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Domain assignment for YLR384C from Saccharomyces cerevisiae VL3

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YLR384C
Domain Number 1 Region: 141-171,239-424,553-605
Classification Level Classification E-value
Superfamily DPP6 N-terminal domain-like 0.000000000902
Family DPP6 N-terminal domain-like 0.024
Further Details:      
 
Weak hits

Sequence:  YLR384C
Domain Number - Region: 991-1125
Classification Level Classification E-value
Superfamily TPR-like 0.0298
Family Tetratricopeptide repeat (TPR) 0.059
Further Details:      
 
Domain Number - Region: 853-1004
Classification Level Classification E-value
Superfamily ARM repeat 0.0472
Family Armadillo repeat 0.07
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) YLR384C
Sequence length 1349
Comment IKI3 ORF Verified Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)
Sequence
MVEHDKSGSKRQELRSNMRNLITLNKGKFKPTASTAEGDEDDLSFTLLDSVFDTLSDSIT
CVLGSTDIGAIEVQQFMKDGSRNVLASFNIQTFDDKLLSFVHFADINQLVFVFEQGDIIT
ATYDPVSLDPAETLIEIMGTIDNGIAAAQWSYDEETLAMVTKDRNVVVLSKLYEPISEYH
LEVDDLKISKHVTVGWGKKETQFRGKGARAMEREALASLKASGLVGNQLRDPTMPYMVDT
GDVTALDSHEITISWRGDCDYFAVSSVEEVPDEDDETKSIKRRAFRVFSREGQLDSASEP
VTGMEHQLSWKPQGSLIASIQRKTDLGEEDSVDVIFFERNGLRHGEFDTRLPLDEKVESV
CWNSNSEALAVVLANRIQLWTSKNYHWYLKQELYASDISYVKWHPEKDFTLMFSDAGFIN
IVDFAYKMAQGPTLEPFDNGTSLVVDGRTVNITPLALANVPPPMYYRDFETPGNVLDVAC
SFSNEIYAAINKDVLIFAAVPSIEEMKKGKHPSIVCEFPKSEFTSEVDSLRQVAFINDSI
VGVLLDTDNLSRIALLDIQDITQPTLITIVEVYDKIVLLRSDFDYNHLVYETRDGTVCQL
DAEGQLMEITKFPQLVRDFRVKRVHNTSAEDDGNWSAESSELVAFGITNNGKLFANQVLL
ASAXTSLEITDSFLLFTTAQHNLQFVHLNSTDFKPLPLVEEGVEDERVRAIERGSILVSV
IPSKSSVVLQATRGNLETIYPRIMVLAEVRKNIMAKRYKEAFIVCRTHRINLDILHDYAP
ELFIKNLEVFINQIGRVDYLNLFISCLSEDDVTKTKYKETLYSGISKSFGMEPAPLTEMQ
IYMKKKMFDPKTSKVNKICDAVLNVLLSNPEYKKKYLQTIITAYASQNPQNLPAALKLIS
ELENSEEKDSCVTYLCFLQDVNVVYKSALSLYDVSLALLVAQKSQMDPREYLPFLQELQD
NEPLRRKFLIDDYLGNYEKALEHLSEIDKDGNVSEEVIDYVESHDLYKHGLALYRYDSEK
QNVIYNIYAKHLSSNQMYTDAAVAYEMLGKFKEAMGAYQSAKRWREAMSIAVQKFPEEVE
SVAEELISSLTFEHRYVDAADIQLEYLDNVKEAVALYCKAYRYDIASLVAIKAKKDELLE
EVVDPGLGEGFGIIAELLADCKGQINSQLRRLRELRAKKEENPYAFYGQETEQADDVSVA
PSETSTQESFFTRYTGKTGGTAKTGASRRTAKNKRREERKRARGKKGTIYEEEYLVQSVG
RLIERLNQTKPDAVRVVEGLCRRNMREQAHQIQKNFVEVLDLLKANVKEIYSISEKDRER
VNENGEVYYIPEIPVPEIHDFPKSHIVDF
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Identical sequences E7QIH7
YLR384C

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