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Domain assignment for gi|54607027|ref|NP_001005619.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|54607027|ref|NP_001005619.1|
Domain Number 1 Region: 129-368
Classification Level Classification E-value
Superfamily vWA-like 8.01e-72
Family Integrin A (or I) domain 0.00000203
Further Details:      
 
Domain Number 2 Region: 1128-1312
Classification Level Classification E-value
Superfamily Fibronectin type III 5.3e-36
Family Fibronectin type III 0.00000288
Further Details:      
 
Domain Number 3 Region: 1509-1710
Classification Level Classification E-value
Superfamily Fibronectin type III 1.77e-34
Family Fibronectin type III 0.001
Further Details:      
 
Domain Number 4 Region: 990-1108
Classification Level Classification E-value
Superfamily CalX-like 6.02e-20
Family CalX-beta domain 0.00083
Further Details:      
 
Domain Number 5 Region: 624-709
Classification Level Classification E-value
Superfamily Integrin beta tail domain 1.83e-18
Family Integrin beta tail domain 0.0024
Further Details:      
 
Domain Number 6 Region: 27-78
Classification Level Classification E-value
Superfamily Plexin repeat 0.00000000335
Family Plexin repeat 0.0018
Further Details:      
 
Domain Number 7 Region: 537-575
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000000273
Family Integrin beta EGF-like domains 0.019
Further Details:      
 
Domain Number 8 Region: 579-616
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000363
Family Integrin beta EGF-like domains 0.0091
Further Details:      
 
Weak hits

Sequence:  gi|54607027|ref|NP_001005619.1|
Domain Number - Region: 507-538
Classification Level Classification E-value
Superfamily EGF/Laminin 0.00781
Family Integrin beta EGF-like domains 0.045
Further Details:      
 
Domain Number - Region: 467-493
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0502
Family Integrin beta EGF-like domains 0.017
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) gi|54607027|ref|NP_001005619.1|
Sequence length 1805
Comment integrin beta-4 isoform 2 precursor [Homo sapiens]
Sequence
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDG
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCV
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFA
FPGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDY
STLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPSW
GPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNI
PNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFT
LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSP
ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQ
SEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQ
QFFQT
Download sequence
Identical sequences ENSP00000400217 gi|54607027|ref|NP_001005619.1| NP_001005619.1.87134 NP_001005619.1.92137 ENSP00000344079 ENSP00000400217

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