| 171 | 111 | 9 | 0 | SCOP 50494 | Trypsin-like serine proteases |
| 123 | 47 | 18 | 0 | SCOP 57667 | beta-beta-alpha zinc fingers |
| 64 | 19 | 14 | 0 | SCOP 48726 | Immunoglobulin |
| 36 | 32 | 11 | 5 | SCOP 52540 | P-loop containing nucleoside triphosphate hydrolases |
| 28 | 27 | 3 | 0 | SCOP 57903 | FYVE/PHD zinc finger |
| 25 | 7 | 6 | 0 | SCOP 49313 | Cadherin-like |
| 23 | 23 | 8 | 0 | SCOP 57716 | Glucocorticoid receptor-like (DNA-binding domain) |
| 22 | 22 | 2 | 1 | SCOP 56496 | Fibrinogen C-terminal domain-like |
| 19 | 19 | 5 | 2 | SCOP 53474 | alpha/beta-Hydrolases |
| 19 | 2 | 2 | 0 | SCOP 90148 | DPY module |
| 18 | 18 | 4 | 1 | SCOP 56112 | Protein kinase-like (PK-like) |
| 18 | 18 | 2 | 1 | SCOP 48264 | Cytochrome P450 |
| 17 | 16 | 5 | 2 | SCOP 55486 | Metalloproteases ("zincins"), catalytic domain |
| 15 | 15 | 6 | 0 | SCOP 52058 | L domain-like |
| 14 | 9 | 7 | 0 | SCOP 90123 | ABC transporter transmembrane region |
| 12 | 8 | 5 | 0 | SCOP 81324 | Voltage-gated potassium channels |
| 11 | 11 | 4 | 1 | SCOP 53187 | Zn-dependent exopeptidases |
| 10 | 10 | 4 | 1 | SCOP 53448 | Nucleotide-diphospho-sugar transferases |
| 10 | 10 | 6 | 1 | SCOP 51445 | (Trans)glycosidases |
| 10 | 7 | 6 | 0 | SCOP 49899 | Concanavalin A-like lectins/glucanases |
| 10 | 6 | 6 | 0 | SCOP 49265 | Fibronectin type III |
| 9 | 7 | 5 | 0 | SCOP 51735 | NAD(P)-binding Rossmann-fold domains |
| 9 | 9 | 5 | 2 | SCOP 81296 | E set domains |
| 9 | 7 | 5 | 0 | SCOP 48403 | Ankyrin repeat |
| 9 | 8 | 4 | 1 | SCOP 48113 | Heme-dependent peroxidases |
| 9 | 5 | 2 | 1 | SCOP 47203 | Acyl-CoA dehydrogenase C-terminal domain-like |
| 9 | 9 | 2 | 0 | SCOP 48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| 9 | 5 | 4 | 0 | SCOP 57625 | Invertebrate chitin-binding proteins |
| 8 | 8 | 2 | 0 | SCOP 103473 | MFS general substrate transporter |
| 8 | 2 | 2 | 1 | SCOP 55753 | Actin depolymerizing proteins |
| 7 | 7 | 2 | 1 | SCOP 51905 | FAD/NAD(P)-binding domain |
| 7 | 6 | 3 | 0 | SCOP 63737 | Leukotriene A4 hydrolase N-terminal domain |
| 7 | 7 | 6 | 0 | SCOP 144232 | HIT/MYND zinc finger-like |
| 7 | 7 | 2 | 0 | SCOP 54373 | FAD-linked reductases, C-terminal domain |
| 6 | 5 | 3 | 1 | SCOP 46689 | Homeodomain-like |
| 6 | 6 | 1 | 0 | SCOP 81321 | Family A G protein-coupled receptor-like |
| 6 | 6 | 1 | 1 | SCOP 161070 | SNF-like |
| 6 | 6 | 4 | 0 | SCOP 82199 | SET domain |
| 6 | 6 | 2 | 0 | SCOP 50370 | Ricin B-like lectins |
| 5 | 5 | 3 | 1 | SCOP 54928 | RNA-binding domain, RBD |
| 5 | 5 | 2 | 2 | SCOP 56645 | Acyl-CoA dehydrogenase NM domain-like |
| 5 | 1 | 1 | 0 | SCOP 46966 | Spectrin repeat |
| 4 | 4 | 4 | 1 | SCOP 46785 | "Winged helix" DNA-binding domain |
| 4 | 4 | 4 | 0 | SCOP 48452 | TPR-like |
| 4 | 4 | 1 | 1 | SCOP 56801 | Acetyl-CoA synthetase-like |
| 4 | 4 | 2 | 0 | SCOP 57850 | RING/U-box |
| 4 | 3 | 3 | 1 | SCOP 55797 | PR-1-like |
| 4 | 2 | 2 | 1 | SCOP 55945 | TATA-box binding protein-like |
| 4 | 4 | 1 | 0 | SCOP 46938 | CRAL/TRIO N-terminal domain |
| 4 | 4 | 3 | 0 | SCOP 63748 | Tudor/PWWP/MBT |
| 4 | 4 | 1 | 0 | SCOP 57845 | B-box zinc-binding domain |
| 4 | 4 | 1 | 1 | SCOP 52087 | CRAL/TRIO domain |
| 3 | 3 | 1 | 1 | SCOP 53335 | S-adenosyl-L-methionine-dependent methyltransferases |
| 3 | 3 | 2 | 1 | SCOP 56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| 3 | 2 | 2 | 1 | SCOP 52799 | (Phosphotyrosine protein) phosphatases II |
| 3 | 3 | 2 | 0 | SCOP 55729 | Acyl-CoA N-acyltransferases (Nat) |
| 3 | 3 | 2 | 1 | SCOP 48239 | Terpenoid cyclases/Protein prenyltransferases |
| 3 | 3 | 2 | 0 | SCOP 50044 | SH3-domain |
| 3 | 3 | 1 | 1 | SCOP 49777 | PEBP-like |
| 3 | 2 | 2 | 0 | SCOP 49503 | Cupredoxins |
| 3 | 3 | 2 | 0 | SCOP 52200 | Toll/Interleukin receptor TIR domain |
| 3 | 3 | 3 | 1 | SCOP 56176 | FAD-binding/transporter-associated domain-like |
| 3 | 3 | 1 | 0 | SCOP 52129 | Caspase-like |
| 3 | 2 | 2 | 0 | SCOP 57184 | Growth factor receptor domain |
| 3 | 3 | 1 | 0 | SCOP 63712 | Nicotinic receptor ligand binding domain-like |
| 3 | 3 | 3 | 0 | SCOP 57196 | EGF/Laminin |
| 3 | 1 | 1 | 0 | SCOP 57424 | LDL receptor-like module |
| 2 | 2 | 2 | 0 | SCOP 50249 | Nucleic acid-binding proteins |
| 2 | 2 | 2 | 0 | SCOP 52833 | Thioredoxin-like |
| 2 | 2 | 1 | 0 | SCOP 69593 | Glycerol-3-phosphate (1)-acyltransferase |
| 2 | 2 | 1 | 0 | SCOP 47336 | ACP-like |
| 2 | 2 | 1 | 1 | SCOP 53383 | PLP-dependent transferases |
| 2 | 2 | 1 | 0 | SCOP 50129 | GroES-like |
| 2 | 2 | 1 | 0 | SCOP 53850 | Periplasmic binding protein-like II |
| 2 | 2 | 2 | 2 | SCOP 54211 | Ribosomal protein S5 domain 2-like |
| 2 | 2 | 2 | 1 | SCOP 47113 | Histone-fold |
| 2 | 2 | 2 | 1 | SCOP 47473 | EF-hand |
| 2 | 2 | 1 | 1 | SCOP 51430 | NAD(P)-linked oxidoreductase |
| 2 | 2 | 2 | 0 | SCOP 50978 | WD40 repeat-like |
| 2 | 2 | 2 | 1 | SCOP 54001 | Cysteine proteinases |
| 2 | 2 | 1 | 0 | SCOP 49785 | Galactose-binding domain-like |
| 2 | 2 | 1 | 0 | SCOP 54897 | Protease propeptides/inhibitors |
| 2 | 2 | 1 | 1 | SCOP 74650 | Galactose mutarotase-like |
| 2 | 2 | 1 | 1 | SCOP 88713 | Glycoside hydrolase/deacetylase |
| 2 | 2 | 1 | 0 | SCOP 52151 | FabD/lysophospholipase-like |
| 2 | 2 | 2 | 0 | SCOP 64268 | PX domain |
| 2 | 2 | 1 | 0 | SCOP 54695 | POZ domain |
| 2 | 2 | 1 | 0 | SCOP 52091 | SpoIIaa-like |
| 2 | 1 | 1 | 0 | SCOP 54909 | Dimeric alpha+beta barrel |
| 2 | 2 | 1 | 0 | SCOP 53901 | Thiolase-like |
| 2 | 1 | 1 | 1 | SCOP 56574 | Serpins |
| 2 | 2 | 2 | 1 | SCOP 47616 | GST C-terminal domain-like |
| 2 | 2 | 2 | 0 | SCOP 101898 | NHL repeat |
| 2 | 2 | 2 | 1 | SCOP 54665 | CO dehydrogenase molybdoprotein N-domain-like |
| 2 | 2 | 2 | 1 | SCOP 55447 | CO dehydrogenase flavoprotein C-terminal domain-like |
| 2 | 2 | 2 | 0 | SCOP 47459 | HLH, helix-loop-helix DNA-binding domain |
| 2 | 2 | 1 | 0 | SCOP 55550 | SH2 domain |
| 2 | 1 | 1 | 0 | SCOP 49742 | PHM/PNGase F |
| 2 | 2 | 1 | 0 | SCOP 49410 | Alpha-macroglobulin receptor domain |
| 2 | 2 | 2 | 0 | SCOP 49562 | C2 domain (Calcium/lipid-binding domain, CaLB) |
| 2 | 2 | 1 | 0 | SCOP 100895 | Kazal-type serine protease inhibitors |
| 2 | 1 | 1 | 0 | SCOP 57889 | Cysteine-rich domain |
| 2 | 1 | 1 | 1 | SCOP 57924 | Inhibitor of apoptosis (IAP) repeat |
| 2 | 1 | 1 | 0 | SCOP 56968 | Lipovitellin-phosvitin complex; beta-sheet shell regions |
| 2 | 2 | 1 | 1 | SCOP 88688 | Families 57/38 glycoside transferase middle domain |
| 2 | 2 | 1 | 0 | SCOP 57959 | Leucine zipper domain |
| 1 | 1 | 1 | 1 | SCOP 51556 | Metallo-dependent hydrolases |
| 1 | 1 | 1 | 0 | SCOP 81338 | Aquaporin-like |
| 1 | 1 | 1 | 0 | SCOP 52374 | Nucleotidylyl transferase |
| 1 | 1 | 1 | 0 | SCOP 56300 | Metallo-dependent phosphatases |
| 1 | 1 | 1 | 0 | SCOP 53098 | Ribonuclease H-like |
| 1 | 1 | 1 | 0 | SCOP 53720 | ALDH-like |
| 1 | 1 | 1 | 1 | SCOP 54292 | 2Fe-2S ferredoxin-like |
| 1 | 1 | 1 | 0 | SCOP 53756 | UDP-Glycosyltransferase/glycogen phosphorylase |
| 1 | 1 | 1 | 1 | SCOP 48371 | ARM repeat |
| 1 | 1 | 1 | 0 | SCOP 103506 | Mitochondrial carrier |
| 1 | 1 | 1 | 0 | SCOP 54495 | UBC-like |
| 1 | 1 | 1 | 0 | SCOP 48256 | Citrate synthase |
| 1 | 1 | 1 | 1 | SCOP 50891 | Cyclophilin-like |
| 1 | 1 | 1 | 1 | SCOP 56815 | Sec1/munc18-like (SM) proteins |
| 1 | 1 | 1 | 0 | SCOP 54534 | FKBP-like |
| 1 | 1 | 1 | 1 | SCOP 53649 | Alkaline phosphatase-like |
| 1 | 1 | 1 | 0 | SCOP 69572 | Activating enzymes of the ubiquitin-like proteins |
| 1 | 1 | 1 | 0 | SCOP 51126 | Pectin lyase-like |
| 1 | 1 | 1 | 0 | SCOP 51197 | Clavaminate synthase-like |
| 1 | 1 | 1 | 0 | SCOP 54919 | Nucleoside diphosphate kinase, NDK |
| 1 | 1 | 1 | 0 | SCOP 82282 | Homocysteine S-methyltransferase |
| 1 | 1 | 1 | 0 | SCOP 103486 | V-type ATP synthase subunit C |
| 1 | 1 | 1 | 0 | SCOP 55856 | Cytochrome b5-like heme/steroid binding domain |
| 1 | 1 | 1 | 0 | SCOP 50447 | Translation proteins |
| 1 | 1 | 1 | 0 | SCOP 47576 | Calponin-homology domain, CH-domain |
| 1 | 1 | 1 | 0 | SCOP 52283 | Formate/glycerate dehydrogenase catalytic domain-like |
| 1 | 1 | 1 | 1 | SCOP 55931 | Glutamine synthetase/guanido kinase |
| 1 | 1 | 1 | 0 | SCOP 161084 | MAPEG domain-like |
| 1 | 1 | 1 | 0 | SCOP 111038 | YjbQ-like |
| 1 | 1 | 1 | 0 | SCOP 51998 | PFL-like glycyl radical enzymes |
| 1 | 1 | 1 | 1 | SCOP 55874 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| 1 | 1 | 1 | 0 | SCOP 89550 | PHP domain-like |
| 1 | 1 | 1 | 0 | SCOP 82153 | FAS1 domain |
| 1 | 1 | 1 | 0 | SCOP 55785 | PYP-like sensor domain (PAS domain) |
| 1 | 1 | 1 | 0 | SCOP 82171 | DPP6 N-terminal domain-like |
| 1 | 1 | 1 | 0 | SCOP 50465 | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |
| 1 | 1 | 1 | 1 | SCOP 56003 | Molybdenum cofactor-binding domain |
| 1 | 1 | 1 | 0 | SCOP 82866 | Multidrug efflux transporter AcrB transmembrane domain |
| 1 | 1 | 1 | 0 | SCOP 48592 | GroEL equatorial domain-like |
| 1 | 1 | 1 | 0 | SCOP 55103 | FAD-linked oxidases, C-terminal domain |
| 1 | 1 | 1 | 1 | SCOP 52210 | Succinyl-CoA synthetase domains |
| 1 | 1 | 1 | 0 | SCOP 48056 | Di-copper centre-containing domain |
| 1 | 1 | 1 | 0 | SCOP 48334 | DNA repair protein MutS, domain III |
| 1 | 1 | 1 | 0 | SCOP 51011 | Glycosyl hydrolase domain |
| 1 | 1 | 1 | 0 | SCOP 52029 | GroEL apical domain-like |
| 1 | 1 | 1 | 0 | SCOP 117289 | Nucleoporin domain |
| 1 | 1 | 1 | 0 | SCOP 48431 | Lipovitellin-phosvitin complex, superhelical domain |
| 1 | 1 | 1 | 0 | SCOP 140860 | Pseudo ankyrin repeat-like |
| 1 | 1 | 1 | 0 | SCOP 48065 | DBL homology domain (DH-domain) |
| 1 | 1 | 1 | 1 | SCOP 47741 | CO dehydrogenase ISP C-domain like |
| 1 | 1 | 1 | 1 | SCOP 74924 | Cap-Gly domain |
| 1 | 1 | 1 | 0 | SCOP 55271 | DNA repair protein MutS, domain I |
| 1 | 1 | 1 | 1 | SCOP 48508 | Nuclear receptor ligand-binding domain |
| 1 | 1 | 1 | 0 | SCOP 49854 | Spermadhesin, CUB domain |
| 1 | 1 | 1 | 1 | SCOP 49417 | p53-like transcription factors |
| 1 | 1 | 1 | 0 | SCOP 56854 | Bcl-2 inhibitors of programmed cell death |
| 1 | 1 | 1 | 0 | SCOP 47769 | SAM/Pointed domain |
| 1 | 1 | 1 | 0 | SCOP 101690 | PAZ domain |
| 1 | 1 | 1 | 0 | SCOP 48097 | Regulator of G-protein signaling, RGS |
| 1 | 1 | 1 | 1 | SCOP 49599 | TRAF domain-like |
| 1 | 1 | 1 | 0 | SCOP 75632 | Cullin homology domain |
| 1 | 1 | 1 | 0 | SCOP 48050 | Hemocyanin, N-terminal domain |
| 1 | 1 | 1 | 0 | SCOP 110942 | HSP90 C-terminal domain |
| 1 | 1 | 1 | 0 | SCOP 51045 | WW domain |
| 1 | 1 | 1 | 0 | SCOP 75553 | Smc hinge domain |
| 1 | 1 | 1 | 1 | SCOP 103243 | KA1-like |
| 1 | 1 | 1 | 0 | SCOP 48168 | R1 subunit of ribonucleotide reductase, N-terminal domain |
| 1 | 1 | 1 | 0 | SCOP 54849 | GroEL-intermediate domain like |
| 1 | 1 | 1 | 0 | SCOP 54556 | Chitinase insertion domain |
| 1 | 1 | 1 | 0 | SCOP 82895 | TSP-1 type 1 repeat |
| 1 | 1 | 1 | 0 | SCOP 52156 | Initiation factor IF2/eIF5b, domain 3 |
| 1 | 1 | 1 | 0 | SCOP 49758 | Calpain large subunit, middle domain (domain III) |
| 1 | 1 | 1 | 0 | SCOP 158457 | Orange domain-like |
