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Domain assignment for gi|27894285|ref|NP_612198.2| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|27894285|ref|NP_612198.2|
Domain Number 1 Region: 158-491
Classification Level Classification E-value
Superfamily Subtilisin-like 1.3e-93
Family Subtilases 0.000000000842
Further Details:      
 
Domain Number 2 Region: 487-611
Classification Level Classification E-value
Superfamily Galactose-binding domain-like 5.1e-35
Family Proprotein convertase P-domain 0.00042
Further Details:      
 
Domain Number 3 Region: 70-141
Classification Level Classification E-value
Superfamily Protease propeptides/inhibitors 2.38e-25
Family Prohormone convertase 1 pro-domain 0.0025
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) gi|27894285|ref|NP_612198.2|
Sequence length 664
Comment proprotein convertase subtilisin/kexin type 6 isoform f preproprotein [Homo sapiens]
Sequence
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEERFVSTLSILFHWSVYLSWSQYHIVLI
TVAL
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Identical sequences H7BXT3
NP_612198.2.87134 NP_612198.2.92137 gi|27894285|ref|NP_612198.2| ENSP00000332052

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