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Ligases
(show info)
Enzyme Commission (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed. To navigate hierarchical structure of EC, we display all parental EC terms to the current EC term of interest ordered by their shortest distances to the current term. Also, only direct children EC terms of the current EC term are listed.
Structural Classification of Proteins (SCOP)
SCOP classifies evolutionary-related domains into Superfamily level and Family level. Accordingly, we have generated the domain-centric EC annotations for each of the three concepts at each of the two domain levels.
Structural Domain Enzyme Commission Ontology (SDEO)
As domain-centric ontology, SDEO only refers to those EC terms which are the most informative to annotate SCOP domains.
EC annotations for SCOP domains
For details, please visit Documentation: EC annotations for SCOP domains. Therein, we provide several relevant files ( Data Availability) for the download, including an annotation file (i.e., Domain2EC.txt) and the corresponding ontology (i.e., SDEO.txt).
Supra-domain Enzyme Commission Ontology (SPEO)
As an extension, SPEO includes those EC terms which are the most informative to annotate supra-domains and individual SCOP domains at the Superfamily level.
EC annotations for Supra-domains
For details, please visit Documentation: EC annotations for Supra-domains. Therein, we provide several relevant files ( Data Availability) for the download, including a annotation file (i.e., SP2EC.txt) and an ontology (i.e., SPEO.txt). For the sake of being browsable, listed below are those supra-domains (single, dual, triple, quad).
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (SDEO level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| YegP-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Ribosomal protein L25-like | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Anticodon-binding domain of PheRS | 0 | DIRECT |
| Hypothetical protein PH1602 | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| YbaK/ProRS associated domain | 0 | DIRECT |
| GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
| C-terminal domain of ProRS | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| PurS-like | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| MesJ substrate recognition domain-like | 0 | DIRECT |
| Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| PheT/TilS domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| tRNA-binding arm | 0 | DIRECT |
| Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | 0 | DIRECT |
| Argininosuccinate synthetase, C-terminal domain | 0 | DIRECT |
| Carbamoyl phosphate synthetase, large subunit connection domain | 0 | DIRECT |
| MurE/MurF N-terminal domain | 0 | DIRECT |
| Methionyl-tRNA synthetase (MetRS), Zn-domain | 0 | DIRECT |
| CoaB-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| FGAM synthase PurL, linker domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | DIRECT |
| C-terminal domain of transcriptional repressors | 0 | DIRECT |
| MurCD N-terminal domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0 | DIRECT |
| GAD domain-like | 0 | DIRECT |
| Single hybrid motif | 0.000000000001568 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.0000005415 | DIRECT |
| vWA-like | 0.04839 | INHERITED FROM: Forming nitrogen-metal bonds |
| N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0.1166 | INHERITED FROM: Forming carbon-nitrogen bonds || Phosphoribosylaminoimidazolesuccinocarboxamide syn || Acid--D-amino-acid ligases (peptide synthases) |
| Carbon-nitrogen hydrolase | 0.1417 | INHERITED FROM: Forming carbon-nitrogen bonds || NAD(+) synthase (glutamine-hydrolyzing) || Carbon--nitrogen ligases with glutamine as amido-N |
| Glycerol-3-phosphate (1)-acyltransferase | 0.2006 | INHERITED FROM: Forming carbon-sulfur bonds || Long-chain-fatty-acid--[acyl-carrier-protein] liga |
| P-loop containing nucleoside triphosphate hydrolases | 0.5689 | INHERITED FROM: Forming nitrogen-metal bonds || Cyclo-ligases || CTP synthase || Adenylosuccinate synthase || Other carbon--nitrogen ligases || Dethiobiotin synthase || Forming carbon-nitrogen bonds || Formate--tetrahydrofolate ligase |
| UBA-like | 0.5691 | INHERITED FROM: Ubiquitin--protein ligase || Acid--D-amino-acid ligases (peptide synthases) |
| EPT/RTPC-like | 1 | INHERITED FROM: RNA-3'-phosphate cyclase || Forming phosphoric ester bonds |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Formate--tetrahydrofolate ligase |
| Aldolase | 1 | INHERITED FROM: Pyruvate carboxylase |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: Phenylalanine--tRNA ligase |
| NagB/RpiA/CoA transferase-like | 1 | INHERITED FROM: 5-formyltetrahydrofolate cyclo-ligase |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | INHERITED FROM: Asparagine synthase (glutamine-hydrolyzing) || Carbon--nitrogen ligases with glutamine as amido-N |
| Formyltransferase | 1 | INHERITED FROM: Phosphoribosylamine--glycine ligase || Phosphoribosylformylglycinamidine cyclo-ligase |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin |
| post-HMGL domain-like | 1 | INHERITED FROM: Pyruvate carboxylase || Forming carbon-carbon bonds |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Succinate--CoA ligase (ADP-forming) || Succinate--CoA ligase (GDP-forming) |
| Aspartate/ornithine carbamoyltransferase | 1 | INHERITED FROM: Carbamoyl-phosphate synthase (glutamine-hydrolyzin |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| YegP-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| UBC-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Ribosomal protein L25-like | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Translation proteins | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Anticodon-binding domain of PheRS | 0 | Direct |
| Hypothetical protein PH1602 | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| ACP-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| YbaK/ProRS associated domain | 0 | Direct |
| GMP synthetase C-terminal dimerisation domain | 0 | Direct |
| C-terminal domain of ProRS | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| PurS-like | 0 | Direct |
| TGS-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| MesJ substrate recognition domain-like | 0 | Direct |
| Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| PheT/TilS domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| tRNA-binding arm | 0 | Direct |
| Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | 0 | Direct |
| Argininosuccinate synthetase, C-terminal domain | 0 | Direct |
| Carbamoyl phosphate synthetase, large subunit connection domain | 0 | Direct |
| MurE/MurF N-terminal domain | 0 | Direct |
| Methionyl-tRNA synthetase (MetRS), Zn-domain | 0 | Direct |
| CoaB-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| FGAM synthase PurL, linker domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | Direct |
| C-terminal domain of transcriptional repressors | 0 | Direct |
| MurCD N-terminal domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0 | Direct |
| GAD domain-like | 0 | Direct |
| Single hybrid motif | 0.000000000001568 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.0000005415 | Direct |
| vWA-like | 0.04839 | Inherited |
| N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0.1166 | Inherited |
| Carbon-nitrogen hydrolase | 0.1417 | Inherited |
| Glycerol-3-phosphate (1)-acyltransferase | 0.2006 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.5689 | Inherited |
| UBA-like | 0.5691 | Inherited |
| EPT/RTPC-like | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Aldolase | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| NagB/RpiA/CoA transferase-like | 1 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| post-HMGL domain-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Aspartate/ornithine carbamoyltransferase | 1 | Inherited |
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this (SDEO level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Glutamate-cysteine ligase | 0 | DIRECT |
| B3/B4 domain of PheRS, PheT | 0 | DIRECT |
| Adenylation domain of NAD+-dependent DNA ligase | 0 | DIRECT |
| Hypothetical protein PH1602 | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| MesJ substrate recognition domain-like | 0 | DIRECT |
| D-Alanine ligase N-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| PP-loop ATPase | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Biotin repressor (BirA) | 0 | DIRECT |
| Argininosuccinate synthetase, C-terminal domain | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| MurE/MurF N-terminal domain | 0 | DIRECT |
| Folylpolyglutamate synthetase, C-terminal domain | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Phenylalanyl-tRNA synthetase (PheRS) | 0 | DIRECT |
| Anticodon-binding domain of PheRS | 0 | DIRECT |
| Folylpolyglutamate synthetase | 0 | DIRECT |
| Eukaryotic glutathione synthetase, substrate-binding domain | 0 | DIRECT |
| YbaK/ProRS associated domain | 0 | DIRECT |
| tRNA-Ile-lysidine synthetase, TilS, C-terminal domain | 0 | DIRECT |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 0 | DIRECT |
| C-terminal domain of glutamyl-tRNA synthetase (GluRS) | 0 | DIRECT |
| RNA 3'-terminal phosphate cyclase, RPTC | 0 | DIRECT |
| apo-D-alanyl carrier protein | 0 | DIRECT |
| ATP-binding domain of peptide synthetases | 0 | DIRECT |
| Valyl-tRNA synthetase (ValRS) C-terminal domain | 0 | DIRECT |
| GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| YegP-like | 0 | DIRECT |
| Lysine biosynthesis enzyme LysX ATP-binding domain | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain | 0 | DIRECT |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | DIRECT |
| Glutamine synthetase catalytic domain | 0 | DIRECT |
| Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | DIRECT |
| MurCDEF C-terminal domain | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| Eukaryotic glutathione synthetase ATP-binding domain | 0 | DIRECT |
| NAD+-dependent DNA ligase, domain 3 | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| CoaB-like | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| RNA ligase | 0 | DIRECT |
| Biotin holoenzyme synthetase | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| SAICAR synthase | 0 | DIRECT |
| C-terminal domain of ProRS | 0 | DIRECT |
| Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | 0 | DIRECT |
| Carbamoyl phosphate synthetase, large subunit connection domain | 0 | DIRECT |
| MurCDEF | 0 | DIRECT |
| Methionyl-tRNA synthetase (MetRS), Zn-domain | 0 | DIRECT |
| Myf domain | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Methenyltetrahydrofolate synthetase | 0 | DIRECT |
| FGAM synthase PurL, linker domain | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Domains B1 and B5 of PheRS-beta, PheT | 0 | DIRECT |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0 | DIRECT |
| AlaX-M N-terminal domain-like | 0 | DIRECT |
| GAD domain | 0 | DIRECT |
| RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | DIRECT |
| C-terminal domain of class I lysyl-tRNA synthetase | 0 | DIRECT |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 0 | DIRECT |
| MurCD N-terminal domain | 0 | DIRECT |
| Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| AlaX-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Seryl-tRNA synthetase (SerRS) | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| FGAM synthase PurL, PurS-like domain | 0 | DIRECT |
| Prokaryotic glutathione synthetase, N-terminal domain | 0 | DIRECT |
| TGS domain | 0 | DIRECT |
| Conserved carboxylase domain | 0.0000000000006667 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0.000000000009127 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.0000007924 | DIRECT |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.006621 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
| Peptidyl carrier domain | 0.02087 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
| N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0.1316 | INHERITED FROM: Forming carbon-nitrogen bonds || Phosphoribosylaminoimidazolesuccinocarboxamide syn || Acid--D-amino-acid ligases (peptide synthases) |
| Class II glutamine amidotransferases | 0.6899 | INHERITED FROM: Forming carbon-nitrogen bonds || Asparagine synthase (glutamine-hydrolyzing) || Carbon--nitrogen ligases with glutamine as amido-N |
| Extended AAA-ATPase domain | 1 | INHERITED FROM: Forming nitrogen-metal bonds |
| HMGL-like | 1 | INHERITED FROM: Pyruvate carboxylase || Forming carbon-carbon bonds |
| Formyltransferase | 1 | INHERITED FROM: Phosphoribosylamine--glycine ligase || Phosphoribosylformylglycinamidine cyclo-ligase |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 1 | INHERITED FROM: Carbamoyl-phosphate synthase (glutamine-hydrolyzin || Carbon--nitrogen ligases with glutamine as amido-N |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 1 | INHERITED FROM: Formate--tetrahydrofolate ligase |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Formate--tetrahydrofolate ligase |
| Nucleotide and nucleoside kinases | 1 | INHERITED FROM: Pantoate--beta-alanine ligase |
| SCOP term |
FDR (all) |
Annotation (direct or inherited) |
| Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Glutamate-cysteine ligase | 0 | Direct |
| B3/B4 domain of PheRS, PheT | 0 | Direct |
| Adenylation domain of NAD+-dependent DNA ligase | 0 | Direct |
| Hypothetical protein PH1602 | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| MesJ substrate recognition domain-like | 0 | Direct |
| D-Alanine ligase N-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| PP-loop ATPase | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| DNA ligase | 0 | Direct |
| Biotin repressor (BirA) | 0 | Direct |
| Argininosuccinate synthetase, C-terminal domain | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| MurE/MurF N-terminal domain | 0 | Direct |
| Folylpolyglutamate synthetase, C-terminal domain | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Phenylalanyl-tRNA synthetase (PheRS) | 0 | Direct |
| Anticodon-binding domain of PheRS | 0 | Direct |
| Folylpolyglutamate synthetase | 0 | Direct |
| Eukaryotic glutathione synthetase, substrate-binding domain | 0 | Direct |
| YbaK/ProRS associated domain | 0 | Direct |
| tRNA-Ile-lysidine synthetase, TilS, C-terminal domain | 0 | Direct |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 0 | Direct |
| C-terminal domain of glutamyl-tRNA synthetase (GluRS) | 0 | Direct |
| RNA 3'-terminal phosphate cyclase, RPTC | 0 | Direct |
| apo-D-alanyl carrier protein | 0 | Direct |
| ATP-binding domain of peptide synthetases | 0 | Direct |
| Valyl-tRNA synthetase (ValRS) C-terminal domain | 0 | Direct |
| GMP synthetase C-terminal dimerisation domain | 0 | Direct |
| UBC-related | 0 | Direct |
| YegP-like | 0 | Direct |
| Lysine biosynthesis enzyme LysX ATP-binding domain | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain | 0 | Direct |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | Direct |
| Glutamine synthetase catalytic domain | 0 | Direct |
| Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | Direct |
| MurCDEF C-terminal domain | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| Eukaryotic glutathione synthetase ATP-binding domain | 0 | Direct |
| NAD+-dependent DNA ligase, domain 3 | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| CoaB-like | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| RNA ligase | 0 | Direct |
| Biotin holoenzyme synthetase | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| SAICAR synthase | 0 | Direct |
| C-terminal domain of ProRS | 0 | Direct |
| Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | 0 | Direct |
| Carbamoyl phosphate synthetase, large subunit connection domain | 0 | Direct |
| MurCDEF | 0 | Direct |
| Methionyl-tRNA synthetase (MetRS), Zn-domain | 0 | Direct |
| Myf domain | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Methenyltetrahydrofolate synthetase | 0 | Direct |
| FGAM synthase PurL, linker domain | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Domains B1 and B5 of PheRS-beta, PheT | 0 | Direct |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0 | Direct |
| AlaX-M N-terminal domain-like | 0 | Direct |
| GAD domain | 0 | Direct |
| RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | Direct |
| C-terminal domain of class I lysyl-tRNA synthetase | 0 | Direct |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 0 | Direct |
| MurCD N-terminal domain | 0 | Direct |
| Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| AlaX-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Seryl-tRNA synthetase (SerRS) | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| FGAM synthase PurL, PurS-like domain | 0 | Direct |
| Prokaryotic glutathione synthetase, N-terminal domain | 0 | Direct |
| TGS domain | 0 | Direct |
| Conserved carboxylase domain | 0.0000000000006667 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0.000000000009127 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.0000007924 | Direct |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.006621 | Inherited |
| Peptidyl carrier domain | 0.02087 | Inherited |
| N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0.1316 | Inherited |
| Class II glutamine amidotransferases | 0.6899 | Inherited |
| Extended AAA-ATPase domain | 1 | Inherited |
| HMGL-like | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 1 | Inherited |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 1 | Inherited |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Nucleotide and nucleoside kinases | 1 | Inherited |
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A presence/absence matrix is generated using protein domains and supradomains
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Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (SPEO level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| MurCD N-terminal domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Methionyl-tRNA synthetase (MetRS), Zn-domain | 0 | DIRECT |
| PH0987 N-terminal domain-like | 0 | DIRECT |
| MesJ substrate recognition domain-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | 0 | DIRECT |
| C-terminal domain of transcriptional repressors | 0 | DIRECT |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| PurS-like | 0 | DIRECT |
| GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
| FGAM synthase PurL, linker domain | 0 | DIRECT |
| Anticodon-binding domain of PheRS | 0 | DIRECT |
| GAD domain-like | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| Argininosuccinate synthetase, C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Hypothetical protein PH1602 | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| MurE/MurF N-terminal domain | 0 | DIRECT |
| YegP-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Ribosomal protein L25-like | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| PheT/TilS domain | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| tRNA-binding arm | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | DIRECT |
| Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | DIRECT |
| YbaK/ProRS associated domain | 0 | DIRECT |
| An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| CoaB-like | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Carbamoyl phosphate synthetase, large subunit connection domain | 0 | DIRECT |
| C-terminal domain of ProRS | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Single hybrid motif | 0.000000000001063 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.0000004246 | DIRECT |
| vWA-like | 0.04212 | INHERITED FROM: Forming nitrogen-metal bonds |
| N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0.1036 | INHERITED FROM: Forming carbon-nitrogen bonds || Phosphoribosylaminoimidazolesuccinocarboxamide syn || Acid--D-amino-acid ligases (peptide synthases) |
| Carbon-nitrogen hydrolase | 0.1255 | INHERITED FROM: Forming carbon-nitrogen bonds || NAD(+) synthase (glutamine-hydrolyzing) || Carbon--nitrogen ligases with glutamine as amido-N |
| Glycerol-3-phosphate (1)-acyltransferase | 0.1777 | INHERITED FROM: Forming carbon-sulfur bonds || Long-chain-fatty-acid--[acyl-carrier-protein] liga |
| P-loop containing nucleoside triphosphate hydrolases | 0.456 | INHERITED FROM: Forming nitrogen-metal bonds || Cyclo-ligases || CTP synthase || Adenylosuccinate synthase || Other carbon--nitrogen ligases || Dethiobiotin synthase || Forming carbon-nitrogen bonds || Formate--tetrahydrofolate ligase |
| UBA-like | 0.6322 | INHERITED FROM: Ubiquitin--protein ligase || Acid--D-amino-acid ligases (peptide synthases) |
| RING/U-box | 1 | INHERITED FROM: Ubiquitin--protein ligase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Succinate--CoA ligase (ADP-forming) || Succinate--CoA ligase (GDP-forming) |
| Acyl-CoA N-acyltransferases (Nat) | 1 | INHERITED FROM: [Citrate (pro-3S)-lyase] ligase |
| post-HMGL domain-like | 1 | INHERITED FROM: Pyruvate carboxylase || Forming carbon-carbon bonds |
| Aldolase | 1 | INHERITED FROM: Pyruvate carboxylase |
| NagB/RpiA/CoA transferase-like | 1 | INHERITED FROM: 5-formyltetrahydrofolate cyclo-ligase |
| Actin-like ATPase domain | 1 | INHERITED FROM: Biotin--[acetyl-CoA-carboxylase] ligase |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | INHERITED FROM: Asparagine synthase (glutamine-hydrolyzing) || Carbon--nitrogen ligases with glutamine as amido-N |
| Aspartate/ornithine carbamoyltransferase | 1 | INHERITED FROM: Carbamoyl-phosphate synthase (glutamine-hydrolyzin |
| EPT/RTPC-like | 1 | INHERITED FROM: RNA-3'-phosphate cyclase || Forming phosphoric ester bonds |
| PLP-dependent transferases | 1 | INHERITED FROM: 6-carboxyhexanoate--CoA ligase |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin |
| Formyltransferase | 1 | INHERITED FROM: Phosphoribosylamine--glycine ligase || Phosphoribosylformylglycinamidine cyclo-ligase |
| GST C-terminal domain-like | 1 | INHERITED FROM: Glutamate--tRNA ligase || Valine--tRNA ligase |
| CoA-dependent acyltransferases | 1 | INHERITED FROM: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Formate--tetrahydrofolate ligase |
| Cyclophilin-like | 1 | INHERITED FROM: Urea carboxylase |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: Phenylalanine--tRNA ligase || Biotin--[acetyl-CoA-carboxylase] ligase |
| Cysteine proteinases | 1 | INHERITED FROM: Glutathionylspermidine synthase |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| MurCD N-terminal domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Methionyl-tRNA synthetase (MetRS), Zn-domain | 0 | Direct |
| PH0987 N-terminal domain-like | 0 | Direct |
| MesJ substrate recognition domain-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | 0 | Direct |
| C-terminal domain of transcriptional repressors | 0 | Direct |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| PurS-like | 0 | Direct |
| GMP synthetase C-terminal dimerisation domain | 0 | Direct |
| FGAM synthase PurL, linker domain | 0 | Direct |
| Anticodon-binding domain of PheRS | 0 | Direct |
| GAD domain-like | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| ACP-like | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| Argininosuccinate synthetase, C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Hypothetical protein PH1602 | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| MurE/MurF N-terminal domain | 0 | Direct |
| YegP-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Translation proteins | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| TGS-like | 0 | Direct |
| Ribosomal protein L25-like | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| PheT/TilS domain | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| tRNA-binding arm | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| UBC-like | 0 | Direct |
| RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | Direct |
| Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | Direct |
| YbaK/ProRS associated domain | 0 | Direct |
| An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| CoaB-like | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Carbamoyl phosphate synthetase, large subunit connection domain | 0 | Direct |
| C-terminal domain of ProRS | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Single hybrid motif | 0.000000000001063 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.0000004246 | Direct |
| vWA-like | 0.04212 | Inherited |
| N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0.1036 | Inherited |
| Carbon-nitrogen hydrolase | 0.1255 | Inherited |
| Glycerol-3-phosphate (1)-acyltransferase | 0.1777 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.456 | Inherited |
| UBA-like | 0.6322 | Inherited |
| RING/U-box | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Acyl-CoA N-acyltransferases (Nat) | 1 | Inherited |
| post-HMGL domain-like | 1 | Inherited |
| Aldolase | 1 | Inherited |
| NagB/RpiA/CoA transferase-like | 1 | Inherited |
| Actin-like ATPase domain | 1 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | Inherited |
| Aspartate/ornithine carbamoyltransferase | 1 | Inherited |
| EPT/RTPC-like | 1 | Inherited |
| PLP-dependent transferases | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| GST C-terminal domain-like | 1 | Inherited |
| CoA-dependent acyltransferases | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEO level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
101353,55186
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 0 | DIRECT |
47323,47323
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
51246,55326
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0 | DIRECT |
52402,69864
52402 - Adenine nucleotide alpha hydrolases-like
69864 - Argininosuccinate synthetase, C-terminal domain | 0 | DIRECT |
51984,53623
51984 - MurCD N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
52402,54810
52402 - Adenine nucleotide alpha hydrolases-like
54810 - GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
46955,55681
46955 - Putative DNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
51735,53623
51735 - NAD(P)-binding Rossmann-fold domains
53623 - MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
47616,52374
47616 - GST C-terminal domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
101353,50447
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
50447 - Translation proteins | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
50891,160467
50891 - Cyclophilin-like
160467 - PH0987 N-terminal domain-like | 0 | DIRECT |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
109736,55326
109736 - FGAM synthase PurL, linker domain
55326 - PurM N-terminal domain-like | 0 | DIRECT |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0 | DIRECT |
50447,55186
50447 - Translation proteins
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
55681,55826
55681 - Class II aaRS and biotin synthetases
55826 - YbaK/ProRS associated domain | 0 | DIRECT |
56235,52402
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
56037,53271
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0 | DIRECT |
52402,82829
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like | 0 | DIRECT |
56317,52402
56317 - Carbon-nitrogen hydrolase
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
56042,52317
56042 - PurM C-terminal domain-like
52317 - Class I glutamine amidotransferase-like | 0 | DIRECT |
56104,52255
56104 - SAICAR synthase-like
52255 - N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0 | DIRECT |
52374,160113
52374 - Nucleotidylyl transferase
160113 - YegP-like | 0 | DIRECT |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
46589,55681
46589 - tRNA-binding arm
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
47060,52374
47060 - S15/NS1 RNA-binding domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52777,53474
52777 - CoA-dependent acyltransferases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
55931,56059
55931 - Glutamine synthetase/guanido kinase
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
55205,55205
55205 - EPT/RTPC-like
55205 - EPT/RTPC-like | 0 | DIRECT |
50249,56037
50249 - Nucleic acid-binding proteins
56037 - PheT/TilS domain | 0 | DIRECT |
50249,52113
50249 - Nucleic acid-binding proteins
52113 - BRCT domain | 0 | DIRECT |
56059,52440
56059 - Glutathione synthetase ATP-binding domain-like
52440 - PreATP-grasp domain | 0 | DIRECT |
52374,50715
52374 - Nucleotidylyl transferase
50715 - Ribosomal protein L25-like | 0 | DIRECT |
53244,52440
53244 - MurD-like peptide ligases, peptide-binding domain
52440 - PreATP-grasp domain | 0 | DIRECT |
47781,52113
47781 - RuvA domain 2-like
52113 - BRCT domain | 0 | DIRECT |
56042,55326
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 0 | DIRECT |
46785,55681
46785 - "Winged helix" DNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
82829,56037
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 0 | DIRECT |
52374,48163
52374 - Nucleotidylyl transferase
48163 - An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
55681,55261
55681 - Class II aaRS and biotin synthetases
55261 - GAD domain-like | 0 | DIRECT |
47323,47060
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47060 - S15/NS1 RNA-binding domain | 0 | DIRECT |
52374,50249
52374 - Nucleotidylyl transferase
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54001,56059
54001 - Cysteine proteinases
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
56037,46955
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain | 0 | DIRECT |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
69593,56801
69593 - Glycerol-3-phosphate (1)-acyltransferase
56801 - Acetyl-CoA synthetase-like | 0 | DIRECT |
56042,53328
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | DIRECT |
55190,52374
55190 - Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0 | DIRECT |
52402,56037
52402 - Adenine nucleotide alpha hydrolases-like
56037 - PheT/TilS domain | 0 | DIRECT |
51735,52210
51735 - NAD(P)-binding Rossmann-fold domains
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
55681,54991
55681 - Class II aaRS and biotin synthetases
54991 - Anticodon-binding domain of PheRS | 0 | DIRECT |
52507,102645
52507 - Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
102645 - CoaB-like | 0 | DIRECT |
55729,52374
55729 - Acyl-CoA N-acyltransferases (Nat)
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52374,55174
52374 - Nucleotidylyl transferase
55174 - Alpha-L RNA-binding motif | 0 | DIRECT |
55205,52913
55205 - EPT/RTPC-like
52913 - RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | DIRECT |
47060,47060
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain | 0 | DIRECT |
54810,54810
54810 - GMP synthetase C-terminal dimerisation domain
54810 - GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
82697,109736
82697 - PurS-like
109736 - FGAM synthase PurL, linker domain | 0 | DIRECT |
52540,52317
52540 - P-loop containing nucleoside triphosphate hydrolases
52317 - Class I glutamine amidotransferase-like | 0 | DIRECT |
55186,55681
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
109604,47323
109604 - HD-domain/PDEase-like
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0 | DIRECT |
47323,50249
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
160467,50891
160467 - PH0987 N-terminal domain-like
50891 - Cyclophilin-like | 0 | DIRECT |
63418,53623
63418 - MurE/MurF N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
47323,46589
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
46589 - tRNA-binding arm | 0 | DIRECT |
56059,53623
56059 - Glutathione synthetase ATP-binding domain-like
53623 - MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
57770,52374
57770 - Methionyl-tRNA synthetase (MetRS), Zn-domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 0 | DIRECT |
46955,56037
46955 - Putative DNA-binding domain
56037 - PheT/TilS domain | 0 | DIRECT |
52317,52402
52317 - Class I glutamine amidotransferase-like
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
52954,64586
52954 - Class II aaRS ABD-related
64586 - C-terminal domain of ProRS | 0 | DIRECT |
55681,101353
55681 - Class II aaRS and biotin synthetases
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | DIRECT |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00000000139 | DIRECT |
52777,56801
52777 - CoA-dependent acyltransferases
56801 - Acetyl-CoA synthetase-like | 0.002256 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0.004645 | INHERITED FROM: Phenylalanine--tRNA ligase || Forming carbon-oxygen bonds || Ligases forming aminoacyl-tRNA and related compoun |
56801,47336
56801 - Acetyl-CoA synthetase-like
47336 - ACP-like | 0.007925 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
47336,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.01651 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.8561 | INHERITED FROM: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 1 | INHERITED FROM: Carbamoyl-phosphate synthase (glutamine-hydrolyzin |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Formate--tetrahydrofolate ligase |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | INHERITED FROM: Biotin--[acetyl-CoA-carboxylase] ligase |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 1 | INHERITED FROM: Pyruvate carboxylase || Forming carbon-carbon bonds |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
101353,55186
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
55186 - ThrRS/AlaRS common domain | 0 | Direct |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 0 | Direct |
47323,47323
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
51246,55326
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0 | Direct |
52402,69864
52402 - Adenine nucleotide alpha hydrolases-like
69864 - Argininosuccinate synthetase, C-terminal domain | 0 | Direct |
51984,53623
51984 - MurCD N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain | 0 | Direct |
52402,54810
52402 - Adenine nucleotide alpha hydrolases-like
54810 - GMP synthetase C-terminal dimerisation domain | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
46955,55681
46955 - Putative DNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
51735,53623
51735 - NAD(P)-binding Rossmann-fold domains
53623 - MurD-like peptide ligases, catalytic domain | 0 | Direct |
47616,52374
47616 - GST C-terminal domain-like
52374 - Nucleotidylyl transferase | 0 | Direct |
101353,50447
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
50447 - Translation proteins | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
50891,160467
50891 - Cyclophilin-like
160467 - PH0987 N-terminal domain-like | 0 | Direct |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
109736,55326
109736 - FGAM synthase PurL, linker domain
55326 - PurM N-terminal domain-like | 0 | Direct |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0 | Direct |
50447,55186
50447 - Translation proteins
55186 - ThrRS/AlaRS common domain | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
55681,55826
55681 - Class II aaRS and biotin synthetases
55826 - YbaK/ProRS associated domain | 0 | Direct |
56235,52402
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
56037,53271
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0 | Direct |
52402,82829
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like | 0 | Direct |
56317,52402
56317 - Carbon-nitrogen hydrolase
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
56042,52317
56042 - PurM C-terminal domain-like
52317 - Class I glutamine amidotransferase-like | 0 | Direct |
56104,52255
56104 - SAICAR synthase-like
52255 - N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 0 | Direct |
52374,160113
52374 - Nucleotidylyl transferase
160113 - YegP-like | 0 | Direct |
47781,47781
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
47060,55681
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
46589,55681
46589 - tRNA-binding arm
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
47060,52374
47060 - S15/NS1 RNA-binding domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52777,53474
52777 - CoA-dependent acyltransferases
53474 - alpha/beta-Hydrolases | 0 | Direct |
55931,56059
55931 - Glutamine synthetase/guanido kinase
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
55205,55205
55205 - EPT/RTPC-like
55205 - EPT/RTPC-like | 0 | Direct |
50249,56037
50249 - Nucleic acid-binding proteins
56037 - PheT/TilS domain | 0 | Direct |
50249,52113
50249 - Nucleic acid-binding proteins
52113 - BRCT domain | 0 | Direct |
56059,52440
56059 - Glutathione synthetase ATP-binding domain-like
52440 - PreATP-grasp domain | 0 | Direct |
52374,50715
52374 - Nucleotidylyl transferase
50715 - Ribosomal protein L25-like | 0 | Direct |
53244,52440
53244 - MurD-like peptide ligases, peptide-binding domain
52440 - PreATP-grasp domain | 0 | Direct |
47781,52113
47781 - RuvA domain 2-like
52113 - BRCT domain | 0 | Direct |
56042,55326
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 0 | Direct |
46785,55681
46785 - "Winged helix" DNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
82829,56037
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 0 | Direct |
52374,48163
52374 - Nucleotidylyl transferase
48163 - An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 0 | Direct |
55681,55261
55681 - Class II aaRS and biotin synthetases
55261 - GAD domain-like | 0 | Direct |
47323,47060
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47060 - S15/NS1 RNA-binding domain | 0 | Direct |
52374,50249
52374 - Nucleotidylyl transferase
50249 - Nucleic acid-binding proteins | 0 | Direct |
54001,56059
54001 - Cysteine proteinases
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | Direct |
56037,46955
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain | 0 | Direct |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
69593,56801
69593 - Glycerol-3-phosphate (1)-acyltransferase
56801 - Acetyl-CoA synthetase-like | 0 | Direct |
56042,53328
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | Direct |
55190,52374
55190 - Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
52374 - Nucleotidylyl transferase | 0 | Direct |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0 | Direct |
52402,56037
52402 - Adenine nucleotide alpha hydrolases-like
56037 - PheT/TilS domain | 0 | Direct |
51735,52210
51735 - NAD(P)-binding Rossmann-fold domains
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
55681,54991
55681 - Class II aaRS and biotin synthetases
54991 - Anticodon-binding domain of PheRS | 0 | Direct |
52507,102645
52507 - Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
102645 - CoaB-like | 0 | Direct |
55729,52374
55729 - Acyl-CoA N-acyltransferases (Nat)
52374 - Nucleotidylyl transferase | 0 | Direct |
52374,55174
52374 - Nucleotidylyl transferase
55174 - Alpha-L RNA-binding motif | 0 | Direct |
55205,52913
55205 - EPT/RTPC-like
52913 - RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | Direct |
47060,47060
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain | 0 | Direct |
54810,54810
54810 - GMP synthetase C-terminal dimerisation domain
54810 - GMP synthetase C-terminal dimerisation domain | 0 | Direct |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
82697,109736
82697 - PurS-like
109736 - FGAM synthase PurL, linker domain | 0 | Direct |
52540,52317
52540 - P-loop containing nucleoside triphosphate hydrolases
52317 - Class I glutamine amidotransferase-like | 0 | Direct |
55186,55681
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
109604,47323
109604 - HD-domain/PDEase-like
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0 | Direct |
47323,50249
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
50249 - Nucleic acid-binding proteins | 0 | Direct |
160467,50891
160467 - PH0987 N-terminal domain-like
50891 - Cyclophilin-like | 0 | Direct |
63418,53623
63418 - MurE/MurF N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain | 0 | Direct |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | Direct |
47323,46589
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
46589 - tRNA-binding arm | 0 | Direct |
56059,53623
56059 - Glutathione synthetase ATP-binding domain-like
53623 - MurD-like peptide ligases, catalytic domain | 0 | Direct |
57770,52374
57770 - Methionyl-tRNA synthetase (MetRS), Zn-domain
52374 - Nucleotidylyl transferase | 0 | Direct |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 0 | Direct |
46955,56037
46955 - Putative DNA-binding domain
56037 - PheT/TilS domain | 0 | Direct |
52317,52402
52317 - Class I glutamine amidotransferase-like
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
52954,64586
52954 - Class II aaRS ABD-related
64586 - C-terminal domain of ProRS | 0 | Direct |
55681,101353
55681 - Class II aaRS and biotin synthetases
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0 | Direct |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00000000139 | Direct |
52777,56801
52777 - CoA-dependent acyltransferases
56801 - Acetyl-CoA synthetase-like | 0.002256 | Inherited |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0.004645 | Inherited |
56801,47336
56801 - Acetyl-CoA synthetase-like
47336 - ACP-like | 0.007925 | Inherited |
47336,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.01651 | Inherited |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.8561 | Inherited |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 1 | Inherited |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | Inherited |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEO level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53244,52440,56059
53244 - MurD-like peptide ligases, peptide-binding domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
51984,53623,53244
51984 - MurCD N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
47616,52374,50715
47616 - GST C-terminal domain-like
52374 - Nucleotidylyl transferase
50715 - Ribosomal protein L25-like | 0 | DIRECT |
56091,50249,52113
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins
52113 - BRCT domain | 0 | DIRECT |
50249,55681,55261
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases
55261 - GAD domain-like | 0 | DIRECT |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
52374,47323,50249
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
55186,55681,52954
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
46955,55681,54991
46955 - Putative DNA-binding domain
55681 - Class II aaRS and biotin synthetases
54991 - Anticodon-binding domain of PheRS | 0 | DIRECT |
47781,47781,52113
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like
52113 - BRCT domain | 0 | DIRECT |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
55326,56042,53328
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | DIRECT |
52402,54810,54810
52402 - Adenine nucleotide alpha hydrolases-like
54810 - GMP synthetase C-terminal dimerisation domain
54810 - GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
52777,52777,53474
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
50249,47781,52113
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
52113 - BRCT domain | 0 | DIRECT |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0 | DIRECT |
51246,55326,56042
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
47060,55681,52954
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
55681,52954,64586
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related
64586 - C-terminal domain of ProRS | 0 | DIRECT |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
52374,47323,47060
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47060 - S15/NS1 RNA-binding domain | 0 | DIRECT |
55326,56042,52317
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
52317 - Class I glutamine amidotransferase-like | 0 | DIRECT |
50249,56037,46955
50249 - Nucleic acid-binding proteins
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain | 0 | DIRECT |
50677,52374,47323
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
57770,52374,47323
57770 - Methionyl-tRNA synthetase (MetRS), Zn-domain
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
56059,53623,53244
56059 - Glutathione synthetase ATP-binding domain-like
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
53623,53244,52440
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain
52440 - PreATP-grasp domain | 0 | DIRECT |
52402,82829,56037
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 0 | DIRECT |
50249,52113,52113
50249 - Nucleic acid-binding proteins
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
50891,160467,50891
50891 - Cyclophilin-like
160467 - PH0987 N-terminal domain-like
50891 - Cyclophilin-like | 0 | DIRECT |
81271,55186,55681
81271 - TGS-like
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
55205,55205,52913
55205 - EPT/RTPC-like
55205 - EPT/RTPC-like
52913 - RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | DIRECT |
55326,56042,55326
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 0 | DIRECT |
47060,47060,55681
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
101353,50447,55186
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
50447 - Translation proteins
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
56042,55326,56042
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
54001,56059,52440
54001 - Cysteine proteinases
56059 - Glutathione synthetase ATP-binding domain-like
52440 - PreATP-grasp domain | 0 | DIRECT |
55681,101353,55186
55681 - Class II aaRS and biotin synthetases
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
56059,51246,55326
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0 | DIRECT |
56037,46955,55681
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
109736,55326,56042
109736 - FGAM synthase PurL, linker domain
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
56091,50249,47781
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | DIRECT |
55681,101353,50447
55681 - Class II aaRS and biotin synthetases
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
50447 - Translation proteins | 0 | DIRECT |
47060,47060,47060
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain | 0 | DIRECT |
52374,47323,46589
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
46589 - tRNA-binding arm | 0 | DIRECT |
46785,55681,50037
46785 - "Winged helix" DNA-binding domain
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0 | DIRECT |
55190,52374,47323
55190 - Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
50249,47781,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | DIRECT |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0 | DIRECT |
63418,53623,53244
63418 - MurE/MurF N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
51735,53623,53244
51735 - NAD(P)-binding Rossmann-fold domains
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
82697,109736,55326
82697 - PurS-like
109736 - FGAM synthase PurL, linker domain
55326 - PurM N-terminal domain-like | 0 | DIRECT |
46955,56037,46955
46955 - Putative DNA-binding domain
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain | 0 | DIRECT |
52317,52402,54810
52317 - Class I glutamine amidotransferase-like
52402 - Adenine nucleotide alpha hydrolases-like
54810 - GMP synthetase C-terminal dimerisation domain | 0 | DIRECT |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0 | DIRECT |
82829,56037,53271
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | DIRECT |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
52777,52777,56801
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases
56801 - Acetyl-CoA synthetase-like | 0.0004185 | DIRECT |
52777,56801,47336
52777 - CoA-dependent acyltransferases
56801 - Acetyl-CoA synthetase-like
47336 - ACP-like | 0.000919 | DIRECT |
56801,47336,52777
56801 - Acetyl-CoA synthetase-like
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.003129 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
47336,52777,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.01651 | INHERITED FROM: Forming carbon-nitrogen bonds || N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin || Acid--D-amino-acid ligases (peptide synthases) |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53244,52440,56059
53244 - MurD-like peptide ligases, peptide-binding domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
51984,53623,53244
51984 - MurCD N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
47616,52374,50715
47616 - GST C-terminal domain-like
52374 - Nucleotidylyl transferase
50715 - Ribosomal protein L25-like | 0 | Direct |
56091,50249,52113
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins
52113 - BRCT domain | 0 | Direct |
50249,55681,55261
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases
55261 - GAD domain-like | 0 | Direct |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
52374,47323,50249
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
50249 - Nucleic acid-binding proteins | 0 | Direct |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
55186,55681,52954
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
46955,55681,54991
46955 - Putative DNA-binding domain
55681 - Class II aaRS and biotin synthetases
54991 - Anticodon-binding domain of PheRS | 0 | Direct |
47781,47781,52113
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like
52113 - BRCT domain | 0 | Direct |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
55326,56042,53328
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | Direct |
52402,54810,54810
52402 - Adenine nucleotide alpha hydrolases-like
54810 - GMP synthetase C-terminal dimerisation domain
54810 - GMP synthetase C-terminal dimerisation domain | 0 | Direct |
52777,52777,53474
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases
53474 - alpha/beta-Hydrolases | 0 | Direct |
50249,47781,52113
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
52113 - BRCT domain | 0 | Direct |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 0 | Direct |
51246,55326,56042
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
47060,55681,52954
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
55681,52954,64586
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related
64586 - C-terminal domain of ProRS | 0 | Direct |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | Direct |
52374,47323,47060
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47060 - S15/NS1 RNA-binding domain | 0 | Direct |
55326,56042,52317
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
52317 - Class I glutamine amidotransferase-like | 0 | Direct |
50249,56037,46955
50249 - Nucleic acid-binding proteins
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain | 0 | Direct |
50677,52374,47323
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
57770,52374,47323
57770 - Methionyl-tRNA synthetase (MetRS), Zn-domain
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
56059,53623,53244
56059 - Glutathione synthetase ATP-binding domain-like
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
53623,53244,52440
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain
52440 - PreATP-grasp domain | 0 | Direct |
52402,82829,56037
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 0 | Direct |
50249,52113,52113
50249 - Nucleic acid-binding proteins
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
50891,160467,50891
50891 - Cyclophilin-like
160467 - PH0987 N-terminal domain-like
50891 - Cyclophilin-like | 0 | Direct |
81271,55186,55681
81271 - TGS-like
55186 - ThrRS/AlaRS common domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
55205,55205,52913
55205 - EPT/RTPC-like
55205 - EPT/RTPC-like
52913 - RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 0 | Direct |
55326,56042,55326
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 0 | Direct |
47060,47060,55681
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
101353,50447,55186
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
50447 - Translation proteins
55186 - ThrRS/AlaRS common domain | 0 | Direct |
56042,55326,56042
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
54001,56059,52440
54001 - Cysteine proteinases
56059 - Glutathione synthetase ATP-binding domain-like
52440 - PreATP-grasp domain | 0 | Direct |
55681,101353,55186
55681 - Class II aaRS and biotin synthetases
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
55186 - ThrRS/AlaRS common domain | 0 | Direct |
56059,51246,55326
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0 | Direct |
56037,46955,55681
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
109736,55326,56042
109736 - FGAM synthase PurL, linker domain
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
56091,50249,47781
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | Direct |
55681,101353,50447
55681 - Class II aaRS and biotin synthetases
101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
50447 - Translation proteins | 0 | Direct |
47060,47060,47060
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain
47060 - S15/NS1 RNA-binding domain | 0 | Direct |
52374,47323,46589
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
46589 - tRNA-binding arm | 0 | Direct |
46785,55681,50037
46785 - "Winged helix" DNA-binding domain
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0 | Direct |
55190,52374,47323
55190 - Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
50249,47781,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
47781 - RuvA domain 2-like | 0 | Direct |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0 | Direct |
63418,53623,53244
63418 - MurE/MurF N-terminal domain
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
51735,53623,53244
51735 - NAD(P)-binding Rossmann-fold domains
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
82697,109736,55326
82697 - PurS-like
109736 - FGAM synthase PurL, linker domain
55326 - PurM N-terminal domain-like | 0 | Direct |
46955,56037,46955
46955 - Putative DNA-binding domain
56037 - PheT/TilS domain
46955 - Putative DNA-binding domain | 0 | Direct |
52317,52402,54810
52317 - Class I glutamine amidotransferase-like
52402 - Adenine nucleotide alpha hydrolases-like
54810 - GMP synthetase C-terminal dimerisation domain | 0 | Direct |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 0 | Direct |
82829,56037,53271
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | Direct |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
52777,52777,56801
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases
56801 - Acetyl-CoA synthetase-like | 0.0004185 | Direct |
52777,56801,47336
52777 - CoA-dependent acyltransferases
56801 - Acetyl-CoA synthetase-like
47336 - ACP-like | 0.000919 | Direct |
56801,47336,52777
56801 - Acetyl-CoA synthetase-like
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.003129 | Inherited |
47336,52777,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.01651 | Inherited |
Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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