SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Domain assignment for YOL113W from Saccharomyces cerevisiae RM11-1a

Domain architecture


Domain assignment details

(
show help)
Strong hits

Sequence:  YOL113W
Domain Number 1 Region: 357-640
Classification Level Classification E-value
Superfamily Protein kinase-like (PK-like) 1.48e-72
Family Protein kinases, catalytic subunit 0.000000124
Further Details:      
 
Domain Number 2 Region: 4-114
Classification Level Classification E-value
Superfamily PH domain-like 1.75e-18
Family Pleckstrin-homology domain (PH domain) 0.013
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

(show help)

Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) YOL113W
Sequence length 655
Comment SKM1 ORF Verified Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth
Sequence
MKGVKKEGWISYKVDGLFSFLWQKRYLVLNDSYLAFYKSDKCNEEPVLSVPLTSITNVSR
IQLKQNCFEILRATDQKENISPINSYFYESNSKRSIFISTRTERDLHGWLDAIFAKCPLL
SGVSSPTNFTHKVHVGFDPKVGNFVGVPDSWAKLLQTSEITYDDWNRNSKAVIKALQFYE
DYNGLDTMQFNDHLNTSLDLKPLKSPTRYIINKRTNSIKRSVSRTLRKGKTDSILPVYQS
ELKPFPRPSDDDYKFTNIEDNKVREEGRVHVSKESTADSQTKQLGKKEQKVIQSHLRRHD
NNATFKPHRLAPSAPATKNYDRKTKWHKEDLLELKNNDDSNEIIMKMKTVAIDVNPRPYF
QLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIM
NELLVMNDSRQENIVNFLEAYIIDDEELWVITEYMEGGCLTDILDAVVRSNTGEHSSPLN
ENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRA
TMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSP
KLRHPESVCKETKQFLDACLQVNVESRASVRKLLTFEFLSMACSPEELKVSLKWH
Download sequence
Identical sequences A0A0L8VI50 A6ZN97 B3LIV2 C7GSS3
tr|A6ZN97|A6ZN97_YEAS7 YOL113W YOL113W YOL113W SCRT_01292 YOL113W YOL113W YOL113W

Jump to [ Top of page · Domain architecture · Domain assignment details · Most Informative Gene Ontologies ]