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Domain assignment for gi|189083776|ref|NP_001121136.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|189083776|ref|NP_001121136.1|
Domain Number 1 Region: 6-145
Classification Level Classification E-value
Superfamily Actin depolymerizing proteins 5.38e-43
Family Gelsolin-like 0.000000283
Further Details:      
 
Domain Number 2 Region: 373-517
Classification Level Classification E-value
Superfamily Actin depolymerizing proteins 6.31e-38
Family Gelsolin-like 0.000000213
Further Details:      
 
Domain Number 3 Region: 606-722
Classification Level Classification E-value
Superfamily Actin depolymerizing proteins 1.61e-34
Family Gelsolin-like 0.000000547
Further Details:      
 
Domain Number 4 Region: 243-354
Classification Level Classification E-value
Superfamily Actin depolymerizing proteins 4.74e-29
Family Gelsolin-like 0.000000996
Further Details:      
 
Domain Number 5 Region: 126-230
Classification Level Classification E-value
Superfamily Actin depolymerizing proteins 1.45e-28
Family Gelsolin-like 0.00000225
Further Details:      
 
Domain Number 6 Region: 503-605
Classification Level Classification E-value
Superfamily Actin depolymerizing proteins 2.8e-20
Family Gelsolin-like 0.00000441
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) gi|189083776|ref|NP_001121136.1|
Sequence length 731
Comment gelsolin isoform b [Homo sapiens]
Sequence
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD
LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG
VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN
SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED
AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN
TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS
SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG
DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE
PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY
RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV
GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD
PLDRAMAELAA
Download sequence
Identical sequences gi|189083772|ref|NP_001121134.1| gi|189083774|ref|NP_001121135.1| gi|189083776|ref|NP_001121136.1| gi|189083778|ref|NP_001121137.1| gi|38044288|ref|NP_937895.1| ENSP00000340888 ENSP00000362914 ENSP00000362929 ENSP00000416586 NP_001121134.1.87134 NP_001121134.1.92137 NP_001121136.1.87134 NP_001121136.1.92137 NP_001121137.1.87134 NP_001121137.1.92137 NP_937895.1.87134 NP_937895.1.92137 XP_005252002.1.92137 XP_011516893.1.92137 XP_011516894.1.92137 XP_011516895.1.92137 ENSP00000340888 ENSP00000362914 ENSP00000362929 ENSP00000409358 ENSP00000416586

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