The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
ENSONIP00000015130 |
| Domain Number 1 |
Region: 4007-4363 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Hect, E3 ligase catalytic domain |
4.19e-129 |
| Family |
Hect, E3 ligase catalytic domain |
0.0000000338 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 1621-1686 |
| Classification Level |
Classification |
E-value |
| Superfamily |
WWE domain |
1.57e-17 |
| Family |
WWE domain |
0.0022 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 1310-1362 |
| Classification Level |
Classification |
E-value |
| Superfamily |
UBA-like |
0.00000000000281 |
| Family |
UBA domain |
0.0065 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 101-179,277-469,1337-1566,1955-2007,2130-2165,2440-2472 |
| Classification Level |
Classification |
E-value |
| Superfamily |
ARM repeat |
0.00000922 |
| Family |
Plakophilin 1 helical region |
0.056 |
| Further Details: |
|
| |
| Sequence: |
ENSONIP00000015130 |
| Domain Number - |
Region: 363-418,489-640,673-690,786-830 |
| Classification Level |
Classification |
E-value |
| Superfamily |
ARM repeat |
0.0691 |
| Family |
PBS lyase HEAT-like repeat |
0.091 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Molecular Function |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
