The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
ENSMGAP00000012328 |
| Domain Number 1 |
Region: 16-256 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Calponin-homology domain, CH-domain |
4.18e-86 |
| Family |
Calponin-homology domain, CH-domain |
0.0000277 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 274-396 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Spectrin repeat |
2.36e-34 |
| Family |
Spectrin repeat |
0.000000247 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 510-631 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Spectrin repeat |
3.27e-31 |
| Family |
Spectrin repeat |
0.00000084 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 397-505 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Spectrin repeat |
7.46e-24 |
| Family |
Spectrin repeat |
0.00000107 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 739-867 |
| Classification Level |
Classification |
E-value |
| Superfamily |
EF-hand |
2.3e-22 |
| Family |
EF-hand modules in multidomain proteins |
0.007 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 635-746 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Spectrin repeat |
6.05e-22 |
| Family |
Spectrin repeat |
0.00000089 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Molecular Function |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
