SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

  Home > Genomes > Loa loa v3.3 > LOAG_18091T0

Domain assignment for LOAG_18091T0 from Loa loa v3.3

Domain architecture

Domain assignment details

(show help)
Strong hits

Sequence:  LOAG_18091T0
Domain Number 1 Region: 3419-3545
Classification Level Classification E-value
Superfamily PH domain-like 6.44e-34
Family Pleckstrin-homology domain (PH domain) 0.00041
Further Details:      
 
Domain Number 2 Region: 12-133
Classification Level Classification E-value
Superfamily Spectrin repeat 8.38e-31
Family Spectrin repeat 0.00013
Further Details:      
 
Domain Number 3 Region: 1023-1175
Classification Level Classification E-value
Superfamily Spectrin repeat 1.68e-29
Family Spectrin repeat 0.00047
Further Details:      
 
Domain Number 4 Region: 1238-1388
Classification Level Classification E-value
Superfamily Spectrin repeat 8.23e-28
Family Spectrin repeat 0.00061
Further Details:      
 
Domain Number 5 Region: 2729-2879
Classification Level Classification E-value
Superfamily Spectrin repeat 1.58e-25
Family Spectrin repeat 0.0014
Further Details:      
 
Domain Number 6 Region: 2513-2656
Classification Level Classification E-value
Superfamily Spectrin repeat 1.44e-24
Family Spectrin repeat 0.0012
Further Details:      
 
Domain Number 7 Region: 2832-2986
Classification Level Classification E-value
Superfamily Spectrin repeat 1.16e-23
Family Spectrin repeat 0.00092
Further Details:      
 
Domain Number 8 Region: 1340-1494
Classification Level Classification E-value
Superfamily Spectrin repeat 3.27e-23
Family Spectrin repeat 0.00084
Further Details:      
 
Domain Number 9 Region: 2418-2561
Classification Level Classification E-value
Superfamily Spectrin repeat 7.2e-23
Family Spectrin repeat 0.00088
Further Details:      
 
Domain Number 10 Region: 3048-3201
Classification Level Classification E-value
Superfamily Spectrin repeat 9.36e-23
Family Spectrin repeat 0.002
Further Details:      
 
Domain Number 11 Region: 1455-1600
Classification Level Classification E-value
Superfamily Spectrin repeat 1.13e-22
Family Spectrin repeat 0.0019
Further Details:      
 
Domain Number 12 Region: 423-526
Classification Level Classification E-value
Superfamily Spectrin repeat 9.42e-21
Family Spectrin repeat 0.0009
Further Details:      
 
Domain Number 13 Region: 1776-1918
Classification Level Classification E-value
Superfamily Spectrin repeat 1.83e-20
Family Spectrin repeat 0.0017
Further Details:      
 
Domain Number 14 Region: 2099-2201
Classification Level Classification E-value
Superfamily Spectrin repeat 1.85e-20
Family Spectrin repeat 0.002
Further Details:      
 
Domain Number 15 Region: 1657-1823
Classification Level Classification E-value
Superfamily Spectrin repeat 1.85e-20
Family Spectrin repeat 0.0035
Further Details:      
 
Domain Number 16 Region: 1883-2033
Classification Level Classification E-value
Superfamily Spectrin repeat 3.48e-19
Family Spectrin repeat 0.0015
Further Details:      
 
Domain Number 17 Region: 2305-2457
Classification Level Classification E-value
Superfamily Spectrin repeat 1.31e-18
Family Spectrin repeat 0.0011
Further Details:      
 
Domain Number 18 Region: 202-347
Classification Level Classification E-value
Superfamily Spectrin repeat 2.06e-18
Family Spectrin repeat 0.0027
Further Details:      
 
Domain Number 19 Region: 811-936
Classification Level Classification E-value
Superfamily Spectrin repeat 4.06e-18
Family Spectrin repeat 0.0021
Further Details:      
 
Domain Number 20 Region: 706-829
Classification Level Classification E-value
Superfamily Spectrin repeat 1.92e-17
Family Spectrin repeat 0.0049
Further Details:      
 
Domain Number 21 Region: 352-455
Classification Level Classification E-value
Superfamily Spectrin repeat 0.0000000000000157
Family Spectrin repeat 0.00068
Further Details:      
 
Domain Number 22 Region: 2205-2333
Classification Level Classification E-value
Superfamily Spectrin repeat 0.0000000000000432
Family Spectrin repeat 0.0046
Further Details:      
 
Domain Number 23 Region: 544-611
Classification Level Classification E-value
Superfamily SH3-domain 0.00000000000013
Family SH3-domain 0.0013
Further Details:      
 
Domain Number 24 Region: 933-1061
Classification Level Classification E-value
Superfamily Spectrin repeat 0.00000000000015
Family Spectrin repeat 0.0013
Further Details:      
 
Domain Number 25 Region: 619-702
Classification Level Classification E-value
Superfamily Spectrin repeat 0.0000000000493
Family Spectrin repeat 0.0028
Further Details:      
 
Domain Number 26 Region: 3174-3268
Classification Level Classification E-value
Superfamily Spectrin repeat 0.000000000746
Family Spectrin repeat 0.0044
Further Details:      
 
Weak hits

Sequence:  LOAG_18091T0
Domain Number - Region: 2991-3068
Classification Level Classification E-value
Superfamily Spectrin repeat 0.023
Family Spectrin repeat 0.0038
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

(show help)

Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) LOAG_18091T0
Sequence length 3741
Comment | LOAG_18091 | Loa loa V3 beta chain spectrin (3742 aa)
Sequence 
MTGARRVAKIVGNLMSSDQLQEDYEALCSELLFWIQQTITMLNDRRFPNSLKGIQDQLLA
FKNYRTVEKPPKYKEKGELEALFFTIQTKRKAMGRKPYVPPAGLFMHDIESAWSLLDHSE
NDRQLALMSELRRQERLELMAQKFERKAGLRDAWLREMSSVLQDFDLGRNIAQVEASLKK
QQAIAADILPRESRFKSLSFMAAELSKENYHDSDKIRIRERELLDKWSQLLAALESRRRA
LLSLSDLMSLLRDIDTLSLEIRALEPQFRSRDVGKHLLGVEDLLGKQEILEAQLNSQGEL
LKNVTSQALDYIRGKGEQYDVLQKKLDDVSSLYESVVQLCQQRRITLYRARDLYRFIQDD
EEEMSWLQEKEDLCISLLKNRDLSATAQLRRIFKNLETEMEGHWQRAKGVIAAGERLVAM
GRNKEDIQTRIYNLHAKWEQLRKVVEAVGRWLREAEQAHQYFQDANEAESWIREKMPLVK
SGDYGRDEQASESLLSRHLRLEEEIQAYRADIIRLEEMARELANTEFIAGAVVRIEEDTE
ELIVPQVKMLYAYSGNNIEVKKDEILALIEKSNNDWWRVLKQDGIEGYVPANYCKVMEGE
TVTVAQTITTRKTEREPQSSRNAIMERQEAISAGYRNLNNLAEERRRLLSDVIKLYKFLR
ECDQFETWAKETETALADSTTSDNVKASRKKFNKLENEISANGKMQVKRINDVAEELVNE
GHSHRDEIRRRQDAANMLWNKIRDLLKIKQRQLEAAEKVAAFNETCEDARSWMQDKFDLL
EHKVDMNDVKAVQAVQKRYQNLGKDLKPLEEKIRFLQQLADEVKKEHPEEAARIEQMIKQ
LVKMHDELRQKSAARIEEAEQTQGHQMFDGAVKNLQTWIDKTKLALVDNTRPVDVSSAEE
LLKKHYELNDDISGKKYEFDYVRDLGQRLLQKNPALNDVRGSLKKLDTEQQAINALWKEK
ERWLKELLNLQLLNTEAERIDAATKGHEAFLELSNLGDSVETAENLLKRHSDFEAKLRAQ
EDRLKVFARGADQLIQAKHSEADFIKKRRDDVLARRSQVHQVATKRRAQLEASLQYQNLR
RNIQELSQWIAEKEKIANDDSYRDAASITMKLLKHKAFEAELKANAARLDELNAEGNALI
AARHYESESIRRMLDGVNAEWSDLLRAANAKGECLRQAEDQKGLNSALDDAHLKLDEIQA
SLNSKDLGYDLRGVKELIHKQVIVEKEMAIFEKRVLEMTEKANAMIQQGHFDSATVKKAV
QKLTERFESLKEPAKDRRTALEESLKWHQLSFDIDCEMHWISEKVPTASSEETGRSLTEA
TNMQKKHEQLEAEVASRLPHIKQTLNRSSNLIKEKHYAQEQMRAKYEQLAEALTHLNNLM
RKRKDLLDWALKEEQYMFDAAEVDSWMNEKRGALTSEDFGQDEDAAQKLLAKHKALQADM
VTYKQWLQKLAVQCKELENSNRSNNERFITRQGELEKEVETLSTLADERRQQLENAVYLY
QYLRESHDLEAWINEQLLVAMSEDYGIDYEHLKELQSRFEDFKQSVKTGSERFVHCESAA
NALLRRSPPFARDILKRQEKLRSVWSLLLDYIESRDQKLEAAEELHRFNRDVAENQERIA
EKQASIPAELGKDIKQVHSLWLKHEAFENQLGAMEQQLRELLEESVRLKATYPGGNAEHI
TAQQAALAEAWQDLQDATVSRRDMLKAAYDFQRFYVKARDLMAWTEVIVRDMQSKQAVHD
LQSVEWLQKEHLRLQRSNSSSIDSFPLAEIEAREPDFARLTSRGEQMIAKDHYASGEIAA
KLKQVGQALKQVQDEWAVRREWLSQVREWHAFQREAKQTLATIAARQATLCCAQVGGSVE
EVESQIKKVDTFQKALATLDDRVIALQKTAKQLIAARHTESSKIDQYIKQVEVALAQLRV
QLNVRKSTLDDALDLACFNSDMMEIESWIDDKQKRISAESDRQAKLTSIEDKMKRLQKHQ
AMEAELSTNESRIQEIKIRARTLASKPTNDGHDIKKRSGVILNKWDELVAMSRDQSSALE
EARDLLDFKQLVERVMRWIRERELLVSAGKMGRDMEHCQALLEKLDGTQADASVDQTSVE
SANSLGQKLIAQGRSSKDEVQQQLKDLNEAWTQVQVKLNLYRSQLRSALEVHAFNRDVDD
TCERIQEKLTAVTSDDLGRDLHSVEALIRKQEAVERDMTAHDIEAQKLLDKKPPLYSTVI
ESLQKLEASWKQLAERATARGQALMASGELHKFLDAMRKAEIWAVDALSRLTTEESPRSV
TDADAFIAKHIEKLAEIDGRQREMSELREWSTRLIAKQSDHKGEIQRALKRLQNVEHQLR
QAWEARNVALARARNRQLFADQAARAEQWLASKEAFLKQADMGESVVAVDVLLKKHYDFE
KTLIAQSDKIDALKKDADLLASCDVDYRNEIEKIRDTVLSRHAVLMDSCKRRHELLNESR
KLHEFIDSCGELMTWINANIQLAYDESFLDQTNLRVKLQKHLAFDAELEANEGRVKSMIE
VGNKLVASKHYAADQITLQIAEVKRGWDELRSKSEMKKRRLWEANEAYQLNRRIEDLEKW
LERVENDLSSEDHGKDYISVEALIKKQDDLEAEIKSRKDAVNEIVSKAHEFQKQGYATAN
ESLEMAKALEIRYNELKKPCVIRRANLNDALAFYGWISEAEEQTEWLSDRKRQTISTDYG
DTLHAIQLLTKKHAHLEADVNSRREAIARVEEKGLKMIKDGHFASNEIQEVLDELSTLLL
SVKQFMHERSQKLEDSLRSQQYYAEANEAEQWMRERMPLVANNGMGKDQAAAEGHLRRLK
TLENDINKFSDEIERLRKEVEIMLAAKHFDSTNLSSKQTKLEELYKQLSDDIARRKIQLV
DSARYHAFVRQVDGLDRWLSEKLEITKQENYGRDLAECQKLVTEFDQVVRELTSAGERIA
VVKRTQEELLRSGHPFSVSIKAKGTDLQHLWSRVNEAANERQQALQGAIQVHKFDQDADE
TLGWLEEKEAHQVALEGEDISRADLPALKQLMNKYDEFMRGVTAVEKQVNDLSREAERLI
SLYPDTQEHLVVRKMGMEEQLKDVISTANKYYEKLQQMRNLQSYFQEHRDLITWIKRLQH
AITSETLPNDVEGCKTLMLRHAEYQAEINGRQPAVDEFIRKGNNMIAAQHILSSEISAKI
RQLESAMDLLKDIWKERLVLYEENLDLQQWKRDAHITDVWLTEKEDMLKEDWRKVEDVDD
ADNKIRNFDDFLITLEAQGEKFDSLKRLTLLEKAYSKQRKKESERIRAEKGTSESRKESI
KTFEKQNKLQDRRKERERRMTQEVSLMKPSPSYTEEVYASHTLPHPRRGTEPVPCIQTSS
SESKEAPATPARQTALSVSDGSSAEAERLLKTSVLSVDETPMIQRIGSTRKTPKFTTRRS
NSLKKLKTREDFGPIDMHGYLDRKQDLQSGGKKATIRTWKRYYTILCGQLLCFFKDEDSF
LENSAASAPVNILNAECDVCPEYMKKKNTFRLKIQDGSEYLFACNDDDKMLEWVLKIRFH
ANLAPAQQLRSFDKSESPPMYSPPPRPGETLRRHTTELVSSVEVNAFSSLPYESESYEKP
GIITRNHCKFLSFHVFGIQNWNLHIYKEENLALHLRENGFENLDGPELQYLYRDKEMNGK
QVLDLDSDSMTSSTSRRNTENVKGTDSDFVAWVERQSDSSSATAAPATPTVALPDDTDSI
KKRRAFSFFKRSSRHKENSSK
Download sequence
Identical sequences A0A1S0UFZ0
XP_020305521.1.37734 LOAG_18091T0

Jump to [ Top of page · Domain architecture · Domain assignment details · Most Informative Gene Ontologies ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

Please send feedback, comments or questions to superfamily@cs.bris.ac.uk or use the feedback form.

© Copyright 2013 The SUPERFAMILY authors and Julian Gough.