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Domain assignment for gi|49522954|gb|AAH75266| from Xenopus (Silurana) tropicalis v7.1 (annotation v7.2)

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|49522954|gb|AAH75266|
Domain Number 1 Region: 355-545
Classification Level Classification E-value
Superfamily CAPPD, an extracellular domain of amyloid beta A4 protein 2.88e-82
Family CAPPD, an extracellular domain of amyloid beta A4 protein 0.0000000127
Further Details:      
 
Domain Number 2 Region: 28-122
Classification Level Classification E-value
Superfamily A heparin-binding domain 1.11e-43
Family A heparin-binding domain 0.00000247
Further Details:      
 
Domain Number 3 Region: 123-187
Classification Level Classification E-value
Superfamily Amyloid beta a4 protein copper binding domain (domain 2) 2.09e-29
Family Amyloid beta a4 protein copper binding domain (domain 2) 0.0000137
Further Details:      
 
Domain Number 4 Region: 284-342
Classification Level Classification E-value
Superfamily BPTI-like 2.55e-21
Family Small Kunitz-type inhibitors & BPTI-like toxins 0.00019
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) gi|49522954|gb|AAH75266|
Sequence length 750
Comment amyloid beta (A4) precursor protein [Xenopus (Silurana) tropicalis]
Sequence
MLPHITLLVLAAGALALEVPADGNAGLLAEPQIAMFCGKLNMHMNVQNGKWETDVSGTKG
CIGTKEGILQYCQDVYPELQITNVVEANQPVTIQNWCKRGRKQCKSRTHIVVPYRCLVGE
FVSDALLVPDKCKFLHQERMDICETHLHWHTVAKESCSEKSMSLHEYGMLLPCGIDKFRG
VEFVCCPTADESESFDSADAEDDSDVWWGGADADYIDRSDDKAVEAQPEEEEEVVEVEEE
EADDDEDDGDEAEEEPEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRA
MIPRWYYDVTERKCAQFIYGGCGGNRNNFDSEDYCMAVCGSVTVPATAASTPDAVDKYLE
NPNDENEHDRFLKAKERLEGKHREKMSEVMKEWEEAERQAKNLPKADKKAVIQHFQEKVE
SLEQEAANERQQLVETHMARVEAMLNDRRRIALENYITALQADPPRPRHVFNMLKKYVRA
EQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVINERMNQSFSLLYKVPAVAEEIQD
EVEELFQKEQNYSDDMVSNMVSDHRISYGNDALMPSLTETKTTVELLPVDGEFNVEDLQP
WHSFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDSEYRHDAA
YEVHHQKLVFFAEEVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTTIHHGVVEVDA
AVTPEERHLTKMQQNGYENPTYKFFEQMQN
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Identical sequences Q6DJB6
ENSXETP00000029842 NP_001005698.1.99540 gi|49522954|gb|AAH75266| gi|54020906|ref|NP_001005698|

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