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Domain assignment for gi|61744471|ref|NP_004622.2| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|61744471|ref|NP_004622.2|
Domain Number 1 Region: 424-684
Classification Level Classification E-value
Superfamily YWTD domain 3.01e-57
Family YWTD domain 0.0000000155
Further Details:      
 
Domain Number 2 Region: 166-201
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.000000000301
Family LDL receptor-like module 0.0011
Further Details:      
 
Domain Number 3 Region: 259-295
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.000000000615
Family LDL receptor-like module 0.00067
Further Details:      
 
Domain Number 4 Region: 293-333
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.000000000903
Family LDL receptor-like module 0.00079
Further Details:      
 
Domain Number 5 Region: 46-81
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.00000000115
Family LDL receptor-like module 0.00084
Further Details:      
 
Domain Number 6 Region: 85-128
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.00000000196
Family LDL receptor-like module 0.00081
Further Details:      
 
Domain Number 7 Region: 119-164
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.00000000654
Family LDL receptor-like module 0.00069
Further Details:      
 
Domain Number 8 Region: 205-245
Classification Level Classification E-value
Superfamily LDL receptor-like module 0.0000000196
Family LDL receptor-like module 0.0011
Further Details:      
 
Domain Number 9 Region: 335-381
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000000259
Family EGF-type module 0.0019
Further Details:      
 
Domain Number 10 Region: 376-415
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000000135
Family EGF-type module 0.0019
Further Details:      
 
Domain Number 11 Region: 695-735
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000268
Family EGF-type module 0.0016
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) gi|61744471|ref|NP_004622.2|
Sequence length 963
Comment low-density lipoprotein receptor-related protein 8 isoform 1 precursor [Homo sapiens]
Sequence
MGLPEPGPLRLLALLLLLLLLLLLQLQHLAAAAADPLLGGQGPAKDCEKDQFQCRNERCI
PSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEA
TCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATLCAPHEFQCGNRSCL
AAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDE
AAELCGRPGPGATSAPAACATASQFACRSGECVHLGWRCDGDRDCKDKSDEADCPLGTCR
GDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGCSHICTDLKIGFEC
TCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGK
SPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMD
KASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLS
EPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYW
VDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGL
EISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCA
CPDTMWLGPDMKRCYRAPQSTSTTTLASTMTRTVPATTRAPGTTVHRSTYQNHSTETPSL
TAAVPSSVSVPRAPSISPSTLSPATSNHSQHYANEDSKMGSTVTAAVIGIIVPIVVIALL
CMSGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEDEDELHIGRTAQIGHVYPAAISSFDRP
LWAEPCLGETREPEDPAPALKELFVLPGEPRSQLHQLPKNPLSELPVVKSKRVALSLEDD
GLP
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Identical sequences Q14114
9606.ENSP00000303634 gi|61744471|ref|NP_004622.2| ENSP00000303634 ENSP00000303634 NP_004622.2.87134 NP_004622.2.92137 ENSP00000303634

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