Direct |
| Acylphosphatase/BLUF domain-like | 0 | Direct |
| Arabinanase/levansucrase/invertase | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Pentein | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| SARS Nsp1-like | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| Thermostable phytase (3-phytase) | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| Autotransporter | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Coronavirus NSP10-like | 0 | Direct |
| NSP3A-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| EF-hand | 2.368e-16 | Direct |
| LysM domain | 0.00000000000000646 | Direct |
| Xylose isomerase-like | 0.00000000000004583 | Direct |
| Calcium-dependent phosphotriesterase | 0.0000000000002436 | Direct |
| RING/U-box | 0.000000000001346 | Direct |
| Sec63 N-terminal domain-like | 0.000000000002663 | Direct |
| HIT-like | 0.000000000007869 | Direct |
| Ubiquitin-like | 0.0000000000572 | Direct |
| Purine and uridine phosphorylases | 0.000000001607 | Direct |
| GAF domain-like | 0.000000002921 | Direct |
| beta-Roll | 0.000000002927 | Direct |
| PH domain-like | 0.00000000565 | Direct |
| Translation proteins | 0.00000003355 | Direct |
| CYTH-like phosphatases | 0.00000008736 | Direct |
| UBA-like | 0.0000001325 | Direct |
| Hairpin loop containing domain-like | 0.0000002137 | Direct |
| LDL receptor-like module | 0.0000002137 | Direct |
| HD-domain/PDEase-like | 0.0000006673 | Direct |
| DEATH domain | 0.0000009953 | Direct |
| YrdC/RibB | 0.000001143 | Direct |
| Fibronectin type III | 0.000001511 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.000004397 | Direct |
| N-(deoxy)ribosyltransferase-like | 0.000004476 | Direct |
| Starch-binding domain-like | 0.00000592 | Direct |
| Phospholipase D/nuclease | 0.000006932 | Direct |
| Staphylococcal nuclease | 0.00001471 | Direct |
| SAP domain | 0.00001634 | Direct |
| CBD9-like | 0.00003747 | Direct |
| EAL domain-like | 0.00003747 | Direct |
| HCP-like | 0.00005745 | Direct |
| DEK C-terminal domain | 0.00005892 | Direct |
| HIT/MYND zinc finger-like | 0.00006311 | Direct |
| WD40 repeat-like | 0.00009273 | Direct |
| Phosphoglycerate mutase-like | 0.0001495 | Direct |
| NagB/RpiA/CoA transferase-like | 0.0002488 | Direct |
| FnI-like domain | 0.0005077 | Direct |
| Ran binding protein zinc finger-like | 0.0005077 | Direct |
| Tudor/PWWP/MBT | 0.0006541 | Direct |
| Barwin-like endoglucanases | 0.0006683 | Direct |
| Integrin alpha N-terminal domain | 0.002891 | Inherited |
| Ankyrin repeat | 0.006521 | Inherited |
| Hedgehog/intein (Hint) domain | 0.007242 | Inherited |
| Ricin B-like lectins | 0.01283 | Inherited |
| Homing endonucleases | 0.01488 | Inherited |
| Second domain of FERM | 0.01793 | Inherited |
| Chromo domain-like | 0.02041 | Inherited |
| PX domain | 0.0229 | Inherited |
| RNA-binding domain, RBD | 0.02942 | Inherited |
| E set domains | 0.03195 | Inherited |
| MIT domain | 0.05561 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 0.05832 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.1113 | Inherited |
| FAH | 0.2127 | Inherited |
| NTF2-like | 0.3003 | Inherited |
| ARM repeat | 0.3047 | Inherited |
| Duplicated hybrid motif | 0.4533 | Inherited |
| PHP domain-like | 0.4736 | Inherited |
| WW domain | 0.6748 | Inherited |
| FYVE/PHD zinc finger | 0.6913 | Inherited |
| Kelch motif | 0.8239 | Inherited |
| Prokaryotic type I DNA topoisomerase | 0.91 | Inherited |
| SH3-domain | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| Cupredoxins | 1 | Inherited |
| DHS-like NAD/FAD-binding domain | 1 | Inherited |
| DNA-glycosylase | 1 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| TPR-like | 1 | Inherited |
| SAM/Pointed domain | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| Class I glutamine amidotransferase-like | 1 | Inherited |
| DNA clamp | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| Carbonic anhydrase | 1 | Inherited |
| AraD/HMP-PK domain-like | 1 | Inherited |
| ACP-like | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| Ribosomal protein S5 domain 2-like | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| GroES-like | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| PUA domain-like | 1 | Inherited |
| Growth factor receptor domain | 1 | Inherited |
| Thiolase-like | 1 | Inherited |
| Actin-like ATPase domain | 1 | Inherited |
| FMT C-terminal domain-like | 1 | Inherited |
| LuxS/MPP-like metallohydrolase | 1 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| ADC-like | 1 | Inherited |
| ACT-like | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Nucleotidyltransferase | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| LDH C-terminal domain-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| PLP-dependent transferases | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| L domain-like | 1 | Inherited |
| PYP-like sensor domain (PAS domain) | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
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Family(show details)
Family domains annotated to this (Not in SDEO)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Mammalian PLC | 0 | DIRECT |
| Coronavirus NSP8-like | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Peptidoglycan binding domain, PGBD | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| RuvC resolvase | 0 | DIRECT |
| Nsp15 C-terminal domain-like | 0 | DIRECT |
| Manganese-dependent inorganic pyrophosphatase (family II) | 0 | DIRECT |
| Plant cytotoxins | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Fibronectin type II module | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Pyrimidine 5'-nucleotidase (UMPH-1) | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| Type 2 phosphatidic acid phosphatase, PAP2 | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| Thioesterases | 0 | DIRECT |
| Class II viral fusion proteins C-terminal domain | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0 | DIRECT |
| Leucine aminopeptidase (Aminopeptidase A), N-terminal domain | 0 | DIRECT |
| TMV-like viral coat proteins | 0 | DIRECT |
| Glycosyl hydrolases family 32 N-terminal domain | 0 | DIRECT |
| NADH pyrophosphatase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Beta-galactosidase LacA, domain 2 | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| GlpX-like bacterial fructose-1,6-bisphosphatase | 0 | DIRECT |
| Pancreatic lipase, N-terminal domain | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| HtrA-like serine proteases | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| alpha-subunit of urease, catalytic domain | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Subtilase propeptides/inhibitors | 0 | DIRECT |
| G-type lysozyme | 0 | DIRECT |
| Phosphoserine phosphatase | 0 | DIRECT |
| Pectin methylesterase | 0 | DIRECT |
| DNA helicase RuvA subunit, N-terminal domain | 0 | DIRECT |
| Serralysin-like metalloprotease, catalytic (N-terminal) domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
| alpha-D-glucuronidase, N-terminal domain | 0 | DIRECT |
| Proline iminopeptidase-like | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| Herpes virus serine proteinase, assemblin | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| VanX-like | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| 3-methyladenine DNA glycosylase (AAG, ANPG, MPG) | 0 | DIRECT |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| RNase P subunit p29-like | 0 | DIRECT |
| Ureidoglycolate hydrolase AllA | 0 | DIRECT |
| Penta-EF-hand proteins | 0 | DIRECT |
| Cellulose-binding domain family III | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| GW domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| N-terminal domain of RNase HI | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| YfcE-like | 0 | DIRECT |
| G proteins | 0 | DIRECT |
| Replicase NSP9 | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| C-terminal, Zn-finger domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Type 1 signal peptidase | 0 | DIRECT |
| Retrovirus capsid protein C-terminal domain | 0 | DIRECT |
| FMDV leader protease | 0 | DIRECT |
| ABC transporter ATPase domain-like | 0 | DIRECT |
| Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
| Inosicase | 0 | DIRECT |
| Patatin | 0 | DIRECT |
| Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | DIRECT |
| AbfB domain | 0 | DIRECT |
| Replication initiation protein E1 | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Staphylococcal nuclease | 0 | DIRECT |
| EAL domain | 0 | DIRECT |
| Influenza hemagglutinin (stalk) | 0 | DIRECT |
| GpdQ-like | 0 | DIRECT |
| Rpp14/Pop5-like | 0 | DIRECT |
| Clostridium neurotoxins, the second last domain | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
| TNF-alpha converting enzyme, TACE, catalytic domain | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Leucine aminopeptidase, C-terminal domain | 0 | DIRECT |
| 2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain | 0 | DIRECT |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| Nuclease | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Germination protease | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| CAF1-like ribonuclease | 0 | DIRECT |
| ABC-transporter additional domain | 0 | DIRECT |
| Eng V-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| AglA-like glucosidase | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| Viral proteases | 0 | DIRECT |
| RNA helicase | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| M48USP-like | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Fibronectin type I module | 0 | DIRECT |
| SAH/MTA deaminase-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Acylphosphatase-like | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
| Histidinol phosphatase-like | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| C-type lysozyme | 0 | DIRECT |
| CBM22 | 0 | DIRECT |
| DNA-binding domain from rap30 | 0 | DIRECT |
| Peptidoglycan hydrolase LytM | 0 | DIRECT |
| Prolyl oligopeptidase, N-terminal domain | 0 | DIRECT |
| Eukaryotic proteases | 0 | DIRECT |
| Middle domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| RNase III catalytic domain-like | 0 | DIRECT |
| Biotin biosynthesis protein BioH | 0 | DIRECT |
| Tail specific protease, catalytic domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| Acetylcholinesterase-like | 0 | DIRECT |
| MtnX-like | 0 | DIRECT |
| Helicase-like "domain" of reverse gyrase | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| PBP5 C-terminal domain-like | 0 | DIRECT |
| Dimethylarginine dimethylaminohydrolase DDAH | 0 | DIRECT |
| beta-Phosphoglucomutase-like | 0 | DIRECT |
| Enolase-phosphatase E1 | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Methylesterase CheB, C-terminal domain | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Family 19 glycosidase | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Clostridium neurotoxins, C-terminal domain | 0 | DIRECT |
| Immunodeficiency virus matrix proteins | 0 | DIRECT |
| Fungal ribonucleases | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| MMP N-terminal domain | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0 | DIRECT |
| Ku70 subunit middle domain | 0 | DIRECT |
| alpha-L-arabinanase-like | 0 | DIRECT |
| Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Prokaryotic proteases | 0 | DIRECT |
| beta-Galactosidase/glucuronidase, N-terminal domain | 0 | DIRECT |
| DNA helicase RuvA subunit, middle domain | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| Ku80 subunit N-terminal domain | 0 | DIRECT |
| Carboxylesterase | 0 | DIRECT |
| Nsp15 N-terminal domain-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Glycosyl hydrolases family 35 catalytic domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Thermolysin-like | 0 | DIRECT |
| HRDC domain from helicases | 0 | DIRECT |
| Cellulose docking domain, dockering | 0 | DIRECT |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
| Ppx associated domain | 0 | DIRECT |
| AstE/AspA-like | 0 | DIRECT |
| Staphopain B, prodomain | 0 | DIRECT |
| Porphyromonas-type peptidylarginine deiminase | 0 | DIRECT |
| Alpha-L-arabinofuranosidase B, N-terminal domain | 0 | DIRECT |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | DIRECT |
| NodB-like polysaccharide deacetylase | 0 | DIRECT |
| Dienelactone hydrolase | 0 | DIRECT |
| Carbon-carbon bond hydrolase | 0 | DIRECT |
| RecQ helicase DNA-binding domain-like | 0 | DIRECT |
| RNA-dependent RNA-polymerase | 0 | DIRECT |
| Astacin | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
| Peptidyl-tRNA hydrolase II | 0 | DIRECT |
| SARS Nsp1-like | 0 | DIRECT |
| HTLV-II matrix protein | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| Glycosyl hydrolases family 6, cellulases | 0 | DIRECT |
| Outer membrane phospholipase A (OMPLA) | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Toprim domain | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| LexA repressor, N-terminal DNA-binding domain | 0 | DIRECT |
| Putative glucosidase YicI, domain 3 | 0 | DIRECT |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Glycosyl hydrolases family 32 C-terminal domain | 0 | DIRECT |
| Zn metallo-beta-lactamase | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Imidazolonepropionase-like | 0 | DIRECT |
| Composite domain of glycosyl hydrolase families 5, 30, 39 and 51 | 0 | DIRECT |
| PepX C-terminal domain-like | 0 | DIRECT |
| Nitrilase | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Beta-galactosidase LacA, domains 4 and 5 | 0 | DIRECT |
| Prolyl oligopeptidase, C-terminal domain | 0 | DIRECT |
| PUG domain | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| beta-N-acetylhexosaminidase domain | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Gingipain R (RgpB), N-terminal domain | 0 | DIRECT |
| Fungal lipases | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| HisE-like (PRA-PH) | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| beta-Galactosidase, domain 5 | 0 | DIRECT |
| Renal dipeptidase | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Extended AAA-ATPase domain | 0 | DIRECT |
| ADP ribosyl cyclase-like | 0 | DIRECT |
| Ribonuclease A-like | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Family 1 of glycosyl hydrolase | 0 | DIRECT |
| Clp protease, ClpP subunit | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| SurE-like | 0 | DIRECT |
| Low-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| mRNA triphosphatase CET1 | 0 | DIRECT |
| EF-hand modules in multidomain proteins | 0 | DIRECT |
| Ppx/GppA phosphatase | 0 | DIRECT |
| HAD-related | 0 | DIRECT |
| Lysophospholipase | 0 | DIRECT |
| CheD-like | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Holliday junction resolvase RusA | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| ComB-like | 0 | DIRECT |
| Fungal zinc peptidase | 0 | DIRECT |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | DIRECT |
| LexA-related | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| ITPase (Ham1) | 0 | DIRECT |
| Hypothetical esterase YJL068C | 0 | DIRECT |
| 5' nucleotidase-like | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Helicase DNA-binding domain | 0 | DIRECT |
| NSP3A-like | 0 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| NagZ-like | 0 | DIRECT |
| Phage lysozyme | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Glucoamylase | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| A4 beta-galactosidase middle domain | 0 | DIRECT |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | DIRECT |
| Sialidases (neuraminidases) | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Cellulose-binding domain family II | 0 | DIRECT |
| Dac-like | 0 | DIRECT |
| Extended PAW domain | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| YicI N-terminal domain-like | 0 | DIRECT |
| Retroviral protease (retropepsin) | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| Predicted hydrolases Cof | 0 | DIRECT |
| Phosphonoacetaldehyde hydrolase-like | 0 | DIRECT |
| Coronavirus NSP7-like | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| Hevein-like agglutinin (lectin) domain | 0 | DIRECT |
| beta-N-acetylhexosaminidase catalytic domain | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Carbohydrate binding domain | 0 | DIRECT |
| Alkaline phosphatase | 0 | DIRECT |
| Reverse transcriptase | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| GTP cyclohydrolase I | 0 | DIRECT |
| Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Cutinase-like | 0 | DIRECT |
| Imidazolonepropionase-like | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| Bacterial lipase | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| SGL-like | 0 | DIRECT |
| Type I dockerin domain | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| CheY-related | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Caliciviridae-like VP | 0 | DIRECT |
| XseB-like | 0 | DIRECT |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | DIRECT |
| Aspartyl dipeptidase PepE | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| RNase P protein | 0 | DIRECT |
| Dihydroorotase | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| Allantoicase repeat | 0 | DIRECT |
| Bee venom hyaluronidase | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| 1,4-beta-N-acetylmuraminidase | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Kringle modules | 0 | DIRECT |
| Leucine rich effector protein YopM | 0 | DIRECT |
| GUCT domain | 0 | DIRECT |
| ADPRibase-Mn-like | 0 | DIRECT |
| alpha-Subunit of urease | 0 | DIRECT |
| Galacturonase | 0 | DIRECT |
| Purple acid phosphatase-like | 0 | DIRECT |
| FolH catalytic domain-like | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Carbamilase | 0 | DIRECT |
| Endonuclease IV | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Leukotriene A4 hydrolase C-terminal domain | 0 | DIRECT |
| Coronavirus NSP10-like | 0 | DIRECT |
| Colipase-binding domain | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Glycosyl hydrolase family 7 catalytic core | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| Succinylarginine dihydrolase-like | 0 | DIRECT |
| Neutral endopeptidase (neprilysin) | 0 | DIRECT |
| Class B acid phosphatase, AphA | 0 | DIRECT |
| Family 9 carbohydrate-binding module, CBD9 | 0 | DIRECT |
| Cytidine deaminase | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| Serine-carboxyl proteinase, SCP | 0 | DIRECT |
| RecG "wedge" domain | 0 | DIRECT |
| Penicillin acylase, catalytic domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| tRNA-intron endonuclease N-terminal domain-like | 0 | DIRECT |
| Peptidyl-tRNA hydrolase-like | 0 | DIRECT |
| Arginine deiminase | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
| Uracil-DNA glycosylase | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Ku80 subunit middle domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Nucleoside hydrolase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Sphingomyelin phosphodiesterase-like | 0 | DIRECT |
| RNase D C-terminal domains | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Clostridium neurotoxins, catalytic domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| CDH-like | 0 | DIRECT |
| Retroviral integrase, catalytic domain | 0 | DIRECT |
| Virulence factor P.69 pertactin | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Ribonuclease Rh-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Peptidyl-tRNA hydrolase domain | 0 | DIRECT |
| Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Integrin A (or I) domain | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Aminopeptidase/glucanase lid domain | 0 | DIRECT |
| Exodeoxyribonuclease V beta chain (RecC), C-terminal domain | 0 | DIRECT |
| Xylanase/endoglucanase 11/12 | 0 | DIRECT |
| Viral cysteine protease of trypsin fold | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| Alpha-toxin, C-terminal domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Cellulose-binding domain | 0 | DIRECT |
| Leishmanolysin | 0 | DIRECT |
| Insect phospholipase A2 | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Gastric lipase | 0 | DIRECT |
| mRNA cap methylase | 0 | DIRECT |
| PepX catalytic domain-like | 0 | DIRECT |
| RNase P subunit p30 | 0 | DIRECT |
| Cellulases catalytic domain | 0 | DIRECT |
| Putative alpha-L-fucosidase, catalytic domain | 0 | DIRECT |
| SAH/MTA deaminase-like | 0 | DIRECT |
| Phospholipase C | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Trehalase-like | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| alpha-D-glucuronidase/Hyaluronidase catalytic domain | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| Putative serine hydrolase Ydr428c | 0 | DIRECT |
| N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain | 0 | DIRECT |
| RNase Z-like | 0 | DIRECT |
| Ku70 subunit N-terminal domain | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| Nodaviridae-like VP | 0 | DIRECT |
| MATH domain | 0 | DIRECT |
| EGF-type module | 1.746e-16 | DIRECT |
| cAMP-binding domain | 3.476e-16 | DIRECT |
| Ubiquitin-related | 3.476e-16 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 3.476e-16 | DIRECT |
| Mug-like | 0.00000000000000121 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0.000000000000003089 | DIRECT |
| LysM domain | 0.000000000000005475 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.0000000000000234 | DIRECT |
| MAM domain | 0.00000000000002508 | DIRECT |
| Haloalkane dehalogenase | 0.00000000000002508 | DIRECT |
| GAF domain | 0.00000000001185 | DIRECT |
| Nitrous oxide reductase, N-terminal domain | 0.00000000002216 | DIRECT |
| Caspase recruitment domain, CARD | 0.00000000006356 | DIRECT |
| Myotubularin-like phosphatases | 0.0000000001407 | DIRECT |
| Purine and uridine phosphorylases | 0.000000001913 | DIRECT |
| Serralysin-like metalloprotease, C-terminal domain | 0.000000002508 | DIRECT |
| Trehalose-phosphatase | 0.0000000781 | DIRECT |
| LDL receptor-like module | 0.0000001832 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0.0000003609 | DIRECT |
| HCP-like | 0.0000003609 | DIRECT |
| Tudor domain | 0.000001004 | DIRECT |
| 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB | 0.000001168 | DIRECT |
| Fibronectin type III | 0.000001549 | DIRECT |
| Acetylhydrolase | 0.000001611 | DIRECT |
| HD domain | 0.000002749 | DIRECT |
| SPRY domain | 0.000003105 | DIRECT |
| Chromo domain | 0.00001061 | DIRECT |
| SAP domain | 0.00001415 | DIRECT |
| UBA domain | 0.00002545 | DIRECT |
| Starch-binding domain | 0.00003125 | DIRECT |
| Third domain of FERM | 0.00005741 | DIRECT |
| Acyl-carrier protein (ACP) | 0.0001423 | DIRECT |
| CYTH domain | 0.0001423 | DIRECT |
| Family 6 carbohydrate binding module, CBM6 | 0.0002018 | DIRECT |
| MYND zinc finger | 0.0002018 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0.0002753 | DIRECT |
| TENA/THI-4 | 0.0003287 | DIRECT |
| Ran binding protein zinc finger-like | 0.0004458 | DIRECT |
| First domain of FERM | 0.0004838 | DIRECT |
| RibD C-terminal domain-like | 0.0004874 | DIRECT |
| Transglutaminase core | 0.0005665 | DIRECT |
| 4-alpha-glucanotransferase, N-terminal domain | 0.0007895 | DIRECT |
| DEK C-terminal domain | 0.0007895 | DIRECT |
| DNase I-like | 0.0008857 | DIRECT |
| DNA repair glycosylase, 2 C-terminal domains | 0.0029 | INHERITED FROM: DNA-3-methyladenine glycosylase II || Glycosylases || Hydrolyzing N-glycosyl compounds |
| Ankyrin repeat | 0.003902 | INHERITED FROM: Carboxylic ester hydrolases || Glutaminase || NAD(+) diphosphatase || In linear amides || In phosphorous-containing anhydrides || Acting on carbon-nitrogen bonds, other than peptid |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.005427 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Probable phosphatase YrbI | 0.008166 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || 3-deoxy-manno-octulosonate-8-phosphatase |
| Intein (protein splicing domain) | 0.009321 | INHERITED FROM: DNA helicase || Acting on acid anhydrides |
| AlkB-like | 0.009334 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase || Acting on acid anhydrides |
| Second domain of FERM | 0.01212 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.01425 | INHERITED FROM: Acting on ester bonds || Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| DnaQ-like 3'-5' exonuclease | 0.01519 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoeste || Exodeoxyribonuclease III || Exoribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Ribonuclease D || Exodeoxyribonuclease I || Ribonuclease H || Poly(A)-specific ribonuclease |
| PDZ domain | 0.02281 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Ricin B-like | 0.02526 | INHERITED FROM: Glycosylases || rRNA N-glycosylase || Hydrolyzing N-glycosyl compounds |
| RelA/SpoT domain | 0.03096 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
| MaoC-like | 0.06914 | INHERITED FROM: Acting on ester bonds || Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| PX domain | 0.08134 | INHERITED FROM: Phospholipase D || Acting on ester bonds || Phosphoric diester hydrolases |
| Canonical RBD | 0.0819 | INHERITED FROM: Exoribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Phosphoinositide 5-phosphatase || Poly(A)-specific ribonuclease |
| Glycosyl hydrolases family 16 | 0.1215 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || Licheninase |
| CoA transferase alpha subunit-like | 0.1971 | INHERITED FROM: Acetyl-CoA hydrolase || Acting on ester bonds || Thiolester hydrolases |
| FAH | 0.1978 | INHERITED FROM: Acting on carbon-carbon bonds || Fumarylacetoacetase || Acylpyruvate hydrolase |
| WW domain | 0.6369 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
| Pyruvate oxidase and decarboxylase, middle domain | 0.6393 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| FabD-like | 0.8323 | INHERITED FROM: Acting on ester bonds || Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| Prokaryotic type I DNA topoisomerase | 0.862 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase || Acting on acid anhydrides |
| I set domains | 0.88 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Growth factor receptor domain | 0.9891 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Furin || Serine endopeptidases |
| Cystathionine synthase-like | 1 | INHERITED FROM: Acting on carbon-carbon bonds || Kynureninase |
| Tyrosine-dependent oxidoreductases | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Pyruvate oxidase and decarboxylase PP module | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| PHD domain | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase |
| Crotonase-like | 1 | INHERITED FROM: 3-hydroxyisobutyryl-CoA hydrolase || Thiolester hydrolases |
| Thiolase-related | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| BC N-terminal domain-like | 1 | INHERITED FROM: Dihydroorotase |
| DNA polymerase I | 1 | INHERITED FROM: Ribonuclease H || Endoribonucleases producing 5'-phosphomonoesters |
| SH3-domain | 1 | INHERITED FROM: Phosphoinositide phospholipase C || Phosphoric diester hydrolases |
| Pyruvate oxidase and decarboxylase Pyr module | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| Tetratricopeptide repeat (TPR) | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoprotein phosphatase |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| E-set domains of sugar-utilizing enzymes | 1 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehal || Pullulanase |
| SH2 domain | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoinositide phospholipase C || Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric diester hydrolases || Phosphatidylinositol-3,4,5-trisphosphate 5-phospha |
| BC ATP-binding domain-like | 1 | INHERITED FROM: Dihydroorotase |
| Class I glutamine amidotransferases (GAT) | 1 | INHERITED FROM: Gamma-glutamyl hydrolase |
| Cofactor-dependent phosphoglycerate mutase | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Fructose-2,6-bisphosphate 2-phosphatase || Bisphosphoglycerate phosphatase |
| SAM (sterile alpha motif) domain | 1 | INHERITED FROM: Phosphatidylinositol-3,4,5-trisphosphate 5-phospha |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: 1-aminocyclopropane-1-carboxylate deaminase || In other compounds || Acting on carbon-nitrogen bonds, other than peptid |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| Cold shock DNA-binding domain-like | 1 | INHERITED FROM: Exoribonucleases producing 5'-phosphomonoesters || Ribonuclease E || Acting on ester bonds || Exoribonuclease II |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| LDH N-terminal domain-like | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase |
| AraD-like aldolase/epimerase | 1 | INHERITED FROM: Acireductone synthase |
| Carbonic anhydrase | 1 | INHERITED FROM: Protein-tyrosine-phosphatase |
| L-histidinol dehydrogenase HisD | 1 | INHERITED FROM: Phosphoribosyl-AMP cyclohydrolase || Phosphoribosyl-ATP diphosphatase |
| Nitrogenase iron protein-like | 1 | INHERITED FROM: Arsenite-transporting ATPase |
| Imidazole glycerol phosphate dehydratase | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Histidinol-phosphatase |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Mammalian PLC | 0 | Direct |
| Coronavirus NSP8-like | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Peptidoglycan binding domain, PGBD | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| RuvC resolvase | 0 | Direct |
| Nsp15 C-terminal domain-like | 0 | Direct |
| Manganese-dependent inorganic pyrophosphatase (family II) | 0 | Direct |
| Plant cytotoxins | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| Fibronectin type II module | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| MutT-like | 0 | Direct |
| Pyrimidine 5'-nucleotidase (UMPH-1) | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| Type 2 phosphatidic acid phosphatase, PAP2 | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| Thioesterases | 0 | Direct |
| Class II viral fusion proteins C-terminal domain | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0 | Direct |
| Leucine aminopeptidase (Aminopeptidase A), N-terminal domain | 0 | Direct |
| TMV-like viral coat proteins | 0 | Direct |
| Glycosyl hydrolases family 32 N-terminal domain | 0 | Direct |
| NADH pyrophosphatase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Beta-galactosidase LacA, domain 2 | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| GlpX-like bacterial fructose-1,6-bisphosphatase | 0 | Direct |
| Pancreatic lipase, N-terminal domain | 0 | Direct |
| LmbE-like | 0 | Direct |
| HtrA-like serine proteases | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| alpha-subunit of urease, catalytic domain | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Subtilase propeptides/inhibitors | 0 | Direct |
| G-type lysozyme | 0 | Direct |
| Phosphoserine phosphatase | 0 | Direct |
| Pectin methylesterase | 0 | Direct |
| DNA helicase RuvA subunit, N-terminal domain | 0 | Direct |
| Serralysin-like metalloprotease, catalytic (N-terminal) domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
| alpha-D-glucuronidase, N-terminal domain | 0 | Direct |
| Proline iminopeptidase-like | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| Herpes virus serine proteinase, assemblin | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| VanX-like | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| 3-methyladenine DNA glycosylase (AAG, ANPG, MPG) | 0 | Direct |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| RNase P subunit p29-like | 0 | Direct |
| Ureidoglycolate hydrolase AllA | 0 | Direct |
| Penta-EF-hand proteins | 0 | Direct |
| Cellulose-binding domain family III | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| GW domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| N-terminal domain of RNase HI | 0 | Direct |
| R3H domain | 0 | Direct |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| YfcE-like | 0 | Direct |
| G proteins | 0 | Direct |
| Replicase NSP9 | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| C-terminal, Zn-finger domain of MutM-like DNA repair proteins | 0 | Direct |
| Type 1 signal peptidase | 0 | Direct |
| Retrovirus capsid protein C-terminal domain | 0 | Direct |
| FMDV leader protease | 0 | Direct |
| ABC transporter ATPase domain-like | 0 | Direct |
| Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
| Inosicase | 0 | Direct |
| Patatin | 0 | Direct |
| Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | Direct |
| AbfB domain | 0 | Direct |
| Replication initiation protein E1 | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Staphylococcal nuclease | 0 | Direct |
| EAL domain | 0 | Direct |
| Influenza hemagglutinin (stalk) | 0 | Direct |
| GpdQ-like | 0 | Direct |
| Rpp14/Pop5-like | 0 | Direct |
| Clostridium neurotoxins, the second last domain | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
| TNF-alpha converting enzyme, TACE, catalytic domain | 0 | Direct |
| Papain-like | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Leucine aminopeptidase, C-terminal domain | 0 | Direct |
| 2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain | 0 | Direct |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
| Putative cyclase | 0 | Direct |
| Nuclease | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Germination protease | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| RNB domain-like | 0 | Direct |
| CAF1-like ribonuclease | 0 | Direct |
| ABC-transporter additional domain | 0 | Direct |
| Eng V-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| AglA-like glucosidase | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| Viral proteases | 0 | Direct |
| RNA helicase | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| dUTPase-like | 0 | Direct |
| M48USP-like | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Fibronectin type I module | 0 | Direct |
| SAH/MTA deaminase-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Acylphosphatase-like | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
| Histidinol phosphatase-like | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| C-type lysozyme | 0 | Direct |
| CBM22 | 0 | Direct |
| DNA-binding domain from rap30 | 0 | Direct |
| Peptidoglycan hydrolase LytM | 0 | Direct |
| Prolyl oligopeptidase, N-terminal domain | 0 | Direct |
| Eukaryotic proteases | 0 | Direct |
| Middle domain of MutM-like DNA repair proteins | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| RNase III catalytic domain-like | 0 | Direct |
| Biotin biosynthesis protein BioH | 0 | Direct |
| Tail specific protease, catalytic domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| NagD-like | 0 | Direct |
| Acetylcholinesterase-like | 0 | Direct |
| MtnX-like | 0 | Direct |
| Helicase-like "domain" of reverse gyrase | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| PBP5 C-terminal domain-like | 0 | Direct |
| Dimethylarginine dimethylaminohydrolase DDAH | 0 | Direct |
| beta-Phosphoglucomutase-like | 0 | Direct |
| Enolase-phosphatase E1 | 0 | Direct |
| Trefoil | 0 | Direct |
| Methylesterase CheB, C-terminal domain | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Family 19 glycosidase | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Clostridium neurotoxins, C-terminal domain | 0 | Direct |
| Immunodeficiency virus matrix proteins | 0 | Direct |
| Fungal ribonucleases | 0 | Direct |
| MPP-like | 0 | Direct |
| MMP N-terminal domain | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Tandem AAA-ATPase domain | 0 | Direct |
| Ku70 subunit middle domain | 0 | Direct |
| alpha-L-arabinanase-like | 0 | Direct |
| Beta-galactosidase LacA, domain 3 | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Prokaryotic proteases | 0 | Direct |
| beta-Galactosidase/glucuronidase, N-terminal domain | 0 | Direct |
| DNA helicase RuvA subunit, middle domain | 0 | Direct |
| Adenain-like | 0 | Direct |
| Ku80 subunit N-terminal domain | 0 | Direct |
| Carboxylesterase | 0 | Direct |
| Nsp15 N-terminal domain-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Glycosyl hydrolases family 35 catalytic domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Thermolysin-like | 0 | Direct |
| HRDC domain from helicases | 0 | Direct |
| Cellulose docking domain, dockering | 0 | Direct |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
| Ppx associated domain | 0 | Direct |
| AstE/AspA-like | 0 | Direct |
| Staphopain B, prodomain | 0 | Direct |
| Porphyromonas-type peptidylarginine deiminase | 0 | Direct |
| Alpha-L-arabinofuranosidase B, N-terminal domain | 0 | Direct |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | Direct |
| NodB-like polysaccharide deacetylase | 0 | Direct |
| Dienelactone hydrolase | 0 | Direct |
| Carbon-carbon bond hydrolase | 0 | Direct |
| RecQ helicase DNA-binding domain-like | 0 | Direct |
| RNA-dependent RNA-polymerase | 0 | Direct |
| Astacin | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
| Peptidyl-tRNA hydrolase II | 0 | Direct |
| SARS Nsp1-like | 0 | Direct |
| HTLV-II matrix protein | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| Glycosyl hydrolases family 6, cellulases | 0 | Direct |
| Outer membrane phospholipase A (OMPLA) | 0 | Direct |
| PDEase | 0 | Direct |
| Toprim domain | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| LexA repressor, N-terminal DNA-binding domain | 0 | Direct |
| Putative glucosidase YicI, domain 3 | 0 | Direct |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Glycosyl hydrolases family 32 C-terminal domain | 0 | Direct |
| Zn metallo-beta-lactamase | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Imidazolonepropionase-like | 0 | Direct |
| Composite domain of glycosyl hydrolase families 5, 30, 39 and 51 | 0 | Direct |
| PepX C-terminal domain-like | 0 | Direct |
| Nitrilase | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Beta-galactosidase LacA, domains 4 and 5 | 0 | Direct |
| Prolyl oligopeptidase, C-terminal domain | 0 | Direct |
| PUG domain | 0 | Direct |
| Elongation factors | 0 | Direct |
| beta-N-acetylhexosaminidase domain | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Gingipain R (RgpB), N-terminal domain | 0 | Direct |
| Fungal lipases | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| HisE-like (PRA-PH) | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| beta-Galactosidase, domain 5 | 0 | Direct |
| Renal dipeptidase | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Extended AAA-ATPase domain | 0 | Direct |
| ADP ribosyl cyclase-like | 0 | Direct |
| Ribonuclease A-like | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Family 1 of glycosyl hydrolase | 0 | Direct |
| Clp protease, ClpP subunit | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| SurE-like | 0 | Direct |
| Low-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| mRNA triphosphatase CET1 | 0 | Direct |
| EF-hand modules in multidomain proteins | 0 | Direct |
| Ppx/GppA phosphatase | 0 | Direct |
| HAD-related | 0 | Direct |
| Lysophospholipase | 0 | Direct |
| CheD-like | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Holliday junction resolvase RusA | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| ComB-like | 0 | Direct |
| Fungal zinc peptidase | 0 | Direct |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | Direct |
| LexA-related | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| ITPase (Ham1) | 0 | Direct |
| Hypothetical esterase YJL068C | 0 | Direct |
| 5' nucleotidase-like | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Helicase DNA-binding domain | 0 | Direct |
| NSP3A-like | 0 | Direct |
| Plant invertase/pectin methylesterase inhibitor | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Creatininase | 0 | Direct |
| NagZ-like | 0 | Direct |
| Phage lysozyme | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| GLA-domain | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Glucoamylase | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| A4 beta-galactosidase middle domain | 0 | Direct |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | Direct |
| Sialidases (neuraminidases) | 0 | Direct |
| LON domain-like | 0 | Direct |
| Cellulose-binding domain family II | 0 | Direct |
| Dac-like | 0 | Direct |
| Extended PAW domain | 0 | Direct |
| Subtilases | 0 | Direct |
| YicI N-terminal domain-like | 0 | Direct |
| Retroviral protease (retropepsin) | 0 | Direct |
| Macro domain | 0 | Direct |
| Predicted hydrolases Cof | 0 | Direct |
| Phosphonoacetaldehyde hydrolase-like | 0 | Direct |
| Coronavirus NSP7-like | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| Hevein-like agglutinin (lectin) domain | 0 | Direct |
| beta-N-acetylhexosaminidase catalytic domain | 0 | Direct |
| Pepsin-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Carbohydrate binding domain | 0 | Direct |
| Alkaline phosphatase | 0 | Direct |
| Reverse transcriptase | 0 | Direct |
| Type II chitinase | 0 | Direct |
| GTP cyclohydrolase I | 0 | Direct |
| Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Cutinase-like | 0 | Direct |
| Imidazolonepropionase-like | 0 | Direct |
| Glutaminase | 0 | Direct |
| NagB-like | 0 | Direct |
| Bacterial lipase | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| RibA-like | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| SGL-like | 0 | Direct |
| Type I dockerin domain | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| CheY-related | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Caliciviridae-like VP | 0 | Direct |
| XseB-like | 0 | Direct |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | Direct |
| Aspartyl dipeptidase PepE | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| RNase P protein | 0 | Direct |
| Dihydroorotase | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| Allantoicase repeat | 0 | Direct |
| Bee venom hyaluronidase | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| 1,4-beta-N-acetylmuraminidase | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Kringle modules | 0 | Direct |
| Leucine rich effector protein YopM | 0 | Direct |
| GUCT domain | 0 | Direct |
| ADPRibase-Mn-like | 0 | Direct |
| alpha-Subunit of urease | 0 | Direct |
| Galacturonase | 0 | Direct |
| Purple acid phosphatase-like | 0 | Direct |
| FolH catalytic domain-like | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Carbamilase | 0 | Direct |
| Endonuclease IV | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Leukotriene A4 hydrolase C-terminal domain | 0 | Direct |
| Coronavirus NSP10-like | 0 | Direct |
| Colipase-binding domain | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Glycosyl hydrolase family 7 catalytic core | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| Succinylarginine dihydrolase-like | 0 | Direct |
| Neutral endopeptidase (neprilysin) | 0 | Direct |
| Class B acid phosphatase, AphA | 0 | Direct |
| Family 9 carbohydrate-binding module, CBD9 | 0 | Direct |
| Cytidine deaminase | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| Serine-carboxyl proteinase, SCP | 0 | Direct |
| RecG "wedge" domain | 0 | Direct |
| Penicillin acylase, catalytic domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| tRNA-intron endonuclease N-terminal domain-like | 0 | Direct |
| Peptidyl-tRNA hydrolase-like | 0 | Direct |
| Arginine deiminase | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| beta-Galactosidase/glucuronidase domain | 0 | Direct |
| Uracil-DNA glycosylase | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Ku80 subunit middle domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Nucleoside hydrolase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Sphingomyelin phosphodiesterase-like | 0 | Direct |
| RNase D C-terminal domains | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Clostridium neurotoxins, catalytic domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| CDH-like | 0 | Direct |
| Retroviral integrase, catalytic domain | 0 | Direct |
| Virulence factor P.69 pertactin | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Ribonuclease Rh-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Peptidyl-tRNA hydrolase domain | 0 | Direct |
| Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Integrin A (or I) domain | 0 | Direct |
| PA domain | 0 | Direct |
| Aminopeptidase/glucanase lid domain | 0 | Direct |
| Exodeoxyribonuclease V beta chain (RecC), C-terminal domain | 0 | Direct |
| Xylanase/endoglucanase 11/12 | 0 | Direct |
| Viral cysteine protease of trypsin fold | 0 | Direct |
| GRAM domain | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| Alpha-toxin, C-terminal domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Cellulose-binding domain | 0 | Direct |
| Leishmanolysin | 0 | Direct |
| Insect phospholipase A2 | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Gastric lipase | 0 | Direct |
| mRNA cap methylase | 0 | Direct |
| PepX catalytic domain-like | 0 | Direct |
| RNase P subunit p30 | 0 | Direct |
| Cellulases catalytic domain | 0 | Direct |
| Putative alpha-L-fucosidase, catalytic domain | 0 | Direct |
| SAH/MTA deaminase-like | 0 | Direct |
| Phospholipase C | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Trehalase-like | 0 | Direct |
| HisI-like | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| beta-glycanases | 0 | Direct |
| alpha-D-glucuronidase/Hyaluronidase catalytic domain | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| Putative serine hydrolase Ydr428c | 0 | Direct |
| N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain | 0 | Direct |
| RNase Z-like | 0 | Direct |
| Ku70 subunit N-terminal domain | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| Nodaviridae-like VP | 0 | Direct |
| MATH domain | 0 | Direct |
| EGF-type module | 1.746e-16 | Direct |
| cAMP-binding domain | 3.476e-16 | Direct |
| Ubiquitin-related | 3.476e-16 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 3.476e-16 | Direct |
| Mug-like | 0.00000000000000121 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0.000000000000003089 | Direct |
| LysM domain | 0.000000000000005475 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.0000000000000234 | Direct |
| MAM domain | 0.00000000000002508 | Direct |
| Haloalkane dehalogenase | 0.00000000000002508 | Direct |
| GAF domain | 0.00000000001185 | Direct |
| Nitrous oxide reductase, N-terminal domain | 0.00000000002216 | Direct |
| Caspase recruitment domain, CARD | 0.00000000006356 | Direct |
| Myotubularin-like phosphatases | 0.0000000001407 | Direct |
| Purine and uridine phosphorylases | 0.000000001913 | Direct |
| Serralysin-like metalloprotease, C-terminal domain | 0.000000002508 | Direct |
| Trehalose-phosphatase | 0.0000000781 | Direct |
| LDL receptor-like module | 0.0000001832 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0.0000003609 | Direct |
| HCP-like | 0.0000003609 | Direct |
| Tudor domain | 0.000001004 | Direct |
| 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB | 0.000001168 | Direct |
| Fibronectin type III | 0.000001549 | Direct |
| Acetylhydrolase | 0.000001611 | Direct |
| HD domain | 0.000002749 | Direct |
| SPRY domain | 0.000003105 | Direct |
| Chromo domain | 0.00001061 | Direct |
| SAP domain | 0.00001415 | Direct |
| UBA domain | 0.00002545 | Direct |
| Starch-binding domain | 0.00003125 | Direct |
| Third domain of FERM | 0.00005741 | Direct |
| Acyl-carrier protein (ACP) | 0.0001423 | Direct |
| CYTH domain | 0.0001423 | Direct |
| Family 6 carbohydrate binding module, CBM6 | 0.0002018 | Direct |
| MYND zinc finger | 0.0002018 | Direct |
| Pleckstrin-homology domain (PH domain) | 0.0002753 | Direct |
| TENA/THI-4 | 0.0003287 | Direct |
| Ran binding protein zinc finger-like | 0.0004458 | Direct |
| First domain of FERM | 0.0004838 | Direct |
| RibD C-terminal domain-like | 0.0004874 | Direct |
| Transglutaminase core | 0.0005665 | Direct |
| 4-alpha-glucanotransferase, N-terminal domain | 0.0007895 | Direct |
| DEK C-terminal domain | 0.0007895 | Direct |
| DNase I-like | 0.0008857 | Direct |
| DNA repair glycosylase, 2 C-terminal domains | 0.0029 | Inherited |
| Ankyrin repeat | 0.003902 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.005427 | Inherited |
| Probable phosphatase YrbI | 0.008166 | Inherited |
| Intein (protein splicing domain) | 0.009321 | Inherited |
| AlkB-like | 0.009334 | Inherited |
| Second domain of FERM | 0.01212 | Inherited |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.01425 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.01519 | Inherited |
| PDZ domain | 0.02281 | Inherited |
| Ricin B-like | 0.02526 | Inherited |
| RelA/SpoT domain | 0.03096 | Inherited |
| MaoC-like | 0.06914 | Inherited |
| PX domain | 0.08134 | Inherited |
| Canonical RBD | 0.0819 | Inherited |
| Glycosyl hydrolases family 16 | 0.1215 | Inherited |
| CoA transferase alpha subunit-like | 0.1971 | Inherited |
| FAH | 0.1978 | Inherited |
| WW domain | 0.6369 | Inherited |
| Pyruvate oxidase and decarboxylase, middle domain | 0.6393 | Inherited |
| FabD-like | 0.8323 | Inherited |
| Prokaryotic type I DNA topoisomerase | 0.862 | Inherited |
| I set domains | 0.88 | Inherited |
| Growth factor receptor domain | 0.9891 | Inherited |
| Cystathionine synthase-like | 1 | Inherited |
| Tyrosine-dependent oxidoreductases | 1 | Inherited |
| Pyruvate oxidase and decarboxylase PP module | 1 | Inherited |
| PHD domain | 1 | Inherited |
| Crotonase-like | 1 | Inherited |
| Thiolase-related | 1 | Inherited |
| BC N-terminal domain-like | 1 | Inherited |
| DNA polymerase I | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| Pyruvate oxidase and decarboxylase Pyr module | 1 | Inherited |
| Tetratricopeptide repeat (TPR) | 1 | Inherited |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | Inherited |
| E-set domains of sugar-utilizing enzymes | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| BC ATP-binding domain-like | 1 | Inherited |
| Class I glutamine amidotransferases (GAT) | 1 | Inherited |
| Cofactor-dependent phosphoglycerate mutase | 1 | Inherited |
| SAM (sterile alpha motif) domain | 1 | Inherited |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| Cold shock DNA-binding domain-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| LDH N-terminal domain-like | 1 | Inherited |
| AraD-like aldolase/epimerase | 1 | Inherited |
| Carbonic anhydrase | 1 | Inherited |
| L-histidinol dehydrogenase HisD | 1 | Inherited |
| Nitrogenase iron protein-like | 1 | Inherited |
| Imidazole glycerol phosphate dehydratase | 1 | Inherited |
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A presence/absence matrix is generated using protein domains and supradomains
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (Not in SPEO)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| LigT-like | 0 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 0 | DIRECT |
| PUG domain-like | 0 | DIRECT |
| Cellulose-binding domain | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Outer membrane phospholipase A (OMPLA) | 0 | DIRECT |
| Invasin/intimin cell-adhesion fragments | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| DHH phosphoesterases | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| Dcp2 domain-like | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Voltage-gated potassium channels | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Coronavirus NSP8-like | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Influenza hemagglutinin (stalk) | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| Origin of replication-binding domain, RBD-like | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Autotransporter | 0 | DIRECT |
| Sec-C motif | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| tRNA-intron endonuclease N-terminal domain-like | 0 | DIRECT |
| Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
| L9 N-domain-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| TRAF domain-like | 0 | DIRECT |
| all-alpha NTP pyrophosphatases | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| Bacterial GAP domain | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| MOP-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Holliday junction resolvase RusA | 0 | DIRECT |
| Carbohydrate-binding domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Saposin | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Rof/RNase P subunit-like | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| OMPT-like | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Phospholipase C/P1 nuclease | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| AbfB domain | 0 | DIRECT |
| Putative isomerase YbhE | 0 | DIRECT |
| Cellulose docking domain, dockering | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| EGF/Laminin | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
| RNase A-like | 0 | DIRECT |
| HybD-like | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| Replicase NSP9 | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Carbohydrate binding domain | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| (Trans)glycosidases | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| Toprim domain | 0 | DIRECT |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Rnp2-like | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Type X cellulose binding domain, CBDX | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Type I dockerin domain | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| Nucleoside hydrolase | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
| alpha/beta-Hydrolases | 0 | DIRECT |
| Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| Viral protein domain | 0 | DIRECT |
| NSP3A-like | 0 | DIRECT |
| Anthrax protective antigen | 0 | DIRECT |
| Dextranase, N-terminal domain | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Peptidyl-tRNA hydrolase domain-like | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| STI-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| Acylphosphatase/BLUF domain-like | 0 | DIRECT |
| Ribonuclease Rh-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Penicillin-binding protein associated domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Galactose-binding domain-like | 0 | DIRECT |
| DNA primase core | 0 | DIRECT |
| Peptidyl-tRNA hydrolase-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| LD-carboxypeptidase A C-terminal domain-like | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Collagen-binding domain | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| beta-N-acetylhexosaminidase-like domain | 0 | DIRECT |
| Aminopeptidase/glucanase lid domain | 0 | DIRECT |
| TMV-like viral coat proteins | 0 | DIRECT |
| Glycosyl hydrolases family 6, cellulases | 0 | DIRECT |
| Microbial ribonucleases | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| Arabinanase/levansucrase/invertase | 0 | DIRECT |
| Ribosome inactivating proteins (RIP) | 0 | DIRECT |
| Thermostable phytase (3-phytase) | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Phage fibre proteins | 0 | DIRECT |
| SARS Nsp1-like | 0 | DIRECT |
| XseB-like | 0 | DIRECT |
| ComB-like | 0 | DIRECT |
| Peptidyl-tRNA hydrolase II | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| Herpes virus serine proteinase, assemblin | 0 | DIRECT |
| Coronavirus NSP10-like | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Prokaryotic SH3-related domain | 0 | DIRECT |
| Phosphotyrosine protein phosphatases I | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Coronavirus NSP7-like | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| Kazal-type serine protease inhibitors | 0 | DIRECT |
| Plant lectins/antimicrobial peptides | 0 | DIRECT |
| Nitrous oxide reductase, N-terminal domain | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Cysteine proteinases | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| SurE-like | 0 | DIRECT |
| Methylesterase CheB, C-terminal domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| EF-hand | 1.756e-16 | DIRECT |
| HIT-like | 0.000000000000002433 | DIRECT |
| CYTH-like phosphatases | 0.000000000000004848 | DIRECT |
| LysM domain | 0.000000000000004848 | DIRECT |
| RING/U-box | 0.00000000000001068 | DIRECT |
| Xylose isomerase-like | 0.00000000000003187 | DIRECT |
| Calcium-dependent phosphotriesterase | 0.0000000000001808 | DIRECT |
| Sec63 N-terminal domain-like | 0.000000000002009 | DIRECT |
| Ubiquitin-like | 0.000000000043 | DIRECT |
| Purine and uridine phosphorylases | 0.000000001211 | DIRECT |
| UBA-like | 0.000000001533 | DIRECT |
| GAF domain-like | 0.000000002258 | DIRECT |
| beta-Roll | 0.000000002295 | DIRECT |
| PH domain-like | 0.000000004311 | DIRECT |
| Translation proteins | 0.00000002486 | DIRECT |
| LDL receptor-like module | 0.0000001712 | DIRECT |
| Hairpin loop containing domain-like | 0.0000001712 | DIRECT |
| HD-domain/PDEase-like | 0.0000005125 | DIRECT |
| DEATH domain | 0.0000007994 | DIRECT |
| YrdC/RibB | 0.0000009058 | DIRECT |
| Fibronectin type III | 0.000001199 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.000003541 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0.000003651 | DIRECT |
| Starch-binding domain-like | 0.000004794 | DIRECT |
| Phospholipase D/nuclease | 0.000005572 | DIRECT |
| Staphylococcal nuclease | 0.00001209 | DIRECT |
| SAP domain | 0.00001342 | DIRECT |
| EAL domain-like | 0.000031 | DIRECT |
| CBD9-like | 0.000031 | DIRECT |
| HCP-like | 0.00004767 | DIRECT |
| DEK C-terminal domain | 0.00004893 | DIRECT |
| HIT/MYND zinc finger-like | 0.00005243 | DIRECT |
| WD40 repeat-like | 0.00007669 | DIRECT |
| Phosphoglycerate mutase-like | 0.00008936 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0.0002001 | DIRECT |
| SRCR-like | 0.0002174 | DIRECT |
| Ran binding protein zinc finger-like | 0.0004288 | DIRECT |
| FnI-like domain | 0.0004288 | DIRECT |
| Tudor/PWWP/MBT | 0.0005506 | DIRECT |
| Barwin-like endoglucanases | 0.0005654 | DIRECT |
| Integrin alpha N-terminal domain | 0.002481 | INHERITED FROM: Glycosylphosphatidylinositol phospholipase D || Acting on ester bonds || Phosphoric diester hydrolases |
| Cell wall binding repeat | 0.002821 | INHERITED FROM: Glycosylases || In linear amides || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || N-acetylmuramoyl-L-alanine amidase |
| Ankyrin repeat | 0.003232 | INHERITED FROM: Glycerophosphodiester phosphodiesterase || Carboxylic ester hydrolases || Glutaminase || NAD(+) diphosphatase || In linear amides || 1-alkyl-2-acetylglycerophosphocholine esterase || Asparaginase || Acting on carbon-nitrogen bonds, other than peptid || Lysophospholipase |
| Hedgehog/intein (Hint) domain | 0.006232 | INHERITED FROM: H(+)-transporting two-sector ATPase || DNA helicase || Acting on acid anhydrides |
| Ricin B-like lectins | 0.0111 | INHERITED FROM: Alpha-galactosidase || Glycosylases || rRNA N-glycosylase |
| Ras GEF | 0.01132 | INHERITED FROM: Phosphoinositide phospholipase C || Acting on ester bonds || Phosphoric diester hydrolases |
| Homing endonucleases | 0.01293 | INHERITED FROM: H(+)-transporting two-sector ATPase || DNA helicase || Acting on acid anhydrides |
| Second domain of FERM | 0.01565 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Chromo domain-like | 0.01777 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase || Acting on acid anhydrides |
| PX domain | 0.02006 | INHERITED FROM: Phospholipase D || Acting on ester bonds || Phosphoric diester hydrolases |
| RNA-binding domain, RBD | 0.02574 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase || Exoribonucleases producing 5'-phosphomonoesters || Phosphoinositide 5-phosphatase || Poly(A)-specific ribonuclease |
| E set domains | 0.02764 | INHERITED FROM: Flavivirin || Nucleoside-triphosphatase || Acting on peptide bonds (peptide hydrolases) || Glycosylases || Acting on acid anhydrides; involved in cellular an || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || RNA helicase || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehal || In phosphorous-containing anhydrides || Acting on acid anhydrides || Pullulanase || Togavirin || Serine endopeptidases || Isoamylase |
| Chaperone J-domain | 0.02773 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| GTPase activation domain, GAP | 0.02773 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Phosphoinositide 5-phosphatase |
| MIT domain | 0.04937 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Microtubule-severing ATPase || Acting on acid anhydrides |
| Thioesterase/thiol ester dehydrase-isomerase | 0.07126 | INHERITED FROM: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase || Acting on ester bonds || Thiolester hydrolases || Choloyl-CoA hydrolase |
| TATA-box binding protein-like | 0.08744 | INHERITED FROM: DNA-3-methyladenine glycosylase II || Glycosylases || Hydrolyzing N-glycosyl compounds |
| Rhodanese/Cell cycle control phosphatase | 0.09906 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase || Omega peptidases || Phosphoprotein phosphatase || Ubiquitinyl hydrolase 1 |
| CRAL/TRIO domain | 0.1299 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-tyrosine-phosphatase |
| HSP20-like chaperones | 0.155 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 |
| FAH | 0.1932 | INHERITED FROM: Acting on carbon-carbon bonds || Fumarylacetoacetase || Acylpyruvate hydrolase |
| NTF2-like | 0.2758 | INHERITED FROM: Phosphoric monoester hydrolases || RNA helicase || Sucrose-phosphate phosphatase || Acting on ester bonds |
| ARM repeat | 0.2789 | INHERITED FROM: Ether hydrolases || Leukotriene-A(4) hydrolase || Aminopeptidase B || Omega peptidases || Acting on ether bonds || Ubiquitinyl hydrolase 1 |
| beta-sandwich domain of Sec23/24 | 0.2959 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an |
| Duplicated hybrid motif | 0.4205 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Metalloendopeptidases || Lysostaphin |
| PHP domain-like | 0.4387 | INHERITED FROM: Ribonuclease P || Acting on ester bonds || Histidinol-phosphatase || Endoribonucleases producing 5'-phosphomonoesters |
| WW domain | 0.6317 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
| Non-globular alpha+beta subunits of globular proteins | 0.6406 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-tyrosine-phosphatase |
| FYVE/PHD zinc finger | 0.6467 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on acid anhydrides; involved in cellular an || DNA helicase || Protein-tyrosine-phosphatase |
| Kelch motif | 0.774 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoprotein phosphatase |
| Bromodomain | 0.8046 | INHERITED FROM: Adenosinetriphosphatase |
| Prokaryotic type I DNA topoisomerase | 0.8563 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase || Acting on acid anhydrides |
| SMAD/FHA domain | 0.8718 | INHERITED FROM: Phosphoric monoester hydrolases |
| DNA-glycosylase | 0.9835 | INHERITED FROM: DNA-3-methyladenine glycosylase II || Glycosylases || Hydrolyzing N-glycosyl compounds |
| Growth factor receptor domain | 0.988 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Coagulation factor Xa || Furin || Serine endopeptidases |
| Quinoprotein alcohol dehydrogenase-like | 0.9965 | INHERITED FROM: Exoribonucleases producing 5'-phosphomonoesters || Poly(A)-specific ribonuclease |
| LuxS/MPP-like metallohydrolase | 0.9988 | INHERITED FROM: Mitochondrial processing peptidase || Acting on peptide bonds (peptide hydrolases) || Nardilysin || Metalloendopeptidases || Insulysin || Pitrilysin |
| Heme oxygenase-like | 1 | INHERITED FROM: Aminopyrimidine aminohydrolase || In other compounds |
| SH3-domain | 1 | INHERITED FROM: Phosphoinositide phospholipase C || Phosphoric diester hydrolases |
| SAM/Pointed domain | 1 | INHERITED FROM: Phosphatidylinositol-3,4,5-trisphosphate 5-phospha |
| L30e-like | 1 | INHERITED FROM: Ribonuclease P |
| TPR-like | 1 | INHERITED FROM: Phosphoprotein phosphatase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase || In cyclic amidines || Methenyltetrahydrofolate cyclohydrolase || Thioether and trialkylsulfonium hydrolases || Acting on carbon-nitrogen bonds, other than peptid || Acting on ether bonds || Alpha-N-acetylgalactosaminidase || Oleoyl-[acyl-carrier-protein] hydrolase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| LDH C-terminal domain-like | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase || 6-phospho-beta-glucosidase || Alpha-galactosidase || Alpha-glucosidase |
| ADC-like | 1 | INHERITED FROM: Vesicle-fusing ATPase |
| AraD/HMP-PK domain-like | 1 | INHERITED FROM: Acireductone synthase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: Polynucleotide 5'-phosphatase |
| GroES-like | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | INHERITED FROM: Trehalose-phosphatase |
| Actin-like ATPase domain | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha || Exopolyphosphatase |
| ACP-like | 1 | INHERITED FROM: Isochorismatase || Ether hydrolases || Thiolester hydrolases || Acting on ether bonds || Oleoyl-[acyl-carrier-protein] hydrolase |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | INHERITED FROM: Endodeoxyribonucleases producing 5'-phosphomonoest || Deoxyribonuclease V |
| PYP-like sensor domain (PAS domain) | 1 | INHERITED FROM: 3',5'-cyclic-nucleotide phosphodiesterase || Phosphoric diester hydrolases |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Exoribonucleases producing 5'-phosphomonoesters || Ribonuclease E || DNA helicase || Acting on acid anhydrides || Exoribonuclease II |
| Immunoglobulin | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Carbonic anhydrase | 1 | INHERITED FROM: Protein-tyrosine-phosphatase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Alkaline phosphatase || Alkylglycerophosphoethanolamine phosphodiesterase || Phosphodiesterase I || Nucleotide diphosphatase || Acting on carbon-phosphorus bonds || Sulfuric ester hydrolases || Acting on ester bonds || Phosphoric diester hydrolases || Phosphonoacetate hydrolase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: 1-aminocyclopropane-1-carboxylate deaminase || In other compounds || Acting on carbon-nitrogen bonds, other than peptid |
| L domain-like | 1 | INHERITED FROM: Exoribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Phosphoprotein phosphatase || Poly(A)-specific ribonuclease |
| CBS-domain pair | 1 | INHERITED FROM: Quaternary-amine-transporting ATPase |
| DNA clamp | 1 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoeste || Exodeoxyribonuclease III |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| DHS-like NAD/FAD-binding domain | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
| Bet v1-like | 1 | INHERITED FROM: Acetyl-CoA hydrolase || Thiolester hydrolases |
| PUA domain-like | 1 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Endopeptidase La || Serine endopeptidases |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Flavivirin || Nucleoside-triphosphatase || RNA helicase || Endothelin-converting enzyme 1 || Polynucleotide 5'-phosphatase || SARS coronavirus main proteinase || Oleoyl-[acyl-carrier-protein] hydrolase |
| ACT-like | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Formyltetrahydrofolate deformylase || Diphosphoric monoester hydrolases |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Diaminohydroxyphosphoribosylaminopyrimidine deamin || In cyclic amidines || Acting on carbon-nitrogen bonds, other than peptid |
| TGS-like | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases |
| Cupredoxins | 1 | INHERITED FROM: Protein-arginine deiminase || In linear amidines |
| PLP-dependent transferases | 1 | INHERITED FROM: Acting on carbon-carbon bonds || Kynureninase |
| PIN domain-like | 1 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoeste || Exodeoxyribonuclease (lambda-induced) |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA helicase |
| Nucleotidyltransferase | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases |
| RmlC-like cupins | 1 | INHERITED FROM: In linear amidines || Ureidoglycolate hydrolase || Acting on carbon-nitrogen bonds, other than peptid |
| Thiolase-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Dipeptidases || Dipeptidase E || Cyanophycinase || Gamma-glutamyl hydrolase || Muramoyltetrapeptide carboxypeptidase || Gamma-glutamyl-gamma-aminobutyrate hydrolase || Beta-galactosidase || Peptidyl-dipeptidases |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Ribosomal protein S5 domain 2-like | 1 | INHERITED FROM: Ribonuclease P || Acting on ester bonds || Histidinol-phosphatase || Endopeptidase La || Serine endopeptidases || Endoribonucleases producing 5'-phosphomonoesters |
| FMT C-terminal domain-like | 1 | INHERITED FROM: DNA-3-methyladenine glycosylase II |
| SH2 domain | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoinositide phospholipase C || Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric diester hydrolases || Phosphatidylinositol-3,4,5-trisphosphate 5-phospha |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| LigT-like | 0 | Direct |
| Plant invertase/pectin methylesterase inhibitor | 0 | Direct |
| PUG domain-like | 0 | Direct |
| Cellulose-binding domain | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| DNase I-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| PKD domain | 0 | Direct |
| Outer membrane phospholipase A (OMPLA) | 0 | Direct |
| Invasin/intimin cell-adhesion fragments | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| dUTPase-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| DHH phosphoesterases | 0 | Direct |
| Nudix | 0 | Direct |
| Dcp2 domain-like | 0 | Direct |
| Apyrase | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| LmbE-like | 0 | Direct |
| PP2C-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Voltage-gated potassium channels | 0 | Direct |
| Kringle-like | 0 | Direct |
| Coronavirus NSP8-like | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Influenza hemagglutinin (stalk) | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| Origin of replication-binding domain, RBD-like | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| Autotransporter | 0 | Direct |
| Sec-C motif | 0 | Direct |
| Acid proteases | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| tRNA-intron endonuclease N-terminal domain-like | 0 | Direct |
| Hyaluronidase post-catalytic domain-like | 0 | Direct |
| L9 N-domain-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| R3H domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| TRAF domain-like | 0 | Direct |
| all-alpha NTP pyrophosphatases | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| AlbA-like | 0 | Direct |
| Bacterial GAP domain | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| PGBD-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
| Pentein | 0 | Direct |
| MOP-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Holliday junction resolvase RusA | 0 | Direct |
| Carbohydrate-binding domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Saposin | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Rof/RNase P subunit-like | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| OMPT-like | 0 | Direct |
| Sialidases | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Phospholipase C/P1 nuclease | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| AbfB domain | 0 | Direct |
| Putative isomerase YbhE | 0 | Direct |
| Cellulose docking domain, dockering | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| HAD-like | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| EGF/Laminin | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
| RNase A-like | 0 | Direct |
| HybD-like | 0 | Direct |
| HisI-like | 0 | Direct |
| Replicase NSP9 | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Carbohydrate binding domain | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| (Trans)glycosidases | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| Toprim domain | 0 | Direct |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Rnp2-like | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Type X cellulose binding domain, CBDX | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Type I dockerin domain | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| Nucleoside hydrolase | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| beta-Galactosidase/glucuronidase domain | 0 | Direct |
| alpha/beta-Hydrolases | 0 | Direct |
| Beta-galactosidase LacA, domain 3 | 0 | Direct |
| GLA-domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| (Phosphotyrosine protein) phosphatases II | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| Viral protein domain | 0 | Direct |
| NSP3A-like | 0 | Direct |
| Anthrax protective antigen | 0 | Direct |
| Dextranase, N-terminal domain | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| ITPase-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Peptidyl-tRNA hydrolase domain-like | 0 | Direct |
| Putative cyclase | 0 | Direct |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| STI-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| PA domain | 0 | Direct |
| Creatininase | 0 | Direct |
| Caspase-like | 0 | Direct |
| Acylphosphatase/BLUF domain-like | 0 | Direct |
| Ribonuclease Rh-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| EndoU-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Penicillin-binding protein associated domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Galactose-binding domain-like | 0 | Direct |
| DNA primase core | 0 | Direct |
| Peptidyl-tRNA hydrolase-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Trefoil | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| LD-carboxypeptidase A C-terminal domain-like | 0 | Direct |
| RibA-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Collagen-binding domain | 0 | Direct |
| HRDC-like | 0 | Direct |
| vWA-like | 0 | Direct |
| D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| beta-N-acetylhexosaminidase-like domain | 0 | Direct |
| Aminopeptidase/glucanase lid domain | 0 | Direct |
| TMV-like viral coat proteins | 0 | Direct |
| Glycosyl hydrolases family 6, cellulases | 0 | Direct |
| Microbial ribonucleases | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| Arabinanase/levansucrase/invertase | 0 | Direct |
| Ribosome inactivating proteins (RIP) | 0 | Direct |
| Thermostable phytase (3-phytase) | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Phage fibre proteins | 0 | Direct |
| SARS Nsp1-like | 0 | Direct |
| XseB-like | 0 | Direct |
| ComB-like | 0 | Direct |
| Peptidyl-tRNA hydrolase II | 0 | Direct |
| SEA domain | 0 | Direct |
| Herpes virus serine proteinase, assemblin | 0 | Direct |
| Coronavirus NSP10-like | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Prokaryotic SH3-related domain | 0 | Direct |
| Phosphotyrosine protein phosphatases I | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Coronavirus NSP7-like | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| Kazal-type serine protease inhibitors | 0 | Direct |
| Plant lectins/antimicrobial peptides | 0 | Direct |
| Nitrous oxide reductase, N-terminal domain | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Cysteine proteinases | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| SurE-like | 0 | Direct |
| Methylesterase CheB, C-terminal domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| CheY-like | 0 | Direct |
| EF-hand | 1.756e-16 | Direct |
| HIT-like | 0.000000000000002433 | Direct |
| CYTH-like phosphatases | 0.000000000000004848 | Direct |
| LysM domain | 0.000000000000004848 | Direct |
| RING/U-box | 0.00000000000001068 | Direct |
| Xylose isomerase-like | 0.00000000000003187 | Direct |
| Calcium-dependent phosphotriesterase | 0.0000000000001808 | Direct |
| Sec63 N-terminal domain-like | 0.000000000002009 | Direct |
| Ubiquitin-like | 0.000000000043 | Direct |
| Purine and uridine phosphorylases | 0.000000001211 | Direct |
| UBA-like | 0.000000001533 | Direct |
| GAF domain-like | 0.000000002258 | Direct |
| beta-Roll | 0.000000002295 | Direct |
| PH domain-like | 0.000000004311 | Direct |
| Translation proteins | 0.00000002486 | Direct |
| LDL receptor-like module | 0.0000001712 | Direct |
| Hairpin loop containing domain-like | 0.0000001712 | Direct |
| HD-domain/PDEase-like | 0.0000005125 | Direct |
| DEATH domain | 0.0000007994 | Direct |
| YrdC/RibB | 0.0000009058 | Direct |
| Fibronectin type III | 0.000001199 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.000003541 | Direct |
| N-(deoxy)ribosyltransferase-like | 0.000003651 | Direct |
| Starch-binding domain-like | 0.000004794 | Direct |
| Phospholipase D/nuclease | 0.000005572 | Direct |
| Staphylococcal nuclease | 0.00001209 | Direct |
| SAP domain | 0.00001342 | Direct |
| EAL domain-like | 0.000031 | Direct |
| CBD9-like | 0.000031 | Direct |
| HCP-like | 0.00004767 | Direct |
| DEK C-terminal domain | 0.00004893 | Direct |
| HIT/MYND zinc finger-like | 0.00005243 | Direct |
| WD40 repeat-like | 0.00007669 | Direct |
| Phosphoglycerate mutase-like | 0.00008936 | Direct |
| NagB/RpiA/CoA transferase-like | 0.0002001 | Direct |
| SRCR-like | 0.0002174 | Direct |
| Ran binding protein zinc finger-like | 0.0004288 | Direct |
| FnI-like domain | 0.0004288 | Direct |
| Tudor/PWWP/MBT | 0.0005506 | Direct |
| Barwin-like endoglucanases | 0.0005654 | Direct |
| Integrin alpha N-terminal domain | 0.002481 | Inherited |
| Cell wall binding repeat | 0.002821 | Inherited |
| Ankyrin repeat | 0.003232 | Inherited |
| Hedgehog/intein (Hint) domain | 0.006232 | Inherited |
| Ricin B-like lectins | 0.0111 | Inherited |
| Ras GEF | 0.01132 | Inherited |
| Homing endonucleases | 0.01293 | Inherited |
| Second domain of FERM | 0.01565 | Inherited |
| Chromo domain-like | 0.01777 | Inherited |
| PX domain | 0.02006 | Inherited |
| RNA-binding domain, RBD | 0.02574 | Inherited |
| E set domains | 0.02764 | Inherited |
| Chaperone J-domain | 0.02773 | Inherited |
| GTPase activation domain, GAP | 0.02773 | Inherited |
| MIT domain | 0.04937 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 0.07126 | Inherited |
| TATA-box binding protein-like | 0.08744 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.09906 | Inherited |
| CRAL/TRIO domain | 0.1299 | Inherited |
| HSP20-like chaperones | 0.155 | Inherited |
| FAH | 0.1932 | Inherited |
| NTF2-like | 0.2758 | Inherited |
| ARM repeat | 0.2789 | Inherited |
| beta-sandwich domain of Sec23/24 | 0.2959 | Inherited |
| Duplicated hybrid motif | 0.4205 | Inherited |
| PHP domain-like | 0.4387 | Inherited |
| WW domain | 0.6317 | Inherited |
| Non-globular alpha+beta subunits of globular proteins | 0.6406 | Inherited |
| FYVE/PHD zinc finger | 0.6467 | Inherited |
| Kelch motif | 0.774 | Inherited |
| Bromodomain | 0.8046 | Inherited |
| Prokaryotic type I DNA topoisomerase | 0.8563 | Inherited |
| SMAD/FHA domain | 0.8718 | Inherited |
| DNA-glycosylase | 0.9835 | Inherited |
| Growth factor receptor domain | 0.988 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.9965 | Inherited |
| LuxS/MPP-like metallohydrolase | 0.9988 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| SAM/Pointed domain | 1 | Inherited |
| L30e-like | 1 | Inherited |
| TPR-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| LDH C-terminal domain-like | 1 | Inherited |
| ADC-like | 1 | Inherited |
| AraD/HMP-PK domain-like | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| GroES-like | 1 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | Inherited |
| Actin-like ATPase domain | 1 | Inherited |
| ACP-like | 1 | Inherited |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | Inherited |
| PYP-like sensor domain (PAS domain) | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| Carbonic anhydrase | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| L domain-like | 1 | Inherited |
| CBS-domain pair | 1 | Inherited |
| DNA clamp | 1 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
| DHS-like NAD/FAD-binding domain | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| PUA domain-like | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| ACT-like | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Cupredoxins | 1 | Inherited |
| PLP-dependent transferases | 1 | Inherited |
| PIN domain-like | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| Nucleotidyltransferase | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| Thiolase-like | 1 | Inherited |
| Class I glutamine amidotransferase-like | 1 | Inherited |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Ribosomal protein S5 domain 2-like | 1 | Inherited |
| FMT C-terminal domain-like | 1 | Inherited |
| SH2 domain | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (Not in SPEO)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
82708,53098
82708 - R3H domain
53098 - Ribonuclease H-like | 0 | DIRECT |
49384,55545
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain | 0 | DIRECT |
47090,47090
47090 - PGBD-like
47090 - PGBD-like | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49785,49303
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
100939,68906
100939 - SPOC domain-like
68906 - SAP domain | 0 | DIRECT |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56219,54928
56219 - DNase I-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
56784,54427
56784 - HAD-like
54427 - NTF2-like | 0 | DIRECT |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
52540,54928
52540 - P-loop containing nucleoside triphosphate hydrolases
54928 - RNA-binding domain, RBD | 0 | DIRECT |
50156,52799
50156 - PDZ domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
49464,53187
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
117100,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | DIRECT |
57184,50494
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
50249,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
51011,49265
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | DIRECT |
52540,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
56784,53474
56784 - HAD-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
51278,51338
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
160481,160481
160481 - BRK domain-like
160481 - BRK domain-like | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57630,57440
57630 - GLA-domain
57440 - Kringle-like | 0 | DIRECT |
49562,52151
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
52279,56988
52279 - Beta-D-glucan exohydrolase, C-terminal domain
56988 - Anthrax protective antigen | 0 | DIRECT |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0 | DIRECT |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
48452,56300
48452 - TPR-like
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
56601,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
158702,81296
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
54001,53098
54001 - Cysteine proteinases
53098 - Ribonuclease H-like | 0 | DIRECT |
52540,55144
52540 - P-loop containing nucleoside triphosphate hydrolases
55144 - LigT-like | 0 | DIRECT |
51283,51283
51283 - dUTPase-like
51283 - dUTPase-like | 0 | DIRECT |
54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | DIRECT |
81324,52799
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
48208,49452
48208 - Six-hairpin glycosidases
49452 - Starch-binding domain-like | 0 | DIRECT |
53067,109604
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | DIRECT |
81653,81665
81653 - Calcium ATPase, transduction domain A
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
48537,49723
48537 - Phospholipase C/P1 nuclease
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
140657,49785
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
57630,57184
57630 - GLA-domain
57184 - Growth factor receptor domain | 0 | DIRECT |
49384,51445
49384 - Carbohydrate-binding domain
51445 - (Trans)glycosidases | 0 | DIRECT |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | DIRECT |
50916,46785
50916 - Rap30/74 interaction domains
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57180,51445
57180 - Cellulose-binding domain
51445 - (Trans)glycosidases | 0 | DIRECT |
51445,81296
51445 - (Trans)glycosidases
81296 - E set domains | 0 | DIRECT |
56784,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
47473,144091
47473 - EF-hand
144091 - Rhomboid-like | 0 | DIRECT |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
53092,55920
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | DIRECT |
51011,51445
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases | 0 | DIRECT |
49384,57615
49384 - Carbohydrate-binding domain
57615 - Type X cellulose binding domain, CBDX | 0 | DIRECT |
57424,49854
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
48371,54001
48371 - ARM repeat
54001 - Cysteine proteinases | 0 | DIRECT |
49344,49344
49344 - CBD9-like
49344 - CBD9-like | 0 | DIRECT |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | DIRECT |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
101821,53187
101821 - Aminopeptidase/glucanase lid domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | DIRECT |
64571,64571
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
103642,55920
103642 - Sec-C motif
55920 - Creatinase/aminopeptidase | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54111,51278
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit | 0 | DIRECT |
56371,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins | 0 | DIRECT |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | DIRECT |
49265,49384
49265 - Fibronectin type III
49384 - Carbohydrate-binding domain | 0 | DIRECT |
52540,57756
52540 - P-loop containing nucleoside triphosphate hydrolases
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
55811,55811
55811 - Nudix
55811 - Nudix | 0 | DIRECT |
101908,56219
101908 - Putative isomerase YbhE
56219 - DNase I-like | 0 | DIRECT |
52949,53187
52949 - Macro domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
52266,49818
52266 - SGNH hydrolase
49818 - Viral protein domain | 0 | DIRECT |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
49562,56024
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56024 - Phospholipase D/nuclease | 0 | DIRECT |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
54403,54001
54403 - Cystatin/monellin
54001 - Cysteine proteinases | 0 | DIRECT |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
56784,56784
56784 - HAD-like
56784 - HAD-like | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
47233,52799
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
100939,101420
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | DIRECT |
49854,49899
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
74924,54001
74924 - Cap-Gly domain
54001 - Cysteine proteinases | 0 | DIRECT |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
101596,51126
101596 - Dextranase, N-terminal domain
51126 - Pectin lyase-like | 0 | DIRECT |
54106,54001
54106 - LysM domain
54001 - Cysteine proteinases | 0 | DIRECT |
46785,47819
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | DIRECT |
56601,52091
56601 - beta-lactamase/transpeptidase-like
52091 - SpoIIaa-like | 0 | DIRECT |
58091,49899
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
49899,50386
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | DIRECT |
52540,54211
52540 - P-loop containing nucleoside triphosphate hydrolases
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
56731,52540
56731 - DNA primase core
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
55545,51445
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | DIRECT |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
55608,52540
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55821,142695
55821 - YrdC/RibB
142695 - RibA-like | 0 | DIRECT |
55658,53098
55658 - L9 N-domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
47819,47819
47819 - HRDC-like
47819 - HRDC-like | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
158702,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51445,63446
51445 - (Trans)glycosidases
63446 - Type I dockerin domain | 0 | DIRECT |
51445,52317
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like | 0 | DIRECT |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
75005,49899
75005 - Arabinanase/levansucrase/invertase
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
48024,52540
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49452,52799
49452 - Starch-binding domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
52768,52768
52768 - Arginase/deacetylase
52768 - Arginase/deacetylase | 0 | DIRECT |
51445,52279
51445 - (Trans)glycosidases
52279 - Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
51695,51695
51695 - PLC-like phosphodiesterases
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53927,53597
53927 - Cytidine deaminase-like
53597 - Dihydrofolate reductase-like | 0 | DIRECT |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57850,54001
57850 - RING/U-box
54001 - Cysteine proteinases | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
57016,53955
57016 - Plant lectins/antimicrobial peptides
53955 - Lysozyme-like | 0 | DIRECT |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | DIRECT |
52058,56219
52058 - L domain-like
56219 - DNase I-like | 0 | DIRECT |
140586,55811
140586 - Dcp2 domain-like
55811 - Nudix | 0 | DIRECT |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
51445,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
101386,101386
101386 - all-alpha NTP pyrophosphatases
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
81665,81660
81665 - Calcium ATPase, transmembrane domain M
81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48208,49384
48208 - Six-hairpin glycosidases
49384 - Carbohydrate-binding domain | 0 | DIRECT |
49303,74650
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57535,53300
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | DIRECT |
52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | DIRECT |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
55021,53328
55021 - ACT-like
53328 - Formyltransferase | 0 | DIRECT |
46946,57716
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55486,49899
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
54001,46934
54001 - Cysteine proteinases
46934 - UBA-like | 0 | DIRECT |
53639,56784
53639 - AraD/HMP-PK domain-like
56784 - HAD-like | 0 | DIRECT |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0 | DIRECT |
63433,56529
63433 - Fumarylacetoacetate hydrolase, FAH, N-terminal domain
56529 - FAH | 0 | DIRECT |
55486,51120
55486 - Metalloproteases ("zincins"), catalytic domain
51120 - beta-Roll | 0 | DIRECT |
52317,51011
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | DIRECT |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
51069,49265
51069 - Carbonic anhydrase
49265 - Fibronectin type III | 0 | DIRECT |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
101148,51126
101148 - Plant invertase/pectin methylesterase inhibitor
51126 - Pectin lyase-like | 0 | DIRECT |
55267,53032
55267 - tRNA-intron endonuclease N-terminal domain-like
53032 - tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
47781,46929
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
56601,69189
56601 - beta-lactamase/transpeptidase-like
69189 - Penicillin-binding protein associated domain | 0 | DIRECT |
49785,63446
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | DIRECT |
81624,46946
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain | 0 | DIRECT |
49265,49452
49265 - Fibronectin type III
49452 - Starch-binding domain-like | 0 | DIRECT |
50370,50370
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | DIRECT |
49303,49303
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
50156,52096
50156 - PDZ domain-like
52096 - ClpP/crotonase | 0 | DIRECT |
52151,52151
52151 - FabD/lysophospholipase-like
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
51445,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
82671,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
52172,52738
52172 - CheY-like
52738 - Methylesterase CheB, C-terminal domain | 0 | DIRECT |
51294,52540
51294 - Hedgehog/intein (Hint) domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48208,63446
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | DIRECT |
50044,51695
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53032,55267
53032 - tRNA-intron endonuclease catalytic domain-like
55267 - tRNA-intron endonuclease N-terminal domain-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
51445,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like | 0 | DIRECT |
50974,50974
50974 - Nitrous oxide reductase, N-terminal domain
50974 - Nitrous oxide reductase, N-terminal domain | 0 | DIRECT |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
53774,48403
53774 - Glutaminase/Asparaginase
48403 - Ankyrin repeat | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
110296,110296
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
53300,100939
53300 - vWA-like
100939 - SPOC domain-like | 0 | DIRECT |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
81761,53474
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
52266,103515
52266 - SGNH hydrolase
103515 - Autotransporter | 0 | DIRECT |
53300,50494
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54001,144232
54001 - Cysteine proteinases
144232 - HIT/MYND zinc finger-like | 0 | DIRECT |
81296,48208
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | DIRECT |
55846,47090
55846 - N-acetylmuramoyl-L-alanine amidase-like
47090 - PGBD-like | 0 | DIRECT |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
52087,52799
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
102860,54197
102860 - mRNA decapping enzyme DcpS N-terminal domain
54197 - HIT-like | 0 | DIRECT |
52317,141986
52317 - Class I glutamine amidotransferase-like
141986 - LD-carboxypeptidase A C-terminal domain-like | 0 | DIRECT |
51011,117100
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
50331,50331
50331 - MOP-like
50331 - MOP-like | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
49854,50494
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
49899,49854
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53649,54060
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | DIRECT |
54980,54980
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49384,49265
49384 - Carbohydrate-binding domain
49265 - Fibronectin type III | 0 | DIRECT |
55464,52540
55464 - Origin of replication-binding domain, RBD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,50331
52540 - P-loop containing nucleoside triphosphate hydrolases
50331 - MOP-like | 0 | DIRECT |
49854,82895
49854 - Spermadhesin, CUB domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
69065,69065
69065 - RNase III domain-like
69065 - RNase III domain-like | 0 | DIRECT |
55550,52799
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | DIRECT |
55486,58091
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
75001,54001
75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
54001 - Cysteine proteinases | 0 | DIRECT |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
54001,49785
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | DIRECT |
56300,47473
56300 - Metallo-dependent phosphatases
47473 - EF-hand | 0 | DIRECT |
53474,49785
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49899,49785
49899 - Concanavalin A-like lectins/glucanases
49785 - Galactose-binding domain-like | 0 | DIRECT |
82671,57424
82671 - SEA domain
57424 - LDL receptor-like module | 0 | DIRECT |
100895,56487
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like | 0 | DIRECT |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
50886,50886
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
52499,47336
52499 - Isochorismatase-like hydrolases
47336 - ACP-like | 0 | DIRECT |
51445,49344
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | DIRECT |
49265,51445
49265 - Fibronectin type III
51445 - (Trans)glycosidases | 0 | DIRECT |
56300,56300
56300 - Metallo-dependent phosphatases
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
51011,50370
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | DIRECT |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81665,56784
81665 - Calcium ATPase, transmembrane domain M
56784 - HAD-like | 0 | DIRECT |
52540,49899
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
53098,47819
53098 - Ribonuclease H-like
47819 - HRDC-like | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
49899,110221
49899 - Concanavalin A-like lectins/glucanases
110221 - AbfB domain | 0 | DIRECT |
56487,57424
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | DIRECT |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | DIRECT |
143503,54001
143503 - PUG domain-like
54001 - Cysteine proteinases | 0 | DIRECT |
51445,51055
51445 - (Trans)glycosidases
51055 - Carbohydrate binding domain | 0 | DIRECT |
51445,49384
51445 - (Trans)glycosidases
49384 - Carbohydrate-binding domain | 0 | DIRECT |
52540,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
53955,54106
53955 - Lysozyme-like
54106 - LysM domain | 0 | DIRECT |
50729,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
49303,51445
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | DIRECT |
51445,140657
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
55608,56712
55608 - Homing endonucleases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
54236,56784
54236 - Ubiquitin-like
56784 - HAD-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
55486,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | DIRECT |
53092,53092
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain | 0 | DIRECT |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57440,57196
57440 - Kringle-like
57196 - EGF/Laminin | 0 | DIRECT |
46785,51306
46785 - "Winged helix" DNA-binding domain
51306 - LexA/Signal peptidase | 0 | DIRECT |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
49562,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
54236,54001
54236 - Ubiquitin-like
54001 - Cysteine proteinases | 0 | DIRECT |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0 | DIRECT |
143791,143791
143791 - DUSP-like
143791 - DUSP-like | 0 | DIRECT |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
52540,54631
52540 - P-loop containing nucleoside triphosphate hydrolases
54631 - CBS-domain pair | 0 | DIRECT |
56300,55816
56300 - Metallo-dependent phosphatases
55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
49899,49599
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | DIRECT |
49785,51445
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | DIRECT |
109715,52799
109715 - DEK C-terminal domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
52743,52025
52743 - Subtilisin-like
52025 - PA domain | 0 | DIRECT |
55008,55008
55008 - HMA, heavy metal-associated domain
55008 - HMA, heavy metal-associated domain | 0 | DIRECT |
49599,54001
49599 - TRAF domain-like
54001 - Cysteine proteinases | 0 | DIRECT |
56568,47233
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain | 0 | DIRECT |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
57424,50494
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0.000000000000002606 | DIRECT |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0.000000000000004848 | DIRECT |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0.0000000000001924 | DIRECT |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.000000000004359 | DIRECT |
54106,54106
54106 - LysM domain
54106 - LysM domain | 0.00000000004095 | DIRECT |
51735,52283
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.0000000001846 | DIRECT |
88688,74650
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.0000000005406 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0.00000007599 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.0000007028 | DIRECT |
64268,50729
64268 - PX domain
50729 - PH domain-like | 0.00000154 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.000003651 | DIRECT |
51294,55608
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.000009579 | DIRECT |
51011,49452
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.000031 | DIRECT |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00004893 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.00005402 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0.0003174 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0004493 | DIRECT |
49899,50939
49899 - Concanavalin A-like lectins/glucanases
50939 - Sialidases | 0.0006227 | DIRECT |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.0007728 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0007728 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.001811 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.002481 | INHERITED FROM: Dihydroorotase || In cyclic amides || Acting on carbon-nitrogen bonds, other than peptid |
56712,51294
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0.002794 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || DNA helicase || Acting on acid anhydrides |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.002794 | INHERITED FROM: Phosphoinositide phospholipase C || Acting on ester bonds || Phosphoric diester hydrolases |
49785,81296
49785 - Galactose-binding domain-like
81296 - E set domains | 0.002995 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.009358 | INHERITED FROM: Acetyl-CoA hydrolase || Acting on ester bonds || Thiolester hydrolases |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.01132 | INHERITED FROM: Carboxylic ester hydrolases || Carboxylesterase || Acting on ester bonds |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0.01132 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Omega peptidases || Ubiquitinyl hydrolase 1 |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.01713 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.02773 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.03502 | INHERITED FROM: Dihydroorotase || In cyclic amides || Acting on carbon-nitrogen bonds, other than peptid |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.06229 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
55945,48150
55945 - TATA-box binding protein-like
48150 - DNA-glycosylase | 0.08744 | INHERITED FROM: DNA-3-methyladenine glycosylase II || Glycosylases || Hydrolyzing N-glycosyl compounds |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.389 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.5557 | INHERITED FROM: Phosphoric monoester hydrolases || Trehalose-phosphatase |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.6193 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0.6541 | INHERITED FROM: Phospholipase D || Acting on ester bonds || Phosphoric diester hydrolases |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.6958 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphoprotein phosphatase |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.7388 | INHERITED FROM: Acting on peptide bonds (peptide hydrolases) || Furin || Serine endopeptidases |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha || Exopolyphosphatase |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | INHERITED FROM: Polynucleotide 5'-phosphatase |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-tyrosine-phosphatase |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 1 | INHERITED FROM: Ribonuclease H || Endoribonucleases producing 5'-phosphomonoesters |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase || 6-phospho-beta-glucosidase || Alpha-galactosidase || Alpha-glucosidase |
54211,54211
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Histidinol-phosphatase |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 1 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehal || Pullulanase || Isoamylase |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
82708,53098
82708 - R3H domain
53098 - Ribonuclease H-like | 0 | Direct |
49384,55545
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain | 0 | Direct |
47090,47090
47090 - PGBD-like
47090 - PGBD-like | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
49785,49303
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
100939,68906
100939 - SPOC domain-like
68906 - SAP domain | 0 | Direct |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56219,54928
56219 - DNase I-like
54928 - RNA-binding domain, RBD | 0 | Direct |
56784,54427
56784 - HAD-like
54427 - NTF2-like | 0 | Direct |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
52540,54928
52540 - P-loop containing nucleoside triphosphate hydrolases
54928 - RNA-binding domain, RBD | 0 | Direct |
50156,52799
50156 - PDZ domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
49464,53187
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
117100,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | Direct |
57184,50494
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | Direct |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
50249,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
51011,49265
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | Direct |
52540,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
56784,53474
56784 - HAD-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
51278,51338
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
160481,160481
160481 - BRK domain-like
160481 - BRK domain-like | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57630,57440
57630 - GLA-domain
57440 - Kringle-like | 0 | Direct |
49562,52151
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
52151 - FabD/lysophospholipase-like | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
52279,56988
52279 - Beta-D-glucan exohydrolase, C-terminal domain
56988 - Anthrax protective antigen | 0 | Direct |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0 | Direct |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
48452,56300
48452 - TPR-like
56300 - Metallo-dependent phosphatases | 0 | Direct |
56601,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
158702,81296
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
54001,53098
54001 - Cysteine proteinases
53098 - Ribonuclease H-like | 0 | Direct |
52540,55144
52540 - P-loop containing nucleoside triphosphate hydrolases
55144 - LigT-like | 0 | Direct |
51283,51283
51283 - dUTPase-like
51283 - dUTPase-like | 0 | Direct |
54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | Direct |
81324,52799
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
48208,49452
48208 - Six-hairpin glycosidases
49452 - Starch-binding domain-like | 0 | Direct |
53067,109604
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | Direct |
81653,81665
81653 - Calcium ATPase, transduction domain A
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
48537,49723
48537 - Phospholipase C/P1 nuclease
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
140657,49785
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
57630,57184
57630 - GLA-domain
57184 - Growth factor receptor domain | 0 | Direct |
49384,51445
49384 - Carbohydrate-binding domain
51445 - (Trans)glycosidases | 0 | Direct |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | Direct |
50916,46785
50916 - Rap30/74 interaction domains
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57180,51445
57180 - Cellulose-binding domain
51445 - (Trans)glycosidases | 0 | Direct |
51445,81296
51445 - (Trans)glycosidases
81296 - E set domains | 0 | Direct |
56784,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
47473,144091
47473 - EF-hand
144091 - Rhomboid-like | 0 | Direct |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
53092,55920
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | Direct |
51011,51445
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases | 0 | Direct |
49384,57615
49384 - Carbohydrate-binding domain
57615 - Type X cellulose binding domain, CBDX | 0 | Direct |
57424,49854
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | Direct |
48371,54001
48371 - ARM repeat
54001 - Cysteine proteinases | 0 | Direct |
49344,49344
49344 - CBD9-like
49344 - CBD9-like | 0 | Direct |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | Direct |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
101821,53187
101821 - Aminopeptidase/glucanase lid domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | Direct |
64571,64571
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
103642,55920
103642 - Sec-C motif
55920 - Creatinase/aminopeptidase | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54111,51278
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit | 0 | Direct |
56371,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins | 0 | Direct |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | Direct |
49265,49384
49265 - Fibronectin type III
49384 - Carbohydrate-binding domain | 0 | Direct |
52540,57756
52540 - P-loop containing nucleoside triphosphate hydrolases
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
55811,55811
55811 - Nudix
55811 - Nudix | 0 | Direct |
101908,56219
101908 - Putative isomerase YbhE
56219 - DNase I-like | 0 | Direct |
52949,53187
52949 - Macro domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
52266,49818
52266 - SGNH hydrolase
49818 - Viral protein domain | 0 | Direct |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
49562,56024
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56024 - Phospholipase D/nuclease | 0 | Direct |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
54403,54001
54403 - Cystatin/monellin
54001 - Cysteine proteinases | 0 | Direct |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
56784,56784
56784 - HAD-like
56784 - HAD-like | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
47233,52799
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
100939,101420
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | Direct |
49854,49899
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
74924,54001
74924 - Cap-Gly domain
54001 - Cysteine proteinases | 0 | Direct |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
101596,51126
101596 - Dextranase, N-terminal domain
51126 - Pectin lyase-like | 0 | Direct |
54106,54001
54106 - LysM domain
54001 - Cysteine proteinases | 0 | Direct |
46785,47819
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | Direct |
56601,52091
56601 - beta-lactamase/transpeptidase-like
52091 - SpoIIaa-like | 0 | Direct |
58091,49899
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
49899,50386
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | Direct |
52540,54211
52540 - P-loop containing nucleoside triphosphate hydrolases
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
56731,52540
56731 - DNA primase core
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
55545,51445
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | Direct |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
55608,52540
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
55821,142695
55821 - YrdC/RibB
142695 - RibA-like | 0 | Direct |
55658,53098
55658 - L9 N-domain-like
53098 - Ribonuclease H-like | 0 | Direct |
47819,47819
47819 - HRDC-like
47819 - HRDC-like | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
158702,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51445,63446
51445 - (Trans)glycosidases
63446 - Type I dockerin domain | 0 | Direct |
51445,52317
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like | 0 | Direct |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
75005,49899
75005 - Arabinanase/levansucrase/invertase
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | Direct |
48024,52540
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49452,52799
49452 - Starch-binding domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
52768,52768
52768 - Arginase/deacetylase
52768 - Arginase/deacetylase | 0 | Direct |
51445,52279
51445 - (Trans)glycosidases
52279 - Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
51695,51695
51695 - PLC-like phosphodiesterases
51695 - PLC-like phosphodiesterases | 0 | Direct |
53927,53597
53927 - Cytidine deaminase-like
53597 - Dihydrofolate reductase-like | 0 | Direct |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57850,54001
57850 - RING/U-box
54001 - Cysteine proteinases | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
57016,53955
57016 - Plant lectins/antimicrobial peptides
53955 - Lysozyme-like | 0 | Direct |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | Direct |
52058,56219
52058 - L domain-like
56219 - DNase I-like | 0 | Direct |
140586,55811
140586 - Dcp2 domain-like
55811 - Nudix | 0 | Direct |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
51445,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | Direct |
101386,101386
101386 - all-alpha NTP pyrophosphatases
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
81665,81660
81665 - Calcium ATPase, transmembrane domain M
81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
48208,49384
48208 - Six-hairpin glycosidases
49384 - Carbohydrate-binding domain | 0 | Direct |
49303,74650
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57535,53300
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | Direct |
52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | Direct |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
55021,53328
55021 - ACT-like
53328 - Formyltransferase | 0 | Direct |
46946,57716
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | Direct |
55486,49899
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
54001,46934
54001 - Cysteine proteinases
46934 - UBA-like | 0 | Direct |
53639,56784
53639 - AraD/HMP-PK domain-like
56784 - HAD-like | 0 | Direct |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0 | Direct |
63433,56529
63433 - Fumarylacetoacetate hydrolase, FAH, N-terminal domain
56529 - FAH | 0 | Direct |
55486,51120
55486 - Metalloproteases ("zincins"), catalytic domain
51120 - beta-Roll | 0 | Direct |
52317,51011
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | Direct |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | Direct |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | Direct |
51069,49265
51069 - Carbonic anhydrase
49265 - Fibronectin type III | 0 | Direct |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
101148,51126
101148 - Plant invertase/pectin methylesterase inhibitor
51126 - Pectin lyase-like | 0 | Direct |
55267,53032
55267 - tRNA-intron endonuclease N-terminal domain-like
53032 - tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
47781,46929
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
56601,69189
56601 - beta-lactamase/transpeptidase-like
69189 - Penicillin-binding protein associated domain | 0 | Direct |
49785,63446
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | Direct |
81624,46946
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain | 0 | Direct |
49265,49452
49265 - Fibronectin type III
49452 - Starch-binding domain-like | 0 | Direct |
50370,50370
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | Direct |
49303,49303
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
50156,52096
50156 - PDZ domain-like
52096 - ClpP/crotonase | 0 | Direct |
52151,52151
52151 - FabD/lysophospholipase-like
52151 - FabD/lysophospholipase-like | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
51445,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
82671,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
52172,52738
52172 - CheY-like
52738 - Methylesterase CheB, C-terminal domain | 0 | Direct |
51294,52540
51294 - Hedgehog/intein (Hint) domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48208,63446
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | Direct |
50044,51695
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | Direct |
53032,55267
53032 - tRNA-intron endonuclease catalytic domain-like
55267 - tRNA-intron endonuclease N-terminal domain-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
51445,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like | 0 | Direct |
50974,50974
50974 - Nitrous oxide reductase, N-terminal domain
50974 - Nitrous oxide reductase, N-terminal domain | 0 | Direct |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
53774,48403
53774 - Glutaminase/Asparaginase
48403 - Ankyrin repeat | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
110296,110296
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
53300,100939
53300 - vWA-like
100939 - SPOC domain-like | 0 | Direct |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
81761,53474
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
52266,103515
52266 - SGNH hydrolase
103515 - Autotransporter | 0 | Direct |
53300,50494
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54001,144232
54001 - Cysteine proteinases
144232 - HIT/MYND zinc finger-like | 0 | Direct |
81296,48208
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | Direct |
55846,47090
55846 - N-acetylmuramoyl-L-alanine amidase-like
47090 - PGBD-like | 0 | Direct |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
52087,52799
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
102860,54197
102860 - mRNA decapping enzyme DcpS N-terminal domain
54197 - HIT-like | 0 | Direct |
52317,141986
52317 - Class I glutamine amidotransferase-like
141986 - LD-carboxypeptidase A C-terminal domain-like | 0 | Direct |
51011,117100
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | Direct |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
50331,50331
50331 - MOP-like
50331 - MOP-like | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
49854,50494
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | Direct |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
49899,49854
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | Direct |
53649,54060
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | Direct |
54980,54980
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
49384,49265
49384 - Carbohydrate-binding domain
49265 - Fibronectin type III | 0 | Direct |
55464,52540
55464 - Origin of replication-binding domain, RBD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,50331
52540 - P-loop containing nucleoside triphosphate hydrolases
50331 - MOP-like | 0 | Direct |
49854,82895
49854 - Spermadhesin, CUB domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
69065,69065
69065 - RNase III domain-like
69065 - RNase III domain-like | 0 | Direct |
55550,52799
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | Direct |
55486,58091
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
75001,54001
75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
54001 - Cysteine proteinases | 0 | Direct |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
54001,49785
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | Direct |
56300,47473
56300 - Metallo-dependent phosphatases
47473 - EF-hand | 0 | Direct |
53474,49785
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
49899,49785
49899 - Concanavalin A-like lectins/glucanases
49785 - Galactose-binding domain-like | 0 | Direct |
82671,57424
82671 - SEA domain
57424 - LDL receptor-like module | 0 | Direct |
100895,56487
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like | 0 | Direct |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
50886,50886
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
52499,47336
52499 - Isochorismatase-like hydrolases
47336 - ACP-like | 0 | Direct |
51445,49344
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | Direct |
49265,51445
49265 - Fibronectin type III
51445 - (Trans)glycosidases | 0 | Direct |
56300,56300
56300 - Metallo-dependent phosphatases
56300 - Metallo-dependent phosphatases | 0 | Direct |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
51011,50370
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | Direct |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81665,56784
81665 - Calcium ATPase, transmembrane domain M
56784 - HAD-like | 0 | Direct |
52540,49899
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
53098,47819
53098 - Ribonuclease H-like
47819 - HRDC-like | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
49899,110221
49899 - Concanavalin A-like lectins/glucanases
110221 - AbfB domain | 0 | Direct |
56487,57424
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | Direct |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | Direct |
143503,54001
143503 - PUG domain-like
54001 - Cysteine proteinases | 0 | Direct |
51445,51055
51445 - (Trans)glycosidases
51055 - Carbohydrate binding domain | 0 | Direct |
51445,49384
51445 - (Trans)glycosidases
49384 - Carbohydrate-binding domain | 0 | Direct |
52540,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like | 0 | Direct |
53955,54106
53955 - Lysozyme-like
54106 - LysM domain | 0 | Direct |
50729,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
49303,51445
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | Direct |
51445,140657
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
55608,56712
55608 - Homing endonucleases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
54236,56784
54236 - Ubiquitin-like
56784 - HAD-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
55486,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | Direct |
53092,53092
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain | 0 | Direct |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
57440,57196
57440 - Kringle-like
57196 - EGF/Laminin | 0 | Direct |
46785,51306
46785 - "Winged helix" DNA-binding domain
51306 - LexA/Signal peptidase | 0 | Direct |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
49562,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
54236,54001
54236 - Ubiquitin-like
54001 - Cysteine proteinases | 0 | Direct |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0 | Direct |
143791,143791
143791 - DUSP-like
143791 - DUSP-like | 0 | Direct |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
52540,54631
52540 - P-loop containing nucleoside triphosphate hydrolases
54631 - CBS-domain pair | 0 | Direct |
56300,55816
56300 - Metallo-dependent phosphatases
55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
49899,49599
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | Direct |
49785,51445
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | Direct |
109715,52799
109715 - DEK C-terminal domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
52743,52025
52743 - Subtilisin-like
52025 - PA domain | 0 | Direct |
55008,55008
55008 - HMA, heavy metal-associated domain
55008 - HMA, heavy metal-associated domain | 0 | Direct |
49599,54001
49599 - TRAF domain-like
54001 - Cysteine proteinases | 0 | Direct |
56568,47233
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain | 0 | Direct |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
57424,50494
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | Direct |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0.000000000000002606 | Direct |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0.000000000000004848 | Direct |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0.0000000000001924 | Direct |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.000000000004359 | Direct |
54106,54106
54106 - LysM domain
54106 - LysM domain | 0.00000000004095 | Direct |
51735,52283
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.0000000001846 | Direct |
88688,74650
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.0000000005406 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0.00000007599 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.0000007028 | Direct |
64268,50729
64268 - PX domain
50729 - PH domain-like | 0.00000154 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.000003651 | Direct |
51294,55608
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.000009579 | Direct |
51011,49452
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.000031 | Direct |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00004893 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.00005402 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0.0003174 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0004493 | Direct |
49899,50939
49899 - Concanavalin A-like lectins/glucanases
50939 - Sialidases | 0.0006227 | Direct |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.0007728 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0007728 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.001811 | Inherited |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.002481 | Inherited |
56712,51294
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0.002794 | Inherited |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.002794 | Inherited |
49785,81296
49785 - Galactose-binding domain-like
81296 - E set domains | 0.002995 | Inherited |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.009358 | Inherited |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.01132 | Inherited |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0.01132 | Inherited |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.01713 | Inherited |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.02773 | Inherited |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.03502 | Inherited |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.06229 | Inherited |
55945,48150
55945 - TATA-box binding protein-like
48150 - DNA-glycosylase | 0.08744 | Inherited |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.389 | Inherited |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.5557 | Inherited |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.6193 | Inherited |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0.6541 | Inherited |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.6958 | Inherited |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.7388 | Inherited |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | Inherited |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | Inherited |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 1 | Inherited |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 1 | Inherited |
54211,54211
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 1 | Inherited |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 1 | Inherited |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 1 | Inherited |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (Not in SPEO)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47090,55486,57440
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | DIRECT |
50729,56024,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
51445,49303,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
49384,55545,51445
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | DIRECT |
46938,52087,52799
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
49785,49785,51445
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | DIRECT |
81761,53474,49785
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | DIRECT |
54106,54106,54106
54106 - LysM domain
54106 - LysM domain
54106 - LysM domain | 0 | DIRECT |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
50249,52540,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55550,55550,50044
55550 - SH2 domain
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
52540,46785,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
49854,49854,50494
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49785,51445,49344
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | DIRECT |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55545,51445,140657
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
54001,143791,143791
54001 - Cysteine proteinases
143791 - DUSP-like
143791 - DUSP-like | 0 | DIRECT |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
47473,51695,49562
47473 - EF-hand
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
46785,158702,52540
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55486,58091,49899
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55550,55550,52799
55550 - SH2 domain
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
49785,51445,64571
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
49785,81296,48208
49785 - Galactose-binding domain-like
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | DIRECT |
53067,53067,109604
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | DIRECT |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
50044,51695,49562
50044 - SH3-domain
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55486,49899,49599
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | DIRECT |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
51294,55608,52540
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51445,140657,49785
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
51011,117100,49785
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50447,54980,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57603,57440,57440
57603 - FnI-like domain
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
51197,52540,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
52540,49899,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51278,51338,51556
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
82671,49854,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53300,100939,101420
53300 - vWA-like
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | DIRECT |
49854,49854,57424
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
51011,51445,51011
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,51294,55608
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0 | DIRECT |
53092,53092,55920
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | DIRECT |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52540,56712,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | DIRECT |
51445,51011,117100
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
54106,54106,54001
54106 - LysM domain
54106 - LysM domain
54001 - Cysteine proteinases | 0 | DIRECT |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,54980,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
55608,52540,47917
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
117100,49785,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
55781,55781,55781
55781 - GAF domain-like
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
81296,48208,63446
81296 - E set domains
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | DIRECT |
53187,49464,53187
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
56601,50886,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57424,49854,49899
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
81653,81665,56784
81653 - Calcium ATPase, transduction domain A
81665 - Calcium ATPase, transmembrane domain M
56784 - HAD-like | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
48024,52540,51294
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
56487,57424,57424
56487 - SRCR-like
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
81653,81665,81660
81653 - Calcium ATPase, transduction domain A
81665 - Calcium ATPase, transmembrane domain M
81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
49899,49854,57424
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
46785,158702,81296
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | DIRECT |
81296,51445,54556
81296 - E set domains
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49464,53187,49464
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
51445,49785,63446
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | DIRECT |
49854,49899,49854
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
56024,56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
100895,56487,57424
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | DIRECT |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
53955,54106,54106
53955 - Lysozyme-like
54106 - LysM domain
54106 - LysM domain | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49854,57424,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81624,46946,57716
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
55008,55008,55008
55008 - HMA, heavy metal-associated domain
55008 - HMA, heavy metal-associated domain
55008 - HMA, heavy metal-associated domain | 0 | DIRECT |
158702,52540,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
57630,57440,57440
57630 - GLA-domain
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
90188,53649,54060
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | DIRECT |
55545,51445,81296
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
81296 - E set domains | 0 | DIRECT |
56371,50370,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | DIRECT |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
56568,47233,52799
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
51445,51011,50370
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | DIRECT |
52540,52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
57535,57535,53300
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | DIRECT |
52540,52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | DIRECT |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
51445,49303,74650
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | DIRECT |
55267,53032,55267
55267 - tRNA-intron endonuclease N-terminal domain-like
53032 - tRNA-intron endonuclease catalytic domain-like
55267 - tRNA-intron endonuclease N-terminal domain-like | 0 | DIRECT |
58091,49899,50386
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | DIRECT |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
56784,54211,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
51445,49344,49344
51445 - (Trans)glycosidases
49344 - CBD9-like
49344 - CBD9-like | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | DIRECT |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
50494,50156,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
69065,69065,54768
69065 - RNase III domain-like
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57630,57184,50494
57630 - GLA-domain
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57424,57424,50494
57424 - LDL receptor-like module
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
49303,51445,49303
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
81324,52799,49562
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
54111,51278,51338
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
49785,49303,51445
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
53098,47819,47819
53098 - Ribonuclease H-like
47819 - HRDC-like
47819 - HRDC-like | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
55486,57440,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
55550,50044,51695
55550 - SH2 domain
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
51445,49785,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
64268,50729,56024
64268 - PX domain
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
81665,81660,56784
81665 - Calcium ATPase, transmembrane domain M
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
51445,52317,51011
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
49854,57424,56487
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
50249,47781,46929
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
54637,54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | DIRECT |
57196,57196,50494
57196 - EGF/Laminin
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57535,53300,50494
57535 - Complement control module/SCR domain
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49562,54236,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
55486,49854,82895
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
82708,53098,54928
82708 - R3H domain
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52540,50331,50331
52540 - P-loop containing nucleoside triphosphate hydrolases
50331 - MOP-like
50331 - MOP-like | 0 | DIRECT |
53032,55267,53032
53032 - tRNA-intron endonuclease catalytic domain-like
55267 - tRNA-intron endonuclease N-terminal domain-like
53032 - tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
53300,100939,68906
53300 - vWA-like
100939 - SPOC domain-like
68906 - SAP domain | 0 | DIRECT |
51445,64571,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
82671,57424,49854
82671 - SEA domain
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
52540,51294,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51445,51011,49265
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | DIRECT |
52540,52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
143503,54001,49785
143503 - PUG domain-like
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | DIRECT |
88713,88688,74650
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.0000000005406 | DIRECT |
52283,51735,52283
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.000000000833 | DIRECT |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0.0000002672 | DIRECT |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.00000139 | DIRECT |
51445,51011,49452
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.000031 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.00005402 | DIRECT |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0.0001391 | DIRECT |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.0001391 | DIRECT |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.002481 | INHERITED FROM: Dihydroorotase || In cyclic amides || Acting on carbon-nitrogen bonds, other than peptid |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.02066 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.03502 | INHERITED FROM: Dihydroorotase || In cyclic amides || Acting on carbon-nitrogen bonds, other than peptid |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.03502 | INHERITED FROM: Dihydroorotase || In cyclic amides || Acting on carbon-nitrogen bonds, other than peptid |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.03502 | INHERITED FROM: Acting on ester bonds || Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.06229 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.2959 | INHERITED FROM: Thiolester hydrolases || Oleoyl-[acyl-carrier-protein] hydrolase |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
52518,52467,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase |
81296,51445,51011
81296 - E set domains
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 1 | INHERITED FROM: Alpha-amylase || Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-gl || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehal || Pullulanase || Isoamylase |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-tyrosine-phosphatase |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47090,55486,57440
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | Direct |
50729,56024,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
51445,49303,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
49384,55545,51445
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | Direct |
46938,52087,52799
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
49785,49785,51445
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | Direct |
81761,53474,49785
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | Direct |
54106,54106,54106
54106 - LysM domain
54106 - LysM domain
54106 - LysM domain | 0 | Direct |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
50249,52540,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55550,55550,50044
55550 - SH2 domain
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
52540,46785,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
49854,49854,50494
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | Direct |
49785,51445,49344
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | Direct |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55545,51445,140657
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
54001,143791,143791
54001 - Cysteine proteinases
143791 - DUSP-like
143791 - DUSP-like | 0 | Direct |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
47473,51695,49562
47473 - EF-hand
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
46785,158702,52540
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55486,58091,49899
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55550,55550,52799
55550 - SH2 domain
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
49785,51445,64571
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | Direct |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
49785,81296,48208
49785 - Galactose-binding domain-like
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | Direct |
53067,53067,109604
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | Direct |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
50044,51695,49562
50044 - SH3-domain
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55486,49899,49599
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | Direct |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
51294,55608,52540
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51445,140657,49785
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
51011,117100,49785
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50447,54980,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
57603,57440,57440
57603 - FnI-like domain
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
51197,52540,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
52540,49899,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51278,51338,51556
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
82671,49854,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
53300,100939,101420
53300 - vWA-like
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | Direct |
49854,49854,57424
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
51011,51445,51011
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,51294,55608
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0 | Direct |
53092,53092,55920
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | Direct |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
52540,56712,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | Direct |
51445,51011,117100
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | Direct |
54106,54106,54001
54106 - LysM domain
54106 - LysM domain
54001 - Cysteine proteinases | 0 | Direct |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,54980,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
55608,52540,47917
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
117100,49785,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
55781,55781,55781
55781 - GAF domain-like
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
81296,48208,63446
81296 - E set domains
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | Direct |
53187,49464,53187
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
56601,50886,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57424,49854,49899
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
81653,81665,56784
81653 - Calcium ATPase, transduction domain A
81665 - Calcium ATPase, transmembrane domain M
56784 - HAD-like | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
48024,52540,51294
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
56487,57424,57424
56487 - SRCR-like
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
81653,81665,81660
81653 - Calcium ATPase, transduction domain A
81665 - Calcium ATPase, transmembrane domain M
81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
49899,49854,57424
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
46785,158702,81296
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | Direct |
81296,51445,54556
81296 - E set domains
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49464,53187,49464
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
51445,49785,63446
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | Direct |
49854,49899,49854
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | Direct |
56024,56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
100895,56487,57424
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | Direct |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
53955,54106,54106
53955 - Lysozyme-like
54106 - LysM domain
54106 - LysM domain | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49854,57424,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81624,46946,57716
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
55008,55008,55008
55008 - HMA, heavy metal-associated domain
55008 - HMA, heavy metal-associated domain
55008 - HMA, heavy metal-associated domain | 0 | Direct |
158702,52540,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
57630,57440,57440
57630 - GLA-domain
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
90188,53649,54060
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | Direct |
55545,51445,81296
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
81296 - E set domains | 0 | Direct |
56371,50370,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | Direct |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
56568,47233,52799
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
51445,51011,50370
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | Direct |
52540,52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
57535,57535,53300
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | Direct |
52540,52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | Direct |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
51445,49303,74650
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | Direct |
55267,53032,55267
55267 - tRNA-intron endonuclease N-terminal domain-like
53032 - tRNA-intron endonuclease catalytic domain-like
55267 - tRNA-intron endonuclease N-terminal domain-like | 0 | Direct |
58091,49899,50386
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | Direct |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
55486,49854,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
56784,54211,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
51445,49344,49344
51445 - (Trans)glycosidases
49344 - CBD9-like
49344 - CBD9-like | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | Direct |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
50494,50156,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
69065,69065,54768
69065 - RNase III domain-like
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
57630,57184,50494
57630 - GLA-domain
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | Direct |
57424,57424,50494
57424 - LDL receptor-like module
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
49303,51445,49303
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
81324,52799,49562
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
54111,51278,51338
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
49785,49303,51445
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
53098,47819,47819
53098 - Ribonuclease H-like
47819 - HRDC-like
47819 - HRDC-like | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
55486,57440,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
55550,50044,51695
55550 - SH2 domain
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | Direct |
51445,49785,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
64268,50729,56024
64268 - PX domain
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | Direct |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
81665,81660,56784
81665 - Calcium ATPase, transmembrane domain M
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
51445,52317,51011
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | Direct |
49854,57424,56487
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
50249,47781,46929
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
54637,54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | Direct |
57196,57196,50494
57196 - EGF/Laminin
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
57535,53300,50494
57535 - Complement control module/SCR domain
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | Direct |
49562,54236,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
55486,49854,82895
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
82708,53098,54928
82708 - R3H domain
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
52540,50331,50331
52540 - P-loop containing nucleoside triphosphate hydrolases
50331 - MOP-like
50331 - MOP-like | 0 | Direct |
53032,55267,53032
53032 - tRNA-intron endonuclease catalytic domain-like
55267 - tRNA-intron endonuclease N-terminal domain-like
53032 - tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
53300,100939,68906
53300 - vWA-like
100939 - SPOC domain-like
68906 - SAP domain | 0 | Direct |
51445,64571,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | Direct |
82671,57424,49854
82671 - SEA domain
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | Direct |
52540,51294,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51445,51011,49265
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | Direct |
52540,52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
143503,54001,49785
143503 - PUG domain-like
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | Direct |
88713,88688,74650
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.0000000005406 | Direct |
52283,51735,52283
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.000000000833 | Direct |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0.0000002672 | Direct |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.00000139 | Direct |
51445,51011,49452
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.000031 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.00005402 | Direct |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0.0001391 | Direct |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.0001391 | Direct |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.002481 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.02066 | Inherited |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.03502 | Inherited |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.03502 | Inherited |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.03502 | Inherited |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.06229 | Inherited |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.2959 | Inherited |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
52518,52467,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
81296,51445,51011
81296 - E set domains
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 1 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
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